All articles tagged: Alzheimer's disease (G30)

For patients with mild cognitive impairment (MCI) or early dementia due to Alzheimer disease (AD), comprehensive lifestyle changes may improve cognition and function, according to a study published online June 7 in Alzheimer's Research & Therapy.Dean Ornish, M.D., from Preventive Medicine Research Institute in Sausalito, Californi

A new study suggests that the APOE4 gene variant increases Alzheimer's risk more than previously thought. Individuals with two copies of the APOE4 gene are estimated to have a 60-70% chance of developing Alzheimer's by age 85. Understanding genetic risk factors can help identify those most vulnerable and inform personalized preventive measures.

Cedars-Sinai researchers identified neurons in the brain responsible for coordinating focus and short-term memory, crucial for tasks like recalling a phone number. These neurons, influenced by brain waves, aid in retaining information in working memory. The study, published in Nature, sheds light on brain processes crucial for understanding and treating conditions like Alzheimer's disease and ADHD

Recent research highlights the link between the gut microbiome and neurological disorders like Alzheimer’s. Advancements in AI are aiding in the exploration of this connection, offering potential breakthroughs in treatment. This article explores how AI is used to analyze gut-brain interactions, suggesting novel avenues for therapeutic approaches in Alzheimer’s disease.

The Allen Institute, founded by Paul Allen in 2003, embarked on an ambitious mission to map the 86 billion neurons of the human brain. This endeavor aims to decode the intricate workings of the brain and provide insights into various neurological diseases.

The FDA is conducting further safety and effectiveness assessments of Eli Lilly's experimental Alzheimer's drug. This move follows concerns raised by its advisory panel regarding the drug's efficacy and side effects. The FDA's review aims to provide more clarity on the potential risks and benefits of the medication.

Metformin, a frontline treatment for type 2 diabetes, has long been a pharmaceutical mainstay, with over 91 million prescriptions in 2021 alone. However, recent evidence suggests that metformin's efficacy extends beyond diabetes management, encompassing various conditions such as cancer, obesity, liver disease, cardiovascular issues, neurodegenerative disorders, and renal diseases. As research exp

A study suggests a possible link between mouth herpes simplex virus and dementia. Researchers found higher levels of the virus in the brains of people with Alzheimer's disease. This association raises questions about the role of viral infections in neurodegenerative conditions.

UW-Madison scientists created 3D-printed brain tissue mimicking normal function, aiding research on disorders like Alzheimer's. They horizontally layered neurons in a soft gel, enabling communication and network formation resembling human brains, offering a precise and accessible technique for studying brain conditions and drug testing.

Biogen, maker of the Alzheimer's medicine Aduhelm, announced Wednesday that it would "discontinue the development and commercialization" of the controversial drug.Biogen will return the rights to Aduhelm to Neurimmune, the private firm that invented it, the company said in a <a href="https://in

Monoclonal antibodies targeting amyloid provide small benefits on cognitive and functional scales, which do not meet the minimal clinically important difference, according to a review published in the January/February issue of the Annals of Family Medicine.Mark H. Ebell, M.D., from the University of Georgia in Athens, and colleagues con

Known risk factors account for a considerable proportion of Alzheimer disease and related dementia (ADRD) cases, with unequal distribution across race and ethnic groups, according to a study published online Jan. 17 in Neurology.Using data from the Multiethnic Cohort Study participants, Song-Yi Park, Ph.D., from the University of Hawaii

Researchers identified five distinct subtypes of Alzheimer's disease, each with unique cerebrospinal fluid protein profiles and genetic markers, suggesting the need for tailored treatments for each subtype.

Racial and ethnic minority groups are underrepresented in Alzheimer disease neuroimaging literature, according to a study published online July 25 in Communications Medicine.Aaron C. Lim, Ph.D., from the Keck School of Medicine of USC in Alhambra, California, and colleagues identified median race/ethnicity composition of Alzheimer disea

Light therapy is associated with significant improvement in sleep and psychobehavioral symptoms in patients with Alzheimer disease, according to a review published online Dec. 6 in&nbsp;PLOS ONE.Lili Zang, from Weifang Medical University in China, and colleagues conducted a systematic literature review to identify studies evaluating the

For patients with Alzheimer disease (AD), active transcranial direct current stimulation (tDCS) may improve cognitive function, according to a study published online Dec. 5 in General Psychiatry.Xingxing Li, from the Ningbo Kangning Hospital &amp; Affiliated Mental Health Centre at Ningbo University in China, and colleagues examined th

Recent research suggests that visceral fat, fat around the organs, could heighten the risk of Alzheimer's disease. This risk is present regardless of overall body weight and is linked to early brain changes related to Alzheimer's, emphasizing the importance of managing this type of fat.

Higher consumption of whole grains is associated with a slower rate of global cognitive decline, according to a study published online Nov. 22 in Neurology.Xiaoran Liu, Ph.D., from Rush University Medical Center in Chicago, and colleagues examined the association of whole-grain consumption with longitudinal change in global cognition