All articles tagged: Dermatology

A common food dye turned mice see-through, a "stunning" finding that could revolutionize imaging techniques in medicine.

It can take up to 1 year to see a significant response with topical immunosuppressants and narrowband ultraviolet B treatment.

Low-dose oral metformin was associated with symptomatic improvement, hair regrowth, and gene expression modulation in a case series of patients with treatment-refractory central centrifugal cicatricial alopecia.

The risk for any skin cancer was higher among US veterans than among nonveterans, according to a cross-sectional study using nationally representative data collected over 20 years.

Both nonsteroidal options are fast-acting, Jashin J. Wu said.

The association of prenatal ω-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) with the risk for childhood atopic dermatitis (AD) varies based on the maternal cyclooxygenase-1 (COX1) genotype, according to a study published online Aug. 28 in JAMA Dermatology.Liang Chen, from Herlev and Gentofte Hospital in Copenhagen, Denmark, an

Nearly 80% of patients with uveal melanoma treated with tebentafusp experienced skin reactions in a small cohort study.

Several case reports about the use of topical timolol for PG have been published in the medical literature, including a case series.

More than 5 billion people globally do not consume enough iodine, vitamin E, and calcium, according to a study published online Aug. 29 in The Lancet Global Health.Simone Passarelli, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues estimated micronutrient intake using a novel approach accounting for t

This study "provides the largest longitudinal profile" of keratinocyte carcinomas in childhood cancer survivors to date, according to the authors.

The mother's COX1 genotype could influence whether prenatal fish oil supplementation affects the risk for atopic dermatitis in children, a study found.

A study found a significantly higher risk for several psychiatric disorders in Black children with vitiligo.

Dietary intake of vitamin E may potentially lower the risk for atopic dermatitis, according to a study published online Aug. 9 in Skin Research & Technology.Siqing Wang, from the Beijing University of Chinese Medicine, and colleagues conducted a Mendelian randomization analysis to explore the causal relationship between dietary

A crowdsourced registry study found associations between features of cutaneous neurofibromas and quality of life in patients with neurofibromatosis type 1.

The protocol included three laser treatments spaced 3-4 weeks apart combined with medical therapy and other energy-based devices.

People with self-identified xylazine wounds are more likely to engage in subcutaneous injection and face several barriers to seeking medical wound treatment, according to a study published online Aug. 21 in Drug and Alcohol Dependence.Raagini Jawa, from the University of Pittsburgh School of Medicine, and colleagues sought to und

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

Early childhood obesity may increase the risk for pediatric immune-mediated skin diseases, according to a study published online Aug. 21 in the Journal of Investigative Dermatology.Seong Rae Kim, M.D., from the Seoul National University College of Medicine in South Korea, and colleagues examined associations between body mass inde

The timeline for when an improved program might be in place remains unclear.

Zasocitinib showed significant efficacy in treating moderate to severe psoriasis, with 67%-68% of patients on higher doses achieving a PASI 75 score at 12 weeks.

Smoking cessation reduced the risk for hidradenitis suppurativa, eventually aligning with the risk for never smokers.

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

A beverage containing collagen peptides (CP), including tripeptides and elastin peptides (EP), is beneficial for the skin health of young and middle-aged women, according to a study published in the June issue of the Journal of Dermatologic Science and Cosmetic Technology.Shan Lu, from the Shenzhen Porshealth Bioengineering Co. in Ch

A seminal study from 2017 laid the groundwork for current approaches, Elizabeth Tanzi, MD, said.

Deciding which platforms to use and what voice or tone to adopt requires some soul-searching, according to Jessica G. Labadie, MD.

The top two procedures performed by the surveyed MedSpas are facials and hair removal.

Patients with skin of color may experience more adverse events from sclerotherapy, according to a study published online July 26 in the&nbsp;Journal of the American Academy of Dermatology.Michelle Lazar, from the Boston University School of Medicine, and colleagues characterized the incidence of common adverse events following sclerothe

The recommended treatment for patients with scleroderma was to use nerve blocks for injecting HA filler or hyaluronidase and to minimize the injection points.

The U.S. Food and Drug Administration has approved Nemluvio (nemolizumab) for adult patients living with prurigo nodularis.Nemluvio, administered as a prefilled pen for subcutaneous injection, inhibits interleukin-31 cytokine signaling, which is known to drive itch and is involved in inflammation, altered epidermal differentiation, and fibrosi

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

Continuous treatment with baricitinib is needed to maintain hair regrowth in patients with severe alopecia areata.

A study identified distinct clinical features and other differences in Hispanic patients with dermatomyositis compared with non-Hispanic patients.

The interleukin-31 inhibitor is also under FDA review for treating atopic dermatitis.

Cutaneous immune-related adverse events (cirAEs) are the most frequently reported and most visible adverse effects of checkpoint inhibition.

For patients with atopic dermatitis (AD), dupilumab maintains its clinical effectiveness up to five years and is discontinued by 23.8 percent of patients, according to a study published online Aug. 7 in JAMA Dermatology.Celeste M. Boesjes, M.D., from the University Medical Center Utrecht in the Netherlands, and colleagues examined clini

A gene expression signature in peripheral CD4+ T-cells can predict severe immune-related adverse events (irAEs) among melanoma patients treated with ipilimumab/nivolumab, according to a study published online Aug. 8 in Clinical Cancer Research.Kelsey R. Monson, Ph.D., from the Perlmutter Cancer Center at NYU Langone Health in

Sulfonamide antibiotics and cephalosporins are most strongly associated with serious cutaneous adverse drug reactions (cADRs), according to a study published online Aug. 8 in the Journal of the American Medical Association.Erika Y. Lee, M.D., from the University of Toronto, and colleagues explored the risk for serious cADRs associated w

There are racial differences in the frequency of skin biopsy for psoriasis, indicating diagnostic uncertainty, according to a research letter published online Aug. 7 in JAMA Dermatology.Fahad Ahmed, from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and colleagues conducted a cross-sectional study inv

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

U.S. doctors should be on the lookout for a more severe strain of mpox that is spreading widely in parts of Africa, federal health officials warned Wednesday.The&nbsp;alert,&nbsp;issued by the U.S. Centers for Disease Control and Prevention, came just hours after the World Health Org

Patients with alopecia areata (AA) have a higher prevalence of autoimmune and psychiatric comorbidities at time of diagnosis as well as a higher risk for new-onset autoimmune and psychiatric comorbidities after diagnosis, according to a study published online July 31 in&nbsp;JAMA Dermatology.Arash Mostaghimi, M.D., M.P.H., from Brigham

The U.S. Food and Drug Administration has approved Leqselvi (deuruxolitinib) tablets for the treatment of adults with severe alopecia areata.Leqselvi (8 mg) is a twice-daily oral selective inhibitor of the Janus kinases JAK1 and JAK2. In trials, the three most common adverse events were headache, acne, and nasopharyngitis.The approval was

The U.S. Food and Drug Administration is warning that chemical peels should not be used without the supervision of a dermatologist or other trained professional."FDA is warning consumers not to purchase or use certain chemical peel skin products without appropriate professional supervision due to risk of serious skin injuries," the agency said

Nonfinancial access barriers to care represent a persistent problem in the United States, with more than 12 percent of adults reporting being too busy to go to a provider, according to a study published online Aug. 1 in the&nbsp;National Health Statistics Reports, a publication from the National Center for Health Statistics.Amanda E. N

A relatively high proportion of dermatologists experience emergency complications during dermatological, surgical, or cosmetic procedures, according to a study published online July 20 in the Journal of Cosmetic Dermatology.Hilal Kaya Erdogan, M.D., from Eskişehir Osmangazi University in Turkey, and colleagues conducted a cross-section

Generation Z (Gen Z) patients present with a higher subjective perception of atopic dermatitis severity than millennial generation patients, according to a study published online July 25 in the&nbsp;International Journal of Dermatology.Clara Ureña-Paniego, from the University of Granada in Spain, and colleagues compared the clinical se

Most women with atopic dermatitis have impairment in sexual function, and about half consider that atopic dermatitis may influence their reproductive desire, according to a study published online June 11 in Acta Dermato-Venereologica.Juan-Angel Rodriguez-Pozo, from the Virgen de las Nieves University Hospital in Granada, Spain, and coll

Psoriasis and psoriatic arthritis may be associated with an increased risk of polyneuropathy, according to a study published online June 28 in&nbsp;Muscle &amp; Nerve.Pietro E. Doneddu, M.D., from the IRCCS Humanitas Research Hospital in Milan, and colleagues evaluated the risk and features of peripheral neuropathy in patients with psor

Hydroxychloroquine appears to be a safe and effective treatment option for anogenital lichen sclerosus that only has mild adverse effects, according to a study published online July 19 in the&nbsp;International Journal of Dermatology.Christeebella O. Akpala, from the Mayo Clinic in Rochester, Minnesota, and colleagues analyzed the demog

Use of oral corticosteroids for &gt;90 days during one year is associated with a slightly increased risk of adverse events (AEs), according to a study published online July 19 in&nbsp;JAMA Network Open.Yong Hyun Jang, M.D., Ph.D., from Kyungpook National University in Daegu, South Korea, and colleagues examined the association betwee

With respect to their lifetime prevalence of skin cancer, sexual minority (SM) adults differ across racial and ethnic groups and among males and females, according to a study published online July 17 in JAMA Dermatology.Katelyn J. Rypka, from the University of Minnesota in Minneapolis, and colleagues examined differences in the lifetime

To achieve maximal paralysis, patients injected with glabellar botulinum toxin may have significantly higher dose requirements in a high sun-exposure environment, according to a study published in the July issue of Plastic and Reconstructive Surgery.Kim L. Borsky, M.B.B.S., M.D., from the Stoke Mandeville Hospital in the United Kingdom,

Long-term exposure to air pollution is associated with the development of new psoriasis, according to a study published online July 16 in&nbsp;JAMA Network Open.Junhui Wu, Ph.D., from the Peking University School of Nursing in Beijing, and colleagues examined the association between long-term exposure to air pollution and psoriasis an

For patients experiencing migraine, direct calcitonin gene-related peptide (CGRP) inhibition with monoclonal antibodies (mAbs) is associated with reduced rates of acne and rosacea compared with no inhibition (topiramate) or indirect inhibition (triptans), according to a research letter published online July 10 in JAMA Dermatology.Chris

Seven patients with illness identified after presumed cosmetic botulinum neurotoxin (BoNT) product injection are described in a case report published in the July 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Christine M. Thomas, D.O., from the CDC in Atlanta, and colleagues charact

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

The U.S. Food and Drug Administration has approved Zoryve (roflumilast) cream, 0.15 percent, for the treatment of mild-to-moderate atopic dermatitis in adult and pediatric patients (ages 6 years and older).Zoryve is a once-daily, steroid-free cream that the company says will be available at the end of July.The approval was based on resu

Adherence to a Mediterranean diet incorporating eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) reduces skin lesions and improves quality of life in patients with acne, according to a study published online July 10 in the Journal of Cosmetic Dermatology.Anne Guertler, M.D., from Ludwig Maximilian University in Munich, and

Urban-rural disparities in skin cancer prevalence continue to persist, according to a study published in the June issue of the&nbsp;Journal of Drugs in Dermatology.Rachel R. Lin, from the University of Miami Miller School of Medicine, and colleagues used data from the Behavior Risk Factor Surveillance Survey (2018 to 2021) to compare th

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the Journal of the American Academy of Dermatology.Lea Nymand, from Bispebjerg Hospital and the University of Copenhagen in Denmark, and colleagues explored the characteristics of fatigue and it

Among patients with incompletely excised basal cell carcinoma (BCC), only about 16 percent with positive histopathologic margins have clinical recurrence, according to a study published online June 13 in Dermatology.Maria Daviti, M.D., from Aristotle University in Thessaloniki, Greece, and colleagues reported the real-life management of

For patients with prurigo nodularis (PN) and chronic pruritus of unknown origin (CPUO), abrocitinib, a Janus kinase 1 inhibitor, is effective and well tolerated, according to a study published online June 5 in JAMA Dermatology.Shawn G. Kwatra, M.D., from the University of Maryland School of Medicine in Baltimore, and colleagues examine

For patients with resected stage III melanoma, adjuvant therapy with dabrafenib plus trametinib is associated with a nonsignificant benefit in terms of overall survival, according to a study published online June 19 in the New England Journal of Medicine.Georgina V. Long, M.D., Ph.D., from the University of Sydney, and colleagues random

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

Lebrikizumab is associated with sustained effects for moderate-to-severe atopic dermatitis for up to week 52 following withdrawal of treatment, according to a study presented at the annual Revolutionizing Atopic Dermatitis Conference, held from June 8 to 10 in Chicago.Jonathan I. Silverberg, M.D., Ph.D., M.P.H., from the George Washington Unive

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

There is no evidence to suggest that administration of live vaccines to patients receiving dupilumab is unsafe, and vaccine efficacy is not affected by dupilumab, according to a position paper published online June 5 in the Annals of Allergy, Asthma &amp; Immunology.Noting that dupilumab targets the interleukin (IL)-4 receptor alpha sub

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Isotretinoin is well tolerated and effective for individuals receiving masculinizing gender-affirming hormonal therapy who have acne, according to a study published online May 29 in JAMA Dermatology.James Choe, from Brigham and Women's Hospital in Boston, and colleagues examined clinical outcomes of isotretinoin among transgender and gen

Among emergency department patients evaluated for an mpox-compatible rash, the prevalence of mpox is 1.5 percent, according to research published in the June 6 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Carl T. Berdahl, M.D., from Cedars-Sinai Medical Center in Los Angeles, and co

Neoadjuvant ipilimumab plus nivolumab followed by surgery results in longer event-free survival than surgery followed by adjuvant nivolumab among patients with resectable, macroscopic stage III melanoma, according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the American Soc

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

Long-term intermittent use of ruxolitinib cream is well tolerated and provides disease control in adolescent patients with atopic dermatitis (AD), according to a study published online May 2 in the&nbsp;American Journal of Clinical Dermatology.Lawrence F. Eichenfield, M.D., from the University of California San Diego, and colleagues asse

Bimekizumab is well tolerated and produces clinically meaningful responses in patients with hidradenitis suppurativa, according to a study published online May 22 in The Lancet.Alexa B. Kimball, M.D., from the Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues examined the efficacy and safety of b

"By examining national trends in patient visits and treatment, we may be able to better inform healthcare utilization for cutaneous wounds," Chandy said.

The finding "highlights the need for further research into tailored treatments for cardiovascular risk in psoriasis patients," Ana Ormaza Vera said.

Black patients with psoriasis had the lowest rate of switching to another biologic therapy compared with other racial and ethnic groups, suggesting possible disparities in treatment patterns.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Dupilumab will be compared with placebo in a larger multicenter randomized trial of children with alopecia.

Results from two phase 3 trials showed that topical tapinarof, once a day, was effective and safe in patients with atopic dermatitis as young as 2 years old.

Parental electronic cigarette use is associated with increased odds of pediatric atopic dermatitis (AD), according to a research letter published online May 22 in JAMA Dermatology.Gun Min Youn, from the Stanford University School of Medicine in California, and colleagues conducted a retrospective cross-sectional analysis of the 2014 to

Parental e-cigarette use was associated with an increased risk for pediatric atopic dermatitis in a retrospective, cross-sectional analysis of US population data.

Use of antihypertensive drugs was associated with a small increase in the rate of eczematous dermatitis diagnoses in older adults, with varying risks with different classes.

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a study published online May 22 in JAMA Dermatology.Morgan Ye, M.P.H., from the University of California in San Francisco, and colleagues examine

An iron profile workup and dermatological findings, such as hyperpigmentation, resistant pruritus, alopecia, and vitiligo, can help diagnose hemochromatosis.

"Our hope is that these findings provide additional data to support Mohs as the standard of care for primary surgical treatment of high-stage cSCC," the study's lead author said.

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

Consensus was reached during an in-person meeting attended by 34 individuals with diverse backgrounds.

The ideal candidate "is averse to using systemic agents but whose disease is beyond the point where topical medicines alone will work," Craig A. Elmets, MD, said.

In pediatric patients, acrochordons may be a marker for metabolic disease, according to a study published online April 29 in Pediatric Dermatology.Rachel K. Greene, M.D., from the University of Michigan in Ann Arbor, and colleagues conducted a single-center retrospective cohort study of outpatient dermatology patients between Jan. 1, 20

There is persistent growth in eBT/SRT by a small but expanding proportion of general dermatologists.

Individuals with BRCA1-associated protein (BAP1) have a high rate of nail abnormalities consistent with onychopapillomas, according to a study published online May 17 in JAMA Dermatology to coincide the annual meeting of the Society for Investigative Dermatology, held from May 15 to 18 in Dallas.Alexandra Lebensohn, from the Nat

More research is "needed to elucidate the unique features of elderly AD in pathophysiology and optimal treatments," the study authors wrote.

Tinea pedis, chronic kidney disease, peripheral vascular disease, and type 2 diabetes were associated with an increased risk for onychomycosis in patients with onychodystrophy.

Acrochordons (skin tags) in children and adolescents may serve as a marker for metabolic diseases.

Overall, version 4.0 of the AI tool performed better than version 3.5.

Adverse effects associated with using the antifibrinolytic were rare.

Non-Hispanic Black (NHB) melanoma patients have distinct tumor characteristics, presenting with more advanced disease and exhibiting worse outcomes, according to a study published in the May issue of the Journal of Surgical Oncology.Jessica A. Steadman, M.B.B.S., from the Mayo Clinic in Rochester, Minnesota, and colleagues examined fe

In its biennial Cancer Disparities Progress Report published today, the American Association for Cancer Research presents the latest statistics on disparities in cancer progress experienced by ethnic-minority groups and other medically underserved populations in the United States.Robert A. Winn, M.D., from the Virginia Commonwealth Un

Exposure to hormones, hyperpigmenting drugs, and multiparity increased risk for melasma across different racial groups in a US study of a diverse population.

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Factors associated with an increased risk for hydroxychloroquine retinopathy have been identified and include female sex, older age, and chronic kidney disease stage 3 or greater, according to a study published online May 9 in JAMA Network Open.April M. Jorge, M.D., from Massachusetts General Hospital in Boston, and colleagues identified

Psoriatic arthritis (PsA) and atopic dermatitis (AD) can coexist, and the presence of both conditions may mean special attention should be given to selecting optimal treatment, according to a study published online April 17 in the Journal of Personalized Medicine.Georgiana Strugariu, from "Grigore T. Popa" University of Medicine and Phar

Most ongoing trials of HS treatments are for moderate to severe disease, Dr Jennifer L. Hsiao said.

Healthcare delivery costs are rising, but there has been a lag in the increase in dermatologic procedure reimbursement rates.

"Early HS can mimic an intense folliculitis or furuncles that can sometimes be caused by Staphylococcus infections," Sayed said.

Physicians' assessment of disease severity and visibility may underestimate the disease's effects on the patient, data suggested.

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

In contrast to earlier findings, immunosuppression was an independent risk factor for disease-specific death and major poor outcomes.

Treatment with adalimumab was associated with improvements in common hematologic abnormalities in patients with hidradenitis suppurativa, particularly in responders.

A pediatric dermatologist proposes a four-step approach to using shared decision-making (SDM) when caring for children and adolescent patients with acne and other skin conditions.

Of the cases accruing in the United States and elsewhere, most but not all were linked to inborn errors of immunity.

Trifarotene plus skin care is beneficial for patients with moderate acne vulgaris (AV) and acne-induced hyperpigmentation (AIH), according to a study published online April 29 in the International Journal of Dermatology.Andrew Alexis, M.D., M.P.H., from Weill Cornell Medical College in New York City, and colleagues conducted a phase IV

Systemic antibiotic exposure in the first year of life is associated with higher atopic dermatitis (AD) risk in a dose-response fashion, according to a study published online April 24 in the&nbsp;Journal of Allergy and Clinical Immunology.Courtney Hoskinson, from the University of British Columbia in Vancouver, Canada, and colleagues e

The IPC's definition and diagnostic criteria for GPP minimized the complexity of clinical considerations to speed treatment of this potentially life-threatening condition.

Antiepileptic and anti-infectious agents were the most common classes tied to SJS-TEN.

Certain minority populations may be at a higher risk of being prescribed opioids post-operatively, which may confer further risks of complications of chronic opioid use.

Almost three quarters of survey respondents reported experiencing psychological and emotional stress or burnout associated with being a Mohs surgeon and 68% reported a musculoskeletal injury.

The survey included 81 dermatologists and 182 medical oncologists at six US-based academic institutions.

A review covers the various skin manifestations seen in patients with CF, which include those related to the disease itself, and those associated with treatments for CF.

Despite improved survival rates and guideline recommendations, many eligible patients with metastatic Merkel cell carcinoma are not receiving immunotherapy.

A machine learning algorithm can identify patients with common variable immunodeficiency disease (CVID) from their electronic health records, according to a study published in the May 1 issue of Science Translational Medicine.Due to the low prevalence and extensive heterogeneity in CVID phenotypes, resulting in delayed diagnoses and tre

A retrospective review that may be the first to examine the topic found differences in mpox symptoms between White non-Hispanic patients and patients of color.

Treatment with methotrexate was not associated with an increased risk for interstitial lung disease (ILD) in patients with dermatomyositis.

Health care professionals should consider stigmatization and bullying in assessing the social and mental health of children and adolescents with chronic skin diseases, according to a study published online April 24 in JAMA Dermatology.Amy S. Paller, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and col

Surface anesthesia prior to thermomechanical fractional injury therapy for wrinkles around the eyes provided adequate comfort, with positive treatment outcomes, a small study found.

A decision on approval is expected in the fourth quarter of 2024.

Healthcare professionals should be aware of the possibility of stigmatization and bullying when assessing the social and mental health of children and adolescents with chronic skin disorders.

"The potential risk of subsequent cardiovascular disease should be considered in the care of patients with PN," according to the study authors.

Pz-cel, which comprises autologous, COL7A1 gene–corrected epidermal sheets, was designed to enable normal type VII collagen expression and facilitate wound healing and pain reduction in RDEB wounds.

Tobacco smoking is negatively associated with resolution of psoriasis symptoms, according to a study published in the April issue of Tobacco Induced Diseases.Yan Qiang, from the School of Medicine at Tongji University in Shanghai, and colleagues explored the influence of smoking on treatment efficacy in patients with psoriasis. The

A calcitonin gene-related peptide inhibitor that is FDA-approved for migraine prevention showed early promise against treatment-resistant redness and flushing of rosacea.

Atopic dermatitis (AD) negatively impacts patients’ mental health (MH), especially when a patient has severe AD, according to a study published online March 14 in&nbsp;Dermatitis.Jessica K. Johnson, M.P.H., from the National Eczema Association in San Rafael, California, and colleagues evaluated patient-reported MH symptoms and their c

The authors "identified a need for expert-based guidelines for prescribing and monitoring LDOM use in hair loss patients."

Expect intradermal injections of botulinum toxin A for the improvement in the appearance of pores, sebum, skin texture, and rosacea to gain a foothold in dermatology practices, one expert says.

A small study of the 2910-nm erbium-doped fluoride glass fiber laser for facial ablation showed that patients had faster recovery times and less pain than with conventional lasers.

An analysis evaluated growth in a study of 1326 children with AD younger than 12 years.

Cutaneous manifestations of myelodysplastic syndrome (MDS) are described in a perspective piece published in the April issue of Skin Health and Disease.Xiang Li Tan, M.B.B.S., from St. George's University Hospitals NHS Foundation Trust in London, and colleagues conducted a systematic review to examine the prevalence, types, and prognos

A 532-nm picosecond laser with fractional-beam microlens array to treat solar lentigines resulted in a lower hyperpigmentation rate in patients with darker skin types, vs the full-beam approach.

A registry of adverse events from dermatologic procedures found that blistering, hypopigmentation, scars, and burns are the most common complications from laser and energy devices.

Laser and light hair treatments, with and without other treatments, improve hirsutism and related psychological measures in women with PCOS.

Once-weekly PDL treatment in infants led to near-total or total clearance of PWB and was well-tolerated in 10 infants, suggesting further investigation of the reduced treatment interval of 1 week.

The anticalcitonin gene-related peptide-receptor monoclonal antibody erenumab is effective and safe for treatment of rosacea-associated erythema and flushing, according to a study published online April 17 in JAMA Dermatology.Nita K.F. Wienholtz, M.D., Ph.D., from Copenhagen University Hospital-Rigshospitalet in Denmark, and colleag

Rapidly progressive interstitial lung disease was diagnosed in almost half of the patients with MDA5 antibody-positive dermatomyositis.

Reactions have included blurry vision, double vision, drooping eyelids, difficult swallowing or breathing, and other symptoms of botulism.

Counterfeit or mishandled Botox shots have triggered harmful reactions in 19 people in nine states, U.S. health officials warned Monday.In its alert, the U.S. Centers for Disease Control and Prevention said nine people had been hospitalized and four we

Study finds that people who have complications after cosmetic procedures have higher rates of depression, anxiety, and other mental health issues than before the procedures.

The American Society for Dermatologic Surgery Association emphasized the risks for medical procedures in unlicensed settings.

In this literature review, researchers found that neuromodulators and dermal fillers are useful and safe in SOC populations, although more data are needed in some groups.

Pediatric dermatology-rheumatology combined clinics improve patient outcomes and satisfaction.

Reports of keratoacanthomas and squamous cell carcinomas associated with the use of PD-1/PD-L1 inhibitors appeared to be relatively rare.

Response curves have continued to climb for as long as patients are followed, allowing many with disappointing early results to catch up, according to data presented at the AAD meeting.

Over 1 year after phase 3 studies suggested that delgocitinib cream was safe and effective for chronic hand eczema, extension data indicate that control persists without new safety issues.

Efficacy and safety of the two formulations were directly compared in a randomized, controlled, double-blind study of men with AGA conducted in Brazil.

"This study explored why dermatologists still prescribe a good number of long-term antibiotics for people with acne," the study's senior author Howa Yeung, MD, MSc, said in an interview.

Multiple salient factors affect long-term antibiotic prescribing practices for acne, according to a study published online April 3 in JAMA Dermatology.Ronnie A. Festok, from the Emory University School of Medicine in Atlanta, and colleagues conducted a qualitative study assessing data collected from stakeholders (dermatologists, inf

Stabilized bioactive retinol is efficacious for improving signs of photoaging, without causing major irritation, according to a study published in the April issue of the Journal of Drugs in Dermatology.Patricia Farris, M.D., from Tulane University School of Medicine in New Orleans, and colleagues examined the comprehensive efficacy

Individuals with zoom dysmorphia tend to scrutinize their facial features and fixate on what they think needs to improve and feel pressured to appear perfect before virtual meetings.

A prospective Swedish study reported that childhood atopic dermatitis is linked to an increased risk for inflammatory bowel disease.

Phase 4 involves initiating therapy, which includes demonstrating empathy by reflecting on the detrimental effects of the patient's reported sensations on their quality of life.

Sonelokimab is a novel humanized nanobody that selectively binds to interleukin (IL)-17A and IL-17F.

The U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults with Staphylococcus aureus bloodstream infections, adults with acute bacterial skin and skin structure infections, and adult and pediatric patients (age 3 months

Recent research sheds light on varying skin cancer risk, and a predictive tool offers guidance on screening in solid organ transplant recipients.

With sparse guidance regarding best practices for IHC in melanoma diagnosis, more research is needed to optimize use of IHC in this setting, according to the authors.

Bimekizumab is currently approved in the United States for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.

Alopecia, dysesthesia, and other types of skin sensations have been reported in patients treated with semaglutide, but more research is needed to understand skin findings associated with this drug.

Patients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a study published online March 19 in the Journal of the American Academy of Dermatology.Lauren Banner, from Thomas Jefferson University in Philadelphia, and colleagues used the Surveillance, Epidemiolo

Rilzabrutinib did not meet primary or secondary endpoints in the phase 3 PEGASUS trial of patients with pemphigus vulgaris or foliaceus.

Treatment with the topical JAK inhibitor reduced abscess and inflammatory nodules in a phase 2 randomized, controlled trial in patients with mild hidradenitis suppurativa.

Alternatives to SA and cryotherapy for warts may be helpful "for patients who have failed traditional therapies or have a contraindication to the usual go-tos," said Dr Jennifer Adams.

Two JAK inhibitors for non-segmental vitiligo showed better skin clearance in phase 2b trial extensions — ritlecitinib plus twice-weekly doses of UVB light and upadacitinib.

Study found that hypoplastic pitted amelogenesis imperfecta is among the oral manifestations of Kindler epidermolysis bullosa, underscoring the need for early and sustained dental care.

Pediatric longitudinal melanonychia may look like subungual melanoma in adults, but a low probability of malignancy makes clinical monitoring a reasonable noninvasive management strategy.

U.S. physicians received $12.13 billion from industry from 2013 to 2022, according to a research letter published online March 28 in the Journal of the American Medical Association.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and colleagues examined the distribution of payments within and across specialties and the medica

Some pain-relieving skin products contain potentially harmful doses of the numbing agent lidocaine and should be avoided, the U.S. Food and Drug Administration warns.These creams, gels, sprays and soaps are marketed for topical use to relieve the pain of cosmetic procedures like microdermabrasion, laser hair removal, tattooing and <a href="http

The warning applies to unapproved products illegally marketed for topical use to relieve pain before, during, or after cosmetic procedures.

Products containing glyoxylic acid were associated with the accumulation of calcium oxalate crystals in the kidneys.

Time spent on social media and use of photo-editing applications contribute to the desire to undergo a cosmetic procedure, according to a study recently published in the&nbsp;Journal of Clinical and Aesthetic Dermatology.Iman F. Khan, M.D., M.P.H., from Boston University, and colleagues surveyed 175 adults visiting an outpatient dermat

Many patients, including those with the greatest care needs, choose telemedicine even when in-person visits are available, according to a study published online March 22 in&nbsp;JAMA Network Open.Eva Chang, Ph.D., M.P.H., from Advocate Health in Milwaukee, Wisconsin, and colleagues assessed patient characteristics associated with telem

Most patients report an increase in trust in the quality of their medical care if asked for permission to use their images for research or education, according to a research letter published online March 13 in JAMA Dermatology.Trina Salvador, from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues conducted a s

Physicians express largely negative views about the impact of private equity (PE) on the health care system, according to a research letter published online March 11 in&nbsp;JAMA Internal Medicine.Jane M. Zhu, M.D., from Oregon Health and Science University in Portland, and colleagues conducted a survey to assess physicians' views towa

In a citizen's petition, Valisure asked the FDA to recall acne products with benzoyl peroxide, stirring debate.

Life expectancy increased to 77.5 years in 2022, while the age-adjusted rate of drug overdose deaths increased from 2002 to 2022 but did not change from 2021 to 2022, according to two March data briefs published by the National Center for Health Statistics.Kenneth D. Kochanek, from the National Center for Health Statistics in Hyattsville, Mar

Artificial intelligence is coming to clinical dermatology, but its enormous promise for improving the lives of patients and physicians will depend on addressing the expected problems.