All articles tagged: Rheumatology

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

Using home spirometry for the management of systemic sclerosis–associated ILD can enhance the ability to detect pulmonary decline early, leading to better patient care and outcomes.

Early implementation of treatment with biologic or targeted synthetic DMARDs after methotrexate failure did not prevent the development of difficult-to-treat RA in patients with early RA.

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

For patients with immunoglobulin G (IgG)4-related disease, inebilizumab reduces the risk for flares and increases the likelihood of flare-free complete remission, according to a study published online Nov. 14 in the New England Journal of Medicine to coincide with the annual meeting of the American College of Rheumatology, held from Nov. 14 t

Colchicine fails to improve knee pain, function, or size of synovial effusions with painful knee osteoarthritis (OA), according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 14 to 19 in Washington, D.C.Jonathan Samuels, M.D., from NYU Langone in Rye Brook, New York, and colleagues assessed wh

Real-world data show reduction in use of urate-lowering therapy among people with type 2 diabetes using SGLT2 inhibitors.

Most patients with rheumatoid arthritis or spondyloarthritis had significant antibody responses to COVID vaccine boosters, whether or not their immunomodulatory medications were held.

More than half the women in the treat-to-target group conceived within 3 months vs a median of 6.5 months for those in the historical comparison group.

The sFlt-1/PlGF ratio did not effectively gauge future preeclampsia risk in pregnant patients with SLE and proteinuria.

Researchers have identified separate gut bacteria species that can metabolize purines and urate, suggesting that microbial pathways might be leveraged through probiotics to reduce hyperuricemia.

Guidance particularly addresses the value of ultrasound in patient-provider shared decision-making in management of care.

Patients with GPA completely weaned off glucocorticoids were four times as likely to flare compared with those kept on a low dose, though these flares were minor.

Substantial improvements in ultrasound technology and expanded use of it have necessitated an update of the 2012 recommendations.

Dramatic study results point to the potential for a steroid-sparing option for patients with the underrecognized multiorgan condition.

Dramatic study results point to the potential for a steroid-sparing option for patients with the underrecognized multiorgan condition.

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

At-risk individuals who progress to rheumatoid arthritis (RA) have a distinctive gut microbial composition, according to a study published online Nov. 7 in the Annals of the Rheumatic Diseases.Christopher M. Rooney, from the University of Leeds in the United Kingdom, and colleagues examined structural, functional, and temporal changes

A large cross-sectional study revealed that late-onset axial spondyloarthritis diagnosed after 45 years of age may represent a distinct phenotype from early-onset axial spondyloarthritis.

Children with antineutrophil cytoplasmic antibody–associated vasculitis had similar remissions rates with rituximab and cyclophosphamide in an international registry-based study.

COVID-19 is associated with long-term risk for autoimmune and autoinflammatory connective tissue disorders, according to a study published online Nov. 6 in JAMA Dermatology.Yeon-Woo Heo, M.D., from the Yonsei University Wonju College of Medicine in South Korea, and colleagues conducted a retrospective cohort study to examine the long-ter

Alterations in the gut microbiome began as early as 10 months before the onset of RA in anticyclic citrullinated protein–positive individuals at a risk of developing the condition, a study found.

Both infliximab and adalimumab were found to be effective in achieving remission and enhancing quality of life while having a high level of tolerability in patients with mucocutaneous Behçet syndrome.

Medscape Medical News spoke with the ACR’s Rebecca L. Manno, MD, on updates to this year’s program and some highlights at the upcoming meeting.

Sedentary behavior (SB) is negatively associated and light physical activity (PA) is positively associated with vascular parameters among postmenopausal women with rheumatoid arthritis (RA), according to a study published online Nov. 1 in the American Journal of Physiology: Heart and Circulatory Physiology.Kamila Meireles, from the Univ

There is a bidirectional association for rheumatoid arthritis (RA) and interstitial lung disease (ILD), according to a study published online Oct. 12 in the Journal of Clinical Medicine.Bo-Guen Kim, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues examined the bidirectional relationship

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

Patients with seropositive rheumatoid arthritis (RA) with moderate and extreme anxiety/depression have mean health-related quality-of-life (HRQoL) losses, regardless of pain and discomfort, according to a study published online Oct. 30 in Clinical Rheumatology.Diego Fernando Rojas‑Gualdrón, from the Universidad CES in Medellín, Colombia,

Data from recent studies suggested improved risk stratification and understanding of disease pathogenesis are key in identifying more effective medical interventions.

Many people with rheumatologic diseases try supplements for symptom relief. Here’s what you need to know about some common picks.

A recent cross-sectional survey showed that a considerable number of patients with rheumatic diseases switched to medical cannabis for better management of disease symptoms.

Intravenous methylprednisolone is not significantly beneficial vs oral glucocorticoids in improving visual acuity or survival in patients with giant cell arteritis, and it increases diabetes risk.

An analysis of a large population of commercially insured children with juvenile idiopathic arthritis in the US showed an increasing popularity of more targeted therapies over the past two decades.

Greater improvement in patient-reported hip pain and function at 6 months was achieved with total hip replacement than resistance training in the PROHIP trial.

The journal will be part of a new partnership with Elsevier beginning in January 2025.

Allogeneic bone marrow–derived mesenchymal stromal cells were safe but did not demonstrate efficacy in treating intervertebral disc degeneration in patients with chronic low back pain.

The long-acting formulation of fluticasone propionate utilizing extended-release technology may offer a longer duration of pain relief than vehicle control in patients with knee osteoarthritis.

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

Tracking patient response to DMARD therapy has the potential to improve remission, but multiple barriers must be overcome before it’s widely adopted.

Patients with early rheumatoid arthritis (RA) have a high incidence of prevalent and incident hypertension, according to a study published online in the August issue of&nbsp;Rheumatology: Advances in Practice.Brook Hadwen, from the University of Western Ontario in London, Canada, and colleagues used data from the Canadian Early Arthrit

More than 90% of patients with PsA who received guselkumab every 8 weeks in the DISCOVER-2 trial maintained minimal clinically important improvement in joint symptoms through week 52.

JAK inhibitors were found to be either marginally more effective or as effective as biologic DMARDs in reducing pain in patients with rheumatoid arthritis in clinical practice.

Patients with abnormal small bowel transit in systemic sclerosis were more likely to be men and have severe cardiac involvement, higher mortality, and fewer sicca symptoms.

The drug is approved for multiple inflammatory conditions and is expected to launch in the first half of 2025.

Individuals at a high genetic risk for gout faced a significantly higher risk for cardiovascular disease than those at a lower genetic risk and would benefit from adhering to a healthy lifestyle.

In patients with axial spondyloarthritis and a history of cardiovascular events, recurrent cardiovascular events were frequent, but exposure to a TNF inhibitor reduced the risk for these events.

Monitoring and supplementing maternal 25(OH) vitamin D levels in patients with lupus within the 40-59 ng/mL range are crucial while preventing excessive supplementation, this study suggested.

For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association.Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital -- Herlev a

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

Only 13.4% immunocompromised adult US veterans younger than 50 years received the recombinant zoster vaccine by mid-2023, which reflected a lag in the adoption of revised national recommendations.

Patients with rheumatoid arthritis (RA) undergoing standard-of-care treatment frequently have persisting pain, according to a study published online Sept. 30 in the Annals of the Rheumatic Diseases.Christoph Baerwald, M.D., Ph.D., from the University Hospital Leipzig in Germany, and colleagues conducted a prospective multicenter study

For patients with rheumatoid arthritis (RA), urine albumin-to-creatinine ratio (ACR) is an independent risk factor indicating prognosis, according to a study published online Sept. 18 in Frontiers in Immunology.Zexuan Bin, from The Second Hospital of Shanxi Medical University in Taiyuan, China, and colleagues used 2009 to 2018 data fr

Age-related macular degeneration (AMD) is associated with a higher risk for rheumatoid arthritis (RA), according to a study published online Sept. 9 in&nbsp;Scientific Reports.Je Moon Yoon, from Sungkyunkwan University in Seoul, South Korea, and colleagues examined the association between AMD with and without visual disability (VD) an

Antibiotic exposure for 91 days or more was associated with an increased risk for rheumatoid arthritis.

Pediatric patients with anterior uveitis benefitted from seeing a rheumatologist and ophthalmologist together in one visit, as opposed to having separate visits with each specialist.

ACPA–negative individuals with clinically suspect arthralgia had reduced rates of RA development when treated with a 1-year course of methotrexate, compared with placebo.

Achieving weight loss within a year of initiating orlistat can reduce the risk for both incident gout and recurrent gout flares in patients with overweight or obesity.

Frailty emerged as an independent risk factor for severe infection and end-stage renal disease or death across different age groups in older adults with ANCA-associated vasculitis.

Systematically assessing risk factors, vaccination status, and screenings related to common diseases improved outcomes.

Rheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a study published online Aug. 6 in&nbsp;ACR Open Rheumatology.Yinan Huang, Ph.D., from the University of Mississippi in Oxford, and colleagues estimated the economic and humanistic burden of RA among

This is the fourth ustekinumab biosimilar approval in the United States, with the drug set to launch in 2025.

Patients with Sjögren disease had more damage to their oil-producing Meibomian glands than people with other varieties of dry eye.

Rheumatologists and lab specialists generally support consumers' ability to access tests without a doctor's order, but they remain aware of the possible harms that can come with practice.

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective signs of inflammation, and adults with active ankylosing spondylitis (AS).Bimzelx selectively inhibits two key cyt

Individuals who were men, seropositive, and smokers had a 7seven times higher risk for RA-UIP, the ILD subtype with a poor prognosis, than those without these risk factors.

Emapalumab-containing regimens showed positive outcomes in patients with rheumatologic disease–associated hemophagocytic lymphohistiocytosis, a rare and life-threatening disorder.

Rheumatology navigator programs vary in scope with different funding mechanisms. However, the prospect of getting paid by Medicare could open other reimbursement avenues for these patient advocates

The drug is the first and only dual IL-17A and IL-17F inhibitor approved to treat four chronic immune-mediated inflammatory diseases.

Hypnosis may be a feasible and cost-effective intervention for managing wound-related pain during the removal of skin ulcers in individuals with immune-mediated inflammatory diseases.

Two specialists are impressed by the preliminary findings of a randomized trial in newly diagnosed patients, but another is critical.

The prolonged use of muscle relaxants may offer pain relief in specific syndromes but can be associated with side effects such as drowsiness and dry mouth.

Adalimumab was superior to cyclosporine in preventing uveitis relapse in patients with severe Behçet disease already on corticosteroid therapy, according to randomized, open-label trial results.

In a clinical trial, nearly 60% of participants achieved remission and 41% fully tapered off oral corticosteroids.

Women were found to be underrepresented as authors in randomized controlled trials published in rheumatology from 2009 to 2023.

Christie Bartels discussed how rheumatology clinics can be utilized to tackle two common risk factors for heart disease without adding additional burden onto clinicians.

A data-driven analysis of a large cohort of patients with ANCA-associated vasculitis subclassified the condition into five distinct clusters, offering more accurate survival predictions.

Compared with placebo plus standard therapy, belimumab plus standard therapy led to higher rates of remission and low disease activity in patients with moderate to severe SLE.

The prolonged use of low-dose glucocorticoids is prevalent among older individuals with early rheumatoid arthritis in the United States, despite guidelines advising otherwise.

Hydroxychloroquine demonstrated protective effects against cardiovascular events in patients with systemic lupus erythematosus.

Gastrointestinal involvement should be considered in all pediatric patients with systemic lupus erythematosus, particularly if they have abdominal pain or elevated hepatic transaminases.

Greater consumption of specific alcoholic beverages, such as beer or cider, was associated with an increased risk for gout in both men and women, with a stronger effect observed in men.

The risk for lung cancer is high in patients with rheumatoid arthritis (RA) and pulmonary complications, according to a study published online Sept. 3 in&nbsp;Modern Rheumatology.Shunsuke Mori, M.D., Ph.D., from the Kumamoto Saishun Medical Center in Koshi, Japan, and colleagues assessed the incidence and predictive factors of lung canc

A computed tomography (CT)-based radiomics nomogram model can achieve favorable efficacy for predicting low-risk patients with rheumatoid arthritis (RA)-associated interstitial lung disease (ILD), according to a study published online July 31 in Frontiers in Immunology.Nie Han, from Guanghua Hospital Affiliated to the Shanghai Universit

Changes in colchicine pharmacokinetics due to drug-drug interactions did not result in meaningful changes in its safety and effectiveness, according to a secondary analysis of a clinical trial.

The more ultra-processed foods a person consumed, the higher their risk for the inflammatory autoimmune disease.

Both extreme heat and cold were tied to more severe episodes of Raynaud phenomenon in a study of participants with systemic sclerosis.

Two European studies reported on a potentially strong predictive biomarker for marginal lymphoma in Sjögren disease and the effectiveness of systemic therapy vs localized treatment or watch and wait.

Genetic predisposition to high ferritin and serum iron status is associated with a lower risk for developing rheumatoid arthritis (RA), according to a study published online Aug. 29 in Global Medical Genetics.Boyuan Wu, from the School of Global Public Health at New York University in New York City, used genetic data from a large gen

In small studies, teclistamab significantly improved autoimmune disease activity and demonstrated a good safety profile.

The presence of rheumatoid arthritis increased the risk for stroke in patients with atrial fibrillation, a retrospective study showed.

The risk of developing stage 3b chronic kidney disease was nearly doubled in patients with rheumatoid arthritis who had high disease activity.

For patients with rheumatoid arthritis, high-intensity interval training (HIIT) and strength exercise are beneficial for cardiovascular health, physical fitness, and overall health, according to a study published online Aug. 23 in the British Journal of Sports Medicine.Annelie Bilberg, Ph.D., from the University of Gothenburg Sahlgrens

Systemic sclerosis sine scleroderma may account for almost 10% of cases and shares clinical features with limited cutaneous systemic sclerosis.

OIG reports showed a spike in ustekinumab costs for patients in Medicare Part D. Experts said Inflation Reduction Act changes in Medicare drug coverage will soften the blow.

Two rheumatologists give insights about the great rewards of rheumatology volunteer work while also providing insights on its challenges across different settings.

Higher consumption of alcoholic beverages is associated with a higher risk for gout among both sexes, according to a study published online Aug. 28 in&nbsp;JAMA Network Open.Jie-Qiong Lyu, from Suzhou Medical College of Soochow University in China, and colleagues evaluated the consumption of total and specific alcoholic beverages in a

Exposure to high levels of particulate matter with diameter ≤ 10 μm was associated with an increased risk for giant cell arteritis but not ischemic complications, an observational study showed.

A support program for children recently diagnosed with juvenile idiopathic arthritis improved their physical, emotional, and psychosocial well-being, a recent study showed.

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

In patients with axial spondyloarthritis, bimekizumab — a dual interleukin-17A/F inhibitor — showed a lower incidence rate of uveitis, suggesting protective effects against acute anterior uveitis.

Cigna said on Monday it will remove AbbVie’s blockbuster rheumatoid arthritis drug Humira from some of its lists of preferred drugs for reimbursement in 2025, and recommend...

Adding etanercept in patients with early RA who responded insufficiently to initial methotrexate and bridging glucocorticoids did not result in better disease control than leflunomide at 104 weeks.

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

Janus kinase (JAK) inhibitor-associated acne may be overlooked outside of dermatology, experts said.

GLP-1 RAs were associated with a decreased risk for all-cause mortality and MACE in patients with immune-mediated inflammatory diseases and type 2 diabetes.

A self-guided smartphone-based behavioral therapy could be a viable treatment for fibromyalgia, a recent study showed.

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

Patients with hand osteoarthritis showed a high prevalence of tendon damage and inflammation of the synovial membrane surrounding the tendons.

Gastroesophageal reflux disease (GERD) increases the risk for rheumatoid arthritis (RA), according to a study published online Aug. 1 in&nbsp;Scientific Reports.Quan Yuan, from the First Hospital of Jilin University in Changchun, China, and colleagues used Mendelian randomization (MR) to assess the causal relationship between GERD an

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

A substantial proportion of patients with psoriasis, uveitis, or colitis and undiagnosed chronic back pain had axial spondyloarthritis, a study involving two multicenter cohorts showed.

There is a positive causal association for rheumatoid arthritis and adverse pregnancy outcomes (APOs), according to a study published online July 31 in&nbsp;BMC Pregnancy &amp; Childbirth.Tongmin Chang, from the Cheeloo College of Medicine at Shandong University in Jinan, China, and colleagues explored the potential causal relationships

Rheumatoid arthritis (RA) is associated with a significantly increased risk for lung cancer, according to a study published online July 28 in&nbsp;Arthritis &amp; Rheumatology.Rebecca T. Brooks, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues evaluated lung cancer risk in people with RA and RA-interstitial lung disease

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

Digital acceptance and commitment therapy (ACT) is safe and efficacious compared with daily digital symptom tracking for managing fibromyalgia, according to a study published online July 8 in&nbsp;The Lancet.R. Michael Gendreau, M.D., Ph.D., from Gendreau Consulting in Poway, California, and colleagues randomly assigned 275 adult partici

Patients with rheumatoid arthritis (RA) with moderate-to-high inflammation are more likely to experience cognitive impairment, according to a study published online July 29 in RMD Open.Natalia Mena-Vázquez, Ph.D., from the Biomedical Research Institute of Malaga and Platform in Nanomedicine in Spain, and colleagues performed a cross-

There is a causal association between genetically predicted rheumatoid arthritis (RA) and increased risk of bronchiectasis, according to a study published online June 19 in Frontiers in Medicine.Yuanyuan Li, from the Wuhan Fourth Hospital in China, and colleagues obtained RA genome-wide association study (GWAS) data and bronchiectasi

Approximately four in 10 patients with osteoarthritis (OA) or rheumatoid arthritis (RA) have anxiety, depression, or fibromyalgia, according to a study published online July 16 in&nbsp;ACR Open Rheumatology.Juan Schmukler, M.D., from the Rush University Medical Center in Chicago, and colleagues analyzed the prevalence of anxiety, dep

Greater adherence to a Mediterranean diet is associated with lower odds of depression in individuals with rheumatoid arthritis, according to a study published online July 5 in the&nbsp;Journal of Health, Population and Nutrition.Liya Ma, from Honghui Hospital at Xi’an Jiaotong University in China, and colleagues explored the associatio

Socioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 in RMD Open.Maryam Adas, from the King's College London Faculty of Life Sciences &amp; Medicine, and colleagues examined which biological and nonbiological factors are associated w

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.The disease appears to be caused by malfunctions in an immune system pathway that regulates cells’ response to environmental pollutants, bacteria and toxins.Insufficient activation of this pathwa

Air pollutant exposure is associated with an increased likelihood of developing incident systemic lupus erythematosus (SLE), according to a study published online July 10 in Arthritis &amp; Rheumatology.Meiqi Xing, from the Huazhong University of Science and Technology in Wuhan, China, and colleagues examined the associations between

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

Psoriasis is associated with fatigue, especially among those with psoriatic arthritis (PsA), according to a study published in the July issue of the Journal of the American Academy of Dermatology.Lea Nymand, from Bispebjerg Hospital and the University of Copenhagen in Denmark, and colleagues explored the characteristics of fatigue and it

Rheumatoid arthritis (RA) patients with mono- or oligo-arthritis and high Patient Global Assessment (PGA) at diagnosis remain the most fatigued, according to a study published in the June issue of Rheumatology.Anna M.P. Boeren, from the Leiden University Medical Center in the Netherlands, and colleagues studied Disease Activity&nbsp;Sco

For patients with rheumatoid arthritis (RA), a detectable level of high-sensitivity cardiac troponin T (hs-cTnT) is associated with increased risk of major adverse cardiovascular events (MACE) and all-cause mortality, according to a research letter published online June 15 in the Journal of Rheumatology.Brittany N. Weber, M.D., Ph.D.,

The Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional Questionnaire (BRAF-MDQ) and Brief Fatigue Inventory (BFI-C) scores show consistency in assessing fatigue with rheumatoid arthritis (RA), according to a study published online June 14 in&nbsp;Immunity, Inflammation and Disease.Jun Zhou, from the Affiliated Suqian First People

Patients who have smoked with rheumatoid arthritis (RA) and an obstructive pattern may be a unique phenotype, according to a study published online June 17 in&nbsp;RMD Open.Keigo Hayashi, M.P.H., from Brigham and Women's Hospital in Boston, and colleagues compared longitudinal changes in spirometric measures over five to seven years be

The U.S. Food and Drug Administration has expanded indications for Rinvoq (upadacitinib) to now include pediatric patients (ages 2 years and older) with polyarticular juvenile idiopathic arthritis (pJIA) and psoriatic arthritis (PsA).Rinvoq is indicated for pediatric patients with an inadequate response or intolerance to one or more tumor necros

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

Metformin use not only prevented the progression to diabetes but also lowered the risk for gout in individuals with prediabetes.

More than 40% of patients with IBD screened positive for joint pain in a multicenter study, yet few patients had seen a rheumatologist in the past year.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Findings from a qualitative study suggested a greater need for rheumatology clinicians to initiate discussions with patients about neuropsychiatric symptoms.

There was no difference in the risk for hypertension between patients with axial spondylarthritis who were high and low NSAID users, according to new data.

Patients with fibromyalgia and irritable bowel syndrome (IBS) have increased rates of severe multiple drug intolerance syndrome (MDIS), according to a study published in the May issue of the Journal of Allergy and Clinical Immunology: In Practice.Alicia A. Alvarez, M.D., from Sarasota Memorial Hospital in Florida, and colleagues conduc

The U.S. Food and Drug Administration has approved a 200-mg subcutaneous route of administration of Benlysta (belimumab) for patients 5 years of age and older with active systemic lupus erythematosus (SLE) who are receiving standard therapy.The B-lymphocyte stimulator-specific inhibiting monoclonal antibody was previously approved for children

Including over 4670 patients, this is "the largest cohort study to date looking specifically at the association of [HCQ] retinopathy with risk factors," one expert said.

This enables at-home administration of the medication, which was previously available only via intravenous infusion.

For patients with systemic lupus erythematosus (SLE), neuropsychiatric (NP) symptoms can first present at any stage in the disease course, according to a study published online May 20 in eClinicalMedicine.Melanie Sloan, Dr.P.H., from the University of Cambridge in the United Kingdom, and colleagues obtained patient reports of the timing

Disease-modifying antirheumatic drugs can reduce some cardiovascular risk in patients with rheumatoid arthritis, but questions remain if that's enough when statin use lags.

Growing evidence suggests that a guideline-directed, treat-to-target strategy in patients with gout not only controls the disease but also reduces cardiovascular risks.

Researchers are looking to see if GLP-1 receptor agonists, DPP4 inhibitors, and SGLT2 inhibitors have beneficial effects in osteoarthritis.

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Factors associated with an increased risk for hydroxychloroquine retinopathy have been identified and include female sex, older age, and chronic kidney disease stage 3 or greater, according to a study published online May 9 in JAMA Network Open.April M. Jorge, M.D., from Massachusetts General Hospital in Boston, and colleagues identified

Psoriatic arthritis (PsA) and atopic dermatitis (AD) can coexist, and the presence of both conditions may mean special attention should be given to selecting optimal treatment, according to a study published online April 17 in the Journal of Personalized Medicine.Georgiana Strugariu, from "Grigore T. Popa" University of Medicine and Phar

In a prospective study, all patients diagnosed with giant cell arteritis using ultrasound maintained their diagnosis for up to 2 years of follow-up.

The trial proved that nipocalimab reduced IgG antibodies, including anti-citrullinated protein autoantibodies, but the primary endpoint was missed.

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

A recent study revealed that alterations in the serum metabolome indicated the presence of concurrent cancer in patients with rheumatic diseases or paraneoplastic syndromes mimicking rheumatic symptoms.

NSAIDs, the primary pain management therapy for AS, increased the risk for vascular events and congestive heart failure when administered in high doses to patients with AS.

bDMARD therapy preserved renal function in 75% of patients with AA amyloidosis, but the remaining 25% progressed to ESRD despite receiving bDMARD therapy.

A history of pregnancy complications can put women with autoimmune disease at a higher risk for CVD. Prophylaxis during pregnancy may avoid those complications in the first place.

Data do not back the use of diacerin, resveratrol, or botulinum toxin for knee OA, according to the results of well-performed, multicenter, randomized controlled clinical trials.

People with low lower-limb muscle mass should consider non–weight-bearing physical activities, along with strengthening exercises, to potentially reduce their risk of developing knee OA.

Data on several novel injectable drugs were presented at the World Congress on Osteoarthritis, as well as updated data on the gene therapy XT-150.

For patients with high clinical suspicion of giant cell arteritis (GCA), color Doppler ultrasound of the temporal artery as a first-line diagnostic tool can avoid the need for other diagnostic tests, according to a study published online May 7 in the Annals of Internal Medicine.Guillaume Denis, M.D., from the Centre Hospitalier Rochefort

Recent regulatory warnings could mean that four in five patients with RA may not be prescribed JAK inhibitors unless there is no other alternative.

A machine learning algorithm can identify patients with common variable immunodeficiency disease (CVID) from their electronic health records, according to a study published in the May 1 issue of Science Translational Medicine.Due to the low prevalence and extensive heterogeneity in CVID phenotypes, resulting in delayed diagnoses and tre

Unlike the low-concentration formulation of adalimumab-adbm, launched July 1, 2023, this high-concentration version has not yet been granted an interchangeability designation.

Patients with seropositive RA on stable DMARD therapy showed a CVD risk comparable with that of the general population, unlike those whose treatment regimen was not stable.

An updated guideline on the management of Sjögren disease has been produced by the British Society for Rheumatology, providing practical advice for healthcare professionals and the people they treat.

Irrespective of age, duration of disease, and other factors, people with rheumatoid arthritis have a consistently higher risk for venous thromboembolism than the general population.

Fracture risk is nearly doubled in individuals with acute calcium pyrophosphate (CPP) crystal arthritis, according to a study recently published in Arthritis &amp; Rheumatology.Sara K. Tedeschi, M.D., M.P.H., from Brigham and Women’s Hospital in Boston, and colleagues compared fracture risks (humerus, wrist, hip, or pelvis) in 1,148 pa

Almost all people who received in-hospital treatment for a gout flare were using urate-lowering therapy within 6 months of discharge after a multifaceted intervention with nurse-led follow-up.

Inflammatory arthritis codes increased from 14 to 425 from ICD-9 to ICD-10, yet only nine codes were commonly used in practice from 2015 to 2021.

The British Society for Rheumatology and the British Association of Dermatologists developed guidelines for the management of people living with Behçet's disease.

Results of the STEP 9 study in people with knee OA and obesity show that semaglutide not only induced significant weight loss but also improved knee pain and physical function.

Patients with GPA were two to three times as likely to experience disease relapse if they scored high on a patient-reported sinonasal symptom test.

Advanced systems for measuring patient-reported outcomes can help improve care of patients with rheumatoid arthritis and inform clinical research.

Plugging massive amounts of data from EHRs into AI systems may turn masses of silicon chips into crystal balls for foretelling treatment efficacy.

Patients with rheumatic diseases who live in underserved areas may benefit from virtual visits conducted jointly by rheumatologists and PCPs trained in recognizing and managing these conditions.

The biosimilar is expected to be marketed in the United States on or after February 21, 2025.

Investigators have found evidence suggesting that bad bugs in the belly may contribute to inflammation in the joints, and that modulating gut microbes could improve rheumatoid arthritis treatment.

Guselkumab improved joint swelling, spinal pain, skin symptoms, and overall disease activity in a substantial number of patients with psoriatic arthritis through 2 years.

In two trials, most patients with RA in remission who tapered csDMARD or TNF inhibitor drugs to withdrawal experienced flares within 3 years.

PsA is more prevalent in Europe and North America than in Asia and South America, according to a meta-analysis that assessed the worldwide PsA prevalence.

Maintaining a healthy body composition is important to improve physical functioning and mobility in patients with axial spondyloarthritis receiving biologics, a new study indicated.

A prospective study found that 96% of patients with RA-ILD had at least one serious infection, which proved fatal in 65% of cases.

Patients with juvenile idiopathic arthritis achieved long-term disease control with subcutaneous tocilizumab treatment, without any new safety concerns, in an LTE study of two trials.

Longer tocilizumab administration intervals and lower prednisolone doses seemed pivotal for successful tocilizumab withdrawal while maintaining remission in patients with AOSD.

Although largely similar, some important histopathologic differences were seen in the biopsies of the labial and parotid salivary glands in individuals with suspected SjS.

The trial is expected to begin this summer and will enroll 12 individuals under age 18 years.

Progressive resistance training or neuromuscular exercise for 12 weeks helped to improve hip function, pain, and quality of life to a similar degree in people with osteoarthritis.

This is the first stand-alone arthritis research program under the Department of Defenses' Congressionally Directed Medical Research Programs.