All articles tagged: Pathology

A nationwide, couple-based reproductive carrier screening program has demonstrated feasibility in informing reproductive decision-making, according to a study published in the Nov. 21 issue of the New England Journal of Medicine.Edwin P. Kirk, M.B., B.S., Ph.D., from the Sydney Children's Hospital, and colleagues examined the feasibi

Teledermoscopy has high accuracy for detecting skin cancers, according to a research letter published online Nov. 9 in the Journal of the American Academy of Dermatology.Jenne P. Ingrassia, from New York Medical College in Valhalla, and colleagues conducted a prospective diagnostic accuracy study to compare the accuracy of telemedici

A child in California has tested positive for bird flu, despite having no known contact with infected animals, state officials reported Tuesday."California has identified a possible bird flu case in a child in Alameda County who was tested for mild upper respiratory symptoms. The child, who ha

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

The use of personal care products (PCPs) such as hair dyes may be a modifiable source of per- and polyfluoroalkyl substance (PFAS) exposure in pregnant and lactating populations, according to a study published online in the November issue of Environment International.Amber M. Hall, Ph.D., from Brown University in Providence, Rhode Isla

As Africa continues to battle an outbreak of the newer "clade Ib" strain of mpox, California officials have confirmed the first known U.S. case of this strain of the virus.The subtype of clade I mpox virus has already caused widespread misery in Congo and other African nations."This case was confirmed in an individual who recently travele

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

Neoantigen DNA vaccines are safe and capable of inducing neoantigen-specific immune responses in patients with triple-negative breast cancer, according to a study published online Nov. 14 in Genome Medicine.Xiuli Zhang, M.D., from the Washington University School of Medicine in St. Louis, and colleagues developed a neoantigen DNA vacc

Amid an ongoing outbreak of bird flu in American dairy herds and poultry flocks, Canadian officials have announced that a teen in British Columbia has been hospitalized in critical condition with what is believed to be bird flu.It’s not clear how the teenager picked up the H5N1 virus because the patient is not known to have any contact with i

Health care facilities should consider initiating or expanding admission screening for Candida auris based on community prevalence rates, according to a study published online Oct. 31 in the American Journal of Infection Control.Aaron Cheng, M.P.H., from Mount Sinai Beth Israel in New York City, and colleagues exa

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

Some pesticides are associated with increased prostate cancer incidence and mortality, according to a study published online Nov. 4 in Cancer.Simon John Christoph Soerensen, M.D., from the Stanford University School of Medicine in California, and colleagues examined the potential role of agricultural pesticide exposure in prostate cancer

Lack of health insurance coverage accounts for a considerable proportion of racial and ethnic disparities in advanced-stage diagnoses of cancer, according to a study published online Oct. 30 in the Journal of the National Cancer Institute.Parichoy Pal Choudhury, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined

Amid an ongoing outbreak of bird flu in poultry and dairy cows in the United States, a case of H5N1 has now been confirmed for the first time in a pig."The U.S. Department of Agriculture [USDA] and Oregon state veterinary officials are investigating positive cases of H5N1 in a backyard farming operation in Oregon that has a mix of poultry

There seems to be a significant association between hypothyroidism, Hashimoto thyroiditis, subacute thyroiditis, and alopecia areata (AA), according to a study published in the October issue of Skin Research & Technology.Yue Zhao, from Heping Hospital Affiliated to Changzhi Medical College in China, and colleagues examined the po

Cell-free DNA blood tests (cf-bDNA) may be more costly and less effective for colorectal cancer (CRC) screening than other screening modalities, according to a study published online Oct. 29 in the Annals of Internal Medicine.Uri Ladabaum, M.D., from the Stanford University School of Medicine in California, and colleagues estimated t

Absolute concentrations of fentanyl, methamphetamine, and cocaine in urine specimens increased from 2013 to 2023, according to a study published online Oct. 24 in JAMA Network Open.Andrew S. Huhn, Ph.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues analyzed urine drug testing (UDT) results to q

Genome sequencing of newborns is both feasible and acceptable for parents of a diverse newborn population, according to a study published online Oct. 24 in the Journal of the American Medical Association.Alban Ziegler, M.D., from the Columbia University Irving Medical Center in New York City, and colleagues reported interim result

A second person in Missouri who wasn't exposed to either poultry or dairy cows has been infected with bird flu, U.S. health officials reported Thursday.This person shared a home with a patient who was first hospitalized with bird flu in August, but antibody tests have since shown that symptomatic health care workers who cared for the patient wer

The fibrinogen-to-albumin ratio (FAR) is an independent risk factor for development of any preeclampsia (PE) and PE with severe features (sPE), according to a study presented at the annual meeting of the American Society of Anesthesiologists, held from Oct. 18 to 22 in Philadelphia.Lucy Shang, from the Icahn School of Medicine at Mount Sinai i

For patients with ulcerative colitis, the HLA-DRB1*01:03 allele is associated with severe ulcerative colitis, according to a research letter published online Oct. 15 in the Journal of the American Medical Association to coincide with the United European Gastroenterology Week, held from Oct. 12 to 15 in Vienna.Marie Vibeke Vestergaard, f

The International Ovarian Tumour Analysis consortium (IOTA) Assessment of Different Neoplasias in the Adnexa (ADNEX) at 10 percent is more sensitive, but less specific, for diagnosing ovarian cancer compared with Risk of Malignancy 1 (RMI1) at 250, according to a study published in the October issue of The Lancet Oncology.Sudha Sunda

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

For patients with glioblastoma imaged daily with magnetic resonance imaging (MRI)-linear accelerator (linac) throughout the chemoradiation therapy course, anatomic changes can be detected, according to a study published online Sept. 30 in the International Journal of Radiology Oncology - Biology - Physics.Kaylie Cullison, Ph.D., from th

The presence of persistent antigen is associated with having postacute sequelae of COVID-19 (PASC) symptoms, according to a study published online Oct. 8 in Clinical Microbiology and Infection.Zoe Swank, Ph.D., from Brigham and Women's Hospital in Boston, and colleagues assessed the proportion of individuals with detectable antig

As health officials work furiously to stem the spread of Marburg virus in Rwanda, U.S. health officials announced Monday that all passengers flying from that country to the United States will soon be screened for the often deadly disease."Starting the week of October 14, CDC [U.S. Centers for Disease Control and Prevention] will begin public hea

For umbilical cord blood transplant (UCBT), overall survival has improved over time, according to a study published in the October issue of Transplantation and Cellular Therapy.Karen Ballen, M.D., from the University of Virginia Health System in Charlottesville, and colleagues compared outcomes of UCBT by social determinants of health in

A pair of American scientists have won the 2024 Nobel Prize in medicine for their discovery of microRNA, tiny genetic molecules that play a crucial role in how genes shape the body.The research of Victor Ambros and Gary Ruvkun “revealed a new dimen

A pair of American scientists have won the 2024 Nobel Prize in medicine for their discovery of microRNA, tiny genetic molecules that play a crucial role in how genes shape the body.The research of Victor Ambros and Gary Ruvkun “revealed a new dimen

Integrated cell-free DNA (cfDNA) fragmentome and protein analyses detect ovarian cancers with high performance, according to a study published online Sept. 30 in Cancer Discovery.Jamie E. Medina, Ph.D., from the Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins University School of Medicine in Baltimore, and colleagues used

As an outbreak of bird flu among dairy cows continues to spread in the United States, two more cases have been reported in dairy workers, this time in California.These are the first human cases of bird flu reported in that state and the 15th and 16th human cases detected in the country this year, the U.S. Centers for Disease Control and Preventio

The dissociation between pathological caloric testing and a normal video head impulse test can differentiate between Meniere disease (MD) and vestibular migraine (VM), according to a study published online Aug. 14 in Frontiers in Neurology.Vergil Mavrodiev, from LMU University Hospital in Munich, and colleagues examined the sensitivity

Circulating antibodies against cancer-testis antigens (CTAgs) are found in stage I and stage II melanoma plasma samples, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Cristina Vico-Alonso, M.D., from Monash University Public Health and Preventi

Certain oral bacteria are a risk factor for development of head and neck squamous cell cancer (HNSCC), according to a study published online Sept. 26 in JAMA Oncology.Soyoung Kwak, Ph.D., from the New York University Grossman School of Medicine in New York City, and colleagues tested whether oral bacterial and fungal microbiomes

Upward trends in breast cancer incidence among women have continued, according to a study published online Oct. 1 in CA: A Cancer Journal for Clinicians.Angela N. Giaquinto, M.S.P.H., from the American Cancer Society in Atlanta, and colleagues presented the biennial update of statistics on breast cancer among women using incidence and m

A rare, highly contagious Ebola-like virus has claimed eight lives in Rwanda, and U.S. health officials are closely monitoring the outbreak.Marburg virus causes a rare hemorrhagic fever that has no authorized vaccine or treatment.No cases related to the Rwanda outbreak have been reported in the United States, and the current risk to Ameri

Few patients with abnormal protein dipstick results have follow-up albuminuria quantification, according to a research letter published online Oct. 1 in the Annals of Internal Medicine.Noting that guidelines recommend follow-up albumin-creatinine ratio (ACR) testing if the protein dipstick test result is abnormal, Yunwen Xu, Ph.D., fro

For patients with suspicion for prostate cancer, transperineal biopsy has similar cancer detection rates as transrectal biopsy but a significantly lower risk for infection, according to a research letter published online Sept. 19 in JAMA Oncology.Jim C. Hu, M.D., M.P.H., from the New York Presbyterian Weill Cornell Medicine Hospital in

Measles cases in England are consistent with the waning of vaccine-induced immunity, according to a study published online Sept. 26 in The Lancet Public Health.Alexis Robert, Ph.D., from the London School of Hygiene & Tropical Medicine, and colleagues examined whether measles dynamics observed in England between 2010 and 2019 were

In what could be the first cases of bird flu spreading between humans in the United States, a group of potential H5N1 infections in Missouri has now grown to eight.Antibody tests to confirm any H5N1 infection are still pending.After a patient with bird flu was hospitalized last month, state and federal health officials first determined t

Casual blood glucose (CBG) testing at 24 to 28 gestational weeks misses about 70 percent of women with gestational diabetes mellitus (GDM), according to a study published online Sept. 18 in the Journal of Diabetes Investigation.Masako Tomimoto, M.D., from the Kobe University Graduate School of Medicine in Japan, and colleagues enrolled

The free COVID-19 tests promised by the U.S. government are now available."U.S. households will be eligible to order four free COVID-19 tests at COVIDTests.gov," according to the U.S. Department of Health and Human Services. "The COVID-19 tests will detect current COVID-19 variants and can be used through the end of the year."More than

For patients with hemophilia B, fidanacogene elaparvovec, an adeno-associated virus (AAV) gene-therapy vector for hemophilia B containing a high-activity human factor IX variant, is superior to prophylaxis, according to a study published in the Sept. 26 issue of the New England Journal of Medicine.Adam Cuker, M.D., from the Universit

The U.S. government is offering another round of free COVID-19 tests, which will be available by the end of September."U.S. households will be eligible to order four free COVID-19 tests at COVIDTests.gov," according to the U.S. Department of Health and Human Services. "The COVID-19 tests will detect current COVID-19 variants and can be used

In a clinical review conducted by an international committee of multiple sclerosis (MS) experts in pediatric and adult MS and published online Sept. 16 in JAMA Neurology, consensus guidance is provided for diagnosing pediatric and late-onset MS.Le H. Hua, M.D., from the Lou Ruvo Center for Brain Health at the Cleveland Clinic in Las V

Metal exposure from environmental pollution is associated with the progression of atherosclerosis, according to a study published online Sept. 18 in the Journal of the American College of Cardiology.Katlyn E. McGraw, Ph.D., from the Columbia University Mailman School of Public Health in New York City, and colleagues examined whet

Exposure to toxic metals and alterations in essential metal homeostasis are associated with faster increases in glycemia over time in a high-risk Mexican American population, according to a study published online Sept. 15 in Diabetes Care.Margaret C. Weiss, from the University of Illinois at Chicago, and colleagues examined continuous

Another health care worker who was exposed to a Missouri patient who tested positive for bird flu developed respiratory symptoms but wasn't tested for the flu, U.S. health officials reported Friday.The news is rekindling worries of person-to-person transmission of the H5N1 bird flu strain.The week before, the U.S. Centers for Disease Con

High levels of well-being may protect against the risks for cardiovascular diseases (CVDs), according to a study published online Sept. 18 in the Journal of the American Heart Association.Jinghui Zhong, from the University of Science and Technology of China in Hefei, and colleagues used data from 121,317 participants in the U.K. B

The findings from influenza A virus and H5 subtype monitoring of wastewater have been published in the Sep. 19 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Souci Louis, V.M.D., from the CDC in Atlanta, and colleagues present the results of monitoring influenza A virus levels and d

For women with at least four embryos available during in vitro fertilization (IVF) treatment, blastocyst embryo transfers result in a similar cumulative live birth rate to cleavage stage embryo transfers after oocyte retrieval, according to a study published online Sept. 16 in The BMJ.Simone Cornelisse, M.D., from Radboud University

Melanoma rates differ for men and women, including in terms of ages of occurrence and locations of melanoma, according to a study published online June 17 in the Journal of Investigative Dermatology.Catherine M. Olsen, Ph.D., from the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and colleagues analyzed long-term m

For the second time this year, the Senate plans to vote Tuesday on a law that would create a nationwide right to IVF.The bill was already blocked by Republicans earlier this year, but Democrats are hoping to use this second vote to pressure Republican congressional candidates on the hot button issue, the Associated Press reported.

In a disclosure that can't eliminate the possibility that bird flu may have spread from one human to another for the first time, U.S. health officials have reported that a person who lived with a Missouri resident infected with H5N1 became sick the same day.That close contact "was also ill at the same time, was not tested, and has since recover

More than 70 percent of patients with stage I pancreatic ductal adenocarcinoma (PDAC) and close to 30 percent with stage II PDAC are upstaged on histopathology, according to a research letter published online Sept. 5 in the Journal of the American Medical Association.Gerardo Perrotta, M.D., from Cedars-Sinai Medical Center in Los Angele

Air pollution is associated with a higher risk for an infertility diagnosis in men, while road traffic noise pollution is associated with a higher risk for an infertility diagnosis in women aged 35 years and older, according to a study published online Sept. 4 in The BMJ.Mette Sørensen, Ph.D., from the Danish Cancer Institute in Co

The risk for lung cancer is high in patients with rheumatoid arthritis (RA) and pulmonary complications, according to a study published online Sept. 3 in Modern Rheumatology.Shunsuke Mori, M.D., Ph.D., from the Kumamoto Saishun Medical Center in Koshi, Japan, and colleagues assessed the incidence and predictive factors of lung canc

As mpox continues to spread in Africa, Congolese authorities said Thursday that the first batch of vaccines have arrived in that country's capital.The shipment comes three weeks after the World Health Organization declared mpox outbreaks in 12 African countries a&nbsp;<a href="https://www.who.int/news/item/14-08-2024-who-director-general-de

World Trade Center (WTC) exposure is associated with increased DNA methylation, which may contribute to breast cancer, according to a study published in the June issue of Environmental Epidemiology.Stephanie Tuminello, Ph.D., M.P.H., from the NYU Grossman School of Medicine in New York City, and colleagues examined the DNA methylation

Genetic predisposition to high ferritin and serum iron status is associated with a lower risk for developing rheumatoid arthritis (RA), according to a study published online Aug. 29 in Global Medical Genetics.Boyuan Wu, from the School of Global Public Health at New York University in New York City, used genetic data from a large gen

The association of prenatal ω-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) with the risk for childhood atopic dermatitis (AD) varies based on the maternal cyclooxygenase-1 (COX1) genotype, according to a study published online Aug. 28 in JAMA Dermatology.Liang Chen, from Herlev and Gentofte Hospital in Copenhagen, Denmark, an

In patients with newly diagnosed type 2 diabetes, baseline interleukin-6 (IL-6) levels may enhance prediction of new-onset obesity-related cancers, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.Mathilde Dahlin Bennetsen, from th

A number of U.S. travelers returning from Cuba have been diagnosed with Oropouche virus, according to research published in the Aug. 27 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Noting that there have been reports of two deaths in patients with Oropouche virus infec

A single combined measure of high-sensitivity C-reactive protein (CRP), low-density lipoprotein (LDL) cholesterol, and lipoprotein(a) levels predict the 30-year risk for incident cardiovascular events in healthy U.S. women, according to a study published online Aug. 31 in the&nbsp;New England Journal of Medicine&nbsp;to coincide with the Euro

Fecal immunochemical tests (FITs) have variable sensitivity and specificity for detecting advanced colorectal neoplasia (ACN), according to a study published online Sept. 3 in the Annals of Internal Medicine.Barcey T. Levy, M.D., Ph.D., from the University of Iowa Carver College of Medicine in Iowa City, and colleagues compared the per

Multiple sclerosis (MS) is associated with a lower risk for Alzheimer disease, according to a study published in the September issue of the Annals of Neurology.Noting that development of typical Alzheimer disease dementia syndrome is uncommon in people with MS, Matthew R. Brier, M.D., Ph.D., from Washington University in St. Louis, and

In middle-aged individuals with Down syndrome (DS), lecanemab-labeled amyloid plaques are seen in postmortem brain tissue analysis, in addition to extensive binding to brain blood vessels, according to a study published online Aug. 19 in JAMA Neurology.Lei Liu, M.D., Ph.D., from Brigham and Women's Hospital in Boston, and colleagues ex

Comprehensive human papillomavirus (HPV) screening, including genotyping, is important in urology and fertility clinics, according to a study published online Aug. 23 in Frontiers in Cellular and Infection Microbiology.Carolina Olivera, Ph.D., from the FOCIS Center of Excellence Centro de Inmunología Clínica de Córdoba in Argentina, and

Low-grade systemic inflammation across childhood and adolescence is associated with the subsequent onset of mental health disorders, according to a study published online Aug. 21 in JAMA Psychiatry.Edward R. Palmer, M.B.B.S., from the University of Birmingham in the United Kingdom, and colleagues examined trajectories of inflammation, a

Elevated salivary levels of CD44 and total protein (TP) can identify head and neck cancer patients with an increased risk for cancer recurrence, according to a study published online Aug. 15 in JAMA Otolaryngology-Head and Neck Surgery.Elizabeth J. Franzmann, M.D., from the University of Miami Health System and Jackson Memorial Hospit

Childhood maltreatment is associated with later cognitive difficulties, according to a study published in the September issue of&nbsp;The Lancet Psychiatry.Andrea Danese, M.D., Ph.D., from King's College London, and Cathy Spatz Widom, Ph.D., from the John Jay College City University of New York in New York City, evaluated association

From 2020 to 2021, life expectancy at birth declined for 39 U.S. states and increased for 11 states, according to the Aug. 21 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Elizabeth Arias, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues p

Artificial intelligence (AI) is able to distinguish Marfan from non-Marfan facial images using ordinary online photographs with an extremely high degree of accuracy, according to a study published in the July 15 issue of Heliyon.Danny Saksenberg, from the Yale University School of Medicine in New Haven, Connecticut, and colleagues ex

Increased activity of the insect-borne Oropouche virus has prompted warnings from the U.S. Centers for Disease Control and Prevention for travelers to South America and the Caribbean.Oropouche virus has caused two deaths and five cases of fetal death or birth defects a

An artificial intelligence (AI) tool can exclude pathology, with an equal or lower rate of critical misses on radiographs than radiologists, according to a study published online Aug. 20 in Radiology.Louis Lind Plesner, M.D., from Herlev and Gentofte Hospital in Denmark, and colleagues estimated the proportion of unremarkable chest rad

Low levels of magnesium with or without high homocysteine (Hcy), are associated with increased DNA damage, according to a study recently published in the European Journal of Nutrition.Varinderpal S. Dhillon, Ph.D., from the University of South Australia in Adelaide, and colleagues examined whether magnesium deficiency alone or in conjun

As syphilis cases surge throughout the United States, the U.S. Food and Drug Administration on Friday approved the first diagnostic at-home test to spot the bacterial disease."This is the first at-home, over-the-counter test to detect Treponema pallidum [syphilis] antibodies in human blood," the FDA said in a <a href="https://www.fda.go

Symptom-triggered testing can identify women with high-grade serous ovarian cancer with low disease burden, according to a study published online Aug. 13 in the International Journal of Gynecological Cancer.Fong Lien Audrey Kwong, from The Pan-Birmingham Gynaecological Cancer Centre at the Sandwell and West Birmingham NHS Trust in the U

For children with recurrent respiratory tract infections (rRTIs), serum antibody levels are not associated with respiratory disease severity, but salivary polyreactive immunoglobulin (Ig)A and Haemophilus influenzae are associated with severity, according to a study published online Aug. 8 in the European Respiratory Journal.Mi

As an outbreak of a new strain of mpox continues in Africa, Sweden announced Thursday that it has confirmed the first case in that country.Known as the clade I strain, this latest iteration of mpox appears to be spread more easily and cause more severe disease, experts say."A person who sought care at Region Stockholm has been diagnosed w

The World Health Organization on Wednesday made the rare move of declaring an ongoing African outbreak of mpox a global health emergency.A new clade (strain) of the virus, plus its troubling spread throughout the Democratic Republic of Congo (DRC) and nearby countries in central Africa, drove the declaration, said WHO director general <a href=

In a health alert issued by the U.S. Centers for Disease Control and Prevention, the agency said it has received reports of higher test positivity rates for parvovirus B19 in recent months: The proportion of people with antibodies indicating recent infection, which fell below 3 percent from 2022 to 2024, spiked to 10 percent in June.But child

Gastroesophageal reflux disease (GERD) increases the risk for rheumatoid arthritis (RA), according to a study published online Aug. 1 in&nbsp;Scientific Reports.Quan Yuan, from the First Hospital of Jilin University in Changchun, China, and colleagues used Mendelian randomization (MR) to assess the causal relationship between GERD an

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

Routine clinical laboratory values do not serve as biomarkers for postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC), according to a study published online Aug. 13 in the Annals of Internal Medicine.Kristine M. Erlandson, M.D., from the University of Colorado Anschutz Medical Campus in A

Elevated metal levels in plasma and urine are associated with amyotrophic lateral sclerosis (ALS) risk and survival, according to a study published online Aug. 6 in the Journal of Neurology, Neurosurgery &amp; Psychiatry.Dae-Gyu Jang, Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined associations of metal measu

There are racial differences in the frequency of skin biopsy for psoriasis, indicating diagnostic uncertainty, according to a research letter published online Aug. 7 in JAMA Dermatology.Fahad Ahmed, from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and colleagues conducted a cross-sectional study inv

The assessment of cancer risk based on symptoms, age, and sex can be enhanced by considering information from common blood test results among patients presenting with nonspecific abdominal symptoms, according to a study published online July 30 in PLOS Medicine.Meena Rafiq, M.D., Ph.D., from University College London, and colleagues quan

In 2023, there was a provisional total of 3,090,582 deaths in the United States, according to research published in the Aug. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Farid B. Ahmad, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues

U.S. doctors should be on the lookout for a more severe strain of mpox that is spreading widely in parts of Africa, federal health officials warned Wednesday.The&nbsp;alert,&nbsp;issued by the U.S. Centers for Disease Control and Prevention, came just hours after the World Health Org

In 2021, the estimated total health care costs for initial cancer screening were $43 billion in the United States, according to a study published online Aug. 6 in the Annals of Internal Medicine.Michael T. Halpern, M.D., Ph.D., from the National Cancer Institute in Bethesda, Maryland, and colleagues estimated the annual cost of initial c

Stringent state-level COVID-19 restrictions were associated with substantial decreases in pandemic mortality, according to a study published online July 26 in JAMA Health Forum.Christopher J. Ruhm, Ph.D., from the Frank Batten School of Leadership and Public Policy at the University of Virginia in Charlottesville, examined how state rest

Mpox cases have soared by 160% in Africa this year, as a lack of both vaccines and treatments hamper efforts to slow the spread of the virus.In a report released by the Africa Centers for Disease Control and Prevention on Wednesday, officials said that mpox has now been detec

For patients with Gleason Grade Group (GGG) 1 prostate cancer (PC), those with percentage positive biopsies (PPB) &gt;50 percent or prostate-specific antigen (PSA) &gt;20 ng/mL have a significantly increased risk for adverse outcomes, according to a study published online July 2 in European Urology Oncology.Derya Tilki, M.D., from Univ

Plasma biomarkers of Alzheimer disease (AD) neuropathy increase with age and are associated with known dementia risk factors, according to a study published online July 28 in the Journal of the American Medical Association to coincide with the Alzheimer's Association International Conference, held from July 28 to Aug. 1 in Philadelphia.<p

The amyloid probability score 2 (APS2) has high diagnostic accuracy for identifying Alzheimer disease (AD) among individuals with cognitive symptoms in primary and secondary care, according to a study published online July 28 in the Journal of the American Medical Association to coincide with the Alzheimer's Association International Confer

Measures of familial loss experienced from childhood to adulthood are associated with biological aging, according to a study published online July 29 in JAMA Network Open.Allison E. Aiello, Ph.D., from the Mailman School of Public Health at Columbia University in New York City, and colleagues examined the associations of losing a paren

Pesticide usage is associated with an increased incidence of cancer, according to a study published online July 25 in Frontiers in Cancer Control and Society.Jacob Gerken, D.O., from the Rocky Vista University College of Osteopathic Medicine in Englewood, Colorado, and colleagues examined the relationship between pesticides and cancer

The U.S. Food and Drug Administration on Monday approved a new blood test that can spot colon cancer.In late May, an FDA advisory panel had voted 7-2 that the benefits outweigh the risks when using the Guardant Health's Shield test for&n

Hematopoietic cell transplantation (HCT) donors' socioeconomic status (SES) affects recipients' health outcomes, according to a study published online July 15 in PNAS.Lucie M. Turcotte, M.D., M.P.H., from the University of Minnesota Medical School in Minneapolis, and colleagues examined the cellular transplantability of SES-associated

For girls and young women with sickle cell disease (SCD), exposure to hydroxyurea does not reduce ovarian reserve, according to a study published online July 18 in Blood Advances.Tamara Diesch-Furlanetto, Ph.D., from the University of Basel Children's Hospital in Switzerland, and colleagues counted follicles and categorized them based

Alterations in the proportion of T cell subpopulations are associated with brain structural abnormalities in patents with schizophrenia with tardive dyskinesia (TD), according to a study published in the July issue of Schizophrenia Research.Na Li, from the Peking University HuiLongGuan Clinical Medical School in Beijing, and colleague

Specific body composition patterns are associated with neurodegenerative diseases and brain aging, according to a study published online July 24 in Neurology.Shishi Xu, M.D., Ph.D., from the West China Hospital of Sichuan University in Chengdu, and colleagues conducted a retrospective analysis using data from the U.K. Biobank to exam

Hospitals and clinical laboratories across the United States are facing a critical shortage of bottles used to culture blood samples, federal health officials report.Without the ability to culture blood, patients might receive the wrong antibiotics to treat conditions like <a href="https://my.clevelandclinic.org/health/diseases/16957-endocard

Arizona health officials are reporting an increase in hantavirus infections, which are spread by rodents and can cause severe respiratory illness.In a recent health alert, the Arizona Department of Health Service

Many breast cancer survivors with indications for genetic counseling and testing do not receive it, according to a study published online July 15 in the&nbsp;Journal of Clinical Oncology.Steven J. Katz, M.D., from the University of Michigan in Ann Arbor, and colleagues examined receipt of genetic testing and communication with relative

Screening with fecal immunochemical tests (FITs) lowers the risk of dying from colorectal cancer (CRC), according to a study published online July 19 in&nbsp;JAMA Network Open.Chyke A. Doubeni, M.D., from The Ohio State University College of Medicine in Columbus, and colleagues evaluated whether FIT screening is associated with a lower

A joint artificial intelligence (AI)-assisted model integrating clinical information and endoscopic ultrasonographic (EUS) images improves diagnosis of solid lesions in the pancreas, according to a study published online July 19 in JAMA Network Open.Haochen Cui, M.D., from Tongji Hospital in Wuhan, China, and colleagues developed a mult

At least 28 people have been hospitalized and two have died in a multi-state outbreak of listeria linked to deli meat, U.S. health officials warned.In an&nbsp;investigation notice posted Friday, the U.S. Centers for Disease Control and Prevention said the true number

Expression of several stress-related genes in prostate tumors is elevated among men residing in disadvantaged neighborhoods, according to a study published online July 12 in JAMA Network Open.Joseph Boyle, Ph.D., from Virginia Commonwealth University in Richmond, and colleagues examined whether several neighborhood disadvantage metrics

A German man has become the seventh person to apparently be cured of HIV, researchers report.The 60-year-old man, referred to as the “next Berlin Patient,” was treated with a stem cell transplant in October 2015 for acute myeloid leukemia, researchers said.He stopped taking the antiretroviral drugs needed to suppress HIV in September 2018

Multiple substantia nigra (SN) pathologies are associated with parkinsonism, according to a study published online July 15 in JAMA Neurology.Jason W. Adams, Ph.D., from the Boston University Alzheimer's Disease and CTE Center, and colleagues examined the frequency of parkinsonism in individuals with chronic traumatic encephalopathy (CT

An estimated 40.0 percent of all incident cancer cases and 44.0 percent of cancer deaths are attributable to potentially modifiable risk factors among U.S. adults aged 30 years and older, according to a study published online July 11 in CA: A Cancer Journal for Clinicians.Farhad Islami, M.D., Ph.D., from the American Cancer Society in A

For patients with private insurance undergoing diagnostic testing after prostate-specific antigen (PSA)-based screening, out-of-pocket costs are considerable and increased from 2010 to 2020, according to a study published online July 15 in Cancer.Arnav Srivastava, M.D., M.P.H., from the University of Michigan in Ann Arbor, and colleague

Five poultry workers in Colorado have been diagnosed with bird flu, state health officials reported Sunday."In coordination with the Colorado Department of Agriculture, the State Emergency Operations Center and Centers for Disease Control and Prevention, the Colorado Department of Public Health and Environment [CDPHE] is now reporting a total of

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

Tampon use is a potential source of metal exposure, according to a study published in the August issue of Environmental International.Jenni A. Shearston, Ph.D., from the School of Public Health at the University of California Berkeley, and colleagues compared the concentrations of 16 metal(loid)s (arsenic, barium, calcium, cadmium, co

Lupus is caused by a specific defect in the immune system that can be reversed, potentially curing the autoimmune disorder, a new study claims.The disease appears to be caused by malfunctions in an immune system pathway that regulates cells’ response to environmental pollutants, bacteria and toxins.Insufficient activation of this pathwa

Anorexia nervosa could be caused by lack of a specific brain chemical, reports a research team that has developed a possible cure for the eating disorder.Mouse studies have revealed that a deficit in acetylcholine, a neurotra

Colorado health officials on Tuesday confirmed a case of human plague in that state.The infection -- which occurred in Pueblo County, in the southern part of the state -- was&nbsp;first reported&nbsp;Friday ba

Few Americans understand the health risks of drinking raw milk, a new survey shows, so experts are redoubling efforts to get the word out on its dangers.The push dovetails with the discovery this spring of bird flu virus in milk from infected cows. The H5N1 virus is widespread in wild birds worldwide and is causing outbreaks in poultry and U.

During 2023, there were increases in the incidences of certain foodborne disease, which may reflect changes in diagnostic practices, according to research published in the July 4 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Hazel J. Shah, M.P.H., from the CDC in Atlanta, and colleague

In a trial involving patients with therapy-refractory cancer treated with approved targeted or immunotherapies, matched to their tumor molecular profile but outside their registered indications, those for whom a waiver was granted had similar serious adverse event rates and clinical benefit rates as those who did not receive a waiver, according to a stu

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

Amid an ongoing outbreak of bird flu in dairy cows, a fourth case of H5N1 avian flu has been confirmed in another dairy worker, U.S. health officials reported Wednesday.The latest case was reported in Colorado, the U.S. Centers for Disease Control and Prevention said in a news release."As with previous cases, the person is a worker on a

U.S. health officials announced Tuesday that the federal government will pay Moderna $176 million to speed development of a pandemic flu vaccine based on mRNA technology.Such a vaccine could be used to treat bird flu in people, as concern grows about&nbsp;H5N1 cases spreading in dairy cows&nbsp;across the country, the U.S. Department of Health a

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

For individuals with Alzheimer disease (AD), the emergence of psychosis is associated with elevations in levels of plasma tau phosphorylated at threonine 181 (p-tau181), according to a study published online June 26 in JAMA Psychiatry.Jesus J. Gomar, Ph.D., and Jeremy Koppel, M.D., from the Feinstein Institutes for Medical Research in Ma

As bird flu continues to spread among U.S. dairy cows, reassuring new government research finds the pasteurization process widely used in the industry effectively kills all bird flu virus in milk.In a health update&nbsp;poste

The spread of H5N1 avian flu to dairy cows has health experts and many Americans on edge, and now a new study finds the virus stays viable on milking equipment for at least an hour.“Dairy cows have to be milked even if they are sick, and it has not been clear for how long the virus contained in residual milk from the milking process remains stab

Rare predicted loss-of-function (pLOF) variants and a polygenic risk score (PRS) are associated with increased atrial fibrillation (AF) risk, according to a study published online June 26 in JAMA Cardiology.Oliver B. Vad, M.D., from Copenhagen University Hospital–Rigshospitalet in Denmark, and colleagues examined rare pLOF variants as

The gut microbiome has a potential functional role in the pathogenesis of type 2 diabetes (T2D), according to a study published online June 25 in Nature Medicine.Zhendong Mei, Ph.D., from Brigham and Women's Hospital in Boston, and colleagues analyzed 8,117 shotgun metagenomes from 10 cohorts of individuals with T2D, prediabetes, and

The cumulative risk for advanced gastric cancer varies from 6.5 to 10.3 percent for carriers of germline CDH1 pathogenic/likely pathogenic (P/LP) variants, according to a study published online June 14 in the Journal of the American Medical Association to coincide with presentation at the International Gastric Cancer Linkage Consortiu

Cognitive impairment is delayed among persons who are heterozygous for the apolipoprotein E3 Christchurch variant (APOE3Ch), according to a study published in the June 20 issue of the New England Journal of Medicine.Yakeel T. Quiroz, Ph.D., from Massachusetts General Hospital in Boston, and colleagues analyzed data

A deadly bacterial infection known as streptococcal toxic shock syndrome (STSS) is spreading across Japan, officials in that country report.In March, Japan's National Institute of Infectious Diseases issued its first warning&nbs

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

Past-year Papanicolaou testing rates were lower in 2022 than in 2019, overall, and lower rates were seen in rural versus urban women, according to a study published in online June 14 in JAMA Network Open.Tyrone F. Borders, Ph.D., and Amanda Thaxton Wiggins, Ph.D., from the University of Kentucky in Lexington, examined receipt of a Papan

Second tumors are rarely seen after chimeric antigen receptor (CAR) T-cell therapy, according to a study published in the June 13 issue of the New England Journal of Medicine.Mark P. Hamilton, M.D., Ph.D., from Stanford University in California, and colleagues examined the occurrence of second tumors after CAR T-cell therapy since 2016.

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

Select patients with progressive multiple sclerosis (MS) may benefit from mesenchymal stem cell-neural progenitors (MSC-NPs), according to a study published online May 23 in Stem Cell Research &amp; Therapy.Violaine K. Harris, Ph.D., from the Tisch Multiple Sclerosis Research Center of New York in New York City, and colleagues conduct

Generation X is experiencing larger per-capita increases in the incidence of cancers than Baby Boomers, according to a study published online June 10 in JAMA Network Open.Philip S. Rosenberg, Ph.D., and Adalberto Miranda-Filho, Ph.D., from the National Cancer Institute in Bethesda, Maryland, estimated invasive cancer incidence trends

A U.S. Food and Drug Administration advisory panel voted unanimously on Monday to recommend that the benefits of a new drug for Alzheimer's outweigh its harms, which can include brain swelling and bleeding.Eli Lilly's donanemab did slow declines in thinking skills in patients with early-stage Alzheimer's: <a href="https://www.fda.gov/media/1791

A novel blood-based lung cancer screening test has been developed and validated using genome-wide sequencing to analyze cell-free DNA (cfDNA) fragmentation profiles, according to a study published online June 3 in Cancer Discovery.Noting that changes in genome-wide cfDNA fragmentation profiles (fragmentomes) in peripheral blood reflect

Higher county-level prevalence of prostate-specific antigen (PSA) screening is associated with lower odds of advanced disease, all-cause mortality, and prostate cancer-specific mortality, according to a study published online June 4 in&nbsp;JAMA Network Open.Hari S. Iyer, Sc.D., from Rutgers Cancer Institute of New Jersey in New Brunswic

The U.S. Food and Drug Administration on Thursday asked states to work harder to protect the public from the risks of raw milk as a bird flu outbreak continues to spread among dairy cows.In an open letter to state and local officials,&nbsp;the agency urged more testing of&nbsp;her

Anthrax disease in humans is rare and when it does occur, it's usually during hot, dry summers.That's why the case of a Texas rancher who developed anthrax in January of this year piqued the interest of investigators at the U.S. Centers for Disease Control and Prevention.The rancher, who survived his ordeal, caught the anthrax germ after b

Lowering the fecal immunochemical test (FIT) positive threshold yields levels of sensitivity and specificity that are comparable to those reported for multitarget stool RNA (mt-sRNA) testing without the additional testing, according to a research letter published online June 1 in the Journal of the American Medical Association.Tobias

Excess mortality persisted in 2020 through 2022 in the Western world, according to a study published online June 3 in BMJ Public Health.Saskia Mostert, M.D., from Amsterdam UMC, and colleagues explored excess mortality in the Western world from 2020 to 2022 using all-cause mortality reports abstracted from the "Our World in Data" databa

As the H5N1 avian flu continues to spread among dairy cows in the United States, nearly 5 million doses of flu vaccine are now being prepared for possible use in humans.Since the outbreak in livestock began this spring, bird flu has been confirmed in three humans who worked on dairy farms in Texas and Michigan, and health experts are concerned th

Amid an ongoing outbreak of bird flu in dairy cows, there's been a third case of H5N1 avian flu confirmed in a dairy worker, U.S. health officials reported Thursday.The previous two human cases -- the first in Texas, the second in Michigan, where this latest case also occurred -- involved only a brief discomfort of the eyes, linked to conjuncti

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Bird flu has been detected for the first time in alpacas, the U.S. Department of Agriculture (USDA) announced Tuesday.The animals that tested positive were on a farm in Idaho where poultry that had tested positive for the H5N1 virus were culled in May.&nbsp;The alpacas tested positive on May 16, the USDA's National Veterinary Services Laborato

A novel natural language understanding (NLU) pipeline can identify the rates of lymphedema and node positivity among women with estrogen receptor-positive (ER+), clinically node-negative (cN0) breast cancer, according to a study published online May 22 in JCO Clinical Cancer Informatics.Neil Carleton, from the UPMC Hillman Cancer Center

Primary human papillomavirus (HPV) screening intervals could be extended, with the risk for cervical precancer or worse (CIN2+) eight years after negative HPV screening comparable to risk after three years in cytology cohorts, according to a study published online May 22 in Cancer Epidemiology, Biomarkers &amp; Prevention.Anna Gottschlic

A U.S. Food and Drug Administration advisory panel on Thursday recommended the approval of a new blood test that can spot colon cancer.The panel voted 7-2 that the benefits outweigh the risks when using the Guardant Health's Shield test for&nbsp;colon cancer</a

Variation is seen in preparedness and response to highly pathogenic avian influenza (HPAI) A(H5N1) viruses, according to a research letter published online May 21 in the Journal of the American Medical Association.Noting that HPAI A(H5N1) clade 2.3.4.4b viruses pose pandemic potential, Noah Kojima, M.D., from the U.S. Centers for Diseas

In a systematically screened population, there is no association between autoimmune disease and monoclonal gammopathy of undetermined significance (MGUS), according to a study published online May 21 in the Annals of Internal Medicine.Ingigerdur Sverrisdottir, M.D., from the University of Iceland in Reykjavik, and colleagues conducted a

Individuals with BRCA1-associated protein (BAP1) have a high rate of nail abnormalities consistent with onychopapillomas, according to a study published online May 17 in JAMA Dermatology to coincide the annual meeting of the Society for Investigative Dermatology, held from May 15 to 18 in Dallas.Alexandra Lebensohn, from the Nat

There is a high level of approval for use of polygenic embryo screening, according to a study published online May 14 in JAMA Network Open.Rémy A. Furrer, Ph.D., from the Center for Bioethics at Harvard Medical School in Boston, and colleagues surveyed U.S. adults to examine general attitudes, interests, and concerns relating to use of P

Male and female V1421 carriers face a similar and substantial risk for heart failure hospitalization, according to a study published online May 12 in the Journal of the American Medical Association to coincide with the European Society of Cardiology Heart Failure 2024, held from May 11 to 14 in Lisbon, Portugal.Noting that individual s

Non-Hispanic Black (NHB) melanoma patients have distinct tumor characteristics, presenting with more advanced disease and exhibiting worse outcomes, according to a study published in the May issue of the Journal of Surgical Oncology.Jessica A. Steadman, M.B.B.S., from the Mayo Clinic in Rochester, Minnesota, and colleagues examined fe

In its biennial Cancer Disparities Progress Report published today, the American Association for Cancer Research presents the latest statistics on disparities in cancer progress experienced by ethnic-minority groups and other medically underserved populations in the United States.Robert A. Winn, M.D., from the Virginia Commonwealth Un

The U.S. Food and Drug Administration has approved a kit that will allow women to collect their own vaginal sample for HPV screening, a move that could increase early detection in those at risk for cervical cancer.Women will be able to swab thems

San Francisco is on the verge of passing a ban on "forever chemicals" in the protective clothing firefighters wear while battling blazes.City lawmakers are expected to pass an ordinance on Tuesday&nbsp

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

The U.S. Department of Agriculture and U.S. Department of Health &amp; Human Services have jointly announced a myriad of initiatives aimed at preventing the H5N1 avian flu virus, currently infecting U.S. dairy cows, from mutating and spreading in humans.The illness is typically not fatal in bovines, but monitoring and prevention on the nation's f

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

A total of 113 novel genetic loci have been identified in the largest single-stage common variant genome-wide association study of blood pressure (BP) reported to date, according to a study published online April 30 in Nature Genetics.Jacob M. Keaton, Ph.D., from the National Institutes of Health in Bethesda, Maryland, and colleagues exa

Hematopoietic cell transplantation (HCT) use has increased among all racial/ethnic groups and has increased faster among non-Hispanic African Americans (NHAAs) and Hispanics than non-Hispanic Whites (NHWs), according to a study published online April 25 in Blood Advances.Nandita Khera, M.D., from the Mayo Clinic in Phoenix, and colleagues

CD7 expression is associated with poorer outcomes in patients with newly diagnosed acute myeloid leukemia (AML), according to a study published online April 11 in the British Journal of Haematology.Wei-Ying Jen, B.M., B.Ch., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues collected flow cytometry data on

Doctors in Texas are describing the only known human case of H5N1 avian flu connected to the ongoing outbreak of the disease in dairy cows.Bird flu in humans remains extremely rare, but in the hundreds of cases documented worldwide over the past few years, about half proved fatal -- upping scientists' concerns about the possibility that an easily

A genome-wide association study meta-analysis, published online April 26 in Nature Genetics, has identified 63 susceptibility regions containing 108 independent risk loci for kidney cancer.Mark P. Purdue, Ph.D., from the National Cancer Institute in Rockville, Maryland, and colleagues conducted a multi-ancestry genome-wide association s