All articles tagged: Pulmonary Medicine

Despite regulations, lung screening is lacking for workers, those exposed to shrapnel, or those located near risky sites.

Use of the immunosuppressant injection has been recommended under exceptional circumstances.

Use of the immunosuppressant injection has been recommended under exceptional circumstances.

For pulmonologists and their patients, increased rates of wildfire raise questions about how best to avoid wildfire smoke harms both now and in the future.

Scoring system could improve access for hard-to-match candidates due to height and blood type.

Favorable outcomes suggested that age and transplant listing status need not be barriers.

The toxin strychnine, the primary component of the traditional Chinese medicine, may act in the STAT3 pathway, investigators speculate.

The virtual model updated data every 15 minutes, providing a dynamic predictor for patient outcomes.

The role of epigenetics — heritable phenotypic changes that don’t alter DNA sequencing — is emerging as a potential marker and target in the diagnosis and management of obstructive sleep apnea.

Research has revealed that light at night (indoors or out) disrupts circadian clocks, increases inflammation, affects cell division, and suppresses melatonin.

Life challenges make this population very difficult to treat, but interventions that take their issues into account may improve matters.

The rate of deaths from PE among patients aged 75-79 years was 44% higher than the expected rate.

In patients with COPD both with or without heart failure, AF episodes rise around the time patients are hospitalized for exacerbations, according to a study of medical device data.

The connection between respiratory infections, chronic diseases like asthma, and the gut microbiome drives research toward more effective, targeted treatments for lung diseases.

Complex, nationwide analysis included both social and environmental factors and could inform local and national policy.

Patients with AF had threefold higher risk for shock, bleeding complications, and all-cause mortality when undergoing ultrasound-assisted catheter-directed thrombolysis.

As patients with CF live longer due to dramatic improvements in disease management, there will be a greater need for cardiovascular screening and management, investigators said.

The surprise finding hints that anti–acid reflux therapy may provide benefit in COPD, possibly by reducing micro-aspirations, but the results are only tentative.

The possible benefit follows similar observations in diabetes, heart failure, and kidney disease, but the potential mechanism remains unknown.

Mechanical thrombectomy was associated with better survival outcomes across patient risk categories and time-to-treatment.

Location of pulmonary embolism may be an important factor in its clinical impact.

Doctors are learning that empathy, storytelling, and patient-centered approaches — rather than just facts — are key to overcoming vaccine hesitancy and building patient trust.

Wildfire-related air pollution causes higher mortality rates than non-wildfire PM 2.5 in Europe. Experts debate if prescribed fires reduce the risk or contribute to air pollution.

Injectable biologic was approved as adjuvant therapy to inhaled medications.

AI models accurately detected lung disease in infants and outperformed trainee doctors in diagnosing respiratory issues, offering a new tool for clinical assessments, studies found.

Data showed the need for more attention to reducing indoor volatile organic compounds in daycare settings.

A new dose-finding study supported the potential of the carbonic anhydrase inhibitor as an alternative to CPAP machines.

Changes to respiratory microbiota included disruption of immune mediators.

Experts identified community-based disparities and offered guidance for treatment and advocacy.

Analysis from a phase 2 study showed potential to monitor treatment response in future trials.

A study found abnormal lung perfusion in long-COVID patients with normal CT scans, highlighting pulmonary vascular issues. At ERS 2024, researchers call for further investigation into the condition.

Despite teaching, nearly 6% of inhalers could not be used without a critical error.

Persistent eosinophilia is associated with increased airway wall thickness in COPD, and detecting volatile organic compounds in patients' breath could predict exacerbations.

Improved lung function and acceptable safety endured over 5 years.

Physicians should track clinical remission in patients with asthma on biologics and monitor for EGPA symptoms, as corticosteroid tapering may unmask underlying disease, studies reported.

A deep-dive analysis of preschoolers' lungs can help pediatricians identify potential cases of asthma and responsiveness to corticosteroids.

Patients with pulmonary arterial hypertension who received bilateral lung or heart-lung transplants showed similar survival outcomes at 1 and 5 years, researchers reported.

Nearly half of the older hospitalized patients with COPD met the criteria for malnutrition.

Genetic testing can identify missed cystic fibrosis cases, while new biomarkers could improve the monitoring of inflammation and exacerbations.

At ERS 2024, experts debated systemic thrombolysis vs mechanical and surgical treatments for high-risk pulmonary embolism, with new studies challenging current standard of care.

The integration of artificial intelligence in medical practice presents a range of opportunities, but it also comes with challenges and ethical considerations.

British drugmaker GSK said on Friday that its asthma drug, Nucala, met the main goal of a late-stage study in treating patients with chronic obstructive pulmonary disease...

In a real-world population of patients with EGFR-mutant advanced lung cancer, overall survival was much worse in patients who would not have been eligible for the pivotal FLAURA trial.

Racial, ethnic, and socioeconomic disparities in lung transplantation exist. Can better data collection and donor lung preservation, and equitable distribution address them?

Short-term increases in fine particulate matter drove health risks for asthma, with lesser impact on COPD.

A pilot study examined how poor sleep might affect bodily functions.

An initiative from CVS Health was created to protect vulnerable pulmonary patients in dangerous weather conditions.

At a planned annual wholesale cost of more than $35,000, the novel therapy may be out of financial reach for many patients, analysts caution.

Researchers were encouraged by sustained improvements in patients with lower lobe disease.

Insmed said its drug candidate for a chronic lung disease helped significantly reduce the frequency of respiratory symptoms such as chronic cough in a late-stage study,...

New trial confirmed safety and efficacy of a subcutaneous add-on therapy for uncontrolled COPD.

A diverse and refractory patient population showed significant improvements within a year of starting biologic therapy.

Satellite-based systems provided important data on air pollution and its toxic components for pulmonary health and research purposes.

A majority of individuals with no reported history of COPD showed evidence of COPD symptoms.

Gas stoves produce indoor pollution that can exacerbate asthma and COPD, but it's still unclear whether they actually cause obstructive pulmonary disease.

Persons with asthma or COPD found through community outreach had improvements in lung function and quality of life over 1 year in a randomized trial.

Pulmonologists are witnessing a surge in new technologies, some of which significantly enhance the characterization of lung lesions.

Hedgehog pathway signaling inhibitor ENV-101 blocks signals that can lead to lung fibrosis and scarring and may lead to remodeling of early fibrosis.

Treatment regimens for non–small cell lung cancer were independent predictors of chemotherapy-triggered exacerbations.

Randomized multicenter trial did not support the routine use of macrolides to reduce the risk for CLD despite bacterial reduction.

Literature review highlighted the need for more health system intervention to manage climate-associated respiratory care.

NHANES data showed a significantly greater median waist circumference among patients with asthma who had asthma attacks compared with those who did not.

Stricter standards from the Mine Safety and Health Administration included monitoring dust exposure and providing health exams.

The company announced plans to settle litigation related to 2021 device recall.

New data highlighted the vulnerability of ILD patients to pneumothorax in the native lung after single-lung transplant.

Adults with COPD showed higher blood levels of the environmental pollutant furan than those without COPD.

Proof-of-concept study supported potential of drug-like small molecule to promote lung tissue repair.

OSA management may be helpful in OSA but raises concerns about access to GLP-1s and abandoning lifestyle changes.

When considering damage to the endothelium and toxicity, e-cigarettes have a negative impact like that of conventional cigarettes.

When considering damage to the endothelium and toxicity, e-cigarettes have a negative impact like that of conventional cigarettes.

Philips announced the main terms of an agreement it reached in January with the U.S. government on its new sleep apnea machines, which has already cost the company over 360...

A U.S. federal court issued a decree to restrict the production and sale of Philips' new sleep apnea machines at several facilities in the country, the Food and Drug...

Researchers are using technology similar to that of COVID-19 vaccine.

The use of mechanical thrombectomy was associated with short- and long-term improvements in pulmonary hypertension in adults with pulmonary embolism.

Control of tuberculosis in Brazil could be improved if all patients underwent early detection of isoniazid resistance before starting treatment.

Sarcopenia also predicted exacerbations in multivariate analysis.

The U.S. Food and Drug Administration on Tuesday approved Merck's treatment for adults with high blood pressure due to constriction of lung arteries, adding another...

Potential adverse events range from localized swelling to blood vessel blockage.

Drugmaker AstraZeneca said on Monday it would cap out-of-pocket costs for its inhaled respiratory products at $35 per month in the United States, following a similar move by...

Drugmaker AstraZeneca said on Monday it would cap out-of-pocket costs for its inhaled respiratory products at $35 per month in the United States from June, following a...

Boehringer Ingelheim will cap out-of-pocket costs for the company's inhaler products for a chronic lung disease and asthma at $35 per month starting June 1, the German...

The first new COPD treatment in a decade showed safety and effectiveness in a subset of patients with type 2 inflammation.

Over-the-counter option was designed for home monitoring by adults aged 18 years and older.

Increased COPD risk was associated with earlier or later menarche, miscarriage history, earlier menopause.

Data supported differences in triglycerides after a high-fat meal in women with OSA compared with men.

New feature was designed to detect early signs of sleep apnea via watch or phone.

A population-based study showed increased exacerbations in patients with COPD across multiple gabapentinoid indications.

Increased Epworth Sleepiness Scale scores and male sex were independently associated with hypothyroidism in OSA.

Evidence of increased bone loss in patients with severe obstructive sleep apnea supported the potential role of sleep-related hypoxemia on osteoporosis.

A study of NHANES data showed a U-shaped relationship that highlights the need for attention to both ends of the weight spectrum.

Indiana University lab received support from the National Institutes of Health to expand research on allergy risk factors.

No increased risk for hypertension appeared in individuals with OSA and mildly irregular sleep.

Sleep monitoring data suggested that tracking disturbances could help map blood pressure dysregulation in young patients.

Oral nitrate supplementation showed potential as an intervention to improve cardiovascular profiles in a high-risk population.

The US Food and Drug Administration noted that use of devices may cause serious injury or death, but products are not being removed at this time.

Early adenotonsillectomy improved quality of life, symptoms, behavior, and blood pressure compared with watchful waiting.

Results of a randomized trial suggest that blood eosinophil-directed prednisolone can be an option to reduce glucocorticoid use in COPD patients.

The Bashir endovascular catheter was designed to maximize thrombus reduction via a pharmacomechanical infusion.

If introduced on a large scale, an AI-assisted home stethoscope might make asthma diagnosis more straightforward and facilitate asthma monitoring, according to researchers.

Despite new measures such as cost increases and vaping bans, some members of the antismoking lobby doubt that the effort will have significant effects.

Cross-sectional study with a diverse cohort revealed no effect modification associated with Hispanic ethnicity.

Drug's novel mechanism of action raises hopes of disease-modifying activity, but long-term cost-effectiveness rests on improvement in functional status.

Adults with severe acute respiratory distress syndrome who underwent venovenous extracorporeal membrane oxygenation had similar times to weaning with prone and supine positions.

A recent study assessed a combination of aroxybutynin, which has an antimuscarinic effect, and atomoxetine, which has a noradrenergic effect, in treating OSA.

The European Medicines Agency's safety committee on Friday recommended changes to product information for all medicines that contain the ingredient pseudoephedrine to address safety concerns related to neurological and heart-related side effects.

Changes in oral microbiota caused by cigarette smoking could contribute to development of chronic health conditions.

Changes in oral microbiota caused by cigarette smoking could contribute to development of chronic health conditions.

Vivos Therapeutics said on Wednesday the US health regulator has cleared its oral device for severe obstructive sleep apnea, leading a massive rally in the company's shares before the bell.

Data from a national sample of Australian children showed worse asthma symptoms in the presence of family hardships, maternal depression, and other stressors.

A combination oral-only therapy of bedaquiline, pretomanid, and linezolid was significantly more effective than standard care in preventing unfavorable outcomes in patients with treatment-resistant tuberculosis.

The FDA said it is alerting patients of a new safety issue with machines made by the group that are used for the treatment of obstructive sleep apnea.

Reducing exposure to tobacco smoke may reduce the burden of chronic obstructive pulmonary disease, and public health measures are needed.

Data from NHANES showed a nonlinear association between serum uric acid levels and all-cause mortality and cardiovascular mortality.

The air in First Nations houses in remote northwestern Ontario contains high concentrations of biocontaminants, mold, and fine particles that increase the risk of respiratory infections.

Almost 400,000 deaths in Europe in 2021 were related to three main air pollutants and some could have been avoided if pollutants had been reduced to WHO-recommended levels.

Sanofi plans to seek US approval for its best-selling anti-inflammatory drug Dupixent to be used in the treatment of COPD after a second large trial showed significant benefits.

Advisers to the FDA said that data on Merck's chronic cough drug do not provide sufficient evidence to prove its clinical benefit for patients.

A large Canadian clinical trial has found that using small-volume tubes to collect blood samples for laboratory testing of ICU patients can reduce blood transfusions without affecting lab results.

A first-of-its-kind surgical procedure used breast implants to hold the patient's heart in place before new lungs arrived. Vaping, smoking, and lung infections led to an urgent need for double lung transplant.

Vertex Pharmaceuticals missed Wall Street estimates for third-quarter sales on Monday, hurt by weaker-than-expected demand for its older cystic fibrosis treatments.

Phytoestrogens show potential as a treatment for menopausal women with late-onset asthma that may relieve symptoms of both conditions.

Pulmonary care clinicians may be habitually relying on outdated and inaccurate race-specific reference values when evaluating respiratory impairment in persons of African and Hispanic/Latino ancestry.

The increase in emergency department visits related to asthma syndrome was especially pronounced among working-age adults.

Although the study was retrospective, it suggests that the threshold for initiating biologics could potentially be lowered for patients with uncontrolled asthma despite adequate use of inhalers.

Coexisting pulmonary hypertension may be a marker for disease severity among patients with acute respiratory distress syndrome.

Data from a study of tobacco use indicate that sexual and gender minority persons are at higher risk for asthma severity than heterosexuals.

Patients with idiopathic pulmonary fibrosis who required dose reductions had similar all-cause mortality and death rates vs patients on the full dose.

A study of firefighters who worked at the World Trade Center in New York in the aftermath of the 9/11 attacks suggests that a low-cal Mediterranean diet may protect against lung dysfunction.

The annual meeting will feature the latest in pulmonary, critical care, and sleep medicine, plus acrobatic fire dancers and a luau feast.

Adults with nonsevere community-acquired pneumonia (CAP) responded nearly equally to three first-line and alternative antibiotic regimens, based on data from more than 23,000 individuals.

Numerous unresolved questions surround PPF treatment and support.

'Cystic fibrosis has provided a framework for approaching the genetics of lung fibrosis.'

Data show sotatercept may deliver significant clinical benefits and could reshape the trajectory of this challenging disease.

A relaxed approach to maintenance therapy during the summer likely contributes to the surge in emergency department admissions for asthma that follows the reopening of schools.

Data indicate that COPD hospital admission rates have risen among relatively young people and women, challenging the view that the condition mostly affects old men who have a history of smoking.

Renowned medical professionals and experts congregated in Milan to explore the current and future prospects of diagnosing PPF.

Primary care physicians play a pivotal role in identifying patients afflicted by obstructive sleep apnea. To effectively diagnose, increasing awareness and enhancing communication are imperative.

"When it comes to chronic cough, general practitioners often feel lost."

Adaptive pharmacotherapy is a common strategy across many medical conditions, but its use in smoking cessation treatments involving skin patches has not been examined.

Philips said on Thursday it has reached a settlement to resolve one category of legal claims against it following a major recall of its sleep apnea and respiratory devices.

To assess the impact of mepolizumab on patients with comorbidities, the researchers conducted a post hoc analysis of 822 adults with severe asthma.

The hybrid meeting promises education, collaboration, and a focus on climate change for professionals in pulmonary and critical care medicine.

More and more research shows physical activity can boost lung function and ease the symptoms of asthma. But it can also trigger an asthma attack. Here’s the best approach.