The Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine, licensed in the United States to prevent smallpox and mpox, is well tolerated and seems effective in adolescents, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.Catherine Mary Healy

Implementation of an electronic health record (EHR) order set increases compliance with the recommended duration of prescribed antibiotics for children with acute otitis media (AOM), according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.Joana Dimo, D.

Women younger than 50 who used a levonorgestrel-releasing intrauterine device (IUD) had a significantly higher risk of breast cancer as compared with women who did not use hormonal contraceptives, a Danish registry study showed...

Rates of biochemical alcohol and drug screening are disproportionately higher among adolescent trauma patients who are from racial and ethnic minorities, have public or no insurance, or are female, according to a research letter published online Oct. 4 in JAMA Network Open.Jordan M. Rook, M.D., from the Greater Los Angeles Vetera

Exposure to maternal COVID-19 is not associated with abnormal neurodevelopmental screening results through 24 months postpartum, according to a study published online Oct. 16 in JAMA Network Open.Eleni G. Jaswa, M.D., from University of California, San Francisco, and colleagues assessed whether in utero exposure to maternal COVID-19 i

An estimated 4.22 million people in the U.S. had glaucoma and 1.49 million people had vision-affecting glaucoma in 2022, with Black adults approximately twice as likely as white adults to be affected, according to a meta-analysis...

The following contains links to social media websites including X, TikTok, Instagram, Facebook, and LinkedIn. It's pumpkin patch season, which means ... potential back injuries? @ladyspinedoc showed her audience how to lift...

Despite the uphill battle that most inventors must undertake to bring their innovations to market, the global market for medical device technologies was valued at $550 billion in 2021. By 2030, it is projected to reach $850 billion...

More vigilance may be needed regarding the amount of benzodiazepines being dispensed to older stroke survivors, though prescription patterns at the national level have improved in recent years. Medicare records showed that within...

For lung transplant recipients, exposure to higher air pollution levels was linked to an increased risk of death or graft failure, a retrospective cohort study found. Living in a zip code exposed to elevated ambient fine particulate...

An international team of researchers has developed a detailed atlas of early mammalian embryo development, revealing how chaotic cell divisions eventually form a consistent structure. Their findings highlight that chaos is essential in driving embryos toward an optimal, reproducible shape, offering insights into normal and abnormal development with potential applications in IVF and regenerative me

A Princeton-led team created the first detailed neuron-by-neuron map of an adult fruit fly brain, a significant step in neuroscience. This achievement provides a new tool for understanding complex brains, aiding future studies of human brain diseases.

Predicting which people with inflammatory rheumatic musculoskeletal diseases (I-RMDs) may experience flares after COVID-19 vaccination just got a bit easier, thanks to a new analysis of more than 7,000 European RMD patients...

The FDA approved a subcutaneous 24-hour continuous infusion of foscarbidopa and foslevodopa (Vyalev) for advanced Parkinson's disease, AbbVie announced Thursday. Foscarbidopa and foslevodopa are pro-drugs for carbidopa and levodopa...

Researchers using ultra-powered 7-Tesla MRI scanners found that damage to the brainstem, caused by severe COVID-19 infections, is linked to long-term physical and psychiatric symptoms. These findings help explain the lingering effects such as breathlessness, fatigue, and anxiety in patients, highlighting the importance of neuroinflammatory responses in the brainstem.

Researchers at the University of Pittsburgh report that deep brain stimulation (DBS) can immediately improve arm and hand strength weakened by traumatic brain injury or stroke, with promising results in both monkeys and humans. This approach may offer new hope for restoring motor functions, enhancing quality of life for patients with paralysis from brain injuries.

The Nobel Prize in Chemistry 2024 was awarded to David Baker, Demis Hassabis, and John Jumper for their breakthroughs in using AI to predict and design proteins. Their work holds significant promise for advancing drug development, environmental solutions, and new materials.

Crohn's disease, known for affecting the digestive tract, may also be linked to chronic back and joint pain. While primarily causing abdominal symptoms, many patients report back pain, suggesting a possible deeper connection.

Canada has one of the world's most permissive euthanasia systems, allowing it for non-terminal conditions like unmanageable pain. However, there is growing concern as many euthanasia cases are linked to social issues like poverty and homelessness, leading to ethical debates among doctors and policymakers.

The Gallup survey reveals that 1 in 5 U.S. adults reports daily feelings of loneliness, marking the highest rate in two years. Loneliness, which can severely impact mental health and life satisfaction, is described as a growing issue, with 52 million Americans still experiencing a sense of social disconnection.

The article discusses a new FDA rule requiring women aged 40 and older to receive notifications about dense breast tissue with their mammogram results. While this aims to help with early detection of breast cancer, some doctors argue that the notifications may cause confusion and lead to unnecessary tests, as there's no consensus on the need for additional screening for dense breasts.

Kamala Harris recently released her medical records, which show she is in excellent health with mild seasonal allergies and nearsightedness. Donald Trump, despite promising to do so, has not released his medical records in detail since 2018, leaving questions about his current health unanswered.

Elder care costs are rising faster than inflation, with the price of at-home care growing by 8.7% over the past year. Vice President Harris proposed a Medicare expansion to help caregivers, addressing a growing financial burden on millions of American families.

A CNBC investigation revealed a global black market for obesity drugs like Ozempic and Wegovy, where counterfeit and illegally diverted products are sold, often posing serious health risks to consumers. Criminal operations exploit the high demand for weight-loss medications, with products shipped from overseas, including China and Turkey, and authorities cracking down on the counterfeit trade.

A multi-state study, published in The Lancet, is one of the first real world data analyses of the effectiveness of the RSV—short for respiratory syncytial virus—vaccine. VISION Network researchers report that across the board these vaccines were highly effective in older adults, even those with immunocompromising conditions, during the 2023–24 respiratory disease season, the first season after RSV

If he wins next month's election, Donald Trump would be the oldest person in U.S. history to be elected president. Yet the 78-year-old Republican nominee refuses to disclose new details about his physical or mental well-being...

In its first three years of operation, Medicaid's primary care-focused Accountable Care Organizations (ACOs) in Massachusetts showed "no clear evidence of success" in improving asthma care for children, according to research led by the University of Massachusetts Amherst and UMass Chan Medical School-Baystate Health.

On 17 October 2024, Martina Lamberti publicly defended her Ph.D. thesis, "Know the Past to See the Future: Memory and Prediction in In-Vitro Cortical Neurons," at the University of Twente. Her research sheds light on how the brain predicts future events and forms memories. These findings could open new doors in understanding neurological conditions like dementia.

Acute pancreatitis (AP), which affects people of all ages, is one of the leading causes of hospital admission due to gastrointestinal diseases. Approximately 20% of patients develop moderate or severe acute pancreatitis, which carries extremely high mortality and disability rates. Even for those who recover, lifelong complications often follow, significantly affecting their quality of life.

California doctor Harjasleen Walia, MD, sued a Thai restaurant alleging that its "Dragon Balls" appetizer was so spicy it burned her vocal cords, esophagus, and the inside of her right nostril. The case is set to go to jury trial...

Among recipients with HIV, kidney transplantation from donors with HIV is noninferior to that from donors without HIV, according to a study published online Oct. 16 in the New England Journal of Medicine.Christine M. Durand, M.D., from Johns Hopkins University School of Medicine in Baltimore, and colleagues compared transplantation of

Excess body fat plays a role in postmenopausal hormone receptor-positive breast cancer, which could be underestimated using only body mass index (BMI), according to a study published online Oct. 17 in the Journal of Epidemiology and Community Health.Naiara Cubelos-Fernández, from the University of León Institute of Biomedicine in Spai

Stereotactic body radiotherapy (SBRT) is noninferior to conventional or moderately fractionated radiotherapy for localized prostate cancer (PC), according to a study published online Oct. 16 in the New England Journal of Medicine.Nicholas van As, from the Royal Marsden Hospital in London, and colleagues assessed whether SBRT is n

From 2013 to 2021, there was a decline in benzodiazepine initiation for post-acute ischemic stroke (AIS), according to a study published online Oct. 17 in Stroke.Victor Lomachinsky Torres, M.D., from Massachusetts General Hospital in Boston, and colleagues analyzed a 20 percent sample of U.S. Medicare claims from April 1, 2013, to Sep

A self-proclaimed Brazil-Italy collaboration enthusiast, researcher Laura Bolognesi created the B2AlzD2 Joint Lab at the Department of Pharmacy and Biotechnology of the Università di Bologna (UNIBO), the first Brazil-Bologna joint laboratory dedicated to the development of new drugs for the treatment of Alzheimer's disease. The partners include scientists from four Brazilian universities: the Fede

For patients with acute ischemic stroke (AIS), tenecteplase (TNK) has improved functional outcome and reduced disability and similar safety to alteplase (tissue plasminogen activator [TPA]), according to a study published online Oct. 16 in Neurology.Lina Palaiodimou, M.D., Ph.D., from the National and Kapodistrian University of Athens

Food allergy (FA)-related distress is common and varies across countries, according to a study published in the October issue of Allergy.Rebecca C. Knibb, Ph.D., from Aston University in the United Kingdom, and colleagues recruited 1,329 adults with FA and 1,907 caregivers of children with FA from more than 20 countries through patien

Neglected tropical diseases refer to a group of ailments that affect millions of people globally, often in poverty-stricken areas of the world, and yet don't receive the scientific attention they deserve. Schistosomiasis is one such disease—a persistent parasitic infection that affects an estimated 250 million people in 78 countries, particularly in Africa and Latin America.

THURSDAY, Oct. 17, 2024 (HealthDay News) -- In a recent study, half of all patients with sepsis admitted to an emergency department died within two years, but the predictive ability of a model was poor, according to a study presented at the European Emergency Medicine Congress, held Oct. 12 to 16 in Copenhagen, Denmark.Osama Bin Abdullah, M.D., Ph.D., from Slagelse Hospital in Denm

Is vaping finally losing its coolness for American teens? The latest tally of federal data finds that 550,000 school kids, mostly high schoolers, quit using e-cigarettes in 2024.

In a second letter to users of MiniMed 600 and 700 series insulin pumps, the company advises patients to carry backup batteries and change them immediately when “low battery pump” alert appears.

In people with epilepsy, progression of retinal neuroaxonal loss is detectable at short-term follow-up, according to a study published online Oct. 9 in Epilepsia.Livia Stauner, from LMU University Hospital in Germany, and colleagues examined the longitudinal dynamics of retinal neuroaxonal loss and possible driving factors in 44

Thousands more U.S. lives could have been saved with the use of COVID-19 convalescent plasma (CCP), according to a study published online Oct. 1 in the Proceedings of the National Academy of Sciences.

Paternal metformin use during the period of sperm development is not associated with an increased risk for congenital malformations in offspring, according to a study published online Oct. 16 in The BMJ.Lin-Chieh Meng, from the National Taiwan University, and colleagues examined the association between paternal metformin use and the r

Increased risk for autism appears to be linked to the Y chromosome, a Geisinger Health System study has found, offering a new explanation for the greater prevalence of autism in males. The results are published in Nature Communications.

Thousands more U.S. lives could have been saved with the use of COVID-19 convalescent plasma (CCP), according to a study published online Oct. 1 in the Proceedings of the National Academy of Sciences.Quigly Dragotakes, Ph.D., from Johns Hopkins School of Public Health in Baltimore, and colleagues conducted meta-analyses of randomized

In people with epilepsy, progression of retinal neuroaxonal loss is detectable at short-term follow-up, according to a study published online Oct. 9 in Epilepsia.

For patients with acute ischemic stroke (AIS), tenecteplase (TNK) has improved functional outcome and reduced disability and similar safety to alteplase (tissue plasminogen activator [TPA]), according to a study published online Oct. 16 in Neurology.

In a recent study, half of all patients with sepsis admitted to an emergency department died within two years, but the predictive ability of a model was poor, according to a study presented at the European Emergency Medicine Congress, held Oct. 12 to 16 in Copenhagen, Denmark.

A national recall of meat and poultry has been expanded to include close to 12 million pounds of products that may have been contaminated with listeria, U.S. health officials announced.

Nicotine pouches have overtaken cigarettes in youth popularity, as tobacco product use among US middle and high schoolers dropped to its lowest level in a quarter of a century, according to official data released Thursday.

Stereotactic body radiotherapy (SBRT) is noninferior to conventional or moderately fractionated radiotherapy for localized prostate cancer (PC), according to a study published online Oct. 16 in the New England Journal of Medicine.

Exposure to maternal COVID-19 was not associated with abnormal neurodevelopmental screening results through 24 months' postpartum, according to a cohort study in JAMA Network Open. In this video interview, researcher Eleni Greenwood...

Chemicals are omnipresent today. They enter our bodies through food, air or the skin. But how do these complex mixtures of chemicals affect our health? In a new study, a research team from the Helmholtz Centre for Environmental Research (UFZ) has shown that chemicals that occur in complex mixtures and in concentration ratios as found in humans act together.

The question of what causes complex neurological diseases such as Alzheimer's or multiple sclerosis continues to confound scientists and doctors, with the unknowns standing in the way of early diagnoses and effective treatments.

In a study believed to be the first of its kind published, a research team led by Johns Hopkins Medicine provides scientific evidence that a healthy diet may reduce the chance of low risk prostate cancer progressing to a more aggressive state in men undergoing active surveillance—a clinical option in which men with lower risk cancer are carefully monitored for progression in lieu of treatments tha

A new study, conducted by a group of researchers led by Penn Nursing and Perelman School of Medicine found a strong association between handheld cellphone use and risky driving behaviors among newly licensed teen drivers. The study, published online first in JAMA Network Open, used a smartphone telematics application to track the driving habits of hundreds of teens and identify potential safety ri

Three states are renewing a legal push to restrict access to the abortion medication mifepristone (Mifeprex), including reinstating requirements it be dispensed in person instead of by mail. The request from Kansas, Idaho, and...

Northwestern Medicine scientists have discovered how a protein in a deadly type of lung cancer can control how the immune system responds to the tumor, according to a study published in the Proceedings of the National Academy of Sciences.

Lumryz is the only FDA-approved once-at-bedtime oxybate treatment for cataplexy or excessive daytime sleepiness in children as young as 7 years with narcolepsy.

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine. The study, published in eClinicalMedicine, details an international, multicenter phase 2/3 clinical trial that found a combination of amubarvimab and romlusevimab did not reduce the occurrence of lo

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion. In response to incoming food, these hormones are secreted by rare hormone producing cells in the gut and play key roles in managing digestion and appetite.

Note that some links may require registration or subscription. Singer Liam Payne, a former member of the hit boy-band One Direction, died after reportedly falling from a hotel balcony in Argentina. (CNN) Standing desks may...

Consuming more ultra-processed foods—from diet sodas to packaged crackers to certain cereals and yogurts—is closely linked with higher blood sugar levels in people with type 2 diabetes, a team of researchers in nutritional sciences, kinesiology and health education at The University of Texas at Austin have found.

Playing video games may boost your cognitive abilities and exercise can play a role in improving your mental health, but not the other way around, a large-scale study has found.

The human brain is a complex organ with over 80 billion neurons. But it can still trip up when it comes to multitasking. Trying to send an email at the same time as talking to someone can almost be enough to short-circuit our synapses, leaving us distracted and prone to making mistakes.

Medicare Advantage plans have increased their use of prior authorization and appear to be targeting certain types of care -- such as expensive post-acute hospital care -- for coverage denials, according to a report issued...

A newly published study by Akshaya Bhagavathula, NDSU associate professor of epidemiology, highlights the growing disparities in substance use disorders (SUD) mortality in the United States.

A collaborative effort between engineers and biologists at the Hong Kong University of Science and Technology (HKUST) has uncovered a neuroprotective mechanism in spinal cord injury (SCI), shedding new light on therapeutic approaches to potentially benefit millions of patients worldwide.

Move more, quit smoking, lose weight: great resolutions, hard to keep. But does it get easier if there is a financial incentive in return? According to research by Radboud University and others, it can be an effective tool, although there are still some obstacles. They presented their findings this week in Economisch Statistische Berichten (ESB).

Scientists in the East of England have developed a way of using artificial intelligence to check for skin cancer, with the AI tool outperforming existing methods in a new study.

A new study conducted by SISSA's Laboratory of Cerebral Cortex Development and recently published in BMC Biology has led to a surprising revelation about the role of the FOXG1 gene: not only does it orchestrate development of the anterior brain by regulating RNA transcription, but its role includes direct regulation of RNA translation, i.e. protein production.

Cannabis is one of the most widely used drugs, with an estimated 219 million users globally in 2021, with the highest number of users in the Americas. It is also the most used drug among young people. In the U.S., cannabis use among young adults (age 19 to 22) reached a historically high level in 2021, with 42.6% reporting use in the past year.

The foundation for healthy eating behavior starts in infancy. Young children learn to regulate their appetite through a combination of biological, psychological, and sociological factors. In a new paper, researchers at the University of Illinois Urbana-Champaign propose a model that explores these factors and their interactions, providing guidelines for better understanding childhood appetite self

A research team led by Prof. Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the lipoprotein apolipoprotein E (ApoE). Their work appears in Science Advances.

Psychology experts in the UK and US have found there is "not enough evidence" to link social media use to mental health problems like anxiety and depression.

A new study from the Yale School of Public Health (YSPH) offers fresh insights into our understanding of colorectal cancer (CRC) that challenge the conventional right-sided and left-sided classifications of the disease.

Pediatric patients aged 10 to 19 years old diagnosed with COVID-19 have a higher risk of new-onset type 2 diabetes within six months compared to those diagnosed with other respiratory infections, according to researchers at Case Western Reserve University School of Medicine.

Some 1,100 people across Africa have died from mpox, the African Union's health agency said Thursday, warning that the epidemic was "going out of control" without further action.

A paper published in the American Journal of Infection Control describes efforts at a major children's hospital to assess and fulfill its staffing needs for infection prevention and control, highlighting the challenges of allocating sufficient resources to this important role.

An international team of neuroscientists, led by Duke-NUS Medical School, have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and regenerating brain cells.

Emotional eating and uncontrolled eating are more common in middle-aged women diagnosed with polycystic ovary syndrome (PCOS). In particular, psychological distress increased the long-term risk of disordered eating behavior. This finding is highlighted in a study by the University of Oulu and ODL Sports Clinic.

New Zealand adults are eating, on average, far more salt daily than international recommendations; however, takeaways frequently do not display salt content.

A study published in the journal Addiction has found that people with opioid or alcohol use disorder (OUD, AUD) who take Ozempic or similar medications to treat diabetic/weight-related conditions appear to have a 40% lower rate of opioid overdose and a 50% lower rate of alcohol intoxication than people with OUD and AUD who do not take Ozempic or similar medications.

It may soon be possible to determine which patients with a type of liver cancer called hepatocellular carcinoma would benefit from immunotherapy, according to a preclinical study by Weill Cornell Medicine investigators.

Glioblastomas are aggressive brain tumors with a median survival time of less than 22 months despite standard therapy including surgery, irradiation, and chemotherapy. It has become clear in recent years that not all cells within the brain tumor have an equal potential to divide and drive tumor growth.

A national recall of meat and poultry has been expanded to include close to 12 million pounds of products that may have been contaminated with listeria, U.S. health officials announced.In addition, the updated recall</a

Exposure to conversion practices targeting gender identity, sexual orientation, or both is associated with increased mental health symptoms in sexual and gender minorities.

Stereotactic body radiotherapy was associated with significantly better urinary continence and fewer sexual issues at 2 years than prostatectomy in patients with localized prostate cancer.

An active lifestyle is known to boost both mental and physical health, increasing life expectancy. It is often assumed that grandparents who care for their grandchildren engage in more activities, such as playing and going on outings, which should improve their health. However, researchers at the University of Alabama at Birmingham have found that grandparents who are heavily involved in the careg

From 1999 to 2019, there was a decrease in the sepsis-related mortality rate (SRMR) in children overall and across demographic groups, according to findings presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.

Cognitive behavioral therapy for insomnia (CBTI) delivered during pregnancy significantly reduces postpartum depressive symptoms in mothers, new research from UBC shows.

Australian teenagers experiencing increased levels of psychological distress and high social media use are more likely to sleep less than the recommended amount, according to a new study.

Although there has been a slight downward trend in the prescription of benzodiazepines (depressants that relieve anxiety, muscle spasms, produce sedation and reduce seizures) among older adults over the last decade, the rate of first-time prescriptions for these medications after an ischemic (clot-caused) stroke is still sizable, according to research published in Stroke.

A young Israeli researcher who lost a sibling in the Oct. 7, 2023 Hamas attack on Israeli civilians said the tragedy has spurred her to study the unique aspects of grief at the sudden loss of a brother or sister.

A team of biologists, medical researchers and sleep specialists from several institutions in Australia, the U.S. and the U.K. has found that people who regularly experience brighter nights and/or darker days tend to have a higher mortality risk.

Many young adults in Puerto Rico may have less-than-ideal cardiovascular health due to lifestyle behaviors that could increase their risk of heart disease and stroke later in life, new research suggests.

A new diagnosis of Alzheimer's or other dementia often spurs a person to move from their home, new research shows.

Folks who want solid protection during the cold and flu season should get the influenza vaccine now, the U.S. Food and Drug Administration says.

New research has revealed that the connection between per- and polyfluoroalkyl substances, or PFAS, and kidney damage may be tied to dysregulation of the gut microbiome, which is made up of bacteria and other microorganisms that live in the digestive tract.

When trying to understand how genetic influences factor into youth behavior, researchers at Washington University in St. Louis have taken the "big trawl" approach, casting their net wide to pull in all the measured traits, behaviors and environments that make up who we are and examine associations with the genetic building blocks comprising risk for mental health problems.

The FDA recently declined to approve MDMA-assisted therapy for PTSD, but experts said there are many other treatments on the horizon.

A recent breakthrough study has introduced a novel methodology that significantly enhances the accuracy of epidemiological estimates for infectious diseases like COVID-19.

Romania will be one of ten Central and Eastern European countries benefiting from a new initiative that aims to build capacities for more comprehensive cancer care.

The patient was in his 60s, an African American man with emphysema. The oximeter placed on his fingertip registered well above the 88% blood oxygen saturation level that signals an urgent risk of organ failure and death.

Drug overdose deaths dropped a record amount during the past year, according to provisional data the Centers for Disease Control and Prevention.

As the nation searches for ways to reduce the number of young people diagnosed with type 2 diabetes, a new prevention pathway is emerging: Avoiding COVID-19.

Researchers at the German Primate Center—Leibniz Institute for Primate Research in Göttingen have developed a novel training protocol for brain-computer interfaces in a study with rhesus monkeys. The method enables precise control of prosthetic hands using signals from the brain alone.

Do you really know what you look like on the inside? Most people do not, and usually it takes surgery or medical imaging to take a look while we are still alive.

The availability of such kidney transplants outside of the research setting could substantially improve organ availability for patients with HIV.

Twice a month, a 40-foot-long truck transformed into a mobile clinic travels the Rio Grande Valley to provide rural Texans with women’s healthcare, including birth control.

A Texas dairy herd first reported in March that cattle had tested positive for highly pathogenic avian influenza (HPAI). Since then, the H5N1 version of the virus has spread to 299 dairy herds in 14 states, according to the Centers for Disease Control and Prevention, which has also reported more than 100 million poultry affected in 48 states. Twenty cases, all of them non-fatal, have been reported

What scares you the most? Maybe it's teetering precariously on the ledge of a skyscraper; perhaps it's a giant, hairy tarantula crawling across your laptop keyboard. Maybe it's giving a wedding toast and telling a joke that makes nobody laugh.

Picture this: You're shopping online for this week's groceries. You try to pick healthy options based on the information provided by the online retailer. You can tell that the products you're choosing are organic, non-GMO, or Fair Trade Certified. But in many cases, you can't find the nutrition facts, ingredient list, or even a list of allergens.

The rate of laypeople giving naloxone to those who were overdosing increased over a 2-year period but was still small compared with EMS-administered use of the reversal drug, according to a new study.

Patients with neovascular age-related macular degeneration diagnosed by a primary care clinician may be more likely to miss anti-VEGF treatments.

A new serum containing 2-mercaptonicotinoyl glycine as its main ingredient was at least as good as cysteamine 5% cream in treating facial melasma in a randomized study.

In a prospective cohort study, in utero exposure to COVID-19 was not associated with abnormal neurodevelopment in children up to 2 years of age.

The Madrid regional government on Thursday cancelled the traditional annual herding of flocks of sheep through the centre of the Spanish capital scheduled for Sunday as a...

The Global Polio Eradication Initiative (GPEI) needs more funds and has pushed back by three years its target to officially wipe out all forms of the disease, officials said...

Two articles by University of Otago, Christchurch, researchers in this week's New Zealand Medical Journal (NZMJ) raise concerns about global and local readiness to deal with a future pandemic—with one saying we risk falling into "a cycle of panic and neglect" and the other exposing self-reported gaps in health worker preparedness.

MASLD in pediatric obesity was linked to an increased risk for youth-onset type 2 diabetes, especially in the presence of intermediate hyperglycemia.

Glioblastoma is the most common and aggressive type of primary brain tumor, with an average survival rate of 15 months, according to the Centers for Disease Control and Prevention. While glioblastoma can be diagnosed at any age, it's primarily diagnosed in older adults who are an average age of 65 years, according to the National Brain Tumor Society.

The HLA-DRB1*01:03 allele was significantly associated with increased severity of ulcerative colitis, including higher rates of hospitalization, surgery, and corticosteroid use.

Most children develop arches in their feet by early adolescence. About 20 percent, however, have pes planovalgus (PPV), also known as flexible flatfoot.

A new study in Preventive Medicine highlights immigration status as an important social determinant of health in Spain.

In patients with COPD both with or without heart failure, AF episodes rise around the time patients are hospitalized for exacerbations, according to a study of medical device data.

Blocking the sympathetic and parasympathetic pathways led to improved visceral pain and other symptoms following laparoscopic sleeve gastrectomy, new research found.

When Canada legalized recreational cannabis use on Oct. 17, 2018, there were concerns about the potential impacts. Would it trigger greater cannabis use, boost economic growth or otherwise affect the country's health, safety and finances?

Researchers investigated whether induction chemotherapy improves PFS and OS in patients with locally advanced cervical cancer.

Hay fever (or allergic rhinitis) is a long-term inflammatory condition that's incredibly common. It affects about one-quarter of Australians.

Underdiagnosed and undertreated, PMMD comes with high personal and economic costs.

Experimental genetic therapies may soon move forward from preclinical phases.

A first-in-class anti-CD19 B-cell depleting agent was safe and demonstrated superior efficacy vs placebo in patients with generalized myasthenia gravis.

JAK inhibitors were found to be either marginally more effective or as effective as biologic DMARDs in reducing pain in patients with rheumatoid arthritis in clinical practice.

A diet high in ultraprocessed foods can raise the relapse risk in patients with Crohn’s disease who are in remission, with some subgroups of those foods increasing that risk approximately threefold.

From turning study notes into song lyrics to focusing in the OR, healthcare professionals are tapping into the power of music to make themselves better at everything.

Among patients with ischemic stroke, women were found less likely than men to receive and adhere to guideline-directed management therapies, a real-world study found.

Adolescents with type 2 diabetes have a higher incidence of complications than adults with type 2 diabetes or adolescents with type 1 diabetes.

For patients with stage III or IV Hodgkin lymphoma, nivolumab with doxorubicin, vinblastine, and dacarbazine (N+AVD) yields longer progression-free survival (PFS) than brentuximab vedotin with doxorubicin, vinblastine, and dacarbazine (BV+AVD), according to a study published online Oct. 16 in the New England Journal of Medicine.Alex

SAVANNAH, Ga. -- Investigational nipocalimab lessened disease severity in generalized myasthenia gravis (gMG), the phase III Vivacity-MG3 trial showed. The primary endpoint was the change in Myasthenia Gravis Activities of...

In metastatic hormone-sensitive prostate cancer (mHSPC), adding the radioligand 177Lu-PSMA-617 (Pluvicto) to androgen deprivation therapy (ADT) and chemotherapy more than doubled biochemical recurrence-free survival (BRFS), the...

Legislators who want to see an extension of COVID-era telemedicine flexibilities slammed a draft proposed rule from the Drug Enforcement Administration (DEA) that would curb telemedicine prescribing of controlled substances...

For Medicare patients, surgical outcomes were similar whether they had an MD or a DO surgeon, a claims analysis suggested. After adjusting for patient factors and practice settings, there was no difference in the primary outcome...

Ultraprocessed food (UPF) intake accounts for nearly half of toddlers’ energy and increases in mid-childhood, according to a study published online Oct. 4 in the&nbsp;European Journal of Nutrition.Rana E. Conway, Ph.D., from University College London, and colleagues used data from children in the U.K. Gemini twin cohort at 21 months

Maternal hidradenitis suppurativa (HS) was associated with complications during pregnancy as well as long-term maternal and child morbidity, a longitudinal cohort study from Canada showed. In the peripartum period, women with...

From 1999 to 2019, there was a decrease in the sepsis-related mortality rate (SRMR) in children overall and across demographic groups, according to findings presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in Los Angeles.Ladonna Boasiako, M.D., M.P.H., from Brandywine, Maryland, a

Adding nivolumab (Opdivo) instead of brentuximab vedotin (Adcetris) to the standard chemotherapy backbone of doxorubicin (Adriamycin), vinblastine, and dacarbazine (AVD) resulted in longer progression-free survival (PFS) in adolescents...

Kidney transplantation from donors with HIV appeared to be noninferior to donors without HIV in terms of safety for recipients with HIV, an observational study indicated. Among 198 patients with HIV who received a kidney from...

Individuals with multiple long-term conditions are two and a half times more likely to die following COVID-19 infection than others. When children were assessed separately, the risk for mortality among those with multiple long-term conditions increased to almost three times (2.8) the risk of those without. The mortality rates are 22% and 8% respectively.

No individual antipsychotic was associated with better cognitive outcomes than placebo in patients with schizophrenia spectrum disorders (SSD), according to a systematic review and network meta-analysis. However, the study revealed...

In a study of commonly used treatments for people with multiple sclerosis, both medical and behavioral interventions, and a combination of the two, resulted in meaningful improvements in fatigue, a University of Michigan-led study finds.

Over 200 leading doctors, professional bodies and charities are urging the chancellor to use the budget on 30 October to invest in creating a smoke free UK as quickly as possible, and make the tobacco industry pay.

Potential fathers with type 2 diabetes can be reassured that taking the drug metformin is not associated with birth defects in their offspring, concludes a large study of more than 3 million pregnancies published by The BMJ.

If you're like most Americans, you prefer to be paid electronically instead of with old-fashioned paper checks. But imagine if your employer forced you to pay a 2% to 5% processing fee out of each paycheck just for the convenience...

One of the misconceptions about food allergies during air travel is that aerosolized nut particles circulate in the aircraft ventilation system and pose a significant risk, which could be mitigated by "nut bans," according to...

In 2023, an estimated 15.5 million U.S. adults had an attention deficit-hyperactivity disorder (ADHD) diagnosis; half were diagnosed in adulthood. (Morbidity and Mortality Weekly Report) And 25% of adults suspect they may have...

Patients with inflammatory bowel disease (IBD) who initially responded to the investigational monoclonal antibody tulisokibart continued to maintain clinical and endoscopic improvements through week 50, according to data from...

The Tobacco Control and Governance team of the Ateneo Policy Center recently published a paper titled "An analysis of flavor descriptors on tobacco products in the Philippines: Regulatory implications and lessons for low- and middle-income countries" in the journal Globalization and Health.

Men with localized prostate cancer were randomly assigned to receive either SBRT or control radiotherapy in a phase 3 trial.

Nager syndrome, or NS, is a rare genetic disease that affects the development of the face and limbs, usually causing anomalies in the bone structures of the jaws, cheeks, and hands. With a prevalence of less than 100 cases ever reported, not much is known about the disease except the fact that mutations in the SF3B4 gene are its primary cause.

It is just as safe and effective for people with HIV in need of kidney transplantation to get their organ from donors who are also HIV positive as it is from donors who are not infected with the virus, a new study shows. Survival rates for organ recipients one and three years after the procedure were the same for donors with or without HIV. Also, risks of serious side effects, such as infection, f

A treatment that rallies the immune system to destroy cancer raised the survival rate for advanced Hodgkin lymphoma patients to a remarkable 92%, suggesting a new standard therapy for the disease. The New England Journal of Medicine published the innovative clinical trial results.

A new Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2 infections can trigger immune responses in a pregnant individual that may cause serious inflammatory responses in the developing fetus.

The U.S. Food and Drug Administration has approved Itovebi (inavolisib), in combination with palbociclib (Ibrance) and fulvestrant, for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer.

Researchers at Rutgers University-New Brunswick, along with international collaborators, have introduced a novel method for identifying the crucial set of gut microbes commonly found in humans and essential for health.

Patients aged 10 to 17 years who are prescribed glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are more likely to have comorbid type 2 diabetes, high body mass index, and a previous metformin prescription, according to a research letter published online Oct. 16 in JAMA Network Open.

For the first time, researchers have used blood tests to identify concussion caused by intimate partner violence (IPV) in patients, including some that also experienced non-fatal strangulation.

An international team of researchers has identified new drug targets for therapies that could benefit patients with different forms of retinitis pigmentosa and other inherited retinal diseases. Using advanced proteomics techniques, they unveiled shared critical pathways in retinitis pigmentosa disease models.

Researchers have identified the origin of ovarian cancer that develops in the fallopian tube, which opens doors to discovering new methods for diagnosing the disease and potential therapies.

During the COVID-19 public health emergency (PHE) period, excess mortality occurred in all racial and ethnic groups, but disparities were observed, according to a study published online Oct. 11 in JAMA Network Open.

Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. Physician Befriended Captive Saudi Princess After years of working for the Saudi royal family...

A study led by Dr. Hassan Aboul-Ella (Department of Microbiology, Faculty of Veterinary Medicine, Cairo University) has been published in the journal Molecular Biomedicine.

There is an imbalance in the gut flora of patients with epilepsy compared with healthy controls, according to a study published online Sept. 28 in the Journal of Health, Population and Nutrition.

One of the main physical symptoms of alcohol withdrawal is "allodynia"— increased sensitivity to mechanical stimuli that are normally innocuous, which is a clinical sign of chronic pain.

Biologists at Brown University have discovered how a neuropeptide hormone made in the gut of flies can control their lifespan.

Recently, Prof. Huang Qing's group from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences studied the new functions of ganoderic acids. They discovered that a compound, ganoderic acid A (GAA), could help fight cancer by targeting glucose transporters, proteins that cancer cells use to take in sugar.

I was very touched when my rabbi asked me to give a 10-minute presentation on the night before Yom Kippur -- the holiest night on the Jewish calendar. The rabbi's invitation was very specific in that during this year's "High...

Understanding in depth how tumors evolve to become malignant is the objective of a study recently published in the journal Nature Cancer. The findings demonstrate that within each tumor, groups of cells receive instructions to spread malignantly throughout the body. Other groups of cells are responsible for combating the damage caused by the cancerous tumor.

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity.

The authors of a new article in Journal of Palliative Medicine state that the "growing role of the financial sector in home health and hospice, a reflection of larger trends in U.S. health care, is concerning and has major implications for care quality unless reforms are undertaken."

For people with ischemic stroke, treatment with the clot-busting drug tenecteplase is associated with a slightly higher likelihood of an excellent recovery and reduced disability three months later than the drug alteplase, according to a meta-analysis published in the October 16, 2024, online issue of Neurology. Researchers found that the likelihood of good recovery was similar between the two tre

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

TORONTO -- A homeless man refusing long-term care, a woman with severe obesity, an injured worker given meager government assistance, and grieving new widows. All of them requested to be killed under Canada's euthanasia system...

A study published in the Journal of Exposure Science & Environmental Epidemiology has found that nearly all pregnant women ingest the fungal toxin zearalenone (ZEN), which mimics estrogen in the body and hinders reproduction in some animals.

Some of the lowest-paid healthcare workers in California will get a pay bump Wednesday under a state law gradually increasing their wages to at least $25 an hour. Workers at rural, independent healthcare facilities will start...

Patients aged 10 to 17 years who are prescribed glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are more likely to have comorbid type 2 diabetes, high body mass index, and a previous metformin prescription, according to a research letter published online Oct. 16 in&nbsp;JAMA Network Open.Margaret G. Miller, from Case Western Re

Go to the doctor to provide a blood sample, and you're typically faced with a needle and syringe, and hours or even days of waiting to get results back from a lab. CU Boulder researchers hope to change that with a new handheld, sound-based diagnostic system able to deliver precise results in an hour with a mere finger prick of blood.

COVID-19 vaccination is associated with a reduced risk for most cardiovascular events, but with slightly increased risks of extrasystoles and transient ischemic attack, as well as myocarditis and pericarditis after mRNA vaccination, according to a study published online Sept. 30 in the European Heart Journal.Yiyi Xu, Ph.D., from the

For nearly a decade, Brown University researcher Diane Hoffman-Kim and her laboratory team have made cortical spheroids, which are basically functional miniature brains. The three-dimensional cell cultures are versatile models that allow for the study of everything from brain injuries to stroke to glioblastoma. Most recently, Hoffman-Kim's team found a way to use the mini-brains to study the effec

The investigational monoclonal antibody nipocalimab is associated with significant improvement in patients with generalized myasthenia gravis phase 3 results suggest.

A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and Massachusetts General Hospital (MGH) demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic granulomatous disease (X-CGD),

The U.S. Food and Drug Administration approved Itovebi (inavolisib), in combination with palbociclib (Ibrance) and fulvestrant, for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer.Th

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

For individuals with heart failure with reduced ejection fraction (HFrEF), substantial mortality benefits would result from optimal use of guideline-directed medical therapy (GDMT), according to a study published online Oct. 2 in JAMA Cardiology.Amber B. Tang, M.D., from the University of California Los Angeles, and colleagues examin

During the COVID-19 public health emergency (PHE) period, excess mortality occurred in all racial and ethnic groups, but disparities were observed, according to a study published online Oct. 11 in JAMA Network Open.Jeremy Samuel Faust, M.D., from Mass General Brigham in Boston, and colleagues characterized overall and age-specific al

The International Ovarian Tumour Analysis consortium (IOTA) Assessment of Different Neoplasias in the Adnexa (ADNEX) at 10 percent is more sensitive, but less specific, for diagnosing ovarian cancer compared with Risk of Malignancy 1 (RMI1) at 250, according to a study published in the October issue of The Lancet Oncology.Sudha Sunda

A modified insulin that can prevent sudden drops in blood sugar has been demonstrated in laboratory experiments and animal models, reports a paper in Nature. This could provide a more flexible way to supplement insulin for individuals with diabetes and reduce sudden drops in blood glucose.

The rate of layperson-administered naloxone (LAN) increased from 2020 to 2022, according to a study published online Oct. 14 in&nbsp;JAMA Network Open.Christopher B. Gage, from Ohio State University in Columbus, and colleagues assessed whether the frequency of LAN in conjunction with emergency medical services (EMS) activations chang

Asian patients are half as likely to be started on biologic drugs for rheumatoid arthritis as white patients, new research has shown.

The risk of cholera spreading in Lebanon is "very high", the World Health Organization warned Wednesday, after a case of the acute and potentially deadly diarrheal infection was detected in the conflict-hit country.

In this Instagram Live clip, MedPage Today editor-in-chief Jeremy Faust, MD, and Lawrence Gostin, JD, director of the O'Neill Institute at Georgetown University in Washington, discuss how the Supreme Court has limited the powers...

The risk for an incident diagnosis of type 2 diabetes (T2D) is increased in the six months following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, according to a study published online Oct. 14 in JAMA Network Open.Margaret G. Miller, from the Case Western Reserve University School of Medicine in Cleveland, a

has shown that this type of MRI signal was increased in regions of the midbrain in young adults ages 20 to 24 who had an extensive alcohol and drug use history.

Unimaginable pain and restlessness. Vomiting so frequent and forceful that it can perforate the esophagus. Blood pressure and heart rate so high that they damage the heart. Sweating that drenches clothing and sheets. Nerve sensitivity that makes even the softest touch agonizing. A prolonged panic attack that is provoked and worsened by even mundane activities and conversations.

The chemical messenger dopamine is an essential catalyst that fuels activities and behaviors ranging from movement to cognition and learning. However, neuroscientists have long debated whether these functions rely on rapid bursts of dopamine or on the neurochemical's slower action.