Scientists identify how dietary restriction slows brain aging and increases lifespan

The ScienceDaily article highlights a study identifying the OXR1 gene as crucial in extending lifespan and improving brain health through dietary restriction. This gene's role in aging and brain protection was previously unknown, offering new insights into the benefits of calorie reduction.

Researchers found that dietary restriction affects the retromer protein complex, essential for cellular protein recycling. OXR1 is key to this process, suggesting that diets like intermittent fasting could enhance OXR1 levels, thereby protecting the brain, particularly against neurodegenerative diseases.

The study's findings open possibilities for new therapies targeting age-related brain diseases. Enhancing OXR1 expression in fruit flies extended their lifespan, hinting at similar potential in humans. This underscores the significant impact of diet on health and aging, and the potential of genetic therapies in extending healthy life spans.