All articles tagged: Pure hypercholesterolemia, unspecified (E78.00)

Research suggests high niacin levels may raise heart disease risk despite its intended cholesterol benefits, cautioning against excessive niacin supplement use.

For patients with moderate-to-severe psoriasis, apremilast appears to have a neutral association with aortic vascular inflammation, generally beneficial associations with certain cardiometabolic biomarkers, and associations with reductions in visceral and subcutaneous fat, according to a study published online Sept. 21 in JAMA Dermatology.

Control of dyslipidemia and diabetes, but not hypertension, reduces the association of HIV status with cardiovascular disease (CVD), according to a study published online Jan. 16 in Clinical Infectious Diseases.Michael J. Silverberg, Ph.D., M.P.H., from Kaiser Permanente Northern California in Oakland, and colleagues conducted a retrosp

Sedentary time during childhood is tied to worse lipid profiles in young adulthood, according to a study published online Dec. 14 in the Journal of Clinical Endocrinology & Metabolism.Andrew O. Agbaje, M.D., M.P.H., from the University of Eastern Finland in Kuopio, examined the associations of sedentary time, light physical act

Genetically predicted systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-C) increase the risk for coronary heart disease (CHD), independent of age, according to a study published online Dec. 20 in PLOS ONE.Nelson Wang, M.D., Ph.D., from the University of New South Wales in Sydney, and colleagues investiga

Lipid-lowering drugs for primary prevention are associated with a significant survival benefit, but use has decreased over time, according to a study published online Nov. 16 in Circulation.Jeremy Miles, M.D., from the Montefiore Healthcare Network/Albert Einstein College of Medicine in New York City, and colleagues evaluated the pr

Two new experimental drugs show promise in treating high cholesterol by targeting specific genes. One, developed by Verve Therapeutics, significantly reduces LDL cholesterol through gene-editing, while the other, lepodisiran, effectively lowers dangerous lipoprotein(a) levels. These advances could transform treatment for those genetically predisposed to high cholesterol, pending further research o

The Portfolio diet, emphasizing plant-based foods, is linked to a lower risk of heart disease and stroke, with improved cholesterol and reduced inflammation noted in a large-scale study.

From 1999-2000 to 2017-2020, there was a reduction in the prevalence of elevated low-density lipoprotein cholesterol (LDL-C), although a considerable proportion are still unaware and untreated, according to a research letter published online Nov. 1 in JAMA Cardiology.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and collea