Cracking epigenetic inheritance: Biologists discovered the secrets of how gene traits are passed on

• Prof. Zhai's team discovered how DNA copying machinery transfers epigenetic information, vital for gene traits.
• They identified FACT's crucial role in capturing and transferring parental histones during DNA replication.
• Understanding this mechanism offers insights into epigenetic inheritance and potential cancer treatments.
• Their research, published in Nature, sheds light on replication-coupled histone recycling, impacting gene regulation and disease research.
• This breakthrough paves the way for targeted therapeutic interventions in cancer and deeper exploration of epigenetic complexities.