All articles tagged: Dermatology

Teledermoscopy has high accuracy for detecting skin cancers, according to a research letter published online Nov. 9 in the Journal of the American Academy of Dermatology.Jenne P. Ingrassia, from New York Medical College in Valhalla, and colleagues conducted a prospective diagnostic accuracy study to compare the accuracy of telemedici

The development marks the fifth approved indication of the drug since October 2023.

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

A study using a Korean database found that COVID-19 infection raised long-term risks for various autoimmune and autoinflammatory skin disorders, and vaccination may reduce these risks.

Dermatologic adverse events affected 97.8% of pediatric patients on MEK inhibitors, in a small retrospective single-center study.

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

Approximately 30% of patients achieved complete remission after 24 weeks.

Additional phase 3 trial results confirmed improvement in hives and itching.

Symptoms of ocular rosacea may include only “a dry, gritty feel” to the eye and a red eyelid margin, according to dermatologist Julie Harper, MD.

“There are dermatologists who don’t have much training in vulvar dermatology, and a lot of gyns don’t get as much training” as they should, said Sarah Cigna, MD.

Urea nail preparations can be used to temporarily soften the nail.

Building emotional resilience can help mitigate emotional responses.

The burden of superficial cutaneous fungal infections (SCFIs) among outpatient visits in the United States is high and increasing, according to a study published online Oct. 30 in the Journal of the American Academy of Dermatology.Sarah L. Spaulding, from the Yale School of Medicine in New Haven, Connecticut, and colleagues characterize

The European Medicines Agency has refused marketing authorizations for an herbal medicine intended to treat alopecia areata and a hybrid drug for neuroblastoma in children.

The drawbacks of retinoids involve the potential for irritancy, which can be concentration- and vehicle-dependent.

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

SDPA advocacy efforts include expansion of federal workers' comp policies to include coverage of care performed by PAs.

The odds of eczema are increased with greater exposure to fine particulate matter of diameter ≤2.5 μm (PM2.5), according to a study published online Nov. 13 in PLOS ONE.Gloria F. Chen, from the Yale School of Medicine in New Haven, Connecticut, and colleagues examined the risk for eczema with PM2.5 exposure in a

A case series characterized wounds associated with xylazine exposure, an increasingly common adulterant found in illicitly manufactured fentanyl in the United States.

The U.S. Food and Drug Administration has approved Emrosi (minocycline hydrochloride) for the treatment of inflammatory rosacea in adults.The extended-release capsules (40 mg) will be available late in the first quarter or early in the second quarter of 2025.The approval was based on positive results from two 16-week phase 3 clinical tri

Topical human platelet extract (HPE) performs as well as topical vitamin C for skin rejuvenation of dorsal hands, according to a study published in the November issue of Plastic and Reconstructive Surgery.Saranya Wyles, M.D., Ph.D., from THE Mayo Clinic in Rochester, Minnesota, and colleagues conducted a prospective, longitudinal study

Low-dose oral minoxidil did not have a significant effect on blood pressure in patients being treated for alopecia, although it increased heart rate slightly, according to a systematic review and meta-analysis.

COVID-19 infection increased the risk for autoimmune blistering diseases, but vaccination had protective effects, according to the results of a retrospective cohort study.

COVID-19 is associated with long-term risk for autoimmune and autoinflammatory connective tissue disorders, according to a study published online Nov. 6 in JAMA Dermatology.Yeon-Woo Heo, M.D., from the Yonsei University Wonju College of Medicine in South Korea, and colleagues conducted a retrospective cohort study to examine the long-ter

In addition to its effect on reducing Demodex in patients with rosacea, topical ivermectin may improve symptoms by changing the skin microbiome.

Among 355 patients with HS included in the systematic review, about 22% had inflammatory eye disease.

There is a negative association between travel time to tanning facilities and county-level melanoma incidence rates, according to a study published online Nov. 7 in the Journal of Investigative Dermatology.Guixing Wei, Ph.D., from Brown University in Providence, Rhode Island, and colleagues examined the association between melanoma inc

From 1987 to 2016, there was a considerable increase in the incidence of cutaneous malignant melanoma (CMM) among the elderly in the United States, according to a study published online Oct. 28 in Cancer Screening and Prevention.Ruofei Du, Ph.D., from Shaanxi University of Chinese Medicine in Xianyang, and colleagues examined CMM incid

Levonorgestrel IUDs were associated with increased risks for acne, alopecia, and hirsutism in a study of FDA adverse event reports.

Patients with cancer receiving immune checkpoint inhibitors had a twofold higher risk of developing psoriasis than those receiving chemotherapy or targeted therapy, according to the results of a cohort study.

A 12-year study reported over 72 million patient visits for superficial cutaneous fungal infections in the United States.

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

A new set of skin cancer risk factors can improve detection of suspicious skin lesions, according to a study published online Sept. 6 in Scientific Reports.Shafiqul Islam, Ph.D., from the University of Essex in Colchester, England, and colleagues examined artificial intelligence (AI) models that use patient metadata consisting of 23 attr

Journey Medical said on Monday the U.S. Food and Drug Administration has approved its drug for the treatment of a long-term skin condition called rosacea, sending the...

Patients with moderate to severe HS experienced sustained symptomatic and quality-of-life improvements with the monoclonal antibody bimekizumab, reveals 2-year trial data.

Actions that clinicians took for patients who screened positive for depression included providing mental health resources and referrals for therapy.

According to the study’s lead author, the topic has not been explored previously.

Lack of health insurance coverage accounts for a considerable proportion of racial and ethnic disparities in advanced-stage diagnoses of cancer, according to a study published online Oct. 30 in the Journal of the National Cancer Institute.Parichoy Pal Choudhury, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined

Surveillance data showed numbers "well above" the 5-year average, even ahead of the winter peak.

Between 2011 and 2023, the FDA reported 334 voluntary recalls of cosmetic dermatology products, mostly because of microbial contamination, according to an analysis of an FDA database.

Doctors in New York City are chronicling the first known U.S. cases of sexually transmitted ringworm (Trichophyton mentagrophytes).Until now, transmission of the fungal infection through skin-to-skin sexual contact has been rare, although cases have been reported in Southeast Asia and France since 2021, researchers reported. These hav

In a phase 2 trial, iberdomide was associated with improved symptoms when added to standard lupus medications in patients with subacute and chronic cutaneous lupus erythematosus

There seems to be a significant association between hypothyroidism, Hashimoto thyroiditis, subacute thyroiditis, and alopecia areata (AA), according to a study published in the October issue of Skin Research & Technology.Yue Zhao, from Heping Hospital Affiliated to Changzhi Medical College in China, and colleagues examined the po

Results were based on a study comparing 14,301 veterans with 209,936 nonveterans.

Researchers used the Vancouver Scar Scale (VSS) to assess treatment efficacy in 22 patients.

An analysis of three phase 3 trials reported relief with upadacitinib through 76 weeks in adolescents with AD.

Long-term treatment of adolescents with moderate-to-severe atopic dermatitis (AD) with upadacitinib is safe and effective through 76 weeks, according to a study published online Oct. 23 in JAMA Dermatology.Amy S. Paller, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues evaluated the effi

The elusive but correct diagnosis proved to be a simple, easily treated condition.

This marks the product’s fourth approved indication.

For adults with hereditary angioedema, the in vivo gene-editing therapy NTLA-2002, which is based on clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9, administered as a single dose reduces angioedema attacks, according to a study published online Oct. 24 in the New England Journal of Medicine to

“Trichophyton indotineae is changing the way we talk about dermatophyte infections,” said NYU dermatologist Avrom S. Caplan, MD.

“Gender-affirming care happens not only with medications but with communication, curiosity, and respect,” Boos said.

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

The new codes — L66.81 for CCCA and L66.12 for FFA — were implemented on October 1, 2024.

Up to 100% of ritlecitinib responders sustained hair regrowth and 30% of nonresponders achieved results at week 48 with continuous treatment, according to a post hoc study analysis.

“The degree of improvement was impressive and not far off from those reported with CO2 ablative laser,” Luke Horton, MD, said.

An interim analysis from a long-term open-label extension study has underlined the clinical efficacy and safety of nemolizumab in patients with moderate to severe AD.

A study of ruxolitinib cream in patients with lichen planus indicated that the topical JAK inhibitor is a promising potential treatment for cutaneous lichen planus that is also well tolerated.

Results of a retrospective real-world study suggested no greater risk for major CV adverse events in patients treated with upadacitinib and abrocitinib for atopic dermatitis.

Mothers with HS and their children face higher risks for adverse outcomes at birth and long-term, a study found.

A new serum containing 2-mercaptonicotinoyl glycine as its main ingredient was at least as good as cysteamine 5% cream in treating facial melasma in a randomized study.

Effective treatment with dupilumab may allow younger children with severe atopic dermatitis and short stature to catch up on their growth, potentially offering lifelong benefits, according to the results of a study of children aged 6-11 years.

HS is associated with a genetic predisposition that may increase the risk for CAD and diabetes, driven by shared genetic factors and altered plasma proteomic profiles.

A meta-analysis of 14 studies found that serum levels of anti-BP180 autoantibody strongly correlated with the severity of bullous pemphigoid.

White patients have the highest incidence of second primary melanoma, while Black patients face the greatest relative risk, according to a study.

Sensitive skin (SS) seems to be associated with primary hyperhidrosis (PHH), according to a study published online Sept. 30 in the Journal of Drugs in Dermatology.Erika T. McCormick, from the George Washington University School of Medicine and Health Sciences in Washington, D.C., and colleagues surveyed 637 PHH sufferers to assess HH a

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

Potential benzene exposure occurs as a result of benzoyl peroxide (BPO) drug product use, according to a study published online Oct. 7 in the Journal of Investigative Dermatology.The carcinogen benzene is a degradation product of BPO and has been reported to form when BPO drug products are incubated at body temperature and elevated temp

Alitretinoin netted a greater reduction in severity by 12 weeks, although differences were not significant thereafter.

Of 111 products tested, 34% contained benzene levels above the FDA limit of 2 ppm.

In a real-world study of PDL therapy in 15 adult women with recalcitrant acne, inflammatory and noninflammatory lesion counts were significantly reduced 3 months after treatment.

Epidermal necrolysis was associated with high rates of inhospital and post-discharge mortality in a French cohort study.

"Its usage could decrease needless dermatology referrals and reduce patient concerns for malignancy," the study authors wrote.

Patients with a first melanoma diagnosis have an increased risk for a second melanoma diagnosis, regardless of race and ethnicity, according to a research letter published online Oct. 9 in JAMA Dermatology.Shoshana Zhang, from Dell Medical School at the University of Texas at Austin, and colleagues examined the absolute risk of second

Interleukin-17 inhibitors showed a higher relative risk for GI events, in a review.

In a major potential step toward personalized therapy for atopic dermatitis, data suggest early, late, and no clinical response to dupilumab can be differentiated on a molecular basis.

Dermatology experts have created key recommendations to guide the standardized use of methotrexate for refractory atopic dermatitis.

The investigational IL-17A inhibitor izokibep was found to induce clear clinical responses in people with moderate to severe HS within a few weeks of treatment.

Topical delgocitinib appears more effective than oral alitretinoin and is comparable to dupilumab for treating types of hand eczema, according to two separate studies.

For patients with hidradenitis suppurativa (HS), bimekizumab is safe and efficacious over two years, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Christos C. Zouboulis, from the European Hidradenitis Suppurativa Foundation in Dessau, Germany, and

Two years after the first therapy for prurigo nodularis was approved, an oral drug in clinical trials provides a third mechanism of action for treating this disease.

Two different doses of crisugabalin resulted in significantly greater pain reductions in adults with postherpetic neuralgia than placebo in a phase 3 trial.

Eczematous dermatitis was the most common skin condition diagnosed in patients with Down syndrome, according to a multicenter retrospective review.

For patients with moderate-to-severe atopic dermatitis (AD), lebrikizumab has long-term efficacy, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Diamant Thaçi, Ph.D., from University Lübeck in Germany, and colleagues reported long-term efficacy and

Topical/skin directed therapies are best for early-stage disease or in combination with systemic therapies in advanced disease, according to Dr Arron Mangold.

By blocking IL-22 in keratinocytes, temtokibart normalizes the skin barrier and boosts hydration, suggested a study of gene expression changes in the skin.

Ruxolitinib cream applied on an as-needed basis provided sustained clearance of hidradenitis suppurativa nodules during the open-label extension of a phase 2 trial.

Most of the cancers were detected using standard age- and sex-based cancer screenings, suggesting the potential for overscreening in this population.

Home-based phototherapy for plaque and guttate psoriasis is as effective as office-based phototherapy, results of the randomized Light Treatment Effectiveness study found.

Female physicians remain underrepresented among residents entering high-compensation specialties, according to a research letter published online Sept. 30 in the&nbsp;Journal of the American Medical Association.Karina Pereira-Lima, Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined national trends in the prop

Circulating antibodies against cancer-testis antigens (CTAgs) are found in stage I and stage II melanoma plasma samples, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Cristina Vico-Alonso, M.D., from Monash University Public Health and Preventi

Improvements in the Dermatology Life Quality Index score and hidradenitis suppurativa flares were seen in people who achieved semaglutide-induced weight loss.

In a small randomized, controlled trial of patients with FFA with an open-label extension at 12 weeks, symptoms of moderate to severe frontal fibrosing alopecia improved with topical delgocitinib.

Patients with chronic spontaneous urticaria improved early, with benefits lasting through the 52-week follow-up for those who remained in the phase 2 trial.

Delgocitinib is also under FDA review for the same indication in the United States.

For plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 in JAMA Dermatology to coincide with the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Joel M. Gelf

In a 3-year extension of the pivotal trials that provided lebrikizumab with an indication for atopic dermatitis, the response at 12 months remained about the same at 3 years.

Factors that influence the skin microbiome include genetics, climate, pollution, and hygiene practices, as well as age.

When childhood atopic dermatitis persists into adulthood, the large reduction in quality of life suggests that the price of inadequate control in children is high.

Significant differences are seen in antimicrobial susceptibility between high-income and middle-income countries.

Patients with primary thyroid cancer who receive radioactive iodine therapy have an elevated risk for melanoma and other nonkeratinocyte skin cancers when limiting the cancer site to the head and neck, according to a study published online Sept. 19 in JAMA Network Open.Shawheen J. Rezaei, from the Stanford University School of Medici

For patients with obesity, the addition of semaglutide to standard hidradenitis suppurativa (HS) treatments yields improvement in quality of life and a reduction in flares, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Daniel Lyons, M.D., fro

Delayed diagnosis and treatment of CCCA result in insufficiently aggressive therapy and risks an avoidable consequence, irreversible hair loss.

For patients with advanced melanoma, there is a survival benefit for nivolumab plus ipilimumab and for nivolumab monotherapy compared with ipilimumab monotherapy, according to a study published online Sept. 15 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from S

Treatment with roflumilast cream 0.15% once daily improved mild to moderate AD in two phase 3 randomized clinical trials of children 6 years or older and adults.

The risks, appearance, and consequences for drug-induced rashes often differ in patients with skin of color, further complicating an already challenging diagnosis.

The U.S. Food and Drug Administration has approved Ebglyss (lebrikizumab-lbkz) for adults and children aged 12 years and older with moderate-to-severe atopic dermatitis.The targeted interleukin-13 inhibitor is administered via a 250-mg/2 mL injection with or without topical corticosteroids in patients with atopic dermatitis not well controll

The prevalence of precocious puberty was higher among children with hidradenitis suppurativa in a case-control study.

Now that there is an approved therapy for seborrheic dermatitis, it is time to give this condition the attention and respect it deserves across races and ethnicities.

Expected sometime in 2025, details on plans for enrollment by race, ethnicity, age, and sex will be required for all pivotal and phase 3 trials, according to a new FDA initiative.

Blood serum levels of CCL17/TARC and IL-31 and transepidermal water loss were predictive markers for atopic dermatitis in a prospective observational study of newborns.

Melanoma rates differ for men and women, including in terms of ages of occurrence and locations of melanoma, according to a study published online June 17 in the Journal of Investigative Dermatology.Catherine M. Olsen, Ph.D., from the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and colleagues analyzed long-term m

About 42% of pediatric patients with HS had obesity, in a scoping review of 12 studies.

The current pipeline includes 49 topical and 39 injectable medicines.

More than 1000 people age 12 years and older were enrolled in pivotal trials of the IL-13 inhibitor.

In a primary care population, the annual incidence of progression was low during the first few years of follow-up.

A study developed a patient-centered definition of atopic dermatitis through consensus.

"These models are not appropriate to use for patient care," Roxana Daneshjou, MD, PhD, said.

The most frequently reported adverse events in children on a JAK inhibitor were blood and lymphatic system disorders, in a review of FDA and Canadian adverse event reports.

Nailfold capillaroscopy may serve as a quick, cost-effective, and noninvasive tool to aid in the diagnosis and management of nail disorders.

For adults aged 30 to 49 years, there has been a decline in melanoma incidence and mortality, according to a study published online Sept. 8 in JAMA Dermatology to coincide with the annual meeting of the European Society for Medical Oncology, held from Sept. 13 to 17 in Barcelona, Spain.Hildur Helgadottir, M.D., Ph.D., from the Karolin

In young children, skin care product (SCP) use is associated with urinary phthalate/replacement metabolites, according to a study published online Sept. 4 in Environmental Health Perspectives.Michael S. Bloom, Ph.D., from George Mason University in Fairfax, Virginia, and colleagues examined the associations between SCP use and children'

A common food dye turned mice see-through, a "stunning" finding that could revolutionize imaging techniques in medicine.

It can take up to 1 year to see a significant response with topical immunosuppressants and narrowband ultraviolet B treatment.

Low-dose oral metformin was associated with symptomatic improvement, hair regrowth, and gene expression modulation in a case series of patients with treatment-refractory central centrifugal cicatricial alopecia.

The risk for any skin cancer was higher among US veterans than among nonveterans, according to a cross-sectional study using nationally representative data collected over 20 years.

Both nonsteroidal options are fast-acting, Jashin J. Wu said.

The association of prenatal ω-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) with the risk for childhood atopic dermatitis (AD) varies based on the maternal cyclooxygenase-1 (COX1) genotype, according to a study published online Aug. 28 in JAMA Dermatology.Liang Chen, from Herlev and Gentofte Hospital in Copenhagen, Denmark, an

Nearly 80% of patients with uveal melanoma treated with tebentafusp experienced skin reactions in a small cohort study.

Several case reports about the use of topical timolol for PG have been published in the medical literature, including a case series.

More than 5 billion people globally do not consume enough iodine, vitamin E, and calcium, according to a study published online Aug. 29 in The Lancet Global Health.Simone Passarelli, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues estimated micronutrient intake using a novel approach accounting for t

This study "provides the largest longitudinal profile" of keratinocyte carcinomas in childhood cancer survivors to date, according to the authors.

The mother's COX1 genotype could influence whether prenatal fish oil supplementation affects the risk for atopic dermatitis in children, a study found.

A study found a significantly higher risk for several psychiatric disorders in Black children with vitiligo.

Dietary intake of vitamin E may potentially lower the risk for atopic dermatitis, according to a study published online Aug. 9 in&nbsp;Skin Research &amp; Technology.Siqing Wang, from the Beijing University of Chinese Medicine, and colleagues conducted a Mendelian randomization analysis to explore the causal relationship between dietary

A crowdsourced registry study found associations between features of cutaneous neurofibromas and quality of life in patients with neurofibromatosis type 1.

The protocol included three laser treatments spaced 3-4 weeks apart combined with medical therapy and other energy-based devices.

People with self-identified xylazine wounds are more likely to engage in subcutaneous injection and face several barriers to seeking medical wound treatment, according to a study published online Aug. 21 in&nbsp;Drug and Alcohol Dependence.Raagini Jawa, from the University of Pittsburgh School of Medicine, and colleagues sought to und

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

Early childhood obesity may increase the risk for pediatric immune-mediated skin diseases, according to a study published online Aug. 21 in the&nbsp;Journal of Investigative Dermatology.Seong Rae Kim, M.D., from the Seoul National University College of Medicine in South Korea, and colleagues examined associations between body mass inde

The timeline for when an improved program might be in place remains unclear.

Zasocitinib showed significant efficacy in treating moderate to severe psoriasis, with 67%-68% of patients on higher doses achieving a PASI 75 score at 12 weeks.

Smoking cessation reduced the risk for hidradenitis suppurativa, eventually aligning with the risk for never smokers.

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

A beverage containing collagen peptides (CP), including tripeptides and elastin peptides (EP), is beneficial for the skin health of young and middle-aged women, according to a study published in the June issue of the Journal of Dermatologic Science and Cosmetic Technology.Shan Lu, from the Shenzhen Porshealth Bioengineering Co. in Ch

A seminal study from 2017 laid the groundwork for current approaches, Elizabeth Tanzi, MD, said.

Deciding which platforms to use and what voice or tone to adopt requires some soul-searching, according to Jessica G. Labadie, MD.

The top two procedures performed by the surveyed MedSpas are facials and hair removal.

Patients with skin of color may experience more adverse events from sclerotherapy, according to a study published online July 26 in the&nbsp;Journal of the American Academy of Dermatology.Michelle Lazar, from the Boston University School of Medicine, and colleagues characterized the incidence of common adverse events following sclerothe

The recommended treatment for patients with scleroderma was to use nerve blocks for injecting HA filler or hyaluronidase and to minimize the injection points.

The U.S. Food and Drug Administration has approved Nemluvio (nemolizumab) for adult patients living with prurigo nodularis.Nemluvio, administered as a prefilled pen for subcutaneous injection, inhibits interleukin-31 cytokine signaling, which is known to drive itch and is involved in inflammation, altered epidermal differentiation, and fibrosi

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

A study identified distinct clinical features and other differences in Hispanic patients with dermatomyositis compared with non-Hispanic patients.

Continuous treatment with baricitinib is needed to maintain hair regrowth in patients with severe alopecia areata.

The interleukin-31 inhibitor is also under FDA review for treating atopic dermatitis.

Cutaneous immune-related adverse events (cirAEs) are the most frequently reported and most visible adverse effects of checkpoint inhibition.

For patients with atopic dermatitis (AD), dupilumab maintains its clinical effectiveness up to five years and is discontinued by 23.8 percent of patients, according to a study published online Aug. 7 in JAMA Dermatology.Celeste M. Boesjes, M.D., from the University Medical Center Utrecht in the Netherlands, and colleagues examined clini

A gene expression signature in peripheral CD4+ T-cells can predict severe immune-related adverse events (irAEs) among melanoma patients treated with ipilimumab/nivolumab, according to a study published online Aug. 8 in Clinical Cancer Research.Kelsey R. Monson, Ph.D., from the Perlmutter Cancer Center at NYU Langone Health in

Sulfonamide antibiotics and cephalosporins are most strongly associated with serious cutaneous adverse drug reactions (cADRs), according to a study published online Aug. 8 in the Journal of the American Medical Association.Erika Y. Lee, M.D., from the University of Toronto, and colleagues explored the risk for serious cADRs associated w

There are racial differences in the frequency of skin biopsy for psoriasis, indicating diagnostic uncertainty, according to a research letter published online Aug. 7 in JAMA Dermatology.Fahad Ahmed, from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and colleagues conducted a cross-sectional study inv

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

U.S. doctors should be on the lookout for a more severe strain of mpox that is spreading widely in parts of Africa, federal health officials warned Wednesday.The&nbsp;alert,&nbsp;issued by the U.S. Centers for Disease Control and Prevention, came just hours after the World Health Org

Patients with alopecia areata (AA) have a higher prevalence of autoimmune and psychiatric comorbidities at time of diagnosis as well as a higher risk for new-onset autoimmune and psychiatric comorbidities after diagnosis, according to a study published online July 31 in&nbsp;JAMA Dermatology.Arash Mostaghimi, M.D., M.P.H., from Brigham

The U.S. Food and Drug Administration has approved Leqselvi (deuruxolitinib) tablets for the treatment of adults with severe alopecia areata.Leqselvi (8 mg) is a twice-daily oral selective inhibitor of the Janus kinases JAK1 and JAK2. In trials, the three most common adverse events were headache, acne, and nasopharyngitis.The approval was

The U.S. Food and Drug Administration is warning that chemical peels should not be used without the supervision of a dermatologist or other trained professional."FDA is warning consumers not to purchase or use certain chemical peel skin products without appropriate professional supervision due to risk of serious skin injuries," the agency said

Nonfinancial access barriers to care represent a persistent problem in the United States, with more than 12 percent of adults reporting being too busy to go to a provider, according to a study published online Aug. 1 in the&nbsp;National Health Statistics Reports, a publication from the National Center for Health Statistics.Amanda E. N

A relatively high proportion of dermatologists experience emergency complications during dermatological, surgical, or cosmetic procedures, according to a study published online July 20 in the Journal of Cosmetic Dermatology.Hilal Kaya Erdogan, M.D., from Eskişehir Osmangazi University in Turkey, and colleagues conducted a cross-section

Generation Z (Gen Z) patients present with a higher subjective perception of atopic dermatitis severity than millennial generation patients, according to a study published online July 25 in the&nbsp;International Journal of Dermatology.Clara Ureña-Paniego, from the University of Granada in Spain, and colleagues compared the clinical se

Most women with atopic dermatitis have impairment in sexual function, and about half consider that atopic dermatitis may influence their reproductive desire, according to a study published online June 11 in Acta Dermato-Venereologica.Juan-Angel Rodriguez-Pozo, from the Virgen de las Nieves University Hospital in Granada, Spain, and coll

Psoriasis and psoriatic arthritis may be associated with an increased risk of polyneuropathy, according to a study published online June 28 in&nbsp;Muscle &amp; Nerve.Pietro E. Doneddu, M.D., from the IRCCS Humanitas Research Hospital in Milan, and colleagues evaluated the risk and features of peripheral neuropathy in patients with psor

Hydroxychloroquine appears to be a safe and effective treatment option for anogenital lichen sclerosus that only has mild adverse effects, according to a study published online July 19 in the&nbsp;International Journal of Dermatology.Christeebella O. Akpala, from the Mayo Clinic in Rochester, Minnesota, and colleagues analyzed the demog

Use of oral corticosteroids for &gt;90 days during one year is associated with a slightly increased risk of adverse events (AEs), according to a study published online July 19 in&nbsp;JAMA Network Open.Yong Hyun Jang, M.D., Ph.D., from Kyungpook National University in Daegu, South Korea, and colleagues examined the association betwee

With respect to their lifetime prevalence of skin cancer, sexual minority (SM) adults differ across racial and ethnic groups and among males and females, according to a study published online July 17 in JAMA Dermatology.Katelyn J. Rypka, from the University of Minnesota in Minneapolis, and colleagues examined differences in the lifetime

To achieve maximal paralysis, patients injected with glabellar botulinum toxin may have significantly higher dose requirements in a high sun-exposure environment, according to a study published in the July issue of Plastic and Reconstructive Surgery.Kim L. Borsky, M.B.B.S., M.D., from the Stoke Mandeville Hospital in the United Kingdom,

Long-term exposure to air pollution is associated with the development of new psoriasis, according to a study published online July 16 in&nbsp;JAMA Network Open.Junhui Wu, Ph.D., from the Peking University School of Nursing in Beijing, and colleagues examined the association between long-term exposure to air pollution and psoriasis an

For patients experiencing migraine, direct calcitonin gene-related peptide (CGRP) inhibition with monoclonal antibodies (mAbs) is associated with reduced rates of acne and rosacea compared with no inhibition (topiramate) or indirect inhibition (triptans), according to a research letter published online July 10 in JAMA Dermatology.Chris

Seven patients with illness identified after presumed cosmetic botulinum neurotoxin (BoNT) product injection are described in a case report published in the July 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Christine M. Thomas, D.O., from the CDC in Atlanta, and colleagues charact

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

The U.S. Food and Drug Administration has approved Zoryve (roflumilast) cream, 0.15 percent, for the treatment of mild-to-moderate atopic dermatitis in adult and pediatric patients (ages 6 years and older).Zoryve is a once-daily, steroid-free cream that the company says will be available at the end of July.The approval was based on resu

Adherence to a Mediterranean diet incorporating eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) reduces skin lesions and improves quality of life in patients with acne, according to a study published online July 10 in the Journal of Cosmetic Dermatology.Anne Guertler, M.D., from Ludwig Maximilian University in Munich, and

Urban-rural disparities in skin cancer prevalence continue to persist, according to a study published in the June issue of the&nbsp;Journal of Drugs in Dermatology.Rachel R. Lin, from the University of Miami Miller School of Medicine, and colleagues used data from the Behavior Risk Factor Surveillance Survey (2018 to 2021) to compare th

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the Journal of the American Academy of Dermatology.Lea Nymand, from Bispebjerg Hospital and the University of Copenhagen in Denmark, and colleagues explored the characteristics of fatigue and it

Among patients with incompletely excised basal cell carcinoma (BCC), only about 16 percent with positive histopathologic margins have clinical recurrence, according to a study published online June 13 in Dermatology.Maria Daviti, M.D., from Aristotle University in Thessaloniki, Greece, and colleagues reported the real-life management of

For patients with prurigo nodularis (PN) and chronic pruritus of unknown origin (CPUO), abrocitinib, a Janus kinase 1 inhibitor, is effective and well tolerated, according to a study published online June 5 in JAMA Dermatology.Shawn G. Kwatra, M.D., from the University of Maryland School of Medicine in Baltimore, and colleagues examine

For patients with resected stage III melanoma, adjuvant therapy with dabrafenib plus trametinib is associated with a nonsignificant benefit in terms of overall survival, according to a study published online June 19 in the New England Journal of Medicine.Georgina V. Long, M.D., Ph.D., from the University of Sydney, and colleagues random

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from