A nationwide, couple-based reproductive carrier screening program has demonstrated feasibility in informing reproductive decision-making, according to a study published in the Nov. 21 issue of the New England Journal of Medicine.Edwin P. Kirk, M.B., B.S., Ph.D., from the Sydney Children's Hospital, and colleagues examined the feasibi

About 6 in 10 people say they probably won’t get an updated shot this year, despite the CDC’s recommendation that everyone do so.

Among older individuals with overweight, vitamin D supplementation coadministered with calcium reduces systolic and diastolic blood pressure (SBP and DBP), according to a study published online Nov. 12 in the Journal of the Endocrine Society.Maya Rahme, from the American University of Beirut Medical Center, and colleagues examined th

Adults with nonarteritic anterior ischemic optic neuropathy have an increased risk for stroke over 10 years follow-up and could benefit from regular monitoring.

A number of adults with outpatient medically attended respiratory syncytial virus (MA-RSV) infection experience hospitalization within 28 days, with a higher proportion among high-risk subgroups, according to a study published online Nov. 19 in JAMA Network Open.Suzanne N. Landi, Ph.D., M.P.H., from Pfizer Inc. in New York City, and

Disparities exist in telemedicine utilization for neurologic conditions, according to a study published online Nov. 20 in Neurology: Clinical Practice.Marisa Patryce McGinley, D.O., from the Cleveland Clinic, and colleagues characterized outpatient telemedicine utilization for neurologic conditions and identified potential disparitie

Higher consumption of ultraprocessed foods, such as carbonated drinks, processed meats, and sweet or savory packaged snacks, is associated with accelerated biological aging.

WASHINGTON -- Health transparency rules have helped researchers gain more insight into hospital pricing practices, Ge Bai, PhD, CPA, said here Wednesday at an event sponsored by Georgetown University's Center on Health Insurance...

Couples who were found to be genetic carriers for autosomal recessive or X-linked genetic conditions often opted to change their reproductive strategy, a large Australian population-based study found. Overall, 1.9% of the 9...

Sodium oxybate (Xyrem), a drug approved to treat people with narcolepsy, provided temporary relief for laryngeal dystonia patients whose symptoms were alcohol-responsive, a phase IIb, double-blind, crossover trial showed. The...

Semaglutide (Wegovy) improved liver fibrosis in patients with metabolic dysfunction-associated steatohepatitis (MASH) and led to greater rates of MASH resolution, an interim analysis of a phase III trial showed. In part 1 of...

In less than a month, Texas Attorney General Ken Paxton has sued three doctors who provide gender-affirming care to minors in an attempt to enforce a state law that bans such care. The first lawsuit, filed October 17, alleged...

An international expert consensus statement provided best-practice recommendations for the off-label use of low-dose oral minoxidil among patients with hair loss. Using a modified Delphi process, 43 hair-loss specialist dermatologists...

WASHINGTON -- A small implant delivering electrical stimulation to the vagus nerve outperformed a sham treatment in relieving rheumatoid arthritis (RA) symptoms among patients who failed at least one biologic or targeted synthetic...

A Dallas anesthesiologist was sentenced Wednesday to 190 years in prison for injecting a nerve-blocking agent and other drugs into bags of intravenous fluid at a surgical center where he worked, leading to the death of a coworker...

The Department of Justice launched an investigation into whether adults with serious mental illness were unnecessarily institutionalized in Michigan state-run psychiatric hospitals. (CBS News) In a phase II trial of major depressive...

Tapering doses of corticosteroids was safer than, and just as effective as, a fixed dose in patients with severe alcohol-associated hepatitis, a randomized trial showed. Patients who received a tapered dose of prednisolone starting...

Since the modern practice of anesthesia has evolved, providers have been concerned about pulmonary aspiration -- when gastric contents enter the lung, resulting in severe complications including pneumonitis, and aspiration...

EPWORTH, Zimbabwe -- Carrying her infant daughter, 19-year-old Sithulisiwe Moyo waited 2 hours to get birth control pills from a tent pitched in a poor settlement on the outskirts of Zimbabwe's capital, Harare. The outreach...

Diagnoses of postpartum depression (PPD) increased significantly across all racial and ethnic groups and prepregnancy body mass index (BMI) categories over the past decade, according to a California-based cross-sectional study...

In 3-year data from the CAPELLA study, the subcutaneous, long-acting capsid inhibitor lenacapavir (Sunlenca) demonstrated sustained suppression with no emergence of resistance in highly treatment-experienced individuals with...

Jay Bhattacharya, MD, PhD, of Stanford University in California, has emerged as President-elect Donald Trump's top pick to lead the National Institutes of Health (NIH), according to reporting from the Washington Post. Amid Trump...

CHICAGO -- Metformin with or without lifestyle modification did not reduce daily atrial fibrillation (Afib) burden over standard of care for patients with implanted heart devices, the randomized TRIM-AF trial showed. In fact...

The experts interviewed for this article are Sanofi's paid partners. Respiratory syncytial virus (RSV) lower respiratory tract infections are particularly concerning in infants due to their potential to cause severe respiratory...

Up to 15% of all couples suffer from infertility at some point in their lives. Lack of knowledge about the causes of fertility problems can lead to prolonged clinical testing and extended treatment periods.

Researchers at Germans Trias i Pujol Research Institute (IGTP) and Institut d'Investigació Sanitària Pere Virgili (IISPV) have conducted a review on the therapeutic potential of extracellular vesicles in inflammatory bowel disease. While this approach remains in the early stages of research, ongoing clinical studies for various diseases already support its viability.

The UPV/EHU's Nursing and Health Promotion research group compared seven nutrition labeling schemes in Europe, Oceania and South America and found that they barely coincide when specifying whether cooked foods are healthy. So the researchers concluded that a new system for assessing the food quality of ready meals needs to be developed.

A recent study has uncovered the intricate ways in which a rare genetic mutation impacts brain cell communication, providing critical insights into the causes of a severe neurological disorder known as developmental and epileptic encephalopathy (DEE). The findings reveal that this specific mutation in a regulatory calcium channel subunit disrupts both the calcium handling and structural connection

The prevalence of suicide is higher among those with epilepsy compared with the general population, according to a study published in the journal Epilepsy & Behavior.

Spinal cord stimulation (SCS) for treatment of chronic pain in the back and/or lower extremities is associated with greater improvements in pain compared with conventional medical management (CMM), according to a review published online Nov. 14 in JAMA Network Open.

The prevalence of high total cholesterol was 11.3% among U.S. adults from August 2021 to August 2023, according to a November data brief published by the National Center for Health Statistics.

Rates of postpartum depression have more than doubled in little over a decade among American women, a new analysis shows.

A dramatic, threefold reduction in repeat operations in patients surgically treated for chronic subdural hematoma was achieved when the artery supplying the brain covering was blocked, according to results of a national clinical trial led by neurosurgeons at the University at Buffalo and Weill Cornell Medicine published in the New England Journal of Medicine.

There are bidirectional associations for sleep disorders with chronic kidney disease (CKD), according to a review published in the November issue of Chronic Kidney Journal.

A child in California has tested positive for bird flu, despite having no known contact with infected animals, state officials reported Tuesday.

CHICAGO -- Treatment with the potassium binder sodium zirconium cyclosilicate (SZC; Lokelma) stabilized potassium levels among patients with heart failure with reduced ejection fraction (HFrEF) during spironolactone optimization...

For patients with atrial fibrillation who need protection from stroke and other complications after ablation, left atrial appendage closure rivaled oral anticoagulation in a randomized trial.

Welcome to the latest edition of Investigative Roundup, highlighting some of the best investigative reporting on healthcare each week. What It's Like to Win an Ig Nobel While Ig Nobel honorees aren't always sure they want the...

Friends tend to share common interests, tastes, lifestyles, and other traits, but a new Yale-led study demonstrates that similarities among buddies can also include the makeup of the microbes lining their guts.

Researchers at the University of Virginia have made a significant discovery that could change how doctors treat viral infections of the heart. The study, published in Science Advances, reveals that the heart responds to viral infections in one of three distinct ways, offering new insights that may lead to better treatments for people at risk of heart failure. These findings bring new hope for pati

CHICAGO -- Sacubitril/valsartan (Entresto) was effective at keeping cardiotoxicity at bay in high-risk people receiving anthracycline chemotherapy in the SARAH trial. Cancer patients were less likely to have a greater than...

The prevalence of high total cholesterol was 11.3 percent among U.S. adults in August 2021 to August 2023, according to a November data brief published by the National Center for Health Statistics.Margaret D. Carroll, M.S.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues presented the prevalence of

High cardiorespiratory fitness (CRF) is associated with better cognitive performance and lower dementia risk, according to a study published online Nov. 19 in the British Journal of Sports Medicine.Shuqi Wang, from the Tianjin Medical University in China, and colleagues examined the association of CRF with cognitive function and deme

Half of young adult patients treated in emergency departments in three urban hospitals across the country reported experiencing violence either as a victim or aggressor, including firearm violence, in the six months prior to seeking treatment, according to a University of Michigan study.

Young adults at risk of psychosis show reduced brain connectivity, a deficit that cannabis use appears to worsen, a new study has found. The breakthrough paves the way for psychosis treatments targeting symptoms that current medications miss.

Recovery from an autoimmune inflammation of the brain may take three years or more, according to a study published in the November 20, 2024, online issue of Neurology.

For people seeing a neurologist, their age, race, ethnicity and neighborhood may play a role in whether they do so in person or virtually, via telemedicine, according to a study published in Neurology Clinical Practice. These results do not prove these factors increase or decrease a person's likelihood to choose telemedicine, they only show an association.

Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of newborn mortality and morbidity worldwide, and lowering the baby's body temperature—called therapeutic hypothermia—is often used as a treatment.

In pregnant women, the oral microbiome is associated with stress and mental health, according to a study published online Nov. 19 in BMJ Mental Health.Ann M. Alex, Ph.D., from Michigan State University in East Lansing, and colleagues explored a potential oral-brain-behavior axis related to maternal mental health using saliva samples

Spinal cord stimulation (SCS) for treatment of chronic pain in the back and/or lower extremities is associated with greater improvements in pain compared with conventional medical management (CMM), according to a review published online Nov. 14 in JAMA Network Open.Frank J. P. M. Huygen, Ph.D., M.D., from Erasmus Medical Center in Ro

For patients with type 2 diabetes and elevated systolic blood pressure, an intensive-treatment strategy is better than a standard-treatment strategy for incidence of major cardiovascular disease events, according to a study published online Nov. 16 in the New England Journal of Medicine to coincide with the American Heart Association Scient

Teledermoscopy has high accuracy for detecting skin cancers, according to a research letter published online Nov. 9 in the Journal of the American Academy of Dermatology.Jenne P. Ingrassia, from New York Medical College in Valhalla, and colleagues conducted a prospective diagnostic accuracy study to compare the accuracy of telemedici

There are bidirectional associations for sleep disorders with chronic kidney disease (CKD), according to a review published in the November issue of Chronic Kidney Journal.Jin Hean Koh, from the National University of Singapore, and colleagues examined the bidirectional association between sleep disorders and CKD in a systematic revi

Females sleep less, wake up more often and get less restorative sleep than males, according to a new animal study by University of Colorado Boulder researchers.

Until now, COVID vaccines have been available to pregnant women as part of the twice-yearly booster program, but this offer is being withdrawn.

According to a new study from researchers at Wake Forest University School of Medicine and The Hospital for Sick Children (SickKids) in Toronto, being born preterm is associated with an increased risk of death from birth until the third and fourth decades of life.

The prevalence of suicide is higher among those with epilepsy compared with the general population, according to a study published in the December issue of Epilepsy & Behavior.Sara Melin, from the Karolinska Institutet in Stockholm, and colleagues examined the incidence of suicide for people with epilepsy in Sweden and compared i

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

The combination of common DNA differences can help explain why some people have a rare neurodevelopmental brain condition without a specific, single genetic mutation causing it.

Loughborough University researchers have developed an artificial intelligence (AI) tool that identifies the key human factors influencing maternity care outcomes, supporting ongoing efforts to improve safety for mothers and babies.

A surge of calls to the 988 Suicide and Crisis Lifeline one year after the Lahaina wildfires underscores urgent need for expanded Hawaiʻi-based mental health support services. However, limited local resources have caused many calls to be rerouted to out-of-state services, exposing critical gaps in local mental health infrastructure. These findings were published in JAMA Network Open on November 20

Diabetes develops when the body fails to manage its blood glucose levels. One form of diabetes causes the body to not respond to insulin at all. Called Type 1 diabetes, or T1D, this autoimmune disease happens when the body's defense system mistakes its own insulin-producing cells as foreign and kills them. On average, T1D can lead patients to lose an average of 32 years of healthy life.

Incidence of stroke and ischemic heart disease are declining around the world, except for in a handful of regions, according to research in PLOS Global Public Health. Wanghong Xu of Fudan University and colleagues find that in East and West Sub-Saharan Africa, East and Central Asia and Oceania, ischemic heart disease is increasing, which may be attributed to eight factors that include diet, high B

Microscopic, single-cell differences found in the lungs of COVID-19 patients in Malawi demonstrate the value and importance of cutting-edge infectious disease research in Sub-Saharan Africa.

A new approach to analyzing brain scans could help researchers better understand psychiatric illness using much smaller groups of patients than previously thought necessary, potentially accelerating the development of more precise mental health treatments.

Hair loss significantly impacts patients' quality of life, and it may be nonscarring or scarring. Etiologically, hair loss may be hereditary (androgenetic alopecia [AGA]); related to age; congenital (hair shaft disorders); traction-induced; inflammatory (primary scarring alopecia); autoimmune (alopecia areata); or secondary to medical, surgical, or emotional stressors (telogen effluvium), infectio

A study from Tel Aviv University expands the understanding of the biological mechanism underlying genetically-based autism, specifically mutations in the SHANK3 gene, responsible for nearly one million cases of autism worldwide. Based on these discoveries, the research team applied a genetic treatment that improved the function of cells affected by the mutation, laying a foundation for future trea

Fibromyalgia is a chronic disorder characterized by muscle pain throughout the body, fatigue, sleep problems and cognitive difficulties. The condition predominantly affects women, but men can also suffer from it. However, they often do so in silence, as they face cultural, medical and psychological barriers to being taken seriously and receiving treatment.

Two FDA panels were almost unanimous in their opinion that the agency should eliminate restrictions that psychiatrists and patients say limit access to clozapine.

A research team behind a new study at the Hebrew University of Jerusalem has made an important breakthrough in understanding how immune cells known as T cells are activated.

A new study by researchers at the University of Galway and the University of Limerick suggests that electrical stimulation might be essential for tendons to maintain their health, offering fresh possibilities in tendon repair and regeneration.

Patients with symptomatic anemia associated with chronic kidney disease who are on chronic maintenance dialysis can now also receive vadadustat instead of an erythropoiesis-stimulating agent such as darbepoetin.

Researchers at Duke University School of Medicine have found that tapping into the nervous system could help reduce the gut inflammation that drives inflammatory bowel disease (IBD).

Most adults in the U.S. get less sleep than recommended across the board, and some racial and ethnic groups fare even worse, according to a new study that used readings from thousands of people who wore commercially available fitness trackers that monitored their sleep.

The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions such as celiac disease, ulcerative colitis, and Crohn's disease. Scientists don't fully understand how different regions of the organ resist or adapt to changes in the enviro

Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study in JACC: Basic to Translational Science. The authors say the research should serve as a "cautionary tale" about possible long-term health effects of these drugs.

Drug-drug interaction (DDI) is a phenomenon in which the efficacy of a drug is weakened or enhanced when multiple drugs are combined. The DI can cause serious health risks to patients.

A joint FDA advisory committee on Tuesday overwhelming voted to eliminate the risk evaluation and mitigation strategy (REMS) program designed around the risk for severe neutropenia associated with clozapine, a drug used to treat...

Note that some links may require registration or subscription. Endocrinologist Olga Duchon, MD, was fatally shot over the weekend in suburban Chicago less than 2 hours after giving a talk on weight-loss medications. Police say...

A new pathology tool created at Yale harnesses barcode technology and shows potential for use in cancer diagnoses. The technology, Patho-DBiT (pathology-compatible deterministic barcoding in tissue), was discussed in a new study published in the journal Cell.

People with chronic liver disease can be categorized into four distinct risk groups based on the different barriers they face in obtaining outpatient care, barriers that increase their odds of requiring hospitalization, a new UCLA study finds.

Educational achievement, mental health diagnoses, childhood abuse, number of arrests and number of children all play a complex role in shaping a person's vulnerability to commercial sexual exploitation, how long they are exploited for and how difficult it is to get out. That is one conclusion of a study published November 20, 2024 in PLOS ONE by Courtney Furlong and Ben Hinnant of Auburn Universit

Periods can feel like an unwanted guest for many women and gender-diverse people who menstruate, bringing cramps, mood swings and exhaustion.

Doctors have long known that lead exposure during pregnancy poses significant health risks for both mothers and newborns, but universal screening is not mandated in New Jersey or nationwide.

Gastroenterologists who focus primarily on providing inpatient care, called GI Hospitalists, are becoming more common across the U.S. Researchers at Brigham and Women's Hospital developed a survey to assess the effect of GI Hospitalists on fellowship education and found that GI Hospitalists improve education through superior endoscopy teaching and longitudinal feedback.

Disruptions to support services during the COVID-19 pandemic led Australians with disabilities to report significant declines in life satisfaction and mental health, a new study from Flinders University has found.

Researchers are hunkering down to develop tools that can better predict suicide and prevent deaths. Data mining and a multidisciplinary approach are key.

Historical policies shaping educational attainment have enduring benefits for later life memory and risk of dementia, according to a study led by a Rutgers Health researcher.

The development marks the fifth approved indication of the drug since October 2023.

A child in California has tested positive for bird flu, despite having no known contact with infected animals, state officials reported Tuesday."California has identified a possible bird flu case in a child in Alameda County who was tested for mild upper respiratory symptoms. The child, who ha

PET imaging using a radiolabeled antibody picked up clear cell renal cell carcinoma and could help avert unnecessary biopsies and surgeries.

A new technology that allows doctors to quantify blood flow in the heart can improve their ability to diagnose potentially deadly coronary artery disease (CAD), an international study led by School of Medicine investigators has found.

Health centers across Japan conduct simple physical performance tests for older adults, including the single-leg balance and sit-to-stand tests. Based on a follow-up study of approximately 1,000 individuals, researchers at University of Tsukuba have developed an evaluation scale that uses the combined scores of three simple physical performance tests to predict high risk of requiring long-term car

In April, just 12 weeks into her pregnancy, Kathleen Clark was standing at the receptionist window of her OB-GYN's office when she was asked to pay $960, the total the office estimated she would owe after she delivered.

A study published today in Gastroenterology provides the most comprehensive assessment to date of pediatric inflammatory bowel disease (IBD) prevalence in the United States.

As populations age, the prevalence of sarcopenia—a progressive loss of muscle mass and function—has become an increasingly urgent public health concern. Sarcopenia increases the risk of falls and frailty, reduces the quality of life for older adults, and heightens the likelihood of requiring long-term care. Preventing sarcopenia is, therefore, crucial for alleviating this health care burden.

The World Health Organization has authorized the first mpox vaccine for children, a decision experts hope will help make immunizations more widely available to one of the hardest-hit populations during the ongoing outbreaks of the disease in Congo and elsewhere in Africa.

UK claimants Wednesday announced legal action against US pharmaceutical and cosmetics giant Johnson & Johnson, alleging that women diagnosed with cancers were exposed to asbestos in the company's talcum powder.

We live longer and longer, and as we age, a lot of us develop a series of health issues and chronic diseases, including chronic obstructive pulmonary disease (COPD), which is found in around 600 million individuals globally. However, only half of them know they have the disease.

Depression is one of the most common mental illnesses. As many as 280 million people worldwide are affected by this disease, which is why researchers at Kaunas University of Technology (KTU) have developed an artificial intelligence (AI) model that helps to identify depression based on both speech and brain neural activity.

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

Although the United States has made significant headway in curbing cigarette smoking and secondhand smoke exposure, a new report finds deep divisions remain and they run along predictable fault lines.Disparities in tobacco use continue to persist by income and occupation, geography, education, race and ethnicity, sexual orientation and gender

Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year—most of them African children under five.

Children living in war-torn countries not only suffer from poor mental health outcomes, but war may cause adverse biological changes at the DNA level, which could have lifelong health impacts, according to a study from the University of Surrey.

Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School and Memorial Sloan Kettering Cancer Center (MSK) have pinpointed what could be the early genetic origins of breast cancer—cancer-like mutations appearing in the cells of healthy women.

Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.

Immunotherapy is a promising treatment that recruits the immune system to help fight cancer, but it has had limited success in gastrointestinal cancers. Now, researchers at Washington University School of Medicine in St. Louis have engineered a probiotic that delivers immunotherapy directly to the gut to shrink tumors in mice, offering a potentially promising oral drug for hard-to-reach cancers.

The most comprehensive cell map of the human gut to date has been created by combining spatial and single-cell data from 1.6 million cells.

By creating the first spatial atlas of the developing human thymus, a vital organ that trains immune cells to protect against infections and cancer, scientists have discovered that the foundation for lifelong immunity is established earlier than previously thought.

The first "blueprint" of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer. The discovery could lead to new treatments for inflammatory bowel disease (IBD) and cancer.

President-elect Donald Trump's incoming administration could try to remove fluoride from drinking water, according to Robert F. Kennedy Jr.

The U.S. Preventive Services Task Force (USPSTF) recommends early screening for syphilis infection in all pregnant women (grade A recommendation). This recommendation forms the basis of a draft recommendation statement published online Nov. 19.

The United States has reported its first confirmed case of the more contagious form of mpox, formerly known as monkeypox.

For patients with chronic kidney disease (CKD), the risk for emergently treated hypocalcemia with denosumab increases with worsening CKD stage, according to a study published online Nov. 19 in the Annals of Internal Medicine.

Hospitals around the country are conserving critical intravenous fluid supplies to cope with a shortage that may last months. Some hospital administrators say they are changing how they think about IV fluid hydration altogether.

Antiviral treatment is underutilized among children and adolescents hospitalized with influenza, according to research published in the Nov. 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Deep brain stimulation has revealed that a specific type of brain wave activity is associated with levels of anxiety in people living with Parkinson's disease, according to research led by scientists at City St George's and University of California San Francisco.

After the June 2022 US Supreme Court ruling that allowed states to ban abortion, women of childbearing age in states where abortion became illegal reported increased rates of anxiety. That's according to a study published in Contemporary Economic Policy.

Nearly one in every 10 American adults is living with high levels of cholesterol in their arteries, according to the latest report from the U.S. Centers for Disease Control and Prevention.

Cholesterol is a type of fat in our blood. Our bodies need a small amount of cholesterol to build the structure of cell membranes, make certain hormones and help with metabolism, such as producing vitamin D. The catch: We don't need too much cholesterol.

A report released from the National Academies of Sciences, Engineering, and Medicine Health and Medicine Division addresses the responsible use of race and ethnicity in biomedical research and is a call to action for biomedical research to rethink how it uses race and ethnicity.

Researchers have used artificial intelligence (AI) to analyze patient urine samples and predict when symptoms of chronic obstructive pulmonary disease (COPD) will flare up, according to a study published in ERJ Open Research.

Updates to two genetic risk assessment guidelines now include prostate, endometrial, and gastric cancer to reflect the growing understanding of hereditary cancer risk and value of genetic testing.

Transplant rates and waitlist dropouts for women are now similar to those for men, yet some disparities still exist.

Despite regulations, lung screening is lacking for workers, those exposed to shrapnel, or those located near risky sites.

Even though adding HPSA testing to a colon cancer screening program did not reduce the incidence or mortality rates of gastric cancer, potential benefits were still observed.

New data for 2023 showed a decline of approximately 2% across three notifiable infections.

The timing and rate of body weight changes throughout life may predict an individual's likelihood of living to extreme old age.

Sleep-related daytime dysfunction was linked to increased risk for motoric cognitive risk syndrome in older adults.

A one-question screening method could catch hearing loss among many older adults who may otherwise never be asked.

In a cohort study, patients who underwent ultrasonography-guided nerve blocks in the emergency department experienced a complication rate of 0.4%, with one major and nine minor adverse events.

Combining magnetic and direct current transcranial stimulations was more effective than either treatment alone for major depressive disorder.

Thousands of Italian doctors and nurses stayed at home on Wednesday to protest over their pay and conditions in the latest sign of malaise in the country's struggling health...

Only one individual in a high-risk population who received early intervention progressed to an AIDS diagnosis.

Multi-year data spotlight low screening rates in high-risk population.

Advances in cochlear implant technology are making hearing restoration more precise, personal, and accessible to patients of all ages.

Neuroticism is a key personality trait described by well-established psychological theories, associated with a tendency towards emotional instability and negative emotions. Past studies found that this personality trait often goes hand in hand with various mental health disorders, as well as some chronic and severe medical conditions.

Integrated care for dementia patients could reduce hospitalizations and medication risks, according to new research.

A study using a Korean database found that COVID-19 infection raised long-term risks for various autoimmune and autoinflammatory skin disorders, and vaccination may reduce these risks.

Dermatologic adverse events affected 97.8% of pediatric patients on MEK inhibitors, in a small retrospective single-center study.

About 44% of U.S. employers with 500 or more employees cover drugs for weight loss in 2024, up from 41% in 2023, according to a survey from consulting firm Mercer released...

Sedentary time exceeding 10.6 h/d was associated with a higher risk for heart failure and cardiovascular mortality in a new study.

A study reviewed measures to assess burnout and depression among physicians, causal factors, and interventions to improve well-being.

Although not guideline-approved, screening for iron deficiency in patients with risk factors could prevent progression to more severe conditions.

A recent Medscape survey found that work-life balance is the top source of stress for US medical students, and experts are stressing the importance of self-care. Here’s a look at what that might look like.

The World Health Organization’s new toolkit aims to enhance the quality and accessibility of long-term care to enable more responsive, inclusive, and sustainable systems.

Using home spirometry for the management of systemic sclerosis–associated ILD can enhance the ability to detect pulmonary decline early, leading to better patient care and outcomes.

The World Health Organization on Tuesday approved an mpox vaccine from Japanese pharma company KM Biologics for emergency use, the second one to get the agency's seal of approval.

The World Health Organization said on Tuesday in Rio de Janeiro that it had raised nearly $4 billion dollars through a new financing mechanism it launched in May.

Pakistan detected one more polio case in the restive northwest bordering Afghanistan, raising the country's tally of the infectious disease to 50 cases this year, officials said Wednesday.

Early implementation of treatment with biologic or targeted synthetic DMARDs after methotrexate failure did not prevent the development of difficult-to-treat RA in patients with early RA.

A study found that GLP-1 RA use is linked to risks for retained gastric contents during single endoscopic procedures but not with combined upper endoscopy and colonoscopy.

Hospitals around the country are conserving critical intravenous fluid supplies to cope with a shortage that may last months.

More evidence emerges that robotic animals can help older adults with depression and isolation.

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

Antiviral treatment is underutilized among children and adolescents hospitalized with influenza, according to research published in the Nov. 14 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Using data from two U.S. influenza surveillance networks, Aaron M. Frutos, Ph.D., from the CDC

Stereotactic radiosurgery (SRS) is safe and effective for management of Koos grade I vestibular schwannomas (VS) compared with observation, according to a study published online Nov. 6 in Neurosurgery.Othman Bin-Alamer, M.B.B.S., from the University of Pittsburgh Medical Center, and colleagues evaluated the safety and efficacy of SRS v

Escalating heat exposure poses a major threat to maternal and neonatal health, according to a review published online Nov. 5 in Nature Medicine.Darshnika P. Lakhoo, M.B.Ch.B., M.P.H., from University of the Witwatersrand in Johannesburg, South Africa, and colleagues conducted a systematic literature review to assess heat impacts o

Genetic risk for Alzheimer's disease and dementia appeared to be partly offset by high levels of cardiorespiratory fitness, U.K. Biobank data suggested. Overall, high cardiorespiratory fitness was associated with better global...

Treatment with metformin was associated with a reduction in asthma attacks among patients with asthma and type 2 diabetes, with additional reductions observed with the use of GLP-1 receptor agonists, according to a self-controlled...

Adding an anthracycline to adjuvant chemotherapy for TOP2A-normal early breast cancer significantly improved disease-free survival (DFS) but not overall survival (OS) at 10 years, and doubled the risk of heart failure, a randomized...

In the wake of the presidential election, physicians have been flocking to the social media platform Bluesky, asserting there's now a critical mass of medical professionals engaging on the site. Many told MedPage Today that...

For the first time since 2021, a pill used to help people quit smoking—varenicline—will again be available from the NHS.

From enforcing the Comstock Act to reversing guidance on emergency care, there are multiple avenues for the Trump administration to dramatically limit access to abortion, even without a federal ban, legal experts told MedPage...

After a certain threshold, cumulative opioid use was associated with higher dementia risk, a study of adults over age 60 in Denmark showed. In a nested case-control study, opioid use above 90 total standardized doses (TSDs...

President-elect Donald Trump says he is nominating Mehmet Oz, MD, a heart surgeon who hosted a long-running television talk show, to lead the Centers for Medicare & Medicaid Services (CMS). "Dr. Oz will be a leader in incentivizing...

Lipoprotein(a), or Lp(a), was successfully reduced in phase II trials of muvalaplin and zerlasiran. (JAMA) The possibility of a drug interaction between SGLT2 inhibitors and statins was not supported by rates of rhabdomyolysis...

Among adults with outpatient respiratory syncytial virus (RSV) infections across six RSV seasons, roughly one in 20 were hospitalized within 28 days, according to a large cohort study that used data from three health record databases...

Long-term use of many common cardiovascular drugs was tied to fewer dementia diagnoses but anti-platelet use of any duration was associated with higher dementia risk, Swedish data showed. (Alzheimer's & Dementia) Repeated...

High cardiorespiratory fitness is associated with better cognitive performance and lower risk of dementia in the long term, including in people with a genetic predisposition to dementia, show the findings of a study published online in the British Journal of Sports Medicine.

You don't need to know the role of the artery of Adamkiewicz or mechanisms of liver failure. You can Google it. And, you don't need to remember it once you've looked it up -- Google will remember for you! The internet, with...

President-elect Donald J. Trump has said that he would nominate Dr. Mehmet Oz to serve as administrator of the Centers for Medicare and Medicaid Services (CMS).

Adoption of a new version of the Model for End-Stage Liver Disease, known as MELD 3.0, closed the gap in access to liver transplant between men and women, an analysis showed. Since MELD 3.0 was implemented in July 2023, a higher...

High-dose supplements of docosahexaenoic acid (DHA), an omega-3 fatty acid, showed no effect on hippocampal volume or cognition, according to findings from the placebo-controlled PreventE4 trial presented at the Clinical Trials...

In the United States, there are currently more adults living with cerebral palsy than children. Despite this, the Centers for Disease Control and Prevention still label cerebral palsy as "the most common motor disability in childhood."

Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene Therapy. To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, they added cyclosporin (CsH) to increase transduction by inhibiting lentiviral restriction factors.

A study that investigates low-dose ketamine (LDK) as an adjunct to morphine for treating acute pain has been published in the Academic Emergency Medicine journal.

Binge drinking in early adults can lead to long-lasting and potentially permanent dysregulation in the brain, according to a new study in mice, led by researchers at Penn State. They found that neurons, cells that transmit information in the brain via electrical and chemical signals, showed changes following binge drinking were similar in many ways to those seen with cognitive decline.

At the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) annual meeting, Michael Hehir, MD, of the University of Vermont in Burlington, participated in a debate on integrating novel and traditional...

Experts convened by the National Institutes of Health (NIH) have identified five elements of a brain-based condition that has emerged as a leading cause of vision impairment starting in childhood in the United States and other industrialized nations.

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

CHICAGO -- A bumetanide nasal spray in development for heart failure was well-tolerated and showed reliable rates of absorption compared with oral and intravenous delivery in a phase I trial of healthy volunteers. The 68-person...

Alzheimer's disease affects more than 50 million people worldwide, often devastating both the individuals who have it and their families and loved ones. It has no known cure, and the slow, progressive nature of the disease makes early diagnosis difficult.

A new study led by researchers at The University of Texas at Austin and Harvard Medical School reveals surprising findings about how babies exposed to gestational diabetes mellitus (GDM) grow during their first year of life.

Psychotic-like experiences resemble symptoms of psychosis, but are milder, less frequent and much more common than psychotic disorders. While these symptoms do not constitute a disorder diagnosed as psychosis, they can still be disruptive, distressing or detrimental to functional capacity. Typical psychotic-like experiences include perceptual distortions and hallucinations, suspicious paranoid thi

In a recent study, Tel Aviv Sourasky Medical Center has shed light on physician attitudes toward novel anti-amyloid treatments (ATT) for Alzheimer's disease (AD), revealing a spectrum of opinions across key specialties. With Israel's health system structured to provide universal health care, the high out-of-pocket costs for new AD therapies have raised questions among medical professionals about t

A type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results of a clinical trial published in JAMA Oncology.

Life is a series of small events: making morning coffee, letting the dog out, opening a laptop, letting the dog back in. Add them all up and you have a full day. Our brains are committed to observing and processing the events that make up our daily lives, said Jeff Zacks, the Edgar James Swift Professor in Arts & Sciences and chair of the Department of Psychological & Brain Sciences. "Knowing wher

The U.S. Preventive Services Task Force (USPSTF) recommends early screening for syphilis infection in all pregnant women (grade A recommendation). This recommendation forms the basis of a draft recommendation statement published online Nov. 19.Researchers for the Agency for Healthcare Research and Quality in Rockville, Maryland, reviewed new ev

Cognitive neuroscientists at Trinity College Dublin have published new research describing a brand new approach to making habit change achievable and lasting.

For patients with chronic kidney disease (CKD), the risk for emergently treated hypocalcemia with denosumab increases with worsening CKD stage, according to a study published online Nov. 19 in the Annals of Internal Medicine.Steven T. Bird, Ph.D., Pharm.D., from the U.S. Food and Drug Administration in Silver Spring, Maryland, and coll

Sleep environment characteristics and social drivers of poor health and family vulnerability differ for sleep-related sudden unexplained infant death (SUID) in infants prenatally substance-exposed versus nonexposed infants, according to a study published online Nov. 19 in Pediatrics.Stephanie Anne Deutsch, M.D., from Nemours Children's

For patients with immunoglobulin G (IgG)4-related disease, inebilizumab reduces the risk for flares and increases the likelihood of flare-free complete remission, according to a study published online Nov. 14 in the New England Journal of Medicine to coincide with the annual meeting of the American College of Rheumatology, held from Nov. 14 t

Deep learning with pose artificial intelligence (AI) may offer a scalable, minimally invasive method for neuro-telemetry in the neonatal intensive care unit (NICU), according to a study published online Nov. 11 in eClinicalMedicine.Alec Gleason, from the Albert Einstein College of Medicine in New York City, and colleagues assessed whet

Colchicine fails to improve knee pain, function, or size of synovial effusions with painful knee osteoarthritis (OA), according to a study presented at the annual meeting of the American College of Rheumatology, held from Nov. 14 to 19 in Washington, D.C.Jonathan Samuels, M.D., from NYU Langone in Rye Brook, New York, and colleagues assessed wh

Candida parapsilosis is a yeast fungus that can colonize the skin and digestive tract of humans and is usually harmless. However, it can cause severe wound and tissue infections, including life-threatening septicemia, in people who are immunocompromised as a result of cancer or organ transplants or with serious medical conditions requiring prolonged hospitalization.

Many young patients with early-onset cancer report having a fertility preservation (FP) discussion with their health care professional prior to treatment, according to a research letter published online Nov. 12 in JAMA Network Open.Samantha R. Keller, from Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues eva

Middle-aged adults with long-term fluctuations in blood pressure may face a higher risk for sudden cardiac death than their peers with more consistent blood pressure readings, a large new study suggests.

It's generally estimated that around 10% of pregnant people struggle to meet their nutritional needs—but the real number could be far higher, according to new research from Stevens Institute of Technology.

In research published in Child Psychiatry and Human Development, a research team led by the University of Minnesota Medical School has found that Creativity Camp, a two-week arts intervention delivered as a day camp, had a positive impact on mental health and well-being in adolescents with depression.

Three-fourths of U.S. adults are now overweight or have obesity, with nearly 260 million predicted to have overweight or obesity by 2050. (The Lancet) According to another study in The Lancet, almost 60% of the over 800 million...

Internet use may be associated with higher levels of life satisfaction, better self-reported health, and fewer symptoms of depression among adults aged over 50 in 23 countries, suggests a study published in Nature Human Behaviour. The findings have potential implications for public health policies and practices, particularly in countries with aging populations and limited mental health services.

The increasing incidence of pancreatic cancer in young Americans is mainly due to increased detection of smaller, early-stage endocrine cancer, according to a research letter published online Nov. 19 in the Annals of Internal Medicine.Vishal R. Patel, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and colleagues examined wh

Approximately 16% of the global population, or about 890 million people, suffer from obesity. The World Health Organization (WHO) has recognized obesity as a significant health issue and highlighted its impact on the quality of life and overall health of individuals across the world.

Babies who are prenatally exposed to illicit drugs or alcohol are known to be at higher risk for sudden unexpected infant death (SUID). A new study by a Nemours Children's Health researcher, published in Pediatrics, shows that caregivers of prenatally exposed infants were twice as likely to be impaired at the time of death.