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All articles tagged: Diabetes & Endocrinology

MedScape 20 November at 10.53 PM

Ultraprocessed Foods Linked to Faster Biological Aging

Higher consumption of ultraprocessed foods, such as carbonated drinks, processed meats, and sweet or savory packaged snacks, is associated with accelerated biological aging.

HealthDay 20 November at 04.04 PM

AHA: Intensive Strategy for Lowering Systolic BP Beneficial in Type 2 Diabetes

For patients with type 2 diabetes and elevated systolic blood pressure, an intensive-treatment strategy is better than a standard-treatment strategy for incidence of major cardiovascular disease events, according to a study published online Nov. 16 in the New England Journal of Medicine to coincide with the American Heart Association Scient

HealthDay 20 November at 11.06 AM

Four Million Americans Could Lose Health Coverage Once ACA Credits Expire

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

HealthDay 20 November at 11.04 AM

Surgeon General Says U.S. Smoking Rates Have Tumbled, But Not for Everyone

Although the United States has made significant headway in curbing cigarette smoking and secondhand smoke exposure, a new report finds deep divisions remain and they run along predictable fault lines.Disparities in tobacco use continue to persist by income and occupation, geography, education, race and ethnicity, sexual orientation and gender

MedScape 20 November at 06.15 AM

Weight-loss Drug Coverage Rises Among Largest US Employers, Mercer Survey Finds

About 44% of U.S. employers with 500 or more employees cover drugs for weight loss in 2024, up from 41% in 2023, according to a survey from consulting firm Mercer released...

HealthDay 19 November at 11.50 PM

President-Elect Trump to Pick Mehmet Oz to Head CMS

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

MedScape 19 November at 09.00 AM

What Are the Priorities of People With Type 1 Diabetes?

Newer themes prioritised among "top 10" included the use of artificial intelligence, provision of holistic care, access to newer therapies, and women's health.

MedScape 19 November at 08.06 AM

Does Light-Intensity Walking Benefit Blood Glucose?

Light-intensity walking reduced postprandial glucose and diastolic blood pressure in young adults with obesity.

MedScape 19 November at 06.51 AM

Can Plant-Based Diet Deliver Ample Protein for Older Adults?

Diets with more plant-based protein are likely to be safe for adults aged over 65, except for a vegan scenario that failed to provide enough protein in most people, a simulation study found.

MedScape 19 November at 06.17 AM

Telehealth Vs In-Person Diabetes Care: Is One Better?

Close to half of US adults with diabetes used telehealth services in 2022 and generally reported care comparable with that of in-patient visits.

HealthDay 18 November at 10.38 PM

Metformin Use Tied to Lower Rate of Asthma Attacks

Metformin is associated with a lower rate of asthma attacks among people with diabetes, according to a study published online Nov. 18 in JAMA Internal Medicine.Bohee Lee, Ph.D., from Imperial College London, and colleagues estimated the association of metformin and add-on antidiabetic medications (glucagon-like peptide-1 receptor a

HealthDay 18 November at 04.32 PM

AHA: AI Analysis of Images, Videos Can ID Early Hypertension, Diabetes

Machine learning analysis of photo and video data demonstrates a promising way to noninvasively detect early hypertension and diabetes, according to a study presented at the American Heart Association Scientific Sessions 2024, held from Nov. 16 to 18 in Chicago. Ryoko Uchida, from University of Tokyo, and colleagues developed a machine learning

HealthDay 18 November at 04.21 PM

Tirzepatide Yields Sustained Weight Reduction in Obesity, Prediabetes

For patients with obesity and prediabetes, three years of tirzepatide yields substantial and sustained weight reduction and a reduced risk for progression to type 2 diabetes, according to a study published online Nov. 13 in the New England Journal of Medicine.Ania M. Jastreboff, M.D., Ph.D., from the Yale School of Medicine in New Haven

MedScape 18 November at 08.06 AM

Adjusting Thyroid Ranges for Age Cuts Hypothyroidism Rates

‘Normal’ TSH and FT4 concentrations change with age, and the failure to consider those changes in assessment can lead to misdiagnosis and overtreatment.

MedScape 18 November at 06.42 AM

Vitamin D May Lower Blood Pressure in Overweight Seniors

Vitamin D supplementation decreased blood pressure in older individuals with overweight, according to a post hoc analysis of a randomized controlled trial.

MedScape 18 November at 06.02 AM

Exclusive-Medicaid Fuels US Coverage Of Novo, Lilly Weight-loss Drugs

U.S. government health plans account for the lion's share of coverage for popular new weight-loss drugs, far beyond the reimbursement available from private employers and...

HealthDay 15 November at 11.09 PM

Higher Physical Activity Levels Can Increase Life Expectancy

Higher physical activity (PA) levels can increase life expectancy, according to a study published online Nov. 14 in the British Journal of Sports Medicine.Lennert Veerman, M.D., M.P.H., Ph.D., from the Griffith University School of Medicine and Dentistry in Gold Coast, Australia, and colleagues estimated how much low PA reduces life exp

HealthDay 15 November at 10.38 PM

Risk for Mortality Up With Low Income in Type 2 Diabetes

Adults with type 2 diabetes (T2D) have an increased risk for mortality in association with low income, with the most prominent increase seen for adults aged 20 to 39 years, according to a study published online Nov. 12 in JAMA Network Open.Ji Yoon Kim, M.D., Ph.D., from the Korea University College of Medicine in Seoul, and colleagues e

HealthDay 15 November at 04.47 PM

Burden of Diabetes, Untreated Diabetes Increased From 1990 to 2022

The global burden of diabetes and untreated diabetes increased from 1990 to 2022, according to a study published online Nov. 13 in The Lancet.Bin Zhou, Ph.D., from Imperial College London, and colleagues used data from 1,108 population-representative studies with 141 million participants aged 18 years and older to examine trends in diab

MedScape 15 November at 07.20 AM

More Than 800 Million People Worldwide Have Diabetes

Increasingly, the burden falls on low- and middle-income countries.

MedScape 15 November at 05.45 AM

Managing Diabetes and Dementia in Long-Term Care

Deprescription and the prevention of hospitalization should be priorities, rather than aggressive management, a family physician advised.

HealthDay 14 November at 11.47 PM

President-Elect Trump Nominates Robert F. Kennedy Jr. to Lead HHS

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

MedScape 14 November at 06.30 PM

Obesity in the US Projected to Skyrocket by 2050

If current trends continue, more than 250 million Americans will have overweight or obesity in the next quarter-century.

HealthDay 14 November at 04.40 PM

ASH: GLP-1 RA Use Tied to Lower Rate of Venous Thromboembolism in Diabetes

For patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a lower risk for venous thromboembolism (VTE), according to a study scheduled for presentation at the annual meeting of the American Society of Hematology, to be held from Dec. 9 to 12 in San Diego.Cho Han Chiang, M.D.,

HealthDay 14 November at 04.29 PM

Incidence of Dyslipidemia Elevated During COVID-19 Pandemic

There was an increase in dyslipidemia incidence during the COVID-19 pandemic compared with the prepandemic period, according to a study published online Sept. 12 in the Journal of Clinical Investigation.Valentina Trimarco, from Federico II University in Naples, Italy, and colleagues conducted a six-year longitudinal study to examine t

HealthDay 14 November at 04.22 PM

Fasting at Night May Aid Glucose Metabolism in Night-Shift Workers

Fasting at night prevents impairments in glucose tolerance among simulated night-shift work, according to a study published online Oct. 18 in Diabetologia.Stephanie Centofanti, Ph.D., from University of South Australia in Adelaide, and colleagues assigned healthy, non-shift-working adults without obesity to fasting-at-night (20 indivi

MedScape 14 November at 06.43 AM

Novo Nordisk Says It Is Gradually Phasing Out Human Insulin Pens Globally

Novo Nordisk is gradually ending production of human insulin pens, the drugmaker told Reuters, as it spends billions to ramp up manufacturing of its popular obesity and...

MedScape 14 November at 06.02 AM

GLP-1 Prescribing Decisions: Compounded or Brand-Name?

With brand-name GLP-1s for obesity treatment on and off the shortage list, prescribing can get complicated. Five providers told us how they cope.

MedScape 14 November at 03.22 AM

Managing Long-Term Health Risks in Thyroid Cancer Survivors

ATA 2024 spotlighted new research to help endocrinologists manage the subsequent fertility, bone health, and cardiovascular disease risks of thyroid cancer survivors.

MedScape 14 November at 03.03 AM

Semaglutide 2.4 mg Could Cut Medical Costs for Some

A manufacturer-funded study found a significant decrease in annual total medical costs in patients with overweight/obesity and heart failure.

HealthDay 13 November at 04.39 PM

Even Adding a Few Extra Minutes of Exercise Daily Lowers Blood Pressure

Small additional amounts of exercise each day are associated with lower blood pressure (BP) in a free-living setting, according to a study published online Nov. 6 in Circulation.Joanna M. Blodgett, Ph.D., from University College London, and colleagues investigated associations between a 24-hour behavior composition composed of s

MedScape 13 November at 07.06 AM

Weight Loss Treatments Beyond the Reach of Many in Need

New findings demonstrated people with obesity rationing medications, a lack of Medicaid coverage in many US states, and the emotional aftermath of coverage loss.

MedScape 13 November at 05.24 AM

Amgen Dismisses Bone Density Concerns Related to Its Weight-loss Drug

Amgen said on Wednesday there was no link between its experimental weight-loss drug and changes in bone density, a day after those concerns wiped off more than $12 billion...

HealthDay 12 November at 04.17 PM

Vigorous Activity Can Compensate for Prolonged Sitting Time

An age-equivalent benefit is found for vigorous exercise, after considering sitting time, according to a study recently published in PLOS ONE.Ryan Bruellman, from the University of California Riverside, and colleagues analyzed data from the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging in adults ag

MedScape 12 November at 06.23 AM

Continuous Glucose Monitors for All? Opinions Remain Mixed

The question is more urgent as over-the-counter continuous glucose monitoring devices become more widely available.

MedScape 12 November at 04.56 AM

Sustained Benefits With TransCon PTH in Hypoparathyroidism

Adults with hypoparathyroidism treated with TransCon PTH in the phase 3 PaTHway open-label trial extension demonstrated sustained efficacy, safety, and tolerability in a 1-year analysis.

MedScape 12 November at 04.30 AM

How to Manage Patients on GLP-1s Before Surgery?

An FDA label change and consensus guidance notwithstanding, endocrinologists seem to have made up their minds on how to handle patients on GLP-1s at high risk for aspiration.

MedScape 12 November at 02.40 AM

Precautions Needed to Prevent Hematoma After Thyroid Surgery

Poorly controlled blood pressure among key risk factors in rare but potentially lethal neck hematomas occurring after thyroidectomy.

MedScape 11 November at 10.08 AM

Doctors Caution Over Weight Loss Drug Link to Nurse's Death

Use of the weight loss drug tirzepatide was noted on the death certificate of a Scottish nurse, but experts say clinical trials have demonstrated an acceptable safety record.

MedScape 11 November at 08.09 AM

‘Round Face’: A Viral Term’s Real Diagnostic Implications

Popular videos and social media posts have identified cortisol as the main culprit behind facial puffiness, but many disorders can underlie such symptoms. Here’s how to diagnose them.

MedScape 11 November at 06.55 AM

Oral Semaglutide 25-mg Dose May Provide Most Benefit

Lower dose appears equivalent to 50 mg oral and 2.4 mg injected for weight loss and other outcomes.

MedScape 11 November at 05.02 AM

US Minority Veterans Face Unequal Access to Ozempic and Wegovy, Study Finds

U.S. military veterans face racial and ethnic inequities in access to Novo Nordisk's highly in-demand drugs for diabetes and weight loss, according to a review of patient...

MedScape 08 November at 07.17 AM

Update Coming for Thyroid Disease in Pregnancy Guidelines

The first pregnancy guideline updates from the American Thyroid Association since 2017 to emphasize shared decision-making, key treatment/testing recommendation changes.

MedScape 08 November at 05.52 AM

Do Patients on Anti-Obesity Drugs Decrease Alcohol Use?

Nearly half reported decreased drinking after initiating any anti-obesity medication, including second-generation GLP-1 receptor agonists.

HealthDay 07 November at 04.22 PM

Expanding Access to Obesity Medications Could Avert 42,000 Deaths/Year

Expanding access to obesity medications such as glucagon-like peptide 1 (GLP-1) receptor agonists and dual gastric inhibitory polypeptide and GLP-1 receptor agonists could avert 42,000 deaths annually in the United States, according to a study published online Oct. 15 in the Proceedings of the National Academy of Sciences.Abhishek Pand

HealthDay 07 November at 04.02 PM

In-Utero Sugar Restriction Cuts Offspring's Risk for Diabetes, Hypertension

Sugar restriction during the first 1,000 days after conception lowers a child's risk for later developing type 2 diabetes and hypertension, according to a study published online Oct. 31 in Science.Tadeja Gracner, Ph.D., from the University of Southern California in Los Angeles, and colleagues examined the impact of sugar exposure

HealthDay 07 November at 12.24 PM

Novo Nordisk CEO Warns of Deaths Linked to Compounded Semaglutide

The head of the company that makes the diabetes and obesity drugs Ozempic and Wegovy has warned that compounded versions of the active ingredient in those medications have now been linked to at least 100 hospitalizations and 10 deaths.“Honestly, I’m quite alarmed by what we see in the U.S. now,” Novo Nordisk President and CEO <a href="https://w

MedScape 07 November at 06.40 AM

Changing Concepts in Hyperthyroidism Management

US endocrinologists are favoring antithyroid drugs over radioactive iodine in initial Graves’ disease treatment, and new investigational agents may change clinical management further.

MedScape 07 November at 06.00 AM

Awakening to the Dawn Phenomenon in Diabetes

Early morning hyperglycemia is sometimes called the “dawn phenomenon.” Left untreated, it can drive poorer outcomes. How can it be detected and managed?

HealthDay 06 November at 05.11 PM

Prevalence of Diabetes 15.8 Percent in U.S. Adults From 2021 to 2023

The prevalence of diabetes was 15.8 percent among U.S. adults during August 2021 to August 2023, according to a November data brief published by the National Center for Health Statistics.Jane A. Gwira, M.D., M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from the National Health and Nu

MedScape 06 November at 07.06 AM

Knowledge Gaps About Obesity Medicine Seen in Primary Care

Survey at a safety net hospital finds that not all providers are knowledgeable about, or feel comfortable with, providing comprehensive obesity care.

MedScape 06 November at 07.05 AM

Early-Life Sugar Restriction Reduces T2D, Hypertension Risk

Sugar restriction during pregnancy and in early childhood delayed the onset of type 2 diabetes and hypertension by about 4 and 2 years, respectively, found a natural experiment in sugar rationing.

MedScape 06 November at 05.54 AM

Novo Nordisk Affirms 25% Weight-loss Expectation for Experimental Drug CagriSema

Novo Nordisk said the side effects in trials so far for its experimental obesity drug CagriSema were similar to its GLP-1 drugs already on the market, and reiterated its...

MedScape 06 November at 03.13 AM

Novo Nordisk Aware Of Reports 10 People Taking Compounded Weight-loss Drug Copies Died

Novo Nordisk said on Wednesday it was aware of reports of 10 deaths and 100 hospitalisations of people who had taken compounded copies of its weight-loss and diabetes...

MedScape 06 November at 02.26 AM

Diagnosing and Managing Thyroid Eye Disease

A joint presentation by an endocrinologist and ophthalmologist reviewed best practices for managing thyroid eye disease, including when to refer to an ophthalmologist and what tests to run.

MedScape 06 November at 02.07 AM

FDA Updates GLP-1 Label With Pulmonary Aspiration Warning

The new warning affects labels for drugs made with semaglutide, liraglutide, and tirzepatide.

MedScape 06 November at 02.07 AM

FDA Updates GLP-1 Label with Pulmonary Aspiration Warning

The new warning affects labels for drugs made with semaglutide, liraglutide, and tirzepatide.

MedScape 05 November at 11.27 AM

Tirzepatide Slashes Progression From Prediabetes to T2D

At 3 years in SURMOUNT-1, more than 90% of people remained diabetes-free with tirzepatide and maintained their initial weight loss, but the benefits reverted after the drug was stopped.

HealthDay 05 November at 11.04 AM

Medicaid Covers GLP-1 Meds for Obesity in Just 13 States

Low-income patients' access to blockbuster weight-loss drugs through Medicaid remains limited, a new KFF analysis has found.Only 13 states currently allow Medicaid to cover treatment of obesity using glucagon-like peptide-1 agonist (GLP-1) medications, researchers discovered.Under the Medicaid system, individual states are allowed to deci

MedScape 05 November at 09.00 AM

Fasting Requirement for Levothyroxine Presents Challenges

The survey found that two thirds of patients do not adhere, and half say postponing breakfast was burdensome for them.

MedScape 05 November at 05.00 AM

Coming Soon: A New Disease Definition, ‘Clinical Obesity’

A document to be published in Lancet Diabetes & Endocrinology will redefine obesity as a condition of excess adiposity, and “clinical obesity” as a disease.

MedScape 05 November at 04.30 AM

Topiramate Plus Metformin Effective for Weight Loss in PCOS

A combination of metformin and topiramate along with a low-calorie diet was an effective, low-cost weight loss strategy in women with polycystic ovary syndrome.

HealthDay 04 November at 11.44 PM

Policies About Late-Career Physicians Are Considered Successful

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

HealthDay 04 November at 11.41 PM

Improvement Seen in Some Features of PCOS With Weight Loss Interventions

Weight loss interventions are associated with improvement in some features of polycystic ovary syndrome (PCOS), according to a study published online Nov. 5 in the Annals of Internal Medicine.Jadine Scragg, Ph.D., from the University of Oxford in the United Kingdom, and colleagues quantified the effect of weight loss interventions on cli

MedScape 04 November at 08.03 AM

Semaglutide 2.4 mg Reduces All-Cause Hospital Admissions

A new analysis from Novo Nordisk’s SELECT trial points to the potential for cost savings.

MedScape 04 November at 07.20 AM

Batoclimab Shows Rapid Effect on Key Graves’ Disease Markers

A preliminary study showed first evidence of normalization of T3, T4, within weeks, with additional thyroid eye disease effects.

MedScape 04 November at 06.03 AM

Analysis-Americans Hungry for Weight-loss Drugs Grapple With Supply and Insurance Hurdles

Americans are still eagerly seeking prescriptions for Eli Lilly and Novo Nordisk's weight-loss and diabetes drugs but cannot always fill them because of supply issues and...

MedScape 04 November at 03.55 AM

Newer Abbott Libre CGM Sensor Use Now Okay During Imaging

The US Food and Drug Administration has okayed removal of the contraindication for use during CT and MRI under certain conditions.

HealthDay 01 November at 04.17 PM

ASN: 1990 to 2021 Saw Global Rise in Chronic Kidney Disease Cases, Deaths in Women

Chronic kidney disease (CKD) cases and deaths in women surged worldwide between 1990 and 2021, according to a study presented at Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to 27 in San Diego.Sree Abhilekha Purohit, M.B.B.S., from the Shadan Institute of Medical Sciences in Hyderabad, India, and collea

HealthDay 01 November at 04.11 PM

Vasomotor Symptoms During Menopause May Up Risk for Type 2 Diabetes

Vasomotor symptoms (VMS) during the menopause transition (MT) are associated with an increased risk for type 2 diabetes (T2D), according to a research letter published online Oct. 31 in JAMA Network Open.Monique M. Hedderson, Ph.D., from Kaiser Permanente in Pleasanton, California, and colleagues examined the associations of frequency an

HealthDay 01 November at 03.46 PM

Semaglutide Linked to Reduced Risk for Alzheimer Diagnosis in T2DM

For patients with type 2 diabetes mellitus, semaglutide is associated with a reduced risk for a first-time Alzheimer disease (AD) diagnosis compared with other antidiabetic medications, according to a study published online Oct. 24 in Alzheimer's &amp; Dementia.William Wang, from the Case Western Reserve University School of Medicine in

HealthDay 01 November at 03.41 PM

ACG: GLP-1 RAs Tied to Lower Risk for Early-Onset Colorectal Cancer

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can decrease the risk for developing early-onset colorectal cancer (EO-CRC) in patients with diabetes regardless of weight, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Temitope Olasehinde, M.D., from

MedScape 01 November at 01.54 PM

Updates on Risk, Diagnosis, and Treatment of Thyroid Cancer

A session on thyroid cancer had updates on the risk of thyroid cancer with GLP-1 RA use; malignancy in Bethesda III, IV nodules; and treatment of RET-Mutated Medullary and TRK-Fusion Thyroid Cancer.

MedScape 31 October at 08.09 PM

How Asian Pharma Suppliers Cash in on Ozempic Copies

Just over a year ago, New Zealand customs officials started to intercept batches of injectable medications labelled Fitaro and Orsema, developed by a little-known...

MedScape 31 October at 04.53 PM

FDA Advisers Vote Against Lexicon Pharma's Add-on Drug for Type 1 Diabetes

Independent advisers to the U.S. Food and Drug Administration on Thursday voted against recommending Lexicon Pharmaceuticals' add-on treatment to insulin therapy for...

MedScape 31 October at 11.35 AM

Diwali Delights: Enjoying Festivities With Diabetes in Mind

The Hindu festival of lights is a time for families and friends to celebrate together, but some of the plentiful food on offer comes with health challenges.

MedScape 31 October at 06.10 AM

Vitamin D Aids Bones in Erythropoietic Protoporphyria

Compared with the general population, patients with erythropoietic protoporphyria have notably lower bone mineral density, although it improved with cholecalciferol supplementation.

MedScape 31 October at 05.58 AM

GLP-1 Use Presurgery Safe but No Weight Loss Boost

Use of a GLP-1 RA before bariatric surgery is likely safe, but unlikely to boost weight loss.

HealthDay 30 October at 03.42 PM

Potential Genetic Link ID'd Between Thyroid Disease, Alopecia Areata

There seems to be a significant association between hypothyroidism, Hashimoto thyroiditis, subacute thyroiditis, and alopecia areata (AA), according to a study published in the October issue of Skin Research &amp; Technology.Yue Zhao, from Heping Hospital Affiliated to Changzhi Medical College in China, and colleagues examined the po

HealthDay 30 October at 03.40 PM

AI Can Help ID Patients With Diabetes at Highest Risk for Cardiomyopathy

Machine learning can he;p identify individuals with diabetes at high risk for diabetic cardiomyopathy (DbCM), according to a study published online Sept. 6 in the&nbsp;European Journal of Heart Failure.Matthew W. Segar, M.D., from the Texas Heart Institute in Houston, and colleagues developed and validated a machine learning-based cl

HealthDay 30 October at 03.33 PM

Small but Important Differences Seen Between Rosuvastatin, Atorvastatin

There are small but important differences in risk for some clinical outcomes associated with rosuvastatin and atorvastatin, according to a study published online Oct. 29 in&nbsp;Annals of Internal Medicine.Shiyu Zhou, M.D., from Southern Medical University in Guangzhou, China, and colleagues compared the real-world effectiveness and

MedScape 30 October at 11.31 AM

Can Fish Skin Grafts Heal Diabetic Foot Ulcers?

Intact fish skin grafts could be an effective treatment for wound closure in patients with severe types of diabetic foot ulcers, showed a clinical trial.

MedScape 30 October at 09.48 AM

Thyroid Cancer Overdiagnosis Continues Despite Cautions

A new study shows overdiagnosis of thyroid cancer continuing despite efforts to curb screening in asymptomatic patients.

MedScape 30 October at 04.56 AM

Should the Body Roundness Index Replace BMI?

BMI is a quick and convenient tool for assessing weight-related health risks, but some researchers back replacing it with an index of body roundness.

HealthDay 29 October at 10.50 PM

Many Seniors at Risk for Financial Precarity From Cost of Hospital Stay

Many Medicare beneficiaries are at risk for financial hardship from the costs of a single hospital stay, according to a study published online Oct. 29 in the Annals of Internal Medicine.Paula Chatterjee, M.D., M.P.H., from the University of Pennsylvania Perelman School of Medicine, and colleagues identified beneficiaries who would face

HealthDay 29 October at 03.48 PM

Trends in Obesity Treatment Show Surge in GLP-1 RAs, Drop in Surgeries

Among privately insured patients, there was a doubling in the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as antiobesity treatment from 2022 to 2023, with a simultaneous 25.6 percent decrease in the rate of metabolic bariatric surgery, according to a research letter published online Oct. 25 in&nbsp;JAMA Network Open.Ke

MedScape 29 October at 10.00 AM

Early T2D Diagnosis Heightens Risks for Complications, Death

Those diagnosed with type 2 diabetes when younger than 40 years of age had greater risks for several diabetes-related outcomes.

MedScape 29 October at 09.54 AM

American Diabetes Association Advises on Hospital CGM Use

A new consensus statement offers “considerations and good practice points” for the use of continuous glucose monitoring systems in hospital settings.

MedScape 29 October at 08.37 AM

Opioids May Harm Reproductive, Bone, Adrenal Hormone Health

Opioid use and misuse have negative effects on the endocrine system and can lead to hypothalamic-pituitary system and bone health complications.

MedScape 29 October at 07.12 AM

Obesity Week 2024 Tackles Treatment, Prevention and Access

Agenda features new trial results on GLP-1 agonists, along with obesity complications, obesity prevention starting in childhood, and improving access to obesity treatment.

HealthDay 28 October at 03.39 PM

2010 to 2023 Saw Increase in GLP-1 RA, SGLT2 Inhibitor Use in Type 1 Diabetes

From 2010 to 2023, there was an increase in prescribing of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and sodium glucose cotransporter 2 (SGLT2) inhibitors among individuals with type 1 diabetes (T1D), according to a research letter published online Oct. 23 in the Journal of the American Medical Association.Piaopiao Li, from

MedScape 28 October at 09.11 AM

Battle Continues Over Compounded GLP-1s

Novo Nordisk seeks to put a stop to semaglutide compounding, whereas the FDA agrees to allow compounding of tirzepatide, for now.

MedScape 28 October at 06.46 AM

Anti-Obesity Drugs Show Whole-Body Promise and More Is Ahead

Popular GLP-1 drugs are already known to have many benefits, but scientists continue to explore what else they — and their soon-to-be-successors — may also do.

HealthDay 25 October at 03.51 PM

Eucaloric Carbohydrate-Restricted Diet Improves β-Cell Function in T2DM

A eucaloric carbohydrate-restricted (CR) diet improves β-cell response to glucose in patients with type 2 diabetes (T2D), according to a study published online Oct. 22 in the Journal of Clinical Endocrinology &amp; Metabolism.Barbara A. Gower, Ph.D., from the University of Alabama at Birmingham, and colleagues examined whether a eucalor

MedScape 25 October at 12.36 PM

MHRA Warns of Weight Loss Drug Side Effects

Healthcare professionals are being asked to report obesity jab misuse, while the House of Lords has called for a junk food advertising ban.

MedScape 25 October at 08.42 AM

Does Exercise Intensity Modulate Ghrelin?

High-intensity exercise may be more effective than moderate-intensity exercise in suppressing ghrelin levels and modifying hunger, with women showing the most response.

HealthDay 24 October at 03.31 PM

Duodenal ReCET Plus Semaglutide Can Prevent Need for Insulin in T2DM

For patients with type 2 diabetes (T2D), duodenal recellularization via electroporation therapy (ReCET), which uses pulsed electric fields to induce natural cell death through an apoptosis-like process, is feasible and safe and can prevent the need for insulin therapy when combined with semaglutide, according to a study presented at UEG Week, the ann

MedScape 24 October at 09.54 AM

Rise in GLP-1 RA and SGLT2i Prescribing in Patients With T1D

An analysis of over 400,000 patients with T1D revealed a rise in prescribing for glucagon-like peptide 1 receptor agonists and sodium-glucose cotransporter 2 inhibitors over the past decade.

MedScape 24 October at 09.05 AM

Oral Semaglutide May Boost Liver Health in Type 2 Diabetes

Oral semaglutide improved liver health, diabetes status, and lipid profile in patients with MASLD and T2D, with weight loss likely playing a role, showed a prospective study.

HealthDay 23 October at 03.50 PM

AAO: Prior Intravitreal Injections Increase Risk for Cataract Surgery Complications

A&nbsp;history of multiple past intravitreal injections (IVIs) poses a risk for certain future cataract surgery complications, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Oct. 18 to 21 in Chicago.Winnie Yu, from the University of Toronto, and colleagues used physician billing and di

HealthDay 23 October at 03.09 PM

FDA Appoints New Head of Medical Devices

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

MedScape 23 October at 09.47 AM

Can Restricting Carbs Cut the Need for Medication in T2D?

Following a low-carbohydrate diet raised C-peptide levels, with a greater increase observed in African Americans.

MedScape 23 October at 05.04 AM

US Medicaid Programs Say Cost a Key Factor for Weight-loss Drug Coverage, Survey Finds

Most U.S. states do not currently cover highly sought after weight-loss drugs from Novo Nordisk and Eli Lilly in their Medicaid health programs for low income people, citing...

MedScape 22 October at 08.36 AM

Topline: Oral Semaglutide Cuts Cardiovascular Events in T2D

In Novo Nordisk’s randomized clinical trial, semaglutide reduced the risk for major adverse cardiovascular events by 14% compared with placebo.

MedScape 22 October at 06.32 AM

US FDA Declines to Approve Camurus' Rare Hormone Disorder Drug

The U.S. Food and Drug Administration has declined to approve Camurus' drug for the treatment of a rare hormonal disorder due to deficiencies at a third-party manufacturing...

MedScape 21 October at 10.22 AM

How Are Doctors Using Tirzepatide vs Semaglutide? A Q&A

Physicians consider a patient’s overall health, how much weight needs to be lost, and potential side effects in making a choice.

MedScape 21 October at 09.08 AM

A Single Jog Can Improve Glucose Metabolism in Young Adults

A single 30-minute session of aerobic exercise led to improved glucose metabolism and insulin sensitivity in healthy young adults 1 day later.

MedScape 21 October at 05.02 AM

Lilly Sues Online Vendors, Medical Spa Over Copycat Weight-loss Drugs

Eli Lilly said on Monday it sued three medical spas and online vendors for selling products claiming to contain tirzepatide, the main ingredient in its popular weight-loss...

HealthDay 18 October at 10.07 PM

Comorbid Diabetes Increases Risk for Lower Extremity Amputation With Kidney Disease

Patients with comorbid diabetes have an elevated risk for lower extremity amputation (LEA) at all stages of chronic kidney disease (CKD) compared with patients without diabetes, according to a study published online in the November issue of Journal of Diabetes and Its Complications.Dhruv Nandakumar, from University of Texas Southwestern

MedScape 18 October at 08.42 AM

Metformin After Bariatric Surgery: Necessary or Not?

Continuing metformin after bariatric surgery did not provide additional benefits for glycemic control or weight reduction in patients with obesity and type 2 diabetes, a retrospective study found.

MedScape 17 October at 03.46 PM

Medtronic Warns of Battery Problem With Insulin Pumps

In a second letter to users of MiniMed 600 and 700 series insulin pumps, the company advises patients to carry backup batteries and change them immediately when “low battery pump” alert appears.

HealthDay 17 October at 03.39 PM

Paternal Metformin Use Does Not Increase Risk for Congenital Malformations

Paternal metformin use during the period of sperm development is not associated with an increased risk for congenital malformations in offspring, according to a study published online Oct. 16 in The BMJ.Lin-Chieh Meng, from the National Taiwan University, and colleagues examined the association between paternal metformin use and the r

MedScape 17 October at 07.58 AM

Pediatric Obesity and MASLD: A Risky Combination for T2D

MASLD in pediatric obesity was linked to an increased risk for youth-onset type 2 diabetes, especially in the presence of intermediate hyperglycemia.

MedScape 17 October at 03.42 AM

T2D More Prevalent Than T1D Among Adolescents in Some Areas

Adolescents with type 2 diabetes have a higher incidence of complications than adults with type 2 diabetes or adolescents with type 1 diabetes.

HealthDay 16 October at 02.46 PM

Risk for Type 2 Diabetes Increased for Children After SARS-CoV-2 Infection

The risk for an incident diagnosis of type 2 diabetes (T2D) is increased in the six months following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online Oct. 14 in JAMA Network Open.Margaret G. Miller, from the Case Western Reserve University School of Medicine in Cleveland, a

MedScape 16 October at 10.28 AM

Insulin Pump Glitches: A Call to End Daylight Saving Time?

Even the most savvy patients with diabetes can err in adjusting insulin pumps for US seasonal time shifts, adding to the evidence supporting ending these biannual clock changes.

MedScape 16 October at 09.52 AM

Automated Insulin Delivery Systems Reduce Burden in Diabetes

Automated insulin delivery systems not only improved glycemic endpoints but also alleviated disease burden and enhanced quality of life in patients with diabetes, a meta-analysis showed.

HealthDay 15 October at 03.56 PM

Reported Dietary Intake Linked to Inflammation for >50 Percent of Adults

More than half of U.S. adults report 24-hour dietary intakes associated with inflammation, according to a study published online Sept. 27 in Public Health Nutrition.Rachel J. Meadows, Ph.D., from the Center for Epidemiology &amp; Healthcare Delivery Research in Fort Worth, Texas, and colleagues examined sociodemographic differences in

HealthDay 15 October at 12.32 PM

FDA Says Compounding Pharmacies Can Keep Making Weight-Loss Med Tirzepatide, for Now

Pharmacists may continue making compounded versions of the weight-loss medication tirzepatide while the U.S. Food and Drug Administration revisits its Oct. 2 decision to remove the medicine from a national drug shortage list.What prompted the FDA to reconsider its <a href="https://www.fda.gov/drugs/drug-safety-and-availability/fda-clarifies-pol

MedScape 15 October at 09.38 AM

Obesity Therapies: What Will the Future Bring?

Comprehensive outcome measures, combination therapies, and cause-based treatments are on the horizon.

MedScape 15 October at 09.35 AM

Dietary Fats May Protect Against Thyroid Autoimmunity

Lower consumption of dietary fats was associated with thyroid autoimmunity in men but not in women, according to an analysis of a large nationally representative US dataset.

MedScape 15 October at 08.21 AM

Indigenous Mexicans With Diabetic Foot Face Delays in Care

Historical discrimination, lack of qualified interpreters, and inadequate access to care contribute to worse outcomes among Indigenous patients with diabetes.

MedScape 15 October at 05.40 AM

Urinary Calcium: A Marker of Bone Health in Youth With T1D?

Greater urinary calcium excretion was associated with reduced bone accrual in youth with type 1 diabetes, found an observational study.

MedScape 14 October at 08.07 AM

Why a Diabetes Drug Fell Short of Anticancer Hopes

Metformin, commonly used to treat diabetes, has been investigated for treating a range of cancer types in thousands of studies on laboratory cells, animals, and people.

MedScape 14 October at 07.27 AM

Genetic High Cholesterol Condition Poses Diabetes Risk

A new study found that risk factors for diabetes in patients with the genetic condition are the same as for those in the general population.

MedScape 14 October at 06.08 AM

Thyroid Cancer Recurrence Definitions Still Lack Consensus

This systematic review of 70 studies highlighted the lack of a universally accepted definition for recurrence of differentiated thyroid cancer across different treatment categories.

MedScape 14 October at 04.40 AM

Can Green Spaces Save Lives in Type 2 Diabetes?

Increasing green infrastructure in residential areas may greatly benefit individuals with T2D by mitigating harmful pollutants, according to a large prospective study conducted in China.

HealthDay 11 October at 09.07 PM

Letter Nudges Increase Likelihood of Flu Vaccination for Adults With Chronic Diseases

For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association.Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital -- Herlev a

HealthDay 11 October at 03.53 PM

Industry Payments Common for Physician Peer Reviewers of Top Journals

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

MedScape 11 October at 08.59 AM

Metabolic-Bariatric Surgery Reduces Pancreatic Cancer Risk

Effect appeared more pronounced among those with type 2 diabetes.

HealthDay 10 October at 03.50 PM

Preschool Outdoor Play Time Tied to Lower Risk for Later Obesity

Outdoor play habits in early preschool years are associated with a lower risk for school-age obesity, according to a study published online Oct. 9 in&nbsp;Acta Paediatrica.Takahiro Tsuge, from the Graduate School of Medicine, Dentistry and Pharmaceutical Sciences at Okayama University in Japan, and colleagues investigated the associat

MedScape 10 October at 10.24 AM

Is Thyroid Cancer a 'Good' Cancer? Experts & Patients Say No

Although papillary thyroid cancer outcomes generally are good, the disease can still be life-altering for years to come.

MedScape 10 October at 09.36 AM

Low Lipids Linked to Thyroid Cancer Recurrence

Triglyceride and HDL cholesterol levels before thyroid cancer surgery, integrated with several pathologic factors, may help predict the recurrence rate of papillary thyroid cancer.

MedScape 10 October at 07.55 AM

CGM With Geriatric Care Simplifies T1D Management in Seniors

Continuous glucose monitoring enhanced by geriatric care principles reduced the duration of hypoglycemia without worsening glycemic control in older adults with T1D.

HealthDay 09 October at 04.06 PM

Metabolic-Bariatric Surgery Tied to Reduced Risk for Pancreatic Cancer in Those With Obesity

For individuals with obesity, metabolic-bariatric surgery (MBS) is associated with a reduced risk for pancreatic cancer, especially among those with type 2 diabetes (T2D), according to a review published online Oct. 9 in Diabetes/Metabolism Research and Reviews.Angeliki M. Angelidi, M.D., Ph.D., from the Broad Institute of MIT and Har

MedScape 09 October at 08.48 AM

Metformin: An Unexpected Ally Against Long COVID?

Adults with type 2 diabetes using metformin had a slightly lower risk of dying or developing long COVID within 180 days after SARS-CoV-2 infection than those using other diabetes medications.

MedScape 08 October at 09.56 AM

Eggs: A Weighty Matter for Postmenopausal Women?

Postmenopausal women who ate more eggs or egg nutrients were more likely to gain weight, especially those following a Western diet.

MedScape 08 October at 09.08 AM

How Are Ultra-Processed Foods Fueling the Obesity Epidemic?

Consumption of UPFs increased body weight and energy intake in overweight and obese young men, found a small study implicating less chewing per calorie.

MedScape 08 October at 09.00 AM

Ultrasound Alone Can Diagnose Most Thyroid Nodules

Findings confirmed guidelines, but also suggested further investigation to be undertaken for non-diagnostic and atypical nodules.

MedScape 08 October at 04.45 AM

Vitamin D in Pregnancy Results in Stronger Bones for Kids

Supplementation with 1000 IU/d cholecalciferol from 14-17 weeks' pregnancy until delivery resulted in higher offspring bone mineral density at age 4 years that persists to age 6-7 years.

HealthDay 07 October at 09.21 PM

Metabolic Risk Contributes to Diabetes Onset in People With HIV

For people with HIV (PWH) with low-to-moderate atherosclerotic cardiovascular disease (ASCVD) risk, metabolic risk factors contribute to new-onset diabetes mellitus (DM) among those treated with pitavastatin or placebo, according to a study published online Oct. 8 in the Annals of Internal Medicine.Kathleen V. Fitch, from Massachusetts G

HealthDay 07 October at 03.41 PM

Tobacco-Free Generation Could Prevent 40 Percent of Predicted Lung Cancer Deaths Globally

Implementation of a tobacco-free generation could substantially reduce global lung cancer mortality, according to a study published in the October issue of&nbsp;The Lancet Public Health.Julia Rey Brandariz, Ph.D., from the Universidade de Santiago de Compostela in Spain, and colleagues estimated the impact of eliminating tobacco smoking

MedScape 07 October at 11.25 AM

Ghost Fat: The Unseen Consequences of Weight Loss

Some people who have lost weight don't perceive their leaner selves in the mirror and remain dissatisfied with their bodies. What drives this experience, and how can it be treated?

MedScape 07 October at 08.18 AM

EU Program Aims to Ensure Safety for Pilots Who Use Insulin

The program is examining the effectiveness of a protocol meant to ensure safety for pilots and air traffic controllers on insulin.

MedScape 07 October at 03.36 AM

Tirzepatide Shortage Resolved? FDA Says Yes, Compounders No

Tirzepatide injection (Zepbound, Mounjaro) is officially off the FDA's drug shortage list, meaning compounders can no longer prepare and dispense the drug.

HealthDay 04 October at 03.30 PM

Accelerating Smoking Elimination Could Prevent Millions of Deaths by 2050

A substantial smoking-attributable burden can be avoided by accelerating the pace of smoking elimination, according to a study published in the October issue of The Lancet Public Health.Stein Emil Vollset, M.D., M.P.H., from the Norwegian Institute of Public Health in Bergen, and fellow GBD 2021 Tobacco Forecasting Collaborators used the

HealthDay 03 October at 10.14 PM

CDC: Counterfeit Drugs From Online Pharmacies Pose Considerable Danger

Counterfeit medications from online pharmacies pose significant risks to patients, including overdose and death, according to a warning issued by the U.S. Centers for Disease Control and Prevention.The warning follows a federal indictment announced last week again

HealthDay 03 October at 03.23 PM

Progress Toward Cutting Racial Mortality Disparities Stalling, Reversing

U.S. racial disparities in mortality decreased from 1999 to 2015 for Black men and to 2011 for Black women, followed by stagnation or regression, according to a study published online Sept. 30 in&nbsp;JAMA Network Open.Adith S. Arun, from the Yale School of Medicine in New Haven, Connecticut, and colleagues sought to compare excess age

MedScape 03 October at 09.43 AM

Cannabis Use Rising in Diabetes: What Do Endos Need to Know?

With little in the way of evidence or professional guidance, endocrinologists have been left on their own when it comes to advising patients.

MedScape 03 October at 08.12 AM

First Patient-Derived Stem Cell Transplant a Success in T1D

At 1 year, islets chemically reprogrammed from the patient's own somatic cells allowed them to become insulin-independent with the use of immunosuppression.

MedScape 03 October at 05.43 AM

Hypothyroidism Treatment Does Not Affect Cognition in Women

In menopausal women, hypothyroidism treatment with levothyroxine was not linked to cognitive function decline, highlighting the need to investigate other causes.

MedScape 03 October at 03.48 AM

Monitoring May Reduce Nerve Injury Risk in Thyroidectomy

A review of data from a large cohort of patients undergoing thyroidectomy identified risk factors for laryngeal nerve injury.

HealthDay 01 October at 03.49 PM

Gestational Diabetes Risk Higher in Women With Preconception Prediabetes

Preconception prediabetes is associated with increased odds of gestational diabetes among adolescents and young adults, according to a study published online Sept. 24 in JAMA Network Open.Katharine J. McCarthy, Ph.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues conducted a retrospective cohort study

HealthDay 01 October at 03.46 PM

Premature Ovarian Insufficiency Linked to Autoimmune Diseases

Women diagnosed with premature ovarian insufficiency (POI) have an increased prevalence of severe autoimmune diseases, according to a study published online Sept. 25 in Human Reproduction.Susanna M. Savukoski, M.D., from Oulu University Hospital in Finland, and colleagues conducted a population-based registry study of 3,972 women diagno

MedScape 01 October at 09.50 AM

Does Metformin Therapy Impact CVD in T2D? It's Complicated

Metformin plus lifestyle interventions can prevent diabetes in people with impaired glucose tolerance, treat type 2 diabetes and prediabetes, and by extension could help reduce cardiovascular disease — maybe.

MedScape 01 October at 09.32 AM

New Guidelines Emphasize Liver Care in T2D, Obesity

Updated European guidelines for metabolic dysfunction–associated steatotic liver disease stressed a higher risk in people with type 2 diabetes and/or obesity plus at least one metabolic risk factor.

MedScape 01 October at 09.00 AM

Does Screening Prevent Diabetic Foot Complications?

Available data are insufficient to answer the question.

MedScape 01 October at 06.34 AM

COVID-19 Raises Hypertension and Kidney Disease Risk in T1D

Following SARS-CoV-2 infection, patients with T1D were at an increased risk of developing hypertension, CKD, and DKA, said a study with up to 40 months of follow-up.

HealthDay 30 September at 10.24 PM

Time-Restricted Eating Improves Glycemic Regulation in Metabolic Syndrome

Time-restricted eating (TRE), limiting dietary intake to eight to 10 hours without mandating calorie restriction, combined with standard-of-care (SOC) nutritional counseling improves glycemic regulation among adults with metabolic syndrome (MetS), according to a study published online Oct. 1 in the Annals of Internal Medicine.Emily N.C

HealthDay 27 September at 04.10 PM

Type 2 Diabetes Incidence Up With Higher Intake of Ultraprocessed Food

A higher intake of ultraprocessed food (UPF) is associated with an increased incidence of type 2 diabetes mellitus, according to a study published online Sept. 16 in The Lancet Regional Health.Samuel J. Dicken, from University College London, and colleagues conducted a prospective cohort analysis of the European Prospective Investigati

HealthDay 27 September at 04.07 PM

Casual Blood Glucose Testing Misses ~70 Percent of Gestational Diabetes Cases

Casual blood glucose (CBG) testing at 24 to 28 gestational weeks misses about 70 percent of women with gestational diabetes mellitus (GDM), according to a study published online Sept. 18 in the Journal of Diabetes Investigation.Masako Tomimoto, M.D., from the Kobe University Graduate School of Medicine in Japan, and colleagues enrolled

HealthDay 27 September at 04.03 PM

Metabolic Surgery Is Renoprotective in Patients With Obesity, CKD

For patients with obesity, type 2 diabetes, and estimated glomerular filtration rate (eGFR) 20 to 60 mL/min/1.73 m2, metabolic surgery is associated with a lower risk for progression of kidney impairment compared with glucagon-like peptide-1 receptor agonist (GLP-1RA) treatment, according to a study published in the September issue of the <

MedScape 27 September at 09.37 AM

Air Travel Alters Insulin Pump Delivery on Takeoff, Landing

Air bubble formation from pressure changes causes the pump to deliver about 0.6 extra units on ascent and about 0.5 less on descent.

MedScape 27 September at 06.18 AM

Young Adults With T1D Benefit From Tailored Support Program

A support program tailored to the needs of young adults with T1D was found to reduce hospitalizations and improve glycemic control when compared with usual endocrine care.

MedScape 27 September at 06.18 AM

Young Adults With T1D Benefit from Tailored Support Program

A support program tailored to the needs of young adults with T1D was found to reduce hospitalizations and improve glycemic control when compared with usual endocrine care.

MedScape 26 September at 09.45 AM

Diabetes Treatment May Lower Incidence of Uterine Fibroids

The risk for uterine fibroids in midlife women seemed to decrease in those receiving diabetes treatment but varied based on menopausal status.

HealthDay 25 September at 03.47 PM

Semaglutide May Lower Risk for Opioid Overdose in T2DM, Opioid Use Disorder

For patients with type 2 diabetes (T2D) and opioid use disorder (OUD), semaglutide is associated with a significantly lower risk for opioid overdose compared with other antidiabetic medications, according to a research letter published online Sept. 25 in JAMA Network Open.William Wang, from the Case Western Reserve University School

HealthDay 25 September at 11.31 AM

Novo Nordisk CEO Grilled by Congress Over Price of Ozempic

During a tense hearing before a Senate committee on Tuesday, Novo Nordisk CEO Lars Fruergaard Jørgensen faced tough questions over the company's high prices for its blockbuster drugs Ozempic and Wegovy.While testifying before the Senate Commit

MedScape 25 September at 09.50 AM

Diabetes Registries Could Help Address Wobbly Data Dilemma

Pan-European diabetes data registries need infrastructure and funding to ensure optimal decision-making in clinical practice, research, and policy.

MedScape 25 September at 07.56 AM

The Uneven Surge in Diabetes in the United States

The prevalence of diabetes in the United States increased by :

MedScape 25 September at 07.34 AM

Tirzepatide Leads to Long-Term Glucose Control

While several factors predict sustained glycemic control, predictors of sustained weight control with tirzepatide appear elusive, though women show greater weight reduction in general.

HealthDay 24 September at 11.02 PM

Prevalence of Obesity 40.3 Percent in U.S. From August 2021 to August 2023

The prevalence of obesity among adults was 40.3 percent during August 2021 to August 2023, according to a September data brief published by the National Center for Health Statistics.Samuel D. Emmerich, D.V.M., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from the National Health and Nutritio

HealthDay 24 September at 03.22 PM

Residing in Low-Income, Low Food-Access Neighborhoods Tied to Higher Child BMI

Residence in low-income, low food-access neighborhoods in early life is associated with higher subsequent child body mass index (BMI) and a higher risk for obesity, according to a study published online Sept. 16 in&nbsp;JAMA Pediatrics.Izzuddin M. Aris, Ph.D., from Harvard University in Boston, and colleagues examined associations of

MedScape 24 September at 09.50 AM

'Call to Action': Greater CVD Focus Urged for T1D

Several studies revealed high cardiovascular risk in people with type 1 diabetes, including in those who are asymptomatic and younger and with shorter diabetes duration.

MedScape 24 September at 12.01 AM

US Adult Obesity Prevalence Over 40%, Severe Obesity Over 9%

The prevalence of obesity and severe obesity was lower among those with a bachelor's degree vs those with some college or a high school diploma or less.

HealthDay 23 September at 10.30 PM

Extreme Temperature-Related Deaths Set to Increase by Mid-21st Century

Extreme temperature-related deaths are projected to increase considerably by the mid-21st century in the contiguous United States, according to a study published online Sept. 20 in JAMA Network Open.Sameed Ahmed M. Khatana, M.D., M.P.H., from the University of Pennsylvania Perelman School of Medicine in Philadelphia, and colleagues exa

HealthDay 23 September at 04.04 PM

Higher Burden of Comorbidity Linked to Worse Clinical Outcomes in MS

For people with multiple sclerosis (MS), a higher burden of comorbidity is associated with worse clinical outcomes, according to a study published online Sept. 18 in JAMA Neurology to coincide with the annual meeting of the European Committee for Treatment and Research in Multiple Sclerosis, held from Sept. 18 to 20 in Copenhagen, Denmark.</p

HealthDay 23 September at 03.58 PM

Study Looks at Impact of Peritoneal Dialysis on Thyroid Function

Patients undergoing peritoneal dialysis (PD) have significantly higher thyroxine (T4) concentrations than hemodialysis (HD) patients and higher free T4 (FT4) concentrations at 12 and 24 months, according to a study published online Sept. 7 in Seminars in Dialysis.Jelić Pranjić Ita, M.D., from the University Hospital Center Rijeka in Cr

HealthDay 23 September at 03.40 PM

Exposure to Toxic Metals Linked to Faster Increases in Glycemia

Exposure to toxic metals and alterations in essential metal homeostasis are associated with faster increases in glycemia over time in a high-risk Mexican American population, according to a study published online Sept. 15 in Diabetes Care.Margaret C. Weiss, from the University of Illinois at Chicago, and colleagues examined continuous

MedScape 23 September at 10.07 AM

FDA Clears AI-Powered Thyroid Ultrasound Analysis System

The See-Mode system is said to be the first of its kind in thyroid nodule detection and diagnosis.

MedScape 23 September at 05.42 AM

Does Bariatric Surgery Also Improve Thyroid Function?

Metabolic/bariatric surgery improved thyroid function and hormone resistance in patients with obesity, which was correlated with improvement in body composition.

MedScape 23 September at 05.21 AM

Insulin Therapy De-Escalation to Fixed-Ratio Combo Safe

The de-intensification from a multiple daily injection insulin regimen to once-daily iGlarLixi showed similar glucose control and greater weight loss without an increased risk for hypoglycemia.

MedScape 20 September at 09.08 AM

Healthy Lifestyle Mitigates Brain Aging in Diabetes

Diabetes, prediabetes, and hyperglycemia were linked to accelerated brain aging, but physical activity and abstention from smoking and heavy drinking may mitigate much of this effect.

MedScape 20 September at 08.24 AM

Semaglutide Bests Liraglutide in Long-Term Weight Loss

Researchers found that patients with obesity had an average weight loss of 12.9% with semaglutide vs 5.6% with liraglutide after 1 year.

MedScape 20 September at 07.52 AM

BMI in Both Partners Affects Fertility and Miscarriage Risk

"We observed in this cohort study that BMI outside of the normal category in women and men was associated with lower fecundability, subfertility, and increased odds of miscarriage."

MedScape 20 September at 06.48 AM

Canada Tackles PFAS: Is It Doing Enough?

PFAS are causing significant harm to the environment, people, pets, and wildlife, but it's not clear that proposed solutions and calls to action will make a difference.

HealthDay 19 September at 03.57 PM

Metformin Use Tied to Lower Incidence of Death, Long COVID After COVID-19

After severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, prevalent metformin use is associated with a slightly lower incidence of death or postacute sequalae of SARS-CoV-2 (PASC), according to a study published online Sept. 17 in Diabetes Care.Steven G. Johnson, Ph.D., from the University of Minnesota in Minneapo

HealthDay 19 September at 03.40 PM

Diabetes Complications Tied to Higher Risk for Gum Disease

Neuropathy and retinopathy are positively associated with moderate/severe periodontitis, according to a study published online Aug. 5 in the Journal of Dental Research.Fernando Valentim Bitencourt, D.D.S., from Aarhus University in Denmark, and colleagues investigated the association between individual and combined diabetic microvasc

MedScape 19 September at 03.38 PM

EU Regulator Backs Use Of Novo's Wegovy for Obesity-related Heart Condition

The European Medicines Agency backed the use of Novo Nordisk's popular drug Wegovy to help ease heart failure in people with obesity, the Danish drugmaker said on...

MedScape 19 September at 07.50 AM

Hyperglycemia Linked to Mortality in Older Adults With T2D

Time spent above, not below, the target glucose range was associated with mortality in a study of adults with type 2 diabetes aged 75 years or older.

MedScape 19 September at 07.06 AM

Bariatric Surgery, Weight Loss Makes Brain Say Meh to Sweets

Sugary beverages were less satisfying to participants after bariatric surgery and weight loss, found a recent observational study that examined the neural correlates of sweet taste.

MedScape 19 September at 05.55 AM

Fridays and Snacking Bad for Smart Insulin Pen Adherence

Poor adherence varies by day of week, age, and engagement with the connected pen/app.

HealthDay 18 September at 10.27 PM

SGLT2i Use Linked to Lower Risk for Neurodegenerative Disease in T2DM

For patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitor (SGLT2i) use is associated with reduced risks for incident dementia and Parkinson disease (PD), according to a study published online Sept. 18 in Neurology.Hae Kyung Kim, M.D., from the Yonsei University College of Medicine in Seoul, South Korea, and colleag

HealthDay 18 September at 03.56 PM

Caffeine, Coffee Linked to Lower Cardiometabolic Multimorbidity Risk

Habitual coffee or caffeine intake is associated with a lower risk for new-onset cardiometabolic multimorbidity (CM), according to a study published online Sept. 17 in the Journal of Clinical Endocrinology &amp; Metabolism.Xujia Lu, from the Suzhou Medical College of Soochow University in China, and colleagues examined the associati

HealthDay 18 September at 03.54 PM

Current National Prevalence of Diagnosed A-Fib, 10.55 Million

The prevalence of diagnosed atrial fibrillation (AF) in the United States is 4.48 percent among the adult population, according to a study published online Sept. 13 in the Journal of the American College of Cardiology.Jean Jacques Noubiap, M.D., Ph.D., from the University of California-San Francisco, and colleagues determined the co

MedScape 18 September at 10.08 AM

CGM Cuts Hospitalization in T2D, Even in Non-Insulin Treated

Real-world data showed reductions in healthcare resource utilization and improved glycemic control over 1 year with continuous glucose monitoring, regardless of treatment regimen.

HealthDay 18 September at 09.48 AM

Cost Has Many Going Around Doctors to Get Weight-Loss Medications

Wegovy, Zepbound and other cutting-edge weight-loss drugs can be tough to get these days.They’re in short supply, and often too expensive to afford without insurance coverage.Because of these barriers, many people are doing an end-run around t

MedScape 18 September at 09.00 AM

Major Ethnic Differences Seen in Early-Onset Type 2 Diabetes

White Europeans and Black Ugandans who develop type 2 diabetes younger than 40 years differ by gender, body mass index, and beta-cell function.

MedScape 18 September at 07.11 AM

Guidance Will Aid Pediatric to Adult Diabetes Care Transfer

Despite insufficient data, writing panel will give recommendations for preparation, transfer, and follow-up for youth with diabetes transitioning from pediatric to adult endocrine care.

HealthDay 17 September at 03.17 PM

Personality Tied to Cardiovascular Disease Risk With Type 2 Diabetes

Personality traits can influence cardiovascular disease (CVD) risk with type 2 diabetes mellitus (T2DM), according to a study published online Sept. 10 in&nbsp;BMJ Open Diabetes Research &amp; Care.Chan Soon Park, from Seoul National University Hospital in South Korea, and colleagues used data from 8,794 patients with T2DM participati

HealthDay 17 September at 02.58 PM

GLP-1 RA Use Linked to Reduced Cirrhosis Risk in MASLD, Diabetes

For patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a reduced risk for cirrhosis and for cirrhosis complications and mortality, according to a study published online Sept. 16 in JAMA Internal Medicine.Fasiha Kanwal,

MedScape 17 September at 02.21 PM

US Senator Sanders Says Generic Drugmakers Could Sell Ozempic for Less Than $100/month

U.S. Senator Bernie Sanders said on Tuesday he received confirmation from major generic pharmaceutical companies that they could sell copycat versions of Novo Nordisk's...

MedScape 17 September at 09.00 AM

Do Insulin Users Know When Their Blood Sugar Is Low?

A study using blinded continuous glucose monitoring revealed high rates of both asymptomatic and mis-identified hypoglycaemia.

MedScape 17 September at 07.31 AM

Short Steroid Treatment May Raise Diabetes Risk: Study

A large study of UK health records shows patients receiving systemic glucocorticoids during short hospital stays appeared twice as likely to develop new onset diabetes than those who did not.

HealthDay 16 September at 10.26 PM

Gestational Hypertension Tied to Higher Later Risk for Cardiovascular Disease

A self-reported history of gestational hypertension is associated with cardiovascular disease (CVD) in postmenopausal women, according to a study presented at the annual meeting of the Menopause Society, held from Sept. 10 to 14 in Chicago.&nbsp;&nbsp;Marie Tan, from the Drexel University College of Medicine in Philadelphia, and colleagues surv

HealthDay 16 September at 03.56 PM

Social Determinants of Health Affect Monitoring for Diabetic Retinopathy

Certain social determinants of health (SDOH) affect monitoring for diabetic retinopathy (DR), according to a study published online Sept. 12 in JAMA Ophthalmology.Azraa S. Chaudhury, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues examined the association between multiple SDOH and monitorin

MedScape 16 September at 05.25 AM

Will New Obesity Drugs Make Bariatric Surgery Obsolete?

One expert argues "yes," the other, "no." Which will prevail?

HealthDay 13 September at 03.39 PM

Weight Reduction Varies for Patients Receiving Semaglutide, Liraglutide

For patients with obesity receiving semaglutide or liraglutide, weight reduction at one year is associated with medication active agent, dosage, treatment indication, and persistence of coverage, according to a study published online Sept. 13 in JAMA Network Open.Hamlet Gasoyan, Ph.D., from the Cleveland Clinic in Ohio, and colleagues

HealthDay 13 September at 03.35 PM

Once-Weekly Efsitora Noninferior to Degludec for Type 2 Diabetes

Once-weekly efsitora is noninferior to once-daily degludec for reducing glycated hemoglobin levels in adults with type 2 diabetes who have not received insulin, according to a study published online Sept. 10 in the New England Journal of Medicine to coincide with the annual meeting of the European Association for the Study of Diabetes, held f

HealthDay 13 September at 03.03 PM

Time-Restricted Eating Helps to Improve Diabetes Outcomes

Time-restricted eating (TRE) may improve diabetes outcomes, independent of energy intake, according to a study presented at the annual meeting of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.K.A. Bowden Davies, from Manchester Metropolitan University in the United Kingdom, and colleagues examined the eff

MedScape 13 September at 09.17 AM

Semaglutide Reduces MACE, Death in Impaired Kidney Function

A SELECT trial subanalysis showed that semaglutide works as well in people with CVD, overweight/obesity, and impaired kidney function as it does in those with normal kidney function.

MedScape 13 September at 08.49 AM

Tirzepatide Real-World Safety Profile "Reassuring," So Far

Data from the US FDA's Adverse Event Reporting System on tirzepatide showed adverse events generally consistent with those observed with GLP-1 receptor agonists.

MedScape 13 September at 07.35 AM

Asthma and Type 2 Diabetes Have Bidirectional Relationship

Healthcare providers should adopt preventive measures for both asthma and type 2 diabetes in patients diagnosed with either condition, suggested a meta-analysis of 17 million individuals.

MedScape 13 September at 07.24 AM

SGLT-2 Inhibitors Reduce Dementia Risk vs DPP-4 Inhibitors

In patients older than 40 years, the type 2 diabetes drug class showed increased benefits over DPP-4 inhibitors at reducing the risk for dementia and Alzheimer's disease.

MedScape 13 September at 06.50 AM

At Least 20% of US Adults Living With Obesity in Every State

In 23 states, more than one in three (35%) have obesity.

MedScape 13 September at 04.26 AM

SGLT2 Inhibitor Reduces Risk for Dementia, Alzheimer's in T2D

Patients with type 2 diabetes treated with SGLT2is showed significant reductions in the risk for Alzheimer's disease, vascular dementia, and other neurodegenerative conditions.

HealthDay 12 September at 09.22 PM

At Least One in Five People Has Obesity in Each U.S. State

Statistics from 2023 on U.S. obesity rates reveal that in every U.S. state, one in every five people now has obesity, according to&nbsp;data&nbsp;released Thursday by the U.S. Centers for Disease Control and Prevention.In 2013, not one state had an adult obesity rate topping 35 percent, but 10 years later, 23 states had achieved that distinct

HealthDay 12 September at 04.14 PM

Liraglutide Efficacious, Safe for Children Aged 6 to <12 Years

Liraglutide plus lifestyle intervention is efficacious for children aged 6 to &lt;12 years with obesity, according to a study published online Sept. 10 in the New England Journal of Medicine to coincide with the European Association for the Study of Diabetes Congress, held Sept. 9 to 13 in Madrid.Claudia K. Fox, M.D., from the Univer

MedScape 12 September at 12.28 PM

'Remarkable' Weight Loss With Novel Oral Combo in Phase 1

Amycretin, a dual pathway, oral weight loss drug, was found to be safe and tolerable in a phase 1 study and led to weight loss of up to 13% in people with overweight and obesity.

MedScape 12 September at 09.34 AM

Eating Fruits and Oats Ups Type 1 Diabetes Risk in Some Kids

A higher consumption of fruits, oats, or rye upped the risk for T1D in children with genetic susceptibility, while berries such as strawberries and blueberries lowered the risk.

MedScape 12 September at 09.34 AM

Eating Fruits and Oats Ups Type 1 Diabetes Risk in Kids

A higher consumption of fruits, oats, or rye upped the risk for T1D in children with genetic susceptibility, while berries such as strawberries and blueberries lowered the risk.

MedScape 12 September at 09.24 AM

Icodec + Semaglutide Combo Shows Benefit in Type 2 Diabetes

Combination may offer a substitute to basal-bolus insulin in people with type 2 diabetes inadequately controlled with daily basal insulin.

MedScape 12 September at 09.16 AM

Early vs Late Fast Window: Is One More Effective?

Restricting eating to an 8-hour window improves blood glucose no matter whether the eating window is early or late in the day in people at risk for type 2 diabetes.

MedScape 12 September at 05.42 AM

Diabetic Complications Increase Risk for Periodontitis

The coexistence of neuropathy and retinopathy increased the risk for moderate/severe periodontitis, and dyslipidemia had an additive effect.

HealthDay 11 September at 10.21 PM

Risk for T2D Increased for Individuals With Late Chronotype

People with a late chronotype have an increased risk for type 2 diabetes (T2D) and have higher body mass index (BMI) and larger waist circumference, according to a study presented at the annual meeting of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.Jeroen H.P. van der Velde, Ph.D., from Leiden Univer

HealthDay 11 September at 10.16 PM

Exposure to Glucocorticoids Increases Risk for New-Onset Diabetes

Exposure to systemic glucocorticoids during hospitalization is associated with an increased risk for new-onset diabetes, according to a study presented at the annual of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.Rajna Golubic, M.D., Ph.D., from the University of Oxford in the United Kingdom, and col

HealthDay 11 September at 03.27 PM

Hormone Tx Tied to Reductions in Insulin Resistance

Hormone therapy (HT) is associated with significantly reduced insulin resistance in healthy postmenopausal women, according to a study presented at the annual meeting of the Menopause Society, held from Sept. 10 to 14 in Chicago.Tanya Li, from Reading Hospital Tower Health in West Reading, Pennsylvania, and colleagues conducted a systematic

HealthDay 11 September at 03.20 PM

Reciprocal Relationship Identified Between T2D, Asthma

There is a reciprocal relationship between asthma and type 2 diabetes (T2D), according to a study presented at the annual meeting of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.Nam Nhat Nguyen, M.D., from Taipei Medical University in Taiwan, and colleagues conducted a systematic review and meta-analy

MedScape 11 September at 11.53 AM

Liraglutide Reduces BMI by Almost 6% in Children Aged 6 to 12

Liraglutide is the first GLP-1 agonist to show benefit in this age group and could provide young patients a much-needed option.

MedScape 11 September at 09.41 AM

Abdominal Fat Linked to Chronic Pain

The study suggested that excessive abdominal adipose tissue may be involved in the pathogenesis of multisite and widespread chronic musculoskeletal pain.

MedScape 11 September at 07.34 AM

Once-Weekly Insulin Looks Good in T2D, but Risk Seen in T1D

Eli Lilly's efsitora alfa was noninferior to once-daily insulin in type 2 diabetes, but an increased hypoglycemia risk was seen in type 1 diabetes.

MedScape 11 September at 07.25 AM

A Simple Blood Test May Predict Cancer Risk in T2D

Elevated IL-6 levels were linked to an increased risk for obesity-related cancers in patients with newly diagnosed type 2 diabetes, a Danish study showed.

MedScape 11 September at 06.42 AM

AI Voice Analysis for Diabetes Screening Shows Promise

The artificial intelligence algorithm based on voice analysis showed "excellent agreement" with the American Diabetes Association type 2 diabetes risk test.

HealthDay 10 September at 03.54 PM

Certain Foods May Increase Risk for Developing Type 1 Diabetes in At-Risk Children

Higher consumption of oats, gluten-containing cereals, and fruits by young children is associated with an increased risk for several type 1 diabetes measures, according to a study presented at the annual meeting of the European Association for the Study of Diabetes, held Sept. 9 to 13 in Madrid.Suvi M. Virtanen, from the Finnish Institute for

HealthDay 10 September at 03.50 PM

Diabetes, Prediabetes Tied to Accelerated Brain Aging

Diabetes and prediabetes are associated with accelerated brain aging and potential dementia, according to a study published online Aug. 28 in&nbsp;Diabetes Care.Abigail Dove, from the Karolinska Institutet in Stockholm, and colleagues investigated the association between (pre)diabetes and older brain age. The analysis included 31,229

MedScape 10 September at 12.47 PM

Finerenone Reduces T2D Onset in HF With Preserved EF

In addition to improving heart failure symptoms, finerenone reduced the onset of new type 2 diabetes in patients with mildly reduced or preserved ejection fraction.

MedScape 10 September at 11.09 AM

Do SGLT2 Inhibitors Benefit Everyone With T2D and CKD?

New data suggest that current recommendations overstate the proportion of patients who would receive significant kidney protection.

MedScape 10 September at 06.39 AM

Night Owls May Be at Greater Risk for T2D, Beyond Lifestyle

The circadian rhythm of individuals with late chronotypes may be out of sync with social schedules, setting the stage for metabolic disturbances and type 2 diabetes.

MedScape 09 September at 06.00 PM

Abnormal HR Shifts Tied to Risk for Death in Diabetes

A reduction in 24-hour heart rate variations was linked to twice the risk for long-term cardiovascular death, while the inability to reduce heart rate during sleep was linked to 39% increased risk.

HealthDay 09 September at 04.05 PM

Insulin Resistance Linked to Risk for More Than 30 Diseases

Insulin resistance (IR) is associated with multiple systemic diseases, according a study presented at the annual meeting of the European Association for the Study of Diabetes, held from Sept. 9 to 13 in Madrid.Jing Wu and Y. Song, from the Cheeloo College of Medicine at Shandong University in Jinan, China, explored the correlation between IR and

HealthDay 09 September at 03.49 PM

Hypertension Prevalence 22.7 Percent Among Young Adults

The prevalence of hypertension is 22.7 percent among young adults aged 18 to 39 years and 5.4 percent among youth aged 8 to 19 years, according to two studies presented at the American Heart Association Hypertension 2024 Scientific Sessions, held from Sept. 5 to 8 in Chicago.Thomas J. Alexander, from the Northwestern University Feinberg School o

HealthDay 09 September at 03.42 PM

Specific PFAS Differentially Affect Maternal Midlife Adiposity

Specific perfluoroalkyl and polyfluoroalkyl substances (PFAS) measured in early pregnancy differentially affect maternal midlife adiposity, according to a study published online Sept. 5 in the Journal of Clinical Endocrinology &amp; Metabolism.Jordan A. Burdeau, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and co

HealthDay 09 September at 03.33 PM

Skin Care Product Use by Children Tied to Phthalates/Replacement Metabolites

In young children, skin care product (SCP) use is associated with urinary phthalate/replacement metabolites, according to a study published online Sept. 4 in Environmental Health Perspectives.Michael S. Bloom, Ph.D., from George Mason University in Fairfax, Virginia, and colleagues examined the associations between SCP use and children'

MedScape 09 September at 10.10 AM

Diet May Affect Gut Hormones Less Than Drugs, Surgery

An analysis of short-term dietary changes indicated that it resulted in less changes in gut-derived appetite hormones than found in studies of pharmaceutical and surgical interventions.

MedScape 09 September at 07.47 AM

US FDA Lifts Partial Clinical Hold on Rezolute's Low Blood Sugar Treatment

Rezolute Inc said on Monday the U.S. Food and Drug Administration had lifted its partial clinical hold on a late-stage study testing the company's treatment for low blood...

MedScape 09 September at 07.33 AM

Terns' Oral Weight-loss Drug Shows Promise in Early Study, Shares Jump

Terns Pharmaceuticals said its oral obesity drug reduced weight by an average of 4.9% in an early stage study, joining drugmakers vying for a share of the lucrative obesity...

MedScape 09 September at 07.32 AM

Will Tirzepatide Vials Help Patients? Endos Weigh in

The new discounted single-dose formulation will likely improve access to low doses of the weight loss drug for certain patients but may not help those needing higher doses, said endocrinologists.

MedScape 09 September at 03.26 AM

Monthly Semaglutide Goal: The End of Daily Pills?

An injectable hydrogel provided a sustained release of semaglutide for 1 month in rats, according to preclinical testing of an experimental longer-acting formulation.

HealthDay 06 September at 04.00 PM

Noise, Air Pollution May Impact Fertility

Air pollution is associated with a higher risk for an infertility diagnosis in men, while road traffic noise pollution is associated with a higher risk for an infertility diagnosis in women aged 35 years and older, according to a study published online Sept. 4 in&nbsp;The BMJ.Mette Sørensen, Ph.D., from the Danish Cancer Institute in Co

MedScape 06 September at 07.24 AM

A New Focus for Cushing Syndrome Screening in Obesity

Screening for Cushing syndrome in patients with obesity revealed a low prevalence, with nearly all the risk for the rare endocrine disorder in the metabolically unhealthy obesity phenotype.

MedScape 06 September at 04.39 AM

Health Rounds: Next Generation Lilly Weight-loss Drug Shows Added Heart, Liver Benefits

Eli Lilly's experimental next generation weight-loss drug mimics three hormones instead of just one or two and continues to show promising clinical trial results for...

MedScape 06 September at 03.37 AM

How 'Oatzempic' Stacks up to Ozempic

In people with diabetes, the "oatzempic" online diet fad may lead to increased glucose, decreased muscle mass, and malnutrition.

HealthDay 05 September at 10.28 PM

Interactive Map Highlights PAD Amputation Hotspots in the U.S.

A new interactive map has been created by the American Heart Association (AHA) to illustrate the risk for leg, foot, or toe amputations due to peripheral artery disease (PAD) in different regions of the United States.Mississippi has the highest risk for lower limb amputation, followed by Texas, Louisiana, Alabama, and South Carolina, the <a hr

HealthDay 05 September at 03.06 PM

Report Reveals Extent of Cost-Related Medication Nonadherence in Seniors

About 3.5 percent of older adults do not take prescription medications due to cost and a similar percentage do not take medications as prescribed due to cost, according to a study published online Sept. 5 in the&nbsp;National Health Statistics Reports, a publication from the National Center for Health Statistics.Robin A. Cohen, Ph.D.,

MedScape 05 September at 05.06 AM

How Fake Ozempic Batch Numbers Help Criminal Groups Spread Dangerous Drugs

In December, Drew, a 36-year-old man from San Antonio, Texas, drove more than 250 miles (400 km) to Mexico to buy cheap Ozempic to help him lose weight. Going home, he...

MedScape 05 September at 05.02 AM

Factbox-How to Find and Check an Ozempic Batch Number

Explosive demand and high prices for Novo Nordisk and Eli Lilly's weight loss and diabetes drugs have fueled a criminal effort to package autoinjector pens containing other...

HealthDay 04 September at 02.52 PM

High Insulin Levels Genetically Linked to Lower Lipoprotein(a)

There is an association between genetically predicted increased insulin concentrations and decreased concentrations of circulating lipoprotein(a) (Lp[a]), according to a study published online Aug. 29 in&nbsp;Cardiovascular Diabetology&nbsp;to coincide with the European Society of Cardiology Congress 2024, held from Aug. 30 to Sept. 2 in Lo

MedScape 04 September at 03.22 AM

Ozempic Shortages in EU Will Not Affect All Member States - Novo Nordisk

Intermittent shortages of diabetes drug Ozempic in the European Union that are expected to continue into the final quarter of 2024 because of strong demand will not affect...

HealthDay 03 September at 08.11 PM

Semaglutide Does Not Increase Psychiatric Complications in Overweight, Obesity

Treatment with semaglutide does not increase the risk for developing symptoms of depression or suicidal ideation/behavior among adults with overweight or obesity, according to a study published online Sept. 3 in JAMA Internal Medicine.Thomas A. Wadden, Ph.D., from the Perelman School of Medicine at the University of Pennsylvania in Phi

HealthDay 03 September at 08.11 PM

SGLT-2 Inhibitors May Cut Dementia Risk in Patients With Diabetes

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors may prevent dementia in middle-aged adults with diabetes, according to a study published online Aug. 28 in&nbsp;The BMJ.Anna Shin, from Seoul National University Bundang Hospital in South Korea, and colleagues compared the risk for dementia associated with SGLT-2 inhibitors versus dipe

HealthDay 03 September at 04.09 PM

Interleukin-6 May Boost Prediction of Obesity-Related Cancers

In patients with newly diagnosed type 2 diabetes, baseline interleukin-6 (IL-6) levels may enhance prediction of new-onset obesity-related cancers, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.Mathilde Dahlin Bennetsen, from th

MedScape 03 September at 04.41 AM

Eat a Plant-Based Diet to Lower Diabetes Risk

A new paper based on self-reported diet information from major studies and analysis of biomarkers added to the evidence about risks for meat consumption.

MedScape 30 August at 09.54 AM

Drugs, Complications, and Collaborations All on EASD Agenda

The upcoming EASD meeting will feature new data on once-weekly insulin and GLP-1 drugs and joint society collaborations addressing diabetes complications.

MedScape 30 August at 05.43 AM

Intermittent Fasting Aids Patients With Prediabetes or T2D

The approach is associated with reductions in body weight, BMI, and A1c levels.

MedScape 30 August at 03.42 AM

How Do Plant-based Foods Reduce Type 2 Diabetes Risk?

A higher intake of lignans, found in seeds, whole grains, and coffee and tea, was associated with a decreased risk of developing type 2 diabetes.

MedScape 29 August at 04.25 AM

Men, Women, & Exercise: Metabolism Differs at Starting Line

The muscles of sedentary men and women with overweight and obesity differ in burning sugar and fatty acids at the start of an exercise program but draw even after training, multi-omics data show.

HealthDay 28 August at 09.56 PM

Chronic Diabetes Complications Bidirectionally Linked to Mental Health Disorders

There is a consistent, bidirectional association between chronic diabetes complications (CDCs) and mental health disorders (MHDs), according to a study published online July 15 in&nbsp;Diabetes Care.Maya Watanabe, from the University of Michigan in Ann Arbor, and colleagues examined bidirectional associations between the timing of CD

MedScape 28 August at 01.22 PM

NICE: Give People With Adrenal Insufficiency Emergency Kits

People with adrenal insufficiency should be given emergency kits to help avoid hospital admission, said NICE in its new clinical guideline.

MedScape 28 August at 09.00 AM

Continuous Glucose Monitor Benefits All Ages With Diabetes

Intermittently scanned continuous glucose monitoring improved glycaemic outcomes in those older and younger than 65 years, but the older group may need individualised targets.

HealthDay 27 August at 09.50 PM

Team-Based Documentation Can Increase Visit Volume, Cut Documentation Time

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

HealthDay 27 August at 09.47 PM

FDA Expands Approval of Omnipod 5 Insulin Delivery System to Include Patients With Type 2 Diabetes

On Monday, the U.S. Food and Drug Administration approved the Insulet Omnipod 5 insulin delivery system for patients with type 2 diabetes. It is the first such system for use by people with the more prevalent form of the disease.The FDA first signed off on the system, which automatically adjusts insulin delivery as needed, for type 1 diabetes i

HealthDay 27 August at 04.09 PM

Meat Consumption Linked to Increased Incidence of Type 2 Diabetes

Consumption of unprocessed red meat, processed meat, and poultry is associated with an increased incidence of type 2 diabetes, according to a study published online in the September issue of The Lancet Diabetes &amp; Endocrinology.Chunxiao Li, Ph.D., from the University of Cambridge School of Clinical Medicine in the United Kingdom, an

HealthDay 27 August at 02.12 PM

Weight-Loss Drug Zepbound Now in Single-Dose Vials at Half the Price

Eli Lilly, maker of one of the blockbuster GLP-1 weight-loss drug Zepbound, says it will now offer the medication in single-dose vials at half the price currently available to consumers.The new 2.5 milligram (mg) and 5 mg weekly dose vials differ from the standard preloaded injector pens that are used to administer Zepbound (tirzepatide) and co

MedScape 27 August at 09.41 AM

Semaglutide Coverage Could Raise Medicare Costs by Billions

Medicare's expanded coverage for semaglutide meant that around one in seven Medicare beneficiaries with a high BMI would be newly eligible for semaglutide treatment.

MedScape 27 August at 06.59 AM

Thyroid Surgery Increases Kidney Disease Risk

Patients who underwent total thyroidectomy had an increased risk for chronic kidney disease, particularly those who developed hypoparathyroidism.

MedScape 27 August at 06.49 AM

Lilly Launches Vials Of Weight-loss Drug Zepbound for as Low as $399 a Month

Eli Lilly said on Tuesday it has begun selling vials of the lowest starter dose of its popular weight-loss drug Zepbound in the United States for $399 for a month's supply...

MedScape 27 August at 06.49 AM

Lilly Launches Smallest Single-dose Vials Of Zepbound for $399

Eli Lilly said it has begun selling vials of the smallest, starter dose of its popular weight-loss drug Zepbound in the United States for $399 for a month on its...

HealthDay 26 August at 09.45 PM

Risk for Dementia Similar With SGLT2 Inhibitors, Dulaglutide in T2DM

For older adults with type 2 diabetes, the risk for dementia seems similar with sodium-glucose cotransporter 2 (SGLT2) inhibitors and the glucagon-like peptide 1 receptor agonist (GLP-1 RA) dulaglutide, according to a study published online Aug. 27 in the Annals of Internal Medicine.Bin Hong, from the School of Pharmacy at Sungkyunkwan

MedScape 26 August at 05.19 PM

FDA Clears the Omnipod 5 System for Type 2 Diabetes

New indication represents the first for use of an automated insulin delivery system in people with type 2 diabetes who require insulin treatment.

MedScape 26 August at 09.00 AM

First Over-the-Counter Continuous Glucose Monitor Launches

Dexcom's Stelo, designed for people older than 18 years with diabetes or prediabetes not on insulin or not at a risk for hypoglycemia, will be available without a prescription.

MedScape 26 August at 08.44 AM

Lobectomy Doesn't Raise Reoperation Rates in Thyroid Cancer

Despite a shift toward performing more initial lobectomies for thyroid cancer following the release of the 2015 ATA guidelines, the rate of late reoperations remained unchanged.

HealthDay 23 August at 10.39 PM

Type 2 Diabetes Prevalence Rose in the United States From 2012 to 2022

The prevalence of diabetes increased in the United States from 2012 to 2022, according to a research letter published online July 18 in&nbsp;Diabetes, Obesity and Metabolism.Sulakshan Neupane, from the University of Georgia in Athens, and colleagues examined recent national trends and disparities in self-reported diabetes prevalence amo

HealthDay 23 August at 10.37 PM

Exposure to Tobacco on TV, Streaming Varies by Sociodemographics

Exposure to tobacco on television or streaming platforms differs by key sociodemographic and behavioral characteristics, according to a study published online Aug. 22 in&nbsp;JAMA Network Open.Henry K. Onyeaka, M.D., from Harvard Medical School in Boston, and colleagues examined the prevalence and factors associated with exposure to tob

HealthDay 23 August at 03.54 PM

Inflammation in Childhood Linked to Onset of Mental Health Disorders

Low-grade systemic inflammation across childhood and adolescence is associated with the subsequent onset of mental health disorders, according to a study published online Aug. 21 in JAMA Psychiatry.Edward R. Palmer, M.B.B.S., from the University of Birmingham in the United Kingdom, and colleagues examined trajectories of inflammation, a

MedScape 23 August at 06.18 AM

Steps to Take for Diagnosing Cushing Syndrome

Your patient's "round face" might be the first clue that he or she has Cushing syndrome, but there are other symptoms as well. How can you accurately diagnose the condition?

MedScape 23 August at 02.58 AM

PCOS Linked to Higher Risk for Cardiometabolic Diseases

Women with polycystic ovary syndrome showed an increased risk for cardiometabolic diseases, with the risk varying according to phenotype.

HealthDay 22 August at 10.05 PM

Study Reveals Heart Failure Risks in American Indian Communities

A study published online Aug. 21 in the Journal of the American Heart Association reveals the major contributors to heart failure risk in American Indians, highlighting the roles of age, smoking, and diabetes.Irene Martinez-Morata, M.D., M.P.H., from the Columbia University Mailman School of Public Health in New York City, and colleag

HealthDay 22 August at 09.33 AM

Americans Have Mixed Feelings About AI in Health Care, Poll Finds

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

MedScape 22 August at 01.29 AM

SGLT2 vs DPP4 Inhibitor: Which Protects Liver Better in T2D?

SGLT2 inhibitors did not reduce the risk for adverse liver outcomes more than DPP-4 inhibitors in patients with type 2 diabetes and metabolic dysfunction–associated steatotic liver disease.

HealthDay 21 August at 03.42 PM

Study Looks at Impact of Hypothyroidism, Hypothyroxinemia in Pregnancy

For women with subclinical hypothyroidism (SH) or hypothyroxinemia (HT) diagnosed during the first half of pregnancy, SH is associated with higher rates of overt hypothyroidism or thyroid replacement therapy within five years of delivery, according to a study published online July 31 in Thyroid.Michael W. Varner, M.D., from the Unive

HealthDay 21 August at 03.31 PM

2020 to 2021 Saw Decline in Life Expectancy for 39 States, Increase for 11

From 2020 to 2021, life expectancy at birth declined for 39 U.S. states and increased for 11 states, according to the Aug. 21 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Elizabeth Arias, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues p

HealthDay 21 August at 03.20 PM

Semaglutide-Linked Suicidal Ideation ID'd in Disproportionality Analysis

Semaglutide-associated suicidal ideation has been identified in a disproportionality analysis, according to a study published online Aug. 20 in JAMA Network Open.Georgios Schoretsanitis, M.D., Ph.D., from Northwell Health in Glen Oaks, New York, and colleagues examined potential signals for suicidal and self-injurious adverse drug re

MedScape 21 August at 07.33 AM

Will Compounding 'Best Practices' Guide Reassure Clinicians?

The new guide aimed to educate compounding pharmacists and reassure prescribers about the ethical, legal, and practical considerations that must be addressed to ensure quality standards.

MedScape 21 August at 05.07 AM

Tirzepatide Reduces Progression From Prediabetes to T2D

Topline data from Lilly's SURMOUNT 1 trial shows a 94% reduction in the development of type 2 diabetes among those with prediabetes and overweight/obesity.

HealthDay 20 August at 03.50 PM

More Than Half of Older Adults Very Concerned About Medical Costs

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

MedScape 20 August at 09.06 AM

Gender and Sports: Can Science Enable Fair Competition?

The allegations against Algerian boxer Imane Khelif raised the complicated question of intersexuality and its implications for competitive sports.

MedScape 20 August at 08.39 AM

Repurposed CT Scan Data Can Reveal Hidden Diabetes Risks

Automated analysis of past CT scans predicted current and future risks for type 2 diabetes better than traditional measures, found a large retrospective study.

MedScape 20 August at 04.55 AM

More Clinical Benefits With Tirzepatide vs GLP-1 RA in T2D

A large retrospective study of electronic medical records found better cardiovascular and renal outcomes in patients with type 2 diabetes treated with tirzepatide vs GLP-1 RAs.

HealthDay 19 August at 10.00 PM

Low Nurse Staffing Tied to Higher Risk for Patient Death

The risk for patient death associated with low nurse staffing is only partly alleviated by using temporary staff to fill shortfalls, according to a study published online Aug. 19 in&nbsp;JAMA Network Open.Peter Griffiths, R.N., Ph.D., from the University of Southampton in the United Kingdom, and colleagues explored the association betwe

HealthDay 19 August at 03.30 PM

Heme Iron Intake Linked to Increased Risk for Type 2 Diabetes

Heme iron intake is associated with an increased risk for type 2 diabetes (T2D), according to a study published online Aug. 13 in Nature Medicine.Fenglei Wang, Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues analyzed data from 204,615 participants in large U.S. cohorts during up to 36 years to examine

HealthDay 16 August at 09.24 PM

Automated Multiorgan CT Can Predict Diabetes, Other Conditions

Automated multiorgan computed tomography (CT), including visceral fat, can predict diabetes and associated cardiometabolic conditions, according to a study published online Aug. 6 in Radiology.Yoosoo Chang, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues examined the ability of automate

HealthDay 16 August at 02.36 PM

Risk for Developing Type 1 Diabetes Doubled With Paternal Link

Individuals are less likely to have type 1 diabetes if their mother has the condition than if their father is affected, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.Lowri A. Allen, M.B.Ch.B., from Cardiff University in the Unite

MedScape 16 August at 07.55 AM

New Data Shed Light on Type 1 Diabetes Male Predominance

Gender prevalence is equal in young children, but trajectory appears to diverge around puberty.

MedScape 16 August at 07.03 AM

GLP-1 RAs Reduce Hyperkalemia Risk, Prolong RASi Use

Two classes of newer medications for glycemic control in type 2 diabetes differed in hyperkalemia risk and discontinuation of renin-angiotensin system inhibitors, a large cohort study found.

MedScape 16 August at 03.46 AM

Medtronic Revamps Its Continuous Glucose Monitor Platform

The company will launch two new sensors that are compatible with its insulin pump and smart insulin pen products and will also partner with Abbott Diabetes Care for a bespoke sensor.

MedScape 16 August at 01.42 AM

What Every Provider Needs to Know About Type 1 Diabetes

A freelance journalist shares tips based on her experience living with type 1 diabetes, including how it differs from type 2 in ways that may be underappreciated in nonspecialist settings.

HealthDay 15 August at 09.57 PM

FDA Starts Phase II of Efforts to Reduce Salt Levels in Food

The U.S. Food and Drug Administration on Thursday announced Phase II of its initial efforts to cut dietary salt intake by Americans.U.S. Dietary Guidelines recommend that a person consume no

HealthDay 15 August at 03.51 PM

Improving PTSD May Also Improve Diabetes Outcomes

No longer meeting diagnostic criteria for posttraumatic stress disorder (PTSD) is associated with a lower risk for poor diabetes outcomes, particularly among younger veterans, according to a study published online Aug. 13 in&nbsp;JAMA Network Open.Jeffrey F. Scherrer, Ph.D., from the Saint Louis University School of Medicine, and coll

HealthDay 15 August at 03.47 PM

Low-Cost, Group-Based Lifestyle Intervention Aids Diabetes Outcomes

Even individuals with a high genetic risk for type 2 diabetes (T2D) benefit from a low-cost, group-based intervention focused on healthy diet and physical activity, according to a study recently published online in the&nbsp;Journal of Clinical Endocrinology &amp; Metabolism.Maria Anneli Lankinen, Ph.D., from the University of Eastern

MedScape 15 August at 12.46 PM

T2D Fracture Risk Likely Due to Impaired Physical Function

Poorer physical function, not poorer bone mineral density (BMD), could be the principal reason for the increased fracture risk in older women with type 2 diabetes (T2D).

MedScape 15 August at 12.00 PM

T1D: Bone Health May Falter Before Nerves in Adolescence

The onset of diabetic neuropathy was not necessary for the deterioration of bones in adolescent girls with T1D.

HealthDay 15 August at 11.36 AM

New Deals Will Cut Medicare Costs for Expensive Drugs

The Biden administration said Thursday that it has signed deals with drug companies that will lower the prices on 10 of the most popular and expensive drugs used by American seniors.Taxpayers should save $6 billion because of the new prices, while seniors using Medicare could save roughly $1.5 billion on their medications, the U.S. Centers for

MedScape 15 August at 06.53 AM

'New Era' in Insulin Possible if Research Successful

Six global research projects have been granted £15 million to develop novel insulin analogs that work better than current products.

MedScape 15 August at 05.00 AM

Monitor Antiobesity Drug Dosing After Rapid Weight Loss

In a 'teachable moment' case, a patient who did not have their levothyroxine dose adjusted after rapid weight loss with tirzepatide wound up in the emergency department.

HealthDay 14 August at 03.53 PM

Past-Month Cannabis Use Increasing Among Adults With Diabetes

Among U.S. adults with diabetes, cannabis use in the past month increased by 33.7 percent from 2021 to 2022, according to a research letter published online July 22 in Diabetes Care.Benjamin H. Han, M.D., M.P.H., from the University of California, San Diego, School of Medicine in La Jolla, and colleagues estimated the most recent nat

HealthDay 14 August at 03.45 PM

Clinicians Are Interested in Climate Change Education

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

MedScape 14 August at 11.14 AM

Lilly Demands Doctors Stop Selling Copycat Weight-loss Drugs

Eli Lilly has sent cease-and-desist letters to U.S. healthcare providers in recent days to stop the promotion of the compounded versions of its drugs for weight loss and...

MedScape 14 August at 10.52 AM

Can Dry Fasting Help With Metabolic Disorders, Diabetes?

Despite the social media hype and a few very small studies, dry fasting is unlikely to improve health and may cause harm.

MedScape 14 August at 08.05 AM

Intermittent Fasting Aids Weight Loss in Prediabetes and T2D

Intermittent fasting reduced body weight and BMI and improved glycemic outcomes in adults with prediabetes or T2D.

MedScape 14 August at 04.49 AM

Processed Foods Linked to Diabetic Complications

Consuming more ultraprocessed food was linked to an increased risk for microvascular complications, especially diabetic kidney disease, in a cohort of patients with T2D.

HealthDay 13 August at 03.41 PM

Poor Long-Term Sleep Trajectories Tied to Diabetes

Adults with suboptimal sleep duration trajectories are more likely to develop incident diabetes, according to a study published online June 27 in&nbsp;Diabetologia.Qian Xiao, Ph.D., M.P.H., from the University of Texas Health Science Center at Houston, and colleagues assessed long-term trajectories of sleep duration and incident diabet

HealthDay 13 August at 03.36 PM

PCOS Linked to Increased Odds of Eating Disorders

Polycystic ovary syndrome (PCOS) is associated with an increased likelihood of any eating disorder, according to a review published online Aug. 8 in the Journal of Clinical Endocrinology &amp; Metabolism.Laura G. Cooney, M.D., from the University of Wisconsin in Madison, and colleagues conducted a systematic review and meta-analysis to

HealthDay 12 August at 09.50 PM

GLP-1 RA Use Linked to Lower Rates of Hyperkalemia in Type 2 Diabetes

Treatment with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is associated with lower rates of hyperkalemia and a lower rate of renin-angiotensin system inhibitor (RASi) discontinuation compared with treatment with dipeptidyl peptidase-4 inhibitors (DPP-4is) among patients with type 2 diabetes (T2D), according to a study published online Aug. 1

HealthDay 12 August at 04.11 PM

Risks for Mortality, Adverse Heart, Kidney Events Lower With Tirzepatide for T2DM

For patients with type 2 diabetes, treatment with tirzepatide (a dual glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide receptor agonist) is associated with lower risks for all-cause mortality and adverse cardiovascular and kidney events compared with glucagon-like peptide 1 receptor agonist treatment (GLP-1 RA), according to a s

HealthDay 09 August at 08.15 PM

Neighborhood Socioeconomic Status Linked to Premature Mortality

Low neighborhood socioeconomic status (SES) is associated with premature mortality, according to a study published online Aug. 8 in JAMA Network Open.Wayne R. Lawrence, Dr.P.H., from the National Institutes of Health in Rockville, Maryland, and colleagues examined the association of life-course neighborhood SES and premature mortality in

HealthDay 09 August at 08.10 PM

1990 to 2018 Saw Global Rise in Sugar-Sweetened Beverage Consumption by Youth

Intake of sugar-sweetened beverages (SSBs) among children and adolescents increased by 23 percent globally from 1990 to 2018, according to a study published online Aug. 7 in&nbsp;The BMJ.Laura Lara-Castor, Ph.D., from the Friedman School of Nutrition Science and Policy at Tufts University in Boston, and colleagues quantified global intak

HealthDay 09 August at 03.57 PM

Remission of Type 2 Diabetes Feasible With Soup and Shake Diet Intervention

A behavioral intervention designed to support weight loss can yield remission of type 2 diabetes, according to a study published online Aug. 5 in The Lancet Diabetes &amp; Endocrinology.Jonathan Valabhji, M.D., from NHS England in the United Kingdom, and colleagues assessed remission of type 2 diabetes among participants in the NHS Type

HealthDay 09 August at 03.49 PM

Fracture Risk Higher in Women With T2DM Due to Poorer Physical Function

Women with type 2 diabetes (T2D) have higher bone mineral density (BMD) and better bone microarchitecture, but poorer physical function than women without diabetes, according to a study published online Aug. 7 in JAMA Network Open.Michail Zoulakis, M.D., from the Sahlgrenska Osteoporosis Centre at the University of Gothenburg in Sweden,

HealthDay 08 August at 11.00 PM

CDC Presents Provisional Mortality Data for 2023 in the United States

In 2023, there was a provisional total of 3,090,582 deaths in the United States, according to research published in the Aug. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Farid B. Ahmad, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues

HealthDay 08 August at 04.14 PM

HbA1c Stability Tied to Lower Risk for Alzheimer Disease and Related Dementias

Increased glycated hemoglobin (HbA1c) stability within patient-specific target ranges is associated with a lower risk for Alzheimer disease and related dementias (ADRD), according to a study published online Aug. 2 in&nbsp;JAMA Network Open.Patricia C. Underwood, Ph.D., from the William F. Connell School of Nursing at Boston College, a

HealthDay 08 August at 03.42 PM

ChatGPT Only Gets Diagnoses Correct Half of the Time

ChatGPT is not accurate as a diagnostic tool, but does offer some medical educational benefits, according to a study published online July 31 in&nbsp;PLOS ONE.Ali Hadi, from the Schulich School of Medicine and Dentistry at Western University in London, Ontario, Canada, and colleagues investigated ChatGPT’s diagnostic accuracy and utili

HealthDay 07 August at 03.13 PM

Short, Long Sleep Duration Tied to Microvascular Disease in Type 2 Diabetes

For individuals newly diagnosed with type 2 diabetes mellitus (T2DM), both short and long sleep duration are associated with microvascular disease, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.Mette S. Johansen, from Odense Un

HealthDay 07 August at 03.10 PM

Complex Interaction Seen Between Social Determinants of Health, Mortality

There is a complex interaction among social determinants of health with mortality risk, but a scoring system is able to identify subgroups with a high risk for mortality, according to a study published online Aug. 5 in BMJ Open.Marie-Pier Bergeron-Boucher, Ph.D., from the Interdisciplinary Centre on Population Dynamics at Syddansk Uni

HealthDay 07 August at 10.47 AM

EPA Bans Vegetable Pesticide That Can Harm Fetuses

In an historic move, the Environmental Protection Agency on Tuesday banned the use of a pesticide that can harm fetuses.Known as dimethyl tetrachloroterephthalate (DCPA or Dacthal), the weedkiller is used on a variety of crops, including broccoli, onions, kale, Brussels sprouts and cabbage.However, when a pregnant woman is exposed to th

HealthDay 06 August at 04.02 PM

Digital Diabetes Prevention Program Cost-Effective for Preventing T2D

For individuals with prediabetes, a digital diabetes prevention program (d-DPP) is cost-effective compared with an in-person lifestyle intervention for preventing development of type 2 diabetes (T2D), according to a study published online July 26 in Diabetes, Obesity and Metabolism.Sooyeol Park, from the Tulane University School of Publ

HealthDay 06 August at 03.50 PM

City-Level Taxes on Sugar-Sweetened Beverages Tied to Lower Youth BMI

City-level excise taxes on sugar-sweetened beverages (SSBs) are associated with lower body mass index (BMI) among youths, according to a study published online July 31 in&nbsp;JAMA Network Open.Deborah Rohm Young, Ph.D., from Kaiser Permanente Southern California in Pasadena, and colleagues examined whether city-level excise taxes on SS

HealthDay 06 August at 03.41 PM

Antibody-Positive Males Face Higher Risk for Type 1 Diabetes Progression

The risk for progression to type 1 diabetes (T1D) is significantly higher in antibody-positive males compared with females, with age differences in risk trajectories, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.Erin L. Templema

HealthDay 05 August at 04.03 PM

2021 to 2023 Saw Considerable Increase in Semaglutide Fills

From 2021 through 2023, there was a considerable increase in the number of semaglutide fills, according to a research letter published online Aug. 2 in JAMA Health Forum.Christopher Scannell, M.D., Ph.D., from the University of Southern California in Los Angeles, and colleagues analyzed trends in prescriptions dispensed at retail pharmac

HealthDay 02 August at 10.57 PM

Long-Term Low-Carb Diet Efficacious for Treating Dyslipidemia in T2D

For individuals with type 2 diabetes, long-term low-carbohydrate diets (LCD) are efficacious for treatment of dyslipidemia but do not affect glycemic control, according to a review published online July 24 in the Journal of Diabetes Investigation.Takahiro Ichikawa, from the Kyoto Prefectural University of Medicine in Japan, and colleague

HealthDay 02 August at 04.03 PM

Semaglutide Products Being Sold Online Without Prescriptions

Semaglutide products are being sold online, with products likely unregistered or unlicensed, according to a research letter published online Aug. 2 in JAMA Network Open.Amir Reza Ashraf, Pharm.D., from the University of Pécs in Hungary, and colleagues conducted a risk assessment of semaglutide online sourcing. Websites advertising semagl

HealthDay 01 August at 04.11 PM

CDC Report Addresses Nonfinancial Access Barriers to Care in 2022

Nonfinancial access barriers to care represent a persistent problem in the United States, with more than 12 percent of adults reporting being too busy to go to a provider, according to a study published online Aug. 1 in the&nbsp;National Health Statistics Reports, a publication from the National Center for Health Statistics.Amanda E. N

HealthDay 31 July at 10.57 PM

58.7 Percent of U.S. Adults Walked for Leisure in Past Week in 2022

In 2022, 58.7 percent of adults walked for leisure in the past seven days and 16.2 percent of adults walked for transportation, according to a July data brief published by the National Center for Health Statistics.Dzifa Adjaye-Gbewonyo, Ph.D., and Elizabeth M. Briones, Ph.D., from the National Center for Health Statistics in Hyattsville, Mary

HealthDay 31 July at 04.04 PM

Common Genetic Risk Seen for Primary Ovarian Insufficiency, Cancer

There seems to be a common genetic risk for primary ovarian insufficiency (POI) and reproductive cancer risk, according to a study published online July 12 in the Journal of Clinical Endocrinology &amp; Metabolism.Kristina Allen-Brady, Ph.D., M.P.H., from the Huntsman Can

HealthDay 31 July at 03.53 PM

Cholesterol Absorption Inhibitors May Cut Risk for Liver Cancer

The use of cholesterol absorption inhibitors is associated with a reduced risk for liver cancer, according to a study published online July 29 in&nbsp;Cancer.Shahriar A. Zamani, Ph.D., from the National Cancer Institute at the National Institutes of Health in Rockville, Maryland, and colleagues examined the risk for liver cancer for

HealthDay 30 July at 08.59 PM

CDC: Despite Wanting to Quit, Only 8.8 Percent Quit Smoking in 2022

Although about two-thirds of U.S. adults who smoked wanted to quit, only 8.8 percent of smokers quit in 2022, according to research published in the July 25 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Brenna VanFrank, M.D., from the CDC in Atlanta, and colleagues used 2022 National

HealthDay 30 July at 09.57 AM

FDA Warns of Accidental Overdoses From Compounded Versions of Ozempic

People taking compounded versions of Ozempic have been overdosing on the drug, the U.S. Food and Drug Administration warns.These ODs typically are due to miscommunications or miscalculations regarding dosage, the FDA added.“Dosing errors have res

HealthDay 29 July at 09.30 PM

Semaglutide Seems Beneficial for Comorbid T2DM, Tobacco Use Disorder

For patients with type 2 diabetes mellitus (T2DM) and tobacco use disorder (TUD), new use of semaglutide is associated with lower risk of TUD-related health care measures compared with other antidiabetes medications, according to a study published online July 30 in the Annals of Internal Medicine.William Wang, from the Case Western Rese

HealthDay 29 July at 03.30 PM

Study Looks at Effects of Reducing Intake of Processed Meat, Unprocessed Red Meat

Reductions in processed meat and unprocessed red meat consumption could result in fewer occurrences of type 2 diabetes, cardiovascular disease, colorectal cancer, and all-cause deaths, according to a study published in the July issue of The Lancet Planetary Health.Joe Kennedy, Ph.D., from the University of Edinburgh in the United Kingdo

HealthDay 26 July at 03.48 PM

GLP1RAs Tied to Greater Risk of Diabetic Retinopathy Progression Than SGLT2is

In patients with diabetes and established diabetic retinopathy (DR), treatment with glucagon-like peptide 1 receptor agonists (GLP1RAs) is associated with increased risks of DR progression compared with sodium-glucose cotransporter 2 inhibitors (SGLT2is), according to a study published online July 19 in&nbsp;Diabetes, Obesity and Metabolism.</

HealthDay 26 July at 10.45 AM

Certain Abbott Blood Sugar Monitors May Give Incorrect Readings

Abbott has warned diabetes patients that some of its continuous blood sugar monitoring systems may need to be replaced because of inaccurate readings."Abbott has recently identified a small number of FreeStyle Libre 3 sensors that may provide incorrect high glucose readings, which if undetected may pose a potential health risk for people living

HealthDay 25 July at 03.33 PM

Childhood Type 1 Diabetes Tied to Higher Risk of Later Psychiatric Diagnoses

A childhood diagnosis of type 1 diabetes (T1D) may increase risk of later psychiatric conditions, according to a study published online July 17 in&nbsp;Nature Mental Health.Tomáš Formánek, from the University of Cambridge in the United Kingdom, and colleagues used Czech national register data to identify children (aged ≤14 years) with

HealthDay 23 July at 10.27 PM

Long-Term Sulfonylurea Use Tied to Impaired Awareness of Hypoglycemia

The prevalence of impaired awareness of hypoglycemia (IAH) is high among patients using sulfonylureas long term, according to a study published in the July/August issue of the&nbsp;Annals of Family Medicine.Hsiang-Ju Cheng, M.D., from the National Cheng Kung University in Tainan, Taiwan, and colleagues investigated the relationship bet

HealthDay 23 July at 03.45 PM

Link Between T2DM, Spinal Degenerative Disorder May Be Method-Dependent

The association between type 2 diabetes mellitus (T2DM) and spinal degenerative disorders (SDDs) may be method-dependent, according to a study published online July 3 in The Journal of Bone &amp; Joint Surgery.Ming-Xiang Zou, M.D., Ph.D., from the University of South China in Hengyang, and colleagues examined and compared the associati

HealthDay 22 July at 09.49 PM

2011 to 2023 Saw Increase in New GLP-1 Receptor Agonist Prescriptions

From 2011 to 2023, there was an increase in new glucagon like peptide 1 receptor agonist (GLP-1RA) prescriptions, according to a research letter published online July 23 in the Annals of Internal Medicine.Yee Hui Yeo, M.D., from Cedars-Sinai Medical Center in Los Angeles, and colleagues examined nationwide trends in GLP-1RA prescription

HealthDay 19 July at 03.59 PM

Sleep Apnea Increases Risk for Cardiovascular Risk Factors and Events

Obstructive sleep apnea (OSA) is associated with an increased risk for cardiovascular disease (CVD) in adults, even those younger than 40 years, according to a study published online June 6 in the&nbsp;Journal of the American Heart Association.Chance Strenth, Ph.D., from University of Texas Southwestern Medical Center Dallas, and collea

HealthDay 19 July at 03.46 PM

Irregular Sleep Duration Tied to Increased Risk for Developing Diabetes

Irregular sleep duration is associated with elevated diabetes risk, according to a study published online July 17 in Diabetes Care.Sina Kianersi, Ph.D., from Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues examined the association between irregular sleep duration and incident diabetes among 84,421 U.K.

HealthDay 18 July at 03.46 PM

Accelerated Progression to T1D During Pandemic Seen for Presymptomatic Youth

For youth with presymptomatic type 1 diabetes, the COVID-19 pandemic was associated with accelerated progression to clinical disease, especially among those with COVID-19 infection, according to a research letter published online July 15 in the Journal of the American Medical Association.Nadine Friedl, from the Institute of Diabetes R

HealthDay 17 July at 03.14 PM

Aging Into Medicare Tied to Higher Drug Costs for People With Diabetes

As people with diabetes age into Medicare, they face increased quarterly out-of-pocket costs for medication, according to a study published online July 9 in&nbsp;JAMA Network Open.Douglas Barthold, Ph.D., from the University of Washington in Seattle, and colleagues examined whether reaching age 65 years is associated with changes in

HealthDay 16 July at 03.29 PM

Suicidal Ideation, Behaviors Not Increased With GLP-1 RAs for Seniors With T2D

For older adults with type 2 diabetes (T2D), use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) is not associated with a significantly increased risk for suicidal ideation and behaviors, according to a study published online July 16 in the Annals of Internal Medicine.Huilin Tang, from the University of Florida College of Phar

HealthDay 16 July at 03.26 PM

Certain Diets May Protect Against Heart Disease With Type 1 Diabetes

Certain dietary patterns may protect against inflammation and heart disease in adults with type 1 diabetes, according to a study presented during NUTRITION 2024, the annual meeting of the American Society for Nutrition, held from June 29 to July 2 in Chicago.Arpita Basu, Ph.D., from the University of Nevada in Las Vegas, and colleagues used dat

HealthDay 15 July at 10.00 PM

Metformin, SGLT2 Inhibitors Exhibit Significantly Lower Dementia Risk

Compared with other antidiabetic classes, metformin and sodium glucose co-transporter-2 inhibitors (SGLT2is) exhibit significantly lower dementia risk, according to a review published online May 3 in the American Journal of Preventive Medicine.Yongjun Sunwoo, from the College of Pharmacy at Kyung Hee University in Seoul, South Korea, an

HealthDay 12 July at 10.21 PM

More Women Than Men Experience Nonphysical Violence in Health Care Workforce

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

HealthDay 12 July at 10.16 PM

Only One-Quarter of Patients Still Taking Semaglutide for Weight Loss Two Years Later

Three of four patients stop taking semaglutide (Ozempic or Wegovy) two years after being prescribed the glucagon-like peptide-1 receptor agonist (GLP-1 RA) for weight loss, according to new analysis conducted by Prime Therapeutics and Magellan Rx Management (MRx).For the review, pharmacy and medical claims data for 3,364 people with insurance pl

HealthDay 12 July at 03.25 PM

Parents' Weight Status at Age 17 Correlates to Offspring Weight at 17

The weight status of parents at 17 years of age is associated with obesity risk for both female and male offspring, according to a study published online June 28 in&nbsp;JAMA Network Open.Gabriel Chodick, Ph.D., from Tel Aviv University in Israel, and colleagues assessed the heritability of obesity. The analysis included 447,883 offspri

HealthDay 12 July at 12.36 PM

New Report Calls for More Research on Women's Health Issues

A new report finds research is sorely lacking on how chronic illnesses affect women, and it urged government agencies to do more to investigate how these diseases strike women differently.The National Academies of Sciences, Engineering and Medicine <a href="https://nap.nationalacademies.org/catalog/27757/advancing-research-on-chronic-conditions-

HealthDay 11 July at 04.04 PM

GLP-1 RAs May Reduce Risk for Some Obesity-Linked Cancers Versus Insulin in T2D

For patients with type 2 diabetes (T2D), glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are associated with a reduced risk for 10 of 13 obesity-associated cancers (OACs) compared with insulin, according to a study published online July 5 in JAMA Network Open.Lindsey Wang, from Case Western Reserve University School of Medicine

HealthDay 11 July at 03.40 PM

Testosterone Tied to Incidence, Progression of Metabolic Syndrome

Testosterone is associated with a greater risk for development and progression of metabolic syndrome, particularly in transmasculine individuals, according to a study published online July 2 in&nbsp;JAMA Network Open.Leila Hashemi, M.D., from the David Geffen School of Medicine in Los Angeles, and colleagues assessed whether gender-af

HealthDay 10 July at 03.58 PM

Study Looks at Impact of Incentivizing Smoking Cessation in Addition to Usual Care

Incentivizing smoking cessation increases smoking cessation through 12 weeks, but not at 26 weeks, when missing data are treated as smoking, according to a study published online July 2 in JAMA Network Open.Darla E. Kendzor, Ph.D., from the University of Oklahoma Health Sciences Center in Oklahoma City, and colleagues randomly assign

HealthDay 10 July at 03.18 PM

Delaying Diabetes Progression After Impaired Glucose Improves Long-Term Outcomes

Maintaining several years of nondiabetes status after impaired glucose tolerance (IGT) diagnosis is associated with a significantly lower risk for poor long-term outcomes, according to a study published online July 9 in&nbsp;PLOS Medicine.Xin Qian, from the Chinese Academy of Medical Sciences and Peking Union Medical College in Beiji

HealthDay 09 July at 03.42 PM

Semaglutide Cuts MACE in People With Overweight, Obesity, Regardless of HbA1c

Semaglutide reduces cardiovascular events, regardless of baseline glycated hemoglobin (HbA1c), among people with overweight or obesity and established atherosclerotic cardiovascular disease, according to a study published online June 22 in Diabetes Care.Ildiko Lingvay, M.D., from the University of Texas Southwestern Medical Center in Da

HealthDay 08 July at 09.38 PM

Significantly More Weight Loss Seen With Tirzepatide Versus Semaglutide

Tirzepatide is associated with significantly greater weight loss than semaglutide for adults with overweight or obesity, according to a study published online July 8 in JAMA Internal Medicine.Patricia J. Rodriguez, Ph.D., from Truveta Inc. in Bellevue, Washington, and colleagues compared on-treatment weight loss and rates of gastrointest

HealthDay 05 July at 02.26 PM

Postpandemic Physician Revenue Recovery Varies by Specialty, Practice Type

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

HealthDay 03 July at 08.32 PM

Semaglutide Linked to Nonarteritic Anterior Ischemic Optic Neuropathy

Semaglutide is associated with nonarteritic anterior ischemic optic neuropathy (NAION) among patients with type 2 diabetes (T2D) and those with overweight/obesity, according to a study published online July 3 in JAMA Ophthalmology.Jimena Tatiana Hathaway, M.D., M.P.H., from the Harvard T.H. Chan School of Public Health in Boston, and

HealthDay 03 July at 12.21 PM

FDA Bans Food Additive Found in Sports Drinks, Sodas

A regulation allowing the use of brominated vegetable oil in food was revoked Tuesday by the U.S. Food and Drug Administration after the agency concluded the additive was unsafe for human consumption.Brominated vegetable oil (BVO) contains bromine, which is found in fire retardants. Small quantities of BVO have been used legally in some citrus

HealthDay 02 July at 04.01 PM

Mean Cost of Bringing New Drug to U.S. Market Is $879.3 Million

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

HealthDay 01 July at 05.50 PM

American Diabetes Association, June 21-24

The annual meeting of the American Diabetes Association was held this year from June 21 to 24 in Orlando, Florida, drawing more than 15,000 participants from around the world, including clinicians, academicians, allied health professionals, and others interested in diabetes. The conference highlighted the latest advances in di

HealthDay 01 July at 03.33 PM

Few With Type 2 Diabetes Receive Guideline-Recommended CKD Screening

Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study published online June 26 in JAMA Network Open.Daniel Edmonston, M.D., from the Duke University School of Medicine in Durham, North Carolina, and colleagues conducted a retrospective cohort study t

HealthDay 27 June at 03.21 PM

ADA: Bisphenol A Linked to Reduced Peripheral Insulin Sensitivity

Bisphenol A (BPA) administration is associated with reduced peripheral insulin sensitivity among healthy adults, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.Adam Seal, Ph.D., from the California Polytechnic State University in San Luis Obispo, and collea

HealthDay 27 June at 03.16 PM

ADA: Inhaled Insulin Shows Promise for Adults With Type 1 Diabetes

Inhaled insulin is associated with improved hemoglobin A1c (HbA1c) levels over 16 weeks among adults with type 1 diabetes when compared to usual care, according to a study presented at the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.Irl B. Hirsch, M.D., from the University of Washington in S

HealthDay 26 June at 03.26 PM

ADA: Semaglutide Similarly Effective in Men, Women With Obesity-Linked Heart Failure

For patients with obesity-related heart failure with preserved ejection fraction (HFpEF), semaglutide reduces body weight to a greater extent in women but yields similar improvements in heart failure-related symptoms in men and women, according to a study published online June 23 in the Journal of the American College of Cardiology to coinc

HealthDay 26 June at 03.26 PM

ADA: Tirzepatide Reduces Apnea-Hypopnea Index in Moderate-to-Severe OSA

Tirzepatide reduces the apnea-hypopnea index (AHI) among individuals with moderate-to-severe obstructive sleep apnea and obesity, according to a study published online June 21 in the New England Journal of Medicine to coincide with the annual meeting of the American Diabetes Association, held from June 21 to 24 in Orlando, Florida.At

HealthDay 26 June at 03.25 PM

Dysbiosis in Phylogenetically Diverse Species Associated With Type 2 Diabetes

The gut microbiome has a potential functional role in the pathogenesis of type 2 diabetes (T2D), according to a study published online June 25 in Nature Medicine.Zhendong Mei, Ph.D., from Brigham and Women's Hospital in Boston, and colleagues analyzed 8,117 shotgun metagenomes from 10 cohorts of individuals with T2D, prediabetes, and

HealthDay 25 June at 03.01 PM

Intermittent Fasting Aids Early Diabetes Outcomes More Than Drugs

Intermittent fasting may be a more effective intervention than drugs for people with early diabetes and either obesity or overweight, according to a study published online June 21 in&nbsp;JAMA Network Open.Lixin Guo, M.D., from the Chinese Academy of Medical Sciences in Beijing, and colleagues evaluated the effect of intermittent fasti

HealthDay 24 June at 03.23 PM

U.S. Supreme Court Agrees to Hear Case on Medical Care for Transgender Youth

The U.S. Supreme Court announced Monday that it would hear a case on a Tennessee law that bans transgender minors from receiving certain medical treatments in that state.The banned treatments include puberty-blocking drugs or hormonal therapies.It's the

HealthDay 24 June at 03.15 PM

Acupuncture Reduces Endocrine Symptoms, Hot Flashes in Breast Cancer

A 10-week acupuncture intervention significant reduces endocrine symptoms and hot flashes among women with breast cancer receiving endocrine therapy (ET), according to a study published online June 24 in Cancer.Weidong Lu, M.P.H., Ph.D., from the Dana Farber Cancer Institute in Boston, and colleagues enrolled 158 patients with stage 0 t

HealthDay 21 June at 03.36 PM

Timing of Metformin Important in Metformin-Treated Type 2 Diabetes

Glucose lowering by metformin is greater when given before enteral glucose among patients with type 2 diabetes controlled by metformin monotherapy, according to a study recently published in Diabetologia.Cong Xie, Ph.D., from the University of Adelaide in Australia, and colleagues studied 16 participants with type 2 diabetes that was re

HealthDay 21 June at 11.43 AM

WHO, Lilly Issue Warnings About Fake Weight-Loss Drugs

Both the World Health Organization and Eli Lilly warned Thursday that consumers should avoid fake versions of weight-loss drugs that are circulating in numerous countries.The WHO warning said that the inter

HealthDay 20 June at 08.56 PM

2021 to 2022 Saw Decrease in Telemedicine Use in Past 12 Months

From 2021 to 2022, there was a decrease in the percentage of adults who used telemedicine in the past 12 months, according to the June 20 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Jacqueline W. Lucas, M.P.H., and Xun Wang, from the National Center for Health Statistics in Hyattsvil

HealthDay 20 June at 08.50 PM

Timing of Exercise Significant for Obesity, Metabolic Impairment

For sedentary adults with obesity/overweight and metabolic impairments, the timing of moderate-to-vigorous physical activity (MVPA) is significant, with a beneficial effect on glucose homeostasis for accumulation of more MVPA in the evening, according to a study published online June 10 in Obesity.Antonio Clavero-Jimeno, from the Univ

HealthDay 20 June at 03.46 PM

Endocrine Society, June 1-4

The annual meeting of the Endocrine Society (ENDO 2024) was held from June 1 to 4 in Boston, attracting approximately 7,000 participants, including clinicians, academicians, allied health professionals, and others interested in endocrine and metabolic disorders. The conference highlighted recent advances in the diagnosis and

HealthDay 19 June at 04.04 PM

Type of Educational Institution Attended Linked to Health Outcomes

The type of educational institution attended is associated with multiple health outcomes in midlife, according to a study published online June 18 in the Journal of Epidemiology &amp; Community Health.Keyao Deng, from University College London, and colleagues examined associations between the type of high school or university attende

HealthDay 19 June at 03.43 PM

Benefits of Roux-en-Y Gastric Bypass Sustained in the Long Term

Roux-en-Y gastric bypass (RYGB) is successful in achieving long-term sustained weight loss and diabetes remission, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.John Nguyen-Lee, M.D., from the Geisinger Medical Center in Danville, Pennsylva

HealthDay 18 June at 09.11 PM

Approximately 7 Percent of U.S. Population Uninsured in 2023

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

HealthDay 18 June at 03.32 PM

Continuing Metformin in Pregnancy Has Little Effect on Nonlive Birth

Continuing metformin and adding insulin in early pregnancy does not significantly alter the risk for nonlive birth or live birth with congenital malformations compared with switching to insulin monotherapy, according to a study published online June 18 in the Annals of Internal Medicine.Yu-Han Chiu, M.D., Sc.D., from the Harvard T.H. C

HealthDay 18 June at 09.50 AM

Pandemic-Era Tax Credits Made Healthcare More Affordable, But They're Set to Expire

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

HealthDay 17 June at 10.55 PM

Paternal Metformin Use Not Linked to Major Congenital Malformations

Paternal use of metformin in monotherapy is not associated with an increased risk for major congenital malformations (MCMs), according to a study published online June 18 in the Annals of Internal Medicine.Ran S. Rotem, Sc.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues examined the association between p

HealthDay 17 June at 10.53 PM

1999 to 2020 Saw Diet Quality Improve Among U.S. Adults

From 1999 to 2020, diet quality improved among U.S. adults, according to a study published online June 18 in the Annals of Internal Medicine.Junxiu Liu, Ph.D., from the Icahn School of Medicine at Mount Sinai in New York City, and Dariush Mozaffarian, M.D., Dr.P.H., from Tufts University in Boston, examined trends in diet quality by rac

HealthDay 17 June at 10.51 PM

Meal Replacement + Financial Incentives Beneficial for Teens With Obesity

For adolescents with severe obesity, meal replacement therapy (MRT) plus financial incentives (FIs) yield a greater reduction in body mass index (BMI) and total body fat mass than MRT alone, according to a study published online June 17 in JAMA Pediatrics.Amy C. Gross, Ph.D., from the University of Minnesota Center for Pediatric Obesity

HealthDay 17 June at 03.37 PM

Bariatric Surgery Cuts Conversion to Diabetes Over Long-Term Follow-Up

Bariatric surgery significantly decreases the conversion from prediabetes to type 2 diabetes, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.John Nguyen-Lee, M.D., from the Geisinger Medical Center in Danville, Pennsylvania, and colleagues eval

HealthDay 14 June at 03.34 PM

1990 to 2019 Saw Increase in Life Expectancy in Seniors With T1DM

From 1990 to 2019, there was an increase in life expectancy in older people with type 1 diabetes mellitus (T1DM), according to a study published online June 12 in The BMJ.Kaijie Yang, from the First Hospital of China Medical University in Shenyang, and colleagues estimated the burden, trends, and inequalities of T1DM among older adults

HealthDay 13 June at 10.58 PM

Health Care Spending Growth Projected to Outpace GDP to 2032

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

HealthDay 12 June at 10.42 PM

Adverse Social Determinants of Health Linked to Prediabetes in Teens

Adverse social determinants of health (SDOH) are associated with higher prevalence of prediabetes among adolescents, according to a study published online June 11 in JAMA Network Open.Caleb Harrison, from the UPMC Children's Hospital of Pittsburgh, and colleagues examined the prevalence of prediabetes by presence or absence of advers

HealthDay 12 June at 03.05 PM

Adverse Effects of Medical Treatment Increasing Worldwide

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

HealthDay 12 June at 02.52 PM

ENDO: Novel Male Contraceptive Gel May Achieve Faster Sperm Suppression

A novel male contraceptive gel suppresses sperm production faster than other hormone-based methods for male birth control, according to a phase 2 study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Danielle Gross, from the Eunice Kennedy Shriver National Institute of Child Health and Human Developme

HealthDay 11 June at 03.45 PM

ENDO: Teprotumumab Shows Long-Term Efficacy for Thyroid Eye Disease

Most patients with thyroid eye disease treated with teprotumumab do not require additional treatments nearly two years later, according to a study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston, and simultaneously published online June 2 in&nbsp;Thyroid.George J. Kahaly, M.D., Ph.D., from the

HealthDay 11 June at 03.42 PM

ENDO: Early Menopause Tied to Heightened Risk for Breast, Ovarian Cancer

Women with early menopause have a two times greater risk for breast cancer and a nearly four times higher risk for ovarian cancer, according to a study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Kristina&nbsp;L. Allen-Brady, Ph.D., M.P.H., from University of Utah in Salt Lake City, and colleagues i

HealthDay 10 June at 09.50 PM

Insulin-Treated T2D Patients Unwilling to Participate in Intensive Lifestyle Intervention

For adults with advanced, insulin-treated type 2 diabetes (T2D), willingness to participate in an intensive lifestyle intervention (ILI) is very low, according to a research letter published online June 5 in Diabetes, Obesity and Metabolism.Cathy J. Sun, M.D., from The Ottawa Hospital in Ontario, Canada, and colleagues designed an ILI p

HealthDay 10 June at 03.28 PM

Greater Reduction Seen in Mortality With Bariatric Surgery Than GLP-1 RAs

Bariatric metabolic surgery (BMS) is associated with a greater reduction in mortality than glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment among adults with a diabetes duration of 10 years or less, according to a study published online June 7 in JAMA Network Open.Dror Dicker, M.D., from Rabin Medical Center in Petah Tikva,

HealthDay 10 June at 03.22 PM

Vitamin D Suggested for Children, Seniors, Those With High-Risk Prediabetes

Empiric vitamin D supplementation is suggested for those aged 1 to 18 years, those older than 75 years, those who are pregnant, and those with high-risk prediabetes, according to an Endocrine Society clinical practice guideline published online June 3 in the Journal of Clinical Endocrinology &amp; Metabolism.Marie B. Demay, M.D., from M

HealthDay 07 June at 03.34 PM

ENDO: Cardiovascular Events Occur Less Often With GLP1-RA, SGLT-2i for T2D, Liver Disease

For adults with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), glucagon-like peptide 1 receptor agonists (GLP-1 RA) and sodium-glucose cotransporter 2 inhibitors (SGLT-2i) are associated with reduced risk of cardiovascular (CV) events compared with dipeptidyl peptidase 4 inhibitors (DPP-4i), according to a st

HealthDay 07 June at 03.33 PM

Isotretinoin Effective for Acne in Those Receiving Gender-Affirming Therapy

Isotretinoin is well tolerated and effective for individuals receiving masculinizing gender-affirming hormonal therapy who have acne, according to a study published online May 29 in JAMA Dermatology.James Choe, from Brigham and Women's Hospital in Boston, and colleagues examined clinical outcomes of isotretinoin among transgender and gen

HealthDay 07 June at 03.31 PM

Metabolic Impact on Offspring Similar for Frozen, Fresh Embryo Transfer

For glucose and lipid profiles during early childhood, the impact of frozen embryo transfer (FET) is comparable to that of fresh embryo transfer, according to a study published online June 6 in PLOS Medicine.Wei Zhou, from Shandong University in Jinan, China, and colleagues compared the metabolic profiles of children born after frozen ve

HealthDay 06 June at 03.55 PM

Smoking Cessation Aids Equally Effective in Those With Mental Health Conditions

Popular smoking cessation aids are equally effective in those with or without a history of mental health conditions, according to a study published online June 4 in&nbsp;PLOS Mental Health.Sarah E. Jackson, Ph.D., from University College London, and colleagues examined whether the real-world effectiveness of popular smoking cessation a

HealthDay 05 June at 03.23 PM

ENDO: Crinecerfont Aids Patients With Congenital Adrenal Hyperplasia

Crinecerfont results in a greater decrease from baseline in the mean daily glucocorticoid dose among patients with congenital adrenal hyperplasia (CAH), according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Richa

HealthDay 04 June at 10.28 PM

Excess Mortality Persisted in Western World From 2020 Through 2022

Excess mortality persisted in 2020 through 2022 in the Western world, according to a study published online June 3 in BMJ Public Health.Saskia Mostert, M.D., from Amsterdam UMC, and colleagues explored excess mortality in the Western world from 2020 to 2022 using all-cause mortality reports abstracted from the "Our World in Data" databa

HealthDay 04 June at 03.49 PM

Diabetes Tied to Higher Prevalence of Overactive Bladder

Markers of diabetes are positively associated with overactive bladder (OAB), according to a study published online April 28 in&nbsp;Frontiers in Endocrinology.Qingliu He, from Jinjiang Municipal Hospital in Quanzhou, China, and colleagues used data from six cycles of the U.S. National Health and Nutrition Examination Survey (23,863 part

HealthDay 03 June at 09.12 PM

9.6 Percent of Medical Visits Took Place Via Telehealth in 2021

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

HealthDay 03 June at 03.53 PM

Plozasiran Reduces Triglyceride Levels in Mixed Hyperlipidemia

For individuals with mixed hyperlipidemia, plozasiran reduces triglyceride levels at 24 weeks, according to a study published online May 28 in the New England Journal of Medicine.Christie M. Ballantyne, M.D., from the Baylor College of Medicine and Texas Heart Institute in Houston, and colleagues conducted a 48-week, randomized trial ass

HealthDay 31 May at 03.49 PM

BMI Cutoff of 30 for Obesity May Be Too High for Middle-Aged, Older Adults

The optimal body mass index (BMI) cutoff point appears to be 27 kg/m2 for detecting obesity in middle-aged and older adults, according to a study presented at the annual meeting of the European Congress on Obesity, hosted by the European Association for the Study of Obesity from May 12 to 15 in Venice, Italy.Marwan El Ghoch, M.D., from

HealthDay 31 May at 03.43 PM

Semaglutide Cuts Risk for Kidney Outcomes, Death in CKD With T2DM

For patients with type 2 diabetes and chronic kidney disease, semaglutide reduces the risk for clinically important kidney outcomes and death from cardiovascular causes, according to a study published online May 24 in the New England Journal of Medicine to coincide with the annual European Renal Association Congress, held from May 23 to 26 in S

HealthDay 31 May at 03.41 PM

Weight Navigation Program Boosts Use of Weight Management Treatments

A primary care-based weight navigation program (WNP) is feasible and associated with greater use of weight management treatments (WMT) and weight loss, according to a study published online May 21 in JAMA Network Open.Dina H. Griauzde, M.D., from the University of Michigan Medical School in Ann Arbor, and colleagues examined the associat

MedScape 30 May at 07.59 AM

Novel Score Predicts Weight Loss With Semaglutide in T2D

The individualized metabolic surgery score could help set realistic weight loss targets with semaglutide in patients with type 2 diabetes and obesity.

HealthDay 29 May at 09.17 PM

2007 to 2019 Saw Increase in Inflation-Adjusted Health Care Spending

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

HealthDay 29 May at 03.06 PM

Demographic, Clinical, Financial Factors Tied to GLP-1 Agonist Discontinuation

Specific demographic, clinical, and financial characteristics are associated with glucagon-like peptide 1 (GLP-1) receptor agonist discontinuation, according to a research letter published online May 24 in&nbsp;JAMA Network Open.Duy Do, Ph.D., from the Evernorth Research Institute in St. Louis, and colleagues estimated the prevalence

MedScape 29 May at 09.42 AM

Can Curbing Sedentary Habits Mitigate Mortality Risk in T2D?

Patients with T2D who were sedentary for less than 6 hours a day had reduced mortality risk, and moderate physical activity enhanced longevity in those with more sedentary habits.

MedScape 29 May at 01.35 AM

Add-On to GLP-1s Yields Greater Weight Loss

Combination therapy of bupropion/naltrexone and GLP-1 receptor agonists showed a synergistic weight loss effect in individuals with obesity who responded poorly to GLP-1 monotherapy.

MedScape 28 May at 06.09 AM

How Can Patients With Diabetes and Obesity Lose Weight?

At a recent diabetes conference, experts debated the relative merits of exercise and medication for weight loss in this patient population.

MedScape 28 May at 06.04 AM

Analysis-Weight-loss Drug Forecasts Jump to $150 Billion as Supply Grows

As millions seek access to weight-loss drugs from Novo Nordisk and Eli Lilly, increasing supplies, possible wider usage and a growing number of would-be rivals are leading...

MedScape 27 May at 06.41 AM

CGM Aids in Detecting Early Gestational Diabetes

Glycemic patterns detected by continuous glucose monitoring (CGM) may help diagnose gestational diabetes earlier in pregnancy, which may help improve perinatal outcomes.

MedScape 25 May at 12.03 PM

Advisory Panel Votes Against Once-Weekly Insulin for T1D

A majority of the advisory committee voted that the benefits of insulin icodec don't outweigh the increased risk of hypoglycemia in type 1 diabetes.

HealthDay 24 May at 03.56 PM

Prenatal Exposure to Endocrine-Disrupting Chemicals Affects Child's Metabolic Health

Prenatal exposure to endocrine-disrupting chemicals (EDCs) is associated with adverse metabolic health in children, according to a study published online May 23 in JAMA Network Open.Nuria Güil-Oumrait, from the Barcelona Institute for Global Health in Spain, and colleagues examined associations of prenatal exposure to EDC mixtures with t

MedScape 24 May at 08.19 AM

Losing Muscle with GLP-1 RAs? There May be a Drug for That

Agents in development would preserve lean body mass and further promote fat loss in people taking new antiobesity medications for weight loss.

MedScape 23 May at 09.00 AM

More Weight Loss With Anti-Obesity Meds and Hormone Therapy?

Women who take hormone therapy showed a better response to GLP-1 drugs and lost more weight.

MedScape 23 May at 07.38 AM

Potential Precursor Lesion to Adrenal Tumors Identified

CPAs are the result of gene mutations leading to the development of two-layer nodules that have tumor-inducing and suppressing effects, suggested a new study.

HealthDay 22 May at 04.11 PM

GLP-1 Receptor Agonist Dispensing Up From 2020 to 2023 for Teens, Young Adults

For adolescents and young adults, glucagon-like peptide-1 receptor agonist (GLP-1 RA) dispensing increased from 2020 to 2023, according to a research letter published online May 22 in the Journal of the American Medical Association.Joyce M. Lee, M.D., M.P.H., from the University of Michigan Medical School in Ann Arbor, and colleagues

HealthDay 22 May at 03.50 PM

Global Life Expectancy, Disease Burden Set to Keep Improving

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

MedScape 22 May at 09.00 AM

Cortisol Test Confirms HPA Axis Recovery from Steroid Use

Early serum cortisol > 237 nmol/L validated as a screen for predicting the recovery of the HPA axis in patients on tapering regimes from long‐term chronic glucocorticoid therapy.

MedScape 22 May at 05.24 AM

Are Secondary Osteoporosis Causes Under-Investigated?

A single-center chart review found that postmenopausal women with osteoporosis may be started on antiresorptive therapy without having had secondary causes ruled out.

MedScape 22 May at 02.53 AM

Do Texts With Financial Incentives Aid Weight Loss in Men?

Text messages with financial incentives for men with obesity led to nearly two thirds losing 5% body weight over a year, and many men were from socially deprived groups.

MedScape 21 May at 09.05 AM

Social Media a 'Powerful' Way to Talk to Teens About Obesity

A short semaglutide video on TikTok drew close to 1 million views.

MedScape 21 May at 08.06 AM

Does Daytime Hypoglycemia Contribute to Impaired Awareness?

In older adults with T1D, less daytime hypoglycemia was the biggest predictor of improvements in IAH in a 6-month study.

MedScape 21 May at 07.04 AM

Nestle Set to Sell $5 Pizza, Sandwiches for Wegovy, Ozempic Users

Nestle will market a new, $5 line of frozen pizzas and protein-enriched pastas in the United States which it says it designed specifically for people taking drugs such as...

MedScape 21 May at 06.18 AM

Food Insecurity Quadruples Severe Hypoglycemia Risk in T2D

Both financial and physical food insecurity increased the risk, but standard questions didn't capture the latter.

HealthDay 20 May at 10.32 PM

Fezolinetant Safe, Effective for Moderate-to-Severe Menopause Hot Flashes

Fezolinetant is safe and effective for moderate-to-severe vasomotor symptoms (VMS), according to a study presented at the annual European Congress of Endocrinology, hosted by the European Society of Endocrinology from May 11 to 14&nbsp;in Stockholm.Angelica Lindén Hirschberg, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleague

HealthDay 20 May at 10.30 PM

Arm Fat May Predict Spinal Fracture Risk

Arm fat may predict risk for spinal fracture, according to a study presented at the annual European Congress of Endocrinology, hosted by the European Society of Endocrinology from May 11 to 14&nbsp;in Stockholm.Maria Eleni Chondrogianni, from the National and Kapodistrian University of Athens in Greece, and colleagues investigated the association

HealthDay 20 May at 03.47 PM

Guideline Developed for Glucocorticoid-Induced Adrenal Insufficiency

In a clinical guideline issued jointly by the European Society of Endocrinology and the Endocrine Society, recommendations are presented for the diagnosis and management of glucocorticoid-induced adrenal insufficiency. The guideline was published online May 8 simultaneously in the European Journal of Endocrinology and the Journal of Clinica

HealthDay 20 May at 03.44 PM

Blood Sugar Levels at Gestational Diabetes Diagnosis Predict Outcomes

Glucose above the diagnostic threshold at the time of gestational diabetes diagnosis is associated with worse neonatal outcomes, according to a study presented at the annual European Congress of Endocrinology, hosted by the European Society of Endocrinology from May 11 to 14&nbsp;in Stockholm.Catarina Cidade-Rodrigues, M.D., from Centro Hospitala

HealthDay 17 May at 08.59 PM

Slight Body Mass Gains in Middle Age May Cut Later Fracture Risk

People whose body mass index (BMI) slightly increases from normal weight to low-level overweight during 30 years of middle adulthood have a lower risk for fracture in later life, according to a study published online April 8 in&nbsp;Osteoporosis International.Zihao Xin, from the Boston University School of Public Health, and colleagues e

HealthDay 17 May at 04.27 PM

Men Face More Diabetes Complications Than Women

Men with diabetes have a greater risk for complications than women, irrespective of diabetes duration, according to a study published online May 16 in the&nbsp;Journal of Epidemiology &amp; Community Health.Alice A. Gibson, from the University of Sydney, and colleagues investigated sex differences in incident microvascular and macrovascu

MedScape 17 May at 08.22 AM

Why Insulin Resistance Is Higher in Men With Obesity?

In comparing women and men with obesity, researchers proposed that the latter are more insulin resistant due to less efficient inhibition of fat cell lipolysis.

MedScape 17 May at 05.04 AM

Switching Technologies in T1D May Offer Glycemic Benefit

An AID system improved glycemic outcomes in adults with long-standing T1D who struggled to meet their glycemic targets using insulin pumps and CGM.

MedScape 17 May at 04.05 AM

Cellular Therapy for Diabetes: What Progress Has Been Made?

Research into micro-, nano-, and macroencapsulation has led to historic moments, according to an expert endocrinologist.

MedScape 17 May at 03.09 AM

Does Eating Food With Emulsifiers Increase T2D Risk?

Food emulsifiers, a common ingredient in many ultraprocessed foods consumed by millions worldwide, increased the risk for incident type 2 diabetes.

HealthDay 16 May at 04.01 PM

Activity Tracker, Scale Plus Phone App May Aid Weight Loss

Weight loss is similar for individuals using a wireless feedback system (WFS) that provides daily information on lifestyle change and weight loss versus the same system augmented with human coaching, according to a study published online May 14 in the&nbsp;Journal of the American Medical Association. The research was published to coincide wit

MedScape 16 May at 11.17 AM

Is Body Fat a Better Measure of Obesity in Midlife Than BMI?

The conventional BMI cutoff for obesity may be better replaced with adiposity measures that accommodate changes in the body fat-to-muscle ratio that changes in the midlife years.

MedScape 16 May at 09.05 AM

Survey Suggests 1 in 8 US Adults May Have Used a GLP-1 Drug

A KFF poll also suggests half of the respondents who had tried these weight loss meds no longer took them, with many reporting difficulties paying for these drugs.

MedScape 16 May at 08.46 AM

Collaboration Tackles Steroid-Induced Adrenal Insufficiency

Best management practice for glucocorticoid-induced adrenal insufficiency has been developed jointly by endocrinologists in Europe and the United States.

MedScape 16 May at 06.45 AM

Lilly's Once-Weekly Insulin Top-Line Results Show Benefit

Phase 3 data for efsitora alfa showed noninferiority to once-daily basal insulins in two studies of people with type 2 diabetes.

HealthDay 15 May at 08.58 PM

Widening Disparities Seen in Youth Obesity

In the 2019 to 2020 school year, 20.9 percent of New York City elementary and middle school students had obesity, and 6.4 percent had severe obesity, according to a study published online May 15 in&nbsp;PLOS ONE.Kira L. Argenio, M.P.H., from the New York City Department of Health and Mental Hygiene, and colleagues estimated the preval

HealthDay 15 May at 03.40 PM

Text Messages + Financial Incentives Boost Weight Loss at 12 Months

Among men with obesity, an intervention with text messaging plus financial incentive significantly improves weight loss compared with a control group, according to a study published online May 14 in the&nbsp;Journal of the American Medical Association&nbsp;to coincide with the annual meeting of the European Congress on Obesity, hosted by the

HealthDay 15 May at 03.33 PM

AI-Informed Health App Aids Diabetes Outcomes

Use of an artificial intelligence (AI)-informed health app aids diabetes outcomes and cuts atherosclerotic cardiovascular disease (ASCVD) risk, according to a study presented at the annual meeting of the American Association of Clinical Endocrinology, held from May 9 to 11 in New Orleans.Paramesh Shamanna, M.D., from the Bangalore Diabetes Cent

HealthDay 15 May at 03.23 PM

GLP-1 Receptor Agonist Use Increases Likelihood of Antidepressant Prescription

Individuals taking glucagon-like peptide (GLP)-1 receptor agonists have a greater risk for subsequently being dispensed antidepressants, according to a study published online April 23 in&nbsp;Diabetes, Obesity, and Metabolism.Osvaldo P. Almeida, Ph.D., from University of Notre Dame in Fremantle, Australia, and colleagues assessed whet

MedScape 15 May at 09.04 AM

No Added Weight Loss Benefits Switching Healthy Diets?

Switching from one healthy weight loss diet to another did not overcome the typical weight loss plateau at 6 months in individuals with overweight and obesity.

MedScape 15 May at 08.14 AM

Tackling Lean Mass Loss When Weight Loss is Successful

The loss of lean mass has become a hot topic with new anti-obesity drugs, but such changes can occur with most successful weight loss interventions — without meaningful countermeasures.

MedScape 15 May at 05.14 AM

Setmelanotide Shows Promise in Hypothalamic Obesity

Treatment with setmelanotide, a melanocortin-4 receptor agonist, led to a significant reduction in BMI in a difficult-to-treat population of patients with hypothalamic obesity.

MedScape 15 May at 01.56 AM

No Shortage Of Wegovy Weight-loss Drug in Denmark, Novo Nordisk Says

Novo Nordisk does not expect a shortage of its Wegovy weight-loss drug in Denmark despite an earlier warning by the Danish Medicines Agency of strained supply of two...

HealthDay 14 May at 10.41 PM

Four in 10 Adults With Diabetes Report Taking a GLP-1 Receptor Agonist

One in eight adults (12 percent) say they have ever taken a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and 6 percent say they are currently using one, according to the results of a new KFF Health Tracking Poll, released May 10.Alex Montero, from KFF Health, and colleagues analyzed data collected April 23 to May 1, 2024, online and by te

MedScape 14 May at 05.58 PM

Eli Lilly Reaches Settlement With Spa Selling Mounjaro, Zepbound Knockoffs

Eli Lilly has entered into a settlement deal with a medi spa that had sold counterfeit versions of its popular diabetes drug Mounjaro and weight loss treatment Zepbound, the...

HealthDay 14 May at 03.54 PM

Most Slow Responders to Tirzepatide Do Lose Clinically Meaningful Weight

Among slow responders to tirzepatide treatment at week 12, 90 percent went on to achieve clinically meaningful weight reduction (≥5 percent) by week 72, according to a study presented at the annual meeting of the American Association of Clinical Endocrinology, held from May 9 to 11 in New Orleans.Kimberly Gudzune, M.D., from Johns Hopkins Univer

MedScape 14 May at 01.28 PM

Semaglutide CV Benefits Irrespective of Weight Lost?

Semaglutide remains effective for weight loss at 4 years in people with preexisting cardiovascular disease and overweight/obesity but without T2D and provides CV benefits regardless of weight.

MedScape 14 May at 10.43 AM

Weight Loss Maintained With Slow Taper of Semaglutide

A digital lifestyle program used in combination with semaglutide from low starting dose shows participants can maintain weight loss after tapering and stopping the drug, irrespective of starting BMI.

MedScape 14 May at 09.47 AM

Bone Quality Key in Mild Autonomous Cortisol Secretion

Small study finds that adrenalectomy improves bone quality but not density in MACS, suggesting that the former is key to the increased fracture risk in the condition.

MedScape 14 May at 05.59 AM

Does Childhood Weight Alter Health Risks in Adults?

Self-perceived weight as a child may influence risks for all-cause mortality and incident cardiovascular disease in adults who are overweight or obese.

MedScape 14 May at 05.41 AM

Vosoritide Boosts Growth in Several Short Stature Conditions

Already approved for treating achondroplasia, the drug also appears to accelerate growth in children with other genetic growth-limiting conditions.

HealthDay 13 May at 10.34 PM

Physicians With Disabilities May Experience Depersonalization

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

MedScape 13 May at 09.17 AM

Food Marketing on Video Games Tied to Teen Eating Behavior

Exposure to branded products on live-streaming video game platforms may drive excess eating and weight gain.

MedScape 13 May at 06.02 AM

CAH Treatment 'Struggle' Points to Unmet Need

Inadequate current treatment of congenital adrenal hyperplasia using glucocorticoids suggested potential benefit of investigational drug.

HealthDay 10 May at 03.57 PM

Cardiovascular, Kidney, and Metabolic Syndrome Highly Prevalent in the U.S.

Cardiovascular, kidney, and metabolic (CKM) syndrome is highly prevalent in the United States, with more than 90 percent of adults meeting the criteria for stage 1 or higher, according to a research letter published online May 8 in the Journal of the American Medical Association.Rahul Aggarwal, M.D., from Harvard Medical School in Boston

MedScape 10 May at 02.43 PM

If at First Tirzepatide Doesn't Succeed, Keep Trying

Treatment guidelines that advise stopping a weight-loss drug if weight loss isn't achieved by 12 weeks don't account for the titration required, investigator says.

HealthDay 10 May at 12.42 PM

Cyberattack Cripples Major U.S. Health Care Network

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

MedScape 10 May at 12.04 PM

Teprotumumab Treats Thyroid Eye Disease Across Age

Findings refute those of a prior study suggesting a better response in older vs younger patients.

MedScape 10 May at 07.46 AM

Prevention of Diabetes Complications Lags in Latin America

Data suggest a lack of compliance with assessments to prevent ophthalmologic and neuropathic complications of diabetes in several countries.

MedScape 10 May at 05.03 AM

Arsenic in Community Water Raises Type 2 Diabetes Risk

Even low levels of arsenic in drinking water, below the current regulatory limits, increased the risk for incident T2D in racially and ethnically diverse urban US communities.

MedScape 10 May at 01.54 AM

Kids and Anti-Obesity Meds: Real-World Challenges

The new anti-obesity drugs could be as beneficial for the treatment of adolescents as adults — but obstacles may require creative strategies.

HealthDay 09 May at 09.03 PM

Those With Limited English Proficiency Face Barriers to Telehealth

For individuals with limited English proficiency, there are disparities in telehealth access, as well as worse video visit experiences, according to a research letter published May 9 in&nbsp;JAMA Network Open.Jorge A. Rodriguez, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from 24,453 adult participants in

HealthDay 09 May at 08.57 PM

Researchers Quantify the Risk for Diabetes After Gestational Diabetes

Gestational diabetes is associated with an increased risk for subsequent diabetes, with higher risk for gestational diabetes in second pregnancy and in both first and second pregnancies, according to a study published online May 9 in JAMA Network Open.Joseph Mussa, from McGill University in Montreal, and colleagues compared the hazards

HealthDay 09 May at 06.04 PM

More Than 200 Insulin Pump Users Injured After App Causes Malfunction

The U.S. Food and Drug Administration has issued a Class 1 recall -- its most urgent kind -- for an IOS app linked to a specific kind of insulin pump used by people with diabetes.The <a href="https://www.fda.gov/medical-devices/medical-device-recalls/tandem-diabetes

HealthDay 09 May at 03.53 PM

Mortality Slightly Increased With Consumption of Ultraprocessed Foods

Mortality is slightly higher in association with a higher intake of ultraprocessed foods, according to a study published online May 8 in The BMJ.Zhe Fang, M.B.B.S., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues conducted a population-based cohort study to examine the association of ultraprocessed food cons

HealthDay 08 May at 10.09 PM

Distal Symmetric Polyneuropathy Often Undiagnosed

Distal symmetric polyneuropathy (DSP) is common and is frequently undiagnosed, according to a study published online May 8 in Neurology.Melissa A. Elafros, M.D., Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined whether data accurately reflect the prevalence, risk factors, and burden of DSP in the population.

MedScape 08 May at 03.19 PM

Tandem Recall Urges Updating App Used With Insulin Pump

The recall warns of a software glitch with the t:connect mobile app that can lead to battery failure of the t:slim X2 insulin pump.

MedScape 08 May at 10.22 AM

Don't Overlook Cardiovascular Risk in Type 1 Diabetes

A new review paper summarized what is and isn't known.

MedScape 08 May at 09.12 AM

Vitamin Shoppe's Telehealth Service to Provide Access to Weight-loss Drugs

Health and wellness products retailer Vitamin Shoppe said on Wednesday that subscribers to its telehealth service would have access to weight-loss medications such as...

MedScape 08 May at 09.00 AM

Free T4 Measure May Not Aid in Thyroid Function Testing

Low free T4 is common, but the incidence of central hypothyroidism is rare.

MedScape 08 May at 06.54 AM

Diabetic Neuropathic Pain: Which Treatments Work?

At a recent conference, experts reviewed the data about pharmaceutical treatments, topical medicines, and neuromodulation for this indication.

HealthDay 07 May at 03.02 PM

Time-Restricted Eating + High-Intensity Training Aids Women With Obesity, Inactivity

Combining time-restricted eating (TRE) with high-intensity functional training (HIFT) may have superior effects on body composition, lipid profile, and glucose regulation among inactive women with obesity compared with diet or exercise interventions alone, according to a study published online May 1 in PLOS ONE.Ranya Ameur, from Universi

MedScape 07 May at 09.35 AM

Continuous Glucose Monitors Gain Favor in Obesity

The off-label use of CGMs for people possibly on the verge of, but not yet diagnosed with, diabetes is seen as a potential tool to help reverse course; over-the-counter version highly anticipated.

MedScape 07 May at 06.11 AM

Why Do Some Obesity Interventions Work Longer Than Others?

The time to weight loss plateau is longer with both GLP-1 receptor agonists and bariatric surgery than with diets alone due to their effect on appetite, not energy expenditure.

HealthDay 06 May at 03.46 PM

Exposure to Food Additive Emulsifiers Linked to Risk for Type 2 Diabetes

Exposure to food additive emulsifiers is associated with an increased risk for type 2 diabetes, according to a study published in the May issue of The Lancet Diabetes &amp; Endocrinology.Clara Salame, Ph.D., from the Université Sorbonne Paris Nord and Université Paris Cité, and colleagues analyzed data from 104,139 adults enrolled in the

MedScape 06 May at 07.52 AM

Do People With Diabetes Need to Fast Longer Before Surgery?

New data find gastric contents after fasting aren't higher than nondiabetics, but an expert endocrinologist disputes that conclusion and GLP-1 agonists further complicate the picture.