All articles tagged: Nephrology

There are bidirectional associations for sleep disorders with chronic kidney disease (CKD), according to a review published in the November issue of Chronic Kidney Journal.Jin Hean Koh, from the National University of Singapore, and colleagues examined the bidirectional association between sleep disorders and CKD in a systematic revi

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

For patients with chronic kidney disease (CKD), the risk for emergently treated hypocalcemia with denosumab increases with worsening CKD stage, according to a study published online Nov. 19 in the Annals of Internal Medicine.Steven T. Bird, Ph.D., Pharm.D., from the U.S. Food and Drug Administration in Silver Spring, Maryland, and coll

Gabapentinoid use is associated with an increased risk for hip fractures, according to a study published online Nov. 13 in JAMA Network Open.Miriam T.Y. Leung, from the Centre for Medicine Use and Safety at Monash University in Melbourne, Australia, and colleagues investigated the association between gabapentinoids and the risk for

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

For patients with nephrolithiasis, sodium-glucose cotransporter-2 (SGLT-2) inhibitor use is associated with a reduction in recurrence, according to a study published online Oct. 30 in The BMJ.Natalie McCormick, Ph.D., from Massachusetts General Hospital in Boston, and colleagues emulated target trials comparing recurrence of nephrolith

Acute kidney injury is being redefined as a collection of syndromes, each of which could be targeted by specific biomarkers.

Boys and men aged >16 to <55 years have an increased risk for acute kidney injury (AKI) during hospitalization, according to a study published online Oct. 22 in the American Journal of Kidney Disease.Noting that female sex hormones have been suggested to play a protective role in kidney disease, Ladan Golestaneh, M.D., from the Yal

Clinical data and machine learning can help to predict intradialytic hypotension (IDH) for patients undergoing hemodialysis, according to a study published online Sept. 14 in the Journal of Kidney Care.Shamsul K. Masum, Ph.D., from the University of Portsmouth in the United Kingdom, and colleagues investigated the scope of machine lea

The annual meeting of the American Society of Nephrology (Kidney Week) was held this year from Oct. 23 to 27 in San Diego, attracting attendees from around the world, including nephrology specialists, researchers, scientists, and other health care professionals. The conference featured presentations focusing on the latest

The interaction between the gut microbiome and metabolites may mediate the effects of exposure to per- and polyfluoroalkyl substances on reduced kidney function in young adults.

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

A dietary intervention restored kidney function in animal studies and in a pilot study of patients with chronic kidney disease.

Chronic kidney disease (CKD) cases and deaths in women surged worldwide between 1990 and 2021, according to a study presented at Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to 27 in San Diego.Sree Abhilekha Purohit, M.B.B.S., from the Shadan Institute of Medical Sciences in Hyderabad, India, and collea

Lack of health insurance coverage accounts for a considerable proportion of racial and ethnic disparities in advanced-stage diagnoses of cancer, according to a study published online Oct. 30 in the Journal of the National Cancer Institute.Parichoy Pal Choudhury, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined

While some cancer treatments have a known AKI risk, exposure to GLP-1 receptor agonist drugs shows no added risk.

There are small but important differences in risk for some clinical outcomes associated with rosuvastatin and atorvastatin, according to a study published online Oct. 29 in Annals of Internal Medicine.Shiyu Zhou, M.D., from Southern Medical University in Guangzhou, China, and colleagues compared the real-world effectiveness and

Atrasentan is associated with a significant and clinically meaningful reduction in proteinuria compared with placebo in patients with immunoglobulin A (IgA) nephropathy, according to a study published online Oct. 25 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology,

Hypertension is the most common cardiovascular disease (CVD) comorbidity seen among dialysis patients globally, according to a study presented at Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to 27 in San Diego.Belen Alejos, Ph.D., from Fresenius Medical Care in Bad Homburg, Germany, and colleagues a

While targeted intervention improved hyponatremia in hospitalized patients, subsequent benefits in mortality and rehospitalization were not observed.

Many Medicare beneficiaries are at risk for financial hardship from the costs of a single hospital stay, according to a study published online Oct. 29 in the Annals of Internal Medicine.Paula Chatterjee, M.D., M.P.H., from the University of Pennsylvania Perelman School of Medicine, and colleagues identified beneficiaries who would face

Pegcetacoplan substantially reduced proteinuria in these potentially debilitating rare kidney diseases in a new phase 3 study.

Empagliflozin continues to offer cardiorenal benefits for up to 12 months after discontinuation among patients with chronic kidney disease at risk for progression, according to a study published online Oct. 25 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held fro

For children with vesicoureteral reflux, recurrent urinary tract infections (UTIs) are associated with a decrease in estimated glomerular filtration rate (eGFR), according to a research letter published online Oct. 24 in JAMA Pediatrics to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to

Patients with broad range of kidney function show reduced effects following discontinuation after EMPA-KIDNEY trial.

In a first renal outcome trial of its kind, the SGLT2 inhibitor showed favorable outcomes in the most advanced stages of CKD.

An intervention designed to better manage acute kidney injury in hospitalized patients through recommendations from a dedicated kidney action team did not meet the primary outcome.

An analysis of the FINEARTS-HF trial, which showed finerenone's benefits in heart failure outcomes, shows no significant effects on eGFR outcomes.

The U.K. Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) model, developed using advanced artificial intelligence, demonstrates superior calibration and discrimination for predicting kidney graft survival, according to a study published online Oct. 22 in Renal Failure.Hatem Ali, from University Hospitals of Coventry and W

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

⁸⁹Zr-labeled monoclonal antibody ([⁸⁹Zr]Zr-girentuximab) for positron emission tomography-computed tomography (PET-CT) is accurate for detecting patients with clear-cell renal cell carcinoma, according to a study published online in the October issue of The Lancet Oncology.Brian Shuch, M.D., from the University of California Los Angeles

Patients with comorbid diabetes have an elevated risk for lower extremity amputation (LEA) at all stages of chronic kidney disease (CKD) compared with patients without diabetes, according to a study published online in the November issue of Journal of Diabetes and Its Complications.Dhruv Nandakumar, from University of Texas Southwestern

There are no significant differences in all-cause or cardiovascular mortality with the prescription of dialysate calcium 1.50 versus 1.25 mmol/L for patients undergoing hemodialysis, according to a study published online Oct. 4 in the&nbsp;Clinical Kidney Journal.Karlien J. ter Meulen, from Maastricht University Medical Centre in the Ne

Among recipients with HIV, kidney transplantation from donors with HIV is noninferior to that from donors without HIV, according to a study published online Oct. 16 in the New England Journal of Medicine.Christine M. Durand, M.D., from Johns Hopkins University School of Medicine in Baltimore, and colleagues compared transplantation of

For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association.Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital -- Herlev a

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

For patients undergoing nonemergent cardiopulmonary bypass (CPB), use of an extracorporeal blood purification (EBP) device is associated with a lower rate of cardiac surgery-associated acute kidney injury (CSA-AKI), according to a study published online Oct. 9 in the Journal of the American Medical Association to coincide with the annual congr

The U.S. Environmental Protection Agency on Tuesday finalized a rule that will require the removal of all lead pipes from the country's water systems.“We’ve known for decades that lead exposure has serious long-term impacts for children’s health. And yet, millions of lead service lines are still delivering drinking water to homes,”&nbsp;EPA Admi

Early detection of the disease is crucial because available medications can delay or halt its progression.

U.S. racial disparities in mortality decreased from 1999 to 2015 for Black men and to 2011 for Black women, followed by stagnation or regression, according to a study published online Sept. 30 in&nbsp;JAMA Network Open.Adith S. Arun, from the Yale School of Medicine in New Haven, Connecticut, and colleagues sought to compare excess age

These findings expose a broad gap in screening for chronic kidney disease that is especially concerning now that there are effective treatments.

For patients with residual kidney stone fragments, the risk for relapse is lower with ultrasonic propulsion-facilitated clearance of fragments, and adverse events are mild, according to a study published online Aug. 14 in The Journal of Urology.Matthew D. Sorensen, M.D., from the University of Washington School of Medicine in Seattle, a

Few patients with abnormal protein dipstick results have follow-up albuminuria quantification, according to a research letter published online Oct. 1 in the Annals of Internal Medicine.Noting that guidelines recommend follow-up albumin-creatinine ratio (ACR) testing if the protein dipstick test result is abnormal, Yunwen Xu, Ph.D., fro

For patients with obesity, type 2 diabetes, and estimated glomerular filtration rate (eGFR) 20 to 60 mL/min/1.73 m2, metabolic surgery is associated with a lower risk for progression of kidney impairment compared with glucagon-like peptide-1 receptor agonist (GLP-1RA) treatment, according to a study published in the September issue of the <

For people with an eating disorder, electrolyte abnormalities are associated with death and poor physical health outcomes, according to a study published in the October issue of The Lancet Psychiatry.Marco Solmi, M.D., Ph.D., from the University of Ottawa in Ontario, Canada, and colleagues conducted a retrospective population-based co

There is a J-shaped association between systemic immune-inflammation index (SII) levels and all-cause mortality in patients with chronic kidney disease (CKD), according to a study published online Sept. 10 in&nbsp;Immunity, Inflammation and Disease.Meng Jia, from the Shanghai University of Traditional Chinese Medicine, and colleagues

Extreme temperature-related deaths are projected to increase considerably by the mid-21st century in the contiguous United States, according to a study published online Sept. 20 in JAMA Network Open.Sameed Ahmed M. Khatana, M.D., M.P.H., from the University of Pennsylvania Perelman School of Medicine in Philadelphia, and colleagues exa

Patients undergoing peritoneal dialysis (PD) have significantly higher thyroxine (T4) concentrations than hemodialysis (HD) patients and higher free T4 (FT4) concentrations at 12 and 24 months, according to a study published online Sept. 7 in Seminars in Dialysis.Jelić Pranjić Ita, M.D., from the University Hospital Center Rijeka in Cr

In a report issued by the American Society of Nephrology and published online Sept. 18 in the Journal of the American Society of Nephrology, guidance is presented for the management of obesity in persons with kidney disease.T. Alp Ikizler, M.D., from Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues developed

For patients with metastatic renal cell carcinoma (mRCC) and progression during or after one to two prior lines of therapy, including one immune checkpoint inhibitor (ICI), tivozanib has efficacy, according to a study published online Sept. 13 in The Lancet to coincide with the annual meeting of the European Society for Medical Oncology, held

For veterans with incident chronic kidney disease (CKD), a history of homelessness is associated with an increased risk for end-stage kidney disease (ESKD) and death, according to a study published online Sept. 10 in JAMA Network Open.Alain K. Koyama, Sc.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colle

A FLOW subanalysis suggested the benefits of combination, but some questioned the rationale.

Break Wave lithotripsy (BWL) is a safe and effective noninvasive stone therapy, according to a study published online Sept. 11 in The Journal of Urology.Ben H. Chew, M.D., from the University of British Columbia in Vancouver, Canada, and colleagues reported on a prospective, multicenter, single-arm clinical trial using the SonoMotio

Control of multiple risk factors "effectively nullified” the excess risk for chronic kidney disease in individuals with obesity compared with individuals of normal weight.

Empagliflozin confers kidney-protective benefits for patients with acute myocardial infarction (MI) and an increased risk for heart failure, according to a study presented at the European Society of Cardiology Congress 2024, held from Aug. 30 to Sept. 2 in London.Rahul Aggarwal, M.D., from Harvard Medical School in Boston, and colleagues conduct

Individuals with acute kidney injury (AKI) have an increased risk for receiving a clinical diagnosis of dementia, according to a study published online Aug. 22 in Neurology.Hong Xu, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined the association between experiencing AKI and subsequent risks for develo

Electronic alerts for acute kidney injury were associated with a lower risk for disease progression, increased nephrologist consultations, and reduced NSAID exposure, found an updated meta-analysis.

Impaired central sensitivity to thyroid hormone may increase the risk for mortality in patients with stages 1-4 chronic kidney disease and normal thyroid function.

More than 5 billion people globally do not consume enough iodine, vitamin E, and calcium, according to a study published online Aug. 29 in The Lancet Global Health.Simone Passarelli, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues estimated micronutrient intake using a novel approach accounting for t

Increased thiazide doses were associated with a greater decrease in urine calcium and kidney stone events over a 4-year period in adults who had kidney stones.

Perioperative mortality has decreased after living kidney donation, with 0.9 deaths per 10,000 during 2013 to 2022, according to a research letter published online Aug. 28 in the Journal of the American Medical Association.Allan B. Massie, Ph.D., from NYU Langone Health in New York City, and colleagues conducted a national registry st

For adults with kidney stones, increasing thiazide dose is associated with greater reductions in calcium, which are negatively associated with symptomatic stone events, according to a research letter published online Aug. 22 in JAMA Network Open.Ryan S. Hsi, M.D., from the Vanderbilt University Medical Center in Nashville, Tennessee,

The risk for perioperative mortality in living kidney donors has significantly reduced in the past decade, a study showed.

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

Early evidence suggests race-neutral policies are having their intended effect, helping "level the playing field" in the kidney transplant process.

Researchers found an inverse association between protein intake and mortality risk in patients with CKD.

Belzutifan, a hypoxia-inducible factor 2α (HIF-2α) inhibitor, improves progression-free survival and objective responses over everolimus among patients with advanced clear-cell renal cell carcinoma, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.Toni K. Choueiri, M.D., from the Dana-Farber Can

A study published online Aug. 21 in the Journal of the American Heart Association reveals the major contributors to heart failure risk in American Indians, highlighting the roles of age, smoking, and diabetes.Irene Martinez-Morata, M.D., M.P.H., from the Columbia University Mailman School of Public Health in New York City, and colleag

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

While concerns remain in heart transplantation, recipients of kidneys from toxoplasma antibody–positive vs toxoplasma antibody–negative donors showed no significant differences in outcomes.

Higher intake of&nbsp;total, animal, and plant protein&nbsp;is associated with lower mortality in older adults with chronic kidney disease (CKD), according to a study published online Aug. 7 in JAMA Network Open.Adrián Carballo-Casla, Ph.D., from the Karolinska Institutet and Stockholm University, and colleagues examined associations

From 2020 to 2021, life expectancy at birth declined for 39 U.S. states and increased for 11 states, according to the Aug. 21 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Elizabeth Arias, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues p

Using a new classification of steatotic liver disease (SLD) based on the presence of metabolic dysfunction and alcohol consumption, metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD) are significantly associated with the new onset of chronic kidney disease (CKD), according to a study published o

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

Survival may be longer among older people with chronic kidney failure, but those patients commonly have less time at home compared with those choosing medical management.

For older adults, starting dialysis when the estimated glomerular filtration rate (eGFR) falls below 12 mL/min/1.73 m2 results in modest gains in life expectancy, according to a study published online Aug. 20 in the Annals of Internal Medicine.Maria E. Montez-Rath, Ph.D., from the Stanford University School of Medicine in Pal

The risk for patient death associated with low nurse staffing is only partly alleviated by using temporary staff to fill shortfalls, according to a study published online Aug. 19 in&nbsp;JAMA Network Open.Peter Griffiths, R.N., Ph.D., from the University of Southampton in the United Kingdom, and colleagues explored the association betwe

For recipients of renal transplant, graft survival is similar for Toxoplasma antibody-positive donors (TPD) and Toxoplasma-negative donors, according to a study published online July 11 in Transplant International.Lavjay Butani, M.D., and Daniel Tancredi, Ph.D., from the University of California Davis Medical Center in

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with lower rates of hyperkalemia and a lower rate of renin-angiotensin system inhibitor (RASi) discontinuation compared with treatment with dipeptidyl peptidase-4 inhibitors (DPP-4is) among patients with type 2 diabetes (T2D), according to a study published online Aug. 1

For patients with type 2 diabetes, treatment with tirzepatide (a dual glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptor agonist) is associated with lower risks for all-cause mortality and adverse cardiovascular and kidney events compared with glucagon-like peptide 1 receptor agonist treatment (GLP-1 RA), according to a s

In 2023, there was a provisional total of 3,090,582 deaths in the United States, according to research published in the Aug. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Farid B. Ahmad, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

There is a complex interaction among social determinants of health with mortality risk, but a scoring system is able to identify subgroups with a high risk for mortality, according to a study published online Aug. 5 in BMJ Open.Marie-Pier Bergeron-Boucher, Ph.D., from the Interdisciplinary Centre on Population Dynamics at Syddansk Uni

Diets high in fruits and vegetables are associated with lower blood pressure, reduced cardiovascular risk, and improved kidney health, possibly due to their base-producing effects, according to a study published online Aug. 6 in The American Journal of Medicine.Nimrit Goraya, M.D., from Baylor Scott and White Health in Temple, Texas, an

Disparities in timely wait-listing among pediatric kidney transplant candidates expose some patients to greater harms from dialysis, according to a study published online Aug. 1 in&nbsp;Pediatrics.Lindsey M. Maclay, from the Columbia University Vagelos College of Physicians and Surgeons in New York City, and colleagues assessed dispari

Eye-level communication by clinicians appears beneficial compared with standing at the bedside of inpatients, according to a review published online July 17 in the&nbsp;Journal of General Internal Medicine.Nathan Houchens, M.D., from the University of Michigan Medical School in Ann Arbor, and colleagues conducted a systematic literatur

The performance of digital subtraction angiography (DSA)-guided tunneled dialysis catheters (TDC) is superior to that of ultrasound-guided TDC in renal replacement therapy, according to a study published online July 9 in Renal Failure.Yiwei Shang, from the Zhejiang Provincial People's Hospital in China, and colleagues conducted a retr

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

For patients with atrial fibrillation (AF), pulsed field ablation (PFA) demonstrates a favorable safety profile, according to a study published online July 8 in Nature Medicine.Emmanuel Ekanem, M.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues examined the safety of PFA by studying postapproval us

Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.The disease appears to be caused by malfunctions in an immune system pathway that regulates cells’ response to environmental pollutants, bacteria and toxins.Insufficient activation of this pathwa

The second person to receive a kidney from a genetically modified pig has died, surgeons at NYU Langone Health announced Tuesday.The 54-year-old patient, Lisa Pisano, had both kidney failure and heart failure. She received the pig kidney Ap

For individuals with advanced chronic kidney disease (CKD), angiotensin-converting enzyme inhibitor (ACEi) or angiotensin-receptor blocker (ARB) treatment is associated with a reduced risk for kidney failure with replacement therapy (KFRT) but not death, according to a study published online July 2 in the Annals of Internal Medicine.Elai

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study published online June 26 in JAMA Network Open.Daniel Edmonston, M.D., from the Duke University School of Medicine in Durham, North Carolina, and colleagues conducted a retrospective cohort study t

John Nicolas, a Chicago resident, has become the first person to receive a kidney transplant while awake, according to his doctors at Northwestern Medicine in Chicago.Instead of using the normal general anesthesia, doctors used a single spinal injection to anesthetize Nicolas while allowing him to remain alert."At one point during surgery

The triglyceride-glucose (TyG) index is independently associated with all-cause mortality among patients with heart failure and chronic kidney disease (CKD), according to a study published online June 12 in ESC Heart Failure.Yang Chen, from the Sun Yat-sen University in Guangzhou, China, and colleagues examined the association of the Ty

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

Among adult patients undergoing cardiac surgery, infusion of amino acids reduces the occurrence of acute kidney injury (AKI), according to a study published online June 12 in the&nbsp;New England Journal of Medicine&nbsp;to coincide with the annual Critical Care Reviews Meeting, held from June 12 to 14 in Belfast, Northern Ireland.Giov

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

In postmenopausal women, chronic kidney disease (CKD) may be associated with tooth loss, according to a study published online June 11 in&nbsp;Menopause.Na-Yeong Kim, from the Chonnam National University School of Dentistry in Gwangju, South Korea, and colleagues evaluated the association between CKD and tooth loss in postmenopausal wom

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Generation X is experiencing larger per-capita increases in the incidence of cancers than Baby Boomers, according to a study published online June 10 in JAMA Network Open.Philip S. Rosenberg, Ph.D., and Adalberto Miranda-Filho, Ph.D., from the National Cancer Institute in Bethesda, Maryland, estimated invasive cancer incidence trends

Forty-seven days after becoming the second patient to receive a new kidney from a genetically modified pig, a woman has had to have the organ removed.Lisa Pisano, 54, remains hospitalized and has been transf

Older adults with heart failure have considerable risk for kidney complications, with 6 percent progressing to dialysis at one year after hospitalization, according to a study published online May 29 in JAMA Cardiology.John W. Ostrominski, M.D., from Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues exa

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

For patients with type 2 diabetes and chronic kidney disease, semaglutide reduces the risk for clinically important kidney outcomes and death from cardiovascular causes, according to a study published online May 24 in the New England Journal of Medicine to coincide with the annual European Renal Association Congress, held from May 23 to 26 in S

Living kidney donors and nondonors have similar risks for hypertension and albuminuria, according to a study published online May 23 in the Journal of the American Medical Association.Amit X. Garg, M.D., Ph.D., from the Lawson Health Research Institute and London Health Sciences in Ontario, Canada, and colleagues examined the risk for

Initial treatment of lupus nephritis with a high glucocorticoid dose improved outcomes but resulted in increased infections and early mortality.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Once-weekly subcutaneous semaglutide shows a benefit for kidney outcomes in people with overweight or obesity and established cardiovascular disease, according to a study presented at the annual European Renal Association Congress, held from May 23 to 26 in Stockholm.Helen M. Colhoun, M.D., from the University of Edinburgh in the United Kingdom,

Using an innovative analysis technique, researchers identified antinephrin autoantibodies as markers of difficult to diagnose kidney diseases.

The effects in an obese population without diabetes and low rates of kidney disease suggest a 'potential role in the primary prevention of CKD.'

The landmark FLOW study shows the benefits extend to kidney, cardiovascular, and mortality outcomes in high-risk patients with type 2 diabetes and CKD.

Receipt of a kidney from a deceased donor who underwent dialysis is associated with an increased incidence of delayed graft function, according to a study published online May 23 in the Journal of the American Medical Association.Yumeng Wen, M.D., Ph.D., from Johns Hopkins University in Baltimore, and colleagues compared outcomes of tran

The 61st European Renal Congress to cover full gamut of nephrology news, research and practice insights.

Women receive worse primary care-based chronic kidney disease (CKD) management than men, according to a research letter published online May 16 in the Journal of the American Medical Association to coincide with the annual meeting of the Society of General Internal Medicine, held from May 15 to 18 in Boston.Jorge A. Rodriguez, M.D., from

Vitamin D deficiency is associated with increased risks for cardiovascular mortality and chronic kidney disease (CKD) progression in patients with early-stage disease, according to a study published online May 11 in&nbsp;the Journal of Endocrinological Investigation.Yanhong Lin, from Southern Medical University in Guangzhou, China, and c

Men with diabetes have a greater risk for complications than women, irrespective of diabetes duration, according to a study published online May 16 in the&nbsp;Journal of Epidemiology &amp; Community Health.Alice A. Gibson, from the University of Sydney, and colleagues investigated sex differences in incident microvascular and macrovascu

There is a negative association for oxidative balance score (OBS) with chronic kidney disease, according to a study published online April 23 in Frontiers in Nutrition.Yuyu Cao, from the Seventh Clinical Medical College at the Guangzhou University of Chinese Medicine in Shenzhen, China, and colleagues examined the association between OBS

In its biennial Cancer Disparities Progress Report published today, the American Association for Cancer Research presents the latest statistics on disparities in cancer progress experienced by ethnic-minority groups and other medically underserved populations in the United States.Robert A. Winn, M.D., from the Virginia Commonwealth Un

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Rick Slayman, the first person to receive a kidney transplant from a genetically modified pig, has died nearly two months after having the historic surgery.In a statement re

A man with end-stage renal disease who earlier this year became the first human to receive a new kidney from a genetically modified pig has died, Massachusetts General...

Cardiovascular, kidney, and metabolic (CKM) syndrome is highly prevalent in the United States, with more than 90 percent of adults meeting the criteria for stage 1 or higher, according to a research letter published online May 8 in the Journal of the American Medical Association.Rahul Aggarwal, M.D., from Harvard Medical School in Boston

For kidney transplant (KT) candidates with obesity, sleeve gastrectomy (SG) is effective, and a considerable proportion of patients undergo KT within 20.9 months, according to a study published in the May issue of the Mayo Clinic Proceedings.Aleksandra Kukla, M.D., from Mayo Clinic in Rochester, Minnesota, and colleagues conducted a retr

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

Cisplatin is lifesaving for many people with cancer, but acute kidney injury is a common and serious toxicity — can a tool identify those at risk?

From 1990 to 2021, there were persistent health differences between females and males, according to a study published online May 1 in The Lancet Public Health.Vedavati Patwardhan, Ph.D., from the University of California, San Diego, and colleagues compared disability-adjusted life year (DALY) rates among females and males aged older than

A genome-wide association study meta-analysis, published online April 26 in Nature Genetics, has identified 63 susceptibility regions containing 108 independent risk loci for kidney cancer.Mark P. Purdue, Ph.D., from the National Cancer Institute in Rockville, Maryland, and colleagues conducted a multi-ancestry genome-wide association s

Use of sodium–glucose cotransporter-2 inhibitors (SGLT2is) is associated with a substantially lower risk for dialysis and cardiovascular disease in patients with type 2 diabetes (T2D) and stage 5 chronic kidney disease (CKD), according to a study published online April 30 in the Annals of Internal Medicine.Fu-Shun Yen, M.D., from Dr. Ye

Men with chronic kidney disease show higher muscle sympathetic nerve activity, suggesting clues to their continued higher cardiovascular risk vs women even in older age.

People with opioid use disorder (OUD) are less likely to receive palliative care during the last 90 days before death, according to a study published online April 29 in CMAJ, the journal of the Canadian Medical Association.Jenny Lau, M.D., from the University Health Network in Toronto, and colleagues conducted a cohort study using heal

For patients with metastatic pheochromocytomas and paragangliomas (MPPGs), an antiangiogenic multi-tyrosine kinase inhibitor, cabozantinib, is promising, according to a study published online April 9 in The Lancet Oncology.Camilo Jimenez, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted

New Jersey native Lisa Pisano was staring down the end of her days.The 54-year-old had heart failure and end-stage kidney disease, but several chronic medical conditions excluded her as a candidate for heart and kidney transplants.“

Patients have lower hospital mortality and readmission rates when treated by female physicians, with a larger benefit observed for female patients, according to a study published online April 23 in the Annals of Internal Medicine.Atsushi Miyawaki, Ph.D., from the School of Public Health at The University of Tokyo, and colleagues conduc

For patients with end-stage kidney disease (ESKD), a high preoperative leukocyte glucose index (LGI) is associated with arteriovenous fistula (AVF) failure, according to a study published online April 1 in the Journal of Clinical Medicine.Adrian Vasile Muresan, Ph.D., from the George Emil Palade University of Medicine, Pharmacy, Scienc

For individuals with moderate-to-severe chronic kidney disease (CKD), a model, KDpredict, can accurately predict the risk for kidney failure and death, according to a study published online April 15 in The BMJ.Ping Liu, Ph.D., from the University of Calgary in Alberta, Canada, and colleagues conducted a population-based cohort study in

For patients with clear-cell renal cell carcinoma, adjuvant pembrolizumab is associated with a significant and clinically meaningful improvement in overall survival, according to a study published in the April 18 issue of the New England Journal of Medicine.Toni K. Choueiri, M.D., from the Dana-Farber Cancer Institute and Ha

Racial and ethnic segregation in residential neighborhoods and in those in which transplant centers are located were associated with decreased access to LDKT.

Bilateral Wilms tumors (BWTs) that increase in size during neoadjuvant chemotherapy, especially in younger patients, are most often stromal-predominant, according to a study published online March 27 in the Journal of the National Cancer Institute.Colton Duncan, from the Dana-Farber Cancer Institute/Boston Children's Hospital, and c

Trimethylamine N-oxide could be a novel risk factor and intervention target for chronic kidney disease.

An early rejection required treatment, but the patient in the groundbreaking case is reported to be "doing fine"; longer-term outcomes are being watched.

Three international nephrology organizations call for World Health Organization recognition of CKD as a major noncommunicable mortality driver.

For patients with the triad of chronic kidney disease, type 2 diabetes, and hypertension, the use of an electronic health record-based algorithm and intervention does not result in reduced hospitalization at one year, according to a study published in the April 4 issue of the New England Journal of Medicine.Miguel A. Vazquez, M.D., fr

Rick Slayman, the first person to receive a kidney transplant from a genetically modified pig, headed home Wednesday after faring so well that he was released from the hospital just two weeks after his groundbreaking surgery.“This moment -- leaving the hospital today with one of the cleanest bills of health I’ve had in a long time -- is one I

Biosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 in&nbsp;JAMA Health Forum.Kimberly Feng, M.D., from Brigham and Women’s Hospital in Boston, and colleagues investigated whether biosimilar competition is associa

A linear increase in the risk for chronic kidney disease progression is observed even in albuminuria ranges < 30 mg/g.

A linear increase in the risk for chronic kidney disease progression is observed even in albuminuria ranges < 30 mg/g.

For people with chronic kidney disease (CKD) and normoalbuminuria, the risk for CKD progression increases with higher levels of albuminuria, according to a study published online April 2 in the Annals of Internal Medicine.Ashish Verma, M.B., B.S., from the Boston University Chobanian &amp; Avedisian School of Medicine, and colleagues es

Following Cures Act implementation, the time for patients to access imaging results decreased, while the proportion of patients who accessed their reports before the ordering provider increased, according to a study published online March 27 in the&nbsp;American Journal of Roentgenology.Jordan R. Pollock, from the Mayo Clinic in Phoenix

U.S. physicians received $12.13 billion from industry from 2013 to 2022, according to a research letter published online March 28 in the Journal of the American Medical Association.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and colleagues examined the distribution of payments within and across specialties and the medica

For patients presenting with acute coronary syndromes (ACS) undergoing coronary angiography, inorganic nitrate treatment reduces the rate of contrast-induced nephropathy (CIN), according to a study published online March 21 in the European Heart Journal.Daniel A. Jones, M.D., Ph.D., from the Queen Mary University of London, and colle

In findings with implications for future therapies in chronic kidney disease, mouse studies show a protective effect of glucagon receptor signaling in the kidney.

A simple risk score consisting of nine covariates predicts the risk for severe cisplatin-associated acute kidney injury (CP-AKI), according to a study published online March 27 in The BMJ.Shruti Gupta, M.D., from Brigham and Women's Hospital in Boston, and colleagues developed and externally validated a prediction model for severe C

Adults with diabetes living in small towns are disproportionately impacted by complications of diabetes, according to a study published online Feb. 22 in&nbsp;Diabetes Care.Kyle Steiger, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues used the OptumLabs Data Warehouse to identify 2.9 million U.S. commercially insu

Japanese authorities on Wednesday ordered drugmaker Kobayashi Pharmaceutical to recall three dietary supplement products containing red yeast rice, or beni koji, after they...

Many patients, including those with the greatest care needs, choose telemedicine even when in-person visits are available, according to a study published online March 22 in&nbsp;JAMA Network Open.Eva Chang, Ph.D., M.P.H., from Advocate Health in Milwaukee, Wisconsin, and colleagues assessed patient characteristics associated with telem

Physicians express largely negative views about the impact of private equity (PE) on the health care system, according to a research letter published online March 11 in&nbsp;JAMA Internal Medicine.Jane M. Zhu, M.D., from Oregon Health and Science University in Portland, and colleagues conducted a survey to assess physicians' views towa

Systemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 in&nbsp;Frontiers in Immunology.Xiaoxin Liu, from Tongji Medical College at the Huazhong University of Science and Technology in Wuhan, China, and colleagues investigated the relationship between the syste

Life expectancy increased to 77.5 years in 2022, while the age-adjusted rate of drug overdose deaths increased from 2002 to 2022 but did not change from 2021 to 2022, according to two March data briefs published by the National Center for Health Statistics.Kenneth D. Kochanek, from the National Center for Health Statistics in Hyattsville, Mar

Peritoneal dialysis (PD) dropout seems not to be influenced by a history of hemodialysis (HD), according to a review published online March 5 in BMC Nephrology.Xingge Sun, from Queen's University Belfast in the United Kingdom, and colleagues conducted a systematic review and meta-analysis to explore the rate and reasons for PD dropou

For the first time ever, doctors have transplanted a genetically edited pig kidney into a human suffering from advanced kidney failure.Such pig kidneys, altered to lower the risk of rejection and disease, have been successfully placed into monkeys and brain-dead human donor bodies.But Rick Slayman, 62, is the first living patient to re

A collaborative program between bariatric and transplant teams enabled patients with morbid obesity and end-stage renal disease to become eligible for a kidney transplant.

Following a cyberattack on one of the nation's largest health insurers that's thrown health care payments into disarray and likely exposed reams of private patient data, the U.S. Department of Health and Human Services said Wednesday it has begun an investigation into the incident.In a&nbsp;<a href="https://www.hhs.gov/about/news/2024/03/13/h

Individuals with incident chronic kidney disease (CKD) stage G3 have a 14.6 percent three-year risk for rapid progression, according to a study recently published in Nephrology Dialysis Transplantation.Anne H.S. Vestergaard, M.D., Ph.D., from Aarhus University in Denmark, and colleagues conducted a nationwide, population-based cohor

Following a cyberattack on the largest health insurer in the United States last month, health care providers continue to scramble as insurance payments and prescription orders continue to be disrupted and physicians lose an estimated $100 million a day.That <a href="https://www.ama-assn.org/press-center/press-releases/cyberattack-jeopardizes

Referral of obese end-stage renal disease (ESRD) patients to metabolic and bariatric surgery (MBS) could offer a pathway to transplant, according to a study published online March 12 in the Journal of the American College of Surgery.Noting that an elevated body mass index is a major cause of transplant preclusion in ESRD, Shauna Levy,

Metabolic syndrome (MetS) score trajectories are associated with a subsequent risk for cancer, according to a study published online March 11 in Cancer.Li Deng, Ph.D., from Beijing Shijitan Hospital, and colleagues examined the relationship between MetS score trajectory patterns and new-onset cancer in a large prospective cohort study

Increased Krebs cycle metabolism in men vs pyruvate accumulation in women may underlie sex differences in diabetic kidney disease outcomes.

Health care portal use was higher during the COVID-19 pandemic, according to a study published online Feb. 29 in JAMA Network Open.Esther Yoon, Ph.D., M.P.H., from the Feinberg School of Medicine at Northwestern University in Chicago, and colleagues examined the prevalence of health care portal use before, during, and after the most re

At the county level, medical debt is associated with worse health status, premature death, and increased mortality rates, according to a study published online March 4 in JAMA Network Open.Xuesong Han, Ph.D., from the American Cancer Society in Atlanta, and colleagues conducted a cross-sectional study at the U.S. county level to examine

Contrary to initial worries, patients with COVID-19 who develop AKI aren't at higher risk for long-term renal damage than patients with other causes of kidney disease.

During the COVID-19 pandemic, cancer diagnoses were lower than expected, according to a study published online Feb. 22 in JAMA Oncology.Todd Burus, from the Markey Cancer Center at the University of Kentucky in Lexington, and colleagues conducted a population-based cross-sectional analysis of cancer incidence trends using data on cases

The exposures are associated with alterations in urinary and renal biomarkers that could reflect subclinical glomerular or tubular injury, data suggested.

The KDIGO updates addressed the "unprecedented pace" of scientific advances, including approval of avacopan as an add-on therapy.

Women in health care occupations endure a significantly higher level of stress and burnout than men, according to a study published online Feb. 21 in Global Advances in Integrative Medicine and Health.Viktoriya Karakcheyeva, M.D., from the George Washington University School of Medicine and Health Sciences in Washington, D.C., and colle