All articles tagged: Pharmacy

An estimated 6.7 percent of U.S. adults cannot use popular automatic blood pressure devices due to arm circumference, according to a research letter published online Sept. 5 in Hypertension to coincide with the American Heart Association Hypertension 2024 Scientific Sessions, held from Sept. 5 to 8 in Chicago.Eileen Kaur, from

Immunotherapy (IO) utilization is increasing over time, but significant socioeconomic disparities exist for patients with advanced clear cell renal cell carcinoma (ccRCC) and urothelial carcinoma of the bladder (UC), according to a study published in the November issue of Urologic Oncology: Seminars and Original Investigations.Levi Holl

Machine learning can identify patients who are at risk for persistent opioid use after surgery, according to a study published in the September issue of Plastic and Reconstructive Surgery.Natalie B. Baxter, from the University of Michigan Medical School in Ann Arbor, and colleagues trained two algorithms to predict persistent opioid use

Adjunctive treatment with intravenous argatroban or eptifibatide does not reduce poststroke disability among patients with acute ischemic stroke treated with intravenous thrombolysis within three hours after symptom onset, according to a study published in the Sept. 5 issue of the New England Journal of Medicine.Opeolu Adeoye, M.D., fro

Girls with mental illness and neurodevelopmental conditions have lower uptake of human papillomavirus (HPV) vaccination, according to a study published in the September issue of The Lancet Public Health.Kejia Hu, Ph.D., from the Karolinska Institutet in Stockholm, and colleagues conducted a population-based cohort study to examine the

For patients with metastatic or surgically unresectable leiomyosarcoma, combination therapy with doxorubicin and trabectedin is associated with improved overall and progression-free survival compared with doxorubicin alone, according to a study published online Sept. 4 in the New England Journal of Medicine.Patricia Pautier, M.D., fro

For older adults, respiratory syncytial virus (RSV) vaccination is effective against RSV hospitalization, according to a study published online Sept. 4 in the Journal of the American Medical Association.Diya Surie, M.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues examined RSV vaccine effectiven

About 3.5 percent of older adults do not take prescription medications due to cost and a similar percentage do not take medications as prescribed due to cost, according to a study published online Sept. 5 in the National Health Statistics Reports, a publication from the National Center for Health Statistics.Robin A. Cohen, Ph.D.,

The maker of the ADHD drug Vyvanse has been given approval by the U.S. Drug Enforcement Administration to make more of the medication as a shortage of the critical drugs continues.Following a request from the U.S. Food and Drug Administration in July, the DE

The humanized monoclonal antibody directed against the pituitary adenylate cyclase-activating polypeptide (PACAP) ligand, Lu AG09222, is better than placebo for reducing migraine frequency over four weeks, according to a study published in the Sept. 5 issue of the New England Journal of Medicine.Messoud Ashina, M.D., from Copenhagen

First-generation antihistamines are associated with a higher seizure risk in young children, according to a study published online Aug. 28 in JAMA Network Open.Ju Hee Kim, M.D., from the Kyung Hee University Medical Center in Seoul, South Korea, and colleagues evaluated associations between prescriptions of first-generation anti

Inhaler devices are a substantial source of greenhouse gas emissions in the United States, according to a research letter published online Aug. 29 in the Journal of the American Medical Association.Jyothi Tirumalasetty, M.D., from the Stanford University School of Medicine in California, and colleagues assessed mean emissions in

Time from approval to reimbursement of new drugs varies between countries and is shortest in Switzerland and Germany, both of which include health technology assessment decisions that are not used in the United States, according to a study published online Sept. 3 in the Annals of Internal Medicine.Camille E.G. Glaus, J.D., from the Un

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors may prevent dementia in middle-aged adults with diabetes, according to a study published online Aug. 28 in The BMJ.Anna Shin, from Seoul National University Bundang Hospital in South Korea, and colleagues compared the risk for dementia associated with SGLT-2 inhibitors versus dipe

Postmenopausal women who use hormone therapy (HT) are biologically younger than those not receiving HT, according to a study published online Aug. 29 in JAMA Network Open.Yufan Liu and Chenglong Li, Ph.D., from Peking University in Beijing, evaluated the association between HT use and discrepancies between chronological and biolog

Home administration of misoprostol significantly increases the proportion of day-care procedures in medical abortion after 12 gestational weeks, according to a study published in the Aug. 31 issue of The Lancet.Johanna Rydelius, M.D., from the University of Gothenburg in Sweden, and colleagues evaluated whether administering the first m

Dietary intake of vitamin E may potentially lower the risk for atopic dermatitis, according to a study published online Aug. 9 in Skin Research & Technology.Siqing Wang, from the Beijing University of Chinese Medicine, and colleagues conducted a Mendelian randomization analysis to explore the causal relationship between dietary

Regardless of drug use, administration of naloxone during out-of-hospital cardiac arrest (OHCA) is associated with improved outcomes, such as increased survival to hospital discharge, according to a study published online Aug. 20 in JAMA Network Open.David G. Dillon, M.D., Ph.D., from the University of California, Davis, and coll

Patients with post-COVID-19 mRNA vaccination myocarditis show a lower frequency of cardiovascular complications than those with conventional myocarditis or post-COVID-19 myocarditis at 18 months, according to a study published online Aug. 26 in the Journal of the American Medical Association.Laura Semenzato, from the French Natio

People with self-identified xylazine wounds are more likely to engage in subcutaneous injection and face several barriers to seeking medical wound treatment, according to a study published online Aug. 21 in Drug and Alcohol Dependence.Raagini Jawa, from the University of Pittsburgh School of Medicine, and colleagues sought to und

For adults experiencing migraine attacks with moderate-to-severe headache pain, ubrogepant administered during prodrome is beneficial for patient-reported outcomes, according to a study published online Aug. 28 in Neurology.Richard B. Lipton, M.D., from the Albert Einstein College of Medicine in Bronx, New York, and colleagues conduc

Adult patients with inflammatory bowel disease (IBD) and respiratory syncytial virus (RSV) infection have an increased risk for hospitalization, according to a study published online in the August issue of The American Journal of Gastroenterology.Ryan A. Smith, M.D., from University of Wisconsin in Madison, and colleagu

Patients treated with high-dose psilocybin have better responses than those treated with placebo in antidepressant trials, according to a study published online Aug. 21 in The BMJ.Tien-Wei Hsu, M.D., from E-DA Dachang Hospital in Kaohsiung, Taiwan, and colleagues examined the comparative effectiveness and acceptability of oral monoth

Cholinesterase inhibitors (ChEIs) are beneficial for patients with dementia with Lewy bodies (DLB), according to a study published online Aug. 23 in Alzheimer's & Dementia.Hong Xu, M.D., Ph.D., from the Center for Alzheimer Research at the Karolinska Institutet in Stockholm, and colleagues examined the impact of ChEIs and memanti

For adults with kidney stones, increasing thiazide dose is associated with greater reductions in calcium, which are negatively associated with symptomatic stone events, according to a research letter published online Aug. 22 in JAMA Network Open.Ryan S. Hsi, M.D., from the Vanderbilt University Medical Center in Nashville, Tennessee,

Semaglutide reduces the risk for major adverse cardiovascular events (MACE) and composite heart failure end points compared with placebo in patients with overweight or obesity and heart failure, according to a study published online Aug. 24 in The Lancet.John Deanfield, B.Chir., M.B., from the Institute of Cardiovascular Sciences at

Counties with high pharmacy desert densities also face social vulnerability and health care provider shortages, according to a research letter published online Aug. 23 in JAMA Network Open.Giovanni Catalano, M.D., from The Ohio State University Wexner Medical Center in Columbus, and colleagues examined if pharmacy deserts dispropo

On Monday, the U.S. Food and Drug Administration approved the Insulet Omnipod 5 insulin delivery system for patients with type 2 diabetes. It is the first such system for use by people with the more prevalent form of the disease.The FDA first signed off on the system, which automatically adjusts insulin delivery as needed, for type 1 diabetes i

In middle-aged individuals with Down syndrome (DS), lecanemab-labeled amyloid plaques are seen in postmortem brain tissue analysis, in addition to extensive binding to brain blood vessels, according to a study published online Aug. 19 in JAMA Neurology.Lei Liu, M.D., Ph.D., from Brigham and Women's Hospital in Boston, and colleagues ex

For menopausal vasomotor symptoms (VMS), elinzanetant is efficacious and well-tolerated, according to a study published online Aug. 22 in the Journal of the American Medical Association.JoAnn V. Pinkerton, M.D., from the University of Virginia Health in Charlottesville, and colleagues examined the efficacy and safety of elinzanetant, a

Eli Lilly, maker of one of the blockbuster GLP-1 weight-loss drug Zepbound, says it will now offer the medication in single-dose vials at half the price currently available to consumers.The new 2.5 milligram (mg) and 5 mg weekly dose vials differ from the standard preloaded injector pens that are used to administer Zepbound (tirzepatide) and co

As an mpox outbreak continues to rage in Africa, the World Health Organization on Monday launched a six-month plan to quell its spread.“The mpox outbreaks in the Democratic Republic of the Congo and neighboring countries can be controlled, and can be stopped,” WHO Director-General <a href="https://blogs.worldbank.org/en/team/t/tedros-adhanom-gh

Increases in eligibility for semaglutide are discussed in a research letter published online Aug. 27 in the Annals of Internal Medicine.After the Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity trial showed that semaglutide reduced cardiovascular events in certain patients without diabetes, Medicar

For older adults with type 2 diabetes, the risk for dementia seems similar with sodium-glucose cotransporter 2 (SGLT2) inhibitors and the glucagon-like peptide 1 receptor agonist (GLP-1 RA) dulaglutide, according to a study published online Aug. 27 in the Annals of Internal Medicine.Bin Hong, from the School of Pharmacy at Sungkyunkwan

More than three in four people (77 percent) say they would not know how to respond if they saw someone having an opioid overdose, according to survey results from The Ohio State University."While I'm not surprised about this result, I am deeply concerned because we know that the more of us who are prepared to save a life, the more lives we can s

In 2023, vaccination coverage for adolescents with all routine vaccines was similar to coverage in 2022, according to research published in the Aug. 22 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Cassandra Pingali, M.P.H., from the CDC in Atlanta, and colleagues analyzed data from t

For men with high-risk biochemically recurrent prostate cancer, olaparib monotherapy yields good prostate-specific antigen (PSA) response rates, especially among those with BRCA2, according to a study published online Aug. 22 in JAMA Oncology.Catherine H. Marshall, M.D., from the Johns Hopkins University School of Medicine in B

As a summer surge in COVID cases begins to ebb and Americans brace themselves for yet another wave of infections this winter, more free COVID tests will soon be available to all, federal health officials announced Friday.Starting in late September, every U.S. household can order up to four nasal swab tests when the federal program reopens, accor

The prevalence of diabetes increased in the United States from 2012 to 2022, according to a research letter published online July 18 in&nbsp;Diabetes, Obesity and Metabolism.Sulakshan Neupane, from the University of Georgia in Athens, and colleagues examined recent national trends and disparities in self-reported diabetes prevalence amo

Restricted buprenorphine dispensing was most pronounced in socially and economically disadvantaged communities, according to a study published in the September issue of&nbsp;Drug and Alcohol Dependence Reports.Kyle J. Moon, from the Johns Hopkins Bloomberg School of Public Health in Baltimore, and colleagues conducted a U.S. telephone a

Belzutifan, a hypoxia-inducible factor 2α (HIF-2α) inhibitor, improves progression-free survival and objective responses over everolimus among patients with advanced clear-cell renal cell carcinoma, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.Toni K. Choueiri, M.D., from the Dana-Farber Can

Updated shots to shield against COVID-19 infection were approved by the U.S. Food and Drug Administration on Thursday.This year's approval for the updated mRNA vaccines comes much sooner than happened in 2023, when fall vaccines were authorized on Sept. 1

Semaglutide-associated suicidal ideation has been identified in a disproportionality analysis, according to a study published online Aug. 20 in JAMA Network Open.Georgios Schoretsanitis, M.D., Ph.D., from Northwell Health in Glen Oaks, New York, and colleagues examined potential signals for suicidal and self-injurious adverse drug re

Updated COVID-19 vaccines may receive approval from the U.S. Food and Drug Administration this week.Two sources familiar with the issue told CNN that updated mRNA vaccines from Moderna and Pfizer that target the KP.2 variant could be greenlit as early as this week. The news agency said the sources declined to be named because informati

For patients with hepatocellular carcinoma (HCC), immune checkpoint inhibitor (ICI) use prior to liver transplant (LT) does not worsen outcomes, according to research published online July 10 in the Journal of Hepatology.Mohammad Saeid Rezaee-Zavareh, from the Middle East Liver Diseases Center in Tehran, Iran, and colleagues summarized

Women with epilepsy have a considerably higher risk for severe maternal and perinatal outcomes and an increased risk for death during pregnancy and postpartum, according to a study published online Aug. 5 in&nbsp;JAMA Neurology.Neda Razaz, Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined associations between m

The U.S. Food and Drug Administration has approved Nemluvio (nemolizumab) for adult patients living with prurigo nodularis.Nemluvio, administered as a prefilled pen for subcutaneous injection, inhibits interleukin-31 cytokine signaling, which is known to drive itch and is involved in inflammation, altered epidermal differentiation, and fibrosi

Medications for attention-deficit/hyperactivity disorder (ADHD) are effective at improving quality of life in people with the disorder, according to a review recently published in the&nbsp;Journal of the American Academy of Child &amp; Adolescent Psychiatry.Alessio Bellato, Ph.D., from the University of Southampton in the United Kingd

For individuals with chronic noncancer pain (CNCP) treated with opioid analgesics, problematic pharmaceutical opioid use (POU) is common, according to a study published online Aug. 7 in Addiction.Kyla H. Thomas, Ph.D., M.B.B.S., from the University of Bristol in the United Kingdom, and colleagues conducted a comprehensive systematic l

The Biden administration said Thursday that it has signed deals with drug companies that will lower the prices on 10 of the most popular and expensive drugs used by American seniors.Taxpayers should save $6 billion because of the new prices, while seniors using Medicare could save roughly $1.5 billion on their medications, the U.S. Centers for

The Vaccines for Children (VFC) program, which provides recommended vaccines at no cost to eligible children, has increased childhood vaccination coverage, but coverage is still lower than among non-VFC-eligible children, according to a Vital Signs report published Aug. 13 in the U.S. Centers for Disease Control and Prevention Morbidity

For most patients with multiple sclerosis (MS), there is no increased risk for relapse after COVID-19 vaccination, according to a study published online Aug. 14 in Neurology.Xavier Moisset, M.D., Ph.D., from the Universite Clermont Auvergne in Clermont-Ferrand, France, and colleagues conducted a nationwide study using data from the F

Among U.S. adults with diabetes, cannabis use in the past month increased by 33.7 percent from 2021 to 2022, according to a research letter published online July 22 in Diabetes Care.Benjamin H. Han, M.D., M.P.H., from the University of California, San Diego, School of Medicine in La Jolla, and colleagues estimated the most recent nat

Fish oil seems to counteract genetic predisposition to high cholesterol, according to a study published online July 15 in the&nbsp;American Journal of Clinical Nutrition.Yitang Sun, Ph.D., from the Franklin College of Arts and Sciences at the University of Georgia in Athens, and colleagues examined whether fish oil supplementation mo

For patients with advanced endometrial cancer (EC), sacituzumab govitecan (SG), a trophoblast cell-surface antigen 2 (Trop-2)-directed antibody-drug conjugate, shows encouraging efficacy, according to a phase 2 study published online July 31 in the Journal of Clinical Oncology.Alessandro D. Santin, M.D., from the Yale School of Medic

Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with lower rates of hyperkalemia and a lower rate of renin-angiotensin system inhibitor (RASi) discontinuation compared with treatment with dipeptidyl peptidase-4 inhibitors (DPP-4is) among patients with type 2 diabetes (T2D), according to a study published online Aug. 1

Pregnancies exposed to buprenorphine combined with naloxone have similar or more favorable neonatal and maternal outcomes as those exposed to buprenorphine alone, according to a study published online Aug. 12 in the Journal of the American Medical Association.Loreen Straub, M.D., from Brigham and Women's Hospital and Harvard Medical Sch

For patients with type 2 diabetes, treatment with tirzepatide (a dual glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptor agonist) is associated with lower risks for all-cause mortality and adverse cardiovascular and kidney events compared with glucagon-like peptide 1 receptor agonist treatment (GLP-1 RA), according to a s

For patients with atopic dermatitis (AD), dupilumab maintains its clinical effectiveness up to five years and is discontinued by 23.8 percent of patients, according to a study published online Aug. 7 in JAMA Dermatology.Celeste M. Boesjes, M.D., from the University Medical Center Utrecht in the Netherlands, and colleagues examined clini

A gene expression signature in peripheral CD4+ T-cells can predict severe immune-related adverse events (irAEs) among melanoma patients treated with ipilimumab/nivolumab, according to a study published online Aug. 8 in Clinical Cancer Research.Kelsey R. Monson, Ph.D., from the Perlmutter Cancer Center at NYU Langone Health in

Sulfonamide antibiotics and cephalosporins are most strongly associated with serious cutaneous adverse drug reactions (cADRs), according to a study published online Aug. 8 in the Journal of the American Medical Association.Erika Y. Lee, M.D., from the University of Toronto, and colleagues explored the risk for serious cADRs associated w

Advocates for the use of the psychedelic drug MDMA (midomafetamine) to treat mental health conditions were delivered a setback on Friday after the U.S. Food and Drug Administration declined to approve it as treatment for post-traumatic stress disorder (PTSD).There is insufficient evidence that MDMA -- currently illegal and also known as Ecstasy

The U.S. Food and Drug Administration has approved Voranigo (vorasidenib) for grade 2 astrocytoma or oligodendroglioma with a susceptible mutation.The isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor is approved for adult and pediatric patients ages 12 years and older with grade 2 astrocytoma or oligodendroglioma

Childhood vaccinations continue to provide substantial health and economic benefits, according to research published in the Aug. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Noting that the U.S. Vaccines for Children (VFC) program has covered the cost of vaccines for children whose

In two practice recommendations published in the Aug. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report, updated recommendations are presented relating to use of specific contraceptive methods and for persons with certain characteristics or medical conditions.Kathryn M. Curtis, Ph.D., fr

Long-acting injectable cabotegravir (CAB-LA) appears to be well tolerated in pregnant women, according to a study presented at AIDS 2024, the 25th International AIDS Conference, held from July 22 to 26 in Munich.Sinead Delany-Moretlwe, M.B.B.Ch., Ph.D., from the University of the Witwatersrand in South Africa, and colleagues reported on materna

For patients with HIV in the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) trial, use of abacavir was associated with an increased incidence of major adverse cardiovascular events (MACE), according to a study presented at AIDS 2024, the 25th International AIDS Conference, held from July 22 to 26 in Munich.Carl J. Fichtenbaum, M.

Interprofessional addiction consultation services significantly increase postdischarge medication for opioid use disorder (MOUD) initiation and engagement among patients with opioid use disorder, according to a study published online July 29 in&nbsp;JAMA Internal Medicine.Jennifer McNeely, M.D., from New York University Grossman School

For pregnancies at high risk for early-onset severe hemolytic disease of the fetus and newborn (HDFN), intravenous nipocalimab can delay or prevent fetal anemia or intrauterine transfusions, according to a study published online Aug. 7 in the New England Journal of Medicine.Kenneth J. Moise Jr., M.D., from Dell Medical School at the U

The U.S. Food and Drug Administration has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj) in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation in patients with newly diagnosed multiple myeloma (MM) who are eligible for an autologous stem cell transplant (ASCT).The approval was ba

For pediatric patients with acute myeloid leukemia (AML), a pharmacogenomics-based 10 single nucleotide polymorphism cytarabine (Ara-C) score (ACS10) can be used to tailor induction regimens, yielding improved outcomes, according to a study published online July 30 in Clinical Cancer Research.Noting that low ACS10 has been shown to be

U.S. adults lost trust in physicians and hospitals during the COVID-19 pandemic, according to a study published online July 31 in&nbsp;JAMA Network Open.Roy H. Perlis, M.D., from Massachusetts General Hospital in Boston, and colleagues examined how trust in physicians and hospitals changed during the COVID-19 pandemic. The analysis incl

The U.S. Food and Drug Administration has approved Tecelra (afamitresgene autoleucel), a gene therapy for the treatment of adults with unresectable or metastatic synovial sarcoma.Specifically, the approval is for adults who have received prior chemotherapy, are HLA-A*02:01P, -A*02:02P, -A*02:03P, or -A*02:06P positive, and have a tumor that expr

Aspirin use is associated with a reduction in colorectal cancer (CRC) risk, with the greatest reduction seen among those with the unhealthiest lifestyle scores, according to a study published online Aug. 1 in JAMA Oncology.Daniel R. Sikavi, M.D., from Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues ex

An estimated 15 million U.S. adults consumed at least one of six potentially hepatotoxic botanicals within the previous 30 days, according to a study published online Aug. 5 in JAMA Network Open.Alisa Likhitsup, M.D., M.P.H., from the University of Michigan in Ann Arbor, and colleagues assessed the prevalence and clinical characteristics

From 2021 through 2023, there was a considerable increase in the number of semaglutide fills, according to a research letter published online Aug. 2 in JAMA Health Forum.Christopher Scannell, M.D., Ph.D., from the University of Southern California in Los Angeles, and colleagues analyzed trends in prescriptions dispensed at retail pharmac

For patients with alcohol use disorder (AUD) treated with antidepressants, those who achieve a reduction in depression symptoms have fewer relapses over time, according to a study published online July 26 in Alcohol: Clinical &amp; Experimental Research.Joshua Jaeger, from the University of Bern in Switzerland, and colleagues examined th

Direct oral anticoagulant (DOAC) prescribing oversight for off-label prescribing is beneficial while patients are prescribed DOAC, according to a study published online July 30 in Thrombosis and Haemostasis.Grace C. Herron, from the Frankel Cardiovascular Center at the University of Michigan in Ann Arbor, and colleagues evaluated data fr

Recently, there was an increase in availability of naloxone after it was approved to be sold as an over-the-counter (OTC) medication, according to a study published online July 26 in JAMA Health Forum.Grace T. Marley, Pharm.D., from the UNC Eshelman School of Pharmacy in Chapel Hill, North Carolina, and colleagues examined whether the ac

The U.S. Food and Drug Administration has approved Leqselvi (deuruxolitinib) tablets for the treatment of adults with severe alopecia areata.Leqselvi (8 mg) is a twice-daily oral selective inhibitor of the Janus kinases JAK1 and JAK2. In trials, the three most common adverse events were headache, acne, and nasopharyngitis.The approval was

Semaglutide products are being sold online, with products likely unregistered or unlicensed, according to a research letter published online Aug. 2 in JAMA Network Open.Amir Reza Ashraf, Pharm.D., from the University of Pécs in Hungary, and colleagues conducted a risk assessment of semaglutide online sourcing. Websites advertising semagl

Community pharmacists can play an effective role in closing gaps in the delivery of stroke risk reduction therapy by prescribing appropriate oral anticoagulation therapy (OAC) for high-risk older individuals with atrial fibrillation (AF), according to a study published online July 24 in&nbsp;JAMA Network Open.Roopinder K. Sandhu, M.D.

COVID-19 vaccination seems to have some side effects on the lower urinary tract and overactive bladder in younger adults, according to a study published online June 24 in Frontiers in Medicine.Marta de-la-Plaza-San-Frutos, from Universidad Europea de Madrid in Spain, and colleagues examined potential side effects of COVID-19 vaccinatio

The use of cholesterol absorption inhibitors is associated with a reduced risk for liver cancer, according to a study published online July 29 in&nbsp;Cancer.Shahriar A. Zamani, Ph.D., from the National Cancer Institute at the National Institutes of Health in Rockville, Maryland, and colleagues examined the risk for liver cancer for

For patients with knee osteoarthritis (KOA), methotrexate added to usual medication is associated with a significant reduction in pain and improvement in stiffness and function at six months, according to a study published online July 30 in the Annals of Internal Medicine.Sarah R. Kingsbury, Ph.D., from the University of Leeds in the

New-onset cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are rare beyond two weeks following infusion of CD19-directed chimeric antigen receptor T (CAR T)-cell therapies, according to a study published online July 23 in Blood Advances.Noting that the U.S. Food and Drug Administration

Overall, 16.2 percent of opioid-naive youths undergoing a surgical procedure filled an initial opioid prescription one to 14 days before surgery, according to a study published online July 5 in JAMA Network Open.Tori N. Sutherland, M.D., M.P.H., from the Children's Hospital of Philadelphia, and colleagues characterized changes in preop

Use of nasal sprays and a behavioral intervention promoting physical activity and stress management can reduce antibiotic use for respiratory illness, according to a study published online July 11 in The Lancet Respiratory Medicine.Paul Little, M.B.B.S., M.D., from the University of Southampton in the United Kingdom, and colleagues exa

Once-daily TAS-303 is superior to placebo for treatment of stress urinary incontinence (SUI) in women, according to a study published in the August issue of The Journal of Urology.Satoru Takahashi, M.D., Ph.D., from Nihon University School of Medicine in Tokyo, and colleagues conducted a double-blind phase 2 study involving women with

People taking compounded versions of Ozempic have been overdosing on the drug, the U.S. Food and Drug Administration warns.These ODs typically are due to miscommunications or miscalculations regarding dosage, the FDA added.“Dosing errors have res

For patients with type 2 diabetes mellitus (T2DM) and tobacco use disorder (TUD), new use of semaglutide is associated with lower risk of TUD-related health care measures compared with other antidiabetes medications, according to a study published online July 30 in the Annals of Internal Medicine.William Wang, from the Case Western Rese

For adult patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) who have measurable residual disease (MRD)-negative remission, blinatumomab in addition to consolidation chemotherapy is associated with improved overall survival, according to a study published in the July 25 issue of the New England Journal of Medicine.Mar

In a research letter published online July 24 in the New England Journal of Medicine, the authors describe long-acting early viral inhibition (LEVI) among patients with acute HIV infection in the context of long-acting injectable cabotegravir (CAB-LA) preexposure prophylaxis (PrEP). The research was published to coincide with the 25th Internat

Hydroxychloroquine appears to be a safe and effective treatment option for anogenital lichen sclerosus that only has mild adverse effects, according to a study published online July 19 in the&nbsp;International Journal of Dermatology.Christeebella O. Akpala, from the Mayo Clinic in Rochester, Minnesota, and colleagues analyzed the demog

Abbott has warned diabetes patients that some of its continuous blood sugar monitoring systems may need to be replaced because of inaccurate readings."Abbott has recently identified a small number of FreeStyle Libre 3 sensors that may provide incorrect high glucose readings, which if undetected may pose a potential health risk for people living

The rate at which young Americans are ending up in hospital ICUs after using fake Oxycontin pills spiked with fentanyl is soaring, especially in the U.S. West, a new report warns.Medical toxicology data from one unnamed hospital in the western U.S. found the number of cases involving overdoses involving fake "M-30" Oxycontin pills rose from just

U.S adolescents reported declines in medical use and nonmedical use (NMU) of prescription stimulants, opioids, and benzodiazepines from 2009 to 2022, according to a research letter published online July 24 in the Journal of the American Medical Association.Sean Esteban McCabe, Ph.D., from the University of Michigan School of Nursing i

For girls and young women with sickle cell disease (SCD), exposure to hydroxyurea does not reduce ovarian reserve, according to a study published online July 18 in Blood Advances.Tamara Diesch-Furlanetto, Ph.D., from the University of Basel Children's Hospital in Switzerland, and colleagues counted follicles and categorized them based

Lack of institutional support is the most common reason for physicians to have reluctance to address substance use and addiction in their clinical practices, according to a review published online July 17 in&nbsp;JAMA Network Open.Melinda Campopiano von Klimo, M.D., from JBS International Inc. in North Bethesda, Maryland, and colleag

Use of oral corticosteroids for &gt;90 days during one year is associated with a slightly increased risk of adverse events (AEs), according to a study published online July 19 in&nbsp;JAMA Network Open.Yong Hyun Jang, M.D., Ph.D., from Kyungpook National University in Daegu, South Korea, and colleagues examined the association betwee

The prevalence of impaired awareness of hypoglycemia (IAH) is high among patients using sulfonylureas long term, according to a study published in the July/August issue of the&nbsp;Annals of Family Medicine.Hsiang-Ju Cheng, M.D., from the National Cheng Kung University in Tainan, Taiwan, and colleagues investigated the relationship bet

For patients with atrial fibrillation, digoxin and beta-blockers have equivalent effects on heart rate at rest and on exertion, according to a study published online July 15 in Nature Medicine.Simrat K. Gill, from the University of Birmingham in the United Kingdom, and colleagues compared heart rate in older, multimorbid patients with

The cumulative incidence of postacute sequelae of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection (PASC) during the first year after infection decreased over the course of the pandemic, according to a study published online July 17 in the&nbsp;New England Journal of Medicine.Yan Xie, Ph.D., from the Veterans Affa

From 2011 to 2023, there was an increase in new glucagon like peptide 1 receptor agonist (GLP-1RA) prescriptions, according to a research letter published online July 23 in the Annals of Internal Medicine.Yee Hui Yeo, M.D., from Cedars-Sinai Medical Center in Los Angeles, and colleagues examined nationwide trends in GLP-1RA prescription

For older nursing home (NH) residents, use of CYP2D6-metabolized opioids concomitantly with CYP2D6-inhibiting antidepressants is associated with worsening pain and increased risk of opioid-related adverse events (ORAEs), according to a study published online July 23 in the Annals of Internal Medicine.Yu-Jung Jenny Wei, Ph.D., from the C

Neuromuscular training reduces the onset of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online July 1 in JAMA Internal Medicine.Fiona Streckmann, Ph.D., from the University of Basel in Switzerland, and colleagues examined whether sensorimotor training (SMT) and whole-body vibration (WBV) training re

For children with severe hemophilia A, once-weekly prophylaxis with efanesoctocog alfa is associated with high sustained factor VIII activity, resulting in effective prevention of bleeding, according to a study published in the July 18 issue of the New England Journal of Medicine.Lynn Malec, M.D., from the Versiti Blood Research Institu

Oral micronutrient supplementation slows geographic atrophy (GA) progression in age-related macular degeneration (AMD), according to a study published online July 16 in Ophthalmology.Tiarnan D.L. Keenan, B.M., B.Ch., Ph.D., from the National Institutes of Health in Bethesda, Maryland, and colleagues examined whether oral supplements slo

COVID-19 infection and vaccination during the first trimester of pregnancy are not associated with congenital anomalies, according to a study published online July 17 in The BMJ.Maria C. Magnus, Ph.D., from the Norwegian Institute of Public Health in Oslo, and colleagues conducted a prospective cohort study of 343,066 live-born singleto

Postexposure prophylaxis with nirmatrelvir-ritonavir for five or 10 days does not reduce the risk for symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published in the July 18 issue of the New England Journal of Medicine.Jennifer Hammond, Ph.D., from Pfizer in Collegeville, Penns

For patients with moderate-to-severe Crohn disease, risankizumab is noninferior to ustekinumab for clinical remission at week 24 and is superior for endoscopic remission at week 48, according to a study published in the July 18 issue of the New England Journal of Medicine.Laurent Peyrin-Biroulet, M.D., Ph.D., from the INFINY Institut

For patients with relapsing multiple sclerosis (RMS), ofatumumab is more effective than teriflunomide across racial and ethnic subgroups, according to a study published online July 17 in Neurology.Mitzi J. Williams, M.D., from the Joi Life Wellness MS Center in Atlanta, and colleagues conducted a post-hoc analysis to compare the prop

For patients with treatment-resistant depression, racemic ketamine, given as an extended-release tablet (R-107), administered orally, is effective, safe, and well tolerated, according to a study published online June 24 in Nature Medicine.Paul Glue, M.D., from the University of Otago in Dunedin, New Zealand, and colleagues examined t

As people with diabetes age into Medicare, they face increased quarterly out-of-pocket costs for medication, according to a study published online July 9 in&nbsp;JAMA Network Open.Douglas Barthold, Ph.D., from the University of Washington in Seattle, and colleagues examined whether reaching age 65 years is associated with changes in

For patients experiencing migraine, direct calcitonin gene-related peptide (CGRP) inhibition with monoclonal antibodies (mAbs) is associated with reduced rates of acne and rosacea compared with no inhibition (topiramate) or indirect inhibition (triptans), according to a research letter published online July 10 in JAMA Dermatology.Chris

Use of benzodiazepines is not associated with increased dementia risk in older adults, according to a study published online July 2 in&nbsp;BMC Medicine.Ilse vom Hofe, from Erasmus University Medical Center in the Netherlands, and colleagues examined long-term effects of benzodiazepines (anxiolytics or sedative-hypnotics) on neurodegen

Self-imposed use cessation dates (SUCD) for multiuse eye drop bottles leads to significant drug waste and associated costs, according to a report published online July 1 in&nbsp;Ophthalmology.John M. Tan, from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues quantified the volume of drugs discarded in ambula

For older adults with type 2 diabetes (T2D), use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is not associated with a significantly increased risk for suicidal ideation and behaviors, according to a study published online July 16 in the Annals of Internal Medicine.Huilin Tang, from the University of Florida College of Phar

Compared with other antidiabetic classes, metformin and sodium glucose co-transporter-2 inhibitors (SGLT2is) exhibit significantly lower dementia risk, according to a review published online May 3 in the American Journal of Preventive Medicine.Yongjun Sunwoo, from the College of Pharmacy at Kyung Hee University in Seoul, South Korea, an

For patients presenting with acute pain, the quantity of opioids consumed during two weeks after emergency department discharge is low and varies across pain conditions, according to a study published online July 15 in CMAJ, the journal of the Canadian Medical Association.Raoul Daoust, M.D., from Sacré-Coeur Hospital in Montreal, and co

More than four years after the pandemic began, childhood vaccination rates worldwide have yet to recover, a new report shows.The latest data, issued Monday by the World Health Organization and the United Nations International Children’s Emergency Fund (UNICEF), underscore the need for continuing to try to catch-up to pre-pandemic levels.“

Seven patients with illness identified after presumed cosmetic botulinum neurotoxin (BoNT) product injection are described in a case report published in the July 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Christine M. Thomas, D.O., from the CDC in Atlanta, and colleagues charact

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

Three of four patients stop taking semaglutide (Ozempic or Wegovy) two years after being prescribed the glucagon-like peptide-1 receptor agonist (GLP-1 RA) for weight loss, according to new analysis conducted by Prime Therapeutics and Magellan Rx Management (MRx).For the review, pharmacy and medical claims data for 3,364 people with insurance pl

Many people do not know that a primary care provider (PCP) can provide medication for opioid use disorder (MOUD), according to a research letter published online June 28 in&nbsp;JAMA Network Open.Brandon del Pozo, Ph.D., from the Brown University School of Public Health in Providence, Rhode Island, and colleagues surveyed 1,234 individu

Prenatal vaccination with a nonadjuvanted bivalent respiratory syncytial virus (RSV) prefusion F (RSVpreF) protein subunit vaccine is not associated with an increased risk for preterm birth (PTB), according to a study published online July 8 in JAMA Network Open.In a retrospective observational cohort study, Moeun Son, M.D., from the We

The U.S. Food and Drug Administration has approved Zoryve (roflumilast) cream, 0.15 percent, for the treatment of mild-to-moderate atopic dermatitis in adult and pediatric patients (ages 6 years and older).Zoryve is a once-daily, steroid-free cream that the company says will be available at the end of July.The approval was based on resu

For patients with type 2 diabetes (T2D), glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are associated with a reduced risk for 10 of 13 obesity-associated cancers (OACs) compared with insulin, according to a study published online July 5 in JAMA Network Open.Lindsey Wang, from Case Western Reserve University School of Medicine

First-trimester mRNA COVID-19 vaccine exposure is not associated with an increased risk for selected major structural birth defects, according to a study published online July 1 in&nbsp;JAMA Pediatrics.Elyse O. Kharbanda, M.D., M.P.H., from HealthPartners Institute in Minneapolis, and colleagues assessed whether receipt of an mRNA COV

Nirsevimab therapy is effective for reducing the risk for hospitalization for respiratory syncytial virus (RSV)-associated bronchiolitis among infants, according to a study published in the July 11 issue of the New England Journal of Medicine.Zein Assad, M.D., from the Robert Debré University Hospital in Paris, and colleagues conduct

Incentivizing smoking cessation increases smoking cessation through 12 weeks, but not at 26 weeks, when missing data are treated as smoking, according to a study published online July 2 in JAMA Network Open.Darla E. Kendzor, Ph.D., from the University of Oklahoma Health Sciences Center in Oklahoma City, and colleagues randomly assign

More than two-thirds of children with conjunctivitis have a prescription filled for topical antibiotics within one day of an ambulatory care visit, according to a research letter published online June 27 in JAMA Ophthalmology.Daniel J. Shapiro, M.D., M.P.H., from the University of California, San Francisco, and colleagues examined pr

From 1999 to the mid-2000s, the proportion of U.S. adults aged 65 years or older who used prescription medications increased, according to a research letter published online July 1 in JAMA Internal Medicine.Gabriel K. Innes, V.M.D., Ph.D., from the U.S. Food and Drug Administration in Silver Spring, Maryland, and colleagues analyzed dat

Two years after the U.S. Supreme Court overturned Roe v. Wade, more Americans think their state should allow a woman to get a legal abortion for any reason, a new poll finds.Just over 6 in 10 of those questioned say women should have that right, compared to just under 50% of Americans who held the same belief in 2021, the new <a href="https://ap

Tirzepatide is associated with significantly greater weight loss than semaglutide for adults with overweight or obesity, according to a study published online July 8 in JAMA Internal Medicine.Patricia J. Rodriguez, Ph.D., from Truveta Inc. in Bellevue, Washington, and colleagues compared on-treatment weight loss and rates of gastrointest

For individuals with opioid use disorder receiving methadone maintenance treatment (MMT), eight weeks of acupuncture is superior to sham acupuncture for reducing methadone dose and opioid craving, according to a study published online July 9 in the Annals of Internal Medicine.Liming Lu, M.D., from the Guangzhou University of Chinese Medi

For patients with cirrhosis and nonvalvular atrial fibrillation (AF), initiators of rivaroxaban or warfarin versus apixaban have significantly higher rates of major hemorrhage, according to a study published online July 9 in the Annals of Internal Medicine.Tracey G. Simon, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and co

Second- or third-line treatment with tisotumab vedotin is efficacious for patients with recurrent cervical cancer, according to a study published in the July 4 issue of the New England Journal of Medicine.Ignace Vergote, M.D., Ph.D., from Universitaire Ziekenhuizen Leuven in Belgium, and colleagues conducted a phase 3, multinational, ope

For individuals with advanced chronic kidney disease (CKD), angiotensin-converting enzyme inhibitor (ACEi) or angiotensin-receptor blocker (ARB) treatment is associated with a reduced risk for kidney failure with replacement therapy (KFRT) but not death, according to a study published online July 2 in the Annals of Internal Medicine.Elai

Access to medication abortion using history-based (no-test) eligibility assessment, including through telehealth, and mailing of mifepristone lead to similar rates of complete abortion as in-person care with ultrasonography, according to a study published online June 24 in the Journal of the American Medical Association.Lauren J. Ralph,

In a trial involving patients with therapy-refractory cancer treated with approved targeted or immunotherapies, matched to their tumor molecular profile but outside their registered indications, those for whom a waiver was granted had similar serious adverse event rates and clinical benefit rates as those who did not receive a waiver, according to a stu

Semaglutide is associated with nonarteritic anterior ischemic optic neuropathy (NAION) among patients with type 2 diabetes (T2D) and those with overweight/obesity, according to a study published online July 3 in JAMA Ophthalmology.Jimena Tatiana Hathaway, M.D., M.P.H., from the Harvard T.H. Chan School of Public Health in Boston, and

Higher COVID-19 vaccination rates are associated with a lower prevalence of parent-reported childhood asthma symptoms, according to a research letter published online July 3 in JAMA Network Open.Matthew M. Davis, M.D., from Nemours Children's Health in Wilmington, Delaware, and Lakshmi K. Halasyamani, M.D., from Endeavor Health in Eva

Sexually active adolescents seeking care in the emergency department have a high risk for pregnancy, and the emergency department may provide a feasible environment to offer contraception counseling, according to a study published online June 28 in&nbsp;JAMA Network Open.Hannah Canter, M.D., from Oregon Health and Science University i

A new drug to treat Alzheimer's disease was approved by the U.S. Food and Drug Administration on Tuesday.In clinical trials, donanemab (Kisunla) modestly slowed the pace of thinking declines among patients in the early stages of the m

U.S. health officials announced Tuesday that the federal government will pay Moderna $176 million to speed development of a pandemic flu vaccine based on mRNA technology.Such a vaccine could be used to treat bird flu in people, as concern grows about&nbsp;H5N1 cases spreading in dairy cows&nbsp;across the country, the U.S. Department of Health a

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

For eight first-line antidepressants, small differences are seen in mean weight change, with the least weight gain with bupropion, according to a study published online July 2 in the Annals of Internal Medicine.Joshua Petimar, Sc.D., from Harvard Medical School and Harvard Pilgrim Health Care Institute in Boston, and colleagues conducted

For patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line treatment, according to a study published online June 26 in the New England Journal of Medicine.Byoung C. Cho, M.D., Ph.D., from the Yonsei Cancer Ce

Almost 90 percent of medical centers report cancer drug shortages, which often impact clinical trials, according to the results of a National Comprehensive Cancer Network survey.Following data published one year ago and six months ago illustrating shortages of crucial cancer drugs, the National Comprehensive Cancer Network published new results

A small number of surgical procedures, including orthopedic procedures and cesarean delivery, account for a large proportion of opioid prescriptions dispensed after surgery, according to a study published online June 26 in JAMA Network Open.Dominic Alessio-Bilowus, from Michigan Medicine in Ann Arbor, and colleagues examined the surgica

Patients with severe asthma initiating biologics exhibit clinical responses and super-responses, but 40 to 50 percent do not meet response criteria, according to a study published online June 22 in Allergy.Eve Denton, M.B.B.S., from Alfred Health in Melbourne, Australia, and colleagues examined responsiveness to biologics in a real-worl

In a clinical practice guideline issued by the American Society for Radiation Oncology and published online June 18 in Practical Radiation Oncology, recommendations are presented for the use of radiation therapy (RT) for management of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC).Danielle N. Margali

The U.S. Supreme Court on Thursday struck down a controversial settlement that drug maker Purdue Pharma had reached with victims of the opioid epidemic.The ruling threatens a massive bankruptcy plan that would have protected the Sackler family, which controls the compan

As a summer wave of COVID infections rolls across the country, U.S. health officials have recommended that all Americans over the age of 6 months get one of the updated COVID vaccines when they become available this fall.The recommendation was issued Thurs

Only one-quarter of adults who needed opioid use disorder (OUD) treatment in 2022 received medications for OUD, according to research published in the June 27 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Deborah Dowell, M.D., from the CDC in Atlanta, and colleagues characterized U.

Immunoglobulin replacement therapy (IgRT) is associated with reductions in hypogammaglobulinemia, infections, severe infections, and associated antimicrobial use among real-world patients with chronic lymphocytic leukemia (CLL) or non-Hodgkin lymphoma (NHL), according to a study published online June 21 in Blood Advances.Jacob D. Soum

For adults with obesity, without diabetes, combining exercise with the glucagon-like peptide-1 receptor agonist (GLP-1 RA), liraglutide, is effective for weight loss, while preserving bone health, according to a study published online June 25 in JAMA Network Open.Simon Birk Kjær Jensen, Ph.D., from the University of Copenhagen in Denm

Inhaled insulin is associated with improved hemoglobin A1c (HbA1c) levels over 16 weeks among adults with type 1 diabetes when compared to usual care, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.Irl B. Hirsch, M.D., from the University of Washington in S

For children with eosinophilic esophagitis, dupilumab results in a significantly higher percentage of histologic remission, according to a study published in the June 27 issue of the New England Journal of Medicine.Mirna Chehade, M.D., M.P.H., from Icahn School of Medicine at Mount Sinai in New York City, and colleagues randomly assig

PIK3CA mutational status may be beneficial for predicting response to addition of the cyclooxygenase 2 (COX-2) inhibitor celecoxib to standard adjuvant chemotherapy in stage III resected colon cancer, according to a study published online June 18 in the Journal of Clinical Oncology.Jonathan A. Nowak, M.D., Ph.D., from Brigham

In new vaccination guidance issued Wednesday, U.S. health officials now recommend that all Americans aged 75 and older get an RSV vaccine before fall arrives.However, those a bit younger -- ages 60 to 74 -- should only seek the shot if they are vulnerable to severe RSV because of chronic medical conditions such as lung or heart disease, or if

For patients with chronic migraine (CM), with and without medication overuse, atogepant is efficacious, according to a study published online June 27 in Neurology.Peter J. Goadsby, M.D., Ph.D., from King's College London, and colleagues examined the efficacy of atogepant for the preventive treatment of CM in participants with and wit

Benralizumab yields a greater histologic response than placebo for patients with eosinophilic esophagitis, but does not affect dysphagia symptoms, according to a study published in the June 27 issue of the New England Journal of Medicine.Marc E. Rothenberg, M.D., Ph.D., from the Leiden University Medical Center in the Netherlands, an

Multivitamin (MV) use is not associated with mortality benefit among U.S. adults, according to a study published online June 26 in JAMA Network Open.Erikka Loftfield, Ph.D., M.P.H., from the National Institutes of Health in Rockville, Maryland, and colleagues estimated the association of MV use with mortality risk, accounting for con

Glofitamab (Glofit) plus gemcitabine and oxaliplatin (GemOx) is superior to rituximab (R)-GemOx for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL), according to a study presented at the annual hybrid congress of the European Hematology Association, held from June 13 to 16 in Madrid.Jeremy Abramson, M.D., from the Massachusett

The Dobbs v Jackson Women's Health Organization decision, allowing states to strengthen restrictions on abortion access, was associated with declines in prescription fills for oral contraceptives, according to a study published online June 26 in JAMA Network Open.Dima M. Qato, Pharm.D., M.P.H., Ph.D., from the University of

Pediatric surgical opioid prescribing is concentrated among a small number of procedures, especially tonsillectomy and/or adenectomy, according to a study published online June 26 in Pediatrics.Kao-Ping Chua, M.D., Ph.D., from the Institute for Healthcare Policy and Innovation in Ann Arbor, Michigan, and colleagues conducted a cross-

For patients with obesity-related heart failure with preserved ejection fraction (HFpEF), semaglutide reduces body weight to a greater extent in women but yields similar improvements in heart failure-related symptoms in men and women, according to a study published online June 23 in the Journal of the American College of Cardiology to coinc

Tirzepatide reduces the apnea-hypopnea index (AHI) among individuals with moderate-to-severe obstructive sleep apnea and obesity, according to a study published online June 21 in the New England Journal of Medicine to coincide with the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.At

For patients with prurigo nodularis (PN) and chronic pruritus of unknown origin (CPUO), abrocitinib, a Janus kinase 1 inhibitor, is effective and well tolerated, according to a study published online June 5 in JAMA Dermatology.Shawn G. Kwatra, M.D., from the University of Maryland School of Medicine in Baltimore, and colleagues examine

mRNA COVID-19 vaccination during pregnancy is not associated with an increased risk of adverse pregnancy outcomes, according to a study published in the June issue of&nbsp;Obstetrics &amp; Gynecology.Kimberly K. Vesco, M.D., M.P.H., from Kaiser Permanente Center for Health Research in Portland, Oregon, and colleagues evaluated the asso

Psychostimulants may help opioid use disorder (OUD) outcomes in pregnant women, according to a study published online June 11 in&nbsp;Nature Mental Health.Kevin Y. Xu, M.D.,&nbsp;M.P.H., from the Washington University School of Medicine in St. Louis, and colleagues used U.S. multistate administrative data to examine the risks and benef

Semaglutide may cut incidence and recurrence of alcohol use disorder (AUD) in patients with obesity, according to a study published online May 28 in&nbsp;Nature Communications.William Wang, from Case Western Reserve University in Cleveland, and colleagues used electronic health records of 83,825 patients with obesity to examine associa