All articles tagged: Congenital malformation, unspecified (Q89.9)

First-trimester mRNA COVID-19 vaccine exposure is not associated with an increased risk for selected major structural birth defects, according to a study published online July 1 in JAMA Pediatrics.Elyse O. Kharbanda, M.D., M.P.H., from HealthPartners Institute in Minneapolis, and colleagues assessed whether receipt of an mRNA COV

Continuing metformin and adding insulin in early pregnancy does not significantly alter the risk for nonlive birth or live birth with congenital malformations compared with switching to insulin monotherapy, according to a study published online June 18 in the Annals of Internal Medicine.Yu-Han Chiu, M.D., Sc.D., from the Harvard T.H. C

Paternal use of metformin in monotherapy is not associated with an increased risk for major congenital malformations (MCMs), according to a study published online June 18 in the Annals of Internal Medicine.Ran S. Rotem, Sc.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues examined the association between p

Children born moderately or late preterm have increased risks for adverse neurodevelopmental outcomes, including motor, cognitive, epileptic, visual, and hearing impairments, according to a study published online Jan. 24 in The BMJ.Ayoub Mitha, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues conducted a nationw

From 2004 to 2019, there was an increase in isotretinoin use among girls and women of childbearing age in Germany, according to a study published online Jan. 25 in PLOS Medicine.Jonas Reinold, from the Leibniz Institute for Prevention Research and Epidemiology–BIPS in Bremen, Germany, and colleagues determined the age-standardized pre

The risk for congenital malformations is lower in association with buprenorphine versus methadone for opioid use disorder in pregnancy, according to a study published online Jan. 22 in JAMA Internal Medicine.Elizabeth A. Suarez, Ph.D., M.P.H., from Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues compa

Mental-behavioral disorders, congenital anomalies, and endocrine-nutritional-metabolic disorders are most strongly associated with childlessness, according to a study published online Dec. 18 in Nature Human Behaviour.Aoxing Liu, Ph.D., from the University of Helsinki, and colleagues examined 1,035,928 men born in 1956 to 1968 and wome

Exposure to air pollution during pregnancy is significantly associated with delays in neurodevelopment, according to a study published online Nov. 9 in Developmental Medicine & Child Neurology.Ping Shih, from the National Taiwan University Hospital in Taipei, and colleagues evaluated the association between ambient particulate matter

Use of second-line noninsulin antidiabetic medications (ADMs) is increasing for type 2 diabetes (T2D) in pregnancy, but use is not associated with a significantly increased risk for major congenital malformations (MCMs), according to a study published online Dec. 11 in JAMA Internal Medicine.Carolyn E. Cesta, Ph.D., from the Karolins