All articles tagged: Diseases, Conditions, Syndromes

Imagine being a paramedic treating a trauma patient who's bleeding severely. You know your patient's life is in danger, but there's not much you can do because the patient needs an infusion of blood containing platelets. Platelets encourage clotting, help stop bleeding, and are critical in emergencies like this. Yet on board your ambulance, none are on hand.

At the beginning of the COVID-19 pandemic, a group of Brazilian researchers showed why SARS-CoV-2 infection tends to be more severe in diabetic patients. Now, the same team based at the Institute of Biology of the State University of Campinas (IB-UNICAMP) has discovered one of the reasons why obese people who do not have diabetes or even insulin resistance also have an increased risk of developing

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

Distinct phenotypic and urine biological characteristics are seen for patients with interstitial cystitis/bladder pain syndrome (IC/BPS) with a history of ulcerative Hunner lesions (UIC) and those with no lesions (NHIC), according to a study recently published in the American Journal of Clinical and Experimental Urology.

A new study in mice hints at the promise of an eventual alternative treatment option for the "wet" version of age-related macular degeneration (AMD).

Distension of the membranous labyrinth is seen in histologic specimens from deceased patients with symptoms consistent with Meniere disease and in magnetic resonance imaging (MRI) from patients exhibiting classic Meniere disease symptoms, according to a study published online June 13 in the Ear, Nose & Throat Journal.

People who have received solid organ transplants and take immunosuppressant medications to prevent rejection are among those most susceptible to the damaging effects of COVID-19, including breakthrough infections, severe illness, hospitalization and death.

Obesity in children is associated with double the risk of hospitalization for dengue virus infection, according to a study published in PLOS Neglected Tropical Diseases.

A study published in Nature Communications presents the promising results of RecombinHunt, a new data-driven method developed by the Department of Electronics, Information and Bioengineering of the Politecnico di Milano and the University of Milan, which can identify, with high accuracy and computational efficiency, recombinant SARS-CoV-2 genomes with one or two breakpoints.

A research team including Professor Yoontae Lee and Jiho Park, a Ph.D. candidate, from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH) has discovered that a particular protein promotes the development of systemic lupus erythematosus (SLE).

Taxing certain antibiotics could help efforts to tackle the escalating threat of antibiotic resistance in humans, according to a new study by the University of East Anglia's Centre for Competition Policy, Loughborough University and E.CA Economics.

Genital herpes infections and their related complications lead to billions of dollars in health care expenditures and productivity losses globally, according to the first ever global estimates of the economic costs of these conditions.

High exposure to volatile organic compounds (VOCs) is independently and positively associated with overactive bladder (OAB) risk, according to a study published in Frontiers in Public Health.

Measuring the level of homocysteine—an amino acid—in the blood can help predict a person's risk of developing obstructive sleep apnea, a disorder characterized by recurrent interruptions in breathing due to relaxation of the throat muscles during sleep. This simple blood test can also help clinicians gauge whether a patient with the mild or moderate form of the disorder is likely to develop the se

In a clinical practice guideline issued by the International Society on Thrombosis and Haemostasis and published online June 13 in the Journal of Thrombosis and Haemostasis, recommendations are presented for the treatment of congenital hemophilia.

For patients with severe obesity undergoing knee or hip replacement, commonly obtained laboratory values—including markers of anemia and inflammation—are independent predictors of the risk of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery.

The COVID-19 pandemic had an unprecedented effect on college students' mental health. Symptoms like anxiety and major depression in young adults ages 18-25 increased significantly compared to before the pandemic.

As bird flu continues to spread among U.S. dairy cows, reassuring new government research finds the pasteurization process widely used in the industry effectively kills all bird flu virus in milk.

Countries in Asia Pacific are unlikely to meet their commitment to eliminate hepatitis by 2030 unless they declare a public health emergency, as they did with COVID-19, a disease specialist suggested.

Animal influenza viruses such as swine and bird flu pose a risk to humans, in particular those in the farming and veterinarian communities. Most recently, flu viruses have been circulating in cow populations, contaminating machinery and milk, leading to cases of infection among farmworkers.

Signs of H5N1 bird flu virus have been detected at three wastewater sites in California's Bay Area, according to sampling data.

An experimental monoclonal antibody has been engineered to target the deadly Nipah virus, an emerging zoonotic pathogen with a human mortality rate ranging as high as a staggering 90%.

Osteoarthritis (OA) represents the most prevalent form of chronic degenerative joint disease worldwide. The dynamic interplay between cartilage and subchondral bone is essential for preserving joint structural and functional integrity. In addition to cartilage degeneration, pathological alterations within the subchondral bone significantly contribute to OA progression. Therefore, there is an urgen

Tampere University researchers developed a method to map mechanistic connections between diseases, revealing deeper associations beyond traditional classifications based on affected organs and symptoms. This multi-dimensional approach presents a paradigm shift in disease classification and drug discovery, potentially leading to more personalized and effective medical treatments.

Florida is one of 39 states that is seeing an increase or likely seeing an increase in COVID infections, according to the U.S. Centers for Disease Control and Prevention.

Here's a look at the state of COVID-19 in the U.S. as the Centers for Disease Control and Prevention establishes its latest advice on vaccinations.

With fresh COVID-19 cases bubbling up in some parts of the country, health officials are setting course for a fall vaccination campaign.

A new study brings fresh revelations about the connection between early-life exposure to air pollution and lung health later in life. A research team led by the Keck School of Medicine of USC has shown that exposure to air pollution during childhood is directly associated with bronchitis symptoms as an adult.

Drug development is typically slow: the pipeline from basic research discoveries that provide the basis for a new drug to clinical trials to production of a widely available medicine can take decades. But decades can feel impossibly far off to someone who currently has a fatal disease.

What happens when the measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.

Bird flu, or H5N1 virus, in unpasteurized milk is stable on metal and rubber components of commercial milking equipment for at least one hour, increasing its potential to infect people and other animals, report researchers from the University of Pittsburgh School of Medicine and Emory University in Emerging Infectious Diseases.

Effective control of bovine schistosomiasis will be required to meet disease elimination targets in humans, new research shows.

A more accurate way to scan for tuberculosis (TB) has been developed by UK and US researchers, using positron emission tomography (PET).

While the liver is one of the body's most resilient organs, it is still vulnerable to the ravages of stress and aging, leading to disease, severe scarring and failure. A Duke Health research team now might have found a way to turn back time and restore the liver.

Moderate levels of physical activity and fitness may be linked to a reduced risk of amyotrophic lateral sclerosis (ALS) later in life, according to a new study published in Neurology. However, the study only found an association between physical activity and risk of ALS in male participants, not female participants.

A new editorial paper titled "Global consensus for sarcopenia" has been published in Aging.

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease caused by a mutation in the gene IFITM5.

Service dogs can alleviate some symptoms of post-traumatic stress disorder for veterans, according to a study our team published in June 2024 in the medical journal JAMA Network Open.

The family of actor Bruce Willis, best known for the Die Hard movie franchise, announced in 2022 that he was retiring from acting because he had a brain disorder that affected his ability to speak. Their statement called it aphasia, which is an acquired loss of language skills.

The emergence of long COVID as a mysterious new illness has refocused attention on the incapacitating nature of persistent fatigue.

Sexually transmitted infections (STIs) are on the rise in the U.S., including an 80% increase in syphilis over a five-year period, according to the Centers for Disease Control and Prevention. A new national survey by The Ohio State University Wexner Medical Center finds many Americans have misconceptions on how STIs are spread and who should be treated.

In July 2023, a New Castle County resident was getting ready for bed when they pulled back their comforter and saw a large black and orange insect sitting on their pillow.

A new deadlier strain of mpox that transmits more easily between people is killing children and causing miscarriages in the Democratic Republic of Congo and may have already spread to neighboring countries, researchers have warned.

EPFL scientists have discovered that in indoor spaces, droplets containing the flu virus will remain infectious for longer when they also contain certain types of bacteria found in our respiratory tract. This finding provides important insight into how respiratory infections are transmitted and can enhance estimates of exposure risk.

Vanderbilt University Medical Center (VUMC) researchers are touting data from a multicenter, international Phase II clinical trial showing a new, curative treatment for sickle cell disease (SCD).

A new study that looked for relationships between early social media use and depression across adolescence and into young adulthood found that certain factors may make social media more risky or protective regarding depression. The findings, which are published in the Journal of Adolescence, suggest that social media use does not impact all adolescents in the same way, and an individualized approa

Surgical drainage of large macular cysts in a patient with Coats disease resulted in an immediate resolution of edema and a gradual resolution of lipid exudates over one year. However, visual recovery was limited due to the chronic nature of the condition. Earlier surgical intervention, in some cases, may allow for visual rehabilitation.

U.S. health officials on Tuesday warned doctors to be alert for dengue cases as the tropical disease breaks international records.

Wayne State University postdoctoral research fellows Patrick Monaghan, Ph.D., and Michael VanNostrand, Ph.D., along with Nora E. Fritz, Ph.D., PT, DPT, NCS, director of the Neuroimaging and Neurorehabilitation Lab and associate professor of physical therapy in the Department of Health Care Sciences in WSU's Eugene Applebaum College of Pharmacy and Health Sciences, recently published a study on mob

Dairy isn't the only food that's good for bone health. Prunes may also protect bone structure and strength in postmenopausal women, according to a new study led by Penn State researchers. The findings, published in Osteoporosis International, suggest that daily prune consumption slows the progression of age-related bone loss and reduces the risk of fracture.

Our lungs are the interface between blood and air. Their role in oxygenating our bloodstream is their primary function, and they bear the brunt of a lot more than just pressures of oxygen and carbon dioxide. Borne upon the air are numerous chemicals, pollutants and particles that can generate many patterns of lung disease.

As one of the leading causes of death in the U.S., kidney disease is a serious public health problem. The disease is particularly severe among Black Americans, who are three times more likely than white Americans to develop kidney failure.

We are living through a mass-disabling event: Over 200 million people worldwide have long COVID. In Canada, one in nine people have experienced long COVID symptoms, and this is likely an underestimate.

In Greek mythology, a water nymph's curse forces a man to stay awake or suffocate. For a rare segment of the population today, the curse is all too real. Now, a team led by University of Connecticut researchers describes in Nature Communications how the curse works on molecules in the brain.

Peek in medicine cabinets across the U.S. and you'll find stacks of leftover COVID tests.

A world-first research discovery from the Storr Liver Center at The Westmead Institute for Medical Research (WIMR) has identified why lean people with metabolic dysfunction-associated fatty liver disease (MAFLD) have higher mortality than their non-lean counterparts.

The U.S. Food and Drug Administration has expanded the approval of Sarepta Therapeutics' Elevidys (delandistrogene moxeparvovec-rokl), a gene therapy for the treatment of Duchenne muscular dystrophy (DMD) in individuals ≥4 years with DMD with a confirmed mutation in the DMD gene.

It's been nearly three months since the U.S. government announced an outbreak of the bird flu virus on dairy farms. The World Health Organization considers the virus a public health concern because of its potential to cause a pandemic, yet the U.S. has tested only about 45 people across the country.

A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics, thanks to a new study led by the University of Surrey. The study is published in the International Journal of Antimicrobial Agents.

A new study led by University of Cincinnati researchers sheds new light on the role of a signaling pathway in the brain to maintain health and prevent inflammation and cognitive deficits.

Giving very premature babies high concentrations of oxygen soon after birth may reduce the risk of death by 50% compared to lower levels of oxygen, says new research led by University of Sydney researchers.

The number of imported cases of dengue in the Greater Paris region increased significantly in the first few months of 2024. In the run-up to the Olympic Games, with huge numbers of international visitors set to come to Paris, especially from endemic dengue countries, scientists say we need to be vigilant.

The most common type of malaria in Brazil is caused by the parasite Plasmodium vivax. Although vivax malaria is milder than the variant caused by P. falciparum, the ability of P. vivax to produce dormant forms in the host's liver that can be reactivated months after the end of treatment makes it very hard to control. According to the scientific literature, such recurrence may account for some 90%

The U.S. Food and Drug Administration has approved Merck's Capvaxive pneumococcal 21-valent conjugate vaccine for the prevention of invasive pneumococcal disease and pneumococcal pneumonia in adults.

Yunusa Bawa spends a lot of time talking about the vaccine for the human papillomavirus that is responsible for nearly all cases of cervical cancer. But on most days, only two or three people allow their daughters to be vaccinated in the rural part of Nigeria where he works.

Between July and October 2023, highly pathogenic avian influenza (HPAI) A(H5N1) was detected in animals on 27 fur farms in Finland. The outbreak, traced to wild birds, revealed significant virus adaptation to mammals. The virus caused severe inflammation in animals' lungs, brains, and livers. Further genetic analyses identified three viral clusters, with mutations facilitating mammalian adaptation

A team of researchers led by Dr. Dao Wen Wang at Huazhong University of Science and Technology has conducted a comprehensive retrospective study analyzing the effects of different diabetes medications on COVID-19 outcomes. This study, involving data from 4,922 patients with COVID-19 and T2DM across 138 hospitals in Hubei Province, China, sheds light on the potential benefits of metformin and alpha

As the deadly disease that came to be known as COVID-19 started spreading in late 2019, scientists rushed to answer a critical question: Who is most at risk?

The Centers for Disease Control and Prevention says wastewater detection of COVID-19 is high or very high in eight states, but whether that means a summer surge in cases remains to be seen.

As a neurodegenerative disease characterized by childhood onset dementia, Sanfilippo syndrome causes immense suffering in many ways, including pain, loss of speech, extreme agitation, and distress, gastrointestinal symptoms, and profound sleep disturbance. With no approved treatment, clinical specialists have had few options to help alleviate this suffering until now.

Patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphomas (NHLs) who received frequent tests for immunoglobulin G (IgG) were less likely to experience severe infections compared with those who didn't, according to a study published in Blood Advances. Moreover, only half of patients undergo such testing.

People may be at increased risk from cancer, diabetes, cardiovascular disease, and chronic lung disease—as rising global levels of micro- and nanoplastics (MnPs) are absorbed into the human body, a new study reveals.

A wearable health monitor developed by Washington State University researchers can reliably measure levels of important biochemicals in sweat during physical exercise.

The composition of the intestinal flora can predict the chances of developing serious infections such as pneumonia. Researchers from Amsterdam UMC and the University of Turku, Finland, followed more than 10,000 people for six years. More than 600 people who had less healthy intestinal flora developed a serious infection, with this leading in some cases to death. The results of the study are publis

Two meta-analyses undertaken by the Geneva University Hospital (HUG) and the University of Geneva (UNIGE) have revealed very worrying numbers of children in Sub-Saharan Africa who are carriers of multi-resistant bacterial strains.

During hot weather—like the wave of 90-plus-degree days that Philly will experience this week—most of the public's attention is focused on skyrocketing outdoor temperatures that can cause serious medical complications such as heat stroke.

Even though COVID-19 manifests as a mild and short-lived disease in most people, some suffer extremely severe symptoms; in the worst cases, these patients die due to complications such as respiratory failure or thromboembolism. It is well-known that factors such as age and underlying medical conditions like diabetes or immunodeficiencies increase vulnerability to severe COVID-19. However, some pat

Almost 3 million people worldwide have multiple sclerosis (MS)—an autoimmune disease caused by the immune system mistakenly attacking the brain and central nervous system.

The world is becoming clogged with plastic. Particles of plastic so tiny they cannot be seen with the naked eye have been found almost everywhere, from the oceans' depths to the mountain tops. They are in the soil, in plants, in animals and they are inside us. The question is: what harm, if any, are they causing?

Philadelphia ranks No. 1 among U.S. cities for new sexually transmitted infections—STIs—according to the latest data from the Centers for Disease Control and Prevention.

It's something nearly any pathologist would welcome: a personally trained assistant that can help them identify abnormal cells in blood samples and biopsies so they can more quickly and accurately diagnose cancer or other diseases.

An international team of microbiologists and infectious disease specialists from Australia and the U.S. has found that children exposed to variants of influenza B demonstrate a bigger immune response to the same strain when they are adults.

Scientists at EPFL have achieved a significant research milestone in the field of spinal cord injuries—mapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project titled "Tabulae Paralytica."

Scientists have discovered novel immune responses that help explain how some individuals avoid getting COVID-19.

Nigerian health officials are issuing warnings over a cholera outbreak that has killed at least 30 people, many of them in the commercial capital Lagos, since the start of the year.

Fewer than 1% of people who get the flu every year get tested in part because most tests require trained personnel and expensive equipment. Now researchers have developed a low-cost paper strip test that could allow more patients to find out which type of flu they have and get the right treatment.

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. Additionally, about one-fourth of the world's population carries Mycobacterium tuberculosis without showing any symptoms, and most of these carriers do not develop the disease.

In a critical global public health development, a candidate vaccine for tuberculosis (TB) has been created using a gene-editing approach.

Researchers from the Institut d'Investigació en Atenció Primària Jordi Gol (IDIAPJGol) and the Barcelona Institute for Global Health (ISGlobal) have led a study on the effectiveness of vaccines against COVID-19 among cancer patients in Catalonia. The research, published in the journal Nature Communications, recommends administering additional doses of the vaccine among this risk population.

In low- and middle-income countries, anemia reduction efforts are often touted as a way to improve educational outcomes and reduce poverty. A new study, co-authored by a global health economics expert from the University of Notre Dame, evaluates the relationship between anemia and school attendance in India, debunking earlier research that could have misguided policy interventions.

In the US, a dairy-farm worker develops itching, blood-shot eyes. In Australia, a young girl falls ill after a foreign holiday and is rushed to hospital. In Mexico, another man, already ill and bed-bound, becomes seriously unwell and dies. Each of these recent cases was caused by a different strain of influenza virus. In each case, it was an animal virus, which should not normally have turned up i

Hospital volumes for pediatric respiratory syncytial virus (RSV) rose significantly following the pandemic, along with the need for advanced respiratory support in older children with fewer comorbidities, according to a study published online June 13 in JAMA Network Open.

A new study reveals further insight into the links between personality traits and the onset of eating disorder symptoms.

More clinical research is needed to investigate how reducing alcohol consumption in patients with alcohol-related liver disease (ALD) may slow disease progression and improve outcomes, according to an international task force of experts from more than two dozen institutions including UT Southwestern Medical Center.

While many serious cases of COVID-19 are marked by respiratory distress and dangerously low blood oxygen levels—a condition referred to as hypoxia—the occurrence of "silent or happy hypoxia" affecting a subset of patients has puzzled experts since the pandemic's onset.

Researchers have discovered that the hepatitis E virus is associated with sperm in pigs, which suggests the virus may be both sexually transmitted and linked to male infertility, according to a new study published in PLOS Pathogens.

Lizards called bearded dragons may not breathe fire, but they can be a source of one nasty infection: Salmonella.

A University of Maryland review of scientific literature suggests domestic cats can contract the rapidly evolving bird flu H5N1, potentially putting owners, veterinarians and others at risk if the virus continues to circulate unabated.

Sjögren's disease primarily affects the salivary and lacrimal glands, resulting in tissue inflammation characterized by the formation of tertiary lymphoid structures (TLS), and a loss of glandular function—resulting in dryness of the eyes and mouth, fatigue, and poor health-related quality of life.

Roughly 50 families scattered across the world share ultra-rare variants in a particular gene. Silent for years, the inherited mutations make themselves known when patients reach the fourth decade of life. Changes in vision start a cascade of symptoms. Five to 20 years later, the illness is fatal.

Globally, more than 1 million curable sexually transmitted infections (STIs) are contracted every day in people aged 15–49. These include chlamydia, gonorrhea and syphilis, among others.

Early in the pandemic, many people who had SARS-CoV-2 infection or COVID-19 began to report that they couldn't shake off their symptoms even after a month or more—unusually long for a viral infection of the upper respiratory tract—or developed new, persistent symptoms soon after the infection cleared.

Organs in the body tend to be in a set order and position. This is useful when it comes to diagnosing certain conditions. Anyone with appendicitis or gallstones, for example, will tell you exactly where the agonizing pain is. Sometimes, though, organs end up in the "wrong" place.

Earlier this week, Moderna announced positive results for its phase 3 clinical trial of a combined vaccine against COVID and influenza.

A longstanding question has nagged the COVID battle for more than four years: Why does the infection cause severe disease in older people? The question has remained despite a global cadre of medical investigators having produced some of the reasons—but not the entire story.

The international community's recent failure to conclude a global pandemic agreement leaves large gaps in our capacity to deal with the next major infectious disease emergency.

EULAR, The European Alliance of Associations for Rheumatology, updated its recommendations for systemic sclerosis (SSc) in 2023. Notably, four new therapies were added that had not been included in 2017—highlighting how fast the field is changing. New, strong evidence is now available to help better manage patients with this life-threatening condition, but gaps remain.

In 2023, The European Alliance of Associations for Rheumatology(EULAR) updated its recommendations for the treatment of systemic sclerosis (SSc), with many new inclusions around manifestations such as skin fibrosis and interstitial lung disease (ILD). However, there remains a need for better understanding of risk factors and more precise patient stratification based on organ-specific manifestation

Osteoarthritis is the most common arthritis worldwide, and has an increasing global burden of disability and health care utilization. It is also associated with various comorbidities, and this link has gained attention in recent years.

The amount of infectious H5N1 influenza viruses in raw milk rapidly declined with heat treatment in laboratory research conducted by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

In the last two years, bird flu has been blamed for the deaths of millions of wild and domestic birds worldwide. It's killed legions of seals and sea lions, wiped out mink farms, and dispatched cats, dogs, skunks, foxes and even a polar bear.

In the last two years, bird flu has been blamed for the deaths of millions of wild and domestic birds worldwide. It's killed legions of seals and sea lions, wiped out mink farms, and dispatched cats, dogs, skunks, foxes and even a polar bear.

In an animal model of Duchenne muscular dystrophy, Brazilian researchers tested a therapy that combines photobiomodulation using laser light or light-emitting diodes (LEDs) with idebenone, an antioxidant compound investigated for application in neurodegenerative diseases.

Researchers have for the first time created an integrated single-cell RNA sequencing (scRNAseq) atlas of the human periodontium, the specialized tissues in the mouth that connect teeth to the underlying bone. This atlas will help identify the unique environments that impact on the development of gum disease (periodontitis), leading to better and more precise treatments.

Since it was first detected in birds in late 2021, avian flu has killed millions of poultry and infected animals that were previously thought to be immune, including dairy cows. The FDA has documented the H5N1 virus in animals in 48 states.

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial lung disease (ILD), a condition characterized by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children. While researchers have made progress in slowing the disease in adults, the situation for children remains grim: there are currently no effective

Wastewater surveillance hit the big time during the height of the COVID-19 pandemic, when officials started using this technique to monitor local virus levels. But my colleagues and I had been exploring wastewater's promise as a public health tool years before anyone had heard of SARS-CoV-2.

South African health authorities say two people have died this week after contracting mpox, and it appears there is local transmission of the disease.

The Comoros launched a cholera vaccination drive on Thursday, according to health officials, four months after an outbreak that has killed 134 people.

Low birthweights pose major concerns in Papua New Guinea (PNG) as a leading risk factor for newborn deaths.

James Cook University researchers examining the spread of the monkeypox virus say its rapid global spread in 2022, after years of being confined to Central and West Africa, shows the need to remain vigilant against virus outbreaks wherever they occur.

For someone suffering from brittle bone disease, life is fraught with complications. The slightest misstep, a seemingly harmless fall or even one false move can be all it takes to leave them with a broken arm or leg. And chances are this will happen repeatedly, because they were born with an inherited genetic defect that makes their bones extremely brittle and is often associated with physical def

A dysfunctional enzyme may lead to nonalcoholic fatty liver disease in mice, according to a study published in Science Advances.

Two human cases of "dual mutant" strains of H1N1 flu have been reported by U.S. health officials.

Your tonsils are oval-shaped pads of tissue in the back of your throat, one on each side.

Children with acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and multisystem inflammatory syndrome (MIS-C) with severe neurological manifestations are more likely to have new neurocognitive and/or functional morbidity at hospital discharge, according to a study published online June 10 in JAMA Network Open.

A new study published in the International Journal of Nursing Studies showed that individuals with COVID-19 were more likely to die in hospitals that were chronically understaffed before the pandemic. This study is one of the first to document the continuing public health dangers of permitting so many U.S. hospitals to ration nursing care by understaffing nursing services.

Still's disease is an inflammatory disorder typically manifesting with fever, arthritis, and skin rash. It affects both children and adults, and has previously been known as systemic juvenile idiopathic arthritis and adult-onset Still's disease. Regardless of the name, people with Still's disease are burdened by life-threatening complications.

One of the big headlines from a major scientific meeting recently: The HPV vaccine not only prevents cervical cancer but reduces the risk of multiple other cancers and even pre-malignant lesions.

Bisphosphonates are the recommended first-line treatment in post-menopausal osteoporosis, with denosumab recommended second-line. Based on the length of clinical trials for bisphosphonates, these drugs are usually prescribed for 3–5 years, or longer in patients who remain at high risk, and recent recommendations suggest long-term discontinuation after this period.

People with rheumatoid arthritis (RA) tend to have different trajectories—both in how the disease evolves, and how disease states may improve over time. The frequency of pain patterns at diagnosis and over time—and their relationship with inflammation—also represents a gap in our knowledge. EULAR—The European Alliance of Associations for Rheumatology—recommends early identification and management

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses. These protective responses cause changes in blood pressure and the release of stress hormones into the blood stream. Normally, these responses are short-lived and well-controlled, but this changes after a traumatic spinal cord inju

As flowers bloom and temperatures climb, many are eager to get back outside. But while the sun may be shining, there is a dark side that can make the great outdoors not so great.

Pericytes, the multifunctional cells that work within the walls of capillaries, have been a subject of focus in the study of vascular development, cerebral blood flow, cancer, and neurodevelopment diseases.

Approximately one in every 20,000 to 40,000 children born in Japan and about one in every 100,000 throughout the world bear a mutation in the WRN gene. This gene is responsible for producing the Werner protein, which belongs to the family of human helicases and is responsible for the maintenance of genomic stability, DNA replication, repair of DNA damage, and telomere maintenance.

In September 2023, several people came down with dengue fever in Paris, France. The presence of this mosquito-borne disease was notable for two reasons. It was the most northerly outbreak ever recorded, and none of the people had traveled recently. This demonstrated it is now possible for dengue to be transmitted locally in northern Europe.

An outbreak of mpox has killed one person and infected four more in South Africa, the government said on Wednesday, adding it was trying to secure more treatment drugs as a precaution.

A new study published in the International Journal of Eating Disorders has found that mortality rates are high in patients with anorexia nervosa and nearly double in the presence of psychiatric conditions.

Chikungunya virus has caused substantial epidemics in the tropics, often with an even worse impact than dengue, but infections can also be relatively mild or even undetected. A study conducted in Brazil by researchers at the São José do Rio Preto Medical School (FAMERP) in São Paulo State shows that the virus circulated in the city silently for years. The number of cases was initially small but gr

The U.S. Preventive Services Task Force (USPSTF) recommends screening for osteoporosis for women aged 65 years and older and for postmenopausal women younger than 65 years with one or more risk factors. These recommendations form the basis of a draft recommendation statement published online June 11.

A new proposed definition for long COVID could help patients get the help they need, a new report from the National Academies of Sciences, Engineering and Medicine says.

A team of Australia's leading health researchers has developed a new "dictionary" to better predict outcomes for people who have experienced a moderate-severe traumatic brain injury (TBI). The work is published in the Journal of Neurotrauma.

As the immediate threat of COVID-19 subsides, investigating the virus's lasting impacts remains essential. A new study led by researchers at Emory AI.Health, published in Computers in Medicine and Biology, sheds light on the significant lung damage caused by severe COVID-19.

Mosquitoes have tested positive for West Nile virus in Sacramento County for the first time this year, officials said on June 10.

Cases of dengue and other mosquito-borne diseases are rising significantly in Europe as climate change creates warmer conditions that help invasive mosquitos spread, the EU's health agency warned on Tuesday.

In the United States, various minority racial and ethnic groups have reduced access to quality health care compared to their non-Hispanic white counterparts. Studies have shown that implicit biases among health care professionals stemming from unscientific notions–such as the belief that Black patients experience less pain compared to white patients–lead to mistreatment of minorities when they acc

Brazil and Mexico may be affected by a much greater spread of dengue in the years to come, according to a new study from the University of Toronto's Temerty Faculty of Medicine.

In a head-to-head study, FAPI PET/CT was found to be more predictive of progressive pulmonary fibrosis in interstitial lung disease (ILD) patients than 18F-FDG PET/CT. With heightened and extensive uptake compared to 18F-FDG, FAPI PET/CT can play an important role in identifying patients who should be monitored closely or begin preventive treatment. This research was presented at the 2024 Society

Health services should teach patients with eating disorders psychosocial skills to help more people recover and avoid relapse, according to an expert.

A more holistic definition of hearing loss by The University of Manchester and University of Nottingham researchers has revealed that 18 million people are affected, 6 million higher than previously reported using a definition from the 1980s.

Fetch the popcorn—"Love Island" is back on our screens again and that can only mean one thing: a summer of fake tans, "Turkey teeth" and underboob-baring bikinis. "Love Island" may be one of the most popular reality series on TV but it doesn't have a great track record when it comes to representating disabilities.

Cholera is a deadly disease caused by the bacterium Vibrio cholerae, associated with poor sanitation and limited access to clean water. But it has also been found in seemingly clean places, including affluent neighborhoods, hotels and restaurants with poor hygiene practices such as handling food with dirty hands and using contaminated water to wash utensils and prepare food.

The number of U.S. mpox cases has more than doubled compared with last year, and the federal Centers for Disease Control and Prevention has been urging clinicians across states to encourage vaccinations for those at risk.

An experimental 'supercharged' form of popular GLP-1 weight-loss meds could help ease fatty liver disease, a new trial suggests.

An experimental vaccine that could offer one-stop prevention for both COVID-19 and influenza is showing positive results among older adults in trials, maker Moderna announced Monday.

If tropical lands like South America or Africa are your travel destinations, getting yourself protected against yellow fever before you go is imperative, an expert says.

A two-and-a-half-year-old girl tested positive for H5N1 bird flu and needed hospital intensive care treatment in Australia after traveling to India, the World Health Organization said on Friday.

Because the majority of people living with cerebral palsy (CP) are adults, a focus on adult care in addition to pediatric and adolescent care is increasingly important to address their needs. A special issue of the Journal of Pediatric Rehabilitation Medicine, highlights topics associated with CP across the spectrum of life, including issues surrounding mental health, sexuality, and independence.

Though not at numbers seen in the 2022 outbreak, mpox cases are still circulating in the United States, largely among gay and bisexual men, new government data shows.

Among emergency department patients evaluated for an mpox-compatible rash, the prevalence of mpox is 1.5 percent, according to research published in the June 6 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

The WHO said Thursday it was awaiting the full genetic sequence data after a man died of bird flu in Mexico in the first confirmed human infection with the H5N2 strain.

The mysterious death of a man in Mexico who had one kind of bird flu is unrelated to outbreaks of a different type at U.S. dairy farms, experts say.

Neurent Medical, a company pioneering innovative non-surgical interventions to treat chronic inflammatory sinonasal diseases, today announced the publication of positive 12-month results from the CLARITY clinical trial in Laryngoscope Investigative Otolaryngology.

Long COVID continues to plague millions of Americans as the health costs of the pandemic linger four years later, a new report warns.

While mpox cases have sharply declined since the 2022 global outbreak, they continue to occur in the U.S. among gay and bisexual men who have sex with men (GBMSM), according to a UCLA-led study from EMERGEncy ID NET, a multi-site surveillance network.

A U.S. Food and Drug Administration advisory panel on Wednesday recommended updating the formula for COVID vaccines ahead of a fall campaign that will encourage Americans to get the latest shots.

How can we explain and predict human behavior? Are mathematics and probability up to the task, or are humans too complex and irrational?

At the start of the pandemic, many people living with diabetes were wondering what COVID-19 meant for them. Diabetes was already known to put people at higher risks from other infectious diseases, including flu. Would it be the same with COVID-19? At the time, all scientists could do was make educated guesses.

Low-income Black and Hispanic stroke survivors with uncontrolled hypertension had a more than two-fold reduction in blood pressure when they tracked it at home and sent their readings to a nurse case manager. The gains were in systolic blood pressure specifically at one year into the study and when compared to a similar group of patients who did not have access to a nurse.

A first-of-its kind brain organoid grown at The University of Queensland has helped researchers identify therapies that reduce the impact of COVID-19 on people with Down syndrome.

People do not need to have tested positive for the coronavirus to be considered for a diagnosis of long COVID, a new report from the National Academies of Sciences, Engineering and Medicine concludes.

A man's death in Mexico was caused by a strain of bird flu called H5N2 that has never before been found in a human, the World Health Organization said Wednesday.

A review of research to-date reveals the complex nature of revealing a diagnosis of a sexually transmitted infection (STI) to a partner ahead of engaging in sexual activity.

A new study in Heart Rhythm has examined the potential dangers of consuming energy drinks for patients with genetic heart diseases. A cohort of 144 sudden cardiac arrest survivors was examined at Mayo Clinic, of which seven patients (5%) had consumed one or more energy drinks in close proximity to their cardiac event. While the study did not prove direct causation, caution is advised, and doctors

America's poison centers are fielding increasingly severe cases that are dramatically more likely to lead to serious harm or death in both adults and children, a new study from the University of Virginia School of Medicine reveals.

Since H5N1, or avian influenza, was first identified in 1996, the Centers for Disease Control and Prevention reports four known cases of bird flu in humans in the U.S. But three of those cases are from this year, all linked to an outbreak among cows. The CDC publishes a report on bird flu that updates weekdays at 4 p.m.

Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

A malaria drug could help immune-compromised people who can't shake off babesiosis, a tick-borne parasitic infection, a new study says.

Health care providers should watch out for new and highly contagious forms of ringworm or jock itch, which are emerging as a potential public health threat, according to a pair of reports.

In a phase 2 clinical trial, a new drug under development significantly reduced both the symptoms and disease process of a condition called Sjӧgren's disease (SjD).

A novel gene therapy designed to target a form of inherited deafness has restored hearing function in five children who were treated in both ears. The children also experienced better speech perception and gained the ability to localize and determine the position of sound.

The oral microbiome is the community of bacteria that live in the mouth. It helps us digest our food and keep our mouth healthy. Changes to the composition of the oral microbiome have been linked to periodontal diseases and some cancers.

A team from the Yong Loo Lin School of Medicine at the National University of Singapore (NUS Medicine) and Monash University has engineered a COVID-19 vaccine that induced—in pre-clinical models—very long-lasting, protective immunity against SARS-CoV-2 virus with a single-shot immunization.

A team of Ochsner Health cardiologists recently published an article in the Journal of the American Medical Association (JAMA) Cardiology comparing two treatment strategies for patients with atrial fibrillation and obesity. The article, titled "Dual vs. Single Cardioversion of Atrial Fibrillation in Patients with Obesity," is based on a multi-center, patient-blinded, randomized clinical trial cond

Ret. Command Sgt. Maj. Gretchen Evans served in the United States Army for 27 years until a rocket blast in Afghanistan brought her career to an abrupt end in 2006. At just 46 years old, Evans was left with near-total hearing loss, a traumatic brain injury and post-traumatic stress disorder.

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality. The study is reported in an article published in the journal Andrology. The authors suggest that people who pla

For men with benign prostate hyperplasia, aquablation provides temporary benefits for ejaculation and continence at three months, while holmium laser enucleation of the prostate (HoLEP) has superior operation time, safety profile, and volumetric results, according to a study published online May 9 in the World Journal of Urology.

Cochlear implantation (CI) positively impacts hearing, vertigo, tinnitus, and quality of life in patients with Meniere disease (MD), according to a study published May 20 in European Archives of Oto-Rhino-Laryngology.

Even a peep of news about a new flu pandemic is enough to set scientists clucking about eggs.

For patients with type 1 or type 2 hereditary angioedema, sebetralstat provides faster times to beginning of symptom relief than placebo, according to a study published online May 31 in the New England Journal of Medicine to coincide with the annual congress of the European Academy of Allergy and Clinical Immunology, held from May 31 to June 3 in Valencia, Spain.

Excess death rates have remained high in the West for three years running since the start of the COVID-19 pandemic, finds a data analysis of 47 countries published in BMJ Public Health.

A new research paper titled "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse mode" has been published in Aging.

Metabolic dysfunction-associated steatotic liver disease (MASLD), an escalating metabolic disorder, poses a severe challenge to global health. However, our understanding of its underlying molecular mechanisms remains limited.

Research has shown that noise from airplanes and helicopters flying overhead is far more bothersome to people than noise from other modes of transportation, and a growing body of research suggests that aircraft noise is also contributing to negative health outcomes.

Charcot-Marie-Tooth (CMT) disease, a group of heritable disorders that affect the peripheral nerves, is marked by specific genetic changes. Research by the team of Prof. Ludo Van Den Bosch (VIB-KU Leuven) now reveals the effects of one such genetic cause.

As measles cases rise across the United States and vaccination rates for the MMR (measles, mumps, rubella) vaccine continue to fall, a new survey finds that a quarter of U.S. adults do not know that claims that the MMR vaccine causes autism are false.

As the H5N1 avian flu continues to spread among dairy cows in the United States, nearly 5 million doses of flu vaccine are now being prepared for possible use in humans.

Los Angeles County has detected mosquitoes carrying the West Nile virus for the first time this year.

How can someone have alcohol intoxication without consuming alcohol? Auto-brewery syndrome, a rare condition in which gut fungi create alcohol through fermentation, is described in a case study in the Canadian Medical Association Journal.

Men who illicitly used steroids to boost muscle size and physical performance and have stopped in the past year have impaired sexual function compared with men currently using steroids, according to a study being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

A recent study demonstrates that radiomics imaging analysis can effectively forecast the hearing status of patients with vestibular schwannoma. Since treatment methods, such as surgery or active surveillance, vary for these patients based on tumor size and hearing condition, predicting hearing status is crucial in planning and determining the appropriate treatment.

Physician-scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine led a nationwide study to examine the role of carpal tunnel syndrome in predicting the risk of cardiac amyloidosis.

South Sudan got its first batch of a new malaria vaccine on Friday from the U.N. health agency, an important step in efforts to battle a disease that is the biggest killer of children in this African country.

The US Food and Drug Administration on Friday approved Moderna's respiratory syncytial virus (RSV) vaccine for older adults—marking the first time any mRNA shot has been authorized against a disease other than COVID-19.

New Curtin University research has found an inpatient treatment approach can help adults with eating disorders improve not only their physical health, but also their psychological health. The research is published in the Journal of Eating Disorders.

How exactly do SARS-CoV-2 particles enter host cells? An international team led by Dr. Richard Brown from Dr. Daniel Todt's Computational Virology group at the Department of Molecular and Medical Virology at Ruhr University Bochum, Germany, together with researchers from the Paul-Ehrlich-Institut, has investigated this question.

Immunology and Infectious Disease Researcher and Senior Lecturer Dr. Hillary Vanderven is working against the clock with World Health Organization (WHO) experts reporting the next flu pandemic is a matter of when, not if.

Europe's medicines watchdog Friday gave the thumbs up for the continent's first vaccine against the mosquito-born Chikungunya virus, warning climate change could boost the spread of the disease.

More than 30,000 Australians are living with multiple sclerosis, the most common neurological cause of disability affecting young adults.

At-school vaccination may be a useful tool to increase human papillomavirus (HPV) vaccination coverage among adolescents, according to a study published in JAMA Network Open.

Amid an ongoing outbreak of bird flu in dairy cows, there's been a third case of H5N1 avian flu confirmed in a dairy worker, U.S. health officials reported Thursday.