All articles tagged: Diabetes & Endocrinology

Bisphenol A (BPA) administration is associated with reduced peripheral insulin sensitivity among healthy adults, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.Adam Seal, Ph.D., from the California Polytechnic State University in San Luis Obispo, and collea

Inhaled insulin is associated with improved hemoglobin A1c (HbA1c) levels over 16 weeks among adults with type 1 diabetes when compared to usual care, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.Irl B. Hirsch, M.D., from the University of Washington in S

For patients with obesity-related heart failure with preserved ejection fraction (HFpEF), semaglutide reduces body weight to a greater extent in women but yields similar improvements in heart failure-related symptoms in men and women, according to a study published online June 23 in the Journal of the American College of Cardiology to coinc

Tirzepatide reduces the apnea-hypopnea index (AHI) among individuals with moderate-to-severe obstructive sleep apnea and obesity, according to a study published online June 21 in the New England Journal of Medicine to coincide with the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.At

The gut microbiome has a potential functional role in the pathogenesis of type 2 diabetes (T2D), according to a study published online June 25 in Nature Medicine.Zhendong Mei, Ph.D., from Brigham and Women's Hospital in Boston, and colleagues analyzed 8,117 shotgun metagenomes from 10 cohorts of individuals with T2D, prediabetes, and

Intermittent fasting may be a more effective intervention than drugs for people with early diabetes and either obesity or overweight, according to a study published online June 21 in JAMA Network Open.Lixin Guo, M.D., from the Chinese Academy of Medical Sciences in Beijing, and colleagues evaluated the effect of intermittent fasti

The U.S. Supreme Court announced Monday that it would hear a case on a Tennessee law that bans transgender minors from receiving certain medical treatments in that state.The banned treatments include puberty-blocking drugs or hormonal therapies.It's the

A 10-week acupuncture intervention significant reduces endocrine symptoms and hot flashes among women with breast cancer receiving endocrine therapy (ET), according to a study published online June 24 in Cancer.Weidong Lu, M.P.H., Ph.D., from the Dana Farber Cancer Institute in Boston, and colleagues enrolled 158 patients with stage 0 t

Glucose lowering by metformin is greater when given before enteral glucose among patients with type 2 diabetes controlled by metformin monotherapy, according to a study recently published in Diabetologia.Cong Xie, Ph.D., from the University of Adelaide in Australia, and colleagues studied 16 participants with type 2 diabetes that was re

Both the World Health Organization and Eli Lilly warned Thursday that consumers should avoid fake versions of weight-loss drugs that are circulating in numerous countries.The WHO warning said that the inter

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

For sedentary adults with obesity/overweight and metabolic impairments, the timing of moderate-to-vigorous physical activity (MVPA) is significant, with a beneficial effect on glucose homeostasis for accumulation of more MVPA in the evening, according to a study published online June 10 in Obesity.Antonio Clavero-Jimeno, from the Univ

The annual meeting of the Endocrine Society (ENDO 2024) was held from June 1 to 4 in Boston, attracting approximately 7,000 participants, including clinicians, academicians, allied health professionals, and others interested in endocrine and metabolic disorders. The conference highlighted recent advances in the diagnosis and

The type of educational institution attended is associated with multiple health outcomes in midlife, according to a study published online June 18 in the Journal of Epidemiology & Community Health.Keyao Deng, from University College London, and colleagues examined associations between the type of high school or university attende

Roux-en-Y gastric bypass (RYGB) is successful in achieving long-term sustained weight loss and diabetes remission, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.John Nguyen-Lee, M.D., from the Geisinger Medical Center in Danville, Pennsylva

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

Continuing metformin and adding insulin in early pregnancy does not significantly alter the risk for nonlive birth or live birth with congenital malformations compared with switching to insulin monotherapy, according to a study published online June 18 in the Annals of Internal Medicine.Yu-Han Chiu, M.D., Sc.D., from the Harvard T.H. C

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

Paternal use of metformin in monotherapy is not associated with an increased risk for major congenital malformations (MCMs), according to a study published online June 18 in the Annals of Internal Medicine.Ran S. Rotem, Sc.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues examined the association between p

From 1999 to 2020, diet quality improved among U.S. adults, according to a study published online June 18 in the Annals of Internal Medicine.Junxiu Liu, Ph.D., from the Icahn School of Medicine at Mount Sinai in New York City, and Dariush Mozaffarian, M.D., Dr.P.H., from Tufts University in Boston, examined trends in diet quality by rac

For adolescents with severe obesity, meal replacement therapy (MRT) plus financial incentives (FIs) yield a greater reduction in body mass index (BMI) and total body fat mass than MRT alone, according to a study published online June 17 in JAMA Pediatrics.Amy C. Gross, Ph.D., from the University of Minnesota Center for Pediatric Obesity

Bariatric surgery significantly decreases the conversion from prediabetes to type 2 diabetes, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.John Nguyen-Lee, M.D., from the Geisinger Medical Center in Danville, Pennsylvania, and colleagues eval

From 1990 to 2019, there was an increase in life expectancy in older people with type 1 diabetes mellitus (T1DM), according to a study published online June 12 in The BMJ.Kaijie Yang, from the First Hospital of China Medical University in Shenyang, and colleagues estimated the burden, trends, and inequalities of T1DM among older adults

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

Adverse social determinants of health (SDOH) are associated with higher prevalence of prediabetes among adolescents, according to a study published online June 11 in JAMA Network Open.Caleb Harrison, from the UPMC Children's Hospital of Pittsburgh, and colleagues examined the prevalence of prediabetes by presence or absence of advers

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

A novel male contraceptive gel suppresses sperm production faster than other hormone-based methods for male birth control, according to a phase 2 study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Danielle Gross, from the Eunice Kennedy Shriver National Institute of Child Health and Human Developme

Most patients with thyroid eye disease treated with teprotumumab do not require additional treatments nearly two years later, according to a study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston, and simultaneously published online June 2 in&nbsp;Thyroid.George J. Kahaly, M.D., Ph.D., from the

Women with early menopause have a two times greater risk for breast cancer and a nearly four times higher risk for ovarian cancer, according to a study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Kristina&nbsp;L. Allen-Brady, Ph.D., M.P.H., from University of Utah in Salt Lake City, and colleagues i

For adults with advanced, insulin-treated type 2 diabetes (T2D), willingness to participate in an intensive lifestyle intervention (ILI) is very low, according to a research letter published online June 5 in Diabetes, Obesity and Metabolism.Cathy J. Sun, M.D., from The Ottawa Hospital in Ontario, Canada, and colleagues designed an ILI p

Bariatric metabolic surgery (BMS) is associated with a greater reduction in mortality than glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment among adults with a diabetes duration of 10 years or less, according to a study published online June 7 in JAMA Network Open.Dror Dicker, M.D., from Rabin Medical Center in Petah Tikva,

Empiric vitamin D supplementation is suggested for those aged 1 to 18 years, those older than 75 years, those who are pregnant, and those with high-risk prediabetes, according to an Endocrine Society clinical practice guideline published online June 3 in the Journal of Clinical Endocrinology &amp; Metabolism.Marie B. Demay, M.D., from M

For adults with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), glucagon-like peptide 1 receptor agonists (GLP-1 RA) and sodium-glucose cotransporter 2 inhibitors (SGLT-2i) are associated with reduced risk of cardiovascular (CV) events compared with dipeptidyl peptidase 4 inhibitors (DPP-4i), according to a st

Isotretinoin is well tolerated and effective for individuals receiving masculinizing gender-affirming hormonal therapy who have acne, according to a study published online May 29 in JAMA Dermatology.James Choe, from Brigham and Women's Hospital in Boston, and colleagues examined clinical outcomes of isotretinoin among transgender and gen

For glucose and lipid profiles during early childhood, the impact of frozen embryo transfer (FET) is comparable to that of fresh embryo transfer, according to a study published online June 6 in PLOS Medicine.Wei Zhou, from Shandong University in Jinan, China, and colleagues compared the metabolic profiles of children born after frozen ve

Popular smoking cessation aids are equally effective in those with or without a history of mental health conditions, according to a study published online June 4 in&nbsp;PLOS Mental Health.Sarah E. Jackson, Ph.D., from University College London, and colleagues examined whether the real-world effectiveness of popular smoking cessation a

Crinecerfont results in a greater decrease from baseline in the mean daily glucocorticoid dose among patients with congenital adrenal hyperplasia (CAH), according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Richa

Excess mortality persisted in 2020 through 2022 in the Western world, according to a study published online June 3 in BMJ Public Health.Saskia Mostert, M.D., from Amsterdam UMC, and colleagues explored excess mortality in the Western world from 2020 to 2022 using all-cause mortality reports abstracted from the "Our World in Data" databa

Markers of diabetes are positively associated with overactive bladder (OAB), according to a study published online April 28 in&nbsp;Frontiers in Endocrinology.Qingliu He, from Jinjiang Municipal Hospital in Quanzhou, China, and colleagues used data from six cycles of the U.S. National Health and Nutrition Examination Survey (23,863 part

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

For individuals with mixed hyperlipidemia, plozasiran reduces triglyceride levels at 24 weeks, according to a study published online May 28 in the New England Journal of Medicine.Christie M. Ballantyne, M.D., from the Baylor College of Medicine and Texas Heart Institute in Houston, and colleagues conducted a 48-week, randomized trial ass

The optimal body mass index (BMI) cutoff point appears to be 27 kg/m2 for detecting obesity in middle-aged and older adults, according to a study presented at the annual meeting of the European Congress on Obesity, hosted by the European Association for the Study of Obesity from May 12 to 15 in Venice, Italy.Marwan El Ghoch, M.D., from

For patients with type 2 diabetes and chronic kidney disease, semaglutide reduces the risk for clinically important kidney outcomes and death from cardiovascular causes, according to a study published online May 24 in the New England Journal of Medicine to coincide with the annual European Renal Association Congress, held from May 23 to 26 in S

A primary care-based weight navigation program (WNP) is feasible and associated with greater use of weight management treatments (WMT) and weight loss, according to a study published online May 21 in JAMA Network Open.Dina H. Griauzde, M.D., from the University of Michigan Medical School in Ann Arbor, and colleagues examined the associat

The individualized metabolic surgery score could help set realistic weight loss targets with semaglutide in patients with type 2 diabetes and obesity.

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

Specific demographic, clinical, and financial characteristics are associated with glucagon-like peptide 1 (GLP-1) receptor agonist discontinuation, according to a research letter published online May 24 in&nbsp;JAMA Network Open.Duy Do, Ph.D., from the Evernorth Research Institute in St. Louis, and colleagues estimated the prevalence

Patients with T2D who were sedentary for less than 6 hours a day had reduced mortality risk, and moderate physical activity enhanced longevity in those with more sedentary habits.

Combination therapy of bupropion/naltrexone and GLP-1 receptor agonists showed a synergistic weight loss effect in individuals with obesity who responded poorly to GLP-1 monotherapy.

At a recent diabetes conference, experts debated the relative merits of exercise and medication for weight loss in this patient population.

As millions seek access to weight-loss drugs from Novo Nordisk and Eli Lilly, increasing supplies, possible wider usage and a growing number of would-be rivals are leading...

Glycemic patterns detected by continuous glucose monitoring (CGM) may help diagnose gestational diabetes earlier in pregnancy, which may help improve perinatal outcomes.

A majority of the advisory committee voted that the benefits of insulin icodec don't outweigh the increased risk of hypoglycemia in type 1 diabetes.

Prenatal exposure to endocrine-disrupting chemicals (EDCs) is associated with adverse metabolic health in children, according to a study published online May 23 in JAMA Network Open.Nuria Güil-Oumrait, from the Barcelona Institute for Global Health in Spain, and colleagues examined associations of prenatal exposure to EDC mixtures with t

Agents in development would preserve lean body mass and further promote fat loss in people taking new antiobesity medications for weight loss.

Women who take hormone therapy showed a better response to GLP-1 drugs and lost more weight.

CPAs are the result of gene mutations leading to the development of two-layer nodules that have tumor-inducing and suppressing effects, suggested a new study.

For adolescents and young adults, glucagon-like peptide-1 receptor agonist (GLP-1 RA) dispensing increased from 2020 to 2023, according to a research letter published online May 22 in the Journal of the American Medical Association.Joyce M. Lee, M.D., M.P.H., from the University of Michigan Medical School in Ann Arbor, and colleagues

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

Early serum cortisol > 237 nmol/L validated as a screen for predicting the recovery of the HPA axis in patients on tapering regimes from long‐term chronic glucocorticoid therapy.

A single-center chart review found that postmenopausal women with osteoporosis may be started on antiresorptive therapy without having had secondary causes ruled out.

Text messages with financial incentives for men with obesity led to nearly two thirds losing 5% body weight over a year, and many men were from socially deprived groups.

A short semaglutide video on TikTok drew close to 1 million views.

In older adults with T1D, less daytime hypoglycemia was the biggest predictor of improvements in IAH in a 6-month study.

Nestle will market a new, $5 line of frozen pizzas and protein-enriched pastas in the United States which it says it designed specifically for people taking drugs such as...

Both financial and physical food insecurity increased the risk, but standard questions didn't capture the latter.

Fezolinetant is safe and effective for moderate-to-severe vasomotor symptoms (VMS), according to a study presented at the annual European Congress of Endocrinology, hosted by the European Society of Endocrinology from May 11 to 14&nbsp;in Stockholm.Angelica Lindén Hirschberg, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleague

Arm fat may predict risk for spinal fracture, according to a study presented at the annual European Congress of Endocrinology, hosted by the European Society of Endocrinology from May 11 to 14&nbsp;in Stockholm.Maria Eleni Chondrogianni, from the National and Kapodistrian University of Athens in Greece, and colleagues investigated the association

In a clinical guideline issued jointly by the European Society of Endocrinology and the Endocrine Society, recommendations are presented for the diagnosis and management of glucocorticoid-induced adrenal insufficiency. The guideline was published online May 8 simultaneously in the European Journal of Endocrinology and the Journal of Clinica

Glucose above the diagnostic threshold at the time of gestational diabetes diagnosis is associated with worse neonatal outcomes, according to a study presented at the annual European Congress of Endocrinology, hosted by the European Society of Endocrinology from May 11 to 14&nbsp;in Stockholm.Catarina Cidade-Rodrigues, M.D., from Centro Hospitala

People whose body mass index (BMI) slightly increases from normal weight to low-level overweight during 30 years of middle adulthood have a lower risk for fracture in later life, according to a study published online April 8 in&nbsp;Osteoporosis International.Zihao Xin, from the Boston University School of Public Health, and colleagues e

Men with diabetes have a greater risk for complications than women, irrespective of diabetes duration, according to a study published online May 16 in the&nbsp;Journal of Epidemiology &amp; Community Health.Alice A. Gibson, from the University of Sydney, and colleagues investigated sex differences in incident microvascular and macrovascu

In comparing women and men with obesity, researchers proposed that the latter are more insulin resistant due to less efficient inhibition of fat cell lipolysis.

An AID system improved glycemic outcomes in adults with long-standing T1D who struggled to meet their glycemic targets using insulin pumps and CGM.

Research into micro-, nano-, and macroencapsulation has led to historic moments, according to an expert endocrinologist.

Food emulsifiers, a common ingredient in many ultraprocessed foods consumed by millions worldwide, increased the risk for incident type 2 diabetes.

Weight loss is similar for individuals using a wireless feedback system (WFS) that provides daily information on lifestyle change and weight loss versus the same system augmented with human coaching, according to a study published online May 14 in the&nbsp;Journal of the American Medical Association. The research was published to coincide wit

The conventional BMI cutoff for obesity may be better replaced with adiposity measures that accommodate changes in the body fat-to-muscle ratio that changes in the midlife years.

A KFF poll also suggests half of the respondents who had tried these weight loss meds no longer took them, with many reporting difficulties paying for these drugs.

Best management practice for glucocorticoid-induced adrenal insufficiency has been developed jointly by endocrinologists in Europe and the United States.

Phase 3 data for efsitora alfa showed noninferiority to once-daily basal insulins in two studies of people with type 2 diabetes.

In the 2019 to 2020 school year, 20.9 percent of New York City elementary and middle school students had obesity, and 6.4 percent had severe obesity, according to a study published online May 15 in&nbsp;PLOS ONE.Kira L. Argenio, M.P.H., from the New York City Department of Health and Mental Hygiene, and colleagues estimated the preval

Among men with obesity, an intervention with text messaging plus financial incentive significantly improves weight loss compared with a control group, according to a study published online May 14 in the&nbsp;Journal of the American Medical Association&nbsp;to coincide with the annual meeting of the European Congress on Obesity, hosted by the

Use of an artificial intelligence (AI)-informed health app aids diabetes outcomes and cuts atherosclerotic cardiovascular disease (ASCVD) risk, according to a study presented at the annual meeting of the American Association of Clinical Endocrinology, held from May 9 to 11 in New Orleans.Paramesh Shamanna, M.D., from the Bangalore Diabetes Cent

Individuals taking glucagon-like peptide (GLP)-1 receptor agonists have a greater risk for subsequently being dispensed antidepressants, according to a study published online April 23 in&nbsp;Diabetes, Obesity, and Metabolism.Osvaldo P. Almeida, Ph.D., from University of Notre Dame in Fremantle, Australia, and colleagues assessed whet

Switching from one healthy weight loss diet to another did not overcome the typical weight loss plateau at 6 months in individuals with overweight and obesity.

The loss of lean mass has become a hot topic with new anti-obesity drugs, but such changes can occur with most successful weight loss interventions — without meaningful countermeasures.

Treatment with setmelanotide, a melanocortin-4 receptor agonist, led to a significant reduction in BMI in a difficult-to-treat population of patients with hypothalamic obesity.

Novo Nordisk does not expect a shortage of its Wegovy weight-loss drug in Denmark despite an earlier warning by the Danish Medicines Agency of strained supply of two...

One in eight adults (12 percent) say they have ever taken a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and 6 percent say they are currently using one, according to the results of a new KFF Health Tracking Poll, released May 10.Alex Montero, from KFF Health, and colleagues analyzed data collected April 23 to May 1, 2024, online and by te

Eli Lilly has entered into a settlement deal with a medi spa that had sold counterfeit versions of its popular diabetes drug Mounjaro and weight loss treatment Zepbound, the...

Among slow responders to tirzepatide treatment at week 12, 90 percent went on to achieve clinically meaningful weight reduction (≥5 percent) by week 72, according to a study presented at the annual meeting of the American Association of Clinical Endocrinology, held from May 9 to 11 in New Orleans.Kimberly Gudzune, M.D., from Johns Hopkins Univer

Semaglutide remains effective for weight loss at 4 years in people with preexisting cardiovascular disease and overweight/obesity but without T2D and provides CV benefits regardless of weight.

A digital lifestyle program used in combination with semaglutide from low starting dose shows participants can maintain weight loss after tapering and stopping the drug, irrespective of starting BMI.

Small study finds that adrenalectomy improves bone quality but not density in MACS, suggesting that the former is key to the increased fracture risk in the condition.

Self-perceived weight as a child may influence risks for all-cause mortality and incident cardiovascular disease in adults who are overweight or obese.

Already approved for treating achondroplasia, the drug also appears to accelerate growth in children with other genetic growth-limiting conditions.

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

Exposure to branded products on live-streaming video game platforms may drive excess eating and weight gain.

Inadequate current treatment of congenital adrenal hyperplasia using glucocorticoids suggested potential benefit of investigational drug.

Cardiovascular, kidney, and metabolic (CKM) syndrome is highly prevalent in the United States, with more than 90 percent of adults meeting the criteria for stage 1 or higher, according to a research letter published online May 8 in the Journal of the American Medical Association.Rahul Aggarwal, M.D., from Harvard Medical School in Boston

Treatment guidelines that advise stopping a weight-loss drug if weight loss isn't achieved by 12 weeks don't account for the titration required, investigator says.

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

Findings refute those of a prior study suggesting a better response in older vs younger patients.

Data suggest a lack of compliance with assessments to prevent ophthalmologic and neuropathic complications of diabetes in several countries.

Even low levels of arsenic in drinking water, below the current regulatory limits, increased the risk for incident T2D in racially and ethnically diverse urban US communities.

The new anti-obesity drugs could be as beneficial for the treatment of adolescents as adults — but obstacles may require creative strategies.

For individuals with limited English proficiency, there are disparities in telehealth access, as well as worse video visit experiences, according to a research letter published May 9 in&nbsp;JAMA Network Open.Jorge A. Rodriguez, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from 24,453 adult participants in

Gestational diabetes is associated with an increased risk for subsequent diabetes, with higher risk for gestational diabetes in second pregnancy and in both first and second pregnancies, according to a study published online May 9 in JAMA Network Open.Joseph Mussa, from McGill University in Montreal, and colleagues compared the hazards

The U.S. Food and Drug Administration has issued a Class 1 recall -- its most urgent kind -- for an IOS app linked to a specific kind of insulin pump used by people with diabetes.The <a href="https://www.fda.gov/medical-devices/medical-device-recalls/tandem-diabetes

Mortality is slightly higher in association with a higher intake of ultraprocessed foods, according to a study published online May 8 in The BMJ.Zhe Fang, M.B.B.S., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues conducted a population-based cohort study to examine the association of ultraprocessed food cons

Distal symmetric polyneuropathy (DSP) is common and is frequently undiagnosed, according to a study published online May 8 in Neurology.Melissa A. Elafros, M.D., Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined whether data accurately reflect the prevalence, risk factors, and burden of DSP in the population.

The recall warns of a software glitch with the t:connect mobile app that can lead to battery failure of the t:slim X2 insulin pump.

A new review paper summarized what is and isn't known.

Health and wellness products retailer Vitamin Shoppe said on Wednesday that subscribers to its telehealth service would have access to weight-loss medications such as...

Low free T4 is common, but the incidence of central hypothyroidism is rare.

At a recent conference, experts reviewed the data about pharmaceutical treatments, topical medicines, and neuromodulation for this indication.

Combining time-restricted eating (TRE) with high-intensity functional training (HIFT) may have superior effects on body composition, lipid profile, and glucose regulation among inactive women with obesity compared with diet or exercise interventions alone, according to a study published online May 1 in PLOS ONE.Ranya Ameur, from Universi

The off-label use of CGMs for people possibly on the verge of, but not yet diagnosed with, diabetes is seen as a potential tool to help reverse course; over-the-counter version highly anticipated.

The time to weight loss plateau is longer with both GLP-1 receptor agonists and bariatric surgery than with diets alone due to their effect on appetite, not energy expenditure.

Exposure to food additive emulsifiers is associated with an increased risk for type 2 diabetes, according to a study published in the May issue of The Lancet Diabetes &amp; Endocrinology.Clara Salame, Ph.D., from the Université Sorbonne Paris Nord and Université Paris Cité, and colleagues analyzed data from 104,139 adults enrolled in the

New data find gastric contents after fasting aren't higher than nondiabetics, but an expert endocrinologist disputes that conclusion and GLP-1 agonists further complicate the picture.

Compared with standard antihypertensive therapy, intensive antihypertensive therapy may significantly benefit women with T2D whose hypertension is diagnosed earlier in life.

From 1990 to 2021, there were persistent health differences between females and males, according to a study published online May 1 in The Lancet Public Health.Vedavati Patwardhan, Ph.D., from the University of California, San Diego, and colleagues compared disability-adjusted life year (DALY) rates among females and males aged older than

Older adults with diabetes are more likely to develop functional limitations than adults without diabetes, according to a study published online April 16 in the Canadian Journal of Diabetes.Andie MacNeil, from the Institute for Life Course and Aging at the University of Toronto, and colleagues compared changes in functional limitations du

FRIDAY, May 3, 2024 (HealthDay News) --&nbsp;Adherence to physical activity guidelines during middle age appears to improve health-related quality of life among women, according to a study published online May 2 in PLOS Medicine.Binh Nguyen, Ph.D., of the University of Sydney, and colleagues evaluated data from 11,336 participants in the Australian Longitudinal Study on Women's

The idea that sensory neuropathy affects small fibers and that painful neuropathy affects large fibers must be reconsidered, said a diabetologist.

A once-daily injectable therapy of a fixed-ratio combination of insulin glargine and lixisenatide improved glycemic control, with low rates of hypoglycemia, in people with T2D in a real-world setting.

As the treatment of obesity in the 21st century takes a monumental turn, the need for quality care is more pressing than ever: Tips for starting a new obesity-focused practice.

Use of sodium–glucose cotransporter-2 inhibitors (SGLT2is) is associated with a substantially lower risk for dialysis and cardiovascular disease in patients with type 2 diabetes (T2D) and stage 5 chronic kidney disease (CKD), according to a study published online April 30 in the Annals of Internal Medicine.Fu-Shun Yen, M.D., from Dr. Ye

THURSDAY, May 2, 2024 (HealthDay News) — The U.S. Environmental Protection Agency (EPA) said it will spend $3 billion to help states and territories identify and replace lead water pipes."The science is clear, there is no safe level of lead exposure, and the primary source of harmful exposure in drinking water is through lead pipes," EPA Administrator <a href="https://www.epa.gov/aboute

High doses of PUFAs didn't differentially affect lean tissue accumulation in middle-aged individuals with overweight, as in the elderly and young lean populations.

Study finds slightly higher risk in children at 10 years, but experts say this shouldn't change current supplementation recommendations.

Adherence to healthy lifestyles can largely overcome the genetic risk for a shorter lifespan, according to a study published online April 29 in BMJ Evidence Based Medicine.Zilong Bian, from the Zhejiang University&nbsp;School of Medicine in&nbsp;Hangzhou, China, and colleagues investigated associations of genetic and lifestyle factors

A new term is intended to limit negative connotations, but some experts consider it imprecise and difficult to interpret.

The US Food and Drug Administration grants new status to Sensionics' Eversense

Following a medically supervised energy-restricted diet 2 days a week could improve glycemic control in patients with overweight or mild obesity and type 2 diabetes.

A study in a primarily Hispanic population points to the need for improved communication between patients and providers.

Denmark will start putting patients suffering from type 2 diabetes on cheaper drugs before prescribing so-called GLP-1 drugs such as Novo Nordisk's Ozempic, the Danish...

For people with HIV (PWH), semaglutide is effective for metabolic dysfunction-associated steatotic liver disease (MASLD), according to a research letter published online April 30 in the Annals of Internal Medicine.Jordan E. Lake, M.D., from UTHealth Houston, and colleagues designed a pilot study to examine the effect of semaglutide on

People with opioid use disorder (OUD) are less likely to receive palliative care during the last 90 days before death, according to a study published online April 29 in CMAJ, the journal of the Canadian Medical Association.Jenny Lau, M.D., from the University Health Network in Toronto, and colleagues conducted a cohort study using heal

More intensive hypertensive therapy significantly reduces the excess risk for cardiovascular disease (CVD) events associated with earlier hypertension diagnosis in women, but not men, with type 2 diabetes, according to a study published online April 24 in Diabetes Care.Hongwei Ji, M.B.B.S., Ph.D., from Tsinghua University in Beijing, a

For patients with metastatic pheochromocytomas and paragangliomas (MPPGs), an antiangiogenic multi-tyrosine kinase inhibitor, cabozantinib, is promising, according to a study published online April 9 in The Lancet Oncology.Camilo Jimenez, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted

A long-awaited ban on menthol cigarettes has been delayed indefinitely, the Biden administration said Friday.“This rule has garnered historic attention, and the public comment period has yielded an immense amount of feedback, including from various elements of the civil rights and criminal justice movement,” U.S. Health and Human Service Secret

For patients with advanced adrenocortical carcinoma, cabozantinib shows promising efficacy, according to a study published online April 9 in The Lancet Oncology.Matthew T. Campbell, M.D., from The University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted a single-arm, phase 2 trial in adults with advanced adren

Sarcopenic obesity, which is characterized by excess adiposity and muscle loss, is an underestimated and underdiagnosed condition, experts say.

The risk for postoperative respiratory complications is similar among patients undergoing emergency surgery regardless of preoperative glucagon-like peptide 1 receptor agonist (GLP-1 RA) use, according to a research letter published online April 22 in the&nbsp;Journal of the American Medical Association.Anjali A. Dixit, M.D., M.P.H.,

School lunches will soon contain less added sugar and salt under new nutrition standards announced by the U.S. Department of Agriculture on Wednesday.“We all share the goal of helping children reach their full potential,” Agriculture Secretary Tom Vilsack said in a news release ann

Researchers demonstrated the model's excellent performance, raising hopes that it can someday prove a valuable tool for reducing such events in hospitalized patients.

The timing of moderate to vigorous physical activity was associated with a lower risk for mortality and CVD in adults with obesity, including those with type 2 diabetes.

Glucagon-like peptide 1 (GLP1) receptor agonist use does not appear to be associated with an increased risk for thyroid cancer, according to a study published online April 10 in The BMJ.Björn Pasternak, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined whether use of a GLP1 receptor agonist is associa

Northeastern U.S. seafood consumers may be exposed to per- and polyfluoroalkyl substance (PFAS) concentrations that potentially pose a health risk, according to a study published online April 12 in Exposure and Health.Kathryn A. Crawford, Ph.D., from the Environmental Studies Program at Middlebury College in Vermont, and colleagues

A U.S. Senate committee said on Wednesday it had launched an investigation into the prices of Novo Nordisk's diabetes and weight loss drugs Ozempic and Wegovy in the United...

A budget-busting 3.6 million Medicare recipients could now be eligible for coverage of the weight-loss drug Wegovy, a new KFF analysis says.That’s because the U.S. Food and Drug Administration has approved the use of Wegovy (semaglutide) to reduce the risk of <a href="https://www.healthday.com/a-to-z-health/cardiovascular-diseases/heart-atta

An endocrinologist reviewed a crucial chapter in the latest position statement by the Francophone Diabetes Society at a recent conference.

About 3.6 million overweight or obese patients with heart conditions insured under the U.S. Medicare program could be eligible for coverage of Novo Nordisk's weight-loss...

Time-restricted eating (TRE) is not associated with weight loss or glycemic improvements compared with a usual eating pattern (UEP) when calories are held constant in both groups, according to a study published online April 19 in the&nbsp;Annals of Internal Medicine to coincide with presentation at the Internal Medicine Meeting, the annual m

Young men appeared particularly vulnerable.

Compared with healthy individuals, Asian patients with prediabetes had relatively less abundance of gut bacteria associated with normal physiological functions and metabolism.

In a clinical guideline issued by the American College of Physicians (ACP) and published online April 19 in the Annals of Internal Medicine, recommendations are presented regarding newer pharmacologic treatments for adults with type 2 diabetes. Details of the guideline were also presented at the Internal Medicine Meeting, the

Two common PFAS "forever chemicals" have been deemed hazardous substances by the Environmental Protection Agency.The new designation, enacted under the country's <a href="https://www.epa.gov/laws-regulations/summary-comprehensive-environmental-response-compensation-and-liability-act#:~:text=The%20Comprehensive%20Environmental%20Response%2C%20Co

For individuals with moderate-to-severe chronic kidney disease (CKD), a model, KDpredict, can accurately predict the risk for kidney failure and death, according to a study published online April 15 in The BMJ.Ping Liu, Ph.D., from the University of Calgary in Alberta, Canada, and colleagues conducted a population-based cohort study in

Growth hormone deficiency appears to be linked to a particular microbiome signature that could help with the early diagnosis and treatment of short stature, suggest study.

Data on the investigative, temporary gut liner, EndoBarrier, showed improvement in weight, A1c, fatty liver, and need for insulin, and the effect persisted for up to 2 years after its removal.

Nearly one-fifth of fresh, frozen, and canned fruits and vegetables that Americans eat contain concerning levels of pesticides, posing significant risks from produce such as strawberries, green beans, bell peppers, blueberries, and potatoes, according to a review published by Consumer Reports."One food in particular, green beans, had

Deep-seated racial and ethnic disparities persist in health care across the United States, even in states considered the most progressive, a new report shows.For example, California received a score of 45 for the care its health system provides Hispanic Americans. The Commonwealth Fund report gives each state a 0-to-100 score for each populat

A wealth of data shows that endocrine-disrupting compounds are a constant, multifaceted, and pervasive health risk.

Antidepressant use may be a marker for more severe and unsuccessfully treated depression.

Researchers have figured a way to use a smartphone's magnetometer to measure sugar and pH levels.

Sleeping for more than 7 hours at night may improve cardiometabolic health in patients with type 1 diabetes, especially teenagers, showed an analysis.

Eli Lilly said on Wednesday its weight-loss drug helped reduce episodes of irregular breathing associated with a common sleep-related disorder in two late-stage trials,...

Working-age adults in the United States are dying at higher rates than their peers in high-income countries, according to a study published online March 21 in the&nbsp;International Journal of Epidemiology.Jennifer Beam Dowd, Ph.D., from the University of Oxford in the United Kingdom, and colleagues synthesized cause-specific mortalit

New data showed considerable intrapersonal variability in fasting glucose and suggested that CGM adds important information.

DFUs strike 1.6 million a year in the United States; half develop infections, which can lead to amputation and death. New treatments, new drug trial guidance, and team approach to care may help.

Replacing sugar with sweeteners didn't increase appetite and lowered blood glucose levels in adults with overweight and obesity, showed a randomized trial.

From 2011 to 2020, there was an increase in total annual prescription medication expenditures, with antimetabolic agents the most costly category, according to a study published in the April issue of Research in Social and Administrative Pharmacy.Whanhui Chi, from the University of Houston College of Pharmacy, and colleagues calculated

Americans are facing more shortages of the drugs they need for medical care than ever before, a national pharmacy database shows.The American Society of Health-System Pharmacists (ASHSP) and the University of Utah Drug Information Service started tracking drug shortages as far back as 2001. Their latest <a href="https://www.ashp.org/drug

Researchers compared the effects of a low-fat vegan diet with those of a conventional portion-control diet in individuals with type 1 diabetes in a randomized clinical trial.

The cybersecurity firm BrandShield has taken down more than 250 websites selling fake versions of popular weight-loss and diabetes drugs in the GLP-1 class, the company’s...

Evidence is lacking for use of puberty blockers and hormone treatment for gender dysphoria/incongruence, according to two systematic reviews published online April 10 in the Archives of Disease in Childhood.Jo Taylor, Ph.D., from the University of York in the United Kingdom, and colleagues conducted a systematic review and meta-analysi

For patients with multifocal papillary thyroid carcinoma (PTC), the rates of progression-free survival (PFS) do not differ between microwave ablation (MWA) and surgical resection (SR), according to a study published online April 2 in Radiology.Zhen-Long Zhao, M.D., from the China-Japan Friendship Hospital in Beijing, and colleagues com

Among people with hypothyroidism, the prevalence of type D personality (a vulnerability factor for general psychological distress) is high, according to a study published online April 9 in the Journal of Clinical Endocrinology &amp; Metabolism.Petros Perros, M.B.B.S., M.D., from Newcastle University in the United Kingdom, and colleague

Semaglutide is an effective treatment option for weight loss, but its cost-effectiveness over the long term compared with ESG needs to be considered.

Insights into factors affecting postexercise glucose fluctuations in adolescents with T1D could shape new guidelines and decision support tools.