All articles tagged: Diseases, Conditions, Syndromes

Researchers at Germans Trias i Pujol Research Institute (IGTP) and Institut d'Investigació Sanitària Pere Virgili (IISPV) have conducted a review on the therapeutic potential of extracellular vesicles in inflammatory bowel disease. While this approach remains in the early stages of research, ongoing clinical studies for various diseases already support its viability.

The prevalence of suicide is higher among those with epilepsy compared with the general population, according to a study published in the journal Epilepsy & Behavior.

There are bidirectional associations for sleep disorders with chronic kidney disease (CKD), according to a review published in the November issue of Chronic Kidney Journal.

A child in California has tested positive for bird flu, despite having no known contact with infected animals, state officials reported Tuesday.

Researchers at the University of Virginia have made a significant discovery that could change how doctors treat viral infections of the heart. The study, published in Science Advances, reveals that the heart responds to viral infections in one of three distinct ways, offering new insights that may lead to better treatments for people at risk of heart failure. These findings bring new hope for pati

Half of young adult patients treated in emergency departments in three urban hospitals across the country reported experiencing violence either as a victim or aggressor, including firearm violence, in the six months prior to seeking treatment, according to a University of Michigan study.

Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of newborn mortality and morbidity worldwide, and lowering the baby's body temperature—called therapeutic hypothermia—is often used as a treatment.

Microscopic, single-cell differences found in the lungs of COVID-19 patients in Malawi demonstrate the value and importance of cutting-edge infectious disease research in Sub-Saharan Africa.

Fibromyalgia is a chronic disorder characterized by muscle pain throughout the body, fatigue, sleep problems and cognitive difficulties. The condition predominantly affects women, but men can also suffer from it. However, they often do so in silence, as they face cultural, medical and psychological barriers to being taken seriously and receiving treatment.

Patients with symptomatic anemia associated with chronic kidney disease who are on chronic maintenance dialysis can now also receive vadadustat instead of an erythropoiesis-stimulating agent such as darbepoetin.

People with chronic liver disease can be categorized into four distinct risk groups based on the different barriers they face in obtaining outpatient care, barriers that increase their odds of requiring hospitalization, a new UCLA study finds.

Periods can feel like an unwanted guest for many women and gender-diverse people who menstruate, bringing cramps, mood swings and exhaustion.

Disruptions to support services during the COVID-19 pandemic led Australians with disabilities to report significant declines in life satisfaction and mental health, a new study from Flinders University has found.

The World Health Organization has authorized the first mpox vaccine for children, a decision experts hope will help make immunizations more widely available to one of the hardest-hit populations during the ongoing outbreaks of the disease in Congo and elsewhere in Africa.

We live longer and longer, and as we age, a lot of us develop a series of health issues and chronic diseases, including chronic obstructive pulmonary disease (COPD), which is found in around 600 million individuals globally. However, only half of them know they have the disease.

The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.

The U.S. Preventive Services Task Force (USPSTF) recommends early screening for syphilis infection in all pregnant women (grade A recommendation). This recommendation forms the basis of a draft recommendation statement published online Nov. 19.

The United States has reported its first confirmed case of the more contagious form of mpox, formerly known as monkeypox.

Researchers have used artificial intelligence (AI) to analyze patient urine samples and predict when symptoms of chronic obstructive pulmonary disease (COPD) will flare up, according to a study published in ERJ Open Research.

The World Health Organization on Tuesday approved an mpox vaccine from Japanese pharma company KM Biologics for emergency use, the second one to get the agency's seal of approval.

Pakistan detected one more polio case in the restive northwest bordering Afghanistan, raising the country's tally of the infectious disease to 50 cases this year, officials said Wednesday.

In the United States, there are currently more adults living with cerebral palsy than children. Despite this, the Centers for Disease Control and Prevention still label cerebral palsy as "the most common motor disability in childhood."

In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) trigger mild cold-like symptoms. But in infants and seniors, these viruses can cause severe pneumonia and even death.

Meningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS network and led by the Barcelona Institute for Global Health (ISGlobal). The study, published in the Journal of Infection, reveals a high prevalence of drug-resistant bacteria in hospital cases, highlighting the need for earlier suspicion and faster diagnosis and appropriate tre

Researchers at University of Tsukuba have found that the phosphate concentration in proximal tubule fluid, estimated from urine and blood tests, is associated with elevated renal tubular damage markers.

A competitive swimming program developed by University of Queensland researchers for young people with severe cerebral palsy has reversed motor decline associated with the condition.

Respiratory syncytial virus, or RSV, is something many parents know as a cause of bronchiolitis, but others may not have heard of it until recently. RSV causes infections of the lungs and respiratory tract. It's common in children, but it can also infect adults.

The spread of a mosquito in East Africa that thrives in urban areas and is immune to insecticide is fueling a surge in malaria that could reverse decades of progress against the disease, experts say.

Tens of thousands of genetically modified mosquitos are being released every week in Djibouti as the tiny Horn of Africa state experiments with a new weapon against an unprecedented malaria surge.

Medical professionals have long known that the earlier a disease is detected, the higher the chance for a better patient outcome. Now, a multidisciplinary team of Michigan State University researchers, in collaboration with experts from Karolinska Institute and the University of California, Berkeley, has pioneered a way to do just that. The new method takes a deeper look at the proteins in plasma

As whooping cough cases rise in the U.S., a new nasal vaccine developed by Tulane University may hold the key to reducing the spread of the highly contagious respiratory disease.

Researchers from Peking University have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.

Roughly 4% of the population is affected by a congenital brain malformation that has eluded researchers' efforts to find causes and treatments. For the condition, Chiari type-1 malformation, the diagnosis is straightforward: The lower part of the brain, known as the cerebellum, protrudes at least five millimeters through the gap in the skull that connects to the spinal cord.

Researchers at Kennedy Krieger Institute have made significant strides in improving the lives of patients with Tourette syndrome. Their recent publication highlights how behavioral therapies—an approach that teaches patients how to manage certain tics using behavioral strategies—are proving to be the most effective treatment.

Helena Alpkvist from the Infectious Diseases and Dermatology Unit at the Department of Medicine, Huddinge, is defending her thesis titled "Damage-associated molecular patterns and pathogen-associated molecular patterns in severe bacterial infections," on 22 November, 2024. The main supervisor is Kristoffer Strålin (MedH).

The COVID-19 virus spreads via mucus once inside an infected airway, allowing it to reach into the lower lungs, according to a Northwestern Medicine study published in Nature Communications.

As H5N1 bird flu spreads among California dairy herds and southward-migrating birds, health officials announced Friday six more human cases of infection: five in California and one in Oregon — the state's first.

Hepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurological disorders. Little is yet known about how this process works.

The first confirmed case of vertical transmission of Oropouche virus (OROV) has been reported by 23 researchers from eight distinct institutions in Brazil.

A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study. And the findings could spare these children from needing to have a daily injection to boost growth.

Respiratory syncytial virus (RSV) is associated with a considerable burden of hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths among adults, according to a study published online Nov. 13 in JAMA Network Open.

Climate change is responsible for nearly a fifth of the record number of dengue cases worldwide this year, US researchers said on Saturday, seeking to shine a light on how rising temperatures help spread disease.

Health officials said Saturday they have confirmed the first U.S. case of a new form of mpox that was first seen in eastern Congo.

A new UC Davis Health study has uncovered how Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present. The research, published in the Proceedings of the National Academy of Sciences, explains how the pathogen tricks the gut environment to escape the body's natural defenses.

In May, the WHO raised the alarm over the rise in the incidence of sexually transmitted illnesses (STIs) in many regions of the world, currently running at more than a million new cases per day. Among high-income countries, the US has one of the highest prevalence of STIs, and this problem is getting worse. For example, the incidence of chlamydia has more than doubled since 2000, while gonorrhea i

The burden of superficial cutaneous fungal infections (SCFIs) among outpatient visits in the United States is high and increasing, according to a study published online Oct. 30 in the Journal of the American Academy of Dermatology.

A new international study has shed light on the significant burden of post-acute COVID-19 symptoms across North America, Europe and Asia.

Blood stem cells develop through different stages to become fully mature red blood cells. This fundamental biologic process is defined by a series of complex metabolic processes, which are often dysregulated in blood disorders such as sickle cell disease and β-thalassemia.

Dietary zinc deficiency promotes lung infection by Acinetobacter baumannii bacteria—a leading cause of ventilator-associated pneumonia, according to a study published Nov. 15 in the journal Nature Microbiology.

Harvard Medical School researchers have taken another decisive step in their efforts to develop a gene therapy for people with Usher syndrome type 1F, a rare condition that causes deafness and progressive blindness.

Waning vaccine coverage has fueled a 20% spike in measles cases worldwide, with 10.3 million people struck by the preventable illness in 2023, health officials reported Wednesday.

A novel test developed by Duke-NUS researchers enables real-time monitoring of T cells that have been engineered to fight cancer after re-introduction into the body of a cancer patient. This simple and innovative test provides clinicians with the ability to track the function of these cancer-fighting cells over the course of the treatment.

An experimental vaccine has shown promise in protecting against the sexually transmitted disease chlamydia, researchers report.

The overseas French territory of Guadeloupe declared a dengue epidemic on Thursday, with authorities noting the outbreak was being driven by a less common strain of the mosquito-borne disease.

A new paper led by a Concordia researcher examines how social isolation, loneliness and frailty affect one another and the bidirectional relationship they exert as an individual gets older.

A University of Miami study offers new insights into language development in children with hearing loss, suggesting language learning strategies that may help children with cochlear implants—surgically implanted hearing devices—overcome initial language development delays.

Many individuals with sickle cell anemia undergoing controlled ovarian hyperstimulation (COH) with oocyte cryopreservation (OC) have complications, according to a study scheduled for presentation at the annual meeting of the American Society of Hematology, to be held from Dec. 7 to 10 in San Diego.

A new variant of human mpox has claimed the lives of approximately 5% of people with reported infections in the Democratic Republic of the Congo since 2023, many of them children. Since then, it has spread to several other countries. The World Health Organization declared the outbreak a Public Health Emergency of International Concern on August 14. In addition, a different but rarely fatal mpox va

The effects of war on those who fight and witness it firsthand can linger long after peace has been made and the troops have come home. In Canada, it is estimated that 10% of war-zone veterans will develop post-traumatic stress disorder (PTSD) while others will exhibit at least some of its symptoms.

Thousands of kidney disease patients' lives could be saved around the world each year if countries adopted the UK's rules on organ donation, new research has revealed.

The first report from a Royal Commission of Inquiry to review New Zealand's response to the COVID pandemic was due to be released this month.

An international, Phase III clinical trial led by investigators at Mass General Brigham could improve the treatment of a rare disease that can cause debilitating symptoms. The study, published in the New England Journal of Medicine, found that treatment with inebilizumab greatly reduced the symptoms of immunoglobulin G4–related disease (IgG4-RD), compared to placebo.

Measles infections soared by a fifth last year to over 10 million cases globally, revealing alarming gaps in vaccine coverage, a study showed Thursday.

An international team of researchers led by Professor Dr. Lucas Schirmer and Professor Dr. Julio Saez-Rodriguez from the Mannheim and Heidelberg Medical Faculties of Heidelberg University has investigated the composition and communication of cells in so-called subcortical lesions, tissue damage to deep brain structures at different stages of multiple sclerosis (MS).

A deep learning artificial intelligence model developed at Washington State University can identify pathology, or signs of disease, in images of animal and human tissue much faster, and often more accurately, than people.

A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight days to recover for patients who received asunercept, a biotherapeutic FasL inhibitor, compared to 13 days in the control group.

The African Union's health watchdog said Thursday it has endorsed an mpox test from Morocco, hailing it as a "major milestone" to help combat the outbreak on the continent.

Rwanda's health minister on Thursday declared an end to the outbreak of the deadly Marburg virus in the country, with no new cases for nearly two weeks.

Since its discovery in 1998 and winning the Nobel Prize in 2006, ribonucleic acid (RNA) interference has become an invaluable tool for drugmakers to silence disease-causing genes. Nearly three decades later, drug makers have developed six approved small interfering RNA (siRNA) therapeutics in the therapeutic areas of neurology, cardiovascular, endocrine, and metabolism, such as amyloidosis, famili

Viruses are the fastest-evolving biological entity on Earth. This fact explains why we need flu shots every year: Seasonal influenza perennially outwits the immunity we've acquired from previous vaccinations or infections.

During the first 14 months of the Sudan conflict, there have been more violent deaths in Khartoum State alone than the current number of violent deaths recorded for the entire country, a new study suggests.

Many bacterial-linked illnesses, such as inflammatory bowel disease or colorectal cancer, are associated with an overgrowth of gut bacteria thought to be bad actors. But when researchers used a machine learning algorithm to predict the density of microbes—called microbial load, from their gut microbiomes, they found that changes in microbial load, rather than the disease, could be a driver behind

A new clinical practice guideline developed by the American Academy of Sleep Medicine provides updated recommendations for the treatment of restless legs syndrome. The guideline reflects the latest scientific evidence and recommends significant changes in the standard treatment of RLS in adults.

Obesity, alcohol use and other factors are driving up rates of fatty liver disease among American adults, new research warns.

Around 2 to 3 million people live with hepatitis C in the U.S. and 40% of those people (roughly 800,000) were not even aware that they had the infection. Hepatitis C is common and completely treatable.

The U.S. Food and Drug Administration has approved Journey Medical's Emrosi (minocycline hydrochloride) for the treatment of inflammatory rosacea in adults.

A Canadian teen is hospitalized in critical condition with what is believed to be bird flu, a British Columbia health official said Tuesday.

Specific combinations of long term conditions have a major role in the additional pressures the NHS faces every winter, because they are associated with significantly higher risks of hospital admissions and death, finds research published in the open access journal BMJ Medicine.

Researchers from Johns Hopkins Medicine and Yale University have collaborated on the development and application of a diagnostic model to detect acute interstitial nephritis (AIN) in patients, which could have a lasting impact on getting patients diagnosed earlier.

While great strides have been made to ensure children have access to proper asthma care in their home and community, linking those environments to the care that children receive while in school has been a challenge. In a new study, researchers from Children's Hospital of Philadelphia (CHOP) demonstrate that community health workers can play a critical role in integrating all environments where chi

Researchers at Kennedy Krieger Institute's International Center for Spinal Cord Injury (ICSCI) have made a remarkable advancement in treating children with acute flaccid myelitis (AFM), a rare but severe neurological condition that causes sudden paralysis.

Many people may think of dyslexia as a reading difficulty, or the occasional embarrassing mix-up of letters. For years, I thought that too. But as a dyslexic academic who has spent much of my life wrangling with academic norms, I've realized that dyslexia isn't just a barrier. It's also a unique and undervalued cognitive strength.

A strain of the bacterium Klebsiella pneumoniae isolated from an 86-year-old woman with a urinary infection admitted to hospital in Brazil's Northeast region in 2022 proved resistant to all available antibiotics. The patient died 24 hours after being hospitalized.

The Finnish epilepsy care pathway has been published in Epilepsia Open. This Finnish model for epilepsy care provides a streamlined, multidisciplinary approach to the diagnosis and treatment of epilepsy, and combines modern digital tools, data sharing and peer support. The Finnish epilepsy care pathway can serve to model how integrated health care systems can effectively manage complex conditions.

The U.S. syphilis epidemic slowed dramatically last year, gonorrhea cases fell and chlamydia cases remained below prepandemic levels, according to federal data released Tuesday.

Over the last 20 years, vast advancements in the field of biotechnology have led to the development of a research approach called multi-omics, which looks at multiple layers of biological information—like gene expression, proteins, and metabolites—all at once to get a complete picture of how the body functions.

A genomic test developed at UC San Francisco to rapidly detect almost any kind of pathogen—virus, bacteria, fungus or parasite—has proved successful after a decade of use.

Scientists at deCODE genetics have published a study in Nature Communications that sheds light on how body mass index (BMI) influences the risk of various diseases that are comorbid with obesity. The study, which used genetic data from Iceland and the UK Biobank, looked at whether disease risks associated with BMI-related sequence variants are explained completely or partially by their effect on B

All aspects of religiosity, spirituality, and meaning-making (R/S/M) relate to suicidality in people with a psychiatric diagnosis or a recent suicide attempt, according to a systematic review and meta-analysis published in Harvard Review of Psychiatry.

Nearly five years into the pandemic, COVID is feeling less central to our daily lives.

The World Health Organization said mpox cases in the region of Congo where a new and more infectious variant was first detected appear to be "plateauing," even as the virus continues to increase in other regions of the country, as well as in Burundi and Uganda.

Natalie Holt sees reminders nearly everywhere of the serious toll a years-long syphilis outbreak has taken in South Dakota. Scrambling to tamp down the spread of the devastating disease, public health officials are blasting messages to South Dakotans on billboards and television, urging people to get tested.

More than 1 in 5 Americans likely suffer from long COVID, a new AI-assisted review has found.

A teenager in British Columbia has become the first person in Canada to test positive for bird flu, authorities said Saturday.

The biomarker human neutrophil lipocalin HNL was previously shown to be a useful indicator of bacterial infections. Now, the dimeric form of HNL may also be used to effectively monitor the success of antibiotic treatment in sepsis.

COVID-19 is associated with long-term risk for autoimmune and autoinflammatory connective tissue disorders, according to a study published online Nov. 6 in JAMA Dermatology.

A new World Health Organization (WHO) study published in eBioMedicine names 17 pathogens that regularly cause diseases in communities as top priorities for new vaccine development. The WHO study is the first global effort to systematically prioritize endemic pathogens based on criteria that included regional disease burden, antimicrobial resistance risk and socioeconomic impact.

During the COVID-19 pandemic, above all before vaccines were available, an alarm was sounded regarding a possible correlation between severe cases of COVID-19 in pregnant women and preeclampsia, a condition characterized by high blood pressure (hypertension) in the expectant mother and high levels of protein in her urine (proteinuria). It can entail dangerous complications for mother and baby.

Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity.

Investigators at Mass General Brigham have developed an AI-based tool to sift through electronic health records to help clinicians identify cases of long COVID, an often mysterious condition that can encompass a litany of enduring symptoms, including fatigue, chronic cough, and brain fog after infection from SARS-CoV-2.

Researchers at Kumamoto University have made a significant breakthrough in the fight against COVID-19 with the development of "Intelli-OVI," a cutting-edge diagnostic tool capable of rapidly identifying emerging variants of the SARS-CoV-2 virus.

This year could shape up to be the worst year for whooping cough Washington has seen in over a decade.

Not everyone responds equally well to treatments for inflammatory bowel disease (IBD). What will work for individual patients involves trial and error during the treatment process. Now, a team of researchers led by Charité—Universitätsmedizin, in collaboration with colleagues in Berlin and Bonn, has succeeded in identifying a biomarker that indicates whether or not treatment with a certain medicat

Health care providers treating people with COPD also need to focus on the person's socioeconomic factors, along with considering their additional health conditions or comorbidities, according to a new article. The article is published in the September 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.

In an exploration of psychedelic medicine's potential for treating one of psychiatry's most challenging conditions, researchers at University of California, San Diego (UCSD) have provided an analysis and further details of a trial published in Nature Medicine that showed how psilocybin therapy affects individuals with anorexia nervosa.

A nationwide study from Japan spanning a 14-year study period has revealed an increasing trend of overweight and obesity in patients with incident end-stage kidney disease (ESKD).

After "Friends" star Matthew Perry was found dead in his home jacuzzi just over a year ago, an autopsy later pinpointed the main cause of death as an acute ketamine overdose.

The spread of mpox has slowed down slightly across Africa but the epidemic is not over, the African Union's health watchdog said Thursday.

About 7% of dairy workers exposed to the avian flu that is spreading through U.S. herds have become infected themselves, federal experts estimate.

Xiaoguang Dong, assistant professor of mechanical engineering at Vanderbilt University, is leading a team of researchers that has developed a system of artificial cilia capable of monitoring mucus conditions in human airways to better detect infection, airway obstruction, or the severity of diseases like cystic fibrosis (CF), chronic obstructive pulmonary diseases (COPD) and lung cancer.

Seasonal influenza epidemics impose substantial burdens on health care systems and cause >5 million hospitalizations of adults each year. The current approach to influenza vaccine development requires comprehensive surveillance of circulating strains, which are constantly moving from continent to continent.

Research analyzing European survey data from 113,884 men who have sex with men (MSM) and published in Eurosurveillance indicates that while most MSM have a basic understanding of viral hepatitis, only 44% report having been vaccinated against both hepatitis A and B. The data highlight notable immunization gaps despite available vaccination and recommendations. Strong public health support and crea

Bangladesh is struggling to tamp down a surge in dengue cases as climate change turns the disease into a year-round crisis, leaving some pediatric wards packed with children squeezed two to a bed.

British health officials say they have identified four cases of the new, more infectious version of mpox that first emerged in Congo, marking the first time the variant has caused a cluster of illness outside of Africa. Scientists said the risk to the public remains low.

A wide variety of COVID-19 symptoms exist, ranging from mild to severe, and while current strains of the virus generally cause milder symptoms, those with co-morbidities are still at an exponentially greater risk of severe disease.

Serum zinc is often deficient in patients with liver cirrhosis and hepatic encephalopathy (HE), according to a study published online in the September issue of the Journal of Family Medicine and Primary Care.

Waterborne diseases affect more than 7 million people in the U.S. every year, according to the Centers for Disease Control and Prevention, and cost our health care system over $3 billion. But they don't impact all people equally.

An estimated 1.2 million children develop tuberculosis disease (TB) and 200,000 kids die from TB worldwide each year, but the risk of developing TB infection and disease throughout childhood remains under-studied.

Health Canada has published a report from a group of experts tasked with reviewing the federal government's approach to scientific advice and coordination of pandemic research.

University of California, San Francisco and the University of Alabama at Birmingham researchers have identified a link between social isolation and increased mortality among adults with chronic obstructive pulmonary disease (COPD), according to a study published in JAMA Internal Medicine.

Two new cases of the mpox variant clade 1b detected in the UK are the first locally transmitted cases in Europe and the first outside Africa, the World Health Organization said Tuesday.

There is a bidirectional association for rheumatoid arthritis (RA) and interstitial lung disease (ILD), according to a study published online Oct. 12 in the Journal of Clinical Medicine.

In a multisociety clinical practice guidance document, published online Oct. 29 in Surgery for Obesity and Related Diseases, recommendations are presented for the safe use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in the perioperative period.

Seriously ill patients and family members face intense emotional suffering. Even a single word may scare patients and families, make them feel disempowered, and possibly negate the effectiveness of shared decision making.

In many countries around the world, wild animals are sometimes killed for food, including monkeys, rats and squirrels.

A study has found that the voluntary, community, faith and social enterprise (VCFSE) sector played a "crucial" role supporting Greater Manchester communities during the COVID-19 pandemic and vaccine rollout—but that their contribution has been undervalued and under-recognized by the wider health system.

H5N1 influenza has now been detected in pigs. This was something virologists had been worrying about ever since this highly pathogenic strain of bird flu started its rapid global spread in 2020. But why were we worrying specifically about pigs? And does this case—detected on a farm in Oregon on October 29—change anything?

The United States Department of Agriculture last week reported that a pig on a backyard farm in Oregon was infected with bird flu.

Erasmus University Medical Center researchers in Rotterdam have tracked vitamin D supplementation improvements in bone mineral density among patients with erythropoietic protoporphyria.

A study of 7 million medical records found that in Australia, patients with long COVID are more likely to be women than men, or people aged 40–59 and those living in a high socioeconomic area. They usually have pre-existing health problems.

While the emergence of colorful butterflies is a welcome sign of summer, the constant buzzing of mosquitoes is an annoying part of the season.

Individuals with a history of upper respiratory infections (URI) have an increased risk for developing Meniere disease (MD), according to a study published online Oct. 10 in Microorganisms.

Countries reconvened on Monday in a bid to finalize a landmark global agreement on handling future pandemics, with the specter of mpox, Marburg and H5N1 adding fresh urgency to seal a deal.

During certain seasons of the year, you may notice changes in your energy level, sleep and interest in activities.

Some health officials say mpox cases in Congo appear to be "stabilizing"—a possible sign that the main epidemic for which the World Health Organization made a global emergency declaration in August might be on the decline.

A concerning increase in global rates of severe invasive infections becoming resistant to key antibiotics has a team of infectious disease researchers at the Houston Methodist Research Institute studying a recently emerged strain of bacteria called Streptococcus dysgalactiae subspecies equisimilis (SDSE). SDSE infects humans via the skin, throat, gastrointestinal tract and female genital tract to

A study led by researchers at Albert Einstein College of Medicine involving more than 200,000 adults found that the COVID-19 pandemic caused a 29% increase in risk for developing dyslipidemia, a condition involving abnormal lipid (fat) levels in the blood.

Chronic kidney disease (CKD) cases and deaths in women surged worldwide between 1990 and 2021, according to a study presented at Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to 27 in San Diego.

Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care—critical to preventing life-threatening sepsis.

When a mysterious and deadly illness began to sicken members of the Navajo community in the Four Corners region of the Southwestern U.S. in 1993, U.S. Centers for Disease Control and Prevention (CDC) investigators were stumped.

Rwanda has been stepping up measures to combat Rift Valley Fever (RVF) following the country's second outbreak in two years, amid concerns it could spread to humans.

Do you have a runny nose and nagging cough that has persisted for weeks but you've still managed to drag yourself to work and school?

Nepal is fighting a surge in dengue cases, a potentially deadly disease once unheard of in the country's high-altitude Himalayan regions, as climate change and urbanization nurture fever-bringing mosquitoes in new zones.

Research published in the journal Glia has identified crucial links between dietary choices and the progression of multiple sclerosis (MS).

Doctors in New York City are describing the first known U.S. cases of sexually transmitted ringworm, which can cause a nasty rash that can take months to bring under control.

Most small kidney stones can pass on their own. However, kidney stones that are too large to pass on their own or cause bleeding, kidney damage or ongoing urinary tract infections may require surgical treatment. Dr. Aaron Potretzke, a Mayo Clinic urologist in Rochester, Minnesota, explains some of the different surgical options for removing kidney stones.

The American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS), along with a growing number of endorsing medical societies and organizations, have called on battery manufacturers to act immediately to bring a safe button or coin cell battery to the consumer marketplace to mitigate the life-threatening results and risks when these batteries are lodged in the body.

A study by Charles Darwin University (CDU) has leveraged the unique context of mandatory mask-wearing during the COVID-19 pandemic to explore the relationship between stuttering, anxiety-related safety behaviors, and the challenge of maintaining open communication.

Delayed Meniere disease (DMD) is associated with a higher prevalence of bilateral Meniere disease (MD) compared with classic MD (CMD), according to a study published online Oct. 15 in the European Archives of Oto-Rhino-Laryngology.

Injected micronized amnion/chorion bilayer (AC) product significantly reduces time to symptom relief in patients with refractory interstitial cystitis/bladder pain syndrome (IC/BPS), according to a study published online Oct. 23 in International Urology & Nephrology.

The hepatitis E virus affects the liver. But infected liver cells secrete a viral protein that reacts with antibodies in the blood and may form complexes that can damage the filter structure of the kidneys, as researchers from the University of Zurich and the University Hospital Zurich have proven for the first time.

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health sheds light on how the blood-borne parasite that causes African sleeping sickness in humans and related diseases in cattle and other animals establishes long-term infections in hosts.

Northeastern University professors of pharmacy say the updated COVID-19 vaccines available for fall and winter of 2024 are a good match for the dominant strain of SARS-CoV-2 currently in circulation.

University of Queensland-led research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

Influenza-associated hospitalization rates vary across seasons, and only returned to recent pre-COVID-19 pandemic levels in the 2022–2023 influenza season, according to research published in the Oct. 31 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Whooping cough is on the rise in the United States, with cases surging across the nation.

A study by the University of Pennsylvania and researchers from 26 U.S. children's hospitals has linked elevated body mass index (BMI) to a significantly higher risk of developing post-acute sequelae of SARS-CoV-2 infection (PASC) among children and young adults.

A pig at an Oregon farm was found to have bird flu, the U.S. Department of Agriculture announced Wednesday. It's the first time the virus has been detected in U.S. swine and raises concerns about bird flu's potential to become a human threat.

A new study published in the American Journal of Infection Control describes the outcome of a shift in hospital screening protocols for Candida auris, a dangerous and often drug-resistant fungal pathogen that spreads easily in hospital environments.

Herpes simplex virus type 1 (HSV-1), the cause of the common cold sore, can spread into the central nervous system and preferences for certain parts of the brain. Study results published today in the Journal of Virology are among the first to recognize how this common virus infiltrates the brain, leading to a better understanding of how HSV-1 may trigger neurological diseases.

A new study—published in Nursing Research—has found that the COVID-19 pandemic significantly impacted patient safety indicators in U.S. hospitals. The study, from Penn Nursing's Center for Health Outcomes and Policy Research (CHOPR), examined data from the National Database of Nursing Quality Indicators to assess trends in nursing-sensitive quality indicators from 2019 to 2022. The prevention of t

Increasing ketones in the blood through a keto diet or supplements may help put irregular menstrual cycles back on schedule or even restart a period that appears to have stalled for good, new research suggests.

Atrasentan is associated with a significant and clinically meaningful reduction in proteinuria compared with placebo in patients with immunoglobulin A (IgA) nephropathy, according to a study published online Oct. 25 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to 27 in San Diego.

An infection with the latest mpox variant, clade 1b, has been detected in the United Kingdom for the first time, the UK Health Security Agency (UKHSA) announced on Wednesday.

"People have forgotten what life is all about," Robert De Niro's character says in the film "Awakenings" after being revived from the shut-down state he had been in for 30 years. "They've forgotten what it is to be alive."

More than 8 million people were diagnosed with tuberculosis last year, the World Health Organization said Tuesday, the highest number recorded since the U.N. health agency began keeping track.

The high school party days never really ended for a surprising number of middle-aged adults. A University of Michigan study reveals that adults aged 35 to 60 are drinking at unprecedented rates, with a striking link between high school binge drinking and risky midlife alcohol consumption.

With growing concern about the ubiquity of toxic chemicals in consumer products, many states have passed laws aimed at protecting people from harmful substances in everyday items like cosmetics, cleaning supplies, plastics, and food packaging. California's Proposition 65, for instance, is considered one of the most extensive toxics laws in the country.

Almost half of the world's population is at risk of malaria infection, with children and pregnant women at the highest risk of getting sick and dying from the disease. Current methods to detect this potentially deadly infection rely on obtaining an invasive blood sample, and each test has significant limitations that restrict their utility.

Researchers from the Charlie Dunlop School of Biological Sciences, in collaboration with The Oxford Research Centre in the Humanities, reveal a powerful link between olfactory loss and inflammation in a staggering 139 medical conditions. This research—led by professor emeritus Michael Leon, and researchers Cynthia Woo and Emily Troscianko—emphasizes a little-known but potentially life-altering con

Researchers have discovered that a protein complex that helps fight cancer cells also slows the growth of tuberculosis—a finding that could mean better treatments for both diseases. The protein complex, which slows down the growth of tuberculosis (Mtb) bacteria in infected immune cells and enables them to survive infection, represents a newly discovered way human cells defend against bacterial inf

Researchers have demonstrated a new technique for COVID surveillance that can signal the rise of new variants before they are widespread. The study, led by the American Museum of Natural History and Columbia University and published in the journal Genome Research, presents a way to track diversity across millions of genomes sequenced during the height of the COVID-19 pandemic using new surveillanc

An antibody called bFKB1 improves liver disease and atherosclerosis in a mouse model of metabolic dysfunction-associated steatohepatitis (MASH), which is associated with obesity. The antibody also decreased body weight and improved inflammation and insulin sensitivity. Learning how the antibody exerts these effects could someday lead to development of a new drug to fight MASH, according to researc

Two patients being treated for pneumonia, an infection that causes difficulty breathing due to fluid-filled sacs in the lungs, can look vastly different and have opposing outcomes. Yet doctors struggle to accurately predict patients' prognoses and determine the most effective treatments.

Exposure to lead can adversely impact people's health in several ways. A Purdue University researcher in the College of Health and Human Sciences has developed noninvasive methods that detect levels of lead exposure in bone and blood faster, easier and with greater sensitivity at the point of care than traditional methods.

A new study from Murdoch Children's Research Institute (MCRI) has found clinicians can benefit from plain language guides and graphics about genetic testing.

Health officials are investigating the case of an Iowa resident who died of Lassa fever after traveling recently to West Africa. The Ebola-like virus is rarely seen in the United States, according to the U.S. Centers for Disease Control and Prevention.

To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental Biology within Penn Medicine, the kidney is a work of art. "I find the development of the kidney to be a really beautiful process," says Hughes.

As poultry farms and dairies across California battle bird flu outbreaks, some are wondering if their food is safe to eat.

A genetic signature in newborns can predict neonatal sepsis before symptoms even start to show, according to a new study.

Malaria, spread by Anopheles mosquitoes, is one of the deadliest diseases in the world. In Kenya, malaria remains a major health challenge, particularly for children under the age of five years. With over 5 million cases reported annually, climate change is expected to exacerbate the situation by enabling the disease to spread to new areas.

New research is exploring low-cost, non-invasive ways to diagnose Barrett's esophagus, a condition associated with deadly esophageal cancer, to find effective strategies to identify patients with this condition.

Researchers at the University of Alberta have pinpointed two proteins that could serve as markers for identifying patients with long COVID—a discovery that may lead to treatments that will bring better quality of life for the millions of people suffering from the debilitating condition.

Researchers have identified the skin cells responsible for orchestrating cases of two of the most life-threatening drug reactions. Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) cause the skin and mucous membranes to blister and detach, and carry an average mortality rate of 20%.

Asbestos may have been banned from use in the UK since 1999, but the hazardous material continues to pose a serious danger to the population.

Long-term treatment of adolescents with moderate-to-severe atopic dermatitis (AD) with upadacitinib is safe and effective through 76 weeks, according to a study published online Oct. 23 in JAMA Dermatology.

Babies and young children with Down syndrome can often be late to reach early motor milestones. But Jerry Wu, a professor of kinesiology and health and department chair at Georgia State University, is working on research that could change that.

A severe outbreak of E. coli linked to McDonald's Quarter Pounder burgers has expanded to 75 reported cases, mainly in the western United States, authorities said Friday.

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface. A recent Phase II trial revealed that felzartamab, an investigational anti-CD38 monoclonal antibody, helps to reduce proteinuria and maintain patients' kidney function.

Prior efforts to identify novel kidney biomarkers as risk factors for chronic kidney disease (CKD) progression have typically evaluated proteins individually, which limits their prognostic power.

A recent analysis reveals that the number of chronic kidney disease (CKD) cases in women around the globe nearly tripled in the past three decades. Also, type 2 diabetes and hypertension were the leading causes of CKD-related deaths in women. The research was presented at ASN Kidney Week 2024 October 23–27.

Viral hemorrhagic fevers (VHF) such as Marburg virus disease have been in the news recently, with more than 60 cases of Marburg confirmed in Rwanda.

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare autoimmune disease of the central nervous system. According to estimates, 1 to 3 in 100,000 people are affected. They may suffer from visual disturbances, paralysis, incontinence and pain. But do they also have cognitive impairments?

Patients hospitalized with COVID-19 often report a wide range of symptoms months after their initial illness. But a new study from NDORMS shows that post-acute infection syndrome (PAIS) is not unique to COVID-19 and can also occur after other respiratory infections.

The COVID-19 pandemic and subsequent vaccination rollout enabled a "perfect storm" for deepening health inequalities in Greater Manchester, the results of a study have shown.

A new Burnet Institute study finds that introducing a hepatitis C outreach and treatment program in Australian community pharmacies, particularly those offering opioid agonist therapy, could significantly increase testing, diagnosis, and cure of those living with the blood-borne virus. The study is published in the Journal of Viral Hepatitis.

A total of 2,729 new suspected cases of the disease mpox have been reported in Africa over the period of one week, according to the Africa Centers for Disease Control and Prevention.

Investigators recently uncovered key insights into newly defined rejection entities in kidney transplantation that may offer improved patient risk categorization post-transplant. The research will be presented at ASN Kidney Week 2024, from October 23–27.

Next time you're on a cruise, be wary of your (or your neighbor's) private balcony hot tub, researchers warn. These luxe cabin features were pinpointed as a source of outbreaks of the respiratory illness Legionnaires' disease that broke out on two ships.

Boarding admitted patients in the emergency department for acute stroke is financially costly, according to a study published in Annals of Emergency Medicine.

For the first time, scientists have found that individuals in Nigeria are experiencing neurological manifestations of long COVID—called neuro-long COVID—such as brain fog, mild cognitive impairment, fatigue, sleep problems, headache, sensations of pins and needles, and muscle pain. Their findings are published in the Journal of NeuroVirology.

Health officials said Thursday that there's no evidence bird flu is spreading between people after investigating a mysterious infection in Missouri.

Researchers from Johns Hopkins Children's Center say they have identified a gene pathway involving the mineral zinc in mice that may someday point the way to using zinc-based supplements to directly help people with a rare disorder called short bowel syndrome (SBS).

Federal and public health officials in multiple states are investigating an outbreak of E. coli infections linked to McDonald's Quarter Pounder, according to the Centers for Disease Control and Prevention. Officials are determining which ingredient may be harboring the bacteria that caused the outbreak.

New research published this month shows the key role quality improvement programs play in ensuring hospitals can adequately fight one of the biggest public health threats facing our country: stroke.

A team of engineers at the University of Houston has published a study in the journal Scientific Reports on how international air travel has influenced the spread of COVID-19 around the world. By using a newly developed AI tool, the team identified hotspots of infection linked to air traffic, pinpointing key areas that significantly contribute to disease transmission.

During the COVID pandemic, many of us received multiple mRNA vaccines. New work by researchers at the VIB-UGent Center for Inflammation Research, Ghent University, and University Hospital Ghent, among others, has found that such repeated vaccinations lead to the presence of mucosal antibodies, for example, inside the nose. Their work appears in Science Translational Medicine.

Early detection is critical when it comes to curing diseases like cancer, but not everyone has easy access to screening tools. For problems in the genitourinary (GU) tract (which includes the kidneys, prostate, and bladder), health providers usually use a combination of screening tools, including blood tests, imaging, and physical examinations. Scientists are now working on an even simpler tool fo

A recent study by Dr. Jordan Verplank, Assistant Professor in the Department of Anatomy, Physiology, and Genetics at the Uniformed Services University of the Health Sciences (USU), and a team of scientists from USU, State University of Buffalo (New York), and Cyclerion Therapeutics, has identified a promising approach for treating hereditary peripheral neuropathies, specifically Charcot Marie Toot

Swiss pharmaceutical giant Roche said Wednesday that it was increasing its capacity to produce diagnostic tests to detect mpox, amid a flare-up of the potentially deadly virus.

Artificial intelligence experts and health care professionals in Portsmouth have come together to help prevent a common and painful complication in advanced kidney failure treatment.