All articles tagged: HIV & AIDS

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

The frequency of medical board discipline for physician-spread misinformation is low, according to a study published online Nov. 12 in JAMA Network Open.Richard S. Saver, J.D., from the University of North Carolina School of Law in Chapel Hill, compared the level of professional discipline of physicians for spreading medical misinformat

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

The supply of health care professionals available to provide HIV care is expected to continue to decline over the next five years, according to research published in the November/December issue of the Journal of the Association of Nurses in AIDS Care.Andrea Norberg, D.N.P., R.N., from the Rutgers School of Nursing in Newark, New Jer

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

The supply of health care professionals available to provide HIV care continues to decline, even as the need for HIV care and prevention is expected to increase, reports a survey study in the November/December issue of the Journal of the Association of Nurses in AIDS Care.

A University of Minnesota Medical School research team has found that giving iron supplements to children living with human immunodeficiency virus (HIV) in sub-Saharan Africa could be an important first step in optimizing brain development.

Continuing their journey to develop a vaccine for HIV, Oregon Health & Science University researchers have identified a gene that could have prevented their vaccine from working in humans.

A multiomic analysis led by the IrsiCaixa AIDS Research Institute has uncovered genetic and immune mechanisms in some HIV-positive individuals, known as viremic non-progressors (VNPs), to avoid disease progression without antiretroviral therapy.

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

Affordability and mass distribution will be critical to the success of a long-lasting injectable HIV prevention drug that has proven highly effective in human trials, say global health specialists.

Preexposure prophylaxis (PrEP) use increased between 2013 and 2023, according to a research letter published online Oct. 14 in the&nbsp;Journal of the American Medical Association.Laura M. Mann, Ph.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues used the IQVIA Real-World Longitudinal Presc

Sweden has reached the UNAIDS and WHO targets for the HIV epidemic, according to a study in Eurosurveillance by researchers at Karolinska Institutet and others. According to the researchers, Sweden is the first country in the world to achieve these targets.

Indigenous communities in Latin America say they are being excluded from the global HIV/AIDS response, leaving them without access to life-saving medicines and prevention tools.

Among recipients with HIV, kidney transplantation from donors with HIV is noninferior to that from donors without HIV, according to a study published online Oct. 16 in the New England Journal of Medicine.Christine M. Durand, M.D., from Johns Hopkins University School of Medicine in Baltimore, and colleagues compared transplantation of

It is just as safe and effective for people with HIV in need of kidney transplantation to get their organ from donors who are also HIV positive as it is from donors who are not infected with the virus, a new study shows. Survival rates for organ recipients one and three years after the procedure were the same for donors with or without HIV. Also, risks of serious side effects, such as infection, f

People assigned male at birth who belong to a sexual or gender minority group were twice as likely to use methamphetamine following an HIV diagnosis, according to a study published in the Proceedings of the National Academy of Sciences.

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

For people with HIV (PWH) with low-to-moderate atherosclerotic cardiovascular disease (ASCVD) risk, metabolic risk factors contribute to new-onset diabetes mellitus (DM) among those treated with pitavastatin or placebo, according to a study published online Oct. 8 in the Annals of Internal Medicine.Kathleen V. Fitch, from Massachusetts G

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

As the old saying goes, bad news travels fast. Research shows that saying holds true when it comes to young men discussing HIV on social media. An analysis of viral tweets from young men and adolescents, the most at-risk group for new infections in the United States, revealed a wider propagation and greater audience engagement for tweets entailing a negative message—particularly, tweets using humo

At a pharmacy in Iowa, a 42-year-old Black gay man couldn't find a medication he needed. The pharmacist, a white woman, told him they didn't stock that medication. But while he waited to pay for his other purchases, he saw another customer place the medication he just asked for on the counter.

One major reason why it has been difficult to develop an effective HIV vaccine is that the virus mutates very rapidly, allowing it to evade the antibody response generated by vaccines.

Through decades of pioneering work on fighting the spread of infectious diseases such as HIV, South African public health power couple Quarraisha and Salim Abdool Karim are credited with saving thousands of lives.

Emory researchers are the first to show unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The success of this immune-based approach follows the research team's identification of the mechanisms of action for PD1 and IL-10, molecules known to regulate HIV persistence and immune dys

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50% of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unkn

For persons diagnosed with HIV (PWH) aged 50 years and older, progress on quality of life (QoL) goals is limited, according to a study published online Sept. 12 in Morbidity and Mortality Weekly Report.

For persons diagnosed with HIV (PWH) aged 50 years and older, progress on quality of life (QoL) goals is limited, according to a study published online Sept. 12 in Morbidity and Mortality Weekly Report.Linda Beer, Ph.D., from the U.S. Centers for Disease Control and Prevention, and colleagues examined progress toward goals for improvin

It could be a real breakthrough for people at risk for HIV infection: A shot given every six months that reduces their risk by a whopping 96%.

It could be a real breakthrough for people at risk for HIV infection: A shot given every six months that reduces their risk by a whopping 96%.That's according to new trial results released Thursday by Gilead Sciences, which is repurposing its HIV treatment, the antiviral lenacapavir, as a twice-yearly preventive shot.There's a catch, h

In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with HIV. A subset of participants also demonstrated long-term control of the virus months after antibody levels declined to low or undetectable. The findings are published in Natu

Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and eliminate it entirely in people living with HIV who receive antiretroviral therapy, Canadian researchers say in a new study.

A total of seven individuals worldwide (two patients in Berlin and patients in London, Düsseldorf, New York, City of Hope and Geneva) are considered likely to have been cured or to be in long-term remission of HIV infection after receiving a bone marrow transplant to treat blood cancer.

The Centers for Disease Control and Prevention first used the term "AIDS" on Sept. 24, 1982, more than a year after the first cases appeared in medical records. Those early years of the crisis were marked by a great deal of confusion over what caused the disease, who it affected and how it spread.

A new study has uncovered empirical evidence that shows what researchers have long suspected about HIV risk—that having multiple risk factors is much worse than having only one.

Research at Weill Cornell Medicine suggests that childhood immunization against HIV could one day provide protection before the risk of contracting this potentially fatal infection dramatically increases in adolescence.

In the late 1980s, Linda Rose Frank began working with HIV-positive individuals at the University of Pittsburgh. At the time, those affected were mainly young men with a terrifying prognosis.

It's a worrying question for health officials in one of the richest and most developed areas of the African continent: Why are babies being born with HIV when free medication is available to prevent mother-to-child transmission?

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

People with HIV can no longer be turned away if they try to enlist in the U.S. military, a federal judge has ruled.The decision, issued this week by U.S. District Judge L

People with HIV can no longer be turned away if they try to enlist in the U.S. military, a federal judge has ruled.

For years, Latinos represented the biggest share of new HIV cases in this city, but testing data suggests the tide may be turning.

Public health messaging that drives stigma around pre-exposure prophylaxis (PrEP), a medication that can reduce HIV risk by up to 99%, appears to play a role in uptake of the medication. While the potential mismarketing of the drug is well-understood and has been studied extensively, few studies have examined factors associated with the perception of stigma among PrEP users.

A study by researchers from the CUNY Institute for Implementation Science in Population Health (ISPH) at CUNY SPH, published in the journal AIDS and Behavior, found that gay and bisexual men reported a general willingness to consider a potential HIV vaccine, while expressing concerns about side effects, safety, and potential barriers.

A study published in Scientific Reports by researchers at Karolinska Institutet reveals that different antiretroviral therapies (ART) influence the gut and oral microbiome, as well as body mass index (BMI), in people living with HIV. The findings highlight the importance of considering microbiome changes when selecting ART regimens.

Ugandan women's ability to negotiate the conditions and timing of sex, such as refusing sex and asking for condom use with their partners, is key to preventing several reproductive health outcomes, say experts from the Brown School at Washington University in St. Louis.

A recently published article in Experimental Biology and Medicine titled "LM11A-31, a modulator of p75 neurotrophin receptor, suppresses HIV-1 replication and inflammatory response in macrophages" highlights the potential of a novel drug candidate, 2-amino-3-methylpentanoic acid [2-morpholin-4-yl-ethyl]-amide (LM11A-31),which is a p75 neutrotrophin receptor (p75NTR) modulator, in treating HIV in t

Promoting healthy diets for the entire family can better improve health outcomes for people with chronic illnesses, according to a new Cornell study.

A single shot of an experimental injection dramatically reduces levels of the monkey form of HIV in nonhuman primates for at least 30 weeks, according to a study published today in Science. The new research suggests that the lab-made shot has the potential to offer a simple and durable alternative to the current standard treatment for people living with HIV, which is effective but demanding.

Long-acting injectable cabotegravir (CAB-LA) appears to be well tolerated in pregnant women, according to a study presented at AIDS 2024, the 25th International AIDS Conference, held from July 22 to 26 in Munich.Sinead Delany-Moretlwe, M.B.B.Ch., Ph.D., from the University of the Witwatersrand in South Africa, and colleagues reported on materna

For patients with HIV in the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) trial, use of abacavir was associated with an increased incidence of major adverse cardiovascular events (MACE), according to a study presented at AIDS 2024, the 25th International AIDS Conference, held from July 22 to 26 in Munich.Carl J. Fichtenbaum, M.

The incidence rate of hepatitis C virus (HCV) reinfection was 4.7 per 100 person-years among men who have sex with men (MSM) with HIV who cleared HCV, according to a study published online July 18 in Clinical Infectious Diseases.Daniel S. Fierer, M.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues co

In a research letter published online July 24 in the New England Journal of Medicine, the authors describe long-acting early viral inhibition (LEVI) among patients with acute HIV infection in the context of long-acting injectable cabotegravir (CAB-LA) preexposure prophylaxis (PrEP). The research was published to coincide with the 25th Internat

MacArthur Flournoy has lived with HIV since 1988, though a nurse at the time told him that he would likely die within two years.

For adolescent girls and young women, lenacapavir every 26 weeks is beneficial for preventing acquired HIV infection, according to a study published online July 24 in the New England Journal of Medicine to coincide with the 25th International AIDS Conference, held from July 22 to 26 in Munich.Linda-Gail Bekker, M.B., Ch.B., Ph.D., from

Three people effectively cured of HIV have spoken about how a risky transplant procedure saved their lives, with one saying they are "living proof" of hope in the fight against the virus.

This study provides new perspectives on transmission of hepatitis C virus (HCV), a virus that infects the liver and can be transmitted during injection of drugs, among men who have sex with men (MSM).

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center have conducted a breakthrough proof-of-concept study, published in the journal Gene Therapy, that found an HIV-like virus particle that could cease the need for lifelong medications.

A behavioral pain self-management intervention is effective for chronic pain in people living with HIV, according to a study published online July 15 in&nbsp;JAMA Internal Medicine.Katie Fitzgerald Jones, Ph.D., from the VA Boston Healthcare System, and colleagues evaluated the efficacy of a behavioral pain self-management interventi

A behavioral pain self-management intervention is effective for chronic pain in people living with HIV, according to a study published online July 15 in JAMA Internal Medicine.

Long-acting injectable cabotegravir (CAB-LA) was safe and well-tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study among cisgender women. The analysis of outcomes from more than 300 pregnancies and infants will be presented at the 2024 International AIDS Conference (AIDS 2024) in Munich, Germany.

A single laboratory-based HIV viral load test used by U.S. clinicians who provide people with long-acting, injectable cabotegravir (CAB-LA) HIV pre-exposure prophylaxis (PrEP) did not reliably detect HIV in a multi-country study.

Nearly 40 million people were living with the HIV virus that causes AIDS last year, over 9 million weren't getting any treatment, and the result was that every minute someone died of AIDS-related causes, the U.N. said in a new report launched Monday.

Gilead could bring the AIDS pandemic towards an end if the US pharmaceutical giant opens up access to its game-changing new HIV drug, the head of UNAIDS told AFP.

Decisions political leaders take this year will be decisive whether a target to end AIDS as a public health threat by 2030 can be reached, the United Nations said Monday.

A German man has become the seventh person to apparently be cured of HIV, researchers report.The 60-year-old man, referred to as the “next Berlin Patient,” was treated with a stem cell transplant in October 2015 for acute myeloid leukemia, researchers said.He stopped taking the antiretroviral drugs needed to suppress HIV in September 2018

A 60-year-old German man is likely the seventh person to be effectively cured from HIV after receiving a stem cell transplant, doctors announced on Thursday.

Globally, around 2.6 million children and adolescents are currently living with HIV, the majority of them in Africa. These young people are much more likely to experience treatment failure than adults. Experts long assumed that testing for viral drug resistance could improve treatment in cases where treatment has failed. However, a research team led by the University of Basel, Switzerland, now sho

Now that more people with HIV in South Africa are on antiretroviral therapy (medicines to treat HIV), more are surviving long enough to face the health consequences of tobacco smoking.

An intensive, 12-week pain self-management program has been shown to reduce pain and improve mood in a large clinical trial of people with both HIV and chronic pain. The research, led by University of Pittsburgh physician-scientist Jessica Merlin, M.D., Ph.D., found participants in the Skills to Manage Pain (STOMP) program also reported more confidence in their ability to manage pain both immediat

A study published in Clinical Infectious Diseases led by Massachusetts General Hospital investigators, warns that Tennessee's new HIV prevention funding policy will lead to poorer health outcomes for its residents.

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

After an anesthesiologist may have exposed thousands of people treated at several hospitals in Oregon to hepatitis and HIV, those patients are being advised to get tested for the diseases.Two health care providers in Portland -- Providence and Legacy Health -- have been told to offer the tests as a safety precaution."We recently learned t

Baby girls are more likely to acquire HIV from their mothers during pregnancy or childbirth than infant boys, who are conversely more likely to achieve cure or remission, researchers say in a new study that sheds light on the gender differences in immune systems.

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.

It's not making major news headlines like in the '80s, but HIV remains a significant health concern. About 38 million people are living with HIV, the virus that causes AIDS, according to the World Health Organization.

Many sexually transmitted diseases are on the rise in the United States, and a nationwide poll indicates that ignorance about how they're transmitted could be fueling their spread.About a third of Americans (34%) falsely believe sexually transmitted infections (<a href="https://www.healthday.com/a-to-z-health/infectious-diseases/most-common-st

Four months after seeking asylum in the U.S., Fernando Hermida began coughing and feeling tired. He thought it was a cold. Then sores appeared in his groin and he would soak his bed with sweat. He took a test.

Just two injections a year of a new HIV drug protected young women in Africa from infection with the sexually transmitted disease, new trial results show.In announcing the findings, Gilead Sciences Inc. said its HIV medication lenacapavir demonstrated 100% efficacy as a prev

Mailed HIV-self tests (HIVSTs) can increase testing among persons who have never received testing for HIV or have not received testing in the past year, according to research published in the June 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Travis Sanchez, from Emory University

Malcolm Reid recently marked the anniversary of his HIV diagnosis on Facebook. "Diagnosed with HIV 28 years ago, AND TODAY I THRIVE," he wrote in a post in April, which garnered dozens of responses.

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

Community-based testing and treatment response to Glasgow's HIV outbreak among people who inject drugs (PWID) successfully brought the 2015 outbreak under control, modeling led by academics at the University of Bristol suggests. The study's findings, published in the Journal of Infectious Diseases (JID), indicate that approximately three times as many people would have been infected by 2020 if the

The walls of Shadrack Mashabane's hut in the rural South African town of Bushbuckridge are covered with traditional fabrics, with a small window the only source of light. What stands out among the herbs and medicines in glass bottles is a white box containing an HIV testing kit.

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Kumamoto University researchers have developed a novel viral reporter system named HIV-Tocky (Timer of Cell Kinetics and Activity). This innovative system allows for real-time visualization of HIV dynamics post-viral infection.

In clinical guidelines issued by the U.S. Centers for Disease Control and Prevention and published June 4 in the agency's Morbidity and Mortality Weekly Report, recommendations are presented for the use of doxycycline postexposure prophylaxis (doxy PEP) for preventing sexually transmitted infections (STIs) in gay, bisexual, and other men who

Although most newly diagnosed HIV patients in the United States live in cities, about 20% of new HIV infections are diagnosed in rural areas. Sexual minority males (gay, bisexual, queer and other men who have sex with men) make up the biggest proportion of new HIV cases.

HIV infections among adolescents and young adults continue to be at high levels, with Americans between the ages of 13 and 24 accounting for approximately 20% of all new HIV infections in 2019. However, uptake of a preventive regimen known as pre-exposure prophylaxis (PrEP) in this group remains low.

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals' immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs). The findings, published today in Nature Immunology, are an encouraging, incremental step in developing a preventive HIV vaccine.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Machine learning, artificial intelligence (AI) and social media are providing researchers with the opportunity to analyze valuable information about social issues in relation to health and mental health, particularly in relation to topics people may be reluctant to discuss in other settings, according to Richard Lomotey, associate professor of information technology at Penn State Beaver.

Nikolai Scherbak, docent of biology at Örebro University, has just returned to Sweden after participating in a conference in South Africa where he presented a study that increases the chances of developing a vaccine against HIV. Together with other researchers, he has genetically modified probiotic E. coli bacteria with a part of the HIV virus.

For men who have sex with men (MSM), voluntary medical male circumcision (VMMC) is associated with a reduced risk for HIV infection, according to a study published online May 28 in the Annals of Internal Medicine.Yanxiao Gao, M.D., Ph.D., from the Chinese Academy of Sciences in Shenzhen, and colleagues examined the efficacy of VMMC in p

A randomized controlled trial comprised of 247 men who have sex with men (MSM) found that voluntary medical male circumcision (VMMC) can prevent incident HIV infection. These findings suggest that MSM should be included in VMMC guidelines. The study is published in Annals of Internal Medicine.

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

Life expectancy of youth with HIV is projected to be 10.4 years less in males and 11.8 years less in females compared to individuals without HIV, a study by researchers at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health care system, has found.

HIV has proven a hard target for vaccine design. The most promising approach, germline-targeting (GT), proposes a series of immunizations: a first shot to activate inexperienced B cells—antibody-producing white blood cells—followed by a sequence of immunogens that are more and more like the HIV Envelope (Env) protein.

In an American Academy of Pediatrics clinical report published online May 20 in Pediatrics, recommendations are presented for breastfeeding among people living with and at risk for HIV.Lisa Abuogi, M.D., from the University of Colorado School of Medicine in Aurora, and colleagues examined feeding practices for infants born to people livi

People with HIV can breastfeed their babies, as long as they are taking medications that effectively suppress the virus that causes AIDS, a top U.S. pediatricians' group said Monday in a sharp policy change.

An HIV vaccine candidate developed at the Duke Human Vaccine Institute triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

The HIV variant dominant in Indonesia was introduced from Thailand over multiple events. A Kobe University study traces where it came from and how it spread from there, offering possible insights into the development of treatments against the disease.

Having social support and strong social networks is vital to the health and well-being of older adults living with HIV, according to a Rutgers Health study.

A team led by the Duke Human Vaccine Institute (DHVI) has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.

Group-based interventions have the potential to address HIV-related stigma among adolescents living with the virus, finds a recent study from researchers at the Brown School at Washington University in St. Louis and Makerere University in Uganda.

Individuals living with HIV often face significant physical and mental stress, including self-stigma, which can impede their ability to seek treatment and disclose their status.

From 1990 to 2021, there were persistent health differences between females and males, according to a study published online May 1 in The Lancet Public Health.Vedavati Patwardhan, Ph.D., from the University of California, San Diego, and colleagues compared disability-adjusted life year (DALY) rates among females and males aged older than

The artificial intelligence (AI) chatbot called ChatGPT is a powerful way for Black women to educate themselves about HIV prevention, as it provides reliable and culturally sensitive information, according to a study in The Journal of the Association of Nurses in AIDS Care.

The border crossing separating San Diego, California, from Tijuana, Mexico, is a dynamic place. When it was closed during the COVID-19 pandemic, drug tourism from San Diego to Tijuana continued. This provided a flow of people in both directions, bringing with them not only the virus that causes COVID-19 (SARS-CoV2) but also the virus that causes AIDS (HIV).

Cognitive impairment persists in children and adolescents living with HIV even in the era of antiretroviral therapy (ART), according to research published online April 23 in eClinicalMedicine.Sophia Dahmani, from Georgetown University Medical Center in Washington, D.C., and colleagues conducted a meta-analysis to evaluate the impact o

For people with HIV (PWH), semaglutide is effective for metabolic dysfunction-associated steatotic liver disease (MASLD), according to a research letter published online April 30 in the Annals of Internal Medicine.Jordan E. Lake, M.D., from UTHealth Houston, and colleagues designed a pilot study to examine the effect of semaglutide on

For people with HIV (PWH), semaglutide is effective for metabolic dysfunction-associated steatotic liver disease (MASLD), according to a research letter published online April 30 in the Annals of Internal Medicine.

A Monash University sexual health expert has warned that an unintended consequence of Australia's migration rules could compromise Australia's goal to end the HIV epidemic by 2030.

A study has compared the development of HIV reservoirs—locations in the body where the virus persists in a latent state—between patients who receive either early or late medical interventions. The findings highlight the importance of timely treatments for managing the virus.

People with opioid use disorder (OUD) are less likely to receive palliative care during the last 90 days before death, according to a study published online April 29 in CMAJ, the journal of the Canadian Medical Association.Jenny Lau, M.D., from the University Health Network in Toronto, and colleagues conducted a cohort study using heal

There was a surge in ethics literature during COVID-19 advocating for the ethical acceptability of physicians refusing to treat, according to a study published online April 24 in Clinical Infectious Diseases.Braylee Grisel, from the Duke University Medical Center in Durham, North Carolina, and colleagues analyzed 156 articles for quali

Three women who were diagnosed with HIV after getting "vampire facial" procedures at an unlicensed New Mexico medical spa are believed to be the first documented cases of people contracting the virus through a cosmetic procedure using needles, federal health officials said.

Between 2018 and the spring of 2023, a cluster of clients who had gotten 'vampire facial' microneedling skin treatments at a New Mexico spa were diagnosed with HIV, probably via poorly cleaned instruments, a new report finds.

Perinatal transmission of HIV to newborns is associated with serious cognitive deficits as children grow older, according to a detailed analysis of 35 studies conducted by Georgetown University Medical Center neuroscientists. The finding helps pinpoint the geographic regions and factors that may be important for brain development outcomes related to perinatal HIV infection: mother-to-child HIV tra

A study led by the Centre for Epidemiological Studies on STIs and AIDS of Catalonia (CEEISCAT)—a group from the Germans Trias i Pujol Research Institute (IGTP), the Fundació Lluita contra les Infeccions (FLI), and Odense University Hospital (OUH)—has revealed that people living with HIV who have experienced an episode of COVID-19 face a significant increase in the risk of cardiovascular diseases i

Researchers have found that children of women with HIV infection have an increased risk of immune abnormalities following exposure to maternal HIV viremia, immune dysfunction, and co-infections during pregnancy. The research is published in Nature Communications.

New data from an implementation program to be presented at this year's the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27–30 April) stress that the global HIV epidemic cannot be ended without keeping former prisoners and other patients engaged in care, and outlines the efforts made by HIV care clinics in Chicago to locate formerly incarcerated individuals living with HIV who drop

Asymptomatic people living with HIV (PLWH) with a low risk for cardiovascular disease have increased coronary artery vessel wall thickness (VWT), according to a study published online April 4 in Radiology: Cardiothoracic Imaging.Khaled Z. Abd-Elmoniem, Ph.D., from the National Institutes of Health in Bethesda, Maryland, and colleagues

The U.S. Food and Drug Administration has approved Dovato (dolutegravir/lamivudine) for adolescents living with HIV.The approval is for the treatment of HIV-1 infection in adolescents aged 12 years and older (weighing ≥25 kg) with no antiretroviral (ARV) treatment history or to replace the current ARV regimen in those who are virologically s

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH). The findings, taken from a large data study comprising more than 1,200 participants, are detailed in the new paper, "Immunoglobulin G N-glycan Markers of Ac

NeuroHIV refers to the effects of HIV infection on the brain or central nervous system, and to some extent, the spinal cord and peripheral nervous system. A collection of diseases, including neuropathy and dementia, neuroHIV can cause problems with memory and thinking and compromise our ability to live a normal life.

A new study has found that increased coronary vessel wall thickness is significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV. The study is published in Radiology: Cardiothoracic Imaging.

Through his office window at what was then one of Africa's few modern clinics dealing with HIV and AIDS, the man who now oversees the United States' threatened global AIDS effort used to hear the sound of taxis pulling up throughout the day.

U.S. physicians received $12.13 billion from industry from 2013 to 2022, according to a research letter published online March 28 in the Journal of the American Medical Association.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and colleagues examined the distribution of payments within and across specialties and the medica

In their research article published in Eurosurveillance, von Schreeb et al. challenge existing assumptions regarding the relationship between the use of HIV pre-exposure prophylaxis (PrEP) and the incidence of bacterial sexually transmitted infections (STI).

Mpox cases are climbing again in the United States, with the number of reported infections now twice as high as they were at this time last year, new government data shows.In response, public health experts have raised alarms about the increase and stressed that vaccination rates against the disease need to improve.“This has the potent

A new research review to be presented at a pre-congress day for this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2024) will focus on the growing prevalence of HIV in older adults, with—using England as an example—half of adults accessing care aged now 50 years and older, and around 1 in 11 aged 65 years and older. Similar trends exist in Italy and other countrie

A team from Houston Methodist Research Institute recently showed that a nanofluidic implant delivered an HIV drug that achieved more potency than other forms of drug administration (oral) and other HIV drugs.

By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic. An international team of researchers led by Eric Arts, professor at the Schulich School of Medicine & Dentistry, and Jamie Mann, senior lecturer at the University of Bristol (U.K.), has brought us another step closer to meeting this goal, by finding a

Many patients, including those with the greatest care needs, choose telemedicine even when in-person visits are available, according to a study published online March 22 in&nbsp;JAMA Network Open.Eva Chang, Ph.D., M.P.H., from Advocate Health in Milwaukee, Wisconsin, and colleagues assessed patient characteristics associated with telem

Physicians express largely negative views about the impact of private equity (PE) on the health care system, according to a research letter published online March 11 in&nbsp;JAMA Internal Medicine.Jane M. Zhu, M.D., from Oregon Health and Science University in Portland, and colleagues conducted a survey to assess physicians' views towa

Life expectancy increased to 77.5 years in 2022, while the age-adjusted rate of drug overdose deaths increased from 2002 to 2022 but did not change from 2021 to 2022, according to two March data briefs published by the National Center for Health Statistics.Kenneth D. Kochanek, from the National Center for Health Statistics in Hyattsville, Mar

A study by Allison Appleton, Mark Kuniholm and Elizabeth Vásquez in the School of Public Health's Department of Epidemiology and Biostatistics is the first to establish a connection between physical and sexual abuse and cardiovascular disease among women living with HIV. Their work is published in the journal AIDS.

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

For people with HIV (PWH) with metabolic-associated steatotic liver disease (MASLD), semaglutide is associated with absolute and relative declines in intrahepatic triglyceride (IHTG) content, according to a study presented at the annual Conference on Retroviruses and Opportunistic Infections, held from March 3 to 6 in Denver.Jordan E. Lake, M.D

Among sexual and gender-minority people who initiate preexposure prophylaxis (PrEP) for HIV, the annual rate of discontinuation is between 35 and 40 percent, according to a study published in the March issue of Health Affairs.Yan Guo, Ph.D., from the City University of New York in New York City, and colleagues examined PrEP discontin

Adverse pregnancy outcomes related to use of the dapivirine vaginal ring (DVR) or daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) during the second trimester are uncommon, according to a study presented at the annual Conference on Retroviruses and Opportunistic Infections, held from March 3 to 6 in Denver.Felix Mhlanga, M.B.C

Following a cyberattack on one of the nation's largest health insurers that's thrown health care payments into disarray and likely exposed reams of private patient data, the U.S. Department of Health and Human Services said Wednesday it has begun an investigation into the incident.In a&nbsp;<a href="https://www.hhs.gov/about/news/2024/03/13/h

Very early treatment of in utero HIV-1 can result in antiretroviral therapy (ART)-free remission for ≥48 weeks, according to a study presented at the annual Conference on Retroviruses and Opportunistic Infections, held from March 3 to 6 in Denver.Deborah Persaud, M.D., from the Johns Hopkins University School of Medicine in Baltimore, and co

Following a cyberattack on the largest health insurer in the United States last month, health care providers continue to scramble as insurance payments and prescription orders continue to be disrupted and physicians lose an estimated $100 million a day.That <a href="https://www.ama-assn.org/press-center/press-releases/cyberattack-jeopardizes

For people with HIV (PWH) and a history of suboptimal adherence to antiretroviral therapy, long-acting injectable treatment with cabotegravir and rilpivirine (LAI) is superior to oral standard of care (SOC), according to a study presented at the annual Conference on Retroviruses and Opportunistic Infections, held from March 3 to 6 in Denver.Aa

Nurse-led management can lower cardiovascular risk factors among individuals with HIV receiving antiretroviral therapy, according to a study published online March 5 in&nbsp;JAMA Network Open.Christopher T. Longenecker, M.D., from University of Washington in Seattle, and colleagues assessed whether a multicomponent nurse-led strategy c

Researchers at Weill Cornell Medicine have shown that three months of social worker follow-up support to people hospitalized with HIV in Tanzania had health benefits at low cost. The protocol shortened the time it took participants to attend an HIV clinic and to start on antiretroviral therapy after discharge.

Nurse-led management can lower cardiovascular risk factors among individuals with HIV receiving antiretroviral therapy, according to a study published online March 5 in JAMA Network Open.

Recent work from the laboratory of Elena Martinelli, Ph.D., MPH, professor of Medicine in the Division of Infectious Diseases and of Microbiology–Immunology, has discovered how inhibiting an immune cell singling pathway in a model of HIV-1 infection may promote immune responses and decrease viral persistence in conjunction with antiretroviral therapy.

Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to a presentation today at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver.

A synergistic effect is seen for multimodal strategies to improve uptake of and adherence to HIV prevention among young people at risk for acquisition, according to a study published in&nbsp;the March issue of The Lancet Digital Health.Dallas Swendeman, Ph.D., from the University of California, Los Angeles, and colleagues assessed the

Results of the third and final cohort of the DELIVER (MTN-042) Phase Ib study found no safety concerns with use of the monthly dapivirine vaginal ring beginning during the second trimester of pregnancy and up to the time of delivery, researchers reported today at the Conference on Retroviruses and Opportunistic Infections (CROI 2024) in Denver.

In the U.S., sexual and gender minority populations are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is a key prevention method, but its effectiveness relies on consistent usage. While a significant body of research has addressed PreP initiation and adherence, far less attention has been paid to the reasons for and consequences of PrEP discontinuation.

The elevated cardiovascular disease risk among people with HIV is even greater than predicted by a standard risk calculator in several groups, including Black people and cisgender women, according to analyses from a large international clinical trial presented at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver. The risk of having a first major cardiovascular event

New research definitively shows that HIV antiretrovirals can be taken together with gender-affirming hormone therapy without changing how well either drug works. The study findings can help health care providers address potential patient concerns that one drug will counteract the other.

Molecular simulations on the JUWELS supercomputer show how the HIV-1 virus is able to evade the human immune system. The newly discovered mechanism could prove to be the Achilles' heel of the virus and open new doors for HIV therapies.

In a review published online Feb. 9 in The Lancet Infectious Diseases, updated guidelines are presented for the diagnosis and management of cryptococcosis.Christina C. Chang, Ph.D., from Alfred Hospital in Melbourne, Australia, and colleagues updated guidance and implementable recommendations on the clinical approaches, screening, diag

Women in health care occupations endure a significantly higher level of stress and burnout than men, according to a study published online Feb. 21 in Global Advances in Integrative Medicine and Health.Viktoriya Karakcheyeva, M.D., from the George Washington University School of Medicine and Health Sciences in Washington, D.C., and colle

Disparities across the HIV care continuum exist for people with intellectual and developmental disabilities (IDDs), according to a study published in the February issue of the&nbsp;Journal of Intellectual Disability Research.Tyler G. James, Ph.D., from the University of Michigan in Ann Arbor, and colleagues assessed the prevalence of HI

Accelerated epigenetic aging is seen in women with HIV versus women without HIV, according to a study published online Feb. 15 in the&nbsp;Journal of Infectious Diseases.Stephanie Shiau, Ph.D., from the Rutgers School of Public Health in Piscataway, New Jersey, and colleagues examined the relationship between accelerated epigenetic ag

First Lady Jill Biden on Wednesday announced $100 million in federal funding to fuel research into women's health.“We will build a health care system that puts women and their lived experiences at its center,” Biden said in a White House <a href="https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/02/21/remarks-as-prepared-for-deliv

A recent clinical trial reveals how a daily statin pill may prevent heart attacks and strokes in people with HIV. In this substudy of the phase 3 Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), a team led by investigators at Massachusetts General Hospital (MGH) discovered that pitavastatin reduces plaque buildup in the heart's coronary arteries and lowers inflammation in the blood.

The consequences of a fall can be devastating, particularly among people who are at higher risk of a fracture such as people with HIV. Alcohol consumption and drug use are important risk factors for falls or fractures, but there are no standard medical guidelines on the level of consumption or type of alcohol or other drug use (AOD) that increases one's risk for falls and fall-related injuries, pa

Unexpected medical bills and high health care costs are dominating an election where kitchen table economic problems weigh heavily on voter’s minds, a new KFF poll has found.Voters struggling to pay their monthly bills are most eager to hear presidential candidates talk about economic and health care issues, according to the latest KFF Health

Droughts have the potential to increase the spread of HIV for women living in rural parts of Africa, researchers at the University of Bristol have found.

South Africa continues to have a high prevalence of HIV among all age groups. About 8.2 million people or 13.7% of the population live with HIV, one of the highest rates in the world.

People with disabilities are often at higher risk for exposure to HIV due to barriers in engaging health care and other systemic factors and are thus considered a priority for prevention and testing efforts. However, these efforts don't always extend to people with intellectual disabilities due to the perception that people with intellectual disabilities are mostly asexual.

Women with HIV experience accelerated DNA aging, a phenomenon that can lead to poor physical function, according to a study led by Stephanie Shiau, an assistant professor in the Department of Biostatistics and Epidemiology at the Rutgers School of Public Health.

Published in the Journal of Infectious Diseases, new research led by the University of Minnesota Medical School offers a new avenue of hope in the fight against chronic human immunodeficiency virus (HIV) infection.

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.

In December, the journal Vaccines published an analysis of COVID-19 vaccination coverage among people with HIV in Catalonia between December 2020 and July 2022. The study led by the Center for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT), a group from the Germans Trias i Pujol Research Institute (IGTP), in collaboration with researchers from the PISCIS Cohort group, evaluate

Researchers have found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HI

Researchers from Children's Hospital of Philadelphia (CHOP) and Johns Hopkins University School of Medicine studied how high levels of substance and polysubstance use are associated with sexual practices, and partner characteristics that can reinforce risk for HIV acquisition or transmission among Black and Latinx sexual youth as well as gender minority youth. The findings were recently published

Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it—inventing all sorts of tricks.

People living with HIV alongside common mental health disorders may be three times more likely to maintain a low level of virus through medication if supported with therapy through the Friendship Bench project, according to new study results.

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

Older adults have a mean of 20.7 total health care contact days per year, according to a study published online Jan. 23 in the Annals of Internal Medicine.Ishani Ganguli, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and colleagues characterized health care contact days among community-dwelling adults aged 65 years and olde

Control of dyslipidemia and diabetes, but not hypertension, reduces the association of HIV status with cardiovascular disease (CVD), according to a study published online Jan. 16 in Clinical Infectious Diseases.Michael J. Silverberg, Ph.D., M.P.H., from Kaiser Permanente Northern California in Oakland, and colleagues conducted a retrosp

Control of dyslipidemia and diabetes, but not hypertension, reduces the association of HIV status with cardiovascular disease (CVD), according to a study published online Jan. 16 in Clinical Infectious Diseases.

University of Virginia School of Medicine researchers have found long-sought answers to questions about HIV transmission, and those findings could lead to new ways to prevent the disease's spread.

Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people. The antibodies—a human broadly neutralizing antibody and two antibodies isolated from previously vaccinated monkeys—target the fusion peptide, a site on an HIV surface protein that

In women living with HIV, preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy, according to the final results of MAMAH, a clinical trial coordinated by the Barcelona Institute for Global Health (ISGlobal). The study, published in the Lancet Infectious Diseases, could help protect the health of the estimated one million pregnant women who suffer fr

With only days left before open enrollment closes, the Biden administration announced Wednesday that 20 million Americans have already signed up for health insurance under the Affordable Care Act."Today, we hit a major milestone in lowering costs and ensuring all Americans have access to quality, affordable health care. With six days left to s

In 2022, 5.7 percent of adults reported lacking reliable transportation for daily living, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.Amanda E. Ng, Ph.D., M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues u

Mayo Clinic researchers have unraveled the molecular mechanisms that affect which cells infected with human immunodeficiency virus (HIV) die and which survive, a discovery heralded as a step toward eliminating all HIV-infected cells from the body.

A new paper in Molecular Biology and Evolution finds that HIV populations in people with higher viral loads also have higher rates of viral recombination. In effect, the more HIV in the blood, the easier it is for the virus to diversify.

An increase in out-of-pocket costs for HIV preexposure prophylaxis (PrEP) medications could increase abandonment of PrEP, leading to an increase in HIV diagnoses, according to a study published in the January issue of Health Affairs.Lorraine T. Dean, Sc.D., from Johns Hopkins University in Baltimore, and colleagues estimated the risk-adj