Ketamine No Better for Depression Than Placebo?

No Significant Difference: The study found no significant difference in the reduction of depressive symptoms between patients receiving ketamine and those receiving a placebo during surgery.

Improvement in Both Groups: Both the ketamine and placebo groups showed an improvement in depressive symptoms, which could be due to the patients' expectations of receiving ketamine.

Clinical Response Rates: High rates of clinical response and remission were reported in both groups, with no significant difference attributable to the ketamine treatment.

Hospital Stay Duration: Patients in the ketamine group had a significantly shorter average hospital stay compared to the placebo group.

Limitations and Bias: The study acknowledged limitations, including not measuring participants' expectations beforehand and potential bias in the administration of treatments.