All articles tagged: Diabetes

Diabetes develops when the body fails to manage its blood glucose levels. One form of diabetes causes the body to not respond to insulin at all. Called Type 1 diabetes, or T1D, this autoimmune disease happens when the body's defense system mistakes its own insulin-producing cells as foreign and kills them. On average, T1D can lead patients to lose an average of 32 years of healthy life.

For patients with obesity and prediabetes, three years of tirzepatide yields substantial and sustained weight reduction and a reduced risk for progression to type 2 diabetes, according to a study published in the New England Journal of Medicine.

An advancement in diabetes treatment has been achieved by Professor Hyun-Wook Kang and his team from the Department of Biomedical Engineering at UNIST. They have developed a novel pancreatic islet macroencapsulation system designed for subcutaneous transplantation, offering a promising solution for type 1 diabetes management.

For patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a lower risk for venous thromboembolism (VTE), according to a study scheduled for presentation at the annual meeting of the American Society of Hematology, to be held from Dec. 7 to 10 in San Diego.

Periodontal (gum) disease and diabetes are locked in a grim partnership aimed at undermining your health, experts warn.

The total number of adults living with either type 1 or type 2 diabetes in the world has surpassed 800 million—over four times the total number in 1990, according to findings from a global analysis published ahead of World Diabetes Day in The Lancet. Additionally, 445 million adults aged 30 years and older with diabetes (59%) did not receive treatment in 2022, three and a half times the number in

A study conducted at the Federal University of São Paulo (UNIFESP) in Brazil has concluded that the use of monochromatic infrared light in conjunction with conventional physical therapy is a promising alternative for the treatment of peripheral diabetic neuropathy, a type of nerve damage that most often affects the legs and feet, and one of the most frequent, insidious and incapacitating complicat

A common complication linked with pregnancy, gestational diabetes increases the risk of developing metabolic disorders, such as type 2 diabetes. Yet, its effects after childbirth remain poorly understood.

Scientists at Pennington Biomedical Research Center, along with a colleague from Peking University People's Hospital in China, have been leading a special collection and have published an editorial in Frontiers in Endocrinology, emphasizing the transformative role digital health technologies play in diabetes management and prevention.

Researchers are releasing the flagship dataset from an ambitious study of biomarkers and environmental factors that might influence the development of type 2 diabetes. Because the study participants include people with no diabetes and others with various stages of the condition, the early findings hint at a tapestry of information distinct from previous research.

Impaired blood circulation in the lower limbs is a common health problem among the elderly and one of the most prominent complications of diabetes, called diabetic foot. A syndrome characterized by foot ulcers, often associated with infection, it is the leading cause of hospitalization and up to 30% of amputations.

The prevalence of diabetes was 15.8% among U.S. adults during August 2021 to August 2023, according to a November data brief published by the National Center for Health Statistics.

Nearly 16% of American adults—that's close to one in six—now has diabetes, according to the latest data from the U.S. Centers for Disease Control and Prevention.

People with diabetes face a number of health challenges related to their chronic condition, and loss of vision due to retinal damage is one of them.

In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, Finland, Germany and the United States. The international study has provided a lot of new knowledge about how the disease develops. Analysis of the samples will continue with the aim of preventing the disease.

It's estimated almost 1.9 million Australians have diabetes, and numbers are growing. Between 2013 and 2023, the total number of people known to be living with diabetes across the country rose by 32%.

Use of sodium glucose cotransporter 2 (SGLT-2) inhibitor drugs to treat type 2 diabetes may also help to lower the risk of recurrent kidney stones and gout flare-ups, finds a study from Canada published by BMJ.

Vasomotor symptoms (VMS) during the menopause transition (MT) are associated with an increased risk for type 2 diabetes (T2D), according to a research letter published online Oct. 31 in JAMA Network Open.

Colorectal cancer and liver cancer are the second and fifth most common cancers in Hong Kong, respectively, and both are associated with notably high mortality rates. This underscores the urgent need to develop effective strategies to combat these formidable diseases.

Diabetes is an increasingly pervasive disease, currently affecting more than 500 million adults worldwide. Since there is as yet no cure for type 1 or type 2 diabetes, patients must regularly monitor their blood glucose levels (BGLs) to keep them in check. Though BGL-measuring devices relying on painful finger pricks have been the gold standard for decades, modern technology is slowly opening door

Researchers found that women who breastfed showed much lower rates of cardiovascular disease (CVD) and longer duration of breastfeeding was associated with lower risk of CVD in women with type 2 diabetes or gestational diabetes (GDM). The researchers are from the Global Centre for Asian Women's Health or GloW, based at the NUS Yong Loo Lin School of Medicine (NUS Medicine) and Harvard T.H. Chan Sc

Researchers at Centro per le Malattie Endocrine e Metaboliche, Italy, have found that a single 30-minute aerobic exercise session significantly reduced 1-hour post-load plasma glucose levels and improved insulin sensitivity in young, healthy adults. Participants showed improvements in glucose metabolism following a single bout of physical activity, indicating potential benefits in managing and pre

Since the discovery of human iPS cells, a principal goal for researchers worldwide has been to use them for various medical applications, including cell therapy. Among different human diseases, type 1 diabetes mellitus (T1DM) has been a top priority for cell therapy development.

Scientists from the University of Leicester have discovered that tuberculosis disrupts glucose metabolism in the body.

Patients with comorbid diabetes have an elevated risk for lower extremity amputation (LEA) at all stages of chronic kidney disease (CKD) compared with patients without diabetes, according to a study published online in the November issue of Journal of Diabetes and Its Complications.

Consuming more ultra-processed foods—from diet sodas to packaged crackers to certain cereals and yogurts—is closely linked with higher blood sugar levels in people with type 2 diabetes, a team of researchers in nutritional sciences, kinesiology and health education at The University of Texas at Austin have found.

Pediatric patients aged 10 to 19 years old diagnosed with COVID-19 have a higher risk of new-onset type 2 diabetes within six months compared to those diagnosed with other respiratory infections, according to researchers at Case Western Reserve University School of Medicine.

Patients aged 10 to 17 years who are prescribed glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are more likely to have comorbid type 2 diabetes, high body mass index, and a previous metformin prescription, according to a research letter published online Oct. 16 in JAMA Network Open.

A modified insulin that can prevent sudden drops in blood sugar has been demonstrated in laboratory experiments and animal models, reports a paper in Nature. This could provide a more flexible way to supplement insulin for individuals with diabetes and reduce sudden drops in blood glucose.

A groundbreaking discovery has recently brought hope to millions of people living with type 1 diabetes around the world. In a world first, scientists have successfully used stem cell therapy to reverse type 1 diabetes in a woman.

Groundbreaking research presented at UEG Week 2024 reveals a promising new treatment strategy for type 2 diabetes (T2D) that could significantly reduce or even eliminate the need for insulin therapy.

The role of the adapter protein PICALM (phosphatidylinositol-binding clathrin assembly protein) in the development of Alzheimer's disease is well documented. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), the German Center for Diabetes Research (DZD), ETH Zurich and the University of Cambridge have now for the first time studied the role of PICALM in white adip

GLP1RA agonists have been increasing in popularity for treating obesity and type 2 diabetes.

Mount Sinai researchers have published a study that shows a link between prediabetes among young people and adverse pregnancy outcomes later in life. The findings, published in JAMA Network Open on September 24, could alter how doctors routinely screen or counsel youth on blood glucose levels, and subsequently, minimize potential maternal and neonatal risks.

A new type of blood test using lipids could make it easier to identify children at risk of complications around obesity including type two diabetes, liver and heart disease, say scientists.

Type 2 diabetes mellitus (T2DM) is a critical public health issue, with its prevalence expected to rise sharply worldwide. Recent evidence points to environmental pollution, specifically exposure to hazardous chemicals like styrene and ethylbenzene, as a contributing factor for the disease.

For the first time, scientists have found that proteins from bacteria can trigger the immune system to attack insulin-producing cells, leading to the development of type 1 diabetes.

Leveraging rapid technological advances for human health is a global trend, driving the rise of biomedical engineering research.

When screening pregnant women for gestational diabetes, casual blood glucose testing misses 70% of the cases. This Kobe University study should encourage obstetricians to depend on more reliable tests to help prevent pregnancy complications and the development of type 2 diabetes in mothers and children.

A Cleveland Clinic research team has published the first study assessing the independent real-world impacts of weight loss and blood sugar control on clinical outcomes in people with type 2 diabetes treated with antidiabetic medications, and specifically with GLP-1RAs (the class of drug that includes Ozempic and Wegovy).

Semaglutide and tirzepatide treatment lead to significant weight loss and improve blood sugar control in individuals with type 1 diabetes (T1D) who are living with overweight or obesity, research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) held in Madrid, Spain (9–13 September) has found.

A series of case reports to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD), held in Madrid (9–13 Sept), describe how a technology giving insulin doses informed by an insulin pump algorithm helped three adults with type 1 diabetes better manage their blood sugars, enabling them to lead more active lives, and even run marathons.

Automated insulin delivery systems have, for the first time, been tested for people with type-one diabetes and end-stage kidney disease. The results found that they were safe and able to offer improvements in managing the patient's blood glucose.

Scientists at the Medical College of Georgia at Augusta University are searching for a new treatment target for a common complication of diabetes that can cause retinal blood vessels to break down, leak, or become blocked.

Swiftly achieving glycemic control after a diagnosis of gestational diabetes can bring the baby's risk of obesity in childhood down to a level similar to that of children whose mothers did not have gestational diabetes, according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September).

Restricting the eating window to eight hours a day significantly improves blood glucose control in adults at risk of type 2 diabetes irrespective of whether it is earlier or later in the day, according to a randomized crossover trial presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD), held in Madrid (9–13 Sept).

Gum disease is more common in individuals with microvascular complications of diabetes, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) and published in The Journal of Dental Research has found.

New research presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9–13 Sept), highlights the potential of using voice analysis to detect undiagnosed type 2 diabetes (T2D) cases.

Patients who are being treated with systemic glucocorticoids are more than twice as likely to develop diabetes as those not receiving the treatment, the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) will hear.

Night owls have a higher BMI, larger waists, more hidden body fat and are almost 50% more likely to develop type 2 diabetes (T2D) than those who go to bed earlier, shows new research to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September).

While diabetes patients are categorized into two groups, either type 1 or type 2, no two patients are the same. The simple categorization often does not portray the disease and its many presentations, especially within different populations. For this reason, diabetes researchers and clinicians have emphasized the importance of increasing the understanding of diabetes subtypes.

There is an association between genetically predicted increased insulin concentrations and decreased concentrations of circulating lipoprotein(a) (Lp[a]), according to a study published online Aug. 29 in Cardiovascular Diabetology to coincide with the European Society of Cardiology Congress 2024, held from Aug. 30 to Sept. 2 in London.

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, and diabetes develops.

Insulin can be a critical part of managing diabetes, but patients may not know all the ins and outs of using the medication effectively.

New trials are showing how the blockbuster diabetes and weight-loss meds Ozempic and Wegovy can boost health in even more ways.

A pioneering clinical trial conducted at Sheba Medical Center, Tel Hashomer, and Ben-Gurion University of the Negev has demonstrated that consuming Mankai—a novel cultivated aquatic plant—after meals can significantly lower blood sugar levels in patients with diabetes. The study found that Mankai's impact on reducing blood sugar levels is comparable to that of some medications.

As part of its ongoing exploration of vocal biomarkers and the role they can play in enhancing health outcomes, Klick Labs published a new study in Scientific Reports today—confirming the link between blood glucose levels and voice pitch and opening the door to future advancements in non-invasive glucose monitoring for people living with type 2 diabetes.

Type 2 diabetes and prediabetes are associated with accelerated brain aging, according to a new study from Karolinska Institutet in Sweden published in the journal Diabetes Care. The good news is that this may be counteracted by a healthy lifestyle.

While you're likely familiar with type 1 and type 2 diabetes, you've probably heard less about type 1.5 diabetes.

The U.S. Food and Drug Administration on Monday approved the expanded use of an automated insulin pump system to include those with type 2 diabetes.

Recent research published in the journal Diabetes sheds new light on the cellular mechanisms causing insulin resistance in type 2 diabetes, a disease affecting more than 1.2 million people in Quebec alone.

Bioactive compounds like polyphenols and their health benefits have long captured public attention and interest. Commonly present in plant-based food like fruits, vegetables, seeds, coffee, and tea, polyphenols have a strong bitter taste, and in the normal course of a day, are excreted by our body due to poor absorption.

A new study has revealed the best types of exercise for patients with type 1 diabetes.

Type 2 diabetes increased by almost 20% between 2012 and 2022, according to a new study from the University of Georgia published in Diabetes, Obesity and Metabolism.

Tirzepatide, the blockbuster GLP-1 medicine known as Mounjaro for diabetes and Zepbound for weight loss, cut the odds that an obese, prediabetic person will develop diabetes by 94%, a new trial shows.

New research finds a combination of drugs improves weight loss, glucose control and insulin resistance better than either drug alone. Using two diabetes medications together, such as a semaglutide like Ozempic or Rybelsus, with a second, newer class of drug, may offer a noninvasive solution to help people with type 2 diabetes lose weight. This could also help them manage their condition without th

Automated multiorgan computed tomography (CT), including visceral fat, can predict diabetes and associated cardiometabolic conditions, according to a study published online Aug. 6 in Radiology.

Individuals are less likely to have type 1 diabetes if their mother has the condition than if their father is affected, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.

Females' and males' muscles differ in glucose and fatty acid handling—but regular physical activity quickly triggers similar beneficial metabolic changes in the muscles of both sexes, new research to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9–13 September) has found.

A team of researchers from the University of California, Los Angeles (UCLA), Texas A&M University (TAMU), and Florida International University (FIU) have unveiled a groundbreaking innovation in diabetes management with the development of a novel continuous glucose monitoring (CGM) system.

Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) and the German Center for Diabetes Research (DZD) have published a study in Diabetes & Metabolism that sheds light on the molecular adaptations occurring in skeletal muscle following bariatric surgery, particularly in individuals with and without type 2 diabetes.

Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with lower rates of hyperkalemia and a lower rate of renin-angiotensin system inhibitor (RASi) discontinuation compared with treatment with dipeptidyl peptidase-4 inhibitors (DPP-4is) among patients with type 2 diabetes (T2D), according to a study published online Aug. 12 in JAMA Internal Medicine.

Higher intake of heme iron, the type found in red meat and other animal products—as opposed to non-heme iron, found mostly in plant-based foods—was associated with a higher risk of developing type 2 diabetes (T2D) in a new study led by researchers at Harvard T.H. Chan School of Public Health. While the link between heme iron and T2D has been reported previously, the study's findings more clearly e

For patients with type 2 diabetes, treatment with tirzepatide (a dual glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptor agonist) is associated with lower risks for all-cause mortality and adverse cardiovascular and kidney events compared with glucagon-like peptide 1 receptor agonist treatment (GLP-1 RA), according to a study published online Aug. 12 in JAMA Network

A behavioral intervention designed to support weight loss can yield remission of type 2 diabetes, according to a study published online Aug 5 in The Lancet Diabetes & Endocrinology.

Women with type 2 diabetes (T2D) have higher bone mineral density (BMD) and better bone microarchitecture, but poorer physical function than women without diabetes, according to a study published online Aug 7 in JAMA Network Open.

In my youth, I remember several people I knew tried a popular diet based around liquid meal replacements. One delicious, nutritious milkshake for breakfast, one for lunch—and by tea time they were ready to chew off their own arm with hunger.

Researchers have developed an inexpensive bandage that uses an electric field to promote healing in chronic wounds. In animal testing, wounds that were treated with these electric bandages healed 30% faster than wounds treated with conventional bandages.

For individuals newly diagnosed with type 2 diabetes mellitus (T2DM), both short and long sleep duration are associated with microvascular disease, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.

A new study from the University of Eastern Finland is the first in the world to show that a healthy diet and regular exercise reduce the risk of type 2 diabetes even in individuals with a high genetic risk. In other words, everyone benefits from lifestyle changes, regardless of genetic risk.

For individuals with prediabetes, a digital diabetes prevention program (d-DPP) is cost-effective compared with an in-person lifestyle intervention for preventing the development of type 2 diabetes (T2D), according to a study published online July 26 in Diabetes, Obesity and Metabolism.

The risk for progression to type 1 diabetes (T1D) is significantly higher in antibody-positive males compared with females, with age differences in risk trajectories, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.

Analysis of CT scans in people who undergo imaging for health screening can identify individuals at risk of type 2 diabetes, according to a study published today in Radiology. Researchers said the findings underscore CT's value in opportunistic imaging—the use of information from routine imaging examinations to learn more about a patient's overall health.

In a first-of-its-kind study, a cohort of researchers, led by the University of Colorado Anschutz Medical Campus, evaluated the effects of state-level insulin out-of-pocket costs across states and payers and over time.

For individuals with type 2 diabetes, long-term low-carbohydrate diets (LCD) are efficacious for treatment of dyslipidemia but do not affect glycemic control, according to a review published online July 24 in the Journal of Diabetes Investigation.

People taking compounded versions of Ozempic have been overdosing on the drug, the U.S. Food and Drug Administration warns.

For patients with type 2 diabetes mellitus (T2DM) and tobacco use disorder (TUD), new use of semaglutide is associated with lower risk of TUD-related health care measures compared with other antidiabetes medications, according to a study published online July 30 in the Annals of Internal Medicine.

Adults with diabetes who meet the recommended guidelines for physical activity may offset the risk of mortality that is associated with excessive sitting time, according to a new study at Columbia University Mailman School of Public Health. This is the first study to show that getting adequate exercise can counteract the elevated risk of mortality associated with sitting for long periods of time e

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD; Madrid, 9–13 September) shows that a child is almost twice as likely to develop type 1 diabetes (T1D) if their father has the condition, than if their mother has the condition.

In patients with diabetes and established diabetic retinopathy (DR), treatment with glucagon-like peptide 1 receptor agonists (GLP1RAs) is associated with increased risks of DR progression compared with sodium-glucose cotransporter 2 inhibitors (SGLT2is), according to a study published online July 19 in Diabetes, Obesity and Metabolism.

A study surveying advances in diabetes pathogenesis and treatment explores the complex factors contributing to the onset and progression of the disease, suggesting that an understanding of these dynamics is key to developing targeted interventions to reduce the risk of developing diabetes and managing its complications.

Current medical guidelines recommend that people in a preliminary stage of type 2 diabetes lose at least 7% of their body weight in order to prevent manifest diabetes. In an article in Nature Reviews Endocrinology, diabetes experts Prof. Andreas Birkenfeld and Prof. Viswanathan Mohan advocate glycemic remission (normalization of blood sugar regulation) as a prevention goal for people with prediabe

New research to be presented at the Annual Meeting of the European Association for Study of Diabetes (Madrid, Spain, 9–13 September) shows that the risk of developing type 1 diabetes (T1D) decreases markedly in girls after the age of 10 years, while the risk in boys stays the same.

Many people living with diabetes use continuous glucose monitors (CGMs) to track their blood sugar levels. These small devices, often attached to the back of your upper arm or abdomen, send data to an app on your phone. This allows you to see, in near real-time, how your blood sugar levels spike or drop depending on what you eat or how active you have been.

Investigators at Cedars-Sinai and other institutions conducted a nationwide, population-based study to identify trends in the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs)—prescription medications sold under popular drug names like Ozempic and Wegovy—in the United States.

Persistently unhealthy sleep, either not enough or too much, is associated with a significantly increased risk of type 2 diabetes in a racially and economically diverse adult population, an international team of researchers has reported.

As people with diabetes age into Medicare, they face increased quarterly out-of-pocket costs for medication, according to a study published online July 9 in JAMA Network Open.

Getting consistent sleep could help stave off type 2 diabetes, new research suggests. A study led by investigators at Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, analyzed sleep patterns over the course of seven nights and then followed participants for more than seven years.

For older adults with type 2 diabetes (T2D), use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is not associated with a significantly increased risk for suicidal ideation and behaviors, according to a study published online July 16 in the Annals of Internal Medicine.

A study conducted at the University of Eastern Finland found distinct signatures in CD8+ T cells in blood samples from children with newly diagnosed type 1 diabetes and in autoantibody-positive children who later developed type 1 diabetes. The study was published in the journal Diabetes.

Swiss pharmaceutical giant Roche said Tuesday it would soon begin marketing a device that uses artificial intelligence to predict possible low blood sugar events during the night and thus help sufferers of diabetes sleep without worry.

New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer additional protection against heart and kidney disease in patients with diabetes. The findings were published today in The Lancet Diabetes & Endocrinology and presented in May at the 61st European Renal Association Congress in Stockholm

How does our body control blood sugar so precisely? An international team led by Prof. Nikolay Ninov at the Center for Regenerative Therapies Dresden (CRTD), part of Dresden University of Technology, brought us a step closer to the answer. They found a special group of "first responder" cells in the pancreas that are crucial for triggering blood sugar response.

A team from the Icahn School of Medicine at Mount Sinai has developed the most comprehensive epidemiological dataset for youth diabetes and prediabetes research, derived from extensive National Health and Nutrition Examination Survey (NHANES) data collected from 1999 to 2018.

When it comes to managing blood sugar levels, most people think about counting carbs. But new research from the University of British Columbia shows that, for some, it may be just as important to consider the proteins and fats in their diet.

Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study published online June 26 in JAMA Network Open.

Findings from a new mouse study suggest that elenolic acid, a natural compound found in olives, can lower blood sugar levels and promote weight loss. The research could pave the way to the development of safe and inexpensive natural products for managing obesity and type 2 diabetes in people.

Researchers from Children's Hospital of Philadelphia (CHOP) revealed the mechanisms behind one particular molecule's involvement in regulating insulin sensitivity. The findings, which were translated from a preclinical animal model into a human study, may serve as the basis for a potential therapeutic target for obesity-related type 2 diabetes.

Bisphenol A (BPA) administration is associated with reduced peripheral insulin sensitivity among healthy adults, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.

People with prediabetes are advised to reduce their weight in order to prevent manifest diabetes. Researchers from the Institute for Diabetes Research and Metabolic Diseases of Helmholtz Munich at the University of Tübingen, a partner in the German Center for Diabetes Research (DZD), together with US colleagues in the renowned "Diabetes Prevention Program (DPP)," have now been able to show for the

A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).

The stress hormone cortisol appears to play a role in tough-to-treat type 2 diabetes, a new study finds.

Intermittent fasting may be a more effective intervention than drugs for people with early diabetes and either obesity or overweight, according to a study published online June 21 in JAMA Network Open.

An experimental stem cell therapy can essentially cure type 1 diabetes by restoring insulin production in some patients, early clinical trial results show.

Type 1 diabetes (T1D) diagnoses could soon be transformed with newly released guidance, developed with input from a University of Adelaide expert, outlining how to detect and monitor early-stage T1D before the point of symptom onset.

The largest and most ethnically and geographically comprehensive investigation to date of the gut microbiome of people with type 2 diabetes (T2D), prediabetes, and healthy glucose status has found that specific viruses and genetic variants within bacteria correspond with changes in gut microbiome function and T2D risk.

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs—which affect insulin-producing beta cells in the pancreas—is likely as effective as measuring the lev

Inhaled insulin could be a better option than injections or pumps for some patients with type 1 diabetes, a new clinical trial shows.

A shift in testing for and managing gestational diabetes mellitus (GDM) to much earlier in pregnancy (before 14 weeks) can prevent health complications for both the mother and baby, according to a new series published in The Lancet. Series authors challenge the current approach to GDM management—which focuses on late GDM (24 weeks+)—and call for better detection and prevention efforts alongside a

Patients with gestational diabetes show different disease progressions and therefore require personalized treatment measures. An international research team led by MedUni Vienna has now identified three subgroups of the disease with different treatment needs. The results of the study, recently published in the journal Diabetologia, could improve our understanding of gestational diabetes and signif

People with poor metabolic health are more likely to have memory and thinking problems and worse brain health, according to a new study by researchers at Oxford Population Health. The study is the largest study into metabolic and brain health to date. The paper "Association of Metabolic Syndrome With Neuroimaging and Cognitive Outcomes in the UK Biobank," is published in Diabetes Care.

Patients with diabetes face a host of potential health problems as they work to manage the chronic disease. Still, one concern that seems to weigh heavily is the risk of losing their sight through a condition known as diabetic retinopathy.

Laura Saslow, associate professor at the University of Michigan School of Nursing, has been researching the impact of different dietary patterns on type 2 diabetes for more than a decade.

A new study from orthopedic researchers at The University of Toledo has found lumbar spinal fusion procedures are far more likely to fail in individuals with diabetes.

Older Australians with diabetes who embark on caravaning holidays need to ensure they are well prepared to manage their condition while away so as not to put undue pressure on regional pharmacists, a new Flinders University study has found.

Roux-en-Y gastric bypass, a type of weight-loss surgery, kept type 2 diabetes in remission for up to 15 years and most of the weight off for up to 20 years in one of the largest long-term studies of patients undergoing the procedure. The study was presented at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2024 Annual Scientific Meeting.

A recent study sheds light on the factors that make some people more at risk of developing type 2 diabetes than others and the complex role body weight plays in the prevalence of the condition.

Food insecurity, low household income and not having private health insurance are associated with higher rates of prediabetes in adolescents, independent of race and ethnicity, according to a JAMA Network Open study by University of Pittsburgh and UPMC researchers.

For adults with advanced, insulin-treated type 2 diabetes (T2D), willingness to participate in an intensive lifestyle intervention (ILI) is very low, according to a research letter published online June 5 in Diabetes, Obesity and Metabolism.

Patients with pre-diabetes and severe obesity who had metabolic and bariatric surgery were 20 times less likely to develop full-blown type 2 diabetes over the course of 15 years than patients with the condition who did not have surgery, according to a new study presented at the American Society for Metabolic and Bariatric Surgery (ASMBS) 2024 Annual Scientific Meeting.

Bariatric metabolic surgery (BMS) is associated with a greater reduction in mortality than glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment among adults with a diabetes duration of 10 years or less, according to a study published online June 7 in JAMA Network Open.

Northwestern University researchers have developed a new antioxidant biomaterial that someday could provide much-needed relief to people living with chronic pancreatitis.

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production by the liver is triggered, a process that is still full of questions for the scientific community.

Researchers from the University of Adelaide could be closer to discovering a better way to use metformin, a common type 2 diabetes medication.

A new study reveals that aging human pancreatic beta cells display features of senescence while maintaining elevated levels of genes crucial for their function. Despite their aging status, these cells therefore exhibit an ability to release insulin in response to glucose, aiding in blood sugar regulation.

Markers of diabetes are positively associated with overactive bladder (OAB), according to a study published online April 28 in Frontiers in Endocrinology.

Widespread availability of telemedicine during the pandemic led to more equitable access to endocrinology care for patients with type 2 diabetes and heart disease, according to a study presented at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

One year after a prediabetes diagnosis, Asians were more likely to develop diabetes mellitus whereas Black patients were more likely to remain in prediabetes range, highlighting racial disparities in diabetes prevention, according to data presented at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

People of color and those who experience social vulnerability are more likely to experience worse glycemic control than their white counterparts, according to research presented at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

Testosterone appears protective against developing type 2 diabetes in men who are overweight or obese and under age 65, but not in men over that age, according to a study presented at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

Health insurance companies often deny coverage for new medications that treat children and teens with obesity and type 2 diabetes, meaning many patients who need treatment are unable to afford it, according to a study presented at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

Researchers at Edith Cowan University's (ECU's) Center for Precision Health have uncovered a significant genetic connection between type 2 diabetes and certain gut disorders, which could pave the way for more effective therapies. The work is published in the journal Communications Biology.

Specific demographic, clinical, and financial characteristics are associated with glucagon-like peptide 1 (GLP-1) receptor agonist discontinuation, according to a research letter published online May 24 in JAMA Network Open.

Diabetes mellitus (DM) is a metabolic disease characterized by pancreatic malfunction and poor production of insulin. Imagine your pancreas is a factory for insulin, a key hormone that keeps your blood sugar level. Inside this factory are tiny assembly lines called pancreatic islets.

An artificial pancreas developed by researchers at the University of Cambridge has been granted approval by the U.S. Food and Drug Administration (FDA) for use by individuals with type 1 diabetes aged 2 and older, including during pregnancy.

A recent study by WifOR Institute highlights the societal benefits of early intensified treatment for Type 2 diabetes patients in Korea. Over a 10-year period,12% more patients who started combination therapy during the early stages of the disease achieved sustained glycemic control compared to those who began with monotherapy.

Metabolic diseases, such as type 2 diabetes, are associated with compositional shifts in the human gut microbiome, including the fungal fraction called the mycobiome. But research on the mycobiome and how type 2 diabetes or its common treatment, metformin, may interact remains relatively limited despite suggestions that these fungi can influence the overall health of the microbiome, according to a

In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.

Research led by scientists from the Universities of Oxford and Edinburgh has found that early good blood glucose control can minimize the lifetime risk of diabetes-related complications, including heart attacks, kidney failure and vision loss.

An Australian-first study by the Registry of Senior Australians (ROSA) investigating the use of blood sugar-lowering medications among residents with diabetes in aged care homes nationwide, has revealed the rising use of insulin and ongoing high use of another antidiabetic drug, sulfonylureas, both associated with a heightened risk of hypoglycemia.

Use of an artificial intelligence (AI)-informed health app aids diabetes outcomes and cuts atherosclerotic cardiovascular disease (ASCVD) risk, according to a study presented at the annual meeting of the American Association of Clinical Endocrinology, held from May 9 to 11 in New Orleans.

The higher the blood sugar level in pregnant women when first diagnosed with diabetes, the higher the risk of complications around and after birth, according to research presented at the 26th European Congress of Endocrinology, held 11–14 May in Stockholm.

A team of researchers has uncovered the identity of off-target cells responsible for abnormal outgrowth and devised a method to eliminate them from iPS cell-derived pancreatic tissues in development for cell therapy against type 1 diabetes.

New research presented at the European Congress on Obesity (ECO) in Venice, Italy (12–15 May), and published in the International Journal of Obesity, could help explain why type 2 diabetes is more common in men than in women.

Gestational diabetes is associated with an increased risk for subsequent diabetes, with higher risk for gestational diabetes in second pregnancy and in both first and second pregnancies, according to a study published online May 9 in JAMA Network Open.

The U.S. Food and Drug Administration has issued a Class 1 recall—its most urgent kind—for an IOS app linked to a specific kind of insulin pump used by people with diabetes.

Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions.

Gestational diabetes is one of the most common pregnancy-related disorders, affecting approximately one-fifth of mothers giving birth in Finland, in total about 9,000 women annually. The most significant consequence of gestational diabetes is fetal macrosomia, or excessive fetal growth, which increases the risk of birth-related complications.

Adding advanced artificial intelligence to an artificial pancreas regulating type 1 diabetes is safe and improves the system's efficiency, a first-of-its-kind study from the University of Virginia Center for Diabetes Technology has found.

Millions of people around the world live with diabetes mellitus. Many of them have medication and specific dietary management approaches to help them maintain stable blood sugar levels. However, recent innovations, such as inhaled insulin, the hormone made by the pancreas, which controls blood sugar, have sparked hope for more effective and user-friendly treatments.

Blood sugar levels improve when adults with type 1 diabetes use modern insulin pumps. These are the findings of a study conducted at the University of Gothenburg. Patients are also overwhelmingly positive about the treatment.

In Europe and North America, 30 to 60% of dietary energy intake in adults comes from ultra-processed foods. An increasing number of epidemiological studies suggest a link between higher consumption levels of ultra-processed foods with higher risks of diabetes and other metabolic disorders.

Researchers at Umeå University have succeeded in imaging an entire human organ, a pancreas, in microscopic resolution. By staining different cell-types with antibodies and then using optical 3D imaging techniques to study the entire organ, their data provides a partially new picture of the pancreas.

Researchers have developed a new shoe insole technology that helps reduce the risk of diabetic foot ulcers, a dangerous open sore that can lead to hospitalization and leg, foot or toe amputations.

A new guideline from the American College of Physicians (ACP) offers clinical recommendations for the use of newer pharmacological treatments of adults with type 2 diabetes. This is an update of ACP's 2017 guideline and is based on the best available evidence for effectiveness, comparative benefits and harms, consideration of patients' values and preferences, and costs. Newer Pharmacological Treat

Grocery stores, airports and beaches aren't great places to have telehealth visits with your endocrinologist. But home can be one of the best locations, giving a doctor helpful insights into a patient's home environment, which can positively impact their care.

Researchers found that approximately one in five older Canadian adults with diabetes and no pre-pandemic functional limitations developed functional limitations for the first time during the COVID-19 pandemic. Functional limitations refer to difficulties with basic mobility-related tasks, such as walking two to three blocks, standing up from a chair, or climbing stairs. In comparison, only one in

A new study led by the Harvard Pilgrim Health Care Institute has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study. Kidney disease is a common diabetes complication and the leading cause of end-stage kidney failure. Researchers presented their work at the American Physiology Summit, held April 4–7 in Long Beach, California.

Increased sedentary time from childhood is associated with a significant increase in blood insulin concentration and therefore the risk of type 2 diabetes, a new study has found.

For people struggling with both diabetes and a common type of heart failure, the weight-loss drug Wegovy may do more for their health than help them shed pounds, new research suggests.

Heavy alcohol use may increase middle-aged adults' risk of developing Type 2 diabetes, according to research to be presented this week at the American Physiology Summit in Long Beach, California. The Summit is the flagship annual meeting of the American Physiological Society (APS).

A registry-based study from Finland identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change.

Type 1 diabetes, a chronic condition affecting millions of young individuals globally, is not exclusive to childhood. As many as half of all cases are diagnosed during adulthood, and there is a need to understand the factors contributing to the development of type 1 diabetes in adults.

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12–15 May), identifies the optimum body weight range for adults with type 2 diabetes to minimize their risk of dying from any cardiovascular disease, including heart failure, heart disease, stroke, and chronic kidney disease.

Eating more dietary fiber may help prevent type 2 diabetes by promoting beneficial gut bacteria and substances produced during metabolism, according to new research in Hispanic adults.

Lee Calladine pricks his skin with a needle up to eight times a day to give himself an injection of insulin—the hormone that keeps his type 1 diabetes in check. Without insulin, his blood-sugar levels would become dangerously high and eventually fatal.

A new study led by Harvard Pilgrim Health Care Institute and Duke University researchers found that state policies intended to reduce insulin out-of-pocket (OOP) costs for commercially insured people were not associated with increased insulin use in the overall population. However, monthly insulin OOP costs declined substantially for members in high deductible health plans with health savings acco

A new study, led by researchers from the University of Sheffield and published in BJS Open, highlights the urgent need to improve care and prevention strategies, especially for people with diabetes. It also emphasizes the urgent need to address persisting regional disparities in health care access and outcomes.

A new study published in the journal Diabetes Technology & Therapeutics has evaluated the use of tirzepatide in overweight/obese adults with type 1 diabetes. Tirzepatide is approved for managing type 2 diabetes. It improves glucose control, facilitates weight loss, and improves cardiovascular disease outcomes.

Researchers from the German Diabetes Center (DDZ) and the Robert Koch Institute have discovered a law for the relationship between mortality and age in people with diabetes: According to this law, mortality in people with diabetes in Germany constantly rises by 8.3% in males and 10.2% in females each year from the age of 30.

Although there are many differences between type 1 diabetes and type 2 diabetes, there are also similarities, such as inflammation of the insulin-producing cells. Researchers at Lund University have studied a protein called C3, which plays a central role in the body's immune system.

Diabetes is a widespread metabolic disorder affecting over 500 million adults worldwide. The most common form is type-2 diabetes (T2D), characterized by peripheral insulin resistance.

A small, long-term study of almost 500 children in Massachusetts has found that regularly drinking sugary drinks and 100% fruit juices during childhood and adolescence may be linked to a higher risk of developing Type 2 diabetes among boys than girls, according to preliminary research to be presented at the American Heart Association's Epidemiology and Prevention│Lifestyle and Cardiometabolic Scie

The global population of patients with diabetic wounds is expected to rise to between 9.1 million and 26.1 million by 2030. Diabetic wounds severely impact patients' quality of life, both physically and mentally, while also imposing a substantial economic burden on health care systems.

Researchers from Germans Trias i Pujol Research Institute (IGTP) and Ahead Therapeutics SL have been exploring a treatment based on liposome-type nanoparticles to address the autoimmunity of type 1 diabetes for years. A study recently published in the Journal of Autoimmunity examines the response of macrophages to this immunotherapy, serving as a preliminary step before clinical trials.

A landmark study by the German Diabetes Center (DDZ), published in The Lancet Diabetes & Endocrinology, sheds new light on the heterogeneity of type 2 diabetes. The researchers have employed an innovative algorithm to stratify people with type 2 diabetes using routine data and thus visualize the metabolic diversity of diabetes.

A group of researchers, led by Nanyang Technological University, Singapore (NTU Singapore), has developed a mobile application to educate individuals living with diabetes and their caregivers with knowledge of the disease and assist them in monitoring their day-to-day activities, which includes medication, physical activity, and their diet.

The FDA has warned diabetes patients not to use smartwatches or smart rings to measure their blood glucose levels. Now, obesity medicine expert Eleanor Yusupov, D.O., assistant professor at New York Institute of Technology College of Osteopathic Medicine, is sharing insight for these patients.

More than 7 million people in Germany suffer from diabetes. Research into drugs to treat this widespread disease is still difficult. Scientists led by Prof. Dr. Peter Loskill from the NMI Natural and Medical Sciences Institute and the Faculty of Medicine of the Eberhard Karls University of Tübingen have now developed a technique that significantly improves the view at the molecular and cell biolog

Research from Edith Cowan University (ECU) has found that intrauterine exposure to diabetes could be a crucial factor in the mental and psychomotor development of children, particularly those younger than 12 months.

Advances in understanding the basic biology behind the causes of diabetic retinopathy could have potential therapeutic implications later down the line. A recent paper published by the experimental ophthalmology team at the Institute of Inflammation and Aging in Nature Communications, sheds light on the mechanisms that cause eye damage in as many as 80% of people who have had diabetes for several

A KAIST research team has developed an effective wireless system that monitors the wound healing process by tracking the spatiotemporal temperature changes and heat transfer characteristics of damaged areas such as diabetic wounds.

Diabetes is a prevalent disease that, unfortunately, still has no cure. People with diabetes need to monitor their blood glucose levels (BGLs) regularly and administer insulin to keep them in check. In almost all cases, BGL measurements involve drawing blood from a fingertip through a finger prick. Since this procedure is painful, less invasive alternatives that leverage modern electronics are bei

It has been well established that people who live in rural areas in the U.S. are more likely to have diabetes and experience barriers to managing their condition compared to those who live in the suburbs and cities. Now, University of Maryland School of Medicine researchers have measured the devastating toll of this health disparity.

The U.S. Food and Drug Administration on Tuesday approved the country's first over-the-counter continuous glucose monitor for type 2 diabetes.

Adults who sleep only three to five hours a day are at higher risk of developing type 2 diabetes. This is demonstrated in a new study from Uppsala University, published in JAMA Network Open. It also shows that chronic sleep deprivation cannot be compensated by healthy eating alone.

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May) and published in Diabetologia suggests that having a low birthweight together with being overweight in young adulthood (but not childhood) contributes to the development of type 2 diabetes at an early age (59 years or younger) in men.

With more than 90,000 people in the U.S. awaiting kidney transplants, the demand exceeds the available supply—emphasizing the critical importance of identifying safe ways to broaden the kidney donor pool.

Through a series of reviews of more than 100 research papers and a three-round Delphi questionnaire, a multidisciplinary panel of 51 scientists from 18 countries have reached consensus on a pledge to end the suffering diabetes patients undergo when stigmatized or discriminated against.

Better prevention of type 2 diabetes could save both lives and money. The U.S. spends over $730 billion a year—nearly a third of all health care spending—on treating preventable diseases like diabetes.

Research targeting the insulin-inhibitory receptor, or inceptor, unveils promising avenues for beta cell protection, offering hope for causal diabetes therapy.

Bariatric surgery is more effective than medical and lifestyle modifications for achieving long-term type 2 diabetes control and remission, according to new research led by a University of Pittsburgh School of Medicine surgeon-scientist and published in JAMA.

About eight million people live with type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced "beta") in the pancreas, leading to a lack of insulin and inability to regulate blood sugar. It's not known why the body suddenly perceives its own β-cells as the enemy; some lines of evidence suggest environmental

Smartwatches and rings that claim to measure blood sugar levels for medical purposes without piercing the skin could be dangerous and should be avoided, the U.S. Food and Drug Administration warned Wednesday.

A blood test could potentially be used to assess a patient's risk of type 2 diabetes, a new study from Edith Cowan University (ECU) has found.

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

Actively managing diabetes is crucial to preventing long-term health complications, but rising costs are creating barriers to treatment.

Periodontitis (PD) is a common complication in individuals with diabetes mellitus (DM). Despite the profound implications for overall health, the complex bidirectional relationship between them lacks a comprehensive understanding so far, leaving the precise nature of their immunological connection inadequately understood. Prior studies focusing on local immune responses in gingival tissue fall sho

There is growing evidence that ongoing inflammation in the mouth, such as that seen in gum disease, in addition to causing bad breath is associated with serious diseases such as Alzheimer's disease or type 2 diabetes. Now, researchers from Osaka University have identified an easy way to fight the bacterial cause.

A multicenter, longitudinal study, co-led by investigators at the Vanderbilt Diabetes Research and Training Center (DRTC), has discovered that a small pancreas size predicts a faster progression to stage 3 type 1 diabetes (T1D), the point at which clinical diagnosis occurs.