All articles tagged: Gastroenterology

Gastroenterologists who focus primarily on providing inpatient care, called GI Hospitalists, are becoming more common across the U.S. Researchers at Brigham and Women's Hospital developed a survey to assess the effect of GI Hospitalists on fellowship education and found that GI Hospitalists improve education through superior endoscopy teaching and longitudinal feedback.

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.

Transplant rates and waitlist dropouts for women are now similar to those for men, yet some disparities still exist.

Even though adding HPSA testing to a colon cancer screening program did not reduce the incidence or mortality rates of gastric cancer, potential benefits were still observed.

A study found that GLP-1 RA use is linked to risks for retained gastric contents during single endoscopic procedures but not with combined upper endoscopy and colonoscopy.

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

The increasing incidence of pancreatic cancer in young Americans is mainly due to increased detection of smaller, early-stage endocrine cancer, according to a research letter published online Nov. 19 in the Annals of Internal Medicine.Vishal R. Patel, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and colleagues examined wh

Patients with IBD don’t face an increased risk for major adverse cardiovascular events when taking Janus kinase inhibitors compared with anti-TNF agents.

Intermittent calorie restriction followed for 2 nonconsecutive days per week reduced the liver fat content in patients with MASLD more effectively than the standard diet.

Aggressive infliximab dosing did not provide additional clinical benefits for patients with steroid-refractory acute severe ulcerative colitis compared with standard dosing.

Initiating biologic therapy early in order to achieve transmural healing led to better long-term outcomes in patients with Crohn's disease.

For patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC), chemoradiotherapy (CRT) followed by immunochemotherapy (iCT) and then surgery is promising, according to a study published online Nov. 15 in Clinical Cancer Research.Xin Wang, from the Chinese Academy of Medical Sciences and Peking Union Medical C

Given the increasing prevalence and mortality rates, targeted strategies are needed to reduce this growing health burden in older adults.

For colorectal cancer screening, colonoscopy and stool tests are more effective and less costly than novel first-generation blood tests, a modeling study has found.

As the holidays approach, most folks are familiar with a common side effect of the overindulgence that can come with all those meals with family and friends: Bloating.

Metabolic dysfunction-associated steatotic liver disease (MASLD) prevalence is high among U.S. adults, according to a study published online Oct. 29 in Communications Medicine.Luis Antonio Díaz, M.D., from the University of California San Diego, and colleagues assessed racial and ethnic disparities in the SLD prevalence among U.S. adult

Newly diagnosed pancreatic cancer patients receiving palliative care (PC) consultations have an increased prevalence of anxiety and depression, according to a study recently published in Healthcare.Divya S. Subramaniam, Ph.D., M.P.H., from the Saint Louis University School of Medicine, and colleagues conducted a retrospective analysis o

A new study provides more evidence that GLP-1 RAs don’t raise the risk for pancreatic cancer and may in fact offer some protection.

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

Scientists at UMC Utrecht have developed a new technology to efficiently isolate a specific subset of gut bacteria from fecal samples that are recognized by IgA antibodies. These "IgA-coated" bacteria are associated with an array of diseases and this proposed new technology has the potential to uncover the mechanisms behind these correlations and eventually lead to new treatment strategies.

GI bleeding after percutaneous coronary intervention among patients on dual antiplatelet therapy remains risky in terms of morbidity and mortality, but a predictive tool could help.

Endoscopic sleeve gastroplasty is a safe and effective treatment for obesity, with durable long-term results for at least 10 years after the procedures, new data showed.

Patients with alcohol-associated liver disease could benefit from treatment of alcohol use disorder, yet pharmacologic therapy remains underutilized in this at-risk group.

At-risk individuals who progress to rheumatoid arthritis (RA) have a distinctive gut microbial composition, according to a study published online Nov. 7 in the Annals of the Rheumatic Diseases.Christopher M. Rooney, from the University of Leeds in the United Kingdom, and colleagues examined structural, functional, and temporal changes

A randomized controlled trial finds no clear benefit of adding bezlotoxumab to FMT in patients with IBD and recurrent C difficile infection.

The annual meeting of the American College of Gastroenterology was held from Oct. 25 to 30 in Philadelphia and attracted participants from around the world, including gastroenterology and digestive disease specialists and other health care professionals. The conference featured presentations focusing on clinical updates in gastroenterology an

COVID-19 is associated with long-term risk for autoimmune and autoinflammatory connective tissue disorders, according to a study published online Nov. 6 in JAMA Dermatology.Yeon-Woo Heo, M.D., from the Yonsei University Wonju College of Medicine in South Korea, and colleagues conducted a retrospective cohort study to examine the long-ter

Patients with celiac disease who take an angiotensin receptor blocker (ARB) may experience worse outcomes, such as iron deficiency, diarrhea, and abdominal pain.

The majority of patients may safely take glucagon-like peptide 1 receptor agonists before elective surgery and gastrointestinal endoscopies.

The rate of HCV reinfection was high in the immediate posttreatment period among individuals who injected drugs but decreased significantly over time.

A meta-analysis found no association between cardiovascular events and the commonly used gastric acid suppressants, despite a relatively higher rate of this adverse event in trials of reflux disease.

AI-assisted colonoscopy improved adenoma detection compared with routine colonoscopy, regardless of the endoscopist’s experience, technology system, or healthcare setting.

For teens undergoing bariatric surgery, weight loss and remission of coexisting conditions are durable after 10 years, according to a research letter published online in the Oct. 30 issue of the New England Journal of Medicine.Justin R. Ryder, Ph.D., of the Ann and Robert H. Lurie Children’s Hospital of Chicago, and colleagues reporte

Lower abdominal visceral fat area (VFA), older age, and prolonged surgery are independent risk factors for developing postoperative neurogenic bladder (PONB) after rectal cancer surgery, according to a study published online Sept. 27 in BMC Gastroenterology.Tomohiro Matsui, M.D., from Kyoto Prefectural University of Medicine in Japan,

Serum zinc is often deficient in patients with liver cirrhosis and hepatic encephalopathy (HE), according to a study published online in the September issue of the Journal of Family Medicine and Primary Care.Divakar Kumar, M.D., from the Rajendra Institute of Medical Sciences Ranchi in India, and colleagues measured the serum

In a novel study that identified male chromosome genetic material in the intestines of female patients undergoing fecal transplants, researchers at Johns Hopkins Medicine say they have significantly expanded scientific understanding of how some of these transplants may succeed and work.

Most people continue to believe that pancreatic cancer affects only the elderly and that there is nothing they can do to reduce their risk, according to the results of a new survey from The Ohio State University.A national web- and telephone-based survey (Oct. 4 to 7) of 1,004 respondents was conducted by The Ohio State University Comprehensive

In a new study, researchers at the University of Copenhagen have been cultivating "good viruses" from feces. The goal is to replace fecal capsules now being used in so-called fecal transplants. Their new technique has shown potential in studies with mice and the hope is that it will improve this life-saving treatment through standardization and pave its way toward mainstream medicine.

IBS has classically been regarded as a “diagnosis of exclusion,” but new research suggested that might be changing with better diagnostic and treatment approaches.

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

More than one-third of patients have emergency department use within 90 days before a confirmed cancer diagnosis, according to a study published online Nov. 4 in CMAJ, the journal of the Canadian Medical Association.Keerat Grewal, M.D., from Sinai Health at the University of Toronto, and colleagues conducted a retrospective, population-b

Everyone knows that colonoscopies save lives, but that doesn't make drinking a lot of liquid laxatives in preparation for the procedure any less daunting.

New research challenges the traditional practice of continuing vasoconstrictor therapy for 5 days after endoscopic variceal ligation for acute variceal bleeding.

AI-assisted colonoscopy with computer-aided detection technology may improve adenoma detection rate, but it’s also associated with greater removal of non-neoplastic lesions.

Researchers behind a randomized trial also found that eradication rates were significantly lower in patients with a BMI ≥ 23.5 taking proton-pump inhibitor–based triple therapy.

Lack of health insurance coverage accounts for a considerable proportion of racial and ethnic disparities in advanced-stage diagnoses of cancer, according to a study published online Oct. 30 in the Journal of the National Cancer Institute.Parichoy Pal Choudhury, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can decrease the risk for developing early-onset colorectal cancer (EO-CRC) in patients with diabetes regardless of weight, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Temitope Olasehinde, M.D., from

Findings from a meta-analysis comparing surgical and pharmacologic weight loss interventions also highlighted the clinical value of bariatric endoscopy, which had a favorable side-effect profile.

Early-onset colorectal cancer (EO-CRC) mortality rose in the United States over the past two decades, most notably in patients aged 20 to 44 years, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.

Hormone replacement therapy (HRT) is associated with an increased risk for developing irritable bowel syndrome (IBS) in postmenopausal women, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.

Stents to treat various blockages in the human body can themselves become blocked, but a new sensor developed at the University of Michigan for stents that are used in the bile duct may one day help doctors detect and treat stent blockages early, helping keep patients healthier.

Early-onset colorectal cancer (EO-CRC) mortality rose in the United States over the past two decades, most notably in patients aged 20 to 44 years, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Yazan Abboud, M.D., from Rutgers New Jersey Medical School

Hormone replacement therapy (HRT) is associated with an increased risk for developing irritable bowel syndrome (IBS) in postmenopausal women, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Jacqueline Khalil, D.O., from Case Western Reserve University in

Many people find that wheat or gluten cause them to react in some way: Some people have a wheat allergy, some have the autoimmune condition celiac disease, but the majority find they have some sort of intolerance or sensitivity to wheat and gluten.

There is a positive causal relationship between gastroesophageal reflux disease (GERD) and hypertension, according to a study published online Sept. 23 in Frontiers in Cardiovascular Medicine.Weige Li, from the Jiangxi University of Chinese Medicine in Nanchang, China, and colleagues investigated the causal relationship between

There are small but important differences in risk for some clinical outcomes associated with rosuvastatin and atorvastatin, according to a study published online Oct. 29 in Annals of Internal Medicine.Shiyu Zhou, M.D., from Southern Medical University in Guangzhou, China, and colleagues compared the real-world effectiveness and

Cell-free DNA blood tests (cf-bDNA) may be more costly and less effective for colorectal cancer (CRC) screening than other screening modalities, according to a study published online Oct. 29 in the Annals of Internal Medicine.Uri Ladabaum, M.D., from the Stanford University School of Medicine in California, and colleagues estimated t

Low-volume bowel preparation is noninferior in adequacy to standard-volume prep in hospitalized patients undergoing colonoscopy.

Participants who responded to low FODMAP diets had higher hydrogen and lower methane levels at baseline than nonresponders.

An international research team has developed an AI tool that is highly accurate in detecting and differentiating pleomorphic pancreatic lesions.

Restaging magnetic resonance imaging (MRI) can predict organ preservation and survival with rectal cancer, according to a study published online Sept. 3 in Radiology.Hannah Williams, M.D., from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues evaluated the ability of restaging MRI to predict oncolog

New data showed similar FIT completion rates and yield in younger and older adults, supporting stool-based CRC screening as the initial modality in younger populations.

Using COVID-19 vaccine technology, researchers created an mRNA vaccine targeting C difficile, showing strong immune responses in animal studies.

A large retrospective study, the first of its kind, reported reduced rates of EO-CRC in patients younger than 50 years of age taking the antidiabetic medications.

For patients with a history of overt hepatic encephalopathy (OHE), rifaximin monotherapy (MT) results in significantly fewer OHE episodes than lactulose (LAC) MT, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Jasmohan S. Bajaj, M.D., from Virginia Commonw

AI-enhanced colonoscopy improves the overall detection of polyps and adenomas, but maybe not advanced neoplasia, according to a new meta-analysis.

The success surrounding the medications for obesity and diabetes has sparked research into whether they could also be an effective treatment for MASLD and MASH. The early results look promising.

New evidence shows how we evolved to crave and digest carbohydrates and how this helped spur today’s carbohydrate consumption beyond healthy amounts.

An analysis of the two largest US mortality databases found the risk of mortality due to early-onset colorectal cancer most pronounced in those aged 20-44 years.

Taking a GLP-1 receptor agonist was associated with a lower risk for cirrhosis and related complications in patients with metabolic dysfunction–associated steatotic liver disease and diabetes.

For patients with type 2 diabetes (T2D), duodenal recellularization via electroporation therapy (ReCET), which uses pulsed electric fields to induce natural cell death through an apoptosis-like process, is feasible and safe and can prevent the need for insulin therapy when combined with semaglutide, according to a study presented at UEG Week, the ann

To address childhood malnutrition—which affects 200 million children globally—researchers at Washington University School of Medicine in St. Louis have developed a therapeutic food that nourishes the collection of beneficial microbes that reside in the gut, and improves children's growth and other measures of their health. But to understand just how this food therapy works, the research team led b

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

The U.S. Food and Drug Administration has approved Vyloy (zolbetuximab-clzb) in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma who

Fecal immunochemical test (FIT) completion and yield rates are similar in people aged 45 to 49 years and those aged 50 years, according to a study published online Oct. 22 in the Annals of Internal Medicine.Theodore R. Levin, M.D., from Kaiser Permanente Northern California in Oakland, and colleagues examined FIT completion and yield i

Compared with conventional colonoscopy, computer-aided detection (CADe) system-enhanced colonoscopies have an increased rate of adenomas per colonoscopy and higher adenoma detection rates, according to a review published online Oct. 22 in the Annals of Internal Medicine.Saeed Soleymanjahi, M.D., M.P.H., from Mass General Brigham and th

In patients with moderate to severe Crohn’s disease, guselkumab showed similar efficacy in both biologic-naive and biologic-inadequate responders.

Measures of social support are associated with screening for specific types of cancer, according to a study published online Oct. 18 in Cancer Causes &amp; Control.Jordan Baeker Bispo, Ph.D., M.P.H., from the American Cancer Society in Atlanta, and colleagues examined the impact of living arrangements and residential stability on cancer

Patients with inflammatory bowel disease (IBD) continue to experience barriers to health care access and treatment and financial struggles, according to a study published online Oct. 8 in&nbsp;Inflammatory Bowel Diseases.Ariel A. Jordan, M.D., from University of Michigan in Ann Arbor, and colleagues surveyed IBD patients and their careg

A research team has investigated how mucin, a major component of the gut lining, and food-derived glycoproteins influence the growth of the bacterium Akkermansia muciniphila. By dissecting the role of mucin's protein and glycan components, researchers reveal the complex interactions between diet and gut bacteria, offering insights for future therapeutic applications.

Noninvasive surveillance with multitarget stool DNA testing or fecal immunochemical testing could potentially match colonoscopy for reducing colorectal cancer incidence.

For patients with ulcerative colitis, the HLA-DRB1*01:03 allele is associated with severe ulcerative colitis, according to a research letter published online Oct. 15 in the Journal of the American Medical Association to coincide with the United European Gastroenterology Week, held from Oct. 12 to 15 in Vienna.Marie Vibeke Vestergaard, f

A bidirectional relationship exists between inflammatory bowel disease and type 1 diabetes, which warrants heightened awareness to facilitate earlier detection of both diseases.

Interim phase 3 results showed the IL-13 monoclonal antibody improves histology and symptoms in EoE, even in participants with inadequate response or intolerance to steroids.

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion. In response to incoming food, these hormones are secreted by rare hormone producing cells in the gut and play key roles in managing digestion and appetite.

The HLA-DRB1*01:03 allele was significantly associated with increased severity of ulcerative colitis, including higher rates of hospitalization, surgery, and corticosteroid use.

A diet high in ultraprocessed foods can raise the relapse risk in patients with Crohn’s disease who are in remission, with some subgroups of those foods increasing that risk approximately threefold.

There is an imbalance in the gut flora of patients with epilepsy compared with healthy controls, according to a study published online Sept. 28 in the&nbsp;Journal of Health, Population and Nutrition.BingCong Hong, from the Quanzhou First Hospital Affiliated to Fujian Medical University in China, analyzed differences in gut flora bet

Using computer-aided diagnosis to differentiate neoplastic from non-neoplastic polyps is more effective in the distal colon than in the proximal colon, according to a systematic review and meta-analysis.

Participants with type 2 diabetes who stopped insulin after receiving the novel ReCET endoscopic procedure in combination with semaglutide maintained their initial response at 2 years.

For the first time, researchers looked at the pancreatic enzyme replacement therapy (PERT) dose needed to achieve therapeutic goals in patients with EPI according to the underlying cause.

A stapler that produces a straight gastric sleeve in one fire improved the efficiency and perioperative outcomes of laparoscopic sleeve gastrectomy, compared with sequential staple firing.

For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association.Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital -- Herlev a

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

Delays in cancer registration probably led to a major underestimation of the effectiveness of screening colonoscopy in reducing colorectal cancer risk in the controversial NordICC trial.

Evidence suggested there is little risk in administering the live rotavirus vaccine to the babies of mothers on biologics during pregnancy for inflammatory bowel disease.

For individuals with obesity, metabolic-bariatric surgery (MBS) is associated with a reduced risk for pancreatic cancer, especially among those with type 2 diabetes (T2D), according to a review published online Oct. 9 in Diabetes/Metabolism Research and Reviews.Angeliki M. Angelidi, M.D., Ph.D., from the Broad Institute of MIT and Har

A study comparing fenestrating and reconstituting partial cholecystectomies found no major long-term differences between the two.

Automated speech analysis correlates with validated hepatic encephalopathy (HE) tests and may predict future overt HE, according to a study published online Sept. 12 in Hepatology.In a two-center prospective cohort study, Patricia P. Bloom, M.D., from the University of Michigan in Ann Arbor, and colleagues examined whether analysis of s

Ryan Stidham, MD, MS, a leading AI researcher, shared his thoughts on how the field has evolved and where it's going, as well as how gastroenterologists will need to adapt.

Only 37 percent of patients with excessive alcohol use (EAU) and a high fibrosis-4 index (FIB-4) are referred to hepatology, according to a study published online Sept. 21 in Alcohol: Clinical &amp; Experimental Research.Kevin Houston, M.D., from Virginia Commonwealth University in Richmond, and colleagues extracted records of patients w

Uptake of colorectal cancer (CRC) screening increased after the 2021 U.S. Preventive Services Task Force (USPSTF) recommendation that all average-risk individuals aged 45 to 49 years should receive screening, according to a study published online Oct. 3 in&nbsp;JAMA Network Open.Sunny Siddique, M.P.H., from the Yale School of Public Heal

In average-risk adults, Cologuard Plus demonstrated sensitivities of 95% for CRC and 43% for advanced precancerous lesions at 94% specificity in the pivotal BLUE-C trial.

Use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with the risk for retained gastric contents and inadequate bowel preparation during endoscopic procedures, according to a research letter published online Oct. 1 in JAMA Network Open.Jason Nasser, M.D., from Cedars-Sinai Medical Center in Los Angeles, and colleagu

Tulisokibart, a tumor necrosis factor-like cytokine 1A monoclonal antibody, is more effective in inducing clinical remission in patients with moderately to severely active ulcerative colitis than placebo, according to a phase 2 study published in the Sept. 26 issue of the&nbsp;New England Journal of Medicine.Bruce E. Sands, M.D., from th

An increase in total cereal intake and total cheese intake may reduce the risk for gastroesophageal reflux disease (GERD), according to a study published online Sept. 6 in the European Journal of Nutrition.Xingwu Liu, M.D., from the First Hospital of China Medical University in Shenyang, and colleagues performed a two-step Mendelian ra

Training physicians in shared decision-making did not significantly improve the rate of older adults receiving their preferred approach to colorectal cancer screening in a randomized controlled trial.

The experimental monoclonal antibody tulisokibart safely induced clinical remission in a phase 2 randomized trial of moderately to severely active ulcerative colitis.

Among patients with Crohn's disease, anti-TNF therapy failed to achieve remission at 3 years, and high drug concentrations early in treatment were linked to greater probability of sustained remission.

While a race-blind algorithm underpredicted and overpredicted CRC risk in Black and White participants, respectively, an algorithm adjusted for race was better calibrated for both groups.

The altered antibody, detectable in blood, may initiate inflammation up to 6 years before symptom onset.

The overall incidence rates for all cancer sites and specific cancer sites returned to prepandemic levels in 2021, according to a study published online Sept. 24 in the Journal of the National Cancer Institute.Nadia Howlader, Ph.D., from the National Cancer Institute in Rockville, Maryland, and colleagues used 2021 incidence data from

A new epigenetic assay is able to stratify patients with Barrett's esophagus according to their probability of neoplastic progression within 5 years, a study found.

In a review of 32 mixed-type human studies, multinational researchers found a growing association between various classes of environmental pollutants and the risk for inflammatory bowel disease.

New approaches to nutrition in dementia, cystic fibrosis, and chronic obstructive pulmonary disease were reviewed at a recent conference.

For people with an eating disorder, electrolyte abnormalities are associated with death and poor physical health outcomes, according to a study published in the October issue of The Lancet Psychiatry.Marco Solmi, M.D., Ph.D., from the University of Ottawa in Ontario, Canada, and colleagues conducted a retrospective population-based co

AI-assisted pathology will enable early, accurate diagnosis of liver disease and offer insights that predict which patients may respond to specific therapies, improving clinical management.

The condition affects millions of people, and the current criteria may erroneously exclude it in certain cases.

More and more research suggests that gut microbiome metabolites could hold the key to treating nearly every disease.

The multitarget stool DNA test was better at detecting advanced serrated colorectal lesions than other stool-based tests, a recent study found.

While the new Shield blood test may motivate more people to get screened for colorectal cancer, it also comes with downsides, experts said.

As quality indicators and benchmarks for colonoscopy increase in coming years, gastroenterologists must think about ways to improve performance across the procedure continuum.

Assessing mucosal impedance via endoscopy could become the go-to method for diagnosing GERD, with high sensitivity and less patient discomfort.

Commonly used fecal immunochemical tests vary in their performance, which has implications for the benefits and cost-effectiveness of FIT-based CRC screening programs.

Research from the University of Michigan suggests that one day a phone app could be able to detect the development of hepatic encephalopathy in patients just by listening to them speak.

A significant proportion of patients developed exocrine pancreatic insufficiency 12 months after a diagnosis of acute pancreatitis, according to a large prospective study.

A new prognostic model can predict and stratify hepatocellular carcinoma (HCC) risk in noncirrhotic adult patients with chronic hepatitis B (CHB), according to a study published online Sept. 17 in the Annals of Internal Medicine.Gi-Ae Kim, M.D., Ph.D., from Kyung Hee University Hospital in Seoul, South Korea, and colleagues developed

For patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a reduced risk for cirrhosis and for cirrhosis complications and mortality, according to a study published online Sept. 16 in JAMA Internal Medicine.Fasiha Kanwal,

The U.S. Food and Drug Administration has approved Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.Tremfya is the first and only dual-acting interleukin-23 inhibitor approved in active ulcerative colitis. It is approved for administration as a 200-mg induction dose intravenously at weeks 0,

Recommendations have been developed to address evaluation and management of chronic constipation, according to updated American Society of Colon and Rectal Surgeons guidelines published in the October issue of Diseases of the Colon &amp; Rectum.Karim Alavi, M.D., M.P.H., from UMass Memorial Medical Center in Worcester, Massachusetts, a

For patients with locally advanced rectal cancer pursuing organ preservation, long-course chemoradiotherapy (LCCRT) is the preferred total neoadjuvant therapy (TNT) regimen, according to a study published online Sept. 11 in the Annals of Oncology to coincide with the European Society for Medical Oncology Congress 2024, being held from Sept.

The Baveno VI criteria could be considered for widespread implementation due to favorable safety and economic factors, the study authors said.

A gastrointestinal-targeted bitter hop extract reduced hunger and food cravings, as well as post-fast ad libitum energy intake, among women undergoing acute fasting for 24 hours.

A history of upper gastrointestinal mucosal damage (MD) is associated with a higher subsequent risk for developing Parkinson disease (PD), according to a study published online Sept. 5 in&nbsp;JAMA Network Open.Jocelyn J. Chang, from Tufts University in Boston, and colleagues evaluated the association between upper endoscopy finding

Two Texas Tech Health El Paso gastroenterology researchers are receiving recognition for their clinical investigation of an electronic capsule that wirelessly relays important information about a patient's gut motor function as it passes through the digestive tract.

In a video posted to Reddit this summer, Lucie Rosenthal's face starts focused and uncertain, looking intently into the camera, before it happens.

The benefits of bariatric surgery on obesity-related cancer and cardiovascular disease seen in younger adults may not translate to older adults, a population-based cohort study concluded.

Whether a fat comes from plants or animals, and what fatty acids it contains, may influence risk for mortality.

ChatGPT was only moderately accurate in answering guideline-based questions regarding the management of severe acute pancreatitis.

Omission of 5-fluorouracil (5-FU) from the first-line FOLFOX, FOLFIRI, and FOLFIRINOX regimens is not associated with reduced survival among patients with advanced colorectal, gastroesophageal, and pancreatic cancers, according to a study published online Sept. 5 in the Journal of the National Comprehensive Cancer Network.Chengwei Pen

The American Society of Colon and Rectal Surgeons (ASCRS) has issued updated guidelines on how to evaluate and manage chronic constipation. The research is published in the journal Diseases of the Colon & Rectum.

For adults with hepatocellular carcinoma or liver metastases, low-dose liver radiotherapy plus best supportive care improve pain compared with best supportive care alone, according to a study published online Sept. 5 in The Lancet Oncology.Laura A. Dawson, M.D., from the Princess Margaret Cancer Centre at the University of Toronto, an

Updated ACG/ASGE task force recommendations outline new quality indicators for colonoscopy, a list that for the first time includes sessile serrated lesion detection rate and adequate bowel prep.

More than 70 percent of patients with stage I pancreatic ductal adenocarcinoma (PDAC) and close to 30 percent with stage II PDAC are upstaged on histopathology, according to a research letter published online Sept. 5 in the Journal of the American Medical Association.Gerardo Perrotta, M.D., from Cedars-Sinai Medical Center in Los Angele

Women with&nbsp;hepatocellular carcinoma (HCC) are less likely to receive a&nbsp;deceased-donor liver transplant (DDLT)&nbsp;and more likely to die while wait-listed than men, according to a study published online Sept. 4 in&nbsp;JAMA Surgery.David C. Cron, M.D., from Massachusetts General Hospital in Boston, and colleagues examined whe

In a clinical practice guideline issued by the American College of Gastroenterology and published in the September issue of the American Journal of Gastroenterology, recommendations are presented for the treatment of patients with Helicobacter pylori (H. pylori) infection.William D. Chey, M.D., from Michigan Medicine i

Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are chronic conditions that significantly impact patients' quality of life. While significant advancements have been made in treatment options, pursuing long-term disease remission remains a challenge.

The procedure has spread, primarily thanks to increasingly loud rumblings in the bowels of Reddit.

In updating their recommendations for the first time in nearly a decade, the ACG/ASGE Task Force highlighted four quality indicators considered a particularly high priority.

More than half of patients with IBD who failed to initially respond to the standard HBV vaccination schedule eventually benefited from enhanced revaccination strategies.

Liver grafts from hepatitis C virus-positive (HCV+) donation after circulatory death (DCD) donors have one-year patient and graft survival comparable with that of donation after brain death (DBD) liver grafts from donors with or without HCV infection, according to a study published online Aug. 22 in&nbsp;Transplantation.Sai Rithin Pu

An overgrowth of gut microorganisms that produce methane could be a cause of severe constipation in many people, a new review finds.

More than 5 billion people globally do not consume enough iodine, vitamin E, and calcium, according to a study published online Aug. 29 in The Lancet Global Health.Simone Passarelli, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues estimated micronutrient intake using a novel approach accounting for t

Fecal immunochemical tests (FITs) have variable sensitivity and specificity for detecting advanced colorectal neoplasia (ACN), according to a study published online Sept. 3 in the Annals of Internal Medicine.Barcey T. Levy, M.D., Ph.D., from the University of Iowa Carver College of Medicine in Iowa City, and colleagues compared the per

A team of Mayo Clinic researchers has developed an innovative computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses and other microorganisms within the digestive system, to provide insights into overall well-being.

Fecal immunochemical tests (FITs) have variable sensitivity and specificity for detecting advanced colorectal neoplasia (ACN), according to a study published online Sept. 3 in the Annals of Internal Medicine.

In the setting of isocaloric eating, time-restricted eating did not reduce weight or improve glucose homeostasis relative to a usual eating pattern, a small randomized controlled trial found.

An online nutrition education program for patients following sleeve gastrectomy attracted substantial interest, primarily among women, and received positive reviews, but more study is needed.

A dietary pattern centered around processed foods was associated with a known microbial signature of CRC and correlated with an elevated risk for its development.

Patients with early-onset colorectal cancer (EO-CRC) living in rural areas have lower five-year survival rates than their urban-dwelling counterparts, according to a research letter published online Aug. 28 in&nbsp;JAMA Network Open.Meng-Han Tsai, Ph.D., from the Georgia Prevention Institute at Augusta University, and colleagues examine

Statin usage in patients with MASLD is associated with a lower long-term risk for all-cause mortality, liver-related events, and progression of liver stiffness.

In patients with abdominal pain and gallstones, a more restrictive approach may avoid unnecessary cholecystectomies, with no difference in five-year outcomes, according to a study published online Aug. 21 in&nbsp;JAMA Surgery.Daan J. Comes, M.D., from Radboud University Medical Centre in Nijmegen, Netherlands, and colleagues evaluated

People with chronic liver disease (CLD) have a higher likelihood of barriers to health care, according to a study recently published in&nbsp;Gastro Hep Advances.Carrie R. Wong, M.D., Ph.D., from the University of California in Los Angeles, and colleagues compared the probability of barriers and recurrent acute care use among persons w

Potential mechanisms and therapeutic targets point the way toward a more personalized approach to IBD management.

Adult patients with inflammatory bowel disease (IBD) and respiratory syncytial virus (RSV) infection have an increased risk for hospitalization, according to a study published online in the August issue of The&nbsp;American Journal of Gastroenterology.Ryan A. Smith, M.D., from University of Wisconsin in Madison, and colleagu

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed a probiotic-based therapeutic that synergistically restores intestinal redox and microbiota homeostasis. This therapeutic effectively relieved inflammation and reduced colonic damage in mouse and non-human primate (NHP) models of colitis. The study is published in Cell Host & Microbe.

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

For salvage for biliary access in patients with benign biliary disease and difficult bile duct cannulation, the endoscopic ultrasound-guided rendezvous technique (EUS-RV) and precut sphincterotomy have similar success rates and comparable, acceptable complication rates, according to a study published online Aug. 27 in the Annals of Internal Medici

Stretching and meditation both help reduce muscle cramp severity for individuals with cirrhosis, according to a study published online June 11 in&nbsp;Liver International.Elliot B. Tapper, M.D., from the University of Michigan in Ann Arbor, and colleagues compared the effectiveness of stretching or meditation for 35 days in 98 patients

Cleveland Clinic–led research identified geographic "hot spots" across the United States where increased colorectal cancer screening is needed to improve outcomes in Hispanic or Latina communities.

Regular use of aspirin was associated with significantly greater reduction in risk for colorectal cancer among adults with less healthy lifestyles, a large observational study found.

Capsule endoscopy and double-balloon enteroscopy identified complications beyond the reach of conventional bidirectional endoscopy in patients with celiac disease who have persistent symptoms.

Guidelines say screening and surveillance can end at age 75, but many people continue to receive colonoscopies well after that time. Is there an optimal time to stop?

: In patients with acute pancreatitis, concomitant chronic liver disease more than doubles the odds of in-hospital mortality and leads to higher rates of complications.

Televisit-delivered outpatient care for inflammatory bowel disease (IBD) is not associated with a higher risk for IBD-related hospitalization, according to a study published in the August issue of The&nbsp;American Journal of Gastroenterology.Shirley Cohen-Mekelburg, M.D., from the VA Center for Clinical Management Research in

ALD's prevalence is increasing in all populations. However, recent data suggest that women, ethnic and racial minority groups, and young adults require special consideration.

Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) can be identified using an index of symptoms, which differs for school-aged children and adolescents, according to a study published online Aug. 21 in the Journal of the American Medical Association.Rachel S. Gross, M.D., from the NYU G

Patients treated with neoadjuvant immune checkpoint inhibitor (ICI)-based therapy for hepatocellular carcinoma (HCC) have higher-risk disease features but achieve outcomes comparable to those undergoing upfront surgery, according to a study published online Aug. 15 in Cancer Research Communications.Mari Nakazawa, M.D., from the Johns

Esoproedict can stratify Barrett esophagus (BE) patients as having a low or high risk for progression, according to a study published online Aug. 14 in the American Journal of Gastroenterology.Sarah E. Laun, Ph.D., from Previse in Baltimore, and colleagues validated Esopredict, a prognostic assay based on DNA methylation levels that s

In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists at Scripps Research have discovered why: a small molecule produced by the worms' intestines during fasting travels to the brain to block a fat-burning signal during this time.

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

Cold snare endoscopic mucosal resection (EMR) may be a safe therapeutic option for selected large colorectal polyps, thanks to a safety profile superior to that of hot EMR.

Using a new classification of steatotic liver disease (SLD) based on the presence of metabolic dysfunction and alcohol consumption, metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD) are significantly associated with the new onset of chronic kidney disease (CKD), according to a study published o

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

Nonstatin cholesterol absorption inhibitors may be associated with a reduced risk for primary liver cancer, whereas bile acid sequestrants may increase that risk.

Non-statin cholesterol absorption inhibitors may be associated with a reduced risk for primary liver cancer, whereas bile acid sequestrants may increase that risk.

The risk for patient death associated with low nurse staffing is only partly alleviated by using temporary staff to fill shortfalls, according to a study published online Aug. 19 in&nbsp;JAMA Network Open.Peter Griffiths, R.N., Ph.D., from the University of Southampton in the United Kingdom, and colleagues explored the association betwe

Cancers of the digestive system mainly include esophageal, gastric, liver, gallbladder, pancreatic, and colorectal cancers. With an estimated 20 million new cases, colorectal cancer is the third-most common cancer and the second leading cause of cancer-related deaths, closely followed by gastric and liver cancers, which are the fifth- and third-leading causes of deaths, respectively.

Perdue Foods has recalled over 167,000 pounds of chicken nuggets and tenders after consumers complained of finding bits of metal in the products.The recall covers select lots of Perdue Breaded Chicken Tenders, Butcher Box Organic Chicken Breast Nuggets and Perdue Simply Smart Organics Breaded Chicken Breast Nuggets.No injuries or adverse

Automated multiorgan computed tomography (CT), including visceral fat, can predict diabetes and associated cardiometabolic conditions, according to a study published online Aug. 6 in Radiology.Yoosoo Chang, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues examined the ability of automate