All articles tagged: Clinical Summary

Higher consumption of ultraprocessed foods, such as carbonated drinks, processed meats, and sweet or savory packaged snacks, is associated with accelerated biological aging.

Even though adding HPSA testing to a colon cancer screening program did not reduce the incidence or mortality rates of gastric cancer, potential benefits were still observed.

Sleep-related daytime dysfunction was linked to increased risk for motoric cognitive risk syndrome in older adults.

In a cohort study, patients who underwent ultrasonography-guided nerve blocks in the emergency department experienced a complication rate of 0.4%, with one major and nine minor adverse events.

Combining magnetic and direct current transcranial stimulations was more effective than either treatment alone for major depressive disorder.

Dermatologic adverse events affected 97.8% of pediatric patients on MEK inhibitors, in a small retrospective single-center study.

Sedentary time exceeding 10.6 h/d was associated with a higher risk for heart failure and cardiovascular mortality in a new study.

Using home spirometry for the management of systemic sclerosis–associated ILD can enhance the ability to detect pulmonary decline early, leading to better patient care and outcomes.

Early implementation of treatment with biologic or targeted synthetic DMARDs after methotrexate failure did not prevent the development of difficult-to-treat RA in patients with early RA.

A study found that GLP-1 RA use is linked to risks for retained gastric contents during single endoscopic procedures but not with combined upper endoscopy and colonoscopy.

Newer themes prioritised among "top 10" included the use of artificial intelligence, provision of holistic care, access to newer therapies, and women's health.

The rising incidence of pancreatic cancer among young Americans may largely reflect previously undetected cases not a true rise in occurrence, experts say.

Light-intensity walking reduced postprandial glucose and diastolic blood pressure in young adults with obesity.

The use of SGLT2 inhibitors for the treatment of heart failure rose in the United States, particularly among younger patients, those with mildly reduced ejection fraction, and Medicaid recipients.

Diets with more plant-based protein are likely to be safe for adults aged over 65, except for a vegan scenario that failed to provide enough protein in most people, a simulation study found.

Intermittent calorie restriction followed for 2 nonconsecutive days per week reduced the liver fat content in patients with MASLD more effectively than the standard diet.

Aggressive infliximab dosing did not provide additional clinical benefits for patients with steroid-refractory acute severe ulcerative colitis compared with standard dosing.

Initiating biologic therapy early in order to achieve transmural healing led to better long-term outcomes in patients with Crohn's disease.

Brief cognitive behavioral therapy delivered via video telehealth reduced suicide attempts among adults with recent suicidal thoughts and/or behaviors.

Among four approaches, perioperative chemotherapy and trimodality therapy were associated with better survival outcomes in locally advanced esophageal cancer.

Physical activity, even at low intensity, was associated with a significantly lower risk for mortality in patients with dementia.

For colorectal cancer screening, colonoscopy and stool tests are more effective and less costly than novel first-generation blood tests, a modeling study has found.

Vitamin D supplementation decreased blood pressure in older individuals with overweight, according to a post hoc analysis of a randomized controlled trial.

Researchers analyzed data from a cohort study of 1251 patients with advanced-stage nasopharyngeal cancer, of which 202 were statin users.

A new study found a modest reduction in unnecessary antibiotic prescriptions for community-acquired infections following a multifaceted intervention.

Children who underwent multiple exposures to anesthesia before age 5 had lower IQ scores, especially in verbal and perceptual skills, and an increase in maladaptive behaviors, a new study found.

A new study highlighted the need to monitor long-term variability in blood pressure and mean blood pressure alongside intraocular pressure to prevent visual field progression in patients with glaucoma.

An 8-year study found an increased incidence of diverticulitis in EDs in the United States, along with increased CT usage, fewer admissions, and a shift to penicillin-based antibiotics for treatment.

Increasingly, the burden falls on low- and middle-income countries.

Women with PCOS have longer interconception periods, are of advanced maternal age, and have higher nulliparity and lower fecundity than women without PCOS.

In hospitalized patients, eosinophil levels positively correlated with antibiotic use, systemic inflammation, and worsened outcomes.

Increased exposure to fine particulate matter during pregnancy significantly increased the likelihood of having a spontaneous preterm birth, notably influenced by socioeconomic and environmental conditions.

Evidence-based smoking cessation treatment within 6 months of a cancer diagnosis yielded the largest survival benefit, according to a prospective cohort study.

In a cohort study in the United States, high rates of emergency department visits during pregnancy were associated with an increased risk for severe maternal morbidity at the time of birth.

If current trends continue, more than 250 million Americans will have overweight or obesity in the next quarter-century.

Adults and children with noninfectious uveitis had lower health-related quality of life than those without the condition, a new meta-analysis found.

A retrospective cohort study revealed that breast cancer survivors who carry BRCA1/BRCA2 germline variants have an increased risk for second primary cancers.

Workplace violence was found to be common and underreported among healthcare workers, especially nurses and younger staff in urban EDs, with incidents often involving gender- or race-related bias.

A case series characterized wounds associated with xylazine exposure, an increasingly common adulterant found in illicitly manufactured fentanyl in the United States.

A cross-sectional study found the prevalence of idiopathic intracranial hypertension among women in the United States varied significantly by state.

Patients with endogenous Cushing syndrome faced an increased risk for glaucoma at a younger age than is typical for the eye disorder, a retrospective analysis found.

Only six physicians were disciplined for misleading the public in five biggest US states, a new study showed.

Early detection of atrial arrhythmias may prevent strokes in sickle cell disease.

Modafinil and cognitive behavioral therapy, either alone or in combination, were associated with significantly less fatigue in patients with multiple sclerosis.

Researchers examined the relationship between US county mean PM2.5 levels and head and neck cancer (HNC) incidence rates.

Cardiac arrest survivors with complete neurologic recovery had significantly higher 5-year survival rates than those with moderate or severe neurologic disabilities, found a study.

Modularity optimization outperformed Dartmouth Health Referral Regions in accurately defining emergency general surgery care regions, found a cross-sectional study.

Adults with hypoparathyroidism treated with TransCon PTH in the phase 3 PaTHway open-label trial extension demonstrated sustained efficacy, safety, and tolerability in a 1-year analysis.

No adverse events related to vitamin K use were identified, indicating a good safety profile for the supplementation.

A multicenter study found that the timing of radiotherapy after radical prostatectomy did not significantly affect patients' long-term health-related quality-of-life outcomes.

Low-dose oral minoxidil did not have a significant effect on blood pressure in patients being treated for alopecia, although it increased heart rate slightly, according to a systematic review and meta-analysis.

A large cross-sectional study revealed that late-onset axial spondyloarthritis diagnosed after 45 years of age may represent a distinct phenotype from early-onset axial spondyloarthritis.

COVID-19 infection increased the risk for autoimmune blistering diseases, but vaccination had protective effects, according to the results of a retrospective cohort study.

Children with antineutrophil cytoplasmic antibody–associated vasculitis had similar remissions rates with rituximab and cyclophosphamide in an international registry-based study.

Patients with cancer screening positive for financial distress received one-on-one consultations with trained financial navigators.

Heat waves were associated with increased adverse events among individuals older than 65 years with both Medicare and Medicaid coverage; higher mortality rates were observed during heat wave days vs non–heat wave days.

In addition to its effect on reducing Demodex in patients with rosacea, topical ivermectin may improve symptoms by changing the skin microbiome.

A retrospective cohort study using data from patients in 21 countries showed use of semaglutide use was not linked to an increased risk for nonarteritic anterior ischemic optic neuropathy.

Alterations in the gut microbiome began as early as 10 months before the onset of RA in anticyclic citrullinated protein–positive individuals at a risk of developing the condition, a study found.

Researchers looked for associations of plasma omega-3 and omega-6 polyunsaturated fatty acids with the incidence of cancer.

Phase 3 study on previously untreated chronic lymphocytic leukemia showed sustained PFS with venetoclax-obinutuzumab.

Postpartum exercise was associated with a 45% reduction in the odds of developing depression.

Study suggested that greater practice-level telehealth use was not associated with the delivery of low-value care services in primary care.

Researchers conducted a cohort study to try to characterize long-term treatment-related adverse effects and complications in patients treated for prostate cancer.

Genetic testing of patients with inherited retinal diseases may be less likely to turn up a conclusive diagnosis for certain racial groups, according to new research.

About 1 in 6 women were found to experience symptoms of postpartum depression 2 months after cesarean delivery.

A phospholipid nanoemulsion–based ocular lubricant improved the stability of tear film and alleviated the symptoms of dry eye disease, a new study found.

Levonorgestrel IUDs were associated with increased risks for acne, alopecia, and hirsutism in a study of FDA adverse event reports.

Both infliximab and adalimumab were found to be effective in achieving remission and enhancing quality of life while having a high level of tolerability in patients with mucocutaneous Behçet syndrome.

The risk for breast induration was associated with the irradiated breast volume in patients aged 65 years or older; smoking doubled the risk for induration irrespective of irradiated volume and age.

FDA-approved software is improving visual acuity for children with amblyopia in a real-world registry, including older youth and those who have received prior treatment for the condition.

The rate of HCV reinfection was high in the immediate posttreatment period among individuals who injected drugs but decreased significantly over time.

A meta-analysis found no association between cardiovascular events and the commonly used gastric acid suppressants, despite a relatively higher rate of this adverse event in trials of reflux disease.

AI-assisted colonoscopy improved adenoma detection compared with routine colonoscopy, regardless of the endoscopist’s experience, technology system, or healthcare setting.

Patients with cancer receiving immune checkpoint inhibitors had a twofold higher risk of developing psoriasis than those receiving chemotherapy or targeted therapy, according to the results of a cohort study.

Sugar restriction during pregnancy and in early childhood delayed the onset of type 2 diabetes and hypertension by about 4 and 2 years, respectively, found a natural experiment in sugar rationing.

Central obesity increased the risk for pelvic organ prolapse by around 50%, regardless of BMI.

The propofol-ketamine combination significantly reduced the incidence of sedation-induced atelectasis and allowed faster emergence from anesthesia than propofol alone in children undergoing MRI.

A diverse, real-world patient population with triple-negative breast cancer that received pembrolizumab showed similar overall rates of immune-related adverse events.

Researchers studied how patient location impacts access to healthcare by comparing travel times across various types of care to identify patient travel patterns and evaluate market definitions.

In all, 66% of postpartum women say they are frustrated with their sex life.

The survey found that two thirds of patients do not adhere, and half say postponing breakfast was burdensome for them.

The interaction between the gut microbiome and metabolites may mediate the effects of exposure to per- and polyfluoroalkyl substances on reduced kidney function in young adults.

Despite increased imaging referrals, AI-based diabetic retinopathy detection systems have not gained traction in the United States, with traditional methods still dominant.

Weight loss from behavioral changes or medication can improve glycemic control and increase menstrual frequency in polycystic ovary syndrome, a new meta-analysis showed.

A 12-year study reported over 72 million patient visits for superficial cutaneous fungal infections in the United States.

Wearing a face mask during intravitreal anti-VEGF injections was associated with higher odds for endophthalmitis, according to a study of more than a million injections.

A combination of metformin and topiramate along with a low-calorie diet was an effective, low-cost weight loss strategy in women with polycystic ovary syndrome.

Residential exposure to fine particulate matter, nitrogen dioxide, and black carbon are positively linked to lung cancer incidence and mortality.

A dietary intervention restored kidney function in animal studies and in a pilot study of patients with chronic kidney disease.

Patients with cancer participating in the Medicare Low-Income Subsidy program were less likely to receive systemic therapy at all, a new analysis suggests.

Weekend exercise is associated with a reduced risk for mild dementia, suggesting that even limited physical activity may offer protective cognitive benefits.

Back pain and the back-related function improved significantly in the virtual yoga group at 12 weeks and 24 weeks compared to the control group.

Surveillance data showed numbers "well above" the 5-year average, even ahead of the winter peak.

Intravenous methylprednisolone is not significantly beneficial vs oral glucocorticoids in improving visual acuity or survival in patients with giant cell arteritis, and it increases diabetes risk.

Between 2011 and 2023, the FDA reported 334 voluntary recalls of cosmetic dermatology products, mostly because of microbial contamination, according to an analysis of an FDA database.

An analysis of a large population of commercially insured children with juvenile idiopathic arthritis in the US showed an increasing popularity of more targeted therapies over the past two decades.

In univariate analysis, vitamin D deficiency was associated with younger age, Black race, female sex, and higher obstructive Apnea-Hypopnea Index.

Researchers compared the risks for distant metastases between patients with local regrowth after watch and wait and those with near-complete pathologic response managed by total mesorectal excision.

Autism diagnoses surged by 175% in the United States from 2011 to 2022, with the greatest relative increases in young adults, women, and children in multiple racial and ethnic groups.

Fidanacogene elaparvovec gene therapy may usher in a new era in the treatment of hemophilia B.

Patients with unresectable locally advanced or metastatic HER2+ breast cancer were randomly assigned to receive trastuzumab duocarmazine or a physician’s choice.

In a phase 2 trial, iberdomide was associated with improved symptoms when added to standard lupus medications in patients with subacute and chronic cutaneous lupus erythematosus

Compared with the general population, patients with erythropoietic protoporphyria have notably lower bone mineral density, although it improved with cholecalciferol supplementation.

Sleep issues in early midlife are associated with accelerated brain aging among middle-aged adults, a new study shows.

Early bilirubin screening could identify 83% of neonates needing phototherapy within 24 hours of birth, a new study found.

The treatment-related adverse events, however, were higher with the radiotherapy-TKI combination among patients with oligometastatic NSCLC.

Hearing loss was associated with an increased risk for Parkinson’s disease over 10 years, but early use of hearing aids reduced this risk, a new study shows.

Despite long-standing warnings, older patients with stroke continue to receive excessive prescriptions for benzodiazepine after discharge in the United States, a new study found.

Female physicians and nonphysicians had similar live birth rates per embryo transfer.

A recent study revealed a significant increase in emergency department visits both before and after a diagnosis of incident dementia among Medicare beneficiaries in the United States.

Those diagnosed with type 2 diabetes when younger than 40 years of age had greater risks for several diabetes-related outcomes.

Opioid use and misuse have negative effects on the endocrine system and can lead to hypothalamic-pituitary system and bone health complications.

Maternal eating disorders and high BMI were strongly associated with offspring who had sleep disorders, social functioning and tic disorders, and intellectual disabilities.

A subgroup analysis found that pembrolizumab plus chemotherapy improved disease-free survival in high-risk patients with endometrial cancer and dMMR tumors.

Allogeneic bone marrow–derived mesenchymal stromal cells were safe but did not demonstrate efficacy in treating intervertebral disc degeneration in patients with chronic low back pain.

Researchers aimed to evaluate the efficacy of combining atezolizumab with targeted therapy based on tumor mutation status.

Removing screen time in the hour before bedtime was feasible and showed modest preliminary benefits for sleep.

The long-acting formulation of fluticasone propionate utilizing extended-release technology may offer a longer duration of pain relief than vehicle control in patients with knee osteoarthritis.

A post-STOP era analysis showed increasing stroke rates among Californians with sickle cell disease.

An analysis of three phase 3 trials reported relief with upadacitinib through 76 weeks in adolescents with AD.

A study found a 247% rise in mountain biking–related fractures in the United States from 2019 to 2020; the upper extremities were most affected, with the highest risk seen among adult men.

The elusive but correct diagnosis proved to be a simple, easily treated condition.

Landiolol reduced and maintained heart rate without increasing the need for vasopressors in the first 24 hours in patients with septic shock and persistent tachycardia, a trial found.

Taking a GLP-1 receptor agonist was associated with a lower risk for cirrhosis and related complications in patients with metabolic dysfunction–associated steatotic liver disease and diabetes.

A recent study found that older Black adults with breast cancer were less likely to receive timely, guideline-concordant care than White adults.

High-intensity exercise may be more effective than moderate-intensity exercise in suppressing ghrelin levels and modifying hunger, with women showing the most response.

An analysis of over 400,000 patients with T1D revealed a rise in prescribing for glucagon-like peptide 1 receptor agonists and sodium-glucose cotransporter 2 inhibitors over the past decade.

Air pollution, specifically fine particulate matter ≤ 2.5 μm, was associated with an increased risk for breast cancer, particularly among White women.

Oral semaglutide improved liver health, diabetes status, and lipid profile in patients with MASLD and T2D, with weight loss likely playing a role, showed a prospective study.

Levonorgestrel-releasing intrauterine systems, like other hormonal contraceptives, are associated with an increased risk for breast cancer, Danish researchers have found.

A study found significant disparities in mortality due to cardiac arrest and patient disposition across age groups, races, and socioeconomic statuses in US emergency departments between 2016 and 2020.

Video laryngoscopy showed a higher first-attempt success rate than direct laryngoscopy for emergency tracheal intubation in critically ill patients under hospital settings, found a new trial.

A greater proportion of women in the intervention group reported tolerable pain during placement and expressed a willingness to choose IUD as contraception again.

Researchers analyzed US-based phase 1-3 cancer treatment trials registered on ClinicalTrials.gov from 2017 to 2022.

Participants were randomly assigned to receive either three or six cycles of CEV chemotherapy after enucleation.

Researchers conducted a retrospective analysis to identify the specific population of patients with TNBC that benefited from adjuvant capecitabine.

Dry eye disease was associated with a higher risk for mental health problems in a diverse nationwide population of American adults, with a particularly higher prevalence among Black Americans.

More than 90% of patients with PsA who received guselkumab every 8 weeks in the DISCOVER-2 trial maintained minimal clinically important improvement in joint symptoms through week 52.

Up to 100% of ritlecitinib responders sustained hair regrowth and 30% of nonresponders achieved results at week 48 with continuous treatment, according to a post hoc study analysis.

The findings suggested that higher doses of vitamin D3 supplementation do not reduce markers of subclinical cardiovascular disease in older adults with low serum vitamin D levels.

More than half of US contraceptive users preferred alternative sources over traditional in-person care.

A single 30-minute session of aerobic exercise led to improved glucose metabolism and insulin sensitivity in healthy young adults 1 day later.

A fracture risk assessment tool that factors in bone mineral density predicted the risk for incident major osteoporotic fractures and hip fractures in patients with cancer.

A meta-analysis found substantial demographic and geographic disparities in glaucoma burden in the United States.

Nearly one in five adolescent girls with PCOS have high blood pressure, a new study found.

A new study aimed to examine associations between dietary patterns and survival among Black women diagnosed with epithelial ovarian cancer.

In the first randomized controlled trial in patients with vestibular migraine, galcanezumab outperformed placebo in reducing dizziness.

Continuing metformin after bariatric surgery did not provide additional benefits for glycemic control or weight reduction in patients with obesity and type 2 diabetes, a retrospective study found.

Mothers with HS and their children face higher risks for adverse outcomes at birth and long-term, a study found.

Older adults with metastatic cancer living in Mexico experience a high time toxicity burden, spending about 21% of their days with healthcare contact.

Exposure to conversion practices targeting gender identity, sexual orientation, or both is associated with increased mental health symptoms in sexual and gender minorities.

Stereotactic body radiotherapy was associated with significantly better urinary continence and fewer sexual issues at 2 years than prostatectomy in patients with localized prostate cancer.

The rate of laypeople giving naloxone to those who were overdosing increased over a 2-year period but was still small compared with EMS-administered use of the reversal drug, according to a new study.

Patients with neovascular age-related macular degeneration diagnosed by a primary care clinician may be more likely to miss anti-VEGF treatments.

In a prospective cohort study, in utero exposure to COVID-19 was not associated with abnormal neurodevelopment in children up to 2 years of age.

In a prospective cohort study, in utero exposure to COVID-19 was not associated with abnormal neurodevelopment in children up to 2 years of age.

MASLD in pediatric obesity was linked to an increased risk for youth-onset type 2 diabetes, especially in the presence of intermediate hyperglycemia.

The HLA-DRB1*01:03 allele was significantly associated with increased severity of ulcerative colitis, including higher rates of hospitalization, surgery, and corticosteroid use.

Researchers investigated whether induction chemotherapy improves PFS and OS in patients with locally advanced cervical cancer.

JAK inhibitors were found to be either marginally more effective or as effective as biologic DMARDs in reducing pain in patients with rheumatoid arthritis in clinical practice.

Among patients with ischemic stroke, women were found less likely than men to receive and adhere to guideline-directed management therapies, a real-world study found.

Men with localized prostate cancer were randomly assigned to receive either SBRT or control radiotherapy in a phase 3 trial.

Automated insulin delivery systems not only improved glycemic endpoints but also alleviated disease burden and enhanced quality of life in patients with diabetes, a meta-analysis showed.

Patients with abnormal small bowel transit in systemic sclerosis were more likely to be men and have severe cardiac involvement, higher mortality, and fewer sicca symptoms.

Hormone receptor stratification showed that differences in population-attributable risk fractions by body fat were only observed in hormone receptor–positive cases.

HS is associated with a genetic predisposition that may increase the risk for CAD and diabetes, driven by shared genetic factors and altered plasma proteomic profiles.

A meta-analysis of 14 studies found that serum levels of anti-BP180 autoantibody strongly correlated with the severity of bullous pemphigoid.

White patients have the highest incidence of second primary melanoma, while Black patients face the greatest relative risk, according to a study.

Participants with type 2 diabetes who stopped insulin after receiving the novel ReCET endoscopic procedure in combination with semaglutide maintained their initial response at 2 years.

Bright light therapy was associated with a significantly higher remission rate in patients with nonseasonal depressive disorders than other treatments.

Individuals at a high genetic risk for gout faced a significantly higher risk for cardiovascular disease than those at a lower genetic risk and would benefit from adhering to a healthy lifestyle.

In a cross-sectional study, about one third of adult survivors of childhood cancer reported clinically significant or high fear of cancer recurrence.

Deprescribing antihypertensive medications is associated with reduced cognitive decline among older residents of nursing homes, particularly those with dementia.

In patients with axial spondyloarthritis and a history of cardiovascular events, recurrent cardiovascular events were frequent, but exposure to a TNF inhibitor reduced the risk for these events.

Greater urinary calcium excretion was associated with reduced bone accrual in youth with type 1 diabetes, found an observational study.

Monitoring and supplementing maternal 25(OH) vitamin D levels in patients with lupus within the 40-59 ng/mL range are crucial while preventing excessive supplementation, this study suggested.

Nonoperative outpatient management of uncomplicated pediatric appendicitis was found to be feasible and safe, with shorter hospital stays and 12% recurrent cases requiring appendectomy within a year.

Levels of the biomarkers GFAP, UCH-L1, and MAP-2 spiked within 30 minutes of traumatic brain injury, with GFAP diagnosing intracranial lesions and predicting critical outcomes most accurately.

A Thoracic thoracic epidural analgesia is a viable option for chest wall surgery in adolescents, with manageable acute events, a retrospective study found.

A stapler that produces a straight gastric sleeve in one fire improved the efficiency and perioperative outcomes of laparoscopic sleeve gastrectomy, compared with sequential staple firing.

Researchers found intake of vitamins A and C, and iron, decreased over the previous two decades, with implications for maternal health and fetal development.

This systematic review of 70 studies highlighted the lack of a universally accepted definition for recurrence of differentiated thyroid cancer across different treatment categories.

Increasing green infrastructure in residential areas may greatly benefit individuals with T2D by mitigating harmful pollutants, according to a large prospective study conducted in China.

Only 13.4% immunocompromised adult US veterans younger than 50 years received the recombinant zoster vaccine by mid-2023, which reflected a lag in the adoption of revised national recommendations.

Alitretinoin netted a greater reduction in severity by 12 weeks, although differences were not significant thereafter.

Testing rates for mismatch repair and microsatellite instability among patients with CRC increased from 2012 to 2021, but variations by cancer stage and other factors still exist.

Adolescents at pediatric trauma centers were more likely to undergo screening for substance use if they were Black, American Indian, Hispanic, girls, covered by Medicaid, or uninsured.

Delays in cancer registration probably led to a major underestimation of the effectiveness of screening colonoscopy in reducing colorectal cancer risk in the controversial NordICC trial.

Study shows COVID-19 was associated with higher self-reported incidence of fatigue and other symptoms.

Major medical journals relied on peer reviewers who received more than $64 million in non-research payments between 2020 and 2022.

Both low and high folate levels were linked to an increased risk for congenital heart disease, with vitamin B12 deficiency and elevated homocysteine levels further exacerbating this risk.

Older cancer survivors who had overweight or obesity at the time of first diagnosis had a higher risk for second cancers, particularly obesity-related cancers.

Triglyceride and HDL cholesterol levels before thyroid cancer surgery, integrated with several pathologic factors, may help predict the recurrence rate of papillary thyroid cancer.

Previously ignored at-risk patient populations caught by mail-in sexually transmitted infection testing.

Evidence suggested causation in a study that controlled for multiple confounders.

The increase in fluconazole resistance and non-Candida albicans yeasts over 3 years may be related to empirical treatment of vulvovaginal candidiasis.

Continuous glucose monitoring enhanced by geriatric care principles reduced the duration of hypoglycemia without worsening glycemic control in older adults with T1D.

Epidermal necrolysis was associated with high rates of inhospital and post-discharge mortality in a French cohort study.

Using mifepristone to manage early pregnancy loss reduced the need for subsequent procedural management, and its use may decrease healthcare utilization and expenditures.