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All articles tagged: Inflammatory disorders

Medical xPress 19 November at 02.00 PM

Colchicine no benefit for painful knee osteoarthritis

Colchicine fails to improve knee pain, function, or size of synovial effusions with painful knee osteoarthritis (OA), according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 14 to 19 in Washington, D.C.

Medical xPress 13 November at 02.00 PM

Air pollution exposure may be associated with eczema, study finds

People living in areas with higher levels of air pollution are more likely to have eczema, according to a new study published November 13, 2024 in the open-access journal PLOS ONE by Dr. Jeffrey Cohen of Yale School of Medicine, U.S..

Medical xPress 04 November at 01.28 PM

How the keto diet could one day treat autoimmune disorders by increasing anti-inflammatory compounds

Scientists have long suspected the keto diet might be able to calm an overactive immune system and help some people with diseases like multiple sclerosis. Now, they have reason to believe it could be true.

Medical xPress 31 October at 03.40 PM

Semaglutide beneficial for people with obesity, knee osteoarthritis

For individuals with obesity and knee osteoarthritis, once-weekly semaglutide yields greater reductions in body weight and pain related to knee osteoarthritis than placebo, according to a study published in the Oct. 31 issue of the New England Journal of Medicine.

Medical xPress 29 October at 11.54 AM

Internet activity reveals national allergy patterns

Complaining about your allergies online might provide valuable data to researchers. Over 25% of Americans experience seasonal allergies, but how the prevalence of seasonal allergies varies across space and time remains obscure, in part because allergies seldom warrant visits to health care providers.

Medical xPress 26 October at 07.00 AM

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

For decades, people with psoriasis have been treated in clinics with narrowband ultraviolet B phototherapy, or light therapy, to reduce sores, scales, and inflammation. Now, new research from the Perelman School of Medicine at the University of Pennsylvania shows that patients can improve their psoriasis just as well at home with phototherapy devices designed to make treatment easy to self-adminis

Medical xPress 23 October at 11.38 AM

Cellular roadmap reveals new paths to treating inflammatory bowel disease

In a world first, researchers at the Kennedy Institute, Oxford have mapped the cellular dynamics following treatment with the most commonly used advanced therapy in autoimmune diseases. They have discovered why some patients benefit from this therapy while others do not, potentially paving the way for new therapies.

Medical xPress 21 October at 06.30 PM

Study uncovers true burden of asthma in African schools and highlights need for better access to diagnosis and care

Asthma is the second most common cause of chronic respiratory deaths in the overall population of sub-Saharan Africa. The study led by researchers at Queen Mary and published in The Lancet Child and Adolescent Health, is the first of its kind to determine the true prevalence and severity of asthma in undiagnosed, yet symptomatic young people in sub-Saharan Africa.

Medical xPress 21 October at 11.29 AM

Study reveals new role for inflammatory protein in fat tissue

A new study published in Nature Communications shows that the inflammatory protein IL-1β has an important physiological function in fat tissue. Researchers at Karolinska Institutet have discovered that IL-1β helps the body manage energy storage by signaling cells to transform into new fat cells that can safely store energy.

Medical xPress 18 October at 06.10 AM

EHR order set reduces antibiotic duration in children with acute otitis media

Implementation of an electronic health record (EHR) order set increases compliance with the recommended duration of prescribed antibiotics for children with acute otitis media (AOM), according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.

Medical xPress 15 October at 11.49 AM

New test improves diagnosis of allergies

Researchers at the University of Bern and Bern University Hospital have developed a test to simplify the diagnosis of allergies. Its effectiveness has now been confirmed in clinical samples from children and adolescents suffering from a peanut allergy. The results could fundamentally improve the clinical diagnosis of allergies in the future.

Medical xPress 14 October at 09.10 AM

Anaphylaxis in infants and children: Responding to severe allergic reactions

Anaphylaxis is a rapid and severe allergic reaction. It is also a life-threatening emergency.

Medical xPress 26 September at 02.43 PM

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the quality of a patient's life and can sometimes be life-threatening.

Medical xPress 26 September at 10.34 AM

Phase II results suggest targeted therapy is effective for moderate to severe ulcerative colitis

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission.

Medical xPress 17 September at 09.59 AM

Calls for more accurate testing to prevent antibiotic allergies in children

Research from Edith Cowan University (ECU) has highlighted the need for children with a suspected antibiotic allergy to be fully assessed by drug allergy services.

Medical xPress 17 September at 06.50 AM

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Medical xPress 12 September at 05.10 PM

Gut reaction: Low levels of manganese can aggravate inflammatory bowel disease

Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of the micronutrient can exacerbate intestinal injury and inflammation.

Medical xPress 11 September at 02.00 PM

Study reveals how antibiotics contribute to inflammatory bowel disease risk

In a study published in Science Advances, Dr. Shai Bel and his research team at the Azrieli Faculty of Medicine of Bar-Ilan University have uncovered crucial insights into how antibiotic use increases the risk of inflammatory bowel disease (IBD).

Medical xPress 10 September at 01.10 PM

Refined dietary fiber may increase risk for inflammatory bowel disease

For many people, an enjoyable summer staple food is a scoop of their favorite ice cream. What they may not know is that this creamy treat often contains refined dietary fibers, such as guar gum, that could have negative effects on intestinal health, according to researchers at Penn State.

Medical xPress 09 September at 04.14 PM

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Medical xPress 05 September at 11.30 AM

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our internal health.

Medical xPress 03 September at 05.12 PM

Inflammation imprints lasting effects on intestinal stem cells, researchers discover

Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells (ISCs) that reduce their ability to heal the intestine, even after inflammation has receded. This is important because it affects ISCs' response to future challenges. The study appears in Cell Stem Cell.

Medical xPress 02 September at 12.55 PM

What's behind the large rise in food allergies among children in the UK?

The number of people in England with food allergies has more than doubled between 2008 and 2018, a new study reveals. The researchers, from Imperial College London, found that rates are highest among preschool children, with 4% having a "probable" food allergy.

Medical xPress 30 August at 04.10 PM

Dietary vitamin E may be protective against atopic dermatitis

Dietary intake of vitamin E may potentially lower the risk for atopic dermatitis, according to a study published online Aug. 9 in Skin Research & Technology.

Medical xPress 30 August at 09.42 AM

Novel pathway could lead to potential treatment for metabolic liver disease

Research from the lab of Jason Kim, Ph.D., professor of molecular medicine and medicine, identified a novel pathway in the progression of metabolic liver disease that could be targeted for potential therapies.

Medical xPress 29 August at 01.10 PM

Greater alcohol intake tied to higher gout risk

Higher consumption of alcoholic beverages is associated with a higher risk for gout among both sexes, according to a study published online Aug. 28 in JAMA Network Open.

Medical xPress 28 August at 04.27 PM

Research finds increase in allergic reactions among children in Finland, decrease in Sweden

A new registry study from Karolinska Institutet and Tampere University shows that hospital admissions due to allergic reactions in children have increased in Finland while they have decreased in Sweden. The study, published in the journal Allergy, also shows that the incidence of anaphylaxis is higher in Finland than in Sweden.

Medical xPress 28 August at 01.13 PM

Respiratory syncytial virus infection with inflammatory bowel disease ups risk for hospitalization

Adult patients with inflammatory bowel disease (IBD) and respiratory syncytial virus (RSV) infection have an increased risk for hospitalization, according to a study published online in the August issue of the American Journal of Gastroenterology.

Medical xPress 26 August at 02.37 PM

New device monitors levels of inflammation-associated C-reactive protein in real time

As inflammation is the body's natural immune response to disease or infection, it increases blood flow in the body and helps the body's cells to defend themselves against viruses, infections or cell damage. Fast diagnostics of inflammation is crucial for effective treatments, so it is extremely important to test the levels of inflammatory biomarkers in the body. Researchers from the Institute of P

Medical xPress 22 August at 05.08 PM

A potential pathway may guide new therapies for inflammatory bowel disease and other inflammatory diseases

There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a unique strain of probiotic bacteria, Bifidobacterium bifidum BB1, enhances intestinal barrier function and protects against penetration of bacteria and various harmful agents in the intestine.

Medical xPress 21 August at 12.10 AM

Obese children are more likely to develop skin conditions related to the immune system, study finds

Childhood obesity can contribute to the development of common immune-mediated skin diseases (IMSDs), such as alopecia areata, atopic dermatitis, and psoriasis, new research finds. Maintaining a healthy weight could potentially help lower the chances of developing these skin conditions.

Medical xPress 19 August at 11.45 AM

Obesity-induced inflammation increases the secretion of extracellular vesicles from adipose tissue

New research from the University of Eastern Finland sheds light on the mechanisms associating obesity with inflammation by exploring tiny membrane particles, known as extracellular vesicles, secreted by human adipocytes.

Medical xPress 16 August at 07.31 AM

Keep your gut healthy and avoid inflammatory disease, says gastroenterologist

A healthy gut helps lower your risk of developing inflammatory diseases such as inflammatory bowel disease (IBD), a chronic condition that causes inflammation in the digestive tract.

Medical xPress 15 August at 10.39 AM

Removing bile acid receptor in gut blocks intestinal inflammation, study shows

Removing a nuclear bile acid receptor that regulates glucose and lipid stability from the intestine blocks gut inflammation in mice, according to researchers at Children's Hospital Los Angeles. Their findings are published in the American Journal of Physiology-Gastrointestinal and Liver Physiology.

Medical xPress 14 August at 01.31 PM

Season of birth is associated with the development of asthma and allergic rhinitis

Season of birth, and specifically being born in autumn or winter, is associated with allergic rhinitis and asthma in Finland, a new study by the University of Eastern Finland, the University of Helsinki and Helsinki University Hospital shows. Conversely, being born in summer was associated with the lowest incidence of asthma and allergic rhinitis.

Medical xPress 09 August at 01.51 PM

Racial differences identified in frequency of biopsy for psoriasis

There are racial differences in the frequency of skin biopsy for psoriasis, indicating diagnostic uncertainty, according to a research letter published online Aug 7 in JAMA Dermatology.

Medical xPress 08 August at 12.27 PM

Study finds sclerotherapy can be successfully used by patients of all skin types, ethnic backgrounds

Chronic venous insufficiency (CVI), which impacts more than 25 million people, includes varicose and spider veins. They occur when the veins become damaged and can't work as they should.

Medical xPress 07 August at 11.00 AM

Scientists get to the bottom of COVID's worst pediatric complication

Early in the COVID-19 pandemic, some children fought off COVID with few, if any, symptoms, only to go into organ failure a few weeks later.

Medical xPress 06 August at 10.01 AM

Rare metabolic disorder can cause liver inflammation

Millions of people worldwide suffer from liver inflammation (hepatitis), an acute or chronic disease with a variety of causes. Liver inflammation frequently occurs in connection with metabolic disorders, for example fatty liver disease. Lysomal acid lipase (LAL) deficiency is a rare metabolic disorder that also causes liver inflammation.

Medical xPress 02 August at 07.40 AM

Study identifies a new disease-inducing mechanism for inflammatory bowel disease

Interleukin-10 (IL-10) is an anti-inflammatory protein that crucially controls intestinal immunity. Children with genetic defects in IL-10, or its receptors, suffer from a severe form of inflammatory bowel disease (IBD) that typically presents within the first few months of life. Symptoms are acute and include bloody diarrhea and severe abdominal pain.

Medical xPress 31 July at 01.23 PM

Methotrexate beneficial for reducing pain, stiffness in knee osteoarthritis

For patients with knee osteoarthritis (KOA), methotrexate added to usual medication is associated with a significant reduction in pain and improvement in stiffness and function at six months, according to a study published online July 30 in the Annals of Internal Medicine.

Medical xPress 26 July at 01.24 PM

Researchers highlight the limitations of a specific commercially available clinical genetic test in dermatology

Earlier this year, Department of Genetics professor Joel Sax, along with Christopher McFarland, assistant professor at the Department of Genetics and Genome Sciences, and Bryan Carroll, associate professor for the Department of Dermatology, published an article titled "Limitations of the Commercially Available Gene Expression Test in Predicting Cutaneous Squamous Cell Carcinoma Metastasis and Clin

Medical xPress 26 July at 01.09 PM

Hydroxychloroquine safe, effective treatment for anogenital lichen sclerosus: Study

Hydroxychloroquine appears to be a safe and effective treatment option for anogenital lichen sclerosus that only has mild adverse effects, according to a study published online July 19 in the International Journal of Dermatology.

Medical xPress 18 July at 04.10 PM

Air pollution exposure tied to new psoriasis

Long-term exposure to air pollution is associated with the development of new psoriasis, according to a study published online July 16 in JAMA Network Open.

Medical xPress 16 July at 02.10 PM

Current asthma at age 7 linked to chronic rhinosinusitis in middle age

Current asthma, head colds, and tonsillitis at age 7 years are associated with chronic rhinosinusitis (CRS) at midlife, according to a study published online July 10 in Allergy.

Medical xPress 10 July at 03.10 AM

Omega-3 fatty acid intake may lessen acne severity

In a study in the Journal of Cosmetic Dermatology that included 60 individuals with mild to moderate acne, following the Mediterranean diet and taking omega-3 fatty acid supplements led to significant reductions in inflammatory and non-inflammatory skin lesions, as well as improved quality of life.

Medical xPress 01 July at 12.59 PM

Psoriasis, with or without psoriatic arthritis, associated with fatigue

Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the Journal of the American Academy of Dermatology.

Medical xPress 28 June at 06.10 PM

Clinical response seen for patients with severe asthma initiating biologics

Patients with severe asthma initiating biologics exhibit clinical responses and super-responses, but 40 to 50% do not meet response criteria, according to a study published online June 22 in Allergy.

Medical xPress 28 June at 08.51 AM

Investigators propose modified criteria for identifying anaphylaxis in infants and young children

A Mass General team has developed modified criteria that may help health care professionals more accurately identify anaphylaxis, a potentially life-threatening allergic reaction, in infants and young children.

Medical xPress 26 June at 04.51 PM

Tai chi reduces risk of inflammatory disease, treats insomnia among breast cancer survivors

New research led by UCLA Health confirms that both tai chi and cognitive behavioral therapy can reduce insomnia in breast cancer survivors but also may provide additional health benefits by reducing inflammation and bolstering anti-viral defenses.

Medical xPress 25 June at 02.13 PM

Smoking and RA with obstructive pattern shows less spirometry decline

Patients who have smoked with rheumatoid arthritis (RA) and an obstructive pattern may be a unique phenotype, according to a study published online June 17 in RMD Open.

Medical xPress 25 June at 07.27 AM

Research identifies gut bacterial strains linked to inflammatory bowel disease

A new study by investigators from Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham, reveals that particular strains of gut bacteria are linked to inflammatory bowel disease (IBD), a condition that affects millions of people and is increasing in prevalence.

Medical xPress 25 June at 06.19 AM

Robotic methods help put brakes on inflammatory diseases

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

Medical xPress 21 June at 06.22 AM

New biomarker research thaws understanding of cold-induced pediatric asthma

Many parents have long known the link between lower air temperatures and asthma flare-ups in children who suffer from the disorder. But a lack of clear science behind the link has kept many feeling left out in the cold.

Medical xPress 12 June at 03.10 AM

Does inflammation in mid-life affect late-life mobility?

In a recent study published in the Journal of the American Geriatric Society, having high inflammation in midlife was associated with a clinically meaningful slower gait speed—an indicator of mobility—20 years later.

Medical xPress 11 June at 01.16 PM

Genetically healthy skin transplants show promise for rare skin disorders

Researchers from Nagoya University Graduate School of Medicine in Japan have successfully treated the skin diseases epidermolytic ichthyosis (EI) and ichthyosis with confetti (IWC) by transplanting genetically healthy skin to inflamed areas. Transplanting healthy skin to inflamed areas has been used as a treatment option for severe burn injuries.

Medical xPress 10 June at 07.00 PM

Lab-grown 'mini-guts' could help in development of new and more personalized treatments for Crohn's disease

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

Medical xPress 10 June at 10.33 AM

Gut microbes from aged mice induce inflammation in young mice, study finds

When scientists transplanted the gut microbes of aged mice into young "germ-free" mice—raised to have no gut microbes of their own—the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans. Young germ-free mice transplanted with microbes from other young mice had no such increase.

Medical xPress 08 June at 10.10 AM

Isotretinoin effective for acne in those receiving gender-affirming therapy, study shows

Isotretinoin is well tolerated and effective for individuals receiving masculinizing gender-affirming hormonal therapy who have acne, according to a study published online May 29 in JAMA Dermatology.

Medical xPress 05 June at 11.00 AM

Major cause of inflammatory bowel disease discovered

Researchers at the Francis Crick Institute, working with UCL and Imperial College London, have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing drugs.

Medical xPress 01 June at 01.20 PM

Study finds 1.5 percent ruxolitinib cream safe, effective for teens with eczema

Long-term intermittent use of ruxolitinib cream is well tolerated and provides disease control in adolescent patients with atopic dermatitis (AD), according to a study published online May 2 in the American Journal of Clinical Dermatology.

Medical xPress 27 May at 10.37 AM

Antihypertensives linked to eczematous dermatitis in seniors, study finds

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a study published May 22 in JAMA Dermatology.

Medical xPress 23 May at 09.30 AM

Parents' vaping might help spur eczema in kids

A mom or dad who vapes at home might be setting their child up for eczema, new research suggests.

Medical xPress 17 May at 11.00 AM

Link between e-cigarette use and early age of asthma onset in US adults discovered

A significant link between the use of electronic cigarettes and earlier age of asthma onset in U.S. adults was reported by UTHealth Houston researchers May 17, 2024 in JAMA Network Open.

Medical xPress 16 May at 05.03 PM

Evaluating a mobile app as a training tool to detect skin diseases

The Journal of Medical Internet Research has published the results from the first phase of the validation study on the SkinNTDs mobile app, which aims to help control neglected tropical diseases and some common skin diseases, which particularly affect countries with low per capita incomes.

Medical xPress 10 May at 11.51 AM

Could better inhalers help patients, and the planet?

Miguel Divo, a lung specialist at Brigham and Women's Hospital in Boston, sits in an exam room across from Joel Rubinstein, who has asthma. Rubinstein, a retired psychiatrist, is about to get a checkup and hear a surprising pitch—for the planet, as well as his health.

Medical xPress 25 April at 11.40 AM

Tobacco smoking reduces the odds of psoriasis improvement, study finds

Tobacco smoking is negatively associated with resolution of psoriasis symptoms, according to a study published in the April issue of Tobacco Induced Diseases.

Medical xPress 23 April at 04.05 PM

PET scans uncover smoldering inflammation in MS patients

A new study from Brigham and Women's Hospital suggests that positron emission tomography (PET) brain scans could reveal hidden inflammation in patients with multiple sclerosis (MS) who are being treated with highly-effective treatments. The findings were published in Clinical Nuclear Medicine.

Medical xPress 22 April at 03.00 PM

Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases

In a scientific breakthrough, Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

Medical xPress 17 April at 11.08 AM

Researchers find evidence a natural juice can help gut health

A team of researchers at the University of Missouri is uncovering how the juice from red cabbage, long used in traditional medicine, can alleviate inflammation-associated digestive health conditions such as inflammatory bowel disease (IBD) in mice, offering hope to the estimated 3 million Americans who suffer from IBD, including Crohn's disease and ulcerative colitis.

Medical xPress 16 April at 05.01 PM

Improving asthma control in young adults

Here's a surprising statistic: Nearly 50% of people with asthma do not take their medications as prescribed. That means they risk a flare-up of symptoms or a visit to the emergency room. Asthma researchers have studied medication adherence in children and adults to improve patient education, but rarely the population that bridges those groups: young adults.

Medical xPress 12 April at 08.56 AM

Inflammation discovery advances the fight against chronic liver disease

In a world-first, QIMR Berghofer scientists have discovered the mechanism that causes severe inflammation among millions of people with chronic liver disease.

Medical xPress 08 April at 03.35 PM

Heart-on-a-chip model used to glean insights into COVID-19-induced heart inflammation

Researchers at the University of Toronto and its partner hospitals have created a unique heart-on-a-chip model that is helping untangle the causes of COVID-19-induced heart inflammation and uncover strategies to reduce its impact.

Medical xPress 28 March at 02.42 PM

Possible new biomarker for better detection of numerous inflammatory diseases

Tryptophan is an essential amino acid, which means that it cannot be produced by the body but must be included as part of our diet. People with chronic bowel inflammation consume significantly more tryptophan than healthy people, as shown by previous research that involved members of the Cluster of Excellence "Precision Medicine in Chronic Inflammation" (PMI) at Kiel University.

Medical xPress 24 March at 04.40 PM

Bypassing oral immunotherapy buildup safe in children with food allergy

An initial phase of multifood sublingual immunotherapy (SLIT) that bypasses oral immunotherapy (OIT) buildup is safe and effective, according to a study published online Feb. 27 in the Journal of Allergy and Clinical Immunology: In Practice.

Medical xPress 20 March at 03.14 PM

Study reveals how ulcer bacteria's ability to attach to inflamed stomach is affected by pH

A study by Anna Arnqvist's research group at Umeå University reveals molecular details about the gastric pathogen Helicobacter pylori's ability to bind to an inflamed stomach and how this is controlled by the stomach's pH. An increased understanding of how H. pylori bacteria can cause a persistent lifelong infection is an important piece of the puzzle in order to ultimately identify the characteri

Medical xPress 18 March at 01.45 PM

Keeping score: Novel method might help differentiate two serious skin diseases

Your skin becomes red and spots filled with pus appear, so you visit a dermatologist. When these symptoms spread to the skin throughout the body, it is difficult for the physician to distinguish whether it is generalized pustular psoriasis (GPP) or acute generalized exanthematous pustulosis (AGEP), as both have similar symptoms. The two diseases run different courses and require different treatmen

Medical xPress 15 March at 11.40 AM

117 cases of multisystem inflammation syndrome in children identified during 2023

In 2023, 117 cases of multisystem inflammation syndrome in children (MIS-C) were reported, with 26 percent of patients having onset during August to October, according to research published in the March 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Medical xPress 13 March at 02.00 PM

Review suggests the Wim Hof method may reduce inflammation, but has mixed effects on exercise performance

The Wim Hof method may produce a beneficial anti-inflammatory response characterized by increased epinephrine levels and a reduction in pro-inflammatory cytokines, according to a systematic review published in the open-access journal PLOS ONE by Omar Almahayni and Lucy Hammond from the University of Warwick, UK.

Medical xPress 13 March at 11.10 AM

Atopic dermatitis in children tied to learning, memory difficulties

Pediatric atopic dermatitis (AD) is associated with greater odds of reported difficulties in learning and memory, but this association is driven by children with neurodevelopmental comorbidities, according to a study published online March 6 in JAMA Dermatology.

Medical xPress 12 March at 06.00 AM

Chronic stress and inflammation linked to societal and environmental impacts in new study

From anxiety about the state of the world to ongoing waves of COVID-19, the stresses we face can seem relentless and even overwhelming. Worse, these stressors can cause chronic inflammation in our bodies. Chronic inflammation is linked to serious conditions such as cardiovascular disease and cancer—and may also affect our thinking and behavior.

Medical xPress 06 March at 03.40 PM

AAAAI: Early-life day care attendance may lower risk for asthma, allergies

Early-life day care attendance may be protective against allergen sensitization, according to a study presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology, held from Feb. 23 to 26 in Washington, D.C.

Medical xPress 27 February at 06.30 PM

Poorly controlled asthma emits same quantity of greenhouse gas as 124,000 homes each year in the UK: Study

Patients whose asthma is poorly controlled account for eight times excess greenhouse gas emissions compared with those whose condition is well controlled—equivalent to that produced by 124,000 homes each year in the U.K. This result has been published online in the journal Thorax.

Medical xPress 25 February at 01.50 PM

Drug limits dangerous reactions to allergy-triggering foods, pediatric study finds

A drug can make life safer for children with food allergies by preventing dangerous allergic responses to small quantities of allergy-triggering foods, according to a new study led by scientists at the Stanford School of Medicine.

Medical xPress 22 February at 10.45 AM

Unsaturated fats can help control damaging bouts of inflammation in colitis

An overly robust immune response to usually harmless germs has been linked to colitis, a potentially severe inflammation of the colon that afflicts millions of people worldwide. A new Yale-led study not only reveals that the presence of one class of fatty acids is the hidden villain that quietly triggers this inflammation, but also found that another group of fats—unsaturated fats such as those fo

Medical xPress 25 January at 04.25 PM

Study reveals link between cannabis use and current asthma prevalence in US adolescents and adults

Asthma is more common among U.S. individuals who report cannabis use in the most recent 30 days, with the odds of asthma being significantly even greater among individuals who reported cannabis use 20 to 30 days per month, according to a new study by researchers at Columbia University Mailman School of Public Health, City University of New York and Children's National Hospital at George Washington

Medical xPress 24 January at 09.47 AM

Study identifies promising target for treating inflammatory bowel disease and colitis-induced colorectal cancers

Inflammation in the gut can trigger a doom loop of sorts. The condition messes with the sensitive relationships between food, digestive acids, microbes and the immune system in ways that can promote further inflammation and, sometimes, the eventual growth of tumors.

Medical xPress 24 January at 03.00 AM

How does climate change affect eczema?

In an analysis of all relevant published studies that assessed atopic dermatitis (also known as eczema) associated with trends in climate-related hazards due to greenhouse gas emissions, investigators found that impacts include direct effects on eczema, like particulate matter-induced inflammation from wildfires; and indirect effects, such as stress resulting from drought-induced food insecurity.

Medical xPress 19 January at 09.24 AM

Vascular changes persist after multisystem inflammatory syndrome in children, research finds

Multisystem inflammatory syndrome in children (MIS-C) may be associated with an increased risk for future cardiovascular complications due to significant persistent vascular alterations, according to a research letter published online Jan. 16 in JAMA Pediatrics.

Medical xPress 16 January at 05.16 PM

Researchers reveal Cutibacterium acnes as a potential cause of lichen striatus hypopigmentation

Lichen striatus (LS), a skin condition manifesting as linear eruptions following Blaschko's lines on the trunk or limbs of children, is often accompanied by hypopigmentation (loss of melanin or skin color). Interestingly, LS has a higher frequency of hypopigmentation compared to other skin inflammations, with up to 50% of cases that can persist for several months to even years. However, the cause

Medical xPress 16 January at 10.40 AM

Daily active commuting may lower inflammation levels

A new study, conducted by the University of Eastern Finland, the Finnish Institute for Health and Welfare, and the Finnish Institute of Occupational Health, shows that engaging in active commuting for a minimum of 45 minutes a day was associated with lower levels of C-reactive protein (CRP), a key marker of inflammation.

Medical xPress 16 January at 12.00 AM

Chronic inflammation and poverty are a 'double whammy' for mortality risk, finds study

A new study finds that people with chronic inflammation living in poverty have more than double the risk of dying from heart disease and nearly triple the risk of dying from cancer within the next 15 years. The findings of the study, led by a University of Florida College of Public Health and Health Professions researcher, are based on data representing 95 million Americans ages 40 and over.

Medical xPress 15 January at 08.50 AM

Malnutrition often seen in patients treated for inflammatory bowel disease

Some patients seen in an inflammatory bowel disease (IBD) clinic screen positive for malnutrition, according to a research letter published online Nov. 20 in Gastro Hep Advances.

Medical xPress 12 January at 08.45 AM

Diet and diverticulitis

Divertitulitis is a fairly common condition, especially as we get older. What to eat when plagued with this intestinal condition depends on where one is in the process. For reasons not yet completely understood, little pockets called diverticuli sometimes form in the lining of the digestive tract. The presence of these pouches is called diverticulosis.

Medical xPress 11 January at 01.06 PM

Eczema website delivers for patients and the NHS

A website that helps people with eczema to manage their symptoms could be saving the NHS hundreds of thousands of pounds, according to new research by the University of Southampton.

Medical xPress 05 January at 09.23 AM

Bacterial enzyme research paves the way for acne vaccine

In a groundbreaking development in the field of anti-acne therapies, a team of researchers at University of California San Diego School of Medicine has created an acne vaccine that successfully reduces inflammation in a mouse acne model. The vaccine neutralizes a specific variant of an enzyme produced by an acne-associated bacteria, while leaving the healthy bacterial enzyme intact.

Medical xPress 04 January at 01.31 PM

Transgender, gender-diverse individuals report acne-related stigma

Transgender and gender-diverse individuals report experiencing acne-related stigma, according to a study published online Jan. 3 in JAMA Dermatology.

Medical xPress 29 December at 11.16 AM

New perspectives on treating gallbladder inflammation

Ischemic cholecystitis is a form of gallbladder inflammation that occurs without gallstones or another form of external compression. It is caused by poor perfusion to the gallbladder tissue.

Medical xPress 18 December at 05.17 PM

Spike in dermatology visits for skin problems seen during summer of wildfires

New research suggests that air pollution may contribute to the development or worsening of skin conditions.

Medical xPress 13 December at 01.11 PM

Vitamin D deficiency linked to inflammation in IBD patients

Lower levels of vitamin D found in inflammatory bowel disease (IBD) patients are linked to inflammation, potentially playing a role in the disease's development, according to findings from a cross-sectional observational study published in the journal Medicine.

Medical xPress 08 December at 02.08 PM

Multinational study finds biologic therapies can control severe asthma

A study has shown that severe asthma can be controlled using biologic therapies, without the addition of regular high-dose inhaled steroids, which can have significant side effects.

Medical xPress 06 December at 03.46 PM

New findings reveal important insights into age-related nonresolving inflammation

Aging is associated with chronic, nonresolving inflammation, or "inflammaging," that can lead to tissue dysfunction. New findings reported in The American Journal of Pathology reveal insights into the cellular programs and factors that promote the resolution of inflammation during aging. These findings may lead to the development of new strategies to limit age-related organ decline.

Medical xPress 05 December at 04.30 PM

Markers of inflammation can predict 180-day mortality in cirrhosis

For patients with newly diagnosed cirrhosis, markers of inflammation can predict 180-day mortality, but not liver-related admissions, according to a study published online Nov. 16 in Scientific Reports.

Medical xPress 29 November at 04.45 PM

Research reveals risk factors for poor asthma control in children

A recent University of Alberta study is shedding more light on how perinatal health and early life events are related to asthma control in children. "Perinatal and early life factors and asthma control among preschoolers: a population-based retrospective cohort study" was published in BMJ Open Respiratory Research.

Medical xPress 22 November at 12.28 PM

Study finds early anti-inflammatory treatment is best protection for the newborn brain

A major systematic review of treatments for protecting the newborn brain from the negative effects of inflammation has found that earlier anti-inflammatory intervention is best, but it's better late than never.

Medical xPress 20 November at 01.45 PM

Few studies include photos of patients with psoriasis, finds review

Very few patients with psoriasis are depicted in scientific articles—only a fraction of those included in the research are represented in images. This is revealed by a study from the University of Gothenburg, Sweden, together with researchers from the University of Copenhagen, Denmark. The lack of images complicates communication with patients, according to the researchers.

Medical xPress 09 November at 09.00 AM

Early life exposure to broccoli sprouts may protect against colitis in inflammatory bowel disease

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice. The study was published in mSystems.

Medical xPress 07 November at 11.00 AM

Body changes detected up to eight years before inflammatory bowel disease diagnosis

Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

Medical xPress 03 November at 07.50 AM

FDA approves Wezlana for multiple inflammatory diseases

The U.S. Food and Drug Administration has approved Amgen's Wezlana (ustekinumab-auub) as a biosimilar to and interchangeable with Stelara (ustekinumab) for multiple inflammatory diseases.

Medical xPress 02 November at 06.00 AM

'Super melanin' heals skin injuries from sunburn, chemical burns

Imagine a skin cream that heals damage occurring throughout the day when your skin is exposed to sunlight or environmental toxins. That's the potential of a synthetic, biomimetic melanin developed by scientists at Northwestern University.

Medical xPress 01 November at 12.22 PM

Risk of serious infection even in low-active IBD, finds study

IBD is an umbrella term for chronic inflammatory bowel diseases, with a population prevalence of around 0.5%. The main types of IBD are ulcerative colitis and Crohn's disease. Unlike irritable bowel syndrome (IBS), IBD results in visible damage to the intestinal mucous membrane.

Medical xPress 30 October at 11.25 AM

New inflammatory mechanisms unveiled in the setting of liver disease and liver cancer

An international study involving Birmingham researchers identified for the first time how a protein found in the endothelium supports the transfer of specific immune cells, called macrophages, from the blood into the liver, causing inflammation—which can promote liver disease and liver cancer.

Medical xPress 26 October at 01.26 PM

A promising target to fight inflammatory bowel diseases

Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of the cell signaling pathways controlling the maintenance of homeostasis in the gut, leading to a chronic inflammatory response.

Medical xPress 16 October at 01.23 PM

An itching paradox—a molecule that triggers the urge to scratch also turns down inflammation in the skin

Itching can be uncomfortable, but it's a normal part of your skin's immune response to external threats. When you're itching from an encounter with poison ivy or mosquitoes, consider that your urge to scratch may have evolved to get you to swat away disease-carrying pests.

Medical xPress 12 October at 06.00 PM

Almost half of patients with skin disease suffer from sleep disturbances, global study finds

Almost half (42%) of patients with skin disease experience sleep disturbances, a major study presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2023 has revealed.

Medical xPress 11 October at 02.51 PM

Video: Psoriasis of the scalp

Dr. Dawn Davis, a dermatologist at Mayo Clinic, says psoriasis is a multisystem inflammatory disorder primarily affecting the skin. She says psoriasis is inherited, and more people might have genes that make them more likely to develop the condition.

Medical xPress 10 October at 04.21 PM

For toddlers allergic to peanuts, a tiny bit of protein therapy under the tongue could be the best approach

A three-year clinical trial has shown that the sublingual immunotherapy, or SLIT, is safe in peanut-allergic children ages 1 to 4, with a greater likelihood of desensitization and remission the earlier the treatment began.

Medical xPress 10 October at 01.53 PM

Allergenic foods do not increase risk for infants, research finds

Eggs, legumes including soya and peanuts, almonds and cashew nuts are now being introduced earlier in infant diets following revised advice in Sweden on the introduction of certain foods. However, there has been no change in the rate of food allergies or eczema in infants at the age of 18 months.

Medical xPress 29 September at 12.59 PM

Kids with eczema may need further allergy tests

Some children who have a common form of eczema should also be tested for allergic reactions because they may have a second allergic-type eczema, a new study suggests.

Medical xPress 29 September at 12.57 PM

Gut inflammation found to be caused by substance secreted by microbe

The human gut—or gastrointestinal system—where food is broken down into nutrients for the body, is an ecosystem that harbors thousands of bacteria species. While some microorganisms are harmful, many are beneficial and help keep the human body in good health. Besides bacteria, the gut microbiota also consists of other types of microorganisms, including protists, yeasts, and viruses.

Medical xPress 29 September at 11.03 AM

Study shows that the Basophil Activation Test is best biomarker for predicting allergic reactions

New research published in the journal Allergy has found that Basophil Activation Test (BAT) can be used to better detect allergies and predict the severity of allergic reactions than traditional predictions made via clinical criteria.

Medical xPress 19 September at 01.15 PM

Clinical trial recommends methotrexate for children with severe atopic dermatitis

A study led by King's College London compared the safety and efficacy of ciclosporin with methotrexate in children and young people with severe atopic dermatitis, a debilitating skin condition. They also examined whether the severity of the disease changed or returned after treatment ended.

Medical xPress 19 September at 11.50 AM

New sensor objectively measures scratching intensity

Akhil Padmanabha knows about itching. His chronic itching caused by severe eczema was so debilitating that he was hospitalized twice and had to be home-schooled during most of his high school years. Itch so impacted his life that, as an undergraduate, he contemplated becoming a psychologist so he could help chronically ill teens facing similar issues.

Medical xPress 08 September at 11.02 AM

Is it eczema or psoriasis? An expert offers advice

Eczema and psoriasis are skin conditions that can each affect a person's quality of life.

Medical xPress 04 September at 09.49 AM

Multisystem inflammatory syndrome in children: Long-term effects on mental and neurologic health

Children and adolescents who have had multisystem inflammatory syndrome in children (MIS-C) after exposure to COVID-19 are recommended to have follow-up heart function testing. A new study from Boston Children's Hospital suggests they should also be monitored for long-term neurologic and psychosocial complications.

Medical xPress 01 September at 01.00 PM

Atopic dermatitis increases risk for inflammatory bowel disease

Both children and adults with atopic dermatitis have an increased risk for inflammatory bowel disease (IBD), according to a study published online Aug. 30 in JAMA Dermatology.

Medical xPress 01 September at 10.59 AM

Scientists call for standardization of allergy tests after trials show them to be unreliable

Dr. Thimo Ruethers from James Cook University's Australian Institute of Tropical Health and Medicine (AITHM) and JCU's Tropical Futures Institute (TFI) in Singapore says that shellfish allergy affects up to 3% of the general population, is usually lifelong and commonly triggers anaphylaxis—a condition that leads to respiratory collapse and can be fatal. In Australia, shellfish allergy is the numbe

Medical xPress 29 August at 04.01 PM

Molds and yeasts in the indoor environment found to not increase the risk of developing asthma 

Fungi (molds and yeasts) in the indoor environment are not associated with an increased risk of asthma among children. This finding was made in a study conducted by the Finnish Institute for Health and Welfare (THL), which analyzed the microbiota of approximately 380 Finnish homes.

Medical xPress 29 August at 09.55 AM

Researchers discover common origin behind major childhood allergies

Several major childhood allergies may all stem from the community of bacteria living in our gut, according to a new study led by researchers at the University of British Columbia and BC Children's Hospital.