MorningMed is a community of 814,300 medical professionals

We're a place where medical professionals share news and other news items to help their peers stay up to date

evalytics NPI Lookup
HealthDay 26 January at 10.02 PM

Long-Term Disability Risk Seen After Childhood Bacterial Meningitis


FRIDAY, Jan. 26, 2024 (HealthDay News) -- Childhood bacterial meningitis significantly increases the risk for having at least one of seven long-term disabilities, according to a study published online Jan. 19 in JAMA Network Open.

Salini Mohanty, Dr.P.H., from Merck & Co. Inc. in Rahway, New Jersey, and colleagues assessed the long-term risk for disabilities among individuals diagnosed with bacterial meningitis in childhood. The analysis included 36,230 Swedish individuals diagnosed with bacterial meningitis (younger than 18 years) and matched (1:9) general population controls with up to 35 years of follow-up (1987 through 2021).

The researchers found that individuals diagnosed with bacterial meningitis had a higher cumulative incidence of all seven examined disabilities (cognitive disabilities, seizures, hearing loss, motor function disorders, visual disturbances, behavioral and emotional disorders, and intracranial structural injuries), with 29.0 percent having at least one disability. The highest relative risk for cases versus controls was seen for intracranial structural injuries (hazard ratio, 26.04), hearing loss (hazard ratio, 7.90), and motor function disorders (hazard ratio, 4.65). Risks for cognitive disabilities, seizures, hearing loss, and motor function disorders were significantly higher for Streptococcus pneumoniae infection versus Haemophilus influenzae infection or Neisseria meningitidis infection. Risk for cognitive disabilities, seizures, behavioral and emotional disorders, and intracranial structural injuries were significantly higher for children diagnosed with bacterial meningitis younger than the median age (1.5 years at diagnosis).

"The relative risk of disabilities tended to be highest during the first years after a diagnosis of bacterial meningitis but remained higher during the period starting over five years after diagnosis, suggesting that bacterial meningitis has both acute and long-term consequences," the authors write.

Several authors disclosed ties to the pharmaceutical industry.

Abstract/Full Text

#Psychiatry #Pediatrics #Ophthalmology #Infectious Disease #Neurology #Otolaryngology #Meningitis, unspecified (G03.9) #Bacterial meningitis, unspecified (G00.9) #Meningococcal infection, unspecified (A39.9) #Meningococcal meningitis (A39.0) #Chronic meningitis (G03.1) #Unspecified intellectual disabilities (F79) #Meningitis due to other and unspecified causes (G03) #Severe intellectual disabilities (F72) #Family history of intellectual disabilities (Z81.0) #Mild intellectual disabilities (F70) #Moderate intellectual disabilities (F71) #Profound intellectual disabilities (F73) #Unspecified convulsions (R56.9) #Unspecified hearing loss, unspecified ear (H91.90) #Unspecified hearing loss, bilateral (H91.93) #Unspecified hearing loss (H91.9) #Conductive hearing loss, unspecified (H90.2) #Other specified hearing loss, unspecified ear (H91.8X9) #Unspecified visual disturbance (H53.9) #Visual disturbances (H53) #Other visual disturbances (H53.8) #Visual hallucinations (R44.1) #Unspecified visual loss (H54.7) #Unspecified behavioral and emotional disorders with onset usually occurring in childhood and adolescence (F98.9) #Other behavioral and emotional disorders with onset usually occurring in childhood and adolescence (F98) #Other specified behavioral and emotional disorders with onset usually occurring in childhood and adolescence (F98.8) #Unspecified disorder of adult personality and behavior (F69) #Conduct disorder, unspecified (F91.9) #Unspecified intracranial injury without loss of consciousness, initial encounter (S06.9X0A) #Unspecified intracranial injury (S06.9X) #Unspecified intracranial injury without loss of consciousness (S06.9X0) #Conductive hearing loss, bilateral (H90.0) #Unspecified hearing loss, right ear (H91.91) #Pneumonia due to Streptococcus pneumoniae (J13) #Pneumonia due to other streptococci (J15.4) #Streptococcus pneumoniae as the cause of diseases classified elsewhere (B95.3) #Sepsis due to Streptococcus pneumoniae (A40.3) #Pneumonia due to staphylococcus, unspecified (J15.20) #Hemophilus influenzae infection, unspecified site (A49.2) #Hemophilus influenzae [H. influenzae] as the cause of diseases classified elsewhere (B96.3) #Pneumonia due to Hemophilus influenzae (J14) #Unspecified infectious disease (B99.9) #Meningococcal infection (A39) #Other meningococcal infections (A39.89)
0 Likes
0 Comments

Recent Comments


  • avatar



Recent Newsletters