All articles tagged: Nephrology

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study published online June 26 in JAMA Network Open.Daniel Edmonston, M.D., from the Duke University School of Medicine in Durham, North Carolina, and colleagues conducted a retrospective cohort study t

John Nicolas, a Chicago resident, has become the first person to receive a kidney transplant while awake, according to his doctors at Northwestern Medicine in Chicago.Instead of using the normal general anesthesia, doctors used a single spinal injection to anesthetize Nicolas while allowing him to remain alert."At one point during surgery

The triglyceride-glucose (TyG) index is independently associated with all-cause mortality among patients with heart failure and chronic kidney disease (CKD), according to a study published online June 12 in ESC Heart Failure.Yang Chen, from the Sun Yat-sen University in Guangzhou, China, and colleagues examined the association of the Ty

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

Among adult patients undergoing cardiac surgery, infusion of amino acids reduces the occurrence of acute kidney injury (AKI), according to a study published online June 12 in the New England Journal of Medicine to coincide with the annual Critical Care Reviews Meeting, held from June 12 to 14 in Belfast, Northern Ireland.Giov

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

In postmenopausal women, chronic kidney disease (CKD) may be associated with tooth loss, according to a study published online June 11 in&nbsp;Menopause.Na-Yeong Kim, from the Chonnam National University School of Dentistry in Gwangju, South Korea, and colleagues evaluated the association between CKD and tooth loss in postmenopausal wom

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Generation X is experiencing larger per-capita increases in the incidence of cancers than Baby Boomers, according to a study published online June 10 in JAMA Network Open.Philip S. Rosenberg, Ph.D., and Adalberto Miranda-Filho, Ph.D., from the National Cancer Institute in Bethesda, Maryland, estimated invasive cancer incidence trends

Forty-seven days after becoming the second patient to receive a new kidney from a genetically modified pig, a woman has had to have the organ removed.Lisa Pisano, 54, remains hospitalized and has been transf

Older adults with heart failure have considerable risk for kidney complications, with 6 percent progressing to dialysis at one year after hospitalization, according to a study published online May 29 in JAMA Cardiology.John W. Ostrominski, M.D., from Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues exa

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

For patients with type 2 diabetes and chronic kidney disease, semaglutide reduces the risk for clinically important kidney outcomes and death from cardiovascular causes, according to a study published online May 24 in the New England Journal of Medicine to coincide with the annual European Renal Association Congress, held from May 23 to 26 in S

Living kidney donors and nondonors have similar risks for hypertension and albuminuria, according to a study published online May 23 in the Journal of the American Medical Association.Amit X. Garg, M.D., Ph.D., from the Lawson Health Research Institute and London Health Sciences in Ontario, Canada, and colleagues examined the risk for

Initial treatment of lupus nephritis with a high glucocorticoid dose improved outcomes but resulted in increased infections and early mortality.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Once-weekly subcutaneous semaglutide shows a benefit for kidney outcomes in people with overweight or obesity and established cardiovascular disease, according to a study presented at the annual European Renal Association Congress, held from May 23 to 26 in Stockholm.Helen M. Colhoun, M.D., from the University of Edinburgh in the United Kingdom,

Using an innovative analysis technique, researchers identified antinephrin autoantibodies as markers of difficult to diagnose kidney diseases.

The effects in an obese population without diabetes and low rates of kidney disease suggest a 'potential role in the primary prevention of CKD.'

The landmark FLOW study shows the benefits extend to kidney, cardiovascular, and mortality outcomes in high-risk patients with type 2 diabetes and CKD.

Receipt of a kidney from a deceased donor who underwent dialysis is associated with an increased incidence of delayed graft function, according to a study published online May 23 in the Journal of the American Medical Association.Yumeng Wen, M.D., Ph.D., from Johns Hopkins University in Baltimore, and colleagues compared outcomes of tran

The 61st European Renal Congress to cover full gamut of nephrology news, research and practice insights.

Women receive worse primary care-based chronic kidney disease (CKD) management than men, according to a research letter published online May 16 in the Journal of the American Medical Association to coincide with the annual meeting of the Society of General Internal Medicine, held from May 15 to 18 in Boston.Jorge A. Rodriguez, M.D., from

Vitamin D deficiency is associated with increased risks for cardiovascular mortality and chronic kidney disease (CKD) progression in patients with early-stage disease, according to a study published online May 11 in&nbsp;the Journal of Endocrinological Investigation.Yanhong Lin, from Southern Medical University in Guangzhou, China, and c

Men with diabetes have a greater risk for complications than women, irrespective of diabetes duration, according to a study published online May 16 in the&nbsp;Journal of Epidemiology &amp; Community Health.Alice A. Gibson, from the University of Sydney, and colleagues investigated sex differences in incident microvascular and macrovascu

There is a negative association for oxidative balance score (OBS) with chronic kidney disease, according to a study published online April 23 in Frontiers in Nutrition.Yuyu Cao, from the Seventh Clinical Medical College at the Guangzhou University of Chinese Medicine in Shenzhen, China, and colleagues examined the association between OBS

In its biennial Cancer Disparities Progress Report published today, the American Association for Cancer Research presents the latest statistics on disparities in cancer progress experienced by ethnic-minority groups and other medically underserved populations in the United States.Robert A. Winn, M.D., from the Virginia Commonwealth Un

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Rick Slayman, the first person to receive a kidney transplant from a genetically modified pig, has died nearly two months after having the historic surgery.In a statement re

A man with end-stage renal disease who earlier this year became the first human to receive a new kidney from a genetically modified pig has died, Massachusetts General...

Cardiovascular, kidney, and metabolic (CKM) syndrome is highly prevalent in the United States, with more than 90 percent of adults meeting the criteria for stage 1 or higher, according to a research letter published online May 8 in the Journal of the American Medical Association.Rahul Aggarwal, M.D., from Harvard Medical School in Boston

For kidney transplant (KT) candidates with obesity, sleeve gastrectomy (SG) is effective, and a considerable proportion of patients undergo KT within 20.9 months, according to a study published in the May issue of the Mayo Clinic Proceedings.Aleksandra Kukla, M.D., from Mayo Clinic in Rochester, Minnesota, and colleagues conducted a retr

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

Cisplatin is lifesaving for many people with cancer, but acute kidney injury is a common and serious toxicity — can a tool identify those at risk?

From 1990 to 2021, there were persistent health differences between females and males, according to a study published online May 1 in The Lancet Public Health.Vedavati Patwardhan, Ph.D., from the University of California, San Diego, and colleagues compared disability-adjusted life year (DALY) rates among females and males aged older than

A genome-wide association study meta-analysis, published online April 26 in Nature Genetics, has identified 63 susceptibility regions containing 108 independent risk loci for kidney cancer.Mark P. Purdue, Ph.D., from the National Cancer Institute in Rockville, Maryland, and colleagues conducted a multi-ancestry genome-wide association s

Use of sodium–glucose cotransporter-2 inhibitors (SGLT2is) is associated with a substantially lower risk for dialysis and cardiovascular disease in patients with type 2 diabetes (T2D) and stage 5 chronic kidney disease (CKD), according to a study published online April 30 in the Annals of Internal Medicine.Fu-Shun Yen, M.D., from Dr. Ye

Men with chronic kidney disease show higher muscle sympathetic nerve activity, suggesting clues to their continued higher cardiovascular risk vs women even in older age.

People with opioid use disorder (OUD) are less likely to receive palliative care during the last 90 days before death, according to a study published online April 29 in CMAJ, the journal of the Canadian Medical Association.Jenny Lau, M.D., from the University Health Network in Toronto, and colleagues conducted a cohort study using heal

For patients with metastatic pheochromocytomas and paragangliomas (MPPGs), an antiangiogenic multi-tyrosine kinase inhibitor, cabozantinib, is promising, according to a study published online April 9 in The Lancet Oncology.Camilo Jimenez, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted

New Jersey native Lisa Pisano was staring down the end of her days.The 54-year-old had heart failure and end-stage kidney disease, but several chronic medical conditions excluded her as a candidate for heart and kidney transplants.“

Patients have lower hospital mortality and readmission rates when treated by female physicians, with a larger benefit observed for female patients, according to a study published online April 23 in the Annals of Internal Medicine.Atsushi Miyawaki, Ph.D., from the School of Public Health at The University of Tokyo, and colleagues conduc

For patients with end-stage kidney disease (ESKD), a high preoperative leukocyte glucose index (LGI) is associated with arteriovenous fistula (AVF) failure, according to a study published online April 1 in the Journal of Clinical Medicine.Adrian Vasile Muresan, Ph.D., from the George Emil Palade University of Medicine, Pharmacy, Scienc

For individuals with moderate-to-severe chronic kidney disease (CKD), a model, KDpredict, can accurately predict the risk for kidney failure and death, according to a study published online April 15 in The BMJ.Ping Liu, Ph.D., from the University of Calgary in Alberta, Canada, and colleagues conducted a population-based cohort study in

For patients with clear-cell renal cell carcinoma, adjuvant pembrolizumab is associated with a significant and clinically meaningful improvement in overall survival, according to a study published in the April 18 issue of the New England Journal of Medicine.Toni K. Choueiri, M.D., from the Dana-Farber Cancer Institute and Ha

Racial and ethnic segregation in residential neighborhoods and in those in which transplant centers are located were associated with decreased access to LDKT.

Bilateral Wilms tumors (BWTs) that increase in size during neoadjuvant chemotherapy, especially in younger patients, are most often stromal-predominant, according to a study published online March 27 in the Journal of the National Cancer Institute.Colton Duncan, from the Dana-Farber Cancer Institute/Boston Children's Hospital, and c

Trimethylamine N-oxide could be a novel risk factor and intervention target for chronic kidney disease.

An early rejection required treatment, but the patient in the groundbreaking case is reported to be "doing fine"; longer-term outcomes are being watched.

Three international nephrology organizations call for World Health Organization recognition of CKD as a major noncommunicable mortality driver.

For patients with the triad of chronic kidney disease, type 2 diabetes, and hypertension, the use of an electronic health record-based algorithm and intervention does not result in reduced hospitalization at one year, according to a study published in the April 4 issue of the New England Journal of Medicine.Miguel A. Vazquez, M.D., fr

Rick Slayman, the first person to receive a kidney transplant from a genetically modified pig, headed home Wednesday after faring so well that he was released from the hospital just two weeks after his groundbreaking surgery.“This moment -- leaving the hospital today with one of the cleanest bills of health I’ve had in a long time -- is one I

Biosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 in&nbsp;JAMA Health Forum.Kimberly Feng, M.D., from Brigham and Women’s Hospital in Boston, and colleagues investigated whether biosimilar competition is associa

A linear increase in the risk for chronic kidney disease progression is observed even in albuminuria ranges < 30 mg/g.

A linear increase in the risk for chronic kidney disease progression is observed even in albuminuria ranges < 30 mg/g.

For people with chronic kidney disease (CKD) and normoalbuminuria, the risk for CKD progression increases with higher levels of albuminuria, according to a study published online April 2 in the Annals of Internal Medicine.Ashish Verma, M.B., B.S., from the Boston University Chobanian &amp; Avedisian School of Medicine, and colleagues es

Following Cures Act implementation, the time for patients to access imaging results decreased, while the proportion of patients who accessed their reports before the ordering provider increased, according to a study published online March 27 in the&nbsp;American Journal of Roentgenology.Jordan R. Pollock, from the Mayo Clinic in Phoenix

U.S. physicians received $12.13 billion from industry from 2013 to 2022, according to a research letter published online March 28 in the Journal of the American Medical Association.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and colleagues examined the distribution of payments within and across specialties and the medica

For patients presenting with acute coronary syndromes (ACS) undergoing coronary angiography, inorganic nitrate treatment reduces the rate of contrast-induced nephropathy (CIN), according to a study published online March 21 in the European Heart Journal.Daniel A. Jones, M.D., Ph.D., from the Queen Mary University of London, and colle

In findings with implications for future therapies in chronic kidney disease, mouse studies show a protective effect of glucagon receptor signaling in the kidney.

A simple risk score consisting of nine covariates predicts the risk for severe cisplatin-associated acute kidney injury (CP-AKI), according to a study published online March 27 in The BMJ.Shruti Gupta, M.D., from Brigham and Women's Hospital in Boston, and colleagues developed and externally validated a prediction model for severe C

Adults with diabetes living in small towns are disproportionately impacted by complications of diabetes, according to a study published online Feb. 22 in&nbsp;Diabetes Care.Kyle Steiger, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues used the OptumLabs Data Warehouse to identify 2.9 million U.S. commercially insu

Japanese authorities on Wednesday ordered drugmaker Kobayashi Pharmaceutical to recall three dietary supplement products containing red yeast rice, or beni koji, after they...

Many patients, including those with the greatest care needs, choose telemedicine even when in-person visits are available, according to a study published online March 22 in&nbsp;JAMA Network Open.Eva Chang, Ph.D., M.P.H., from Advocate Health in Milwaukee, Wisconsin, and colleagues assessed patient characteristics associated with telem

Physicians express largely negative views about the impact of private equity (PE) on the health care system, according to a research letter published online March 11 in&nbsp;JAMA Internal Medicine.Jane M. Zhu, M.D., from Oregon Health and Science University in Portland, and colleagues conducted a survey to assess physicians' views towa

Systemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 in&nbsp;Frontiers in Immunology.Xiaoxin Liu, from Tongji Medical College at the Huazhong University of Science and Technology in Wuhan, China, and colleagues investigated the relationship between the syste

Life expectancy increased to 77.5 years in 2022, while the age-adjusted rate of drug overdose deaths increased from 2002 to 2022 but did not change from 2021 to 2022, according to two March data briefs published by the National Center for Health Statistics.Kenneth D. Kochanek, from the National Center for Health Statistics in Hyattsville, Mar

Peritoneal dialysis (PD) dropout seems not to be influenced by a history of hemodialysis (HD), according to a review published online March 5 in BMC Nephrology.Xingge Sun, from Queen's University Belfast in the United Kingdom, and colleagues conducted a systematic review and meta-analysis to explore the rate and reasons for PD dropou

For the first time ever, doctors have transplanted a genetically edited pig kidney into a human suffering from advanced kidney failure.Such pig kidneys, altered to lower the risk of rejection and disease, have been successfully placed into monkeys and brain-dead human donor bodies.But Rick Slayman, 62, is the first living patient to re

A collaborative program between bariatric and transplant teams enabled patients with morbid obesity and end-stage renal disease to become eligible for a kidney transplant.

Following a cyberattack on one of the nation's largest health insurers that's thrown health care payments into disarray and likely exposed reams of private patient data, the U.S. Department of Health and Human Services said Wednesday it has begun an investigation into the incident.In a&nbsp;<a href="https://www.hhs.gov/about/news/2024/03/13/h

Individuals with incident chronic kidney disease (CKD) stage G3 have a 14.6 percent three-year risk for rapid progression, according to a study recently published in Nephrology Dialysis Transplantation.Anne H.S. Vestergaard, M.D., Ph.D., from Aarhus University in Denmark, and colleagues conducted a nationwide, population-based cohor

Following a cyberattack on the largest health insurer in the United States last month, health care providers continue to scramble as insurance payments and prescription orders continue to be disrupted and physicians lose an estimated $100 million a day.That <a href="https://www.ama-assn.org/press-center/press-releases/cyberattack-jeopardizes

Referral of obese end-stage renal disease (ESRD) patients to metabolic and bariatric surgery (MBS) could offer a pathway to transplant, according to a study published online March 12 in the Journal of the American College of Surgery.Noting that an elevated body mass index is a major cause of transplant preclusion in ESRD, Shauna Levy,

Metabolic syndrome (MetS) score trajectories are associated with a subsequent risk for cancer, according to a study published online March 11 in Cancer.Li Deng, Ph.D., from Beijing Shijitan Hospital, and colleagues examined the relationship between MetS score trajectory patterns and new-onset cancer in a large prospective cohort study

Increased Krebs cycle metabolism in men vs pyruvate accumulation in women may underlie sex differences in diabetic kidney disease outcomes.

Health care portal use was higher during the COVID-19 pandemic, according to a study published online Feb. 29 in JAMA Network Open.Esther Yoon, Ph.D., M.P.H., from the Feinberg School of Medicine at Northwestern University in Chicago, and colleagues examined the prevalence of health care portal use before, during, and after the most re

At the county level, medical debt is associated with worse health status, premature death, and increased mortality rates, according to a study published online March 4 in JAMA Network Open.Xuesong Han, Ph.D., from the American Cancer Society in Atlanta, and colleagues conducted a cross-sectional study at the U.S. county level to examine

Contrary to initial worries, patients with COVID-19 who develop AKI aren't at higher risk for long-term renal damage than patients with other causes of kidney disease.

During the COVID-19 pandemic, cancer diagnoses were lower than expected, according to a study published online Feb. 22 in JAMA Oncology.Todd Burus, from the Markey Cancer Center at the University of Kentucky in Lexington, and colleagues conducted a population-based cross-sectional analysis of cancer incidence trends using data on cases

The exposures are associated with alterations in urinary and renal biomarkers that could reflect subclinical glomerular or tubular injury, data suggested.

The KDIGO updates addressed the "unprecedented pace" of scientific advances, including approval of avacopan as an add-on therapy.

Women in health care occupations endure a significantly higher level of stress and burnout than men, according to a study published online Feb. 21 in Global Advances in Integrative Medicine and Health.Viktoriya Karakcheyeva, M.D., from the George Washington University School of Medicine and Health Sciences in Washington, D.C., and colle

Remote patient monitoring (RPM) may improve technique survival in patients on automated peritoneal dialysis (APD), according to a study published in the February issue of&nbsp;Kidney International Reports.Francisco Javier Centellas-Pérez, from Albacete General University Hospital in Spain, and colleagues evaluated the association betwee

Vifor Pharma and partner Travere Therapeutics on Friday won an endorsement for approval from the European Union's drug regulator for their drug Filspari, part of an industry...

First Lady Jill Biden on Wednesday announced $100 million in federal funding to fuel research into women's health.“We will build a health care system that puts women and their lived experiences at its center,” Biden said in a White House <a href="https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/02/21/remarks-as-prepared-for-deliv

Unexpected medical bills and high health care costs are dominating an election where kitchen table economic problems weigh heavily on voter’s minds, a new KFF poll has found.Voters struggling to pay their monthly bills are most eager to hear presidential candidates talk about economic and health care issues, according to the latest KFF Health

Fresenius Medical Care's shares fell 5% on Tuesday, despite upbeat quarterly results and higher 2024 guidance, with analysts highlighting a weak outlook for patient volumes...

The U.S. Environmental Protection Agency has introduced a tougher air quality standard that takes aim at fine particulate matter by lowering the allowable annual concentration of the deadly pollutant that each state can have."This final air quality standard will save lives and make all people healthier, especially within America's most vulnerable

For adults with type 2 diabetes, initiation of sodium-glucose cotransporter 2 inhibitors (SGLT2is) may lower the risk for nephrolithiasis, according to a study published online Jan. 29 in&nbsp;JAMA Internal Medicine.Julie M. Paik, M.D., Sc.D., M.P.H., from Brigham and Women’s Hospital in Boston, and colleagues examined the association

For adults with overweight/obesity and type 2 diabetes (T2D), longer duration of moderate-to-vigorous physical activity (MVPA) and increases in MVPA are associated with a reduced risk for progression to chronic kidney disease (CKD), according to a study published online Feb. 6 in the British Journal of Sports Medicine.Mengyi Liu, from

Prescription drug prices are nearly three times higher in the United States than in other countries, according to a report published by the RAND Corporation.Andrew W. Mulcahy, and colleagues from the RAND Corporation, compared the prices of different categories of drug products, including brand-name originator drugs, unbranded generic drugs, biol

The rate of venous thromboembolism is increased in association with cancer surgery, according to a study published online Feb. 2 in JAMA Network Open.Johan Björklund, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined the one-year risk of venous thromboembolic events after major cancer surgery in a register

During a mean follow-up of 25 years, living kidney donors have a lower rate of overall fractures compared with eligible nondonor controls, according to a study published online Jan. 24 in&nbsp;JAMA Network Open.Hilal Maradit Kremers, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues compared the overall and site-specif

Health care practitioner empathy interventions seem to improve patient satisfaction, but inadequate reporting hinders the ability to draw definitive conclusions relating to the overall effect size, according to a review published online Jan. 30 in the Annals of Internal Medicine.Leila Keshtkar, Ph.D., from the University of Leicester in

In older patients, a low estimated glomerular filtration rate (eGFR) based on creatinine and cystatin C levels (eGFRcr-cys) is more strongly associated with adverse outcomes compared with low eGFR based on creatinine level (eGFRcr), according to a study published online Jan. 30 in the Annals of Internal Medicine.Ed

Individuals with evidence of remission of type 2 diabetes have a considerably reduced risk for chronic kidney disease (CKD) and cardiovascular disease (CVD), according to a study published online Jan. 18 in Diabetologia.Edward W. Gregg, Ph.D., from the Royal College of Surgeons of Ireland in Dublin, and colleagues conducted a multicente

For female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, according to a study published online Jan. 19 in the Journal of the American Medical Association.Steven T. Bird, Ph.D., Pharm.D., from the U.S. Food and Drug

Data suggested that the use of magnetic hydrogel could be integrated into laser treatments for renal stones through ureteroscopy without immediate complications.

Older adults have a mean of 20.7 total health care contact days per year, according to a study published online Jan. 23 in the Annals of Internal Medicine.Ishani Ganguli, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and colleagues characterized health care contact days among community-dwelling adults aged 65 years and olde

Ordering palliative care consultation by default increases the rate of consultation but does not reduce the length of stay for older hospitalized patients with advanced chronic illness, according to a study published in the Jan. 16 issue of the Journal of the American Medical Association.Katherine R. Courtright, M.D., from the Perelman

New research backed up previous findings, showing a substantially higher risk for severe hypocalcemia in older patients on kidney dialysis than in those treated with oral bisphosphonates.

Reducing the frequency of salt additions to meals could contribute to lowering CKD risk in the general population, the authors speculated.

While tirzepatide has bagged FDA approval for treating T2D and for weight loss, the critical question remains — can it also safeguard the kidneys, a key objective in diabetes care?

Commercially available alkaline water is not likely to provide benefit over tap water for patients with uric acid and cystine urolithiasis, according to a study published in the February issue of The Journal of Urology.Paul Piedras, from the University of California at Irvine, and colleagues analyzed five commercially available alkal

For patients undergoing hemodialysis with chronic insomnia, the effectiveness of cognitive behavioral therapy for insomnia (CBT-I) or trazodone does not differ from placebo, according to a study published online Jan. 16 in the Annals of Internal Medicine.Rajnish Mehrotra, M.D., from the University of Washington School of Medicine in Se

A bivalent mRNA COVID-19 vaccine after receipt of an original monovalent COVID-19 vaccine is effective for preventing COVID-19-related thromboembolic events, according to research published in the Jan. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Amanda B. Payne, Ph.D., from the

With only days left before open enrollment closes, the Biden administration announced Wednesday that 20 million Americans have already signed up for health insurance under the Affordable Care Act."Today, we hit a major milestone in lowering costs and ensuring all Americans have access to quality, affordable health care. With six days left to s

In 2022, 5.7 percent of adults reported lacking reliable transportation for daily living, according to a January data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.Amanda E. Ng, Ph.D., M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues u

A new study explores if the kidney failure risk equation can identify patients with type 2 diabetes who would show renal improvement with intensive glycemic management.

Registered nurses, health technicians, and health care support workers have an increased risk for suicide compared with non-health care workers, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association.Mark Olfson, M.D., M.P.H., from Columbia University and the New York State Psychiatric

Child care stress (CCS) during the pandemic is associated with anxiety, depression, burnout, intent to reduce hours, and intent to leave among health care workers (HCWs), according to a study published online July 18 in JAMA Network Open.Elizabeth M. Harry, M.D., from the University of Colorado in Aurora, and colleagues assessed whether

Moral distress during the first nine months of the pandemic was reported by a majority of clinicians working in U.S. safety net practices, according to a study published online Aug. 25 in BMJ Open.Donald E. Pathman, M.D., M.P.H., from the University of North Carolina at Chapel Hill, and colleagues examined causes and levels of moral dis

The COVID-19 pandemic is associated with higher burnout among health care professionals (HCPs), particularly patient-facing HCPs, according to a study published online Sept. 27 in BJPsych Open.Vikas Kapil, M.B.B.S., Ph.D., from the Queen Mary University of London, and colleagues longitudinally examined mental health in 1,574 HCPs vers

Statin initiation may lower the risk for mortality and major adverse cardiovascular events (MACE) in older adults with chronic kidney disease (CKD) and no prior atherosclerotic cardiovascular disease (ASCVD), according to a study published online Dec. 6 in&nbsp;JAMA Network Open.Odeya Barayev, M.D., from Ben Gurion University of the Nege

Stress-management interventions may help individual health care workers over the short term, according to research published online May 12 in the Cochrane Database of Systematic Reviews.Sietske J. Tamminga, Ph.D., from the University of Amsterdam, and colleagues conducted a systematic review to evaluate the effectiveness of stress-red

Despite similar hospital discharge readiness scores, Black patients are less likely to be discharged with home health care (HHC) than White patients, according to a study published in the January issue of&nbsp;Medical Care.Olga Yakusheva, Ph.D., from the University of Michigan School of Nursing in Ann Arbor, and colleagues examined how

Researchers report an independent inverse link between time spent within a target body weight range and composite kidney outcomes in individuals with overweight/obesity and type 2 diabetes.

A higher self-reported frequency of adding salt to foods is associated with a higher risk for chronic kidney disease (CKD) in the general population, according to a study published online Dec. 28 in JAMA Network Open.Rui Tang, M.P.H., from Tulane University in New Orleans, and colleagues examined the association of self-reported frequ

For adults in the intensive care unit (ICU), there is a high probability that use of balanced crystalloids decreases in-hospital mortality compared with saline, according to a review published online Nov. 30 in The Lancet Respiratory Medicine.Fernando G. Zampieri, Ph.D., from HCor Research Institute in São Paulo, Brazil, and colleagu

More than half of U.S. medical interns report experiencing sexual harassment, according to a research letter published online Dec. 26 in&nbsp;JAMA Network Open.Elizabeth M. Viglianti, M.D., from the University of Michigan in Ann Arbor, and colleagues investigated possible institutional variation in experiences of sexual harassment amon

Prediabetes is highly prevalent in adult survivors of childhood cancer and is associated with future cardiovascular and kidney complications, according to a study published online Dec. 13 in the&nbsp;Journal of Clinical Oncology.Stephanie B. Dixon, M.D., M.P.H., from St. Jude Children's Research Hospital in Memphis, Tennessee, and colle

Patients with kidney stones show key alterations in gut and urinary microbiota compared with those without.

For patients with kidney failure, there appears to be no substantial improvement over time in the observed or adjusted Black-White mean living donor kidney transplant (LDKT) rate ratios (RRs), according to a study published online Dec. 15 in JAMA Network Open.Lisa M. McElroy, M.D., from Duke University School of Medicine in Durham, No

Burnout, lack of professional fulfillment, and other well-being-linked factors are associated with intention to leave (ITL) among physicians, according to a study published online Dec. 15 in JAMA Network Open.Jennifer A. Ligibel, M.D., from the Dana-Farber Cancer Institute in Boston, and colleagues describe the prevalence of burnout,

Mild and moderate kidney dysfunction are associated with left ventricular diastolic dysfunction and heart failure with preserved ejection fraction (HFpEF), according to a study published online Nov. 27 in ESC Heart Failure.Robin W.M. Vernooij, Ph.D., from Utrecht University in the Netherlands, and colleagues examined the association

The U.S. Food and Drug Administration (FDA) granted full approval to Swedish drugmaker Calliditas Therapeutics' drug to treat rare kidney disease IgA Nephropathy (IgAN), the...

Standard artificial intelligence (AI) models improve diagnostic accuracy, but systematically biased AI models reduce this accuracy, according to a study published in the Dec. 19 issue of the Journal of the American Medical Association.Sarah Jabbour, from the University of Michigan in Ann Arbor, and colleagues examined the impact of sys

Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE.Junyu Zhang, from Hunan University of Chinese Medicine in Changsha, China, and colleagues used data from European populations, including 930,014 controls and 47,309 cases of heart failure from the HERMES con

An aldosterone synthase inhibitor, BI 690517, reduces albuminuria, according to a study published online Dec. 15 in The Lancet.Katherine R. Tuttle, M.D., from the University of Washington in Seattle, and colleagues enrolled adults with an estimated glomerular filtration rate ≥30 and &lt;90 mL/min/1.73 m2, urine albumin:creati

Senior physicians treat fewer traditionally underserved patients than their junior colleagues within the same practices, according to a research letter published online Dec. 13 in&nbsp;JAMA Network Open.Hannah T. Neprash, Ph.D., from University of Minnesota School of Public Health in Minneapolis, and colleagues examined the associatio

"This update is intended to assist clinicians in the care of patients with HCV infection and CKD, including patients receiving dialysis (CKD G5D) and patients with a kidney transplant (CKD G1T-G5T)."

Increasing body mass index (BMI) at age 18 years is associated with development of subsequent site-specific cancers in men, according to a study published online Nov. 6 in&nbsp;Obesity.Aron Onerup, M.D., Ph.D., from the University of Gothenburg in Sweden, and colleagues examined BMI at age 18 years and incident site-specific cancer (

An increased risk for early CKD is observed even among adolescents with high-normal BMI and without diabetes.

The Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline on prevention, diagnosis, evaluation, and treatment of hepatitis C in chronic kidney disease has been updated, according to a report published online Dec. 12 in the Annals of Internal Medicine.Ahmed Arslan Yousuf Awan, M.D., from the Baylor College of Med

ChatGPT provided no response or incomplete or wrong answers to nearly three-quarters of drug-related questions reviewed by pharmacists, according to a study presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting, held from Dec. 3 to 7 in Anaheim, California.Sara Grossman, Pharm.D., from Long Island University in

The US National Institute of Standards and Technology has developed the first human urine standard with accurate measurements of albumin.

High body mass index (BMI) in late adolescence is associated with early chronic kidney disease (CKD) in young adulthood, according to a study published online Dec. 11 in JAMA Pediatrics.Avishai M. Tsur, M.D., from the Israel Defense Forces, Medical Corps, in Ramat Gan, and colleagues examined the association between adolescent BMI and e

Retinal optical coherence tomography (OCT) has potential to act as a noninvasive monitor and prognostic biomarker of kidney injury, according to a study published online Dec. 5 in Nature Communications.Tariq E. Farrah, B.M., B.Sc., from the University of Edinburgh in the United Kingdom, and colleagues examined the potential of retinal O

In a push for lower drug prices, the Biden administration is warning pharmaceutical companies that it might use its authority to cancel patent protections if a medication is too expensive. Federal law allows the government to grant patent licenses if taxpayer dollars were used in the development of inventions -- including drugs.In a <a href="ht

Dialysis group Fresenius Medical Care said on Wednesday that data including medical records on 500,000 patients and former patients were stolen from a US subsidiary's data warehouse.

The New Delhi city government is investigating an Apollo hospital after a media report linked it to the illegal sale by Myanmar nationals of their kidneys for organ transplants.

Minorities often feel a deep sense of dread before doctor appointments, and some even try to dress especially well for their visit to try and ward off the possibility they will face insults or unfair care. According to a new poll conducted by hea

For patients with chronic kidney disease (CKD) and type 2 diabetes, early albuminuria reduction accounts for a large proportion of the treatment effect of finerenone against CKD progression, according to a study published online Dec. 5 in the Annals of Internal Medicine.Rajiv Agarwal, M.D., from Indiana University in Indianapolis, and co

In an effort that will cost up to $30 billion over the next decade and will affect about 9 million pipes that send water to homes across the United States, the U.S. Environmental Protection Agency announced&nbsp;Thursday that it plans to require the removal of all lead pipes from the country's water systems."Lead in drinking water is a generat

From 2021 to 2022, there was an increase in life expectancy, which was seen for both sexes and across racial/ethnic groups, according to a November Vital Statistics Rapid Release report, a publication from the U.S. Centers for Disease Control and Prevention.Elizabeth Arias, Ph.D., from the National Center for Health Statistics in Hya

Two-week direct-acting antiviral (DAA) prophylaxis prevents hepatitis C virus (HCV) infection in individuals without HCV viremia who received kidney transplant (KT) from donors with HCV viremia (HCV D+/R−), according to a study published online Nov. 28 in the Annals of Internal Medicine.Niraj M. Desai, M.D., from the Johns Hopkins Univ

From 2019 to 2020, the incidence of local-stage disease decreased significantly for 19 of 22 cancer types compared with stable year-over-year changes pre-COVID-19, according to a study published online Nov. 16 in the International Journal of Cancer.Elizabeth J. Schafer, M.P.H., from the American Cancer Society in Atlanta, and colleag

For patients treated with peritoneal dialysis (PD), mean platelet volume (MPV) is associated with all-cause mortality and cardiovascular mortality, according to a study published online Nov. 8 in BMC Cardiovascular Disorders.Jianghai Wang, from the Dongying People's Hospital in China, and colleagues estimated the relationship between

The findings of the mediation analyses underscore the important role that albuminuria plays in the nephropathy and related comorbidities associated with type 2 diabetes and CKD.

For patients with lupus nephritis (LN), obinutuzumab treatment results in better preservation of kidney function and prevention of LN flares, according to a study published online Nov. 10 in Arthritis &amp; Rheumatology.Brad H. Rovin, M.D., of The Ohio State University Wexner Medical Center in Columbus, and colleagues examined whether

The two alternative formulas for calculating eGFR, the CKiD U25 and the European Kidney Function Consortium equations, showed higher levels of bias that resulted in underestimates of kidney function.

The annual meeting of the American Society of Nephrology (Kidney Week) was held this year from Nov. 2 to 5 in Philadelphia and attracted participants from around the world, including nephrology specialists, researchers, scientists, and other health care professionals. The conference featured presentations focusing on the latest adv

The Predicting Risk of Cardiovascular Disease (CVD) Events (PREVENT) risk calculator estimates the risk for CVD, including heart failure, according to a methods paper and accompanying scientific statement published online Nov. 10 in Circulation to coincide with the American Heart Association Scientific Sessions 2023, held from Nov. 11 to 13 in

For adults with early-stage chronic kidney disease (CKD), a proprietary formula performed well in stratifying risk of progression to more severe kidney dysfunction and of increased healthcare needs.

No significant differences are seen in the estimated glomerular filtration rate (eGFR) with sparsentan versus irbesartan among patients with focal segmental glomerulosclerosis (FSGS), according to a study published online Nov. 3 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of

A multicomponent intervention does not increase the rate of completed steps toward receiving a kidney transplant, according to a study published online Nov. 3 in JAMA Internal Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held from Nov. 2 to 5 in Philadelphia.Amit X. Garg, M.D., Ph.D.

Maintenance immunosuppressive drugs are associated with an increased risk for COVID-19 hospitalization in solid organ transplant recipients, according to a study published online Nov. 7 in&nbsp;JAMA Network Open.Epiphane Kolla, M.D., M.P.H., from the French National Agency for the Safety of Medicines and Health Products in Paris, and co

The findings provide support for potentially using aprocitentan in patients with BP that remains elevated despite treatment with three established antihypertensive drug classes and with stage 3 CKD.

&quot;There was an immediate and ongoing effect over a year.&quot; However, CKD screening rates in the primary care setting remain a challenge.

Advisors to the U.S. Centers for Disease Control and Prevention are expected to approve new draft guidelines for hospital infection control this week, the first update since 2007.But health care workers worry whether the guidelines, which suggest that surgical masks are as good as N-95 masks at preventing the spread of respiratory infections duri

The world's leading dialysis provider Fresenius Medical Care sees a 'balanced' impact of the GLP-1 diabetes and weight-loss drugs on its patients.

More than half of adults used the internet to look for health or medical information during July to December 2022, with higher prevalence among women than men, according to an October data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.Xun Wang and Robin A. Cohen, Ph.D., from the Na

More than half delayed or skipped care because of concerns about costs

Calculator uses readily available clinical factors and will soon be freely accessible.

Dapagliflozin became the first SGLT2 inhibitor approved for CKD alone just over 2 years ago, but uptake has lagged. Could a similar label gain for empagliflozin, plus a new recommendation, spark change?

The US Food and Drug Administration has approved Ardelyx's drug to treat high phosphate levels in patients with chronic kidney disease, the company said, more than 2 years after it was initially rejected.

Three times a week, Rachel Napaltjarri, an Aboriginal woman suffering from end-stage kidney failure, receives lifesaving dialysis in a mobile medical unit.

Novo Nordisk will stop a trial studying Ozempic to treat kidney failure in patients with diabetes ahead of schedule because it was clear from an interim analysis that the treatment would succeed.

A new study helps address a long-standing question: What's more important for our health ― physical fitness or body weight?

The US Food and Drug Administration gave the SGLT2 inhibitor empagliflozin (Jardiance) a new indication for treating adults with isolated chronic kidney disease.

Adults aged 18-39 years had a significant prevalence of subclinical kidney dysfunction that linked with a higher CVD event rate in a retrospective analysis of 8.7 million Canadian adults.