All articles tagged: Gastroenterology

In updating their recommendations for the first time in nearly a decade, the ACG/ASGE Task Force highlighted four quality indicators considered a particularly high priority.

More than half of patients with IBD who failed to initially respond to the standard HBV vaccination schedule eventually benefited from enhanced revaccination strategies.

Liver grafts from hepatitis C virus-positive (HCV+) donation after circulatory death (DCD) donors have one-year patient and graft survival comparable with that of donation after brain death (DBD) liver grafts from donors with or without HCV infection, according to a study published online Aug. 22 in Transplantation.Sai Rithin Pu

An overgrowth of gut microorganisms that produce methane could be a cause of severe constipation in many people, a new review finds.

More than 5 billion people globally do not consume enough iodine, vitamin E, and calcium, according to a study published online Aug. 29 in The Lancet Global Health.Simone Passarelli, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues estimated micronutrient intake using a novel approach accounting for t

Fecal immunochemical tests (FITs) have variable sensitivity and specificity for detecting advanced colorectal neoplasia (ACN), according to a study published online Sept. 3 in the Annals of Internal Medicine.Barcey T. Levy, M.D., Ph.D., from the University of Iowa Carver College of Medicine in Iowa City, and colleagues compared the per

A team of Mayo Clinic researchers has developed an innovative computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses and other microorganisms within the digestive system, to provide insights into overall well-being.

Fecal immunochemical tests (FITs) have variable sensitivity and specificity for detecting advanced colorectal neoplasia (ACN), according to a study published online Sept. 3 in the Annals of Internal Medicine.

In the setting of isocaloric eating, time-restricted eating did not reduce weight or improve glucose homeostasis relative to a usual eating pattern, a small randomized controlled trial found.

An online nutrition education program for patients following sleeve gastrectomy attracted substantial interest, primarily among women, and received positive reviews, but more study is needed.

A dietary pattern centered around processed foods was associated with a known microbial signature of CRC and correlated with an elevated risk for its development.

Patients with early-onset colorectal cancer (EO-CRC) living in rural areas have lower five-year survival rates than their urban-dwelling counterparts, according to a research letter published online Aug. 28 in JAMA Network Open.Meng-Han Tsai, Ph.D., from the Georgia Prevention Institute at Augusta University, and colleagues examine

Statin usage in patients with MASLD is associated with a lower long-term risk for all-cause mortality, liver-related events, and progression of liver stiffness.

In patients with abdominal pain and gallstones, a more restrictive approach may avoid unnecessary cholecystectomies, with no difference in five-year outcomes, according to a study published online Aug. 21 in JAMA Surgery.Daan J. Comes, M.D., from Radboud University Medical Centre in Nijmegen, Netherlands, and colleagues evaluated

People with chronic liver disease (CLD) have a higher likelihood of barriers to health care, according to a study recently published in Gastro Hep Advances.Carrie R. Wong, M.D., Ph.D., from the University of California in Los Angeles, and colleagues compared the probability of barriers and recurrent acute care use among persons w

Potential mechanisms and therapeutic targets point the way toward a more personalized approach to IBD management.

Adult patients with inflammatory bowel disease (IBD) and respiratory syncytial virus (RSV) infection have an increased risk for hospitalization, according to a study published online in the August issue of The American Journal of Gastroenterology.Ryan A. Smith, M.D., from University of Wisconsin in Madison, and colleagu

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed a probiotic-based therapeutic that synergistically restores intestinal redox and microbiota homeostasis. This therapeutic effectively relieved inflammation and reduced colonic damage in mouse and non-human primate (NHP) models of colitis. The study is published in Cell Host & Microbe.

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

For salvage for biliary access in patients with benign biliary disease and difficult bile duct cannulation, the endoscopic ultrasound-guided rendezvous technique (EUS-RV) and precut sphincterotomy have similar success rates and comparable, acceptable complication rates, according to a study published online Aug. 27 in the Annals of Internal Medici

Stretching and meditation both help reduce muscle cramp severity for individuals with cirrhosis, according to a study published online June 11 in Liver International.Elliot B. Tapper, M.D., from the University of Michigan in Ann Arbor, and colleagues compared the effectiveness of stretching or meditation for 35 days in 98 patients

Cleveland Clinic–led research identified geographic "hot spots" across the United States where increased colorectal cancer screening is needed to improve outcomes in Hispanic or Latina communities.

Regular use of aspirin was associated with significantly greater reduction in risk for colorectal cancer among adults with less healthy lifestyles, a large observational study found.

Capsule endoscopy and double-balloon enteroscopy identified complications beyond the reach of conventional bidirectional endoscopy in patients with celiac disease who have persistent symptoms.

Guidelines say screening and surveillance can end at age 75, but many people continue to receive colonoscopies well after that time. Is there an optimal time to stop?

: In patients with acute pancreatitis, concomitant chronic liver disease more than doubles the odds of in-hospital mortality and leads to higher rates of complications.

Televisit-delivered outpatient care for inflammatory bowel disease (IBD) is not associated with a higher risk for IBD-related hospitalization, according to a study published in the August issue of The American Journal of Gastroenterology.Shirley Cohen-Mekelburg, M.D., from the VA Center for Clinical Management Research in

ALD's prevalence is increasing in all populations. However, recent data suggest that women, ethnic and racial minority groups, and young adults require special consideration.

Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) can be identified using an index of symptoms, which differs for school-aged children and adolescents, according to a study published online Aug. 21 in the Journal of the American Medical Association.Rachel S. Gross, M.D., from the NYU G

Patients treated with neoadjuvant immune checkpoint inhibitor (ICI)-based therapy for hepatocellular carcinoma (HCC) have higher-risk disease features but achieve outcomes comparable to those undergoing upfront surgery, according to a study published online Aug. 15 in Cancer Research Communications.Mari Nakazawa, M.D., from the Johns

Esoproedict can stratify Barrett esophagus (BE) patients as having a low or high risk for progression, according to a study published online Aug. 14 in the American Journal of Gastroenterology.Sarah E. Laun, Ph.D., from Previse in Baltimore, and colleagues validated Esopredict, a prognostic assay based on DNA methylation levels that s

In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists at Scripps Research have discovered why: a small molecule produced by the worms' intestines during fasting travels to the brain to block a fat-burning signal during this time.

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

Cold snare endoscopic mucosal resection (EMR) may be a safe therapeutic option for selected large colorectal polyps, thanks to a safety profile superior to that of hot EMR.

Using a new classification of steatotic liver disease (SLD) based on the presence of metabolic dysfunction and alcohol consumption, metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD) are significantly associated with the new onset of chronic kidney disease (CKD), according to a study published o

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

Nonstatin cholesterol absorption inhibitors may be associated with a reduced risk for primary liver cancer, whereas bile acid sequestrants may increase that risk.

Non-statin cholesterol absorption inhibitors may be associated with a reduced risk for primary liver cancer, whereas bile acid sequestrants may increase that risk.

The risk for patient death associated with low nurse staffing is only partly alleviated by using temporary staff to fill shortfalls, according to a study published online Aug. 19 in&nbsp;JAMA Network Open.Peter Griffiths, R.N., Ph.D., from the University of Southampton in the United Kingdom, and colleagues explored the association betwe

Cancers of the digestive system mainly include esophageal, gastric, liver, gallbladder, pancreatic, and colorectal cancers. With an estimated 20 million new cases, colorectal cancer is the third-most common cancer and the second leading cause of cancer-related deaths, closely followed by gastric and liver cancers, which are the fifth- and third-leading causes of deaths, respectively.

Perdue Foods has recalled over 167,000 pounds of chicken nuggets and tenders after consumers complained of finding bits of metal in the products.The recall covers select lots of Perdue Breaded Chicken Tenders, Butcher Box Organic Chicken Breast Nuggets and Perdue Simply Smart Organics Breaded Chicken Breast Nuggets.No injuries or adverse

Automated multiorgan computed tomography (CT), including visceral fat, can predict diabetes and associated cardiometabolic conditions, according to a study published online Aug. 6 in Radiology.Yoosoo Chang, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues examined the ability of automate

For patients with hepatocellular carcinoma (HCC), immune checkpoint inhibitor (ICI) use prior to liver transplant (LT) does not worsen outcomes, according to research published online July 10 in the Journal of Hepatology.Mohammad Saeid Rezaee-Zavareh, from the Middle East Liver Diseases Center in Tehran, Iran, and colleagues summarized

The Fracture Risk Assessment Tool had high specificity in predicting major osteoporotic fractures.

People who live with at least two other people in their first year of life and have a dog during childhood may be at reduced risk of developing Crohn’s disease.

A new stool-based syndecan-2 methylation test may improve the detection of colorectal cancer and advanced colorectal neoplasia, based on a prospective, real-world study.

A meta-analysis found that misoprostol is highly effective in treating NSAID- or aspirin-induced small bowel injuries, whereas rebamipide offers modest protection against such injuries.

British drugmaker GSK said on Friday it would seek a dismissal of an upcoming Zantac case in Florida, where plaintiffs alleged that its discontinued heart burn drug had...

Livdelzi significantly improves liver biomarkers of disease activity and bothersome symptoms of pruritus in adults with primary biliary cholangitis.

Gastroesophageal reflux disease (GERD) increases the risk for rheumatoid arthritis (RA), according to a study published online Aug. 1 in&nbsp;Scientific Reports.Quan Yuan, from the First Hospital of Jilin University in Changchun, China, and colleagues used Mendelian randomization (MR) to assess the causal relationship between GERD an

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

Several gastroenteritis-causing infectious agents, including pro-inflammatory bacteria and SARS-CoV-2, were associated with increased odds of developing IBS and functional dyspepsia.

While blood tests are better than nothing, they cannot be recommended to replace established CRC screening methods.

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States. By identifying the critical role the urea cycle plays in its development, his findings could pave the way for new medications to treat this currently incurable disease.

In a large case-control study, FIT was associated with a 33% reduction in the risk for death from colorectal cancer, supporting its use in population-based screening efforts.

An AI model significantly improved the accuracy of diagnosing solid lesions in the pancreas among both novice and experienced endoscopists in a randomized trial.

The assessment of cancer risk based on symptoms, age, and sex can be enhanced by considering information from common blood test results among patients presenting with nonspecific abdominal symptoms, according to a study published online July 30 in PLOS Medicine.Meena Rafiq, M.D., Ph.D., from University College London, and colleagues quan

The incidence rate of hepatitis C virus (HCV) reinfection was 4.7 per 100 person-years among men who have sex with men (MSM) with HIV who cleared HCV, according to a study published online July 18 in Clinical Infectious Diseases.Daniel S. Fierer, M.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues co

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

There is a complex interaction among social determinants of health with mortality risk, but a scoring system is able to identify subgroups with a high risk for mortality, according to a study published online Aug. 5 in BMJ Open.Marie-Pier Bergeron-Boucher, Ph.D., from the Interdisciplinary Centre on Population Dynamics at Syddansk Uni

Aspirin use is associated with a reduction in colorectal cancer (CRC) risk, with the greatest reduction seen among those with the unhealthiest lifestyle scores, according to a study published online Aug. 1 in JAMA Oncology.Daniel R. Sikavi, M.D., from Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues ex

Metabolic dysfunction-associated steatotic liver disease (MASLD)-related and metabolic and alcohol-related liver disease (MetALD)-related cirrhosis is responsible for one-third of cirrhosis cases seen in the intensive care unit (ICU), according to a study published online July 22 in&nbsp;Alimentary Pharmacology and Therapeutics.Philippe

An estimated 15 million U.S. adults consumed at least one of six potentially hepatotoxic botanicals within the previous 30 days, according to a study published online Aug. 5 in JAMA Network Open.Alisa Likhitsup, M.D., M.P.H., from the University of Michigan in Ann Arbor, and colleagues assessed the prevalence and clinical characteristics

For patients with gastroesophageal reflux disease (GERD), improvement in symptoms is seen with both antireflux mucosectomy (ARMS) and antireflux mucosal ablation (ARMA), but subjective and objective indicators of outcomes are better with ARMS than ARMA, according to a study published online June 21 in Digestive Endoscopy.Ah Young Lee, M.

For patients with gastroesophageal reflux disease (GERD), improvement in symptoms is seen with both antireflux mucosectomy (ARMS) and antireflux mucosal ablation (ARMA), but subjective and objective indicators of outcomes are better with ARMS than ARMA, according to a study published online June 21 in Digestive Endoscopy.

Millions of Americans use the opioid-like herbal supplement known as kratom, but evidence of its dangers continue to mount.The U.S. Food and Drug Administration has issued <a href="https://www.fda.gov/food/alerts-advisories-safety-information/fda-warns-consumers-not-use-optimized-plant-mediated-solutions-opms-black-liquid-kratom?utm_medium=email&a

Fecal microbiota transplantation (FMT) is safe but does not offer clinically meaningful improvements for Parkinson disease (PD), according to a study published online July 29 in&nbsp;JAMA Neurology.Filip Scheperjans, M.D., Ph.D., from Helsinki University Hospital, and colleagues randomly assigned (2:1) 47 patients with PD (aged 35 to 75

Younger birth cohorts have an increased incidence of many common cancer types, according to a study published in the August issue of The Lancet Public Health.Hyuna Sung, Ph.D., from the American Cancer Society in Atlanta, and colleagues obtained incidence data for 34 types of cancer and mortality data for 25 types of cancer for individ

For patients undergoing open or laparoscopic resection of the small bowel or strictureplasty for Crohn disease (CD), small bowel resection is associated with the longest length of stay and increased odds of postoperative wound complications, according to a study published online July 29 in the International Journal of Colorectal Disease.<

From 1999 to 2020, age-adjusted esophageal cancer mortality decreased among Black adults but stabilized among White adults, reducing the racial mortality gap, according to a study published online July 24 in the Journal of Gastroenterology and Hepatology.Chun-Wei Pan, M.D., from the John H. Stroger, Jr., Hospital of Cook County in Ch

The use of cholesterol absorption inhibitors is associated with a reduced risk for liver cancer, according to a study published online July 29 in&nbsp;Cancer.Shahriar A. Zamani, Ph.D., from the National Cancer Institute at the National Institutes of Health in Rockville, Maryland, and colleagues examined the risk for liver cancer for

Eye-level communication by clinicians appears beneficial compared with standing at the bedside of inpatients, according to a review published online July 17 in the&nbsp;Journal of General Internal Medicine.Nathan Houchens, M.D., from the University of Michigan Medical School in Ann Arbor, and colleagues conducted a systematic literatur

Pesticide usage is associated with an increased incidence of cancer, according to a study published online July 25 in Frontiers in Cancer Control and Society.Jacob Gerken, D.O., from the Rocky Vista University College of Osteopathic Medicine in Englewood, Colorado, and colleagues examined the relationship between pesticides and cancer

A study reported in Proceedings of the National Academy of Sciences (PNAS) shows how the presence of a specific protein called IL-22BP affects the composition of the gut microbiota and the body's response to bacterial infection.

Reductions in processed meat and unprocessed red meat consumption could result in fewer occurrences of type 2 diabetes, cardiovascular disease, colorectal cancer, and all-cause deaths, according to a study published in the July issue of The Lancet Planetary Health.Joe Kennedy, Ph.D., from the University of Edinburgh in the United Kingdo

Transgender adults have higher prevalence of cirrhosis, but they do not have increased incidence of liver-related outcomes or all-cause mortality, according to a study published online June 25 in the American Journal of Gastroenterology.Hirsh Elhence, from the Keck School of Medicine at the University of Southern California in Los Angel

The U.S. Food and Drug Administration on Monday approved a new blood test that can spot colon cancer.In late May, an FDA advisory panel had voted 7-2 that the benefits outweigh the risks when using the Guardant Health's Shield test for&n

Researchers at UCLA Health uncovered new information about the role inflammation plays in mitigating liver fibrosis, which is associated with metabolic-associated fatty liver disease (MAFLD), one of the most common diseases in the world affecting up to 40% of U.S. adults.

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis.

Expensive MRI exams are commonly used to evaluate patients with suspected gallstones, often delaying definitive intervention and increasing the risk of disease severity, further complications and longer hospital stays.

In a clinical guideline issued by the American College of Gastroenterology and published online in the July issue of The American Journal of Gastroenterology, updated recommendations are presented for the diagnosis and management of the most common focal liver lesions (FLL).Catherine Frenette, M.D., from the Family Health Centers of Sa

Screening with fecal immunochemical tests (FITs) lowers the risk of dying from colorectal cancer (CRC), according to a study published online July 19 in&nbsp;JAMA Network Open.Chyke A. Doubeni, M.D., from The Ohio State University College of Medicine in Columbus, and colleagues evaluated whether FIT screening is associated with a lower

In a clinical guideline issued by the American College of Gastroenterology and published online in the July issue of The American Journal of Gastroenterology, updated recommendations are presented for the diagnosis and management of the most common focal liver lesions (FLL).

A joint artificial intelligence (AI)-assisted model integrating clinical information and endoscopic ultrasonographic (EUS) images improves diagnosis of solid lesions in the pancreas, according to a study published online July 19 in JAMA Network Open.Haochen Cui, M.D., from Tongji Hospital in Wuhan, China, and colleagues developed a mult

For solid organ transplant recipients, gut dysbiosis is associated with all-cause and cause-specific mortality, according to a study published online July 2 in Gut.J. Casper Swarte, from the University Medical Centre in Groningen, Netherlands, and colleagues analyzed 1,337 metagenomes derived from fecal samples of 766 kidney, 334 live

For patients with moderate-to-severe Crohn disease, risankizumab is noninferior to ustekinumab for clinical remission at week 24 and is superior for endoscopic remission at week 48, according to a study published in the July 18 issue of the New England Journal of Medicine.Laurent Peyrin-Biroulet, M.D., Ph.D., from the INFINY Institut

Two studies from Michigan Medicine may provide hope for patients with irritable bowel syndrome struggling to implement the traditional low-FODMAP diet.

A considerable proportion of individuals experiencing acute gastroenteritis develop postinfection irritable bowel syndrome (PI-IBS) and postinfection functional dyspepsia (PI-FD), according to a review published online July 16 in Gut.Serena Porcari, M.D., from Università Cattolica del Sacro Cuore in Rome, and colleagues conducted a s

Dealing with chronic conditions like Crohn's disease and ulcerative colitis can be challenging and sometimes embarrassing. Inflammatory bowel disease (IBD) can cause diarrhea, stomach pain, weight loss and other symptoms. Also, the intersectionality of LGBTQ+ identity and having a chronic illness like IBD can sometimes make it difficult for patients to discuss their symptoms with health care profe

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

Dietary lipids play an essential role in regulating the function of the gut microbiota and gastrointestinal tract, and these luminal interactions contribute to mediating host metabolism.

For patients with cirrhosis and nonvalvular atrial fibrillation (AF), initiators of rivaroxaban or warfarin versus apixaban have significantly higher rates of major hemorrhage, according to a study published online July 9 in the Annals of Internal Medicine.Tracey G. Simon, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and co

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

For patients with refractory gastroesophageal reflux disease (GERD), those receiving antireflux mucosectomy (ARMS) have a greater improvement in the GERD questionnaire (GERDQ) score, according to a study published online June 12 in Surgical Endoscopy.Ah Young Lee, M.D., Ph.D., from Cha University in Seoul, South Korea, and colleagues

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

For patients with resectable pancreatic ductal adenocarcinoma (PDAC), the 12-month progression-free survival (PFS) may be increased with neoadjuvant modified 5-fluorouracil, leucovorin, oxaliplatin, and irinotecan (mFOLFIRINOX), according to a study published online June 20 in JAMA Oncology.Michael Cecchini, M.D., from the Yale Universi

Gastroesophageal reflux disease (GERD) is associated with an increased incidence of atrial fibrillation, according to a study published online June 2 in&nbsp;Frontiers in Cardiovascular Medicine.Lei Wang and Yi Wei Lu, from the Aerospace Center Hospital in Beijing, and colleagues assessed GERD’s role as a potential contributing factor i

Metabolic surgery is associated with significantly lower risk of major adverse cardiovascular events (MACE) compared with nonsurgical management among patients with moderate-to-severe obstructive sleep apnea (OSA) and obesity, according to a study published online June 21 in the Journal of the American College of Cardiology.Ali Aminian,

Remarkable new research by a University of Virginia undergraduate may help explain recurrent Crohn's disease in children and open the door to new ways to treat or even cure the devastating condition. The work is published in the journal Scientific Reports.

For children with eosinophilic esophagitis, dupilumab results in a significantly higher percentage of histologic remission, according to a study published in the June 27 issue of the New England Journal of Medicine.Mirna Chehade, M.D., M.P.H., from Icahn School of Medicine at Mount Sinai in New York City, and colleagues randomly assig

PIK3CA mutational status may be beneficial for predicting response to addition of the cyclooxygenase 2 (COX-2) inhibitor celecoxib to standard adjuvant chemotherapy in stage III resected colon cancer, according to a study published online June 18 in the Journal of Clinical Oncology.Jonathan A. Nowak, M.D., Ph.D., from Brigham

A new study led by researchers at UCL and the University of Sheffield, has demonstrated the potential of stem cell therapy to treat those with Hirschsprung disease.

A new study has illuminated the connection between inflammatory bowel disease (IBD) and lipid profile. IBD is a chronic condition that causes inflammation in the intestines. Abnormal lipid factor levels such as cholesterol in IBD patients have been observed in previous studies, but whether this association is causal remained unclear.

Benralizumab yields a greater histologic response than placebo for patients with eosinophilic esophagitis, but does not affect dysphagia symptoms, according to a study published in the June 27 issue of the New England Journal of Medicine.Marc E. Rothenberg, M.D., Ph.D., from the Leiden University Medical Center in the Netherlands, an

An international team of researchers has identified specific bacteria in the gut that are associated with both mice and humans developing an addiction to food that can lead to obesity. They have also identified bacteria that play a beneficial role in preventing food addiction.

Nutritionists generally advise everyone to eat more dietary fiber, but a new Cornell University study suggests that its effects on health can vary from person to person. The findings indicate that recommendations should be tailored to each individual's gut microbiome.

As industrialization and urbanization accelerate, noise-induced hearing loss (NIHL) has become an increasingly prevalent sensorineural hearing disorder. Despite the widespread use of hearing aids and cochlear implants to alleviate some of the challenges posed by hearing loss, these devices offer limited treatment efficacy and cannot reverse or cure damage to the auditory nerves and inner ear struc

Using just a single image taken by a capsule endoscopy camera, scientists have succeeded in creating a three-dimensional model of the colon. This new method provides much better images and can help specialists detect disease more rapidly.

The U.S. Food and Drug Administration has expanded the approval of Elevidys (delandistrogene moxeparvovec-rokl), a gene therapy for the treatment of Duchenne muscular dystrophy (DMD) in individuals ≥4 years with DMD with a confirmed mutation in the DMD gene.Elevidys is a single-dose, intravenous recombinant gene therapy designed to prod

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more. However, SCFA profiles can vary widely between individuals consuming the same exact diet and we currently lack tools for predicting this inter-individual variat

The cumulative risk for advanced gastric cancer varies from 6.5 to 10.3 percent for carriers of germline CDH1 pathogenic/likely pathogenic (P/LP) variants, according to a study published online June 14 in the Journal of the American Medical Association to coincide with presentation at the International Gastric Cancer Linkage Consortiu

In a study published in Science Translational Medicine, researchers at Imperial have found that a higher-fiber diet stimulates the release of a key appetite-reducing hormone, in the ileum, part of the small intestine.

Increasing physical activity during childhood may independently lower the risk for liver disease in young adulthood, according to a study published online May 29 in&nbsp;npj Gut and Liver.Andrew O. Agbaje, M.D., M.P.H., Ph.D., from the University of Eastern Finland in Kuopio, used data from 2,684 children (aged 11 years) participatin

Roux-en-Y gastric bypass (RYGB) is successful in achieving long-term sustained weight loss and diabetes remission, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.John Nguyen-Lee, M.D., from the Geisinger Medical Center in Danville, Pennsylva

The number of people severely sickened after consuming mushroom edibles sold as Diamond Shruumz-brand chocolate bars, cones or gummies has risen, the U.S. Food and Drug Administration said Tuesday."As of June 17, 2024, a total of 26 illnesses have been reported from 16 states," the FDA noted in an <a href="https://www.fda.gov/food/outbreaks-f

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

Combining antiobesity medications enhances preoperative weight loss in individuals with high body mass index (BMI) preparing for metabolic surgery, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.Michael Kachmar, D.O., from the Pennington Biome

Artificial intelligence (AI) has permeated many aspects of medicine, with promises of accurate diagnoses, better management decisions, and improved outcomes for both patients and the health care system. However, to successfully implement AI technology in clinical practice, trust and acceptance among health care providers to use such tools is crucial.

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

Most patients taking survodutide, a dual agonist of glucagon receptor and glucagon-like peptide-1 (GLP-1) receptor, experience significant improvement in metabolic dysfunction-associated steatohepatitis (MASH) without worsening of fibrosis, according to a phase 2 study published online June 7 in the&nbsp;New England Journal of Medicine&nbsp;to

Pantoprazole results in a significantly lower risk for clinically important upper gastrointestinal bleeding than placebo, with no increase in mortality, among patients undergoing invasive ventilation, according to a study published online June 14 in the New England Journal of Medicine to coincide with the annual Critical Care Reviews Meeting,

Bariatric surgery significantly decreases the conversion from prediabetes to type 2 diabetes, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.John Nguyen-Lee, M.D., from the Geisinger Medical Center in Danville, Pennsylvania, and colleagues eval

A medication used for psoriasis and psoriatic arthritis is proving to be an effective treatment for moderate to severe ulcerative colitis in the findings of a global study led by University of Chicago Medicine's David T. Rubin, MD, Professor of Medicine and Chief of the Section of Gastroenterology, Hepatology and Nutrition.

Recent technological advancements have enabled the development of new cutting-edge medical devices, including surgical robots, sensors that can monitor physiological processes and VR platforms to train doctors. A long-standing goal for medical technology engineers is to also create devices that can be ingested or otherwise inserted within the human body to observe or track the activity of specific

New research has shed light on the effects of protein-rich diets on the gut microbiome and overall health. Despite the increasing protein intake in Western diets, especially among athletes and individuals with obesity, the fate of undigested protein and its impact on human health remains largely unknown.

There is no evidence to suggest that administration of live vaccines to patients receiving dupilumab is unsafe, and vaccine efficacy is not affected by dupilumab, according to a position paper published online June 5 in the Annals of Allergy, Asthma &amp; Immunology.Noting that dupilumab targets the interleukin (IL)-4 receptor alpha sub

A new study, led by Professors Mashaghi and Clevers from Leiden University and Hubrecht Institute in the Netherlands, has introduced a novel approach using intestinal organoids to uncover the mechanism of gastrointestinal motility. The study presented the first single-cell mechanical characterization of human Enteroendocrine cells (EECs) isolated from healthy intestinal organoids.

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) for diabetes or obesity is associated with a lower quality of bowel preparation among patients undergoing colonoscopy, according to a study published online in the June issue of the American Journal of Gastroenterology.Rebecca Yao, M.D., M.P.H., from the Mayo Clinic in R

For patients with metabolic dysfunction-associated steatohepatitis (MASH) and moderate-to-severe fibrosis, 52 weeks of tirzepatide is more effective than placebo for resolution of MASH, according to a study published online June 8 in the New England Journal of Medicine to coincide with the annual congress of the European Association for the

The use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) for diabetes or obesity is associated with a lower quality of bowel preparation among patients undergoing colonoscopy, according to a study published in the June issue of the American Journal of Gastroenterology.

For patients with metabolic dysfunction-associated steatohepatitis (MASH) and moderate-to-severe fibrosis, 52 weeks of tirzepatide is more effective than placebo for resolution of MASH, according to a study published online June 8 in the New England Journal of Medicine to coincide with the annual congress of the European Association for the Study of the Liver, held from June 5 to 8 in Milan.

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications do slow gastric emptying but not by enough to warrant discontinuing medications before surgery, according to a review published in the June issue of the&nbsp;American Journal of Gastroenterology.Brent Hiramoto, M.D., from Brigham and Women's Hospital in Boston, and colle

Generation X is experiencing larger per-capita increases in the incidence of cancers than Baby Boomers, according to a study published online June 10 in JAMA Network Open.Philip S. Rosenberg, Ph.D., and Adalberto Miranda-Filho, Ph.D., from the National Cancer Institute in Bethesda, Maryland, estimated invasive cancer incidence trends

Significant progress has been made at Tufts University School of Engineering in the development of a small device, about the size of a vitamin pill, that can be swallowed and passed through the gastrointestinal tract to sample the full inventory of microorganisms in an individual's gastro-intestinal tract.

Scientists at the University of Southern California have developed an artificial intelligence (AI)-powered system to track tiny devices that monitor markers of disease in the gut. Devices using the novel system may help at-risk individuals monitor their gastrointestinal (GI) tract health at home, without the need for invasive tests in hospital settings. This work appears June 12 in the journal Cel

As described in research published in the Biotechnology Journal, investigators have developed a novel patch that can help liver tissue regenerate.

There is no significant association between exposure to immunosuppressive therapies and development of incident cancers among patients with inflammatory bowel disease (IBD) and a history of cancer, according to a study published online May 18 in Clinical Gastroenterology and Hepatology.Steven H. Itzkowitz, M.D., from the Icahn School o

A new proposed definition for Long COVID could help patients get the help they need, a new report from the National Academies of Sciences, Engineering and Medicine says.Long COVID is a chronic condition that occurs after COVID-19 infection and is present f

Bariatric metabolic surgery (BMS) is associated with a greater reduction in mortality than glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment among adults with a diabetes duration of 10 years or less, according to a study published online June 7 in JAMA Network Open.Dror Dicker, M.D., from Rabin Medical Center in Petah Tikva,

The combination of bulevirtide plus peginterferon alfa-2a is superior to bulevirtide monotherapy for achieving undetectable hepatitis D virus (HDV) RNA level at 24 weeks after the end of treatment in patients with chronic hepatitis D, according to a study published online June 6 in the&nbsp;New England Journal of Medicine to coincide with the

For adults with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), glucagon-like peptide 1 receptor agonists (GLP-1 RA) and sodium-glucose cotransporter 2 inhibitors (SGLT-2i) are associated with reduced risk of cardiovascular (CV) events compared with dipeptidyl peptidase 4 inhibitors (DPP-4i), according to a st

A team of Vanderbilt researchers has developed a wirelessly activated device that mimics the wavelike muscular function in the esophagus and small intestine responsible for transporting food and viscous fluids for digestion.

Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food. However, bile acids can become a double-edged sword. While they are necessary for proper digestion, high concentrations can also be toxic to the liver.

Neoadjuvant nivolumab plus ipilimumab has an acceptable safety profile in patients with locally advanced mismatch repair-deficient (dMMR) colon cancer, according to a study published in the June 6 issue of the New England Journal of Medicine.Myriam Chalabi, M.D., Ph.D., from the Netherlands Cancer Institute in Amsterdam, and colleague

Lowering the fecal immunochemical test (FIT) positive threshold yields levels of sensitivity and specificity that are comparable to those reported for multitarget stool RNA (mt-sRNA) testing without the additional testing, according to a research letter published online June 1 in the Journal of the American Medical Association.Tobias

Patients with gastric cancer who undergo gastrectomy have a lower risk for cardiovascular events than the general population, according to a study published online March 28 in the&nbsp;International Journal of Surgery.Yeongkeun Kwon, M.D., Ph.D.,&nbsp;from the Korea University College of Medicine in Seoul, and colleagues used data from

The popular prebiotic sodas known as Poppi may not be quite as good for the gut as the company claims.In a class-action lawsuit filed last week in U.S. District Court in San Francisco, Kristin Cobbs said she bought Poppi drinks because

Digestive Disease Week, the annual meeting sponsored by the American Association for the Study of Liver Diseases, American Gastroenterological Association, American Society for Gastrointestinal Endoscopy, and Society for Surgery of the Alimentary Tract, was held from May 18 to 21 in Washington, D.C., drawing more than 13,000 participants from around the world, including researchers and academics i

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the large intestine, also called the colon and rectum. At least 40,000 people are living with IBD in Ireland, and over 5 million globally.

Digestive Disease Week, the annual meeting sponsored by the American Association for the Study of Liver Diseases, American Gastroenterological Association, American Society for Gastrointestinal Endoscopy, and Society for Surgery of the Alimentary Tract, was held from May 18 to 21 in Washington, D.C., drawing more than 13,000 participants from around the world, in

For patients undergoing inguinal hernia surgery, emergency surgery rates increase from high- to low-income countries, according to a study published online May 23 in The Lancet Global Health.Maria Picciochi, Ph.D., from the University of Birmingham in the United Kingdom, and colleagues conducted a prospective, international, cohort study

Statin use may contribute to a significant reduction in the risk for new primary sclerosing cholangitis among patients with inflammatory bowel disease.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Nearly half of individuals diagnosed with early-onset colorectal cancer (EOCRC) present with hematochezia and abdominal pain and one-quarter present with altered bowel habits, according to a review published online May 24 in&nbsp;JAMA Network Open.Joshua Demb, Ph.D., from the University of California, San Diego, and colleagues examine

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

Continued weight loss with bariatric surgery was paralleled by favourable changes in eating behaviour and food reward and preferences.

For patients with chronic pancreatitis and intraductal stones, combined extracorporeal shock-wave lithotripsy (ESWL) and endoscopic retrograde pancreatography (ERP) provides pain relief at 12 weeks, according to a study published online May 28 in the Annals of Internal Medicine.Rupjyoti Talukdar, M.D., from the Asian Institute of Gastro

There are systemic disparities in definitive cancer treatment delivery at minority-serving hospitals (MSHs) versus non-MSHs, according to a study published online May 27 in Cancer.Edoardo Beatrici, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from the National Cancer Database for 2010 to 2019 to examine pa

It turns out flatulence can serve a purpose beyond being uncomfortable or funny: Gas released by some gut bacteria stimulates other gut bacteria to produce a hormone involved in pregnancy and in an FDA-approved treatment for postpartum depression, according to new research led by Harvard Medical School scientists.

Semaglutide was equally effective for obesity in patients with or without IBD, with a more than 5% mean weight loss and no increased risk for disease-specific adverse events.

Some are concerned that population screening could change symptomless people into patients, but a diagnosis could help prevent future complications.

Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver condition worldwide, affecting about 25% of the global population due to the increasing rates of obesity and metabolic syndrome. NAFLD encompasses a spectrum of liver conditions ranging from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH), which can progress to fibrosis, cirrhosis, and hepatocellul

Hepatocellular carcinoma (HCC) represents a significant global health burden as one of the most common malignancies in individuals with chronic liver disease or cirrhosis. This malignancy evolves through a multistep process, beginning with dysplastic nodules (DNs) and early HCC, progressing to overt HCC.

A U.S. Food and Drug Administration advisory panel on Thursday recommended the approval of a new blood test that can spot colon cancer.The panel voted 7-2 that the benefits outweigh the risks when using the Guardant Health's Shield test for&nbsp;colon cancer</a

Researchers looked at the interplay among sleep behaviors, genetic risks, and the development of 16 digestive diseases.

The researchers plan to do human clinical studies "as soon as possible."

In a clinical practice guideline issued by the American Gastroenterological Association and published online in the June issue of Gastroenterology, updated evidence-based recommendations are presented for the use of endoscopic eradication therapy (EET) in patients with Barrett esophagus (BE) and related neoplasia.Joel H. Rubenstein, M.

Patients with fibromyalgia and irritable bowel syndrome (IBS) have increased rates of severe multiple drug intolerance syndrome (MDIS), according to a study published in the May issue of the Journal of Allergy and Clinical Immunology: In Practice.Alicia A. Alvarez, M.D., from Sarasota Memorial Hospital in Florida, and colleagues conduc

In the realm of gastrointestinal (GI) endoscopy, artificial intelligence (AI) is becoming an essential tool, especially in the computer-aided detection of precancerous colon polyps during screening colonoscopy. This integration marks a significant advancement in gastroenterology care. However, the inevitability of errors persists, and in some cases, AI algorithms themselves could contribute to med

Sleeve gastrectomy leads to significant weight loss and improves eligibility for kidney transplant in adults with obesity and severe kidney disease.

An AI-based assessment before colonoscopy successfully identified individuals at high risk for missed adenomas due to inadequate bowel preparation.

After a 2023 study linked GLP-1s to an increased risk for pancreatitis, gastroparesis, and bowel obstruction, other researchers did a retrospective study to reexamine the association.

A study of 316,443 patients shows that 7.4% of these patients repeated fecal testing rather than proceeding directly to colonoscopy as guidelines recommend, and of those who repeated home tests, over half did not have a colonoscopy within 1 year.

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

The monoclonal antibody in development as maintenance therapy for people with moderately to severely active ulcerative colitis was more effective than placebo.

Meaningful weight loss was seen with the use of semaglutide, regardless of whether people had previous weight loss surgery, a first-of-its-kind study revealed.

For adults who are not up to date with colorectal cancer screening, offering a choice of colonoscopy or fecal immunochemical testing (FIT) increases screening completion rates, according to a study published online April 30 in Clinical Gastroenterology and Hepatology.Shivan J. Mehta, M.D., from the Perelman School of Medicine at the Uni

With an assist from machine learning, investigators find a genetic test that can identify obesity phenotypes and predict who will benefit most from semaglutide for weight loss.

Dietary interventions could be considered as an initial treatment for patients with IBS, although more research is needed for personalized treatment plans.

Patients with complicated diverticulitis or who aren't current with colorectal cancer screening are at higher risk and should have follow-up colonoscopy to rule it out.

GI endoscopy generates 85,000 metric tons of carbon dioxide waste annually. That waste stems from high case volumes, patient travel, the decontamination process, and single-use devices.

Already approved for ulcerative colitis, the monoclonal antibody mirikizumab met study endpoints for Crohn's disease response and remission.

The addictive behavior underlying many cases of ALD often goes unaddressed. Experts offer their advice on how gastroenterologists can begin to change this in their practices.

The AGA has released updated evidence-based recommendations on the EET of Barrett's esophagus and related neoplasms, in which experts call for an individualized approach.

Patients seen by a female gastroenterologist for an initial consultation are less likely to use medical care in the emergency department, hospital or primary care office for two years after their visit when compared to patients initially seen by male gastroenterologists, according to a study presented at Digestive Disease Week (DDW) 2024, held May 18–21, in Washington, D.C.