All articles tagged: Pharmacy

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

Antiviral treatment is underutilized among children and adolescents hospitalized with influenza, according to research published in the Nov. 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Using data from two U.S. influenza surveillance networks, Aaron M. Frutos, Ph.D., from the CDC

For patients with chronic kidney disease (CKD), the risk for emergently treated hypocalcemia with denosumab increases with worsening CKD stage, according to a study published online Nov. 19 in the Annals of Internal Medicine.Steven T. Bird, Ph.D., Pharm.D., from the U.S. Food and Drug Administration in Silver Spring, Maryland, and coll

For patients with immunoglobulin G (IgG)4-related disease, inebilizumab reduces the risk for flares and increases the likelihood of flare-free complete remission, according to a study published online Nov. 14 in the New England Journal of Medicine to coincide with the annual meeting of the American College of Rheumatology, held from Nov. 14 t

Colchicine fails to improve knee pain, function, or size of synovial effusions with painful knee osteoarthritis (OA), according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 14 to 19 in Washington, D.C.Jonathan Samuels, M.D., from NYU Langone in Rye Brook, New York, and colleagues assessed wh

Barriers to widespread access to cancer treatments include excessive cost and lack of affordability, according to a review published online Nov. 18 in Cancer.Arafat H. Tfayli, M.D., from the American University of Beirut Medical Center, and colleagues conducted a systematic review to examine the current state of cancer drug development

Two Wyoming abortion bans, including the first state law to prohibit the use of abortion pills, violate the state's constitution, a judge ruled Monday.In her decision, Judge Melissa Owens, of Teton County District Court, wrote that both a <a href="https://wyoleg.gov/Legislation/2023/SF0109"

Global coverage with measles vaccination declined during the COVID-19 pandemic, and estimated measles cases increased 20 percent worldwide from 2022 to 2023, according to research published in the Nov. 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Anna A. Minta, M.D., from the Worl

Metformin is associated with a lower rate of asthma attacks among people with diabetes, according to a study published online Nov. 18 in&nbsp;JAMA Internal Medicine.Bohee Lee, Ph.D., from Imperial College London, and colleagues estimated the association of metformin and add-on antidiabetic medications (glucagon-like peptide-1 receptor a

Gabapentinoid use is associated with an increased risk for hip fractures, according to a study published online Nov. 13 in&nbsp;JAMA Network Open.Miriam T.Y. Leung, from the Centre for Medicine Use and Safety at Monash University in Melbourne, Australia, and colleagues investigated the association between gabapentinoids and the risk for

For children with achondroplasia, oral infigratinib does not result in major safety signals and yields increased annualized height velocity and z score at a dose of 125 mg, according to a study published online Nov. 18 in the New England Journal of Medicine.Ravi Savarirayan, M.B., B.S., M.D., from Murdoch Children's Research Institute i

Beta-blocker treatment can lead to a modest increase in depressive symptoms among patients who have myocardial infarction with preserved left ventricular ejection fraction (LVEF), according to a study published online Oct. 3 in the European Heart Journal: Acute CardioVascular Care.Philip Leissner, from Uppsala University in Sweden, and

For patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC), chemoradiotherapy (CRT) followed by immunochemotherapy (iCT) and then surgery is promising, according to a study published online Nov. 15 in Clinical Cancer Research.Xin Wang, from the Chinese Academy of Medical Sciences and Peking Union Medical C

For patients with obesity and prediabetes, three years of tirzepatide yields substantial and sustained weight reduction and a reduced risk for progression to type 2 diabetes, according to a study published online Nov. 13 in the New England Journal of Medicine.Ania M. Jastreboff, M.D., Ph.D., from the Yale School of Medicine in New Haven

Patients with venous thromboembolism (VTE) initiating oral anticoagulants have an increased risk for bleeding when using nonsteroidal anti-inflammatory drugs (NSAIDs), according to a study published online Nov. 17 in the European Heart Journal.Søren Riis Petersen, from Aarhus University Hospital in Denmark, and colleagues conducted a na

The U.S. Food and Drug Administration has approved Cobenfy (xanomeline and trospium chloride), a first-in-class muscarinic agonist, for the treatment of schizophrenia in adults.The oral medication represents the first new class of medicine in several decades and selectively targets M1&nbsp;and M4&nbsp;receptors in the bra

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

In the wake of Donald Trump's victory in the presidential election, retailers report that online sales of emergency contraceptives have soared.The spike in purchases of what is also known as the morning-after pill or Plan B suggests women worry the incoming administration might soon limit their access to emergency contraception, <a href="http

The U.S. Food and Drug Administration has approved Emrosi (minocycline hydrochloride) for the treatment of inflammatory rosacea in adults.The extended-release capsules (40 mg) will be available late in the first quarter or early in the second quarter of 2025.The approval was based on positive results from two 16-week phase 3 clinical tri

For patients with ischemic stroke, sodium-glucose cotransporter-2 inhibitors (SGLT-2is) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are associated with reduced mortality, myocardial infarction (MI), and recurrent stroke, according to a study presented at the American Heart Association Scientific Sessions 2024, held from Nov. 16 to 18 in

For patients with nephrolithiasis, sodium-glucose cotransporter-2 (SGLT-2) inhibitor use is associated with a reduction in recurrence, according to a study published online Oct. 30 in The BMJ.Natalie McCormick, Ph.D., from Massachusetts General Hospital in Boston, and colleagues emulated target trials comparing recurrence of nephrolith

Reactogenicity is comparable for simultaneous and sequential administration of mRNA COVID-19 and influenza vaccines, according to a study published online Nov. 6 in JAMA Network Open.Emmanuel B. Walter, M.D., M.P.H., from the Duke University School of Medicine in Durham, North Carolina, and colleagues compared the reactogenicity, safety,

More than a year after its advisory panel unanimously declared the drug phenylephrine to be useless against nasal congestion, the U.S. Food and Drug Administration is proposing that it be removed from common over-the-counter decongestants.Products that in

Expanding access to obesity medications such as glucagon-like peptide 1 (GLP-1) receptor agonists and dual gastric inhibitory polypeptide and GLP-1 receptor agonists could avert 42,000 deaths annually in the United States, according to a study published online Oct. 15 in the Proceedings of the National Academy of Sciences.Abhishek Pand

The head of the company that makes the diabetes and obesity drugs Ozempic and Wegovy has warned that compounded versions of the active ingredient in those medications have now been linked to at least 100 hospitalizations and 10 deaths.“Honestly, I’m quite alarmed by what we see in the U.S. now,” Novo Nordisk President and CEO <a href="https://w

For complete abortion, medication abortion before confirmed intrauterine pregnancy is noninferior to standard, delayed treatment, according to a study published in the Nov. 7 issue of the New England Journal of Medicine.Karin Brandell, M.D., from the Karolinska Institutet in Stockholm, and colleagues conducted a multicenter, noninferi

In election results that showed protecting women's reproductive freedoms matter to a majority of Americans, abortion rights measures passed in seven states and failed in three.Missouri, Arizona, Nevada, Colorado, New York, Maryland and Montana all backed those rights, while such amendments were defeated in Florida, Nebraska and South Dakota, l

Evidence-based smoking cessation treatment within six months of a cancer diagnosis maximizes survival benefit, according to a study published online Oct. 31 in&nbsp;JAMA Oncology.Paul M. Cinciripini, Ph.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues examined the association between time of entry in

In a multisociety clinical practice guidance document, published online Oct. 29 in Surgery for Obesity and Related Diseases, recommendations are presented for the safe use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in the perioperative period.Noting that GLP-1 RAs have revolutionized the care of patients with metabolic dis

The implementation of recreational cannabis legalization (RCL) in California was associated with an increase in prenatal cannabis use, according to a study published online Nov. 1 in&nbsp;JAMA Health Forum.Kelly C. Young-Wolff, Ph.D., from Kaiser Permanente Northern California in Pleasanton, and colleagues assessed whether RCL in Califo

Low-income patients' access to blockbuster weight-loss drugs through Medicaid remains limited, a new KFF analysis has found.Only 13 states currently allow Medicaid to cover treatment of obesity using glucagon-like peptide-1 agonist (GLP-1) medications, researchers discovered.Under the Medicaid system, individual states are allowed to deci

Adults who have received multiple penicillin courses have a modestly lower risk for Parkinson disease (PD), according to a study published in the October issue of Parkinsonism and Related Disorders.Gian Pal, M.D., from the Rutgers-Robert Wood Johnson Medical School in New Brunswick, New Jersey, and colleagues conducted a nested case-cont

In what may be a first for the United States, a regional public health department in Idaho will no longer provide COVID-19 vaccines, following a close vote by its board.“I’m not aware of anything else like this,” said Adriane Casalotti, chief of government and public affairs for the Nati

Drug-related reports of supply chain issues are less likely to result in drug shortages in Canada than in the United States, according to a study published online Oct. 31 in the Journal of the American Medical Association.Mina Tadrous, Pharm.D., Ph.D., from the University of Toronto, and colleagues compared how frequently reports of drug

Countries with COVID-19 pandemic-associated reductions in childhood immunization coverage have not yet recovered, according to research published in the Oct. 31 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Camille E. Jones, Ph.D., from the CDC in Atlanta, and colleagues present trends

Influenza and 2023 to 2024 COVID-19 vaccination coverage is 80.7 and 15.3 percent, respectively, among health care personnel at acute care hospitals and is lower among health care personnel at nursing homes, according to research published in the Oct. 31 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Repo

For patients with type 2 diabetes mellitus, semaglutide is associated with a reduced risk for a first-time Alzheimer disease (AD) diagnosis compared with other antidiabetic medications, according to a study published online Oct. 24 in Alzheimer's &amp; Dementia.William Wang, from the Case Western Reserve University School of Medicine in

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can decrease the risk for developing early-onset colorectal cancer (EO-CRC) in patients with diabetes regardless of weight, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Temitope Olasehinde, M.D., from

For individuals with obesity and knee osteoarthritis, once-weekly semaglutide yields greater reductions in body weight and pain related to knee osteoarthritis than placebo, according to a study published in the Oct. 31 issue of the New England Journal of Medicine.Henning Bliddal, M.D., from the Copenhagen University Hospital at Bispeb

Inavolisib plus palbociclib-fulvestrant yields significantly longer progression-free survival than placebo plus palbociclib-fulvestrant in patients with PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer, according to a study published in the Oct. 3

Injected micronized amnion/chorion bilayer (AC) product significantly reduces time to symptom relief in patients with refractory interstitial cystitis/bladder pain syndrome (IC/BPS), according to a study published online Oct. 23 in&nbsp;International Urology &amp; Nephrology.Kyle O’Hollaren, from Wayne State University School of Medic

Hormone replacement therapy (HRT) is associated with an increased risk for developing irritable bowel syndrome (IBS) in postmenopausal women, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Jacqueline Khalil, D.O., from Case Western Reserve University in

Generic medications reduce the out-of-pocket (OOP) costs for common neurological conditions, apart from multiple sclerosis, for which costs continue to increase, according to a study published online Oct. 30 in Neurology.Amanda V. Gusovsky, Ph.D., M.P.H., from the Wexner Medical Center at The Ohio State University in Columbus, and co

For patients with operative triple-negative breast cancer, a multigene signature can help tailor adjuvant chemotherapy, according to a study published online Oct. 23 in The BMJ.Min He, from Fudan University Shanghai Cancer and Key Laboratory of Breast Cancer, and colleagues conducted a randomized phase 3 trial in seven cancer centers

There are small but important differences in risk for some clinical outcomes associated with rosuvastatin and atorvastatin, according to a study published online Oct. 29 in&nbsp;Annals of Internal Medicine.Shiyu Zhou, M.D., from Southern Medical University in Guangzhou, China, and colleagues compared the real-world effectiveness and

Atrasentan is associated with a significant and clinically meaningful reduction in proteinuria compared with placebo in patients with immunoglobulin A (IgA) nephropathy, according to a study published online Oct. 25 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology,

Absolute concentrations of fentanyl, methamphetamine, and cocaine in urine specimens increased from 2013 to 2023, according to a study published online Oct. 24 in&nbsp;JAMA Network Open.Andrew S. Huhn, Ph.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues analyzed urine drug testing (UDT) results to q

Among privately insured patients, there was a doubling in the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as antiobesity treatment from 2022 to 2023, with a simultaneous 25.6 percent decrease in the rate of metabolic bariatric surgery, according to a research letter published online Oct. 25 in&nbsp;JAMA Network Open.Ke

For patients with asthma, inhaled corticosteroids (ICS) combined with short-acting β agonists (SABA) and ICS combined with the long-acting β agonist formoterol are each associated with reduced asthma exacerbations compared with SABA alone, according to a study published online Oct. 28 in the Journal of the American Medical Association. The st

In a clinical practice guideline (CPG) issued by the U.S. Department of Veterans Affairs and U.S. Department of Defense and published online Oct. 29 in the Annals of Internal Medicine, updated recommendations are presented for the management of migraine and tension-type headache (TTH).Noting that the 2020 U.S. Department of Veterans Af

In a clinical guideline issued by the American Heart Association and American Stroke Association and published online Oct. 21 in Stroke, updated recommendations are presented for the primary prevention of stroke.Cheryl Bushnell, M.D., from Wake Forest University in Winston-Salem, North Carolina, and colleagues conducted a systematic rev

For patients with a history of overt hepatic encephalopathy (OHE), rifaximin monotherapy (MT) results in significantly fewer OHE episodes than lactulose (LAC) MT, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Jasmohan S. Bajaj, M.D., from Virginia Commonw

Empagliflozin continues to offer cardiorenal benefits for up to 12 months after discontinuation among patients with chronic kidney disease at risk for progression, according to a study published online Oct. 25 in the New England Journal of Medicine to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held fro

From 2010 to 2023, there was an increase in prescribing of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and sodium glucose cotransporter 2 (SGLT2) inhibitors among individuals with type 1 diabetes (T1D), according to a research letter published online Oct. 23 in the Journal of the American Medical Association.Piaopiao Li, from

Long-term treatment of adolescents with moderate-to-severe atopic dermatitis (AD) with upadacitinib is safe and effective through 76 weeks, according to a study published online Oct. 23 in&nbsp;JAMA Dermatology.Amy S. Paller, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues evaluated the effi

Delabeling patients with syphilis who believe they are allergic to penicillin is safe, according to a study presented at the annual meeting of the American College of Allergy, Asthma &amp; Immunology, held from Oct. 24 to 28 in Boston.Aiwei Yan, M.D., from the Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues retrospec

Cognitive behavioral therapy (CBT), modafinil, and their combination are equally beneficial for multiple sclerosis fatigue, according to a study published in the November issue of The Lancet Neurology. Tiffany J. Braley, M.D., from the University of Michigan in Ann Arbor, and colleagues conducted a randomized, comparative effectiveness

Many anaphylaxis protocols are incomplete and/or outdated, and there is a need for patient education regarding treatment of anaphylaxis, according to two studies presented at the annual meeting of the American College of Allergy, Asthma &amp; Immunology, held from Oct. 24 to 28 in Boston.Carly Gunderson, D.O., from the Baylor College of Medicine

For patients with opioid use disorder (OUD) and alcohol use disorder (AUD), prescriptions of glucose-dependent insulinotropic polypeptide (GIP) and/or glucagon-like peptide-1 receptor agonists (GLP-1 RA) are associated with lower rates of opioid overdose and alcohol intoxication, according to a study published online Oct. 16 in Addiction.<

Some Americans should get more than one shot of the updated COVID vaccines because their age or certain health conditions make them more vulnerable to severe infections, U.S. health officials advised this week.Six months after their first shot, people 65 and older and those who are immunocompromised should receive a second dose of the&nbsp;vacci

For adults with hereditary angioedema, the in vivo gene-editing therapy NTLA-2002, which is based on clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9, administered as a single dose reduces angioedema attacks, according to a study published online Oct. 24 in the New England Journal of Medicine to

The recommended first age at which Americans should get the pneumococcal vaccine has been lowered from 65 to 50, the U.S. Centers for Disease Control and Prevention announced Wednesday."Lowering the age for pneumococcal vaccination gives more adults the opportunity to protect themselves from pneumococcal disease at the age when risk of infecti

One year of valacyclovir is beneficial for patients with herpes zoster ophthalmicus (HZO), according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Oct. 18 to 21 in Chicago.Elisabeth Cohen, M.D., from the NYU Grossman School of Medicine and NYU Langone Health in New York City, and colleagues con

The U.S. Food and Drug Administration has approved Vyloy (zolbetuximab-clzb) in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma who

A new report shows the number of women getting abortions in the United States has actually increased since the U.S. Supreme Court overturned Roe v. Wade.Since March 2023, the #WeCount report found a small, consistent increase in abortion rates.

For patients receiving mirvetuximab soravtansine (MIRV) treatment for primary gynecologic malignancies, corneal toxicity is not uncommon, but usually resolves, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Oct. 18 to 21 in Chicago.Filippos Vingopoulos, M.D., Ph.D., from Stanford Univers

Artificial expiration dates on eye drops in ophthalmology clinics result in significant waste in terms of medication, plastic, and cost, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Oct. 18 to 21 in Chicago.Noting that eye drops in ophthalmology clinics have artificial expiration dates

The U.S. Food and Drug Administration has approved Vyalev (foscarbidopa and foslevodopa) for adults living with advanced Parkinson disease (PD).Vyalev is the first and only subcutaneous 24-hour continuous infusion of levodopa-based therapy for the treatment of motor fluctuations in advanced PD and allows for personalized dosing throughout the d

Aerobic exercise does not result in differences in objective cognitive function after chemotherapy completion among women with breast cancer, according to a study published online Oct. 21 in Cancer.Jennifer Brunet, Ph.D., from the University of Ottawa in Ontario, Canada, and colleagues examined the effects of an aerobic exercise interv

Patients with inflammatory bowel disease (IBD) continue to experience barriers to health care access and treatment and financial struggles, according to a study published online Oct. 8 in&nbsp;Inflammatory Bowel Diseases.Ariel A. Jordan, M.D., from University of Michigan in Ann Arbor, and colleagues surveyed IBD patients and their careg

Treating hospitalized patients with bloodstream infections with antibiotics for seven days is noninferior to treating for 14 days, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in &nbsp;Los Angeles.Nick Daneman, M.D., and Rob Fowler, M.D., from the University

Preexposure prophylaxis (PrEP) use increased between 2013 and 2023, according to a research letter published online Oct. 14 in the&nbsp;Journal of the American Medical Association.Laura M. Mann, Ph.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues used the IQVIA Real-World Longitudinal Presc

Pembrolizumab plus chemotherapy improves disease-free survival (DFS) in patients with high-risk endometrial cancer after surgery with curative intent, according to a study published online Oct. 16 in the&nbsp;Journal of Clinical Oncology.Brian M. Slomovitz, M.D., from Mount Sinai Medical Center in Miami Beach, and colleagues conducted a

Health insurers would be required to cover the cost of over-the-counter birth control and emergency contraception under new rules proposed by the White House on Monday."Since Roe v. Wade was overturned more than two years ago, Republican elected officials have made clear they want to ban or restrict birth control, defund federal programs that he

Vaccination for influenza, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), and respiratory syncytial virus (RSV) is less likely with an increasing social vulnerability index (SVI) and Black race, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Ange

Annual wasteful spending on discarded lecanemab is anticipated to range between $133 and $336 million, given current vial sizes, according to a research letter published online Oct. 14 in JAMA Internal Medicine.Noting that lecanemab dosing is weight-based and only available in 500- and 200-mg vials, Frank F. Zhou, from the David Geffen

The Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine, licensed in the United States to prevent smallpox and mpox, is well tolerated and seems effective in adolescents, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.Catherine Mary Healy

Implementation of an electronic health record (EHR) order set increases compliance with the recommended duration of prescribed antibiotics for children with acute otitis media (AOM), according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.Joana Dimo, D.

From 2013 to 2021, there was a decline in benzodiazepine initiation for post-acute ischemic stroke (AIS), according to a study published online Oct. 17 in Stroke.Victor Lomachinsky Torres, M.D., from Massachusetts General Hospital in Boston, and colleagues analyzed a 20 percent sample of U.S. Medicare claims from April 1, 2013, to Sep

For patients with acute ischemic stroke (AIS), tenecteplase (TNK) has improved functional outcome and reduced disability and similar safety to alteplase (tissue plasminogen activator [TPA]), according to a study published online Oct. 16 in Neurology.Lina Palaiodimou, M.D., Ph.D., from the National and Kapodistrian University of Athens

Paternal metformin use during the period of sperm development is not associated with an increased risk for congenital malformations in offspring, according to a study published online Oct. 16 in The BMJ.Lin-Chieh Meng, from the National Taiwan University, and colleagues examined the association between paternal metformin use and the r

For patients with stage III or IV Hodgkin lymphoma, nivolumab with doxorubicin, vinblastine, and dacarbazine (N+AVD) yields longer progression-free survival (PFS) than brentuximab vedotin with doxorubicin, vinblastine, and dacarbazine (BV+AVD), according to a study published online Oct. 16 in the New England Journal of Medicine.Alex

Patients aged 10 to 17 years who are prescribed glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are more likely to have comorbid type 2 diabetes, high body mass index, and a previous metformin prescription, according to a research letter published online Oct. 16 in&nbsp;JAMA Network Open.Margaret G. Miller, from Case Western Re

COVID-19 vaccination is associated with a reduced risk for most cardiovascular events, but with slightly increased risks of extrasystoles and transient ischemic attack, as well as myocarditis and pericarditis after mRNA vaccination, according to a study published online Sept. 30 in the European Heart Journal.Yiyi Xu, Ph.D., from the

The U.S. Food and Drug Administration approved Itovebi (inavolisib), in combination with palbociclib (Ibrance) and fulvestrant, for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer.Th

For individuals with heart failure with reduced ejection fraction (HFrEF), substantial mortality benefits would result from optimal use of guideline-directed medical therapy (GDMT), according to a study published online Oct. 2 in JAMA Cardiology.Amber B. Tang, M.D., from the University of California Los Angeles, and colleagues examin

The rate of layperson-administered naloxone (LAN) increased from 2020 to 2022, according to a study published online Oct. 14 in&nbsp;JAMA Network Open.Christopher B. Gage, from Ohio State University in Columbus, and colleagues assessed whether the frequency of LAN in conjunction with emergency medical services (EMS) activations chang

For adolescents with obesity, glucagon-like peptide 1 receptor agonist (GLP1-RA) treatment is associated with a reduced risk for suicidal ideation or attempts, according to a study published online Oct. 14 in JAMA Pediatrics.Liya Kerem, M.D., and Joshua Stokar, M.D., from Hadassah University Medical Center in Israel, examined the incid

For adolescents with obesity, glucagon-like peptide 1 receptor agonist (GLP1-RA) treatment is associated with a reduced risk for suicidal ideation or attempts, according to a study published online Oct. 14 in JAMA Pediatrics.Liya Kerem, M.D., and Joshua Stokar, M.D., from Hadassah University Medical Center in Israel, examined the incid

The American Thoracic Society is providing tips to help hospitals mitigate impacts on intravenous (IV) fluid supply resulting from manufacturing disruptions due to recent hurricanes.W. Graham Carlos, M.D., and colleagues provide guidance on how health care systems facing shortages of these fluids may conserve fluids and address the shortages.</

The American Thoracic Society is providing tips to help hospitals mitigate impacts on intravenous (IV) fluid supply resulting from manufacturing disruptions due to recent hurricanes.W. Graham Carlos, M.D., and colleagues provide guidance on how health care systems facing shortages of these fluids may conserve fluids and address the shortages.</

The U.S. Food and Drug Administration (FDA) approved Hympavzi (marstacimab-hncq) for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients aged 12 years and older with hemophilia A without factor VIII inhibitors or hemophilia B without factor IX inhibitors.Unlike other drugs that replace a c

Lithium aspartate is not effective for neurologic post-COVID-19 condition (PCC) symptoms of fatigue and cognitive dysfunction, according to a study published online Oct. 2 in JAMA Network Open.Thomas Guttuso Jr., M.D., from the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo in Williamsville, New York, an

An estimated 15.5 million U.S adults had a current diagnosis of attention-deficit/hyperactivity disorder (ADHD) in 2023, according to research published in the Oct. 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Brooke S. Staley, Ph.D., from the CDC in Atlanta, and colleagues estim

Pharmacists may continue making compounded versions of the weight-loss medication tirzepatide while the U.S. Food and Drug Administration revisits its Oct. 2 decision to remove the medicine from a national drug shortage list.What prompted the FDA to reconsider its <a href="https://www.fda.gov/drugs/drug-safety-and-availability/fda-clarifies-pol

For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association.Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital -- Herlev a

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

Potential benzene exposure occurs as a result of benzoyl peroxide (BPO) drug product use, according to a study published online Oct. 7 in the Journal of Investigative Dermatology.The carcinogen benzene is a degradation product of BPO and has been reported to form when BPO drug products are incubated at body temperature and elevated temp

For boys with early-stage cerebral adrenoleukodystrophy and evidence of active inflammation, lentiviral elivaldogene autotemcel (eli-cel) gene therapy offers lasting benefits, according to a study published in the Oct. 10 issue of the New England Journal of Medicine.Florian Eichler, M.D., from Massachusetts General Hospital and Harvard

Across countries, there are considerable disparities in the availability and timeliness of availability of new cancer drugs, according to a study published online Oct. 8 in BMJ Global Health.Meng Li, Ph.D., from Tufts Medical Center in Boston, and colleagues examined the availability and timeliness of availability of new cancer drugs

Youth antidepressant warnings had a detrimental unintended effect: significant reductions in mental health care, according to a report published in the October issue of Health Affairs.Noting that since 2003 the U.S. Food and Drug Administration has warned that antidepressants may be associated with suicidal thoughts and behaviors amon

Improvements in nondystrophic myotonias symptoms are similar for lamotrigine and mexiletine, according to a study published in the October issue of&nbsp;The Lancet Neurology.Vinojini Vivekanandam, Ph.D., from the Centre for Neuromuscular Disorders at the National Hospital for Neurology and Neurosurgery in London, and colleagues random

Dronabinol is safe and effective for the treatment of Alzheimer disease with agitation (Agit-AD), according to a study presented at the annual meeting of the International Psychogeriatric Association, held from Sept. 25 to 27 in Buenos Aires, Argentina.Paul Rosenberg, M.D., from Johns Hopkins University School of Medicine in Baltimore, and col

Nine in 10 pediatric opioid exposures occur unintentionally in the home, according to a brief report published online Aug. 14 in The Journal of Pediatrics.Perry E. Rosen, from the New Jersey Poison Information and Education System in Newark, and colleagues analyzed 230 pediatric opioid exposures (among children aged 1 month through 6

Social risk factors are associated with decreased odds of receiving preventive services such as mammograms, Papanicolaou (Pap) tests, flu or pneumococcal vaccines, and colonoscopies, according to a study published online Oct. 4 in&nbsp;JAMA Network Open.Tamara Schroeder, M.D., from the University of California, Davis, and colleagues exa

Ciltacabtagene autoleucel (cilta-cel) CAR T-cell therapy for relapsed/refractory multiple myeloma (RRMM) results in a deep and durable response, according to a study published online Oct. 4 in&nbsp;Blood.Surbhi Sidana, M.D., from Stanford University in California, and colleagues reported outcomes with cilta-cel in the standard-of-care s

Lack of knowledge of antibiotic risks contributes to primary care patients' expectations of antibiotics for common symptoms, according to a study published online in the September/October issue of the&nbsp;Annals of Family Medicine.Lindsey A. Laytner, Ph.D., from the Baylor College of Medicine in Houston, and colleagues conducted a surv

For people with HIV (PWH) with low-to-moderate atherosclerotic cardiovascular disease (ASCVD) risk, metabolic risk factors contribute to new-onset diabetes mellitus (DM) among those treated with pitavastatin or placebo, according to a study published online Oct. 8 in the Annals of Internal Medicine.Kathleen V. Fitch, from Massachusetts G

A one-dose human papillomavirus (HPV) vaccination program is projected to prevent a similar number of cervical cancers as a two-dose program, according to a study published online Oct. 7 in CMAJ, the journal of the Canadian Medical Association.Mélanie Drolet, Ph.D., from the Université Laval in Québec City, and colleagues used an individ

For patients with hidradenitis suppurativa (HS), bimekizumab is safe and efficacious over two years, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Christos C. Zouboulis, from the European Hidradenitis Suppurativa Foundation in Dessau, Germany, and

For patients with relapsed/refractory large B-cell lymphoma (LBCL), the autologous, CD19-directed, 4-1BB chimeric antigen receptor T-cell product, lisocabtagene maraleucel (liso-cel), is safe for outpatients and inpatients and is efficacious, according to a study published online Sept. 30 in Blood Advances.Yuliya Linhares, M.D., from the

Dupilumab improves health-related quality of life (HRQoL) in patients with chronic obstructive pulmonary disease (COPD) and type 2 inflammation, according to a study presented at CHEST 2024, the annual meeting of the American College of Chest Physicians, held from Oct. 6 to 9 in Boston.&nbsp;Surya P. Bhatt, M.D., from the University of Alabama at

Immunity against mpox may be waning for those vaccinated with the modified vaccinia Ankara-Bavarian Nordic (MVA-BN; Jynneos) vaccine, according to a research letter published online Oct. 3 in the Journal of the American Medical Association.Ai-ris Y. Collier, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues as

For patients with moderate-to-severe atopic dermatitis (AD), lebrikizumab has long-term efficacy, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Diamant Thaçi, Ph.D., from University Lübeck in Germany, and colleagues reported long-term efficacy and

Use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with the risk for retained gastric contents and inadequate bowel preparation during endoscopic procedures, according to a research letter published online Oct. 1 in JAMA Network Open.Jason Nasser, M.D., from Cedars-Sinai Medical Center in Los Angeles, and colleagu

Tulisokibart, a tumor necrosis factor-like cytokine 1A monoclonal antibody, is more effective in inducing clinical remission in patients with moderately to severely active ulcerative colitis than placebo, according to a phase 2 study published in the Sept. 26 issue of the&nbsp;New England Journal of Medicine.Bruce E. Sands, M.D., from th

Counterfeit medications from online pharmacies pose significant risks to patients, including overdose and death, according to a warning issued by the U.S. Centers for Disease Control and Prevention.The warning follows a federal indictment announced last week again

Rheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a study published online Aug. 6 in&nbsp;ACR Open Rheumatology.Yinan Huang, Ph.D., from the University of Mississippi in Oxford, and colleagues estimated the economic and humanistic burden of RA among

In yet another sign that childhood vaccinations can't be taken for granted, new government data show that a record number of kindergartners were exempted from the required shots during the last school year.That leaves more than 125,000 new students without the protection of at least one childhood vaccine, even as measles vaccination rates among

Olanzapine may be better than prochlorperazine for reducing refractory nausea in patients with breast cancer starting a high/moderate emetogenic chemotherapy regimen, according to a study presented at the American Society of Clinical Oncology annual Quality Care Symposium, held from Sept. 27 to 28 in San Francisco.&nbsp;Luke Joseph Peppone, Ph

Higher doses of buprenorphine for patients with opioid use disorder (OUD) are associated with lower acute care utilization, according to a study published online Sept. 25 in&nbsp;JAMA Network Open.Sarah Axeen, Ph.D., from the University of Southern California in Los Angeles, and colleagues examined the association between higher bupre

Screening pregnant women during their first trimester with a target ferritin concentration of &gt;60 μg/L may identify those at risk for iron deficiency later in pregnancy, according to a study published online Sept. 26 in the&nbsp;American Journal of Clinical Nutrition.Elaine K. McCarthy, Ph.D., from University College Cork in Irelan

The U.S. Food and Drug Administration has approved Dupixent (dupilumab) as an add-on maintenance treatment for adults with inadequately controlled chronic obstructive pulmonary disease (COPD) and an eosinophilic phenotype.The approval was based on results from two pivotal phase 3 trials (BOREAS and NOTUS) that evaluated Dupixent (468 and 470 par

The 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presented at the American Society of Clinical Oncology annual Quality Care Symposium, held from Sept. 27 to 28 in San Francisco.Puneeth Indurlal, M.D., from the U.S. Onco

The U.S. Food and Drug Administration has approved Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, in combination with the enzyme inhibitor miglustat, is approved to treat neurological symptoms associated with NPC in adults and children aged 2 years and older. The approval received pr

In a clinical practice guideline issued by the American Academy of Pediatrics and published online Sept. 30 in Pediatrics, recommendations are presented for opioid prescribing for acute pain management in children and adolescents in outpatient settings.Scott E. Hadland, M.D., M.P.H., from Harvard Medical School in Boston, and colleague

Long-term treatment with finerenone is estimated to extend event-free survival among people with heart failure with mildly reduced or preserved ejection fraction, according to a brief report published online Sept. 27 in JAMA Cardiology to coincide with the annual meeting of the Heart Failure Society of America, held virtually from Sept. 27 to

Measles cases in England are consistent with the waning of vaccine-induced immunity, according to a study published online Sept. 26 in The Lancet Public Health.Alexis Robert, Ph.D., from the London School of Hygiene &amp; Tropical Medicine, and colleagues examined whether measles dynamics observed in England between 2010 and 2019 were

From 1999 to 2020, there was a decrease in menopausal hormone therapy (MHT) use among postmenopausal women, according to a study published online Sept. 27 in JAMA Health Forum.Lin Yang, Ph.D., from Cancer Care Alberta in Calgary, Canada, and colleagues examined trends in and correlates of MHT use among postmenopausal women in the Unite

In the 2023 to 2024 respiratory syncytial virus (RSV) season, more than half of infants were protected by maternal RSV vaccine, nirsevimab, or both, according to research published in the Sep. 26 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Hilda Razzaghi, Ph.D., from the CDC in Atl

For patients with obesity, type 2 diabetes, and estimated glomerular filtration rate (eGFR) 20 to 60 mL/min/1.73 m2, metabolic surgery is associated with a lower risk for progression of kidney impairment compared with glucagon-like peptide-1 receptor agonist (GLP-1RA) treatment, according to a study published in the September issue of the <

Reducing or preventing paramagnetic rim lesions (PRLs) could significantly slow multiple sclerosis (MS) progression, according to a study presented at the annual meeting of the American Neurological Association, held Sept. 14 to 17 in Orlando, Florida.Jack Reeves, Ph.D., from State University of New York at Buffalo, and colleagues assessed the

For infants and young children hospitalized with respiratory syncytial virus (RSV) infection, ziresovir reduces signs and symptoms of bronchiolitis, according to a study published in the Sept. 26 issue of the New England Journal of Medicine.Shunying Zhao, M.D., Ph.D., from Beijing Children's Hospital, and colleagues enrolled participan

The first new type of medication in decades to help fight against schizophrenia was approved on Thursday by the U.S. Food and Drug Administration.Cobenfy (xanomeline/trospium chloride) could bring patients what they've long hoped for: A means of easing the hallucinations and "voices" that disrupt their lives without the weight gain and sluggish

Children born in 2020 to 2021 had lower coverage with nearly all childhood vaccines recommended by age 24 months than those born in 2018 and 2019, according to research published in the Sep. 26 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Holly A. Hill, M.D., Ph.D., from the CDC i

The free COVID-19 tests promised by the U.S. government are now available."U.S. households will be eligible to order four free COVID-19 tests at COVIDTests.gov," according to the U.S. Department of Health and Human Services. "The COVID-19 tests will detect current COVID-19 variants and can be used through the end of the year."More than

The U.S. Food and Drug Administration has approved Ocrevus Zunovo (ocrelizumab and hyaluronidase-ocsq) as the first and only twice-a-year, 10-minute subcutaneous injection for people with relapsing and progressive multiple sclerosis (MS).The injection is administered by a health care professional. Patients are given premedications at least 30

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective signs of inflammation, and adults with active ankylosing spondylitis (AS).Bimzelx selectively inhibits two key cyt

For patients with primary progressive multiple sclerosis (PPMS), the time to confirmed disability progression (CDP) does not differ for those who are anti-CD20-treated and untreated, according to a study published online Sept. 25 in Neurology.Marion Hay, M.D., from Rennes University Hospital in France, and colleagues analyzed CDP in

The U.S. government is offering another round of free COVID-19 tests, which will be available by the end of September."U.S. households will be eligible to order four free COVID-19 tests at COVIDTests.gov," according to the U.S. Department of Health and Human Services. "The COVID-19 tests will detect current COVID-19 variants and can be used

For patients with type 2 diabetes (T2D) and opioid use disorder (OUD), semaglutide is associated with a significantly lower risk for opioid overdose compared with other antidiabetic medications, according to a research letter published online Sept. 25 in JAMA Network Open.William Wang, from the Case Western Reserve University School

Early adoption of the direct oral anticoagulant (DOAC) population management dashboard, the purpose of which includes pharmacist review and correction of off-label dosing prescriptions, is associated with reduced rates of off-label DOAC dosing prescription and reduced bleeding, according to a study published online Sept. 9 in the Journal of the

For patients with obesity, the addition of semaglutide to standard hidradenitis suppurativa (HS) treatments yields improvement in quality of life and a reduction in flares, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Daniel Lyons, M.D., fro

Most Americans don’t plan to get vaccinated against the flu or COVID-19 this season, a new survey has found.Fewer than two in five U.S. adults (38%) say they will definitely get a flu jab, and only one in four (26%) say they’ll get the updated COVID v

During a tense hearing before a Senate committee on Tuesday, Novo Nordisk CEO Lars Fruergaard Jørgensen faced tough questions over the company's high prices for its blockbuster drugs Ozempic and Wegovy.While testifying before the Senate Commit

Few U.S. jails offer medications for opioid use disorder (MOUD), according to a study published online Sept. 24 in JAMA Network Open.Elizabeth Flanagan Balawajder, M.P.H., from NORC at the University of Chicago, and colleagues examined the prevalence of MOUD in U.S. jails and the association of jail- and county-level factors with MOUD

A considerable proportion of U.S. adults has absolute and functional iron deficiency, according to a study published online Sept. 24 in JAMA Network Open.Yahya M.K. Tawfik, Pharm.D., from Brigham and Women's Hospital in Boston, and colleagues conducted a cross-sectional study analyzing data from the National Health and Nutritional Exa

Long-term use of skeletal muscle relaxants (SMRs) for chronic pain is only effective for certain conditions, such as painful spasms, painful cramps, and neck pain, according to a review published online Sept. 19 in&nbsp;JAMA Network Open.Benjamin J. Oldfield, M.D., from the Yale School of Medicine in New Haven, Connecticut, and collea

For adults with symptomatic lumbar disc herniation, unilateral biportal endoscopic (UBE) microdiscectomy is associated with longer operating times and with lower pain medication consumption in the early postoperative period compared with tubular lumbar microdiscectomy, according to a study published online Sept. 19 in Blood.Charla Fis

All active interventions show superior efficacy to placebo for freedom from pain, and most do for sustained pain freedom, for the acute treatment of migraine among adults, according to a review published online Sept. 18 in The BMJ.William K. Karlsson, from the Danish Headache Centre&nbsp;at Copenhagen University Hospital-Rigshospitalet

For patients with hereditary hemorrhagic telangiectasia (HHT), pomalidomide yields a significant reduction in epistaxis severity, according to a study published in the Sept. 19 issue of the New England Journal of Medicine.Hanny Al-Samkari, M.D., from Massachusetts General Hospital in Boston, and colleagues conducted a randomized, place

For patients with recurrent or refractory graft-versus-host disease (GVHD), the colony-stimulating factor 1 receptor (CSF1R)-blocking antibody axatilimab results in a high incidence of overall response, according to a study published in the Sept. 19 issue of the New England Journal of Medicine.Daniel Wolff, M.D., from University Hospit

Limited data indicate that paternal exposure to antiseizure medications (ASMs) at conception is unlikely to pose any major risk for adverse outcomes for offspring, according to a review published online Sept. 17 in the Journal of Neurology, Neurosurgery &amp; Psychiatry.Eliza Honybun, from the University of Melbourne in Australia, and

Influenza vaccination in successive pregnancies is not associated with increased risk for prespecified adverse perinatal outcomes, according to a study published online Sept. 19 in JAMA Network Open.Darios Getahun, M.D., Ph.D., M.P.H., from Kaiser Permanente Southern California in Pasadena, and colleagues conducted a retrospective coho

On Friday, the U.S. Food and Drug Administration approved the FluMist nasal vaccine for self-administration at home.It is a "new option for receiving a safe and effective seasonal influenza vaccine potentially with greater convenience, flexibility, and accessibility for individuals and families," Peter Marks, M.D., director of the FDA Center fo

From 1990 to 2021, the burden of antimicrobial resistance (AMR) decreased for those younger than 5 years and increased for those older than 70 years, according to a study published online Sept. 16 in The Lancet.Mohsen Naghavi and colleagues from the GBD 2021 Antimicrobial Resistance Collaborators estimated all-age and age-specific deat

A mailed knowledge mobilization and behavior change intervention can reduce the use of sedatives and improve sleep outcomes in older adults with insomnia, according to a study published online Sept. 18 in&nbsp;JAMA Psychiatry.David M. Gardner, Pharm.D., from Dalhousie University in Halifax, Nova Scotia, Canada, and colleagues compared

For patients with metastatic renal cell carcinoma (mRCC) and progression during or after one to two prior lines of therapy, including one immune checkpoint inhibitor (ICI), tivozanib has efficacy, according to a study published online Sept. 13 in The Lancet to coincide with the annual meeting of the European Society for Medical Oncology, held

Disease-free survival is significantly longer with adjuvant pembrolizumab than observation among patients with high-risk muscle-invasive urothelial carcinoma after radical surgery, according to a study published online Sept. 18 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncol

Controversial fentanyl lollipops and similar products will no longer be made by drug makers, the U.S. Food and Drug Administration has announced.Known as TIRF medications, these products contain fentanyl and are used to manage breakthrough pain in cancer patients who have become tolerant to around-the-clock opioid therapy, the FDA said in a <a

Whooping cough cases are climbing at the fastest pace in years as students across America return to school, U.S. health officials reported Thursday.In figures&nbsp;published by the U.S. Centers for Disease Control and Prevention, a total of 291 cases were reported

Among military children, there has been an improvement in vaccine completion and timeliness, but the risk for noncompletion is higher among children born to younger parents and those with a well-child care location change, according to a study published online Sept. 19 in Pediatrics.Celeste J. Romano, from the Naval Health Research C

For patients with early-stage triple-negative breast cancer, neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab yields a significant improvement in overall survival compared with neoadjuvant chemotherapy alone, according to a study published online Sept. 15 in the New England Journal of Medicine to coincide with

After severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, prevalent metformin use is associated with a slightly lower incidence of death or postacute sequalae of SARS-CoV-2 (PASC), according to a study published online Sept. 17 in Diabetes Care.Steven G. Johnson, Ph.D., from the University of Minnesota in Minneapo

COVID-19 vaccine-associated myocarditis (C-VAM) has a mild initial clinical course, but myocardial injury is common, according to a study published online in the October issue of eClinicalMedicine.Supriya S. Jain, M.D., from New York Medical College-Maria Fareri Children's Hospital at Westchester Medical Center in Valhalla, and colle

For patients with limited-stage small cell lung cancer, adjuvant therapy with durvalumab leads to significantly longer overall and progression-free survival, according to a study published online Sept. 13 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from Sept.

For patients with advanced melanoma, there is a survival benefit for nivolumab plus ipilimumab and for nivolumab monotherapy compared with ipilimumab monotherapy, according to a study published online Sept. 15 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from S

The U.S. Food and Drug Administration has approved Ebglyss (lebrikizumab-lbkz) for adults and children aged 12 years and older with moderate-to-severe atopic dermatitis.The targeted interleukin-13 inhibitor is administered via a 250-mg/2 mL injection with or without topical corticosteroids in patients with atopic dermatitis not well controll

Monthly use of erenumab injections (140 mg) is safe and effective in achieving medication overuse headache (MOH) remission in patients with nonopioid chronic migraine (CM) and MOH, according to a study published online Sept. 16 in JAMA Neurology.Stewart J. Tepper, M.D., from the New England Institute for Neurology and Headache in St

There are discrepancies between preferred and actual sources of contraceptive information for U.S. adolescents and young adults (AYA), according to a research letter published online Sept. 13 in&nbsp;JAMA Network Open.Elizabeth Pleasants, Dr.P.H., from the University of California, Berkeley, and colleagues examined AYAs’ preferred a

Women with early-stage breast cancer may now take Kisqali, a medication already approved for advanced disease, following the U.S. Food and Drug Administration's expanded approval of the treatment, drug maker Novartis announced Tuesday.“The FDA approval of Kisqali for this early breast cancer p

Wegovy, Zepbound and other cutting-edge weight-loss drugs can be tough to get these days.They’re in short supply, and often too expensive to afford without insurance coverage.Because of these barriers, many people are doing an end-run around t

Among privately insured women, diagnoses of postpartum anxiety and depression did not increase following onset of the COVID-19 pandemic, but there was an increase in the proportion of women filling a benzodiazepine prescription, according to a study published online June 24 in the Archives of Women's Mental Health.Grace Bagwell Adams,

For postoperative patients with breast cancer, the duration of aromatase inhibitor (AI) treatment is not associated with the risk for coronary artery calcium (CAC), according to a study published online Sept. 17 in the Canadian Journal of Cardiology.Yu Hiasa, M.D., from the Ehime University Graduate School of Medicine in Toon, Japan,