All articles tagged: Dermatology

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the Journal of the American Academy of Dermatology.Lea Nymand, from Bispebjerg Hospital and the University of Copenhagen in Denmark, and colleagues explored the characteristics of fatigue and it

Among patients with incompletely excised basal cell carcinoma (BCC), only about 16 percent with positive histopathologic margins have clinical recurrence, according to a study published online June 13 in Dermatology.Maria Daviti, M.D., from Aristotle University in Thessaloniki, Greece, and colleagues reported the real-life management of

For patients with prurigo nodularis (PN) and chronic pruritus of unknown origin (CPUO), abrocitinib, a Janus kinase 1 inhibitor, is effective and well tolerated, according to a study published online June 5 in JAMA Dermatology.Shawn G. Kwatra, M.D., from the University of Maryland School of Medicine in Baltimore, and colleagues examine

For patients with resected stage III melanoma, adjuvant therapy with dabrafenib plus trametinib is associated with a nonsignificant benefit in terms of overall survival, according to a study published online June 19 in the New England Journal of Medicine.Georgina V. Long, M.D., Ph.D., from the University of Sydney, and colleagues random

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

Lebrikizumab is associated with sustained effects for moderate-to-severe atopic dermatitis for up to week 52 following withdrawal of treatment, according to a study presented at the annual Revolutionizing Atopic Dermatitis Conference, held from June 8 to 10 in Chicago.Jonathan I. Silverberg, M.D., Ph.D., M.P.H., from the George Washington Unive

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

There is no evidence to suggest that administration of live vaccines to patients receiving dupilumab is unsafe, and vaccine efficacy is not affected by dupilumab, according to a position paper published online June 5 in the Annals of Allergy, Asthma &amp; Immunology.Noting that dupilumab targets the interleukin (IL)-4 receptor alpha sub

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Isotretinoin is well tolerated and effective for individuals receiving masculinizing gender-affirming hormonal therapy who have acne, according to a study published online May 29 in JAMA Dermatology.James Choe, from Brigham and Women's Hospital in Boston, and colleagues examined clinical outcomes of isotretinoin among transgender and gen

Among emergency department patients evaluated for an mpox-compatible rash, the prevalence of mpox is 1.5 percent, according to research published in the June 6 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Carl T. Berdahl, M.D., from Cedars-Sinai Medical Center in Los Angeles, and co

Neoadjuvant ipilimumab plus nivolumab followed by surgery results in longer event-free survival than surgery followed by adjuvant nivolumab among patients with resectable, macroscopic stage III melanoma, according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the American Soc

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

Long-term intermittent use of ruxolitinib cream is well tolerated and provides disease control in adolescent patients with atopic dermatitis (AD), according to a study published online May 2 in the&nbsp;American Journal of Clinical Dermatology.Lawrence F. Eichenfield, M.D., from the University of California San Diego, and colleagues asse

Bimekizumab is well tolerated and produces clinically meaningful responses in patients with hidradenitis suppurativa, according to a study published online May 22 in The Lancet.Alexa B. Kimball, M.D., from the Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues examined the efficacy and safety of b

"By examining national trends in patient visits and treatment, we may be able to better inform healthcare utilization for cutaneous wounds," Chandy said.

The finding "highlights the need for further research into tailored treatments for cardiovascular risk in psoriasis patients," Ana Ormaza Vera said.

Black patients with psoriasis had the lowest rate of switching to another biologic therapy compared with other racial and ethnic groups, suggesting possible disparities in treatment patterns.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Dupilumab will be compared with placebo in a larger multicenter randomized trial of children with alopecia.

Results from two phase 3 trials showed that topical tapinarof, once a day, was effective and safe in patients with atopic dermatitis as young as 2 years old.

Parental electronic cigarette use is associated with increased odds of pediatric atopic dermatitis (AD), according to a research letter published online May 22 in JAMA Dermatology.Gun Min Youn, from the Stanford University School of Medicine in California, and colleagues conducted a retrospective cross-sectional analysis of the 2014 to

Parental e-cigarette use was associated with an increased risk for pediatric atopic dermatitis in a retrospective, cross-sectional analysis of US population data.

Use of antihypertensive drugs was associated with a small increase in the rate of eczematous dermatitis diagnoses in older adults, with varying risks with different classes.

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a study published online May 22 in JAMA Dermatology.Morgan Ye, M.P.H., from the University of California in San Francisco, and colleagues examine

An iron profile workup and dermatological findings, such as hyperpigmentation, resistant pruritus, alopecia, and vitiligo, can help diagnose hemochromatosis.

"Our hope is that these findings provide additional data to support Mohs as the standard of care for primary surgical treatment of high-stage cSCC," the study's lead author said.

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

Consensus was reached during an in-person meeting attended by 34 individuals with diverse backgrounds.

The ideal candidate "is averse to using systemic agents but whose disease is beyond the point where topical medicines alone will work," Craig A. Elmets, MD, said.

In pediatric patients, acrochordons may be a marker for metabolic disease, according to a study published online April 29 in Pediatric Dermatology.Rachel K. Greene, M.D., from the University of Michigan in Ann Arbor, and colleagues conducted a single-center retrospective cohort study of outpatient dermatology patients between Jan. 1, 20

There is persistent growth in eBT/SRT by a small but expanding proportion of general dermatologists.

Individuals with BRCA1-associated protein (BAP1) have a high rate of nail abnormalities consistent with onychopapillomas, according to a study published online May 17 in JAMA Dermatology to coincide the annual meeting of the Society for Investigative Dermatology, held from May 15 to 18 in Dallas.Alexandra Lebensohn, from the Nat

More research is "needed to elucidate the unique features of elderly AD in pathophysiology and optimal treatments," the study authors wrote.

Tinea pedis, chronic kidney disease, peripheral vascular disease, and type 2 diabetes were associated with an increased risk for onychomycosis in patients with onychodystrophy.

Acrochordons (skin tags) in children and adolescents may serve as a marker for metabolic diseases.

Overall, version 4.0 of the AI tool performed better than version 3.5.

Adverse effects associated with using the antifibrinolytic were rare.

Non-Hispanic Black (NHB) melanoma patients have distinct tumor characteristics, presenting with more advanced disease and exhibiting worse outcomes, according to a study published in the May issue of the Journal of Surgical Oncology.Jessica A. Steadman, M.B.B.S., from the Mayo Clinic in Rochester, Minnesota, and colleagues examined fe

In its biennial Cancer Disparities Progress Report published today, the American Association for Cancer Research presents the latest statistics on disparities in cancer progress experienced by ethnic-minority groups and other medically underserved populations in the United States.Robert A. Winn, M.D., from the Virginia Commonwealth Un

Exposure to hormones, hyperpigmenting drugs, and multiparity increased risk for melasma across different racial groups in a US study of a diverse population.

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Factors associated with an increased risk for hydroxychloroquine retinopathy have been identified and include female sex, older age, and chronic kidney disease stage 3 or greater, according to a study published online May 9 in JAMA Network Open.April M. Jorge, M.D., from Massachusetts General Hospital in Boston, and colleagues identified

Psoriatic arthritis (PsA) and atopic dermatitis (AD) can coexist, and the presence of both conditions may mean special attention should be given to selecting optimal treatment, according to a study published online April 17 in the Journal of Personalized Medicine.Georgiana Strugariu, from "Grigore T. Popa" University of Medicine and Phar

Most ongoing trials of HS treatments are for moderate to severe disease, Dr Jennifer L. Hsiao said.

Healthcare delivery costs are rising, but there has been a lag in the increase in dermatologic procedure reimbursement rates.

"Early HS can mimic an intense folliculitis or furuncles that can sometimes be caused by Staphylococcus infections," Sayed said.

Physicians' assessment of disease severity and visibility may underestimate the disease's effects on the patient, data suggested.

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

In contrast to earlier findings, immunosuppression was an independent risk factor for disease-specific death and major poor outcomes.

Treatment with adalimumab was associated with improvements in common hematologic abnormalities in patients with hidradenitis suppurativa, particularly in responders.

A pediatric dermatologist proposes a four-step approach to using shared decision-making (SDM) when caring for children and adolescent patients with acne and other skin conditions.

Of the cases accruing in the United States and elsewhere, most but not all were linked to inborn errors of immunity.

Trifarotene plus skin care is beneficial for patients with moderate acne vulgaris (AV) and acne-induced hyperpigmentation (AIH), according to a study published online April 29 in the International Journal of Dermatology.Andrew Alexis, M.D., M.P.H., from Weill Cornell Medical College in New York City, and colleagues conducted a phase IV

Systemic antibiotic exposure in the first year of life is associated with higher atopic dermatitis (AD) risk in a dose-response fashion, according to a study published online April 24 in the&nbsp;Journal of Allergy and Clinical Immunology.Courtney Hoskinson, from the University of British Columbia in Vancouver, Canada, and colleagues e

The IPC's definition and diagnostic criteria for GPP minimized the complexity of clinical considerations to speed treatment of this potentially life-threatening condition.

Antiepileptic and anti-infectious agents were the most common classes tied to SJS-TEN.

Certain minority populations may be at a higher risk of being prescribed opioids post-operatively, which may confer further risks of complications of chronic opioid use.

Almost three quarters of survey respondents reported experiencing psychological and emotional stress or burnout associated with being a Mohs surgeon and 68% reported a musculoskeletal injury.

The survey included 81 dermatologists and 182 medical oncologists at six US-based academic institutions.

A review covers the various skin manifestations seen in patients with CF, which include those related to the disease itself, and those associated with treatments for CF.

Despite improved survival rates and guideline recommendations, many eligible patients with metastatic Merkel cell carcinoma are not receiving immunotherapy.

A machine learning algorithm can identify patients with common variable immunodeficiency disease (CVID) from their electronic health records, according to a study published in the May 1 issue of Science Translational Medicine.Due to the low prevalence and extensive heterogeneity in CVID phenotypes, resulting in delayed diagnoses and tre

A retrospective review that may be the first to examine the topic found differences in mpox symptoms between White non-Hispanic patients and patients of color.

Treatment with methotrexate was not associated with an increased risk for interstitial lung disease (ILD) in patients with dermatomyositis.

Health care professionals should consider stigmatization and bullying in assessing the social and mental health of children and adolescents with chronic skin diseases, according to a study published online April 24 in JAMA Dermatology.Amy S. Paller, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and col

Surface anesthesia prior to thermomechanical fractional injury therapy for wrinkles around the eyes provided adequate comfort, with positive treatment outcomes, a small study found.

A decision on approval is expected in the fourth quarter of 2024.

Healthcare professionals should be aware of the possibility of stigmatization and bullying when assessing the social and mental health of children and adolescents with chronic skin disorders.

"The potential risk of subsequent cardiovascular disease should be considered in the care of patients with PN," according to the study authors.

Pz-cel, which comprises autologous, COL7A1 gene–corrected epidermal sheets, was designed to enable normal type VII collagen expression and facilitate wound healing and pain reduction in RDEB wounds.

Tobacco smoking is negatively associated with resolution of psoriasis symptoms, according to a study published in the April issue of Tobacco Induced Diseases.Yan Qiang, from the School of Medicine at Tongji University in Shanghai, and colleagues explored the influence of smoking on treatment efficacy in patients with psoriasis. The

A calcitonin gene-related peptide inhibitor that is FDA-approved for migraine prevention showed early promise against treatment-resistant redness and flushing of rosacea.

Atopic dermatitis (AD) negatively impacts patients’ mental health (MH), especially when a patient has severe AD, according to a study published online March 14 in&nbsp;Dermatitis.Jessica K. Johnson, M.P.H., from the National Eczema Association in San Rafael, California, and colleagues evaluated patient-reported MH symptoms and their c

The authors "identified a need for expert-based guidelines for prescribing and monitoring LDOM use in hair loss patients."

Expect intradermal injections of botulinum toxin A for the improvement in the appearance of pores, sebum, skin texture, and rosacea to gain a foothold in dermatology practices, one expert says.

A small study of the 2910-nm erbium-doped fluoride glass fiber laser for facial ablation showed that patients had faster recovery times and less pain than with conventional lasers.

An analysis evaluated growth in a study of 1326 children with AD younger than 12 years.

Cutaneous manifestations of myelodysplastic syndrome (MDS) are described in a perspective piece published in the April issue of Skin Health and Disease.Xiang Li Tan, M.B.B.S., from St. George's University Hospitals NHS Foundation Trust in London, and colleagues conducted a systematic review to examine the prevalence, types, and prognos

A 532-nm picosecond laser with fractional-beam microlens array to treat solar lentigines resulted in a lower hyperpigmentation rate in patients with darker skin types, vs the full-beam approach.

A registry of adverse events from dermatologic procedures found that blistering, hypopigmentation, scars, and burns are the most common complications from laser and energy devices.

Laser and light hair treatments, with and without other treatments, improve hirsutism and related psychological measures in women with PCOS.

Once-weekly PDL treatment in infants led to near-total or total clearance of PWB and was well-tolerated in 10 infants, suggesting further investigation of the reduced treatment interval of 1 week.

The anticalcitonin gene-related peptide-receptor monoclonal antibody erenumab is effective and safe for treatment of rosacea-associated erythema and flushing, according to a study published online April 17 in JAMA Dermatology.Nita K.F. Wienholtz, M.D., Ph.D., from Copenhagen University Hospital-Rigshospitalet in Denmark, and colleag

Rapidly progressive interstitial lung disease was diagnosed in almost half of the patients with MDA5 antibody-positive dermatomyositis.

Reactions have included blurry vision, double vision, drooping eyelids, difficult swallowing or breathing, and other symptoms of botulism.

Counterfeit or mishandled Botox shots have triggered harmful reactions in 19 people in nine states, U.S. health officials warned Monday.In its alert, the U.S. Centers for Disease Control and Prevention said nine people had been hospitalized and four we

Study finds that people who have complications after cosmetic procedures have higher rates of depression, anxiety, and other mental health issues than before the procedures.

The American Society for Dermatologic Surgery Association emphasized the risks for medical procedures in unlicensed settings.

In this literature review, researchers found that neuromodulators and dermal fillers are useful and safe in SOC populations, although more data are needed in some groups.

Pediatric dermatology-rheumatology combined clinics improve patient outcomes and satisfaction.

Reports of keratoacanthomas and squamous cell carcinomas associated with the use of PD-1/PD-L1 inhibitors appeared to be relatively rare.

Response curves have continued to climb for as long as patients are followed, allowing many with disappointing early results to catch up, according to data presented at the AAD meeting.

Over 1 year after phase 3 studies suggested that delgocitinib cream was safe and effective for chronic hand eczema, extension data indicate that control persists without new safety issues.

Efficacy and safety of the two formulations were directly compared in a randomized, controlled, double-blind study of men with AGA conducted in Brazil.

"This study explored why dermatologists still prescribe a good number of long-term antibiotics for people with acne," the study's senior author Howa Yeung, MD, MSc, said in an interview.

Multiple salient factors affect long-term antibiotic prescribing practices for acne, according to a study published online April 3 in JAMA Dermatology.Ronnie A. Festok, from the Emory University School of Medicine in Atlanta, and colleagues conducted a qualitative study assessing data collected from stakeholders (dermatologists, inf

Stabilized bioactive retinol is efficacious for improving signs of photoaging, without causing major irritation, according to a study published in the April issue of the Journal of Drugs in Dermatology.Patricia Farris, M.D., from Tulane University School of Medicine in New Orleans, and colleagues examined the comprehensive efficacy

Individuals with zoom dysmorphia tend to scrutinize their facial features and fixate on what they think needs to improve and feel pressured to appear perfect before virtual meetings.

A prospective Swedish study reported that childhood atopic dermatitis is linked to an increased risk for inflammatory bowel disease.

Phase 4 involves initiating therapy, which includes demonstrating empathy by reflecting on the detrimental effects of the patient's reported sensations on their quality of life.

Sonelokimab is a novel humanized nanobody that selectively binds to interleukin (IL)-17A and IL-17F.

The U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults with Staphylococcus aureus bloodstream infections, adults with acute bacterial skin and skin structure infections, and adult and pediatric patients (age 3 months

Recent research sheds light on varying skin cancer risk, and a predictive tool offers guidance on screening in solid organ transplant recipients.

With sparse guidance regarding best practices for IHC in melanoma diagnosis, more research is needed to optimize use of IHC in this setting, according to the authors.

Bimekizumab is currently approved in the United States for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.

Alopecia, dysesthesia, and other types of skin sensations have been reported in patients treated with semaglutide, but more research is needed to understand skin findings associated with this drug.

Patients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a study published online March 19 in the Journal of the American Academy of Dermatology.Lauren Banner, from Thomas Jefferson University in Philadelphia, and colleagues used the Surveillance, Epidemiolo

Rilzabrutinib did not meet primary or secondary endpoints in the phase 3 PEGASUS trial of patients with pemphigus vulgaris or foliaceus.

Treatment with the topical JAK inhibitor reduced abscess and inflammatory nodules in a phase 2 randomized, controlled trial in patients with mild hidradenitis suppurativa.

Alternatives to SA and cryotherapy for warts may be helpful "for patients who have failed traditional therapies or have a contraindication to the usual go-tos," said Dr Jennifer Adams.

Two JAK inhibitors for non-segmental vitiligo showed better skin clearance in phase 2b trial extensions — ritlecitinib plus twice-weekly doses of UVB light and upadacitinib.

Study found that hypoplastic pitted amelogenesis imperfecta is among the oral manifestations of Kindler epidermolysis bullosa, underscoring the need for early and sustained dental care.

Pediatric longitudinal melanonychia may look like subungual melanoma in adults, but a low probability of malignancy makes clinical monitoring a reasonable noninvasive management strategy.

U.S. physicians received $12.13 billion from industry from 2013 to 2022, according to a research letter published online March 28 in the Journal of the American Medical Association.Ahmed Sayed, M.B.B.S., from Ain Shams University in Cairo, and colleagues examined the distribution of payments within and across specialties and the medica

Some pain-relieving skin products contain potentially harmful doses of the numbing agent lidocaine and should be avoided, the U.S. Food and Drug Administration warns.These creams, gels, sprays and soaps are marketed for topical use to relieve the pain of cosmetic procedures like microdermabrasion, laser hair removal, tattooing and <a href="http

The warning applies to unapproved products illegally marketed for topical use to relieve pain before, during, or after cosmetic procedures.

Products containing glyoxylic acid were associated with the accumulation of calcium oxalate crystals in the kidneys.

Time spent on social media and use of photo-editing applications contribute to the desire to undergo a cosmetic procedure, according to a study recently published in the&nbsp;Journal of Clinical and Aesthetic Dermatology.Iman F. Khan, M.D., M.P.H., from Boston University, and colleagues surveyed 175 adults visiting an outpatient dermat

Many patients, including those with the greatest care needs, choose telemedicine even when in-person visits are available, according to a study published online March 22 in&nbsp;JAMA Network Open.Eva Chang, Ph.D., M.P.H., from Advocate Health in Milwaukee, Wisconsin, and colleagues assessed patient characteristics associated with telem

Most patients report an increase in trust in the quality of their medical care if asked for permission to use their images for research or education, according to a research letter published online March 13 in JAMA Dermatology.Trina Salvador, from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues conducted a s

Physicians express largely negative views about the impact of private equity (PE) on the health care system, according to a research letter published online March 11 in&nbsp;JAMA Internal Medicine.Jane M. Zhu, M.D., from Oregon Health and Science University in Portland, and colleagues conducted a survey to assess physicians' views towa

In a citizen's petition, Valisure asked the FDA to recall acne products with benzoyl peroxide, stirring debate.

Life expectancy increased to 77.5 years in 2022, while the age-adjusted rate of drug overdose deaths increased from 2002 to 2022 but did not change from 2021 to 2022, according to two March data briefs published by the National Center for Health Statistics.Kenneth D. Kochanek, from the National Center for Health Statistics in Hyattsville, Mar

Artificial intelligence is coming to clinical dermatology, but its enormous promise for improving the lives of patients and physicians will depend on addressing the expected problems.

A study suggested that immunomodulatory medications do not increase the risk for COVID-19 related hospitalizations in patients who have received the COVID-19 vaccine.

In the study, 28.5% of the adolescents and young adults experienced worsening acne after insertion of a progestin-only long-acting reversible contraceptive, and 17% reported acne as a new concern.

Spesolimab-sbzo was initially approved in 2022 for treating flares of generalized pustular psoriasis in adults.

The annual meeting of the American Academy of Dermatology was held from March 8 to 12 in San Diego and attracted participants from around the world, including clinicians, academicians, allied health professionals, and others interested in dermatology. The conference highlighted recent advances in the diagnosis and management of d

For adults with alopecia areata, continuous improvements are seen through 68 weeks with deuruxolitinib, according to a study presented at the annual meeting of the American Academy of Dermatology, held from March 8 to 12 in San Diego.Brett King, M.D., Ph.D., from the Yale School of Medicine in New Haven, Connecticut, and colleagues reported po

Among patients treated with roflumilast cream, 0.05%, 25.4% reached the primary endpoint of "clear" or "almost clear" plus a two-grade improvement from baseline at week 4.

Lebrikizumab demonstrates improvement in skin clearance and itch relief in patients with skin of color and moderate-to-severe atopic dermatitis, according to a study presented at the annual meeting of the American Academy of Dermatology, held from March 8 to 12 in San Diego.Andrew Alexis, M.D., M.P.H., from Weill Cornell Medicine in New York Ci

MONDAY, March 18, 2024 (HealthDay News) --&nbsp;Continuous treatment with baricitinib in patients with severe alopecia areata demonstrates improvement in hair regrowth outcomes through 76 weeks of follow-up, according to a study presented at the annual meeting of the American Academy of Dermatology, held from March 8 to 12 in San Diego.Rodney D. Sinclair, M.D., from the University of Me

Testosterone therapy can exacerbate symptoms, and other factors are important to consider, expert said.

Short-term exposure to wildfire-related air pollution is associated with an increase in clinic visits for acne vulgaris among adults, according to a study presented at the annual meeting of the American Academy of Dermatology, held from March 8 to 10 in San Diego.Alex Ha, from the University of California, San Francisco, and colleagues conducte

FRIDAY, March 15, 2024 (HealthDay News) --&nbsp;Patients with psoriasis treated with bimekizumab rapidly achieve high levels of clinical and health-related quality-of-life responses that are durable at four years, according to research presented at the annual meeting of the American Academy of Dermatology, held from March 8 to 10 in San Diego.Bruce Strober, M.D., Ph.D., from the Yale Sc

The encouraging long-term efficacy and safety associated with nemolizumab (IL-31 inhibitor) in prurigo nodularis was supported by a second set of data showing long-term benefit in atopic dermatitis.

A recent study demonstrated that 94% of top-selling baby cleansers contain allergens, despite having hypoallergenic claims.

Following a cyberattack on one of the nation's largest health insurers that's thrown health care payments into disarray and likely exposed reams of private patient data, the U.S. Department of Health and Human Services said Wednesday it has begun an investigation into the incident.In a&nbsp;<a href="https://www.hhs.gov/about/news/2024/03/13/h

Two oral therapies targeted at kinase pathways produced meaningful responses in patients with severe types of alopecia in late-breaking studies at the American Academy of Dermatology.

Some 321,000 state employees would be eligible, at a cost of about $357,000 per year, according to one analysis.

Following a cyberattack on the largest health insurer in the United States last month, health care providers continue to scramble as insurance payments and prescription orders continue to be disrupted and physicians lose an estimated $100 million a day.That <a href="https://www.ama-assn.org/press-center/press-releases/cyberattack-jeopardizes

A coauthor of the new recommendations highlights updated advice and comments on worrisome benzene news.

Pediatric atopic dermatitis (AD) is&nbsp;associated with greater odds of reported difficulties in learning and memory, but this association is driven by children with neurodevelopmental comorbidities, according to a study published online March 6 in&nbsp;JAMA Dermatology.Emily Z. Ma, from the University of Maryland School of Medicine

Interim results at 16 weeks were based on 50 adolescents and adults with skin types IV-VI.

The study population included nearly 1.3 million children born in Quebec, Canada, over a 16-year period.

Both an approved anti-IL-17 therapy and an experimental oral anti-IL-23 therapy appeared to achieve relatively undiminished rates of psoriasis control in extension studies.

The multicenter LITE trial included 783 patients at 42 sites in the United States.

Several drugs should be avoided or used with caution because of potential risks during pregnancy, a dermatologist told colleagues.

NCCN guidelines for cutaneous melanoma, issued in February, capture evolving data for both diagnosis and treatment, diverging incrementally from 2019 AAD guidelines.

The findings suggest that Bruton's tyrosine kinase inhibition may emerge as a promising therapeutic intervention in HS.

Up to 15% of the general population is affected by a personality disorder, according to dermatologist, Mio Nakamura, MD.

There are notable concerns relating to the use of currently available artificial intelligence (AI) dermatology mobile applications (apps), according to a study published online March 7 in JAMA Dermatology to coincide with the annual meeting of the American Academy of Dermatology, held from March 8 to 10 in San Diego.Shannon Wongvibulsin

A controversial proposal to end the American Academy of Dermatology diversity programs will be considered at the group's annual meeting starting today.

Experts lobby for increased inclusion of sulfites in patch test panels.

Only three of 13 psoriasis biologics appeared to be cost-effective based on US prices in a new analysis. The finding may aid policymakers struggling with drug price negotiations.

Some acne treatments may banish blemishes but carry hidden dangers: A new report reveals high levels of the carcinogen benzene can form in products that contain the zit-fighting ingredient benzoyl peroxide.According to the new&nbsp;report from

The analysis included children aged 17 years or younger without intellectual disability or autism.

Challenges relating to artificial intelligence (AI) in dermatology and its application to skin of color (SOC) are partly due to underrepresentation of SOC in datasets, according to research published online March 6 in the International Journal of Dermatology.Rebecca Fliorent, from the Rowan-Virtua School of Osteopathic Medicine in St

In a randomized, controlled trial, 59% of adults reported experiencing at least one treatment site response.

For scalp psoriasis, 0.1 percent tacrolimus microemulsion has good efficacy and safety, according to a study published online Feb. 12 in Dermatology and Therapy.Andreas Pinter, M.D., from the University Hospital Frankfurt in Germany, and colleagues conducted a multicenter, double-blind, vehicle-controlled phase 3 trial to examine the e

Health care portal use was higher during the COVID-19 pandemic, according to a study published online Feb. 29 in JAMA Network Open.Esther Yoon, Ph.D., M.P.H., from the Feinberg School of Medicine at Northwestern University in Chicago, and colleagues examined the prevalence of health care portal use before, during, and after the most re

The product has been sold in more than 50 countries, the company says.

The study results "highlight the importance of patient-reported outcomes in measuring this disease," the study's lead author said.

Atopic dermatitis "could serve as a case study for climatic impacts on health," the authors emphasized in their paper.

Over 5 years, treatment with spironolactone for dermatologic conditions was not associated with a greater risk for breast or gynecologic cancers, when compared with women not using spironolactone.

The findings may have potential implications for more personalized surveillance of patients with melanoma, the authors said.

Delays in melanoma diagnoses due to COVID-19 pandemic lockdowns were associated with a significant burden, including years of life lost and costs, according to a study published online Feb. 16 in&nbsp;JAMA Network Open.Lara V. Maul, M.D., from University Hospital of Basel in Switzerland, and colleagues examined the consequences associa

Joint pain and itch were key culprits, according to a cross-sectional analysis of Danish data.

During the COVID-19 pandemic, cancer diagnoses were lower than expected, according to a study published online Feb. 22 in JAMA Oncology.Todd Burus, from the Markey Cancer Center at the University of Kentucky in Lexington, and colleagues conducted a population-based cross-sectional analysis of cancer incidence trends using data on cases

In a cross-sectional study of the social media platform, researchers analyzed 50 videos on the topic.

Evidence to support the hypothesis that the use of systemic immunomodulatory agents for psoriasis "quenches systemic inflammation and potentially improves" survival is limited, investigators said.

Women in health care occupations endure a significantly higher level of stress and burnout than men, according to a study published online Feb. 21 in Global Advances in Integrative Medicine and Health.Viktoriya Karakcheyeva, M.D., from the George Washington University School of Medicine and Health Sciences in Washington, D.C., and colle

The biosimilar Pyzchiva is highly similar to Stelara, which was approved in the EU in 2009.

One hospital's experience with this model shows the efficiency of using a dedicated team (including trainees) and offering same-day biopsies and surgery.

2019 treatment guidelines published recommended ertapenem as a highly effective third-line therapy limited to a shorter course, as rescue therapy or during surgical planning.

First Lady Jill Biden on Wednesday announced $100 million in federal funding to fuel research into women's health.“We will build a health care system that puts women and their lived experiences at its center,” Biden said in a White House <a href="https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/02/21/remarks-as-prepared-for-deliv

NICE said there is unequal treatment for people with severe alopecia areata across England and Wales and its approval of ritlecitinib could benefit up to 14,000 people.

Treatment of hidradenitis suppurativa (HS) with intravenous ertapenem is associated with improvement in clinical and inflammatory markers, according to a study published online Feb. 19 in JAMA Dermatology.Avigdor Nosrati, M.D., from the Albert Einstein College of Medicine in New York City, and colleagues conducted a retrospective rev

Unexpected medical bills and high health care costs are dominating an election where kitchen table economic problems weigh heavily on voter’s minds, a new KFF poll has found.Voters struggling to pay their monthly bills are most eager to hear presidential candidates talk about economic and health care issues, according to the latest KFF Health

For prurigo nodularis, the FDA has granted nemolizumab, a monoclonal antibody designed to inhibit interleukin-31 signaling, priority review.

Skin conditions both specific and nonspecific to IBD are prevalent in children and adolescents with IBD, with infectious conditions being the most common.

Amtagvi (lifileucel) has been approved by the U.S. Food and Drug Administration for the treatment of advanced melanoma. Amtagvi becomes the first cellular therapy approved to treat this form of solid tumor cancer."The approval of Amtagvi offers hope to those with advanced melanoma who have progressed following initial standard-of-care therapies

The U.S. Food and Drug Administration has expanded the use of the asthma drug Xolair (omalizumab) to help prevent anaphylactic reactions.Xolair is an injected drug and is not meant as a substitute for EpiPens or other anaphylaxis rescue remedies, the agency stressed. Instead, "Xolair is intended for repeated use to reduce the risk of allergic re

Deep learning-aided decision support improves diagnostic accuracy for skin disease, according to a study published online Feb. 5 in Nature Medicine.Matthew Groh, Ph.D., from the Northwestern University Kellogg School of Management in Evanston, Illinois, and colleagues presented results from a study involving 389 board-certified dermatol

The findings build on results from a 12-week study of the device, which the investigators said "induces physical shearing of fibrous septa through rapid acoustic pulses."

Approved in 2022 for psoriasis, the manufacturer has submitted an application for approval of tapinarof cream for treating atopic dermatitis in adults and children 2 years of age and older.

Aurlumyn (iloprost), a vasodilator, has been approved by the U.S. Food and Drug Administration to treat severe frostbite. The injected medication lowers the risk for finger or toe amputation."This approval provides patients with the first-ever treatment option for severe frostbite," Norman Stockbridge, M.D., director of the Division of Cardiol

Access disparities to burn centers persist, with lower access in the South and West and for those with lower income, according to a research letter published online Feb. 14 in JAMA Surgery.Dong Gi Hur, from the Stanford School of Medicine in California, and colleagues characterized access to American Burn Association (ABA)-verified a