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All articles tagged: Rheumatology

HealthDay 06 September at 03.41 PM

Lung Complications + Rheumatoid Arthritis Increase Risk for Lung Cancer

The risk for lung cancer is high in patients with rheumatoid arthritis (RA) and pulmonary complications, according to a study published online Sept. 3 in Modern Rheumatology.Shunsuke Mori, M.D., Ph.D., from the Kumamoto Saishun Medical Center in Koshi, Japan, and colleagues assessed the incidence and predictive factors of lung canc

HealthDay 06 September at 03.36 PM

CT-Based Radiomics Nomogram Can ID RA-Linked Interstitial Lung Disease

A computed tomography (CT)-based radiomics nomogram model can achieve favorable efficacy for predicting low-risk patients with rheumatoid arthritis (RA)-associated interstitial lung disease (ILD), according to a study published online July 31 in Frontiers in Immunology.Nie Han, from Guanghua Hospital Affiliated to the Shanghai Universit

MedScape 06 September at 11.00 AM

Colchicine Drug Interactions May Not Affect Safety, Efficacy

Changes in colchicine pharmacokinetics due to drug-drug interactions did not result in meaningful changes in its safety and effectiveness, according to a secondary analysis of a clinical trial.

MedScape 06 September at 10.00 AM

Rheumatoid Arthritis: Whole-Food Diet May Be Protective

The more ultra-processed foods a person consumed, the higher their risk for the inflammatory autoimmune disease.

MedScape 06 September at 06.10 AM

High Temperatures Also Exacerbate Raynaud, Study Suggests

Both extreme heat and cold were tied to more severe episodes of Raynaud phenomenon in a study of participants with systemic sclerosis.

MedScape 05 September at 10.17 AM

New Insights into Management of Sjögren-Related Lymphoma

Two European studies reported on a potentially strong predictive biomarker for marginal lymphoma in Sjögren disease and the effectiveness of systemic therapy vs localized treatment or watch and wait.

HealthDay 04 September at 10.59 PM

Causal Link Seen for High Ferritin, Serum Iron With Lower Risk for RA

Genetic predisposition to high ferritin and serum iron status is associated with a lower risk for developing rheumatoid arthritis (RA), according to a study published online Aug. 29 in Global Medical Genetics.Boyuan Wu, from the School of Global Public Health at New York University in New York City, used genetic data from a large gen

MedScape 04 September at 05.01 PM

Teclistamab Shows Promise in Refractory Autoimmune Diseases

In small studies, teclistamab significantly improved autoimmune disease activity and demonstrated a good safety profile.

MedScape 04 September at 07.26 AM

RA Increases Stroke Risk in Atrial Fibrillation

The presence of rheumatoid arthritis increased the risk for stroke in patients with atrial fibrillation, a retrospective study showed.

MedScape 04 September at 04.17 AM

Higher RA Disease Activity May Accelerate Renal Impairment

The risk of developing stage 3b chronic kidney disease was nearly doubled in patients with rheumatoid arthritis who had high disease activity.

HealthDay 03 September at 04.04 PM

High-Intensity Interval Training, Strength Exercise Beneficial in RA

For patients with rheumatoid arthritis, high-intensity interval training (HIIT) and strength exercise are beneficial for cardiovascular health, physical fitness, and overall health, according to a study published online Aug. 23 in the British Journal of Sports Medicine.Annelie Bilberg, Ph.D., from the University of Gothenburg Sahlgrens

MedScape 02 September at 05.00 AM

The Hidden Impact of Systemic Sclerosis Without Scleroderma

Systemic sclerosis sine scleroderma may account for almost 10% of cases and shares clinical features with limited cutaneous systemic sclerosis.

MedScape 30 August at 10.44 AM

'Egregious' Ustekinumab Price Jump Shows Need for IRA

OIG reports showed a spike in ustekinumab costs for patients in Medicare Part D. Experts said Inflation Reduction Act changes in Medicare drug coverage will soften the blow.

MedScape 30 August at 07.39 AM

A Tale of Rheumatologist Volunteers Overseas and in the US

Two rheumatologists give insights about the great rewards of rheumatology volunteer work while also providing insights on its challenges across different settings.

HealthDay 29 August at 04.08 PM

Greater Alcohol Intake Tied to Higher Gout Risk

Higher consumption of alcoholic beverages is associated with a higher risk for gout among both sexes, according to a study published online Aug. 28 in JAMA Network Open.Jie-Qiong Lyu, from Suzhou Medical College of Soochow University in China, and colleagues evaluated the consumption of total and specific alcoholic beverages in a

MedScape 29 August at 02.48 AM

Air Pollution: A Hidden Trigger for Giant Cell Arteritis?

Exposure to high levels of particulate matter with diameter ≤ 10 μm was associated with an increased risk for giant cell arteritis but not ischemic complications, an observational study showed.

MedScape 28 August at 02.57 AM

Support Program Boosts Health in Juvenile Arthritis Patients

A support program for children recently diagnosed with juvenile idiopathic arthritis improved their physical, emotional, and psychosocial well-being, a recent study showed.

HealthDay 27 August at 09.50 PM

Team-Based Documentation Can Increase Visit Volume, Cut Documentation Time

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

MedScape 27 August at 02.30 AM

Bimekizumab Lowers Uveitis Rates in Axial Spondyloarthritis

In patients with axial spondyloarthritis, bimekizumab — a dual interleukin-17A/F inhibitor — showed a lower incidence rate of uveitis, suggesting protective effects against acute anterior uveitis.

MedScape 26 August at 12.36 PM

Cigna to Remove AbbVie's Humira From Some Drug Reimbursement Lists Next Year

Cigna said on Monday it will remove AbbVie’s blockbuster rheumatoid arthritis drug Humira from some of its lists of preferred drugs for reimbursement in 2025, and recommend...

MedScape 23 August at 12.16 AM

Failed Remission in Early RA No Better With Added Etanercept

Adding etanercept in patients with early RA who responded insufficiently to initial methotrexate and bridging glucocorticoids did not result in better disease control than leflunomide at 104 weeks.

HealthDay 22 August at 09.33 AM

Americans Have Mixed Feelings About AI in Health Care, Poll Finds

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

MedScape 22 August at 04.11 AM

What to Know About JAKne — JAK Inhibitor-Associated Acne

Janus kinase (JAK) inhibitor-associated acne may be overlooked outside of dermatology, experts said.

MedScape 22 August at 03.22 AM

GLP-1 Receptor Agonists May Lower Mortality in IMIDs and T2D

GLP-1 RAs were associated with a decreased risk for all-cause mortality and MACE in patients with immune-mediated inflammatory diseases and type 2 diabetes.

MedScape 21 August at 05.03 AM

Mobile App Shows Promise in Managing Fibromyalgia Symptoms

A self-guided smartphone-based behavioral therapy could be a viable treatment for fibromyalgia, a recent study showed.

HealthDay 20 August at 03.50 PM

More Than Half of Older Adults Very Concerned About Medical Costs

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

MedScape 19 August at 09.05 AM

High Prevalence of Tendon Issues in Hand Osteoarthritis

Patients with hand osteoarthritis showed a high prevalence of tendon damage and inflammation of the synovial membrane surrounding the tendons.

HealthDay 14 August at 03.56 PM

Gastroesophageal Reflux Disease Tied to Increased Risk for Rheumatoid Arthritis

Gastroesophageal reflux disease (GERD) increases the risk for rheumatoid arthritis (RA), according to a study published online Aug. 1 in&nbsp;Scientific Reports.Quan Yuan, from the First Hospital of Jilin University in Changchun, China, and colleagues used Mendelian randomization (MR) to assess the causal relationship between GERD an

HealthDay 14 August at 03.45 PM

Clinicians Are Interested in Climate Change Education

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

MedScape 14 August at 06.40 AM

Diagnosing Chronic Back Pain in Psoriasis, Uveitis, Colitis

A substantial proportion of patients with psoriasis, uveitis, or colitis and undiagnosed chronic back pain had axial spondyloarthritis, a study involving two multicenter cohorts showed.

HealthDay 12 August at 04.03 PM

Causal Relationship Seen for RA and Adverse Pregnancy Outcomes

There is a positive causal association for rheumatoid arthritis and adverse pregnancy outcomes (APOs), according to a study published online July 31 in&nbsp;BMC Pregnancy &amp; Childbirth.Tongmin Chang, from the Cheeloo College of Medicine at Shandong University in Jinan, China, and colleagues explored the potential causal relationships

HealthDay 09 August at 08.08 PM

Rheumatoid Arthritis Tied to Higher Risk for Lung Cancer

Rheumatoid arthritis (RA) is associated with a significantly increased risk for lung cancer, according to a study published online July 28 in&nbsp;Arthritis &amp; Rheumatology.Rebecca T. Brooks, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues evaluated lung cancer risk in people with RA and RA-interstitial lung disease

HealthDay 08 August at 03.42 PM

ChatGPT Only Gets Diagnoses Correct Half of the Time

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

HealthDay 02 August at 03.39 PM

Smartphone-Based Acceptance and Commitment Therapy Aids Fibromyalgia

Digital acceptance and commitment therapy (ACT) is safe and efficacious compared with daily digital symptom tracking for managing fibromyalgia, according to a study published online July 8 in&nbsp;The Lancet.R. Michael Gendreau, M.D., Ph.D., from Gendreau Consulting in Poway, California, and colleagues randomly assigned 275 adult partici

HealthDay 31 July at 03.38 PM

Cognitive Impairment More Often Experienced by Patients With RA

Patients with rheumatoid arthritis (RA) with moderate-to-high inflammation are more likely to experience cognitive impairment, according to a study published online July 29 in RMD Open.Natalia Mena-Vázquez, Ph.D., from the Biomedical Research Institute of Malaga and Platform in Nanomedicine in Spain, and colleagues performed a cross-

HealthDay 24 July at 06.03 PM

Positive Causal Association Between Rheumatoid Arthritis, Bronchiectasis

There is a causal association between genetically predicted rheumatoid arthritis (RA) and increased risk of bronchiectasis, according to a study published online June 19 in Frontiers in Medicine.Yuanyuan Li, from the Wuhan Fourth Hospital in China, and colleagues obtained RA genome-wide association study (GWAS) data and bronchiectasi

HealthDay 24 July at 03.19 PM

Depression, Anxiety, Fibromyalgia Common With Rheumatoid Arthritis, Osteoarthritis

Approximately four in 10 patients with osteoarthritis (OA) or rheumatoid arthritis (RA) have anxiety, depression, or fibromyalgia, according to a study published online July 16 in&nbsp;ACR Open Rheumatology.Juan Schmukler, M.D., from the Rush University Medical Center in Chicago, and colleagues analyzed the prevalence of anxiety, dep

HealthDay 23 July at 10.41 PM

Mediterranean Diet May Aid Mental Health in Rheumatoid Arthritis Patients

Greater adherence to a Mediterranean diet is associated with lower odds of depression in individuals with rheumatoid arthritis, according to a study published online July 5 in the&nbsp;Journal of Health, Population and Nutrition.Liya Ma, from Honghui Hospital at Xi’an Jiaotong University in China, and colleagues explored the associatio

HealthDay 22 July at 03.35 PM

Socioeconomic Factors Linked to Persistently Active Rheumatoid Arthritis

Socioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 in RMD Open.Maryam Adas, from the King's College London Faculty of Life Sciences &amp; Medicine, and colleagues examined which biological and nonbiological factors are associated w

HealthDay 12 July at 10.21 PM

More Women Than Men Experience Nonphysical Violence in Health Care Workforce

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

HealthDay 11 July at 12.45 PM

Scientists Spot Cause of Lupus, Way to Reverse It

Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.The disease appears to be caused by malfunctions in an immune system pathway that regulates cells’ response to environmental pollutants, bacteria and toxins.Insufficient activation of this pathwa

HealthDay 10 July at 04.02 PM

Air Pollutant Exposure Linked to Increased Risk for Incident Lupus

Air pollutant exposure is associated with an increased likelihood of developing incident systemic lupus erythematosus (SLE), according to a study published online July 10 in Arthritis &amp; Rheumatology.Meiqi Xing, from the Huazhong University of Science and Technology in Wuhan, China, and colleagues examined the associations between

HealthDay 05 July at 02.26 PM

Postpandemic Physician Revenue Recovery Varies by Specialty, Practice Type

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

HealthDay 02 July at 04.01 PM

Mean Cost of Bringing New Drug to U.S. Market Is $879.3 Million

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

HealthDay 01 July at 03.16 PM

Psoriasis, With or Without Psoriatic Arthritis, Associated With Fatigue

Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the Journal of the American Academy of Dermatology.Lea Nymand, from Bispebjerg Hospital and the University of Copenhagen in Denmark, and colleagues explored the characteristics of fatigue and it

HealthDay 28 June at 03.00 PM

RA Patients With Mono-, Oligo-Arthritis, High PGA Remain Most Fatigued

Rheumatoid arthritis (RA) patients with mono- or oligo-arthritis and high Patient Global Assessment (PGA) at diagnosis remain the most fatigued, according to a study published in the June issue of Rheumatology.Anna M.P. Boeren, from the Leiden University Medical Center in the Netherlands, and colleagues studied Disease Activity&nbsp;Sco

HealthDay 27 June at 03.03 PM

hs-cTnT Linked to MACE, Mortality in Rheumatoid Arthritis

For patients with rheumatoid arthritis (RA), a detectable level of high-sensitivity cardiac troponin T (hs-cTnT) is associated with increased risk of major adverse cardiovascular events (MACE) and all-cause mortality, according to a research letter published online June 15 in the Journal of Rheumatology.Brittany N. Weber, M.D., Ph.D.,

HealthDay 26 June at 07.46 PM

Fatigue With Rheumatoid Arthritis Tied to Disease Activity, Education Level

The Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional Questionnaire (BRAF-MDQ) and Brief Fatigue Inventory (BFI-C) scores show consistency in assessing fatigue with rheumatoid arthritis (RA), according to a study published online June 14 in&nbsp;Immunity, Inflammation and Disease.Jun Zhou, from the Affiliated Suqian First People

HealthDay 25 June at 03.05 PM

Smoking + RA With Obstructive Pattern Shows Less Spirometry Decline

Patients who have smoked with rheumatoid arthritis (RA) and an obstructive pattern may be a unique phenotype, according to a study published online June 17 in&nbsp;RMD Open.Keigo Hayashi, M.P.H., from Brigham and Women's Hospital in Boston, and colleagues compared longitudinal changes in spirometric measures over five to seven years be

HealthDay 21 June at 11.00 PM

FDA Expands Pediatric Indication for Rinvoq

The U.S. Food and Drug Administration has expanded indications for Rinvoq (upadacitinib) to now include pediatric patients (ages 2 years and older) with polyarticular juvenile idiopathic arthritis (pJIA) and psoriatic arthritis (PsA).Rinvoq is indicated for pediatric patients with an inadequate response or intolerance to one or more tumor necros

HealthDay 20 June at 08.56 PM

2021 to 2022 Saw Decrease in Telemedicine Use in Past 12 Months

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

HealthDay 18 June at 09.11 PM

Approximately 7 Percent of U.S. Population Uninsured in 2023

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

HealthDay 18 June at 09.50 AM

Pandemic-Era Tax Credits Made Healthcare More Affordable, But They're Set to Expire

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

HealthDay 13 June at 10.58 PM

Health Care Spending Growth Projected to Outpace GDP to 2032

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

HealthDay 12 June at 03.05 PM

Adverse Effects of Medical Treatment Increasing Worldwide

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

MedScape 30 May at 03.21 AM

Metformin Initiation Cuts Gout Risk in Prediabetes

Metformin use not only prevented the progression to diabetes but also lowered the risk for gout in individuals with prediabetes.

MedScape 30 May at 03.05 AM

SpA Screening IDs 'High Burden of Need' in Patients With IBD

More than 40% of patients with IBD screened positive for joint pain in a multicenter study, yet few patients had seen a rheumatologist in the past year.

HealthDay 29 May at 09.17 PM

2007 to 2019 Saw Increase in Inflation-Adjusted Health Care Spending

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

MedScape 27 May at 05.51 AM

Neuropsych Symptoms an Important, Overlooked Feature of SLE

Findings from a qualitative study suggested a greater need for rheumatology clinicians to initiate discussions with patients about neuropsychiatric symptoms.

MedScape 27 May at 02.25 AM

High NSAID Use for axSpA May Not Raise Risk for Hypertension

There was no difference in the risk for hypertension between patients with axial spondylarthritis who were high and low NSAID users, according to new data.

HealthDay 23 May at 03.44 PM

Rates of Severe Multiple Drug Intolerance Syndrome Up in Fibromyalgia, IBS

Patients with fibromyalgia and irritable bowel syndrome (IBS) have increased rates of severe multiple drug intolerance syndrome (MDIS), according to a study published in the May issue of the Journal of Allergy and Clinical Immunology: In Practice.Alicia A. Alvarez, M.D., from Sarasota Memorial Hospital in Florida, and colleagues conduc

HealthDay 22 May at 09.01 PM

FDA Approves Belimumab Autoinjector for Pediatric Systemic Lupus Erythematosus

The U.S. Food and Drug Administration has approved a 200-mg subcutaneous route of administration of Benlysta (belimumab) for patients 5 years of age and older with active systemic lupus erythematosus (SLE) who are receiving standard therapy.The B-lymphocyte stimulator-specific inhibiting monoclonal antibody was previously approved for children

MedScape 22 May at 03.24 AM

Risks for Hydroxychloroquine Retinopathy Described in Detail

Including over 4670 patients, this is "the largest cohort study to date looking specifically at the association of [HCQ] retinopathy with risk factors," one expert said.

MedScape 21 May at 04.16 PM

FDA Approves Belimumab Autoinjector for Pediatric Lupus

This enables at-home administration of the medication, which was previously available only via intravenous infusion.

HealthDay 21 May at 02.49 PM

Neuropsychiatric Symptoms Can Present at Any Stage of Lupus

For patients with systemic lupus erythematosus (SLE), neuropsychiatric (NP) symptoms can first present at any stage in the disease course, according to a study published online May 20 in eClinicalMedicine.Melanie Sloan, Dr.P.H., from the University of Cambridge in the United Kingdom, and colleagues obtained patient reports of the timing

MedScape 16 May at 03.19 AM

In RA Treatment, Don't Overlook Underlying CV Risks

Disease-modifying antirheumatic drugs can reduce some cardiovascular risk in patients with rheumatoid arthritis, but questions remain if that's enough when statin use lags.

MedScape 16 May at 03.14 AM

Another Benefit of Gout Treatment: CV Risk Reduction

Growing evidence suggests that a guideline-directed, treat-to-target strategy in patients with gout not only controls the disease but also reduces cardiovascular risks.

MedScape 14 May at 09.04 AM

Are Diabetes Drugs Set to Move OA Management Forward?

Researchers are looking to see if GLP-1 receptor agonists, DPP4 inhibitors, and SGLT2 inhibitors have beneficial effects in osteoarthritis.

HealthDay 13 May at 10.34 PM

Physicians With Disabilities May Experience Depersonalization

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

HealthDay 13 May at 03.50 PM

Study Identifies Factors Associated With Hydroxychloroquine Retinopathy

Factors associated with an increased risk for hydroxychloroquine retinopathy have been identified and include female sex, older age, and chronic kidney disease stage 3 or greater, according to a study published online May 9 in JAMA Network Open.April M. Jorge, M.D., from Massachusetts General Hospital in Boston, and colleagues identified

HealthDay 13 May at 03.46 PM

Coexistence of Psoriatic Arthritis, Atopic Dermatitis May Offer Treatment Insights

Psoriatic arthritis (PsA) and atopic dermatitis (AD) can coexist, and the presence of both conditions may mean special attention should be given to selecting optimal treatment, according to a study published online April 17 in the Journal of Personalized Medicine.Georgiana Strugariu, from "Grigore T. Popa" University of Medicine and Phar

MedScape 13 May at 05.27 AM

Ultrasound-Aided Diagnosis of GCA Is Accurate, Avoids Biopsy

In a prospective study, all patients diagnosed with giant cell arteritis using ultrasound maintained their diagnosis for up to 2 years of follow-up.

MedScape 13 May at 05.24 AM

Nipocalimab's Unique Mechanism Gets Second Chance in RA

The trial proved that nipocalimab reduced IgG antibodies, including anti-citrullinated protein autoantibodies, but the primary endpoint was missed.

HealthDay 10 May at 12.42 PM

Cyberattack Cripples Major U.S. Health Care Network

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

MedScape 10 May at 08.42 AM

Serum Metabolome Identifies Cancer in Rheumatic Disease

A recent study revealed that alterations in the serum metabolome indicated the presence of concurrent cancer in patients with rheumatic diseases or paraneoplastic syndromes mimicking rheumatic symptoms.

MedScape 10 May at 04.24 AM

Higher NSAID Dose Raises CVD Risk in Ankylosing Spondylitis

NSAIDs, the primary pain management therapy for AS, increased the risk for vascular events and congestive heart failure when administered in high doses to patients with AS.

MedScape 10 May at 03.06 AM

bDMARDs Prevent ESRD in Most Patients With AA Amyloidosis

bDMARD therapy preserved renal function in 75% of patients with AA amyloidosis, but the remaining 25% progressed to ESRD despite receiving bDMARD therapy.

MedScape 09 May at 05.52 AM

Why Obstetric, Autoimmune History Matter for Women's CV Risk

A history of pregnancy complications can put women with autoimmune disease at a higher risk for CVD. Prophylaxis during pregnancy may avoid those complications in the first place.

MedScape 08 May at 04.10 AM

Diacerein, Resveratrol, Botulinum Toxin Disappoint in Knee OA

Data do not back the use of diacerin, resveratrol, or botulinum toxin for knee OA, according to the results of well-performed, multicenter, randomized controlled clinical trials.

MedScape 08 May at 02.04 AM

Thigh Muscle Modifies OA Risk From Weight-Bearing Exercise

People with low lower-limb muscle mass should consider non–weight-bearing physical activities, along with strengthening exercises, to potentially reduce their risk of developing knee OA.

MedScape 07 May at 05.36 AM

Several Novel Injectables Show Early Promise in Knee OA

Data on several novel injectable drugs were presented at the World Congress on Osteoarthritis, as well as updated data on the gene therapy XT-150.

HealthDay 06 May at 09.00 PM

Doppler Ultrasound Feasible for First-Line Diagnosis of Giant Cell Arteritis

For patients with high clinical suspicion of giant cell arteritis (GCA), color Doppler ultrasound of the temporal artery as a first-line diagnostic tool can avoid the need for other diagnostic tests, according to a study published online May 7 in the Annals of Internal Medicine.Guillaume Denis, M.D., from the Centre Hospitalier Rochefort

MedScape 03 May at 04.51 AM

Most RA Patients Meet EMA's JAK Inhibitor Warning Criteria

Recent regulatory warnings could mean that four in five patients with RA may not be prescribed JAK inhibitors unless there is no other alternative.

HealthDay 02 May at 03.37 PM

Algorithm From EHR Can ID Common Variable Immunodeficiency Disease

A machine learning algorithm can identify patients with common variable immunodeficiency disease (CVID) from their electronic health records, according to a study published in the May 1 issue of Science Translational Medicine.Due to the low prevalence and extensive heterogeneity in CVID phenotypes, resulting in delayed diagnoses and tre

MedScape 02 May at 12.34 PM

FDA OKs High-Concentration of Adalimumab Biosimilar Cyltezo

Unlike the low-concentration formulation of adalimumab-adbm, launched July 1, 2023, this high-concentration version has not yet been granted an interchangeability designation.

MedScape 02 May at 12.13 AM

Lower CVD Risk With Stable DMARD Therapy in Seropositive RA

Patients with seropositive RA on stable DMARD therapy showed a CVD risk comparable with that of the general population, unlike those whose treatment regimen was not stable.

MedScape 01 May at 04.44 PM

Updated Sjögren Disease Guideline Takes New Approach, Format

An updated guideline on the management of Sjögren disease has been produced by the British Society for Rheumatology, providing practical advice for healthcare professionals and the people they treat.

MedScape 30 April at 06.53 AM

Reasons for Heightened Thrombotic Risk in RA Remain Unclear

Irrespective of age, duration of disease, and other factors, people with rheumatoid arthritis have a consistently higher risk for venous thromboembolism than the general population.

HealthDay 29 April at 03.52 PM

People With Acute Calcium Pyrophosphate Face Doubled Risk for Fracture

Fracture risk is nearly doubled in individuals with acute calcium pyrophosphate (CPP) crystal arthritis, according to a study recently published in Arthritis &amp; Rheumatology.Sara K. Tedeschi, M.D., M.P.H., from Brigham and Women’s Hospital in Boston, and colleagues compared fracture risks (humerus, wrist, hip, or pelvis) in 1,148 pa

MedScape 29 April at 07.29 AM

Optimized Hospital Care Improves Gout Treatment Uptake

Almost all people who received in-hospital treatment for a gout flare were using urate-lowering therapy within 6 months of discharge after a multifaceted intervention with nurse-led follow-up.

MedScape 26 April at 07.27 AM

Rheumatology Data Reflect Poor Adoption of ICD-10

Inflammatory arthritis codes increased from 14 to 425 from ICD-9 to ICD-10, yet only nine codes were commonly used in practice from 2015 to 2021.

MedScape 26 April at 07.05 AM

British Societies Develop First 'Living' Behçet Guidelines

The British Society for Rheumatology and the British Association of Dermatologists developed guidelines for the management of people living with Behçet's disease.

MedScape 23 April at 05.24 AM

Semaglutide Improves Knee OA Pain, Physical Function

Results of the STEP 9 study in people with knee OA and obesity show that semaglutide not only induced significant weight loss but also improved knee pain and physical function.

MedScape 22 April at 03.15 AM

Sinonasal Symptoms Help Predict GPA Vasculitis Relapse

Patients with GPA were two to three times as likely to experience disease relapse if they scored high on a patient-reported sinonasal symptom test.

MedScape 22 April at 02.19 AM

The Patient Knows Best: PROs in RA Practice and Research

Advanced systems for measuring patient-reported outcomes can help improve care of patients with rheumatoid arthritis and inform clinical research.

MedScape 19 April at 03.55 AM

Investigators Train AI Systems to Predict RA Outcomes

Plugging massive amounts of data from EHRs into AI systems may turn masses of silicon chips into crystal balls for foretelling treatment efficacy.

MedScape 18 April at 03.38 AM

Shared Telehealth Brings Rheumatology Care to Rural Areas

Patients with rheumatic diseases who live in underserved areas may benefit from virtual visits conducted jointly by rheumatologists and PCPs trained in recognizing and managing these conditions.

MedScape 17 April at 05.17 PM

FDA Approves Second Ustekinumab Biosimilar

The biosimilar is expected to be marketed in the United States on or after February 21, 2025.

MedScape 17 April at 06.18 AM

Modifying Gut Microbiota May Enhance DMARD Efficacy in RA

Investigators have found evidence suggesting that bad bugs in the belly may contribute to inflammation in the joints, and that modulating gut microbes could improve rheumatoid arthritis treatment.

MedScape 17 April at 03.02 AM

Guselkumab Provides Long-Term Relief From PsA Symptoms

Guselkumab improved joint swelling, spinal pain, skin symptoms, and overall disease activity in a substantial number of patients with psoriatic arthritis through 2 years.

MedScape 15 April at 02.38 AM

DMARD Taper-to-Discontinuation Approach Increases Flare Risk

In two trials, most patients with RA in remission who tapered csDMARD or TNF inhibitor drugs to withdrawal experienced flares within 3 years.

MedScape 12 April at 06.43 AM

Worldwide Prevalence of PsA: Meta-Analysis Sheds Light

PsA is more prevalent in Europe and North America than in Asia and South America, according to a meta-analysis that assessed the worldwide PsA prevalence.

MedScape 12 April at 04.52 AM

Body Fat Tied to Disease Burden in Biologic-Treated axSpA

Maintaining a healthy body composition is important to improve physical functioning and mobility in patients with axial spondyloarthritis receiving biologics, a new study indicated.

MedScape 12 April at 04.21 AM

High Infection Risk in RA-Associated ILD

A prospective study found that 96% of patients with RA-ILD had at least one serious infection, which proved fatal in 65% of cases.

MedScape 12 April at 03.58 AM

Sub-Q Tocilizumab Gives Durable Long-Term Responses in JIA

Patients with juvenile idiopathic arthritis achieved long-term disease control with subcutaneous tocilizumab treatment, without any new safety concerns, in an LTE study of two trials.

MedScape 11 April at 03.11 AM

Tocilizumab Withdrawal Post Remission in Still's Disease

Longer tocilizumab administration intervals and lower prednisolone doses seemed pivotal for successful tocilizumab withdrawal while maintaining remission in patients with AOSD.

MedScape 11 April at 01.37 AM

Both Parotid and Labial Gland Biopsies Can Diagnose SjS

Although largely similar, some important histopathologic differences were seen in the biopsies of the labial and parotid salivary glands in individuals with suspected SjS.

MedScape 10 April at 03.21 AM

FDA OKs First CAR T-cell Trial for Children With Lupus

The trial is expected to begin this summer and will enroll 12 individuals under age 18 years.

MedScape 08 April at 05.54 PM

PRT and Neuromuscular Exercise Tie at Improving Hip OA

Progressive resistance training or neuromuscular exercise for 12 weeks helped to improve hip function, pain, and quality of life to a similar degree in people with osteoarthritis.

MedScape 08 April at 03.28 AM

Congress Allocates $10 Million for Arthritis Research

This is the first stand-alone arthritis research program under the Department of Defenses' Congressionally Directed Medical Research Programs.

MedScape 05 April at 06.28 AM

Bone Infections Increase After S aureus Bacteremia in RA

The use of orthopedic implants or tumor necrosis factor inhibitors doubled the risk for bone infections in patients with RA who had contracted S aureus bacteremia.

MedScape 04 April at 05.44 AM

How Is Autoimmunity's Sex-Biased E-'Xist'-ence Possible?

Researchers are homing in on a long noncoding RNA fragment called Xist, essential to X chromosome inactivation, as the culprit in sex-biased autoimmune diseases like lupus.

HealthDay 03 April at 03.53 PM

Rheumatic Diseases Have an Impact on Reproductive Health

Rheumatic diseases have a broad impact on reproductive success and pregnancy outcomes, according to a study published online March 20 in&nbsp;Rheumatology.Anne M. Kerola, M.D., Ph.D., from Helsinki University Hospital, and colleagues examined the impact of rheumatic diseases on reproductive health measures, comparing the impacts to t

MedScape 03 April at 05.13 AM

Pediatric CNO Characteristics Can Predict Therapy Needs

Patients with unifocal disease at diagnosis may require shorter nonsteroidal anti-inflammatory drug monotherapy courses than those with multifocal disease.

HealthDay 02 April at 03.44 PM

Biosimilar Biologics Do Not Always Reduce Out-of-Pocket Costs

Biosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 in&nbsp;JAMA Health Forum.Kimberly Feng, M.D., from Brigham and Women’s Hospital in Boston, and colleagues investigated whether biosimilar competition is associa

MedScape 02 April at 08.11 AM

Tuberculosis Screening Gaps Persist in New DMARD Users

Substantial patient safety gaps regarding latent tuberculosis screening persist among new users of biologic or targeted synthetic DMARDs, suggested a nationwide cohort study.

MedScape 01 April at 05.10 PM

First-of-Its-Kind RA Research Summit Offers Diverse Program

The Arthritis Foundation has partnered with the Hospital for Special Surgery to host a 2-day meeting on RA, assembling researchers who pursue a diverse array of strategies to potentially improve care.

MedScape 01 April at 07.34 AM

Early Biologic Initiation Linked to Rapid Improvement of JIA

The findings have implications for insurance rules that require patients to take a DMARD for a minimum period before initiating biologic therapy.

HealthDay 29 March at 03.14 PM

U.S. Doctors Received Industry Payments of $12.13 Billion From 2013 to 2022

U.S. physicians received $12.13 billion from industry from 2013 to 2022, according to a research letter published online March 28 in the Journal of the American Medical Association.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and colleagues examined the distribution of payments within and across specialties and the medica

MedScape 26 March at 02.57 AM

Multiple Social Disadvantages Worsen Kids' Rheumatic Disease

Two recent studies revealed the compounding effects of negative social determinants of health on worse disease presentation and activity over time.

MedScape 25 March at 01.22 PM

Europe's Quest for Earlier Diagnosis of Psoriatic Arthritis

The HIPPOCRATES consortium aims to help predict those who will develop the condition, diagnose it earlier, and one day even prevent it.

HealthDay 22 March at 10.09 PM

Four in 10 Adults Choose Telemedicine Visits

Many patients, including those with the greatest care needs, choose telemedicine even when in-person visits are available, according to a study published online March 22 in&nbsp;JAMA Network Open.Eva Chang, Ph.D., M.P.H., from Advocate Health in Milwaukee, Wisconsin, and colleagues assessed patient characteristics associated with telem

HealthDay 22 March at 03.56 PM

Physicians Concerned About Private Equity's Impact on Health Care

Physicians express largely negative views about the impact of private equity (PE) on the health care system, according to a research letter published online March 11 in&nbsp;JAMA Internal Medicine.Jane M. Zhu, M.D., from Oregon Health and Science University in Portland, and colleagues conducted a survey to assess physicians' views towa

HealthDay 21 March at 10.59 PM

Life Expectancy Increased From 2021 to Reach 77.5 Years in 2022

Life expectancy increased to 77.5 years in 2022, while the age-adjusted rate of drug overdose deaths increased from 2002 to 2022 but did not change from 2021 to 2022, according to two March data briefs published by the National Center for Health Statistics.Kenneth D. Kochanek, from the National Center for Health Statistics in Hyattsville, Mar

MedScape 20 March at 06.23 AM

Telerehab No Worse Than In-Person Care for Chronic Knee Pain

The results are a "game changer" for physical therapy, one expert said, and could help expand access to physiotherapy services to an underserved patient population.

MedScape 20 March at 05.06 AM

Patients With Sjögren Syndrome Fall Into Distinct Subgroups

Those with high systemic disease activity but low symptom burden fared worse over time.

MedScape 18 March at 05.58 AM

Early Diagnosis Improves Clinical Outcomes in PsA

Psoriatic arthritis diagnosis by a rheumatologist within a year of symptom onset improved long-term clinical outcomes, a study showed.

MedScape 18 March at 05.55 AM

No Rise in Cancer Risk With Non-TNF Inhibitor bDMARDs in RA

Non-TNF inhibitor biologic disease-modifying antirheumatic drugs did not appear to increase the risk for cancer in patients with RA in a real-world cohort study.

MedScape 18 March at 04.17 AM

Rheum Workforce May Have Grown, But It's Still Not Enough

The US rheumatology workforce grew by more than 20% from 2009 to 2019, according to new research, but even if this growth continued, it would not be enough to meet the increasing demand.

MedScape 18 March at 03.39 AM

Hyperuricemia Subtypes in Gout Show Distinct Traits

The distinct biologic features of different hyperuricemia subtypes call for the development of tailored, subtype-dependent, genetics-based therapies for gout or hyperuricemia.

MedScape 15 March at 05.21 AM

AI in Rheumatology: Current and Future Roles

AI brings opportunities to improve workflow, make writing and certain tasks easier, and facilitate drug development, experts said at the Rheumatology Winter Clinical Symposium.

HealthDay 14 March at 09.38 PM

Rheumatology Workforce Increased 20 Percent From 2009 to 2019

The overall number of clinically active rheumatology providers grew more than 20 percent during the last decade, according to a study published online Feb. 25 in&nbsp;Arthritis &amp; Rheumatology.Melissa L. Mannion, M.D., from University of Alabama at Birmingham, and colleagues assessed change in rheumatology providers over time and

HealthDay 14 March at 12.04 PM

HHS Opens Investigation Into UnitedHealth Cyberattack

Following a cyberattack on one of the nation's largest health insurers that's thrown health care payments into disarray and likely exposed reams of private patient data, the U.S. Department of Health and Human Services said Wednesday it has begun an investigation into the incident.In a&nbsp;<a href="https://www.hhs.gov/about/news/2024/03/13/h

HealthDay 13 March at 12.05 PM

Cyberattack Leaves Health Care Providers Reeling Weeks Later

Following a cyberattack on the largest health insurer in the United States last month, health care providers continue to scramble as insurance payments and prescription orders continue to be disrupted and physicians lose an estimated $100 million a day.That <a href="https://www.ama-assn.org/press-center/press-releases/cyberattack-jeopardizes

MedScape 11 March at 07.14 AM

Leflunomide: An Overlooked Drug for Your Treatment Toolkit?

Overlooked in the biologic era, it still has a place.

MedScape 11 March at 05.09 AM

RA Outcomes Worsened by Depression and Anxiety

Patients with anxiety or depression were less likely to achieve low disease activity and improve their symptoms compared with those without these mental health conditions.

MedScape 11 March at 01.18 AM

Safe GC Tapering in Lupus: Reducing Flares, Damage

Cautious tapering of glucocorticoids might be feasible even in serologically active clinically quiescent patients with systemic lupus erythematosus.

MedScape 07 March at 12.49 PM

FDA Approves Second Tocilizumab Biosimilar

Tocilizumab-aazg (Tyenne) is approved in both intravenous and subcutaneous formulations.

MedScape 07 March at 07.04 AM

2023's Top SpA Studies Address IBD, Residual Pain, and More

Dr Eric Ruderman discussed IBD screening and treatment, managing residual pain, spondyloarthritis incidence by sex, withdrawing and extending biologics, and prospects for future treatments.

MedScape 07 March at 06.53 AM

Risk for Rheumatic Disease May Rise After COVID

While previous studies had identified a link between COVID-19 infection and greater risk for autoimmune disease, a new study is perhaps the largest and most robust to date to show an association.

MedScape 06 March at 12.22 PM

FDA Approves First Denosumab Biosimilar

Denosumab-bddz was also granted interchangeability status, which allows the biosimilar to subsitute for the reference product without involving the prescriber (according to state law).

HealthDay 05 March at 04.45 PM

Risk for Autoimmune Inflammatory Rheumatic Disease Increased After SARS-CoV-2

Patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have an increased risk for incident autoimmune inflammatory rheumatic disease (AIRD) compared with matched patients with influenza infection or uninfected controls, according to a study published online March 5 in the Annals of Internal Medicine.Min Se

MedScape 04 March at 06.09 AM

GLP-1 Agonists and SGLT2 Inhibitors Do Not Increase Autoimmune Risk

Patients with type 2 diabetes prescribed GLP-1 receptor agonists or SGLT2 inhibitors did not have a greater risk of developing autoimmune disease than those prescribed DPP-4 inhibitors.

HealthDay 01 March at 04.54 PM

Prevalence of Arthritis in U.S. Adults 18.9 Percent in 2022

The age-adjusted prevalence of adults with arthritis was 18.9 percent in 2022 in the United States, according to a February data brief published by the National Center for Health Statistics.Nazik Elgaddal, from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from the 2022 National Health Interview Sur

MedScape 01 March at 05.26 AM

Generic SpA Screening Tool Needed Across Comorbid Diseases

A comparison of screening tools for SpA in conditions that commonly co-occur with the disease revealed few screening tool options for patients with uveitis or IBD, compared with psoriasis.

MedScape 28 February at 11.37 PM

ME/CFS Experts Express 'Dismay' at Aspects of NIH Study

In a statement, the physicians criticize use of the term "effort preference" and a lack of emphasis on the hallmark symptom of post-exertional malaise.

HealthDay 28 February at 04.33 PM

Sinusitis Linked to Increased Risk for Subsequent Rheumatic Disease

A history of sinusitis is associated with an increased incidence of rheumatic disease, according to a study published online Feb. 27 in RMD Open.Vanessa L. Kronzer, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a population-based case-control study involving individuals meeting classification criteria f

MedScape 28 February at 05.00 AM

Six Biomarkers Could Help Predict Cardiovascular Risk in RA

Adding these biomarkers to clinical variables better predicted increases in arterial inflammation than clinical indices such as the Framingham Risk Score.

MedScape 27 February at 04.08 AM

Gout Increases the Risk for a Wide Range of CVDs

Women with gout had a higher risk for CVD than men, and younger adults had a more pronounced risk than controls.

MedScape 26 February at 11.08 AM

FDA OKs 10th Humira Biosimilar, Interchangeability Included

It is the tenth adalimumab biosimilar approved by the regulatory agency.

MedScape 26 February at 11.08 AM

FDA OKs First Interchangeable Humira Biosimilar

It is the tenth adalimumab biosimilar approved by the regulatory agency.

MedScape 26 February at 05.20 AM

Can Microbiome Shifts Predict DMARD Response in RA?

An observational study in the United Kingdom found that patients with RA who started taking antirheumatic drugs had changes in their microbiome after 6 and 12 weeks.

MedScape 25 February at 11.49 PM

Long-Term Ixekizumab Use Shows Solid Safety Data

Final safety results from 25 randomized clinical trials were consistent with previous reports at up to 6 years' follow-up.

HealthDay 23 February at 11.30 PM

Level of Burnout Higher for Women in Health Care Occupations

Women in health care occupations endure a significantly higher level of stress and burnout than men, according to a study published online Feb. 21 in Global Advances in Integrative Medicine and Health.Viktoriya Karakcheyeva, M.D., from the George Washington University School of Medicine and Health Sciences in Washington, D.C., and colle

HealthDay 23 February at 04.45 PM

Therapeutic Intervention Feasible for Preventing Rheumatoid Arthritis in Patients at Risk

Therapeutic intervention with abatacept is feasible for patients at risk for rheumatoid arthritis, according to a study published online Feb. 13 in The Lancet.Andrew P. Cope, M.D., from King's College London, and colleagues conducted a multicenter trial involving patients at risk for rheumatoid arthritis with serum antibodies to citrull

MedScape 23 February at 01.52 AM

Diagnosing Infection in Tocilizumab Users: What's Helpful?

Area under the curve for routine biomarkers distinguished infected and noninfected adults with inflammatory diseases.

HealthDay 22 February at 12.17 PM

Jill Biden Announces $100 Million for Research on Women's Health

First Lady Jill Biden on Wednesday announced $100 million in federal funding to fuel research into women's health.“We will build a health care system that puts women and their lived experiences at its center,” Biden said in a White House <a href="https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/02/21/remarks-as-prepared-for-deliv

MedScape 22 February at 04.10 AM

Prognosis of Polyarteritis Nodosa: What Are the Predictors?

Constitutional symptoms were significantly more common in systemic vs cutaneous disease.

MedScape 22 February at 12.00 AM

'Deep Phenotyping' Identifies Abnormalities in ME/CFS

New research from the National Institutes of Health identified "clear objective changes" in people with postinfectious myalgic encephalomyelitis/chronic fatigue syndrome.

HealthDay 21 February at 10.28 PM

CAR T-Cell Therapy Feasible, Safe for Autoimmune Diseases

CD19 chimeric antigen receptor (CAR) T-cell therapy seems feasible, safe, and efficacious for patients with different autoimmune diseases, according to a study published in the Feb. 22 issue of the New England Journal of Medicine.Fabian Müller, M.D., from the Friedrich-Alexander University Erlangen-Nürnberg in Germany, and colleagues

HealthDay 21 February at 01.45 PM

This Election Year, Health Care Costs Top Voter Concerns: Poll

Unexpected medical bills and high health care costs are dominating an election where kitchen table economic problems weigh heavily on voter’s minds, a new KFF poll has found.Voters struggling to pay their monthly bills are most eager to hear presidential candidates talk about economic and health care issues, according to the latest KFF Health

MedScape 21 February at 01.40 AM

Cushing Remission After Surgery May Raise Autoimmune Risk

The findings suggested the need for closer postsurgical monitoring of patients with a family history of autoimmune disease.

HealthDay 16 February at 04.38 PM

Acupuncture Linked to Lower Incidence of Ischemic Stroke in RA

For patients with rheumatoid arthritis (RA), the risk for ischemic stroke is lower for those receiving acupuncture, according to a study published online Feb. 13 in BMJ Open.Chia-Yu Huang, from Taichung Tzu Chi Hospital in Taiwan, and colleagues conducted a propensity score-matched cohort study involving 23,226 patients with newly diagn

MedScape 15 February at 05.51 AM

Inflammatory Arthritis Has Big Impact on Systemic Sclerosis

In patients with SSc, the presence of inflammatory arthritis is significantly associated with diffuse disease, musculoskeletal manifestations, myositis, and sicca.

MedScape 14 February at 05.49 AM

Exercising With Osteoarthritis: Five Things to Know

Medscape Medical News spoke with osteoarthritis experts on the ideal amount of exercise for patients, available resources, and how to motivate patients to move more.

HealthDay 12 February at 04.17 PM

Link Between Inflammatory Disease, Adverse Pregnancy Outcomes Varies

The association between immune-mediated inflammatory diseases (IMIDs) and adverse pregnancy outcomes varies with the nature of IMID and the presence of comorbidities, according to a study published online Feb. 1 in eClinicalMedicine.Yeon Mi Hwang, from the Institute for Systems Biology in Seattle, and colleagues conducted a retrospectiv

MedScape 07 February at 06.17 PM

Patients With Stable Lupus May Be Safely Weaned Off MMF

Rates of significant disease reactivation were similar more than 1 year after randomization for patients assigned to mycophenolate mofetil (MMF) withdrawal or MMF maintenance.

MedScape 07 February at 06.41 AM

Comorbidities Weigh Heavily in Autoimmune Pregnancy Outcomes

After controlling for other chronic conditions, certain immune-mediated inflammatory diseases were not associated with an increased risk for poor pregnancy outcomes.

MedScape 07 February at 12.31 AM

Preventing Autoimmune Diseases: New Vit. D, Omega-3 Findings

Omega-3 fatty acid supplements prevented autoimmune diseases for 2 years after cessation, but vitamin D's effects tapered off, suggesting that continuous dosing is warranted.

MedScape 06 February at 12.06 PM

Target These Serum Urate Levels to Prevent Gout Flares

The findings "support the value of target serum urate levels in gout flare prevention in primary care, where most gout patients are treated."

MedScape 06 February at 05.10 AM

Pseudogout Nearly Doubles Fracture Risk

Patients with CPPD disease were 80% more likely to experience a fracture, compared with those without the disease, with wrist fractures driving this trend.

HealthDay 05 February at 11.45 PM

Price of Prescription Drugs Almost Threefold Higher in the United States

Prescription drug prices are nearly three times higher in the United States than in other countries, according to a report published by the RAND Corporation.Andrew W. Mulcahy, and colleagues from the RAND Corporation, compared the prices of different categories of drug products, including brand-name originator drugs, unbranded generic drugs, biol

MedScape 05 February at 04.37 AM

Utility of NSAID Response Questioned for Longstanding AxSpA

Positive response to NSAIDs was not a distinguishing feature between patients with longstanding axial spondyloarthritis (axSpA) and patients with non-axSpA chronic back pain.

MedScape 02 February at 06.20 AM

Proinflammatory Diet May Prompt Worse Pain Course in Knee OA

Long-term data suggested a role of diet in persistence of knee pain but not structural changes.

HealthDay 29 January at 10.54 PM

Practitioner Empathy Interventions Can Improve Patient Satisfaction

Health care practitioner empathy interventions seem to improve patient satisfaction, but inadequate reporting hinders the ability to draw definitive conclusions relating to the overall effect size, according to a review published online Jan. 30 in the Annals of Internal Medicine.Leila Keshtkar, Ph.D., from the University of Leicester in

MedScape 26 January at 07.16 AM

What Is the Clinical Course of Low Back Pain?

If low back pain lasts for more than 3 months, then it is less likely to improve significantly over time, new data suggest.

MedScape 25 January at 09.58 AM

Higher Male Fertility Rate Seen With Inflammatory Arthritis

In a population-based study, male patients with inflammatory joint disease had more children and were less likely to be childless than healthy comparator individuals.

HealthDay 24 January at 04.57 PM

Ten Variants Suggest Link to Surgical, Nonsurgical Rhizarthrosis

Ten variants have been identified that are suggestive of an association with surgical or nonsurgical rhizarthrosis, according to a study published online Jan. 24 in the Journal of Orthopedic Research.Cecilie Henkel, Ph.D., from Copenhagen University Hospital Hvidovre in Denmark, and colleagues conducted a case-control genome-wide ass

HealthDay 24 January at 04.24 PM

Men With Inflammatory Joint Diseases Seem to Have More Children

Men with inflammatory joint diseases (IJDs) have a higher number of children and are less likely to be childless, according to a study published online Jan. 22 in the Annals of Rheumatic Disease.Gudrun David Sigmo, from Stavanger University Hospital in Norway, and colleagues conducted a nationwide, population-based, retrospective coh

MedScape 24 January at 07.11 AM

Progression to Radiographic SpA: Risk Factors and Timeframe

A 5-year study found a mean time to radiographic progression of 2.4 years in patients with newly diagnosed axial spondyloarthritis.

MedScape 24 January at 06.39 AM

RA Disease Activity Assessed Too Little After Starting TNFi

More than half of patients with RA lacked baseline assessment of disease when they began TNFi therapy.

MedScape 24 January at 03.04 AM

Need a Rheumatology APP? Here's What to Consider

Advanced practice providers are a cornerstone of strategies to address the shortage of rheumatologists, and here are considerations to keep in mind when hiring, training, and retaining them.

HealthDay 22 January at 10.13 PM

Older Adults Average 20.7 Total Health Care Contact Days a Year

Older adults have a mean of 20.7 total health care contact days per year, according to a study published online Jan. 23 in the Annals of Internal Medicine.Ishani Ganguli, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and colleagues characterized health care contact days among community-dwelling adults aged 65 years and olde

HealthDay 19 January at 05.24 PM

Bidirectional Link ID'd for Autoimmune Disease, Perinatal Depression

There is a bidirectional association between autoimmune disease (AD) and perinatal depression (PND), according to a study published online Jan. 9 in Molecular Psychiatry.Emma Bränn, from the Karolinska Institutet in Stockholm, and colleagues examined the bidirectional association between PND and AD using nationwide Swedish population an

HealthDay 17 January at 04.58 PM

Inflammation, Poverty Have Synergistic Effect on Mortality

There is a potential synergistic effect for inflammation and living in poverty with increased mortality risk for adults, according to a study published online Jan. 16 in Frontiers in Medicine.Arch G. Mainous III, Ph.D., from the University of Florida in Gainesville, and colleagues examined whether there is a synergistic effect of the

MedScape 15 January at 05.31 AM

Genetic Screening and Targeted Treatment Halt Paget Disease

A single infusion of zoledronic acid substantially reduced existing bone lesions and biochemical markers of bone turnover over 7 years.

MedScape 15 January at 04.28 AM

Two-Way Link Between Autoimmune Disease/Perinatal Depression

Study found women with autoimmune disease were 30% more likely to have perinatal depression. Risk was also 30% higher for the reverse scenario.

MedScape 15 January at 02.26 AM

Remote Diet, Exercise Intervention for RA Proves Beneficial

An exercise and diet program using videoconferencing and YouTube reduced cardiovascular risk and improved patient-reported outcomes and disease activity.

MedScape 12 January at 03.49 AM

Tool Uses Genetics to Diagnose Early Inflammatory Arthritis

The tool may aid in accelerating accurate diagnosis and getting patients on the right treatments earlier.

HealthDay 11 January at 09.34 PM

Affordable Care Act Sees Record Number of Americans Signing Up

With only days left before open enrollment closes, the Biden administration announced Wednesday that 20 million Americans have already signed up for health insurance under the Affordable Care Act."Today, we hit a major milestone in lowering costs and ensuring all Americans have access to quality, affordable health care. With six days left to s

HealthDay 11 January at 04.48 PM

CDC: 5.7 Percent of Adults Lacked Reliable Transportation in 2022

In 2022, 5.7 percent of adults reported lacking reliable transportation for daily living, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.Amanda E. Ng, Ph.D., M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues u

HealthDay 10 January at 04.24 PM

Hormonal, Reproductive Factors Linked to RA Risk Among Women

Certain hormonal and reproductive factors are associated with an increased risk for rheumatoid arthritis (RA) among women, according to a study published online Jan. 9 in RMD Open.Ling-Qiong Jiang, from the Anhui Medical University School of Public Health in Hefei, China, and colleagues collected data on hormonal and reproductive fac

MedScape 10 January at 06.41 AM

Axial Spondyloarthritis: More Than a Pain in the Back

Axial spondyloarthritis is characterized by chronic inflammatory back pain, but there are related conditions that may need to be managed alongside.

MedScape 10 January at 06.13 AM

Resistance Training Beneficial in PsA Regardless of Format

Two types of strength training were associated with similar improvements in function and disease activity in a randomized trial of patients with psoriatic arthritis.

MedScape 10 January at 12.34 AM

Severe RA: Exercise Therapy Improves Functional Limitations

An intervention including goal setting, active exercise, and education was tailored to functional limitations.

MedScape 08 January at 08.16 AM

SGLT2 Inhibitors Begin to Show Potential in Rheumatology

Sodium-glucose cotransporter-2 inhibitors are not approved to treat gout, lupus, or lupus nephritis, but clinicians are uncovering signs of benefits in these conditions.

HealthDay 08 January at 04.59 AM

Suicide Risk Increased for Some U.S. Health Care Workers

Registered nurses, health technicians, and health care support workers have an increased risk for suicide compared with non-health care workers, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association.Mark Olfson, M.D., M.P.H., from Columbia University and the New York State Psychiatric

MedScape 08 January at 12.49 AM

Intensive Weight Loss Does Not Ease Gout Symptoms

Researchers found an association between weight loss and a corresponding reduction in serum urate, but more weight loss did not result in positive changes in pain or fatigue.

HealthDay 07 January at 04.59 AM

U.S. Safety-Net Providers Report Moral Distress in Early Pandemic

Moral distress during the first nine months of the pandemic was reported by a majority of clinicians working in U.S. safety net practices, according to a study published online Aug. 25 in BMJ Open.Donald E. Pathman, M.D., M.P.H., from the University of North Carolina at Chapel Hill, and colleagues examined causes and levels of moral dis

HealthDay 07 January at 04.59 AM

Child Care Stress Affects Health, Work of U.S. HCWs During Pandemic

Child care stress (CCS) during the pandemic is associated with anxiety, depression, burnout, intent to reduce hours, and intent to leave among health care workers (HCWs), according to a study published online July 18 in JAMA Network Open.Elizabeth M. Harry, M.D., from the University of Colorado in Aurora, and colleagues assessed whether

HealthDay 07 January at 04.59 AM

COVID-19 Pandemic Tied to Burnout in Health Care Professionals

The COVID-19 pandemic is associated with higher burnout among health care professionals (HCPs), particularly patient-facing HCPs, according to a study published online Sept. 27 in BJPsych Open.Vikas Kapil, M.B.B.S., Ph.D., from the Queen Mary University of London, and colleagues longitudinally examined mental health in 1,574 HCPs vers

HealthDay 04 January at 04.59 AM

Stress-Management Interventions May Aid Health Care Workers

Stress-management interventions may help individual health care workers over the short term, according to research published online May 12 in the Cochrane Database of Systematic Reviews.Sietske J. Tamminga, Ph.D., from the University of Amsterdam, and colleagues conducted a systematic review to evaluate the effectiveness of stress-red

MedScape 03 January at 07.10 AM

Tips for Managing Axial Spondyloarthritis in Primary Care

The rheumatology consultation may have been requested, but how can primary care practitioners help their patients who have suspected axial spondyloarthritis in the meantime?

HealthDay 30 December at 04.59 AM

Model Predicts New Psoriatic Arthritis in People With Psoriasis

The development of psoriatic arthritis (PsA) can be predicted with reasonable accuracy for psoriasis patients, according to a study published online Aug. 9 in Arthritis & Rheumatology.Lihi Eder, M.D., Ph.D., from University of Toronto, and colleagues developed a risk prediction model (<a href="http://sharpmindtill120.x10host.co

HealthDay 27 December at 03.42 PM

Disease-Modifying Antirheumatic Drugs May Cut Incidence of Autoimmune Thyroid Disease

Disease-modifying antirheumatic drugs (DMARDs) might prevent incidence of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA), according to a study recently published in the&nbsp;Journal of Internal Medicine.Kristin Waldenlind, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined

HealthDay 26 December at 10.37 PM

More Than Half of U.S. Medical Interns Experience Sexual Harassment

More than half of U.S. medical interns report experiencing sexual harassment, according to a research letter published online Dec. 26 in&nbsp;JAMA Network Open.Elizabeth M. Viglianti, M.D., from the University of Michigan in Ann Arbor, and colleagues investigated possible institutional variation in experiences of sexual harassment amon

HealthDay 22 December at 04.02 PM

494 Million People Had Other Musculoskeletal Disorders Globally in 2020

Globally, 494 million people had other musculoskeletal disorders in 2020, with a 115 percent increase projected to 2050, according to a study published online in the November issue of The Lancet Rheumatology.Tiffany K. Gill, Ph.D., from the University of Adelaide in Australia, and colleagues estimated the prevalence of other musculoskel

MedScape 21 December at 08.09 AM

New Research Aims to Unravel Both ME/CFS and Long COVID

A 2-day research conference sponsored by the US National Institutes of Health highlighted research that points to mechanisms that suggest potentially "druggable" pathways.

MedScape 21 December at 07.38 AM

Low-Dose Naltrexone Researcher Disputes Study Negativity

Neuroinflammation expert Jarred Younger, PhD, disputes commentary calling for clinicians to stop prescribing the off-label compounded medication to reduce pain in people with fibromyalgia.

MedScape 21 December at 06.53 AM

When's Best to Re-dose Rituximab After Vasculitis Remission?

A single-center study found that using B-cell levels to determine when to infuse rituximab reduced relapses in patients antineutrophil cytoplasmic antibody vasculitis.

MedScape 21 December at 03.53 AM

A New Test Could Save Arthritis Patients Time, Money, Pain

Stories of chronic pain, drug-hopping, and insurance meddling are all too common among patients with rheumatoid arthritis. Precision medicine offers new hope.

HealthDay 20 December at 10.02 PM

Burnout, Lack of Fulfillment Linked to Physician Intention to Leave

Burnout, lack of professional fulfillment, and other well-being-linked factors are associated with intention to leave (ITL) among physicians, according to a study published online Dec. 15 in JAMA Network Open.Jennifer A. Ligibel, M.D., from the Dana-Farber Cancer Institute in Boston, and colleagues describe the prevalence of burnout,

MedScape 19 December at 06.02 AM

Novel Solutions Needed to Boost Pediatric Rheum Recruitment

Projections suggest that by 2030, demand for pediatric rheumatologists in the United States will exceed supply by about 77%.

HealthDay 15 December at 12.00 AM

More Senior Physicians See Fewer Underserved Patients

Senior physicians treat fewer traditionally underserved patients than their junior colleagues within the same practices, according to a research letter published online Dec. 13 in&nbsp;JAMA Network Open.Hannah T. Neprash, Ph.D., from University of Minnesota School of Public Health in Minneapolis, and colleagues examined the associatio

HealthDay 14 December at 05.00 PM

Blacks More Likely to Have Disseminated Manifestations of Lyme Disease

Black patients are more likely to be diagnosed with disseminated manifestations of Lyme disease (LD) and experience longer time to appropriate treatment, according to a research letter published online Dec. 12 in JAMA Network Open.Samuel J. Starke, M.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues

MedScape 13 December at 06.30 PM

Researchers Better Understand RA-Associated ILD

Clinically significant ILD is believed to occur in 5%-10% of patients with RA, but robust data are lacking on how to best predict which patients face the highest risk for RA-associated ILD.

HealthDay 12 December at 04.05 PM

ChatGPT Shows Poor Performance in Answering Drug-Related Questions

ChatGPT provided no response or incomplete or wrong answers to nearly three-quarters of drug-related questions reviewed by pharmacists, according to a study presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting, held from Dec. 3 to 7 in Anaheim, California.Sara Grossman, Pharm.D., from Long Island University in

MedScape 11 December at 09.49 AM

Antiobesity Drugs in OA: Slow, Moderate Approach Deemed Best

Rapid weight loss with antiobesity drugs had no significant impact on reduced mortality in a population-based study of more than 6000 adults with knee or hip osteoarthritis.

MedScape 11 December at 07.32 AM

Young Rheum Patients Report Gaps in Sexual Health Counseling

In a new survey, only half of teens and young adults on teratogens said they had been counseled on the reproductive risk of for their medications.

MedScape 11 December at 07.01 AM

Low-Dose Naltrexone Falls Short for Fibromyalgia

Despite off-label use of naltrexone by some patients with fibromyalgia in clinical practice, data from a randomized trial showed no pain relief advantage with the drug over placebo.

HealthDay 08 December at 05.04 PM

CDC: Chronic Fatigue Syndrome Prevalence 1.3 Percent in 2021 to 2022

The prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in the United States in 2021 to 2022 was 1.3 percent, according to a December data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.Anjel Vahratian, Ph.D., M.P.H., from the National Center for Health Statistics

HealthDay 07 December at 10.40 PM

White House Looks to Curb Big Pharma's Sky-High Drug Prices

In a push for lower drug prices, the Biden administration is warning pharmaceutical companies that it might use its authority to cancel patent protections if a medication is too expensive. Federal law allows the government to grant patent licenses if taxpayer dollars were used in the development of inventions -- including drugs.In a <a href="ht

HealthDay 07 December at 04.41 PM

Slow-to-Moderate Weight Loss Linked to Lower Mortality in Knee, Hip OA

For individuals with overweight or obesity and knee or hip osteoarthritis (OA), a slow-to-moderate, but not a fast, rate of weight loss is associated with a reduced risk for all-cause mortality, according to a study published online Dec. 6 in Arthritis &amp; Rheumatology.Jie Wei, Ph.D., from Xiangya Hospital in Changsha, China, and col

HealthDay 06 December at 10.59 PM

Many Patients of Color Expect and Prepare for Unfair Health Care

Minorities often feel a deep sense of dread before doctor appointments, and some even try to dress especially well for their visit to try and ward off the possibility they will face insults or unfair care. According to a new poll conducted by hea

HealthDay 01 December at 05.06 PM

Four JAK Inhibitors Have Comparable Efficacy, Safety for RA

For patients with rheumatoid arthritis, the efficacy and safety of four Janus kinase (JAK) inhibitors is comparable, according to a study published online Nov. 1 in Rheumatology.Shinya Hayashi, M.D., from the Kobe University Graduate School of Medicine in Japan, and colleagues conducted a multicenter, retrospective study comparing the ef

HealthDay 29 November at 04.55 PM

CDC: 2021 to 2022 Saw Increase in U.S. Life Expectancy

From 2021 to 2022, there was an increase in life expectancy, which was seen for both sexes and across racial/ethnic groups, according to a November Vital Statistics Rapid Release report, a publication from the U.S. Centers for Disease Control and Prevention.Elizabeth Arias, Ph.D., from the National Center for Health Statistics in Hya

MedScape 29 November at 03.46 PM

Rheumatology Fills Over 97% of Fellowship Programs for 2024

Adult rheumatology remains popular but pediatric rheumatology continues to be less successful, filling only 55% of programs.

MedScape 29 November at 02.03 PM

COVID Vax T-Cell Responses Help B-Cell–Deficient Patients

The findings demonstrate how vaccine-induced T-cell responses could potentially reduce COVID-19 severity, the authors write.

MedScape 29 November at 01.20 PM

Rheumatology Patients Prefer Office Visits to Telemedicine

Despite relatively high approval rates overall, patient satisfaction was lower among those treated via telemedicine at two tertiary medical centers.

HealthDay 28 November at 04.57 PM

Fourth COVID-19 Shot Beneficial in Patients With Autoimmune Rheumatic Diseases

For patients with systemic autoimmune rheumatic diseases using disease-modifying antirheumatic drugs (DMARDs), receiving a fourth COVID-19 mRNA vaccine reduces the risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online Nov. 15 in The Lancet Rheumatology.Jennifer S. Hanberg

MedScape 28 November at 01.30 PM

Conditional Recommendations Rule in New SARD ILD Guidelines

In spring 2024, the ACR is expected to release guidelines to help inform the screening, monitoring, and treatment of interstitial lung disease (ILD) in people with SARDs.

MedScape 28 November at 01.19 PM

Telitacicept Shows Efficacy, Safety in MTX-Resistant RA

Telitacicept is a recombinant fusion protein that aims to target and neutralize B lymphocyte stimulator and a proliferation-inducing ligand (APRIL), both of which are linked to autoimmunity.

MedScape 28 November at 01.11 PM

Abatacept Slows Progression to RA, Phase 2b Trial Finds

The study was conducted at 28 sites in the United Kingdom and three in the Netherlands.

MedScape 27 November at 07.57 PM

Benralizumab Proves Noninferior to Mepolizumab for EGPA

Treatment with benralizumab (Fasenra) achieved remission at 36 and 48 weeks at rates similar to those of mepolizumab (Nucala) in a head-to-head phase 3 trial of the two drugs.

MedScape 27 November at 02.04 PM

Methotrexate Carries Higher Risk for Older CKD Patients

Adverse event data showed an increased risk of myelosuppression, sepsis, pneumotoxic effects, or hepatotoxic effects.

MedScape 21 November at 07.25 PM

Risks Quantified in Medically Optimized Pregnancy With Lupus

Patients who were not medically optimized for pregnancy were three times more likely to experience preterm birth and preeclampsia.

MedScape 21 November at 03.22 PM

Telemedicine Offers Solution for No-Show Appointments

Converting these missed appointments to telemedicine visits resulted in more than 250 additional hours of patient care as well as a moderate reduction in lost revenue.

MedScape 20 November at 06.52 PM

IV Secukinumab Trials Hit Primary Endpoints in PsA, AxSpA

Two phase 3 trials of the recently approved IV formulation of secukinumab showed its efficacy vs placebo in treating psoriatic arthritis and axial spondyloarthritis.

MedScape 20 November at 03.14 PM

Novel Blood Test Can Detect Rheumatoid Arthritis

An experimental assay detects epigenetic features within the unique patterns and sizes of cell-free DNA found in blood, but is it better than clinical diagnostics?

HealthDay 16 November at 04.55 PM

Obinutuzumab Preserves Kidney Function in Lupus Nephritis

For patients with lupus nephritis (LN), obinutuzumab treatment results in better preservation of kidney function and prevention of LN flares, according to a study published online Nov. 10 in Arthritis &amp; Rheumatology.Brad H. Rovin, M.D., of The Ohio State University Wexner Medical Center in Columbus, and colleagues examined whether

MedScape 16 November at 04.45 PM

Study Takes Fine-Grained Look at MACE Risk With GCs in RA

'Up to half of RA patients in the United States use long-term glucocorticoids despite previous work suggesting they increase MACE in a dose-dependent way.'

MedScape 16 November at 12.04 PM

Split-Dose Methotrexate Speeds RA Response Over Single Dose

Compared with a single dose, more patients in the split-dose group had improved disease activity at 16 weeks, and fewer needed additional DMARDs, but the effect was not found at 24 weeks.

MedScape 15 November at 06.03 PM

First Referral Guide Issued for Axial Spondyloarthritis

The draft recommendations are a 'good first step,' but more awareness around axial spondyloarthritis in the non-rheumatology community is also needed to improve diagnosis, one expert said.

MedScape 15 November at 11.34 AM

Apremilast Beats Placebo in Early PsA Affecting Few Joints

Oligoarticular PsA can significantly affect quality of life even though few joints are affected, and there's a lack of relevant clinical data to guide treatment.

MedScape 14 November at 08.21 PM

Vasculitis Gives Higher Risk for Adverse Pregnancy Outcomes

&quot;This study should help inform our family planning conversations with our vasculitis patients,&quot; Lindsay S. Lally, MD, said.

HealthDay 14 November at 04.19 PM

Male, Female Veterans Have Increased Prevalence of Arthritis

Male and female veterans have a higher prevalence of arthritis than nonveterans, according to research published in the Nov. 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Elizabeth A. Fallon, Ph.D., from the CDC in Atlanta, and colleagues analyzed pooled data from the 2017 to 2021

MedScape 14 November at 11.54 AM

TNF Inhibitors May Be OK for Treating RA-ILD

Efficacy, safety findings for the use of TNF inhibitors vs other biologic disease-modifying antirheumatic drugs in treating RA-ILD contrast with those of some smaller observational studies.

MedScape 14 November at 06.31 AM

CPPD Nomenclature Is Sore Subject for Gout Group

Since 2011, the nomenclature guidelines have been cited hundreds of times, but a new report finds that the medical literature mostly hasn’t followed the recommendations.

MedScape 13 November at 06.41 PM

TNF Blockers Not Associated With Poorer Pregnancy Outcomes

Patients with rheumatic disease who continued TNF blockers during their pregnancy did not have an increased risk of worse fetal and maternal outcomes and had a lower risk of severe infection.

HealthDay 13 November at 05.02 PM

ACR: Incidence of Atrioventricular Block Increased With High Levels of Anti-SSA/Ro Antibodies

High levels of anti-SSA/Ro antibodies are associated with an increased incidence of fetal atrioventricular block (AVB), according to a study published online Nov. 10 in Arthritis &amp; Rheumatology to coincide with the annual meeting of the American College of Rheumatology, held from Nov. 10 to 15 in San Diego.Jill P. Buyon, M.D., from

MedScape 13 November at 12.42 PM

Studies Support Early Use of ULT, Warn of PAD

A new analysis suggests that it may not be necessary to delay urate-lowering therapy in gout flares, and a study warns of the potential heightened risk for peripheral arterial disease in gout.

MedScape 12 November at 11.29 PM

Pregnancy in Rheumatic Disease Quadruples CVE Risk

Pregnant patients with lupus and concomitant APS had an 18-fold higher risk for a cardiovascular event during and up to 6 weeks postpartum than did pregnant individuals without these conditions.

MedScape 12 November at 02.54 PM

Pregnancies With Low Anti-SSA/Ro: Forgo Heart Monitoring?

The ongoing prospective multicenter trial is the largest of its kind.

MedScape 10 November at 07.17 PM

Short Steroid Taper Tested With Tocilizumab for GCA

Results from a pilot study examining a shortened prednisone taper of 8 weeks' length rather than 26 weeks suggest it may be possible to reduce patients' duration of exposure to glucocorticoids.

MedScape 10 November at 08.01 AM

Obinutuzumab Promotes Renal Preservation in Lupus Nephritis

A post hoc analysis of the NOBILITY trial showed improved outcomes for patients taking obinutuzumab (Gazyva) compared with placebo.

HealthDay 08 November at 04.38 PM

Oral Contraceptives May Protect Against Rheumatoid Arthritis

Oral contraceptive use appears to protect against rheumatoid arthritis (RA), while menopausal hormone therapy (MHT) use may increase the risk for late-onset RA, according to a study published online Sept. 29 in&nbsp;Rheumatology.&nbsp;Fatemeh Hadizadeh, M.D., Ph.D., from Uppsala University in Sweden, and colleagues estimated the effec

HealthDay 06 November at 04.52 PM

Methotrexate Reduces Pain in Hand Osteoarthritis With Synovitis

For patients with hand osteoarthritis and synovitis, methotrexate has a potentially clinically meaningful effect on reducing pain, with no increase in adverse events, according to a study published online Oct. 12 in The Lancet.Yuanyuan Wang, Ph.D., from Monash University in Melbourne, Australia, and colleagues conducted a randomized, pla

HealthDay 03 November at 11.00 PM

Critics Slam Updated Infection Control Recommendations for Hospitals

Advisors to the U.S. Centers for Disease Control and Prevention are expected to approve new draft guidelines for hospital infection control this week, the first update since 2007.But health care workers worry whether the guidelines, which suggest that surgical masks are as good as N-95 masks at preventing the spread of respiratory infections duri

MedScape 02 November at 06.29 PM

JAK Inhibitor Effects in RA Confirmed in Real-World Study

The safety and efficacy of tofacitinib, baricitinib, peficitinib, and upadacitinib were similar in a multicenter study of more than 600 adults with rheumatoid arthritis.

MedScape 02 November at 02.37 PM

Antiphospholipid Antibodies Vary by Race in People With SLE

A study of multiple cohorts of patients with systemic lupus erythematosus showed significantly lower prevalence of antiphospholipid antibodies (aPLs) among Black patients.

MedScape 02 November at 02.05 PM

Strength Training Promotes Knee Health, Lowers OA Risk

Adults with a history of strength training were significantly less likely to suffer from knee osteoarthritis and knee pain than were those with no strength training.

MedScape 01 November at 12.15 PM

FDA Approves First Ustekinumab Biosimilar

The drug has also been granted an interchangeability designation and has been approved for six indications.

MedScape 31 October at 05.01 PM

FDA Approves Abatacept for Pediatric Patients With Psoriatic Arthritis

As many as 5% of pediatric patients with juvenile idiopathic arthritis are estimated to have juvenile PsA.