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All articles tagged: Hematology & Oncology

HealthDay 20 November at 04.01 PM

Teledermoscopy Accurate for Detecting Skin Cancers

Teledermoscopy has high accuracy for detecting skin cancers, according to a research letter published online Nov. 9 in the Journal of the American Academy of Dermatology.Jenne P. Ingrassia, from New York Medical College in Valhalla, and colleagues conducted a prospective diagnostic accuracy study to compare the accuracy of telemedici

HealthDay 20 November at 11.06 AM

Four Million Americans Could Lose Health Coverage Once ACA Credits Expire

If Congress lets health care tax credits established during the pandemic expire, 4 million Americans will become uninsured, a new analysis warns.The tax credits, which have significantly lowered out-of-pocket costs for millions of Americans, are set to expire at the end of 2025."Allowing these credits to expire will force families to c

HealthDay 20 November at 11.04 AM

Surgeon General Says U.S. Smoking Rates Have Tumbled, But Not for Everyone

Although the United States has made significant headway in curbing cigarette smoking and secondhand smoke exposure, a new report finds deep divisions remain and they run along predictable fault lines.Disparities in tobacco use continue to persist by income and occupation, geography, education, race and ethnicity, sexual orientation and gender

HealthDay 19 November at 11.50 PM

President-Elect Trump to Pick Mehmet Oz to Head CMS

President-elect Donald Trump says he will nominate Mehmet Oz, M.D., to head the Centers for Medicare & Medicaid Services.In a statement, Trump said that Oz will "work closely with Robert Kennedy Jr. to take on the illness industrial complex, and all the horrible chronic diseases left in its wake," The New York Times reported. Trump

HealthDay 19 November at 04.19 PM

Half of Young Cancer Patients Report Fertility Preservation Discussion With Provider

Many young patients with early-onset cancer report having a fertility preservation (FP) discussion with their health care professional prior to treatment, according to a research letter published online Nov. 12 in JAMA Network Open.Samantha R. Keller, from Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues eva

HealthDay 19 November at 03.59 PM

Study Looks at Increasing Incidence of Pancreatic Cancer in Younger Adults

The increasing incidence of pancreatic cancer in young Americans is mainly due to increased detection of smaller, early-stage endocrine cancer, according to a research letter published online Nov. 19 in the Annals of Internal Medicine.Vishal R. Patel, M.D., M.P.H., from Brigham and Women's Hospital in Boston, and colleagues examined wh

HealthDay 19 November at 03.53 PM

Barriers to Widespread Access to Cancer Medications Include Excessive Cost

Barriers to widespread access to cancer treatments include excessive cost and lack of affordability, according to a review published online Nov. 18 in Cancer.Arafat H. Tfayli, M.D., from the American University of Beirut Medical Center, and colleagues conducted a systematic review to examine the current state of cancer drug development

HealthDay 18 November at 04.28 PM

ChemoRT Then Immunochemotherapy Then Surgery Promising in Unresectable Esophageal Cancer

For patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC), chemoradiotherapy (CRT) followed by immunochemotherapy (iCT) and then surgery is promising, according to a study published online Nov. 15 in Clinical Cancer Research.Xin Wang, from the Chinese Academy of Medical Sciences and Peking Union Medical C

HealthDay 18 November at 04.17 PM

Bleeding Risk Increased With NSAID Use for VTE Patients Receiving Anticoagulants

Patients with venous thromboembolism (VTE) initiating oral anticoagulants have an increased risk for bleeding when using nonsteroidal anti-inflammatory drugs (NSAIDs), according to a study published online Nov. 17 in the European Heart Journal.Søren Riis Petersen, from Aarhus University Hospital in Denmark, and colleagues conducted a na

HealthDay 15 November at 04.39 PM

Anxiety, Depression Increased in Pancreatic Cancer Patients With Palliative Care Consult

Newly diagnosed pancreatic cancer patients receiving palliative care (PC) consultations have an increased prevalence of anxiety and depression, according to a study recently published in Healthcare.Divya S. Subramaniam, Ph.D., M.P.H., from the Saint Louis University School of Medicine, and colleagues conducted a retrospective analysis o

HealthDay 15 November at 04.36 PM

Low Frequency of Discipline Seen for Physician-Spread Misinformation

The frequency of medical board discipline for physician-spread misinformation is low, according to a study published online Nov. 12 in JAMA Network Open.Richard S. Saver, J.D., from the University of North Carolina School of Law in Chapel Hill, compared the level of professional discipline of physicians for spreading medical misinformat

HealthDay 14 November at 11.47 PM

President-Elect Trump Nominates Robert F. Kennedy Jr. to Lead HHS

President-elect Donald Trump has chosen Robert F. Kennedy Jr. to head the U.S. Department of Health and Human Services.The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid, and Medicare.In a stat

HealthDay 14 November at 04.55 PM

ASH: Complications Common With Controlled Ovarian Hyperstimulation in Sickle Cell Anemia

Many individuals with sickle cell anemia undergoing controlled ovarian hyperstimulation (COH) with oocyte cryopreservation (OC) have complications, according to a study scheduled for presentation at the annual meeting of the American Society of Hematology, to be held from Dec. 9 to 12 in San Diego.Marti Goldenberg, D.O., from Johns Hopkins Hos

HealthDay 14 November at 04.49 PM

Neoantigen DNA Vaccines Safe, Induce Response in Triple-Negative Breast Cancer

Neoantigen DNA vaccines are safe and capable of inducing neoantigen-specific immune responses in patients with triple-negative breast cancer, according to a study published online Nov. 14 in Genome Medicine.Xiuli Zhang, M.D., from the Washington University School of Medicine in St. Louis, and colleagues developed a neoantigen DNA vacc

HealthDay 14 November at 04.40 PM

ASH: GLP-1 RA Use Tied to Lower Rate of Venous Thromboembolism in Diabetes

For patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a lower risk for venous thromboembolism (VTE), according to a study scheduled for presentation at the annual meeting of the American Society of Hematology, to be held from Dec. 9 to 12 in San Diego.Cho Han Chiang, M.D.,

HealthDay 13 November at 04.49 PM

Late-Stage Lymphoma Less Likely for Young With Continuous Medicaid Coverage

Children and adolescents and young adults (AYAs) diagnosed with lymphoma and insured by Medicaid who maintain Medicaid coverage before diagnosis are less likely to have late-stage disease, according to a study published online Nov. 12 in Blood Advances.Xinyue Zhang, from the Emory University Rollins School of Public Health in Atlanta

HealthDay 13 November at 04.02 PM

Overtreatment of Prostate Cancer Increasing in Men With Short Life Expectancy

In the active surveillance era, overtreatment of men with limited life expectancy (LE) decreased for those with low-risk prostate cancer, but increased for those with intermediate-risk and high-risk disease from 2000 to 2019, according to a study published online Nov. 11 in JAMA Internal Medicine.Timothy J. Daskivich, M.D., from

HealthDay 12 November at 03.54 PM

Few High-Risk Individuals Have Heard of, Discuss Lung Cancer Screening

Few high-risk individuals have heard of or have discussed lung cancer screening (LCS) with a health care practitioner, according to a research letter published online Oct. 30 in JAMA Network Open.Kalyani Sonawane, Ph.D., from the Medical University of South Carolina in Charleston, and colleagues examined LCS communication for U.S. indi

HealthDay 08 November at 04.54 PM

Long-Term Complications After Prostate Cancer Treatment Not Uncommon

Prostate cancer (PCA) treatment is associated with increased rates of complications in the 12 years after treatment, according to a study published online Nov. 7 in JAMA Oncology.Joseph M. Unger, Ph.D., from the Fred Hutchinson Cancer Center in Seattle, and colleagues characterized long-term treatment-related adverse effects and complica

HealthDay 07 November at 11.07 PM

Travel Time to Tanning Facilities Negatively Linked to Melanoma Incidence

There is a negative association between travel time to tanning facilities and county-level melanoma incidence rates, according to a study published online Nov. 7 in the Journal of Investigative Dermatology.Guixing Wei, Ph.D., from Brown University in Providence, Rhode Island, and colleagues examined the association between melanoma inc

HealthDay 07 November at 04.25 PM

Cancer Disparities Evident Across Human Development Index, Projected to Widen

Cancer disparities are evident across the Human Development Index (HDI) and are projected to increase by 2050, according to a study published online Nov. 5 in JAMA Network Open.Habtamu Mellie Bizuayehu, Ph.D., M.P.H., from The University of Queensland in Australia, and colleagues measured the global burden of 36 cancers in 2022 by sex,

HealthDay 07 November at 04.16 PM

Cutaneous Malignant Melanoma Incidence Increasing Among the Elderly

From 1987 to 2016, there was a considerable increase in the incidence of cutaneous malignant melanoma (CMM) among the elderly in the United States, according to a study published online Oct. 28 in Cancer Screening and Prevention.Ruofei Du, Ph.D., from Shaanxi University of Chinese Medicine in Xianyang, and colleagues examined CMM incid

HealthDay 07 November at 04.14 PM

Omega-6 and Omega-3 Fatty Acid Levels Inversely Tied to Cancer Incidence

There is a small inverse association between plasma omega-6 and omega-3 polyunsaturated fatty acids (PUFAs) and cancer, according to a study published online Oct. 17 in the International Journal of Cancer.Yuchen Zhang, from the University of Georgia in Athens, and colleagues investigated the associations of plasma omega-3 and omeg

HealthDay 06 November at 05.04 PM

Risk Factors Found for Neurogenic Bladder After Rectal Cancer Surgery

Lower abdominal visceral fat area (VFA), older age, and prolonged surgery are independent risk factors for developing postoperative neurogenic bladder (PONB) after rectal cancer surgery, according to a study published online Sept. 27 in BMC Gastroenterology.Tomohiro Matsui, M.D., from Kyoto Prefectural University of Medicine in Japan,

HealthDay 06 November at 04.47 PM

AI Aids Risk Prediction Classification for Prostate Cancer

Artificial intelligence (AI)-based risk classification improves prognostication with localized prostate cancer, according to a study published online Oct. 24 in JCO Precision Oncology.Jonathan David Tward, M.D., Ph.D., from the University of Utah in Salt Lake City, and colleagues developed a clinically usable risk grouping system usin

HealthDay 05 November at 09.48 PM

Most Adults Lack Knowledge About Pancreatic Cancer

Most people continue to believe that pancreatic cancer affects only the elderly and that there is nothing they can do to reduce their risk, according to the results of a new survey from The Ohio State University.A national web- and telephone-based survey (Oct. 4 to 7) of 1,004 respondents was conducted by The Ohio State University Comprehensive

HealthDay 05 November at 04.34 PM

Smoking Cessation Aids Survival Even Following a Cancer Diagnosis

Evidence-based smoking cessation treatment within six months of a cancer diagnosis maximizes survival benefit, according to a study published online Oct. 31 in JAMA Oncology.Paul M. Cinciripini, Ph.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues examined the association between time of entry in

HealthDay 05 November at 04.21 PM

Open Primary Retroperitoneal Lymph Node Dissection Shows Acceptable Morbidity

Open primary retroperitoneal lymph node dissection (RPLND) has an acceptable morbidity profile in men with testicular cancer, according to a study published online Sept. 3 in BJU International.Jacob D. McFadden, M.D., from the Indiana University School of Medicine in Indianapolis, and colleagues characterized current perioperative

HealthDay 04 November at 11.44 PM

Policies About Late-Career Physicians Are Considered Successful

Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study published online Nov. 5 in the Annals of Internal Medicine.Noting that some health care organizations (HCOs) have adopted LCP policies requiring cognitive, physical, and practice

HealthDay 04 November at 05.01 PM

More Than One-Third Have ED Visit Within 90 Days Before Cancer Diagnosis

More than one-third of patients have emergency department use within 90 days before a confirmed cancer diagnosis, according to a study published online Nov. 4 in CMAJ, the journal of the Canadian Medical Association.Keerat Grewal, M.D., from Sinai Health at the University of Toronto, and colleagues conducted a retrospective, population-b

HealthDay 04 November at 05.00 PM

Certain Pesticides Tied to Increased Prostate Cancer Incidence, Mortality

Some pesticides are associated with increased prostate cancer incidence and mortality, according to a study published online Nov. 4 in Cancer.Simon John Christoph Soerensen, M.D., from the Stanford University School of Medicine in California, and colleagues examined the potential role of agricultural pesticide exposure in prostate cancer

HealthDay 04 November at 04.40 PM

New Set of Risk Factors Can Boost Detection of Suspicious Skin Lesions

A new set of skin cancer risk factors can improve detection of suspicious skin lesions, according to a study published online Sept. 6 in Scientific Reports.Shafiqul Islam, Ph.D., from the University of Essex in Colchester, England, and colleagues examined artificial intelligence (AI) models that use patient metadata consisting of 23 attr

HealthDay 01 November at 03.51 PM

Uninsurance Plays Major Role in Racial Disparities Seen in Cancer Diagnosis

Lack of health insurance coverage accounts for a considerable proportion of racial and ethnic disparities in advanced-stage diagnoses of cancer, according to a study published online Oct. 30 in the Journal of the National Cancer Institute.Parichoy Pal Choudhury, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined

HealthDay 01 November at 03.41 PM

ACG: GLP-1 RAs Tied to Lower Risk for Early-Onset Colorectal Cancer

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can decrease the risk for developing early-onset colorectal cancer (EO-CRC) in patients with diabetes regardless of weight, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Temitope Olasehinde, M.D., from

HealthDay 31 October at 03.35 PM

Inavolisib + Palbociclib-Fulvestrant Improves Survival in Advanced Breast Cancer

Inavolisib plus palbociclib-fulvestrant yields significantly longer progression-free survival than placebo plus palbociclib-fulvestrant in patients with PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer, according to a study published in the Oct. 3

HealthDay 31 October at 03.25 PM

ACG: 2000 to 2022 Saw Rise in Early-Onset CRC Mortality in the United States

Early-onset colorectal cancer (EO-CRC) mortality rose in the United States over the past two decades, most notably in patients aged 20 to 44 years, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 25 to 30 in Philadelphia.Yazan Abboud, M.D., from Rutgers New Jersey Medical School

HealthDay 30 October at 03.37 PM

Multigene Signature Can Help Tailor Chemo for Operable Triple-Negative Breast Cancer

For patients with operative triple-negative breast cancer, a multigene signature can help tailor adjuvant chemotherapy, according to a study published online Oct. 23 in The BMJ.Min He, from Fudan University Shanghai Cancer and Key Laboratory of Breast Cancer, and colleagues conducted a randomized phase 3 trial in seven cancer centers

HealthDay 30 October at 03.22 PM

Cell-Free Blood DNA Tests Less Effective Than Other CRC Screening

Cell-free DNA blood tests (cf-bDNA) may be more costly and less effective for colorectal cancer (CRC) screening than other screening modalities, according to a study published online Oct. 29 in the Annals of Internal Medicine.Uri Ladabaum, M.D., from the Stanford University School of Medicine in California, and colleagues estimated t

HealthDay 29 October at 10.50 PM

Many Seniors at Risk for Financial Precarity From Cost of Hospital Stay

Many Medicare beneficiaries are at risk for financial hardship from the costs of a single hospital stay, according to a study published online Oct. 29 in the Annals of Internal Medicine.Paula Chatterjee, M.D., M.P.H., from the University of Pennsylvania Perelman School of Medicine, and colleagues identified beneficiaries who would face

HealthDay 29 October at 03.53 PM

Restaging MRI Can Predict Survival With Rectal Cancer

Restaging magnetic resonance imaging (MRI) can predict organ preservation and survival with rectal cancer, according to a study published online Sept. 3 in Radiology.Hannah Williams, M.D., from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues evaluated the ability of restaging MRI to predict oncolog

HealthDay 29 October at 03.33 PM

Guideline-Concordant Care Less Likely With Non-Hispanic Black Race

For older patients with breast cancer, non-Hispanic Black race is associated with increased odds of not receiving guideline-concordant care (GCC) and less timely initiation of treatment, according to a study published online Oct. 24 in JAMA Network Open.Brenda S. Castillo, M.D., from the University of Pennsylvania in Philadelphia, and

HealthDay 28 October at 03.52 PM

ACS: Many Cancer Patients Face Lasting Financial Difficulties

Many patients with cancer diagnoses experience lasting financial difficulties, according to two studies presented at the annual meeting of the American College of Surgeons, held from Oct. 19 to 22 in San Francisco.Jorge L. Gomez-Mayorga, M.D., from Beth Deaconess Medical Center in Boston, and colleagues conducted a difference-in-differences anal

HealthDay 25 October at 03.49 PM

Medicaid Expansion Increases Guideline-Concordant Treatment for Breast Cancer

Expanding Medicaid is associated with an increase in receipt of guideline-concordant treatment among nonelderly women newly diagnosed with hormone receptor (HR)-negative, human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to a study published online Oct. 23 in the Journal of the National Comprehensive Cancer Network</

HealthDay 24 October at 03.26 PM

Protracted Radiation Exposure Linked to Hematologic Cancer Mortality

Protracted low-dose exposure to ionizing radiation among radiation-monitored workers is associated with mortality due to some hematologic malignancies, according to a study published online in the October issue of The Lancet Hematology.Klervi Leuraud, Ph.D., from the Institut de Radioprotection et de Sûreté Nucléaire in Fontenay-aux-R

HealthDay 24 October at 02.32 PM

Higher Heathy Eating Index Score Beneficial in Prostate Cancer

Higher adherence to American dietary guideline recommendations may be associated with a lower risk for grade reclassification in men diagnosed with grade group 1 (GG1) prostate cancer, according to a study published online Oct. 17 in JAMA Oncology.Zhou Tony Su, M.D., from the Johns Hopkins University School of Medicine in Baltimore, a

HealthDay 23 October at 03.09 PM

FDA Appoints New Head of Medical Devices

The U.S. Food and Drug Administration announced Tuesday that it has appointed Dr. Michelle Tarver to head its division that oversees medical devices.The appointment of a new director for the <a href="https://www.fda.gov/about-fda/fda-organization/center-devices-and-r

HealthDay 23 October at 02.40 PM

FDA Approves Vyloy for Advanced Gastric or Gastroesophageal Junction Cancer

The U.S. Food and Drug Administration has approved Vyloy (zolbetuximab-clzb) in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma who

HealthDay 22 October at 10.48 PM

AAO: Corneal Toxicity Reported With Mirvetuximab Soravtansine

For patients receiving mirvetuximab soravtansine (MIRV) treatment for primary gynecologic malignancies, corneal toxicity is not uncommon, but usually resolves, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held from Oct. 18 to 21 in Chicago.Filippos Vingopoulos, M.D., Ph.D., from Stanford Univers

HealthDay 22 October at 03.33 PM

FIT Completion, Yield Rates Similar in Those Aged 45 to 49 Versus 50 Years

Fecal immunochemical test (FIT) completion and yield rates are similar in people aged 45 to 49 years and those aged 50 years, according to a study published online Oct. 22 in the Annals of Internal Medicine.Theodore R. Levin, M.D., from Kaiser Permanente Northern California in Oakland, and colleagues examined FIT completion and yield i

HealthDay 22 October at 03.33 PM

No Objective Improvement Seen in Cognitive Function With Exercise During Chemo

Aerobic exercise does not result in differences in objective cognitive function after chemotherapy completion among women with breast cancer, according to a study published online Oct. 21 in Cancer.Jennifer Brunet, Ph.D., from the University of Ottawa in Ontario, Canada, and colleagues examined the effects of an aerobic exercise interv

HealthDay 22 October at 03.23 PM

Computer-Aided Detection Colonoscopies Tied to Improved Adenoma Detection Rate

Compared with conventional colonoscopy, computer-aided detection (CADe) system-enhanced colonoscopies have an increased rate of adenomas per colonoscopy and higher adenoma detection rates, according to a review published online Oct. 22 in the Annals of Internal Medicine.Saeed Soleymanjahi, M.D., M.P.H., from Mass General Brigham and th

HealthDay 22 October at 03.14 PM

Cancer Detection Recovered Following Pandemic Disruptions

Overall, cancer detection in the United States recovered meaningfully in 2021 following substantial disruptions in 2020, according to a study published online Oct. 14 in&nbsp;JAMA Network Open.Uriel Kim, M.D., Ph.D., from the Cedars-Sinai Medical Center in Los Angeles, and colleagues evaluated the disruption and potential recovery in c

HealthDay 21 October at 10.56 PM

Measures of Social Support Linked to Cancer Screening

Measures of social support are associated with screening for specific types of cancer, according to a study published online Oct. 18 in Cancer Causes &amp; Control.Jordan Baeker Bispo, Ph.D., M.P.H., from the American Cancer Society in Atlanta, and colleagues examined the impact of living arrangements and residential stability on cancer

HealthDay 21 October at 03.50 PM

IDSA: Antibiotics for Seven Days Feasible for Patients Hospitalized With Bloodstream Infections

Treating hospitalized patients with bloodstream infections with antibiotics for seven days is noninferior to treating for 14 days, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 16 to 19 in &nbsp;Los Angeles.Nick Daneman, M.D., and Rob Fowler, M.D., from the University

HealthDay 21 October at 03.47 PM

Novel Imaging Technique Accurate for Detecting Clear-Cell Renal Cell Cancer

⁸⁹Zr-labeled monoclonal antibody ([⁸⁹Zr]Zr-girentuximab) for positron emission tomography-computed tomography (PET-CT) is accurate for detecting patients with clear-cell renal cell carcinoma, according to a study published online in the October issue of The Lancet Oncology.Brian Shuch, M.D., from the University of California Los Angeles

HealthDay 21 October at 03.35 PM

Pembrolizumab Aids Survival With High-Risk Endometrial Cancer

Pembrolizumab plus chemotherapy improves disease-free survival (DFS) in patients with high-risk endometrial cancer after surgery with curative intent, according to a study published online Oct. 16 in the&nbsp;Journal of Clinical Oncology.Brian M. Slomovitz, M.D., from Mount Sinai Medical Center in Miami Beach, and colleagues conducted a

HealthDay 21 October at 03.26 PM

Sensitivity Reduced on Low-Dose Pediatric CT Scans for Small Lung Nodules

Two lung-nodule computer-aided detection (CAD) systems demonstrated reduced sensitivity on low- versus standard-dose computed tomography (CT) scans for small nodules in pediatric patients, according to a study published online Oct. 9 in the American Journal of Roentgenology.Russell C. Hardie, Ph.D., from the University of Dayton in Ohio

HealthDay 18 October at 04.10 PM

Breast Cancer Risk Elevated With Levonorgestrel-Releasing Intrauterine System Use

Women using levonorgestrel-releasing intrauterine systems (LNG-IUS) have an increased risk for breast cancer, according to a study published online Oct. 16 in the Journal of the American Medical Association.Lina Steinrud Mørch, Ph.D., from the Danish Cancer Institute in Copenhagen, Denmark, and colleagues examined breast cancer risk wit

HealthDay 17 October at 04.04 PM

Excess Adiposity Plays Role in Postmenopausal HR-Positive Breast Cancer

Excess body fat plays a role in postmenopausal hormone receptor-positive breast cancer, which could be underestimated using only body mass index (BMI), according to a study published online Oct. 17 in the Journal of Epidemiology and Community Health.Naiara Cubelos-Fernández, from the University of León Institute of Biomedicine in Spai

HealthDay 17 October at 04.04 PM

Stereotactic Body Radiotherapy Viable Alternative for Localized Prostate Cancer

Stereotactic body radiotherapy (SBRT) is noninferior to conventional or moderately fractionated radiotherapy for localized prostate cancer (PC), according to a study published online Oct. 16 in the&nbsp;New England Journal of Medicine.Nicholas van As, from the Royal Marsden Hospital in London, and colleagues assessed whether SBRT is n

HealthDay 17 October at 03.59 PM

Tenecteplase Has Similar Safety to TPA for Acute Ischemic Stroke

For patients with acute ischemic stroke (AIS), tenecteplase (TNK) has improved functional outcome and reduced disability and similar safety to alteplase (tissue plasminogen activator [TPA]), according to a study published online Oct. 16 in Neurology.Lina Palaiodimou, M.D., Ph.D., from the National and Kapodistrian University of Athens

HealthDay 16 October at 09.55 PM

Progression-Free Survival Improved With Nivolumab + AVD in Hodgkin Lymphoma

For patients with stage III or IV Hodgkin lymphoma, nivolumab with doxorubicin, vinblastine, and dacarbazine (N+AVD) yields longer progression-free survival (PFS) than brentuximab vedotin with doxorubicin, vinblastine, and dacarbazine (BV+AVD), according to a study published online Oct. 16 in the New England Journal of Medicine.Alex

HealthDay 16 October at 03.06 PM

FDA Approves Itovebi for Locally Advanced, Metastatic Breast Cancer

The U.S. Food and Drug Administration approved Itovebi (inavolisib), in combination with palbociclib (Ibrance) and fulvestrant, for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer.Th

HealthDay 16 October at 02.55 PM

IOTA ADNEX at 10 Percent Has Higher Sensitivity for Ovarian Cancer

The International Ovarian Tumour Analysis consortium (IOTA) Assessment of Different Neoplasias in the Adnexa (ADNEX) at 10 percent is more sensitive, but less specific, for diagnosing ovarian cancer compared with Risk of Malignancy 1 (RMI1) at 250, according to a study published in the October issue of The Lancet Oncology.Sudha Sunda

HealthDay 16 October at 02.33 PM

Radon Exposure Tied to Higher Risk for Childhood Leukemia

Exposure to radon levels, even below current recommended levels, heightens the risk for childhood leukemia, according to a study published in the December 2024 issue of&nbsp;Science of the Total Environment.Matthew Bozigar, from Oregon State University in Corvallis, and colleagues investigated the association between domestic radon e

HealthDay 15 October at 09.43 PM

2008 to 2022 Saw Rise in Industry-Sponsored Adult Cancer Clinical Trials

In the United States, there is a growing reliance on industry to conduct cancer clinical research, according to a study published online Sept. 27 in the&nbsp;Journal of Clinical Oncology.Joseph M. Unger, Ph.D., from the Fred Hutchinson Cancer Center in Seattle, and colleagues evaluated cancer trial enrollment patterns from 2008 to 2022

HealthDay 15 October at 04.01 PM

FDA Approves Hympavzi for Hemophilia

The U.S. Food and Drug Administration (FDA) approved Hympavzi (marstacimab-hncq) for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients aged 12 years and older with hemophilia A without factor VIII inhibitors or hemophilia B without factor IX inhibitors.Unlike other drugs that replace a c

HealthDay 15 October at 03.54 PM

Guidelines Developed for EBUS-TBNA Specimen Processing, Handling

In a new clinical guideline issued by the American College of Chest Physicians and published online Sept. 27 in CHEST, recommendations are presented for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen processing and handling.Noting that EBUS-TBNA has become the standard for initial lung cancer diag

HealthDay 11 October at 09.07 PM

Letter Nudges Increase Likelihood of Flu Vaccination for Adults With Chronic Diseases

For patients aged 18 to 64 years with chronic diseases, electronically delivered letter nudges increase influenza vaccination rates compared with usual care, according to a study published online Oct. 11 in the Journal of the American Medical Association.Niklas Dyrby Johansen, M.D., Ph.D., from Copenhagen University Hospital -- Herlev a

HealthDay 11 October at 09.07 PM

Medical Financial Hardships Shared in Cancer-Linked Crowdfunding Stories

A considerable proportion of cancer-related crowdfunding stories share experiences of medical financial hardships and health-related social needs (HRSNs), according to a research letter published online Oct. 10 in JAMA Oncology.Zhiyuan Zheng, Ph.D., from the American Cancer Society in Atlanta, and colleagues used a large natural languag

HealthDay 11 October at 03.57 PM

Liberal Transfusion Strategy May Avert Unfavorable Neurological Outcome

For patients with acute brain injury, a liberal transfusion strategy is associated with a lower risk for having an unfavorable neurological outcome, according to a study published online Oct. 9 in the Journal of the American Medical Association to coincide with the annual congress of the European Society of Intensive Care Medicine, held from O

HealthDay 11 October at 03.53 PM

Industry Payments Common for Physician Peer Reviewers of Top Journals

More than half of U.S. physician peer reviewers for the most influential medical journals receive industry payments, according to a research letter published online Oct. 10 in the&nbsp;Journal of the American Medical Association.David-Dan Nguyen, M.P.H., from the University of Toronto, and colleagues characterized payments by drug and m

HealthDay 11 October at 03.42 PM

Extracorporeal Blood Purification Can Cut Cardiac Surgery-Associated AKI

For patients undergoing nonemergent cardiopulmonary bypass (CPB), use of an extracorporeal blood purification (EBP) device is associated with a lower rate of cardiac surgery-associated acute kidney injury (CSA-AKI), according to a study published online Oct. 9 in the Journal of the American Medical Association to coincide with the annual congr

HealthDay 11 October at 03.19 PM

Anatomic Changes Can Be Seen With MRI-Linac for Glioblastoma Patients

For patients with glioblastoma imaged daily with magnetic resonance imaging (MRI)-linear accelerator (linac) throughout the chemoradiation therapy course, anatomic changes can be detected, according to a study published online Sept. 30 in the International Journal of Radiology Oncology - Biology - Physics.Kaylie Cullison, Ph.D., from th

HealthDay 10 October at 10.11 PM

Hematologic Cancer Develops in Some Patients Receiving Eli-Cel

Hematologic cancer develops in some patients receiving lentiviral elivaldogene autotemcel (eli-cel) gene therapy for cerebral adrenoleukodystrophy, according to a study published in the Oct. 10 issue of the New England Journal of Medicine.Christine N. Duncan, M.D., from Harvard Medical School in Boston, and colleagues analyzed periphe

HealthDay 10 October at 03.55 PM

Aerobic Physical Activity Reduces Depression in Patients With Cancer

Aerobic physical activity (APA) is associated with a small but significant reduction in depression among adults with cancer, according to a review published online Oct. 8 in JAMA Network Open.Matthew Kulchycki, M.D., from the University of Manitoba in Winnipeg, Canada, and colleagues conducted a systematic review and meta-analysis to

HealthDay 10 October at 03.45 PM

Time to Testosterone Recovery Varies With ADT Duration

For men receiving androgen deprivation therapy (ADT) for prostate cancer, time to testosterone recovery (TR) varies with ADT duration, according to a study published online Sept. 19 in European Urology.Wee Loon Ong, M.B.B.S., from Monash University in Melbourne, Australia, and colleagues obtained individual patient data from randomize

HealthDay 10 October at 03.31 PM

Increasing Amount of Breast Cancer-Specific Death Due to Stage 1, 2 Disease

Patients with stage I/II breast cancers have excellent prognosis, but account for more than 60 percent of breast cancer-specific death (BCSD) because of their large absolute volumes, according to a study published online Sept. 30 in the&nbsp;Journal of the National Cancer Institute.&nbsp;Michal Marczyk, Ph.D., from Silesian University

HealthDay 10 October at 03.27 PM

Availability, Timeliness of Availability of New Cancer Drugs Vary

Across countries, there are considerable disparities in the availability and timeliness of availability of new cancer drugs, according to a study published online Oct. 8 in BMJ Global Health.Meng Li, Ph.D., from Tufts Medical Center in Boston, and colleagues examined the availability and timeliness of availability of new cancer drugs

HealthDay 09 October at 10.18 PM

Risk for Second Melanoma Up for Those With First Melanoma Diagnosis

Patients with a first melanoma diagnosis have an increased risk for a second melanoma diagnosis, regardless of race and ethnicity, according to a research letter published online Oct. 9 in JAMA Dermatology.Shoshana Zhang, from Dell Medical School at the University of Texas at Austin, and colleagues examined the absolute risk of second

HealthDay 09 October at 10.15 PM

Cancer Incidence Increased for People With Multiple Sclerosis

Cancer incidence is increased overall in people with multiple sclerosis (PwMS), with considerable differences depending on cancer type, age, and sex, according to a study published online Oct. 9 in Neurology.Chloe Pierret, from Rennes University in France, and colleagues conducted a 10-year nationwide retrospective matched cohort stud

HealthDay 09 October at 04.06 PM

Metabolic-Bariatric Surgery Tied to Reduced Risk for Pancreatic Cancer in Those With Obesity

For individuals with obesity, metabolic-bariatric surgery (MBS) is associated with a reduced risk for pancreatic cancer, especially among those with type 2 diabetes (T2D), according to a review published online Oct. 9 in Diabetes/Metabolism Research and Reviews.Angeliki M. Angelidi, M.D., Ph.D., from the Broad Institute of MIT and Har

HealthDay 09 October at 03.53 PM

Online Tool Enhances Decision-Making for Timing of Breast Reconstruction

An online decision aid is helpful for breast cancer patients deciding about immediate breast reconstruction (BR) after mastectomy, according to a study published in the October issue of&nbsp;Plastic and Reconstructive Surgery.Jacqueline A. ter Stege, from the Netherlands Cancer Institute in Amsterdam, and colleagues evaluated the effi

HealthDay 08 October at 10.52 PM

Socioeconomic Factors Tied to Sickle Cell Complications in Preschoolers

For preschool-aged children with sickle cell disease (SCD), social determinants of health (SDOH) are associated with the risk for complications and hospitalizations, according to a study published online Oct. 7 in Blood Advances.Hamda Khan, from St. Jude Children's Research Hospital in Memphis, Tennessee, and colleagues examined whether

HealthDay 08 October at 10.48 PM

American Society for Radiation Oncology, Sept. 29-Oct. 2

The annual meeting of the American Society for Radiation Oncology was held from Sept. 29 to Oct. 2 in Washington, D.C., drawing more than 8,500 participants from around the world, including physicians, oncology nurses, radiation therapists, biologists, physicists, and other cancer researchers. The confer

HealthDay 08 October at 04.12 PM

Social Risk Factors Tied to Lower Odds of Receiving Preventive Services

Social risk factors are associated with decreased odds of receiving preventive services such as mammograms, Papanicolaou (Pap) tests, flu or pneumococcal vaccines, and colonoscopies, according to a study published online Oct. 4 in&nbsp;JAMA Network Open.Tamara Schroeder, M.D., from the University of California, Davis, and colleagues exa

HealthDay 08 October at 04.08 PM

AI May Identify Women at Risk for Future Breast Cancer

Artificial intelligence (AI) scores may be able to estimate the risk for future breast cancer and lead to earlier diagnosis, according to a study published online Oct. 3 in&nbsp;JAMA Network Open.Jonas Gjesvik, from the Norwegian Institute of Public Health in Oslo, and colleagues examined whether a commercial artificial intelligence (AI

HealthDay 08 October at 04.05 PM

Cilta-Cel Treatment Safe, Effective for Relapsed/Refractory Multiple Myeloma

Ciltacabtagene autoleucel (cilta-cel) CAR T-cell therapy for relapsed/refractory multiple myeloma (RRMM) results in a deep and durable response, according to a study published online Oct. 4 in&nbsp;Blood.Surbhi Sidana, M.D., from Stanford University in California, and colleagues reported outcomes with cilta-cel in the standard-of-care s

HealthDay 08 October at 11.45 AM

EPA Finalizes Rule to Require Removal of Lead Pipes in U.S. Water System

The U.S. Environmental Protection Agency on Tuesday finalized a rule that will require the removal of all lead pipes from the country's water systems.“We’ve known for decades that lead exposure has serious long-term impacts for children’s health. And yet, millions of lead service lines are still delivering drinking water to homes,”&nbsp;EPA Admi

HealthDay 07 October at 04.10 PM

Cancer Survival Rates Rose for Young Adults After Affordable Care Act

During the first decade of the Affordable Care Act (ACA), survival and mortality increased among young adults with cancer who were eligible for dependent care expansion (DCE), according to a study published online Oct. 7 in&nbsp;Cancer.Michael Roth, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues c

HealthDay 07 October at 04.08 PM

One-Dose HPV Vaccination Averts Similar Number of Cancers as Two Doses

A one-dose human papillomavirus (HPV) vaccination program is projected to prevent a similar number of cervical cancers as a two-dose program, according to a study published online Oct. 7 in CMAJ, the journal of the Canadian Medical Association.Mélanie Drolet, Ph.D., from the Université Laval in Québec City, and colleagues used an individ

HealthDay 07 October at 03.53 PM

Liso-Cel Has Favorable Safety Profile for Outpatients With Large B-Cell Lymphoma

For patients with relapsed/refractory large B-cell lymphoma (LBCL), the autologous, CD19-directed, 4-1BB chimeric antigen receptor T-cell product, lisocabtagene maraleucel (liso-cel), is safe for outpatients and inpatients and is efficacious, according to a study published online Sept. 30 in Blood Advances.Yuliya Linhares, M.D., from the

HealthDay 07 October at 03.50 PM

Overall Survival Improving for Umbilical Cord Blood Transplant

For umbilical cord blood transplant (UCBT), overall survival has improved over time, according to a study published in the October issue of Transplantation and Cellular Therapy.Karen Ballen, M.D., from the University of Virginia Health System in Charlottesville, and colleagues compared outcomes of UCBT by social determinants of health in

HealthDay 07 October at 03.41 PM

Tobacco-Free Generation Could Prevent 40 Percent of Predicted Lung Cancer Deaths Globally

Implementation of a tobacco-free generation could substantially reduce global lung cancer mortality, according to a study published in the October issue of&nbsp;The Lancet Public Health.Julia Rey Brandariz, Ph.D., from the Universidade de Santiago de Compostela in Spain, and colleagues estimated the impact of eliminating tobacco smoking

HealthDay 04 October at 09.22 PM

2021 USPSTF Recommendation Boosted Colorectal Cancer Screening

Uptake of colorectal cancer (CRC) screening increased after the 2021 U.S. Preventive Services Task Force (USPSTF) recommendation that all average-risk individuals aged 45 to 49 years should receive screening, according to a study published online Oct. 3 in&nbsp;JAMA Network Open.Sunny Siddique, M.P.H., from the Yale School of Public Heal

HealthDay 04 October at 09.17 PM

Fear of Cancer Recurrence Common Decades After Surviving Childhood Cancer

A third of childhood cancer survivors experience fear of recurrence even decades later, according to a study published online Oct. 3 in&nbsp;JAMA Network Open.Alex Pizzo, from Concordia University in Montreal, and colleagues characterized the prevalence of and risk factors for clinically significant fear of cancer recurrence in adult sur

HealthDay 04 October at 03.37 PM

ASTRO: Many Patients Have Cognitive Recovery After Brain Radiotherapy

Many patients with brain metastases who experience initial neurocognitive failure (NCF) following brain radiation therapy demonstrate recovery, with greater rates of cognitive recovery (CR) for stereotactic radiosurgery (SRS), according to a study presented at the annual meeting of the American Society for Radiation Oncology, held from Sept. 29 to Oct.

HealthDay 04 October at 03.34 PM

ASTRO: Intensity-Modulated RT, Proton Beam Therapy Have Similar Outcomes in Prostate Cancer

Intensity-modulated radiation therapy (IMRT) and proton beam therapy (PBT) offer similar outcomes for patients with localized prostate cancer, according to a study presented at the annual meeting of the American Society for Radiation Oncology, held from Sept. 29 to Oct. 2 in Washington, D.C.Jason A. Efstathiou, M.D., from Massachusetts General Ho

HealthDay 04 October at 03.30 PM

Accelerating Smoking Elimination Could Prevent Millions of Deaths by 2050

A substantial smoking-attributable burden can be avoided by accelerating the pace of smoking elimination, according to a study published in the October issue of The Lancet Public Health.Stein Emil Vollset, M.D., M.P.H., from the Norwegian Institute of Public Health in Bergen, and fellow GBD 2021 Tobacco Forecasting Collaborators used the

HealthDay 04 October at 03.20 PM

cfDNA Fragmentome, Protein Analyses Detect Ovarian Cancer

Integrated cell-free DNA (cfDNA) fragmentome and protein analyses detect ovarian cancers with high performance, according to a study published online Sept. 30 in Cancer Discovery.Jamie E. Medina, Ph.D., from the Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins University School of Medicine in Baltimore, and colleagues used

HealthDay 03 October at 03.38 PM

Extended Lymphadenectomy Fails to Improve Survival in Bladder Cancer

For patients with muscle-invasive bladder cancer, extended lymphadenectomy does not improve disease-free or overall survival compared with standard lymphadenectomy, according to a study published in the Oct. 3 issue of the New England Journal of Medicine.Seth P. Lerner, M.D., from the Baylor College of Medicine in Houston, and colleagu

HealthDay 03 October at 03.23 PM

Progress Toward Cutting Racial Mortality Disparities Stalling, Reversing

U.S. racial disparities in mortality decreased from 1999 to 2015 for Black men and to 2011 for Black women, followed by stagnation or regression, according to a study published online Sept. 30 in&nbsp;JAMA Network Open.Adith S. Arun, from the Yale School of Medicine in New Haven, Connecticut, and colleagues sought to compare excess age

HealthDay 02 October at 09.56 PM

Female Residents Underrepresented in High-Compensation Specialties

Female physicians remain underrepresented among residents entering high-compensation specialties, according to a research letter published online Sept. 30 in the&nbsp;Journal of the American Medical Association.Karina Pereira-Lima, Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined national trends in the prop

HealthDay 02 October at 03.13 PM

ASTRO: Hypofractionated Radiation Therapy Safe After Breast Reconstruction

For patients undergoing breast reconstruction, a 16-fraction course of hypofractionated postmastectomy radiation therapy (PMRT) is noninferior to a 25-fraction conventional course, according to a study presented at the annual meeting of the American Society for Radiation Oncology (ASTRO), held from Sept. 29 to Oct. 2 in Washington, D.C.Matthew

HealthDay 02 October at 03.11 PM

Olanzapine, Prochlorperazine Both Alleviate Refractory Chemo-Related Nausea

Olanzapine may be better than prochlorperazine for reducing refractory nausea in patients with breast cancer starting a high/moderate emetogenic chemotherapy regimen, according to a study presented at the American Society of Clinical Oncology annual Quality Care Symposium, held from Sept. 27 to 28 in San Francisco.&nbsp;Luke Joseph Peppone, Ph

HealthDay 02 October at 03.04 PM

Anti-CTAg Antibodies Identified in Stage I, II Melanoma

Circulating antibodies against cancer-testis antigens (CTAgs) are found in stage I and stage II melanoma plasma samples, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. 25 to 28 in Amsterdam.Cristina Vico-Alonso, M.D., from Monash University Public Health and Preventi

HealthDay 02 October at 03.02 PM

Certain Oral Bacteria Tied to Risk for New Head, Neck Squamous Cell Cancer

Certain oral bacteria are a risk factor for development of head and neck squamous cell cancer (HNSCC), according to a study published online Sept. 26 in&nbsp;JAMA Oncology.Soyoung Kwak, Ph.D., from the New York University Grossman School of Medicine in New York City, and colleagues tested whether oral bacterial and fungal microbiomes

HealthDay 02 October at 02.51 PM

First-Trimester Iron Screening Can ID Women at Risk for Later Deficiency

Screening pregnant women during their first trimester with a target ferritin concentration of &gt;60 μg/L may identify those at risk for iron deficiency later in pregnancy, according to a study published online Sept. 26 in the&nbsp;American Journal of Clinical Nutrition.Elaine K. McCarthy, Ph.D., from University College Cork in Irelan

HealthDay 01 October at 10.45 PM

2023 Cisplatin Shortage Tied to Use of Alternatives for Head, Neck Cancer

The 2023 cisplatin shortage led to a shift in utilization to alternative therapies for head and neck cancer (HNC), resulting in significant cost increases, according to a study presented at the American Society of Clinical Oncology annual Quality Care Symposium, held from Sept. 27 to 28 in San Francisco.Puneeth Indurlal, M.D., from the U.S. Onco

HealthDay 01 October at 03.55 PM

Upward Trends in Breast Cancer Incidence Continuing Among Women

Upward trends in breast cancer incidence among women have continued, according to a study published online Oct. 1 in CA: A Cancer Journal for Clinicians.Angela N. Giaquinto, M.S.P.H., from the American Cancer Society in Atlanta, and colleagues presented the biennial update of statistics on breast cancer among women using incidence and m

HealthDay 01 October at 03.52 PM

Study Looks at Efficacy of Hemoglobin Thresholds for Transfusion

For patients with acute myocardial infarction (MI) and anemia, 30-day risks for death or recurrent MI seem to increase with lower hemoglobin thresholds for transfusion, according to a study published online Oct. 1 in the Annals of Internal Medicine.Gerard T. Portela, Ph.D., from the University of Pittsburgh, and colleagues estimated the

HealthDay 30 September at 04.12 PM

No Infections Seen After Transperineal Biopsy for Prostate Cancer

For patients with suspicion for prostate cancer, transperineal biopsy has similar cancer detection rates as transrectal biopsy but a significantly lower risk for infection, according to a research letter published online Sept. 19 in JAMA Oncology.Jim C. Hu, M.D., M.P.H., from the New York Presbyterian Weill Cornell Medicine Hospital in

HealthDay 30 September at 03.44 PM

Cancer Incidence Rates in 2021 Indicate Return to Prepandemic Levels

The overall incidence rates for all cancer sites and specific cancer sites returned to prepandemic levels in 2021, according to a study published online Sept. 24 in the Journal of the National Cancer Institute.Nadia Howlader, Ph.D., from the National Cancer Institute in Rockville, Maryland, and colleagues used 2021 incidence data from

HealthDay 27 September at 04.13 PM

Omitting Biopsy With Negative MRI Reduces Detection of Clinically Insignificant Prostate Cancer

Omitting biopsy in patients with negative magnetic resonance imaging (MRI) results is associated with a significantly reduced relative risk for detecting clinically insignificant prostate cancer, according to a study published in the Sept. 26 issue of the New England Journal of Medicine.Jonas Hugosson, M.D., Ph.D., from Sahlgrenska Aca

HealthDay 27 September at 03.54 PM

Cognitive Behavioral Therapy Program Aids Insomnia in Breast Cancer Survivors

An in-home, voice-activated cognitive behavioral therapy (CBT) program improves insomnia symptoms among breast cancer survivors, according to a study published online Sept. 24 in&nbsp;JAMA Network Open.Claire M. Starling, M.P.H., from the MedStar Health Research Institute in Washington, D.C., and colleagues assessed the efficacy of a C

HealthDay 26 September at 03.50 PM

Non-Hispanic Black Patients Have Disparities in HCT Use for Hematologic Cancers

Non-Hispanic Black patients in the United States appear to have persistent disparities in terms of hematopoietic cell transplantation (HCT) for various hematologic cancers, according to a study published online Sept. 18 in JAMA Network Open.Theresa Hahn, Ph.D., from Roswell Park Comprehensive Cancer Center in Buffalo, New York, and c

HealthDay 26 September at 03.44 PM

Melanoma Risk Increased After Radioactive Iodine Treatment for Primary Thyroid Cancer

Patients with primary thyroid cancer who receive radioactive iodine therapy have an elevated risk for melanoma and other nonkeratinocyte skin cancers when limiting the cancer site to the head and neck, according to a study published online Sept. 19 in JAMA Network Open.Shawheen J. Rezaei, from the Stanford University School of Medici

HealthDay 26 September at 03.41 PM

Fidanacogene Elaparvovec Superior to Prophylaxis for Hemophilia B

For patients with hemophilia B, fidanacogene elaparvovec, an adeno-associated virus (AAV) gene-therapy vector for hemophilia B containing a high-activity human factor IX variant, is superior to prophylaxis, according to a study published in the Sept. 26 issue of the New England Journal of Medicine.Adam Cuker, M.D., from the Universit

HealthDay 25 September at 03.42 PM

Early Adoption of DOAC Dashboard Reduces Off-Label Prescribing

Early adoption of the direct oral anticoagulant (DOAC) population management dashboard, the purpose of which includes pharmacist review and correction of off-label dosing prescriptions, is associated with reduced rates of off-label DOAC dosing prescription and reduced bleeding, according to a study published online Sept. 9 in the Journal of the

HealthDay 25 September at 03.37 PM

Risk for Stroke, TIA Increased in Adults With Sickle Cell Disease

Adults with sickle cell disease (SCD) have an increased risk for stroke and transient ischemic attack (TIA), according to a study published online Sept. 20 in Blood.Olubusola Oluwole, M.D., from the University of Pittsburgh, and colleagues determined the cumulative incidence and rates for primary and recurrent strokes and TIAs in pe

HealthDay 25 September at 03.33 PM

Wearable Tied to Better Physical Activity Recovery Following Lung Cancer Surgery

A postoperative wearable device may improve physical activity and patient-reported dyspnea at six months after lung cancer surgery, according to a study published online Sept. 20 in&nbsp;JAMA Network Open.Junghee Lee, M.D., from the Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues evaluated the effect

HealthDay 25 September at 03.28 PM

Childhood Trauma Tied to Worse Health, Risks Later in Life

Childhood adversity is associated with worse biological health and an elevated risk for many major health problems, according to a study published in the January 2025 issue of&nbsp;Brain, Behavior, and Immunity.Jenna Alley, Ph.D., from the University of California, Los Angeles, and colleagues conducted latent class analyses (LCAs) t

HealthDay 24 September at 11.02 PM

Prevalence of Obesity 40.3 Percent in U.S. From August 2021 to August 2023

The prevalence of obesity among adults was 40.3 percent during August 2021 to August 2023, according to a September data brief published by the National Center for Health Statistics.Samuel D. Emmerich, D.V.M., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from the National Health and Nutritio

HealthDay 24 September at 10.58 PM

14 Percent of U.S. Adults Meet Criteria for Absolute Iron Deficiency

A considerable proportion of U.S. adults has absolute and functional iron deficiency, according to a study published online Sept. 24 in JAMA Network Open.Yahya M.K. Tawfik, Pharm.D., from Brigham and Women's Hospital in Boston, and colleagues conducted a cross-sectional study analyzing data from the National Health and Nutritional Exa

HealthDay 24 September at 03.46 PM

Measurable Residual Disease Results After Consolidation Therapy Predictive of Relapse in Pediatric Leukemia

For children with acute lymphoblastic leukemia (ALL), measurable residual disease (MRD) after the end of first consolidation (EOC) can be used to predict the need for subsequent MRD measurements, according to a study published online Sept. 10 in Leukemia.Janine Stutterheim, M.D., Ph.D., from the Princess Máxima Center for Pediatric On

HealthDay 24 September at 03.05 PM

Financial Hardship Common in Patients With Cancer

Nearly half of patients with cancer experience some level of financial hardship (FH), according to a study published online Aug. 15 in&nbsp;JCO Oncology Practice.Betina Yanez, Ph.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues used data from 2,305 participants in the Northwestern University

HealthDay 23 September at 04.01 PM

Incidence of Cardiovascular Disease Higher for Seniors With Cancer

The incidence of a composite cardiovascular disease (CVD) end point is increased among older adults with cancer, especially those with metastatic, hematological, and lung cancer, according to a study published online Sept. 23 in Cancer.Jaidyn Muhandiramge, M.D., from Monash University in Melbourne, Australia, and colleagues conducted a

HealthDay 23 September at 03.53 PM

Pomalidomide Efficacious in Hereditary Hemorrhagic Telangiectasia

For patients with hereditary hemorrhagic telangiectasia (HHT), pomalidomide yields a significant reduction in epistaxis severity, according to a study published in the Sept. 19 issue of the New England Journal of Medicine.Hanny Al-Samkari, M.D., from Massachusetts General Hospital in Boston, and colleagues conducted a randomized, place

HealthDay 23 September at 03.50 PM

High Response Incidence Seen for Axatilimab in Recurrent, Refractory GVHD

For patients with recurrent or refractory graft-versus-host disease (GVHD), the colony-stimulating factor 1 receptor (CSF1R)-blocking antibody axatilimab results in a high incidence of overall response, according to a study published in the Sept. 19 issue of the New England Journal of Medicine.Daniel Wolff, M.D., from University Hospit

HealthDay 20 September at 03.44 PM

Higher Incarceration Rates Linked to Increased Cancer Mortality Rates

Higher incarceration rates are associated with increased county- and state-level cancer mortality rates, according to a study published online Sept. 17 in the Journal of the National Cancer Institute.Jingxuan Zhao, Ph.D., M.P.H., from the American Cancer Society in Atlanta, and colleagues examined the association of county-level jail a

HealthDay 20 September at 03.42 PM

Tivozanib Has Efficacy in Advanced Renal Cell Carcinoma Post-ICI Therapy

For patients with metastatic renal cell carcinoma (mRCC) and progression during or after one to two prior lines of therapy, including one immune checkpoint inhibitor (ICI), tivozanib has efficacy, according to a study published online Sept. 13 in The Lancet to coincide with the annual meeting of the European Society for Medical Oncology, held

HealthDay 20 September at 03.29 PM

Adjuvant Pembrolizumab Improves Survival in Muscle-Invasive Urothelial Cancer

Disease-free survival is significantly longer with adjuvant pembrolizumab than observation among patients with high-risk muscle-invasive urothelial carcinoma after radical surgery, according to a study published online Sept. 18 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncol

HealthDay 20 September at 12.06 PM

FDA Says Drug Makers Will Stop Producing Fentanyl 'Lollipops'

Controversial fentanyl lollipops and similar products will no longer be made by drug makers, the U.S. Food and Drug Administration has announced.Known as TIRF medications, these products contain fentanyl and are used to manage breakthrough pain in cancer patients who have become tolerant to around-the-clock opioid therapy, the FDA said in a <a

HealthDay 19 September at 10.10 PM

Pembrolizumab + Chemo Beneficial for Early-Stage Triple-Negative Breast Cancer

For patients with early-stage triple-negative breast cancer, neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab yields a significant improvement in overall survival compared with neoadjuvant chemotherapy alone, according to a study published online Sept. 15 in the New England Journal of Medicine to coincide with

HealthDay 19 September at 03.54 PM

DBT Increases Cancer Detection Versus Digital Mammography

Digital breast tomosynthesis (DBT) can increase cancer detection compared with two-dimensional digital mammography (DM), according to a study published online Sept. 17 in Radiology.Liane Elizabeth Philpotts, M.D., from the Yale School of Medicine in New Haven, Connecticut, and colleagues compared cancer types and stages over three ye

HealthDay 19 September at 03.42 PM

Excess Body Weight Linked to Increased Risk for Second Primary Neoplasm

Among cancer survivors, excess body weight is associated with an increased risk for a second primary malignant neoplasm, according to a study published online Sept. 17 in JAMA Network Open.Clara Bodelon, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined whether excess body weight is associated with the risk

HealthDay 19 September at 03.35 PM

Adjuvant Durvalumab Extends Survival in Small Cell Lung Cancer

For patients with limited-stage small cell lung cancer, adjuvant therapy with durvalumab leads to significantly longer overall and progression-free survival, according to a study published online Sept. 13 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from Sept.

HealthDay 19 September at 03.31 PM

Long-Term Survival Benefit Seen for Nivolumab in Advanced Melanoma

For patients with advanced melanoma, there is a survival benefit for nivolumab plus ipilimumab and for nivolumab monotherapy compared with ipilimumab monotherapy, according to a study published online Sept. 15 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from S

HealthDay 18 September at 03.34 PM

Neoadjuvant Chemo Boosts Structure Preservation Rates in Nasal, Sinus Cancer

Neoadjuvant platinum-based chemotherapy improves structure preservation (SP) for patients with T3, T4a, and selected T4b resectable nasal and paranasal sinus squamous cell carcinoma (NPNSCC) requiring orbital or skull base resection, according to a study presented at the annual meeting of the European Society for Medical Oncology, held from Sept. 1

HealthDay 18 September at 11.05 AM

FDA Expands Use of Breast Cancer Drug Kisqali

Women with early-stage breast cancer may now take Kisqali, a medication already approved for advanced disease, following the U.S. Food and Drug Administration's expanded approval of the treatment, drug maker Novartis announced Tuesday.“The FDA approval of Kisqali for this early breast cancer p

HealthDay 17 September at 09.23 PM

Model Can Predict, Stratify Liver Cancer Risk in Noncirrhotic Chronic Hep B

A new prognostic model can predict and stratify hepatocellular carcinoma (HCC) risk in noncirrhotic adult patients with chronic hepatitis B (CHB), according to a study published online Sept. 17 in the Annals of Internal Medicine.Gi-Ae Kim, M.D., Ph.D., from Kyung Hee University Hospital in Seoul, South Korea, and colleagues developed

HealthDay 17 September at 09.13 PM

Aromatase Inhibitors Not Linked to CAC in Postoperative Breast Cancer Patients

For postoperative patients with breast cancer, the duration of aromatase inhibitor (AI) treatment is not associated with the risk for coronary artery calcium (CAC), according to a study published online Sept. 17 in the Canadian Journal of Cardiology.Yu Hiasa, M.D., from the Ehime University Graduate School of Medicine in Toon, Japan,

HealthDay 17 September at 03.21 PM

Early, Virtual Palliative Care Feasible for Advanced Lung Cancer

The delivery of early, virtual palliative care has similar effects on quality of life as in-person care in patients with advanced non-small cell lung cancer (NSCLC), according to a study published online Sept. 11 in the&nbsp;Journal of the American Medical Association.Joseph A. Greer, Ph.D., from Massachusetts General Hospital in Bost

HealthDay 17 September at 03.15 PM

Lactated Ringer Solution Better Than Normal Saline for Sickle Cell Pain Crises

Administration of lactated Ringer (LR) solution has a small but significant improvement on sickle cell disease outcomes versus normal saline (NS) for fluid resuscitation during pain crises, according to a study published online Sept. 9 in&nbsp;JAMA Internal Medicine.Augusta K. Alwang, M.D., from Boston University, and colleagues compa

HealthDay 17 September at 02.52 PM

Study Looks at Sex Differences in Melanoma Incidence

Melanoma rates differ for men and women, including in terms of ages of occurrence and locations of melanoma, according to a study published online June 17 in the Journal of Investigative Dermatology.Catherine M. Olsen, Ph.D., from the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and colleagues analyzed long-term m

HealthDay 16 September at 04.03 PM

AI Can Use ECG Images to Define Risk for Cancer Therapy-Linked Cardiac Dysfunction

For patients undergoing treatment for certain types of cancer, artificial intelligence (AI) can use electrocardiographic (ECG) images to define the risk for cardiac dysfunction, according to a study published online Sept. 2 in Circulation: Cardiovascular Quality and Outcomes.Evangelos K. Oikonomou, M.D., D.Phil., from Yale School of Me

HealthDay 16 September at 03.51 PM

Moderate Hypofractionation Shows Good Safety Outcomes in Breast Cancer

For patients with breast cancer, moderate hypofractionation (MHF) shows an improved safety profile, cosmesis, and quality of life compared with conventional fractionation (CF), with equivalent oncologic outcomes, according to a study published online Sept. 11 in The BMJ.Shing Fung Lee, M.B.B.S., from the National University Hospital in

HealthDay 13 September at 02.44 PM

Tusamitamab Ravtansine Does Not Extend Survival With Nonsquamous NSCLC

Tusamitamab ravtansine (tusa rav), an immunoconjugate, does not improve progression-free survival (PFS) in patients with previously treated advanced nonsquamous non-small cell lung cancer (NSCLC), according to a study presented at the International Association for the Study of Lung Cancer 2024 World Conference on Lung Cancer, held from Sept. 7 to 10 i

HealthDay 12 September at 09.31 PM

Long-Course Chemoradiotherapy Preferred TNT Regimen for Rectal Cancer

For patients with locally advanced rectal cancer pursuing organ preservation, long-course chemoradiotherapy (LCCRT) is the preferred total neoadjuvant therapy (TNT) regimen, according to a study published online Sept. 11 in the Annals of Oncology to coincide with the European Society for Medical Oncology Congress 2024, being held from Sept.

HealthDay 12 September at 09.27 PM

Risk for Venous Thromboembolism Up for Those With Sickle Cell Trait

Individuals with sickle cell trait (SCT) have an increased risk for venous thromboembolism (VTE), according to a study published online Sept. 12 in Blood Advances.Keng-Han Lin, Ph.D., from 23andMe in Sunnyvale, California, and colleagues leveraged data from the 23andMe Research cohort (4,184,082 participants) to calculate the ancestr

HealthDay 12 September at 03.59 PM

Perioperative Nivolumab Beneficial for Resectable NSCLC

For patients with resectable non-small-cell lung cancer (NSCLC), perioperative nivolumab is associated with event-free survival (EFS) benefit compared with neoadjuvant nivolumab, according to a study presented at the International Association for the Study of Lung Cancer 2024 World Conference on Lung Cancer, held from Sept. 7 to 10 in San Diego.

HealthDay 12 September at 03.38 PM

Risk for Second Primary Cancer May Be No Higher With CAR T-Cell Versus Standard of Care

The overall second primary malignancy (SPM) point estimate was 5.8 percent for patients receiving chimeric antigen receptor (CAR) T-cell therapy, according to a study published online Sept. 11 in Clinical Cancer Research.Tobias Tix, from LMU Klinikum in Munich, and colleagues conducted a systematic review to delineate the frequency a

HealthDay 11 September at 03.51 PM

Alternative Explanation Conditions Often Delay Lung Cancer Diagnosis

Conditions offering alternative explanations for lung cancer symptoms are associated with increased diagnostic intervals, according to a study published online Aug. 23 in the&nbsp;British Journal of Cancer.Imogen Rogers, from Brighton and Sussex Medical School in the United Kingdom, and colleagues examined the diagnostic interval fr

HealthDay 10 September at 10.19 PM

Omitting 5-FU Bolus Does Not Reduce Survival in Advanced Cancer

Omission of 5-fluorouracil (5-FU) from the first-line FOLFOX, FOLFIRI, and FOLFIRINOX regimens is not associated with reduced survival among patients with advanced colorectal, gastroesophageal, and pancreatic cancers, according to a study published online Sept. 5 in the Journal of the National Comprehensive Cancer Network.Chengwei Pen

HealthDay 10 September at 04.15 PM

Melanoma Incidence, Mortality Declining in Those Aged 30 to 49 Years

For adults aged 30 to 49 years, there has been a decline in melanoma incidence and mortality, according to a study published online Sept. 8 in JAMA Dermatology to coincide with the annual meeting of the European Society for Medical Oncology, held from Sept. 13 to 17 in Barcelona, Spain.Hildur Helgadottir, M.D., Ph.D., from the Karolin

HealthDay 10 September at 03.18 PM

Palliative Low-Dose Radiotherapy Improves Pain in Hepatic Cancer

For adults with hepatocellular carcinoma or liver metastases, low-dose liver radiotherapy plus best supportive care improve pain compared with best supportive care alone, according to a study published online Sept. 5 in The Lancet Oncology.Laura A. Dawson, M.D., from the Princess Margaret Cancer Centre at the University of Toronto, an

HealthDay 09 September at 09.00 PM

Most Patients With Stage I PDAC Are Upstaged on Histopathology

More than 70 percent of patients with stage I pancreatic ductal adenocarcinoma (PDAC) and close to 30 percent with stage II PDAC are upstaged on histopathology, according to a research letter published online Sept. 5 in the Journal of the American Medical Association.Gerardo Perrotta, M.D., from Cedars-Sinai Medical Center in Los Angele

HealthDay 09 September at 04.02 PM

Psychological Illness, CVD Risk Increased for Relatives, Spouses of Cancer Patients

Cancer diagnosis is associated with an increased risk for psychological illness and cardiovascular disease among first-degree relatives and spouses of patients, according to a study published online Sept. 9 in Cancer.Using data from the Utah Population Database, Mouneeb M. Choudry, M.D., from the Mayo Clinic in Phoenix, and colleagues c

HealthDay 09 September at 03.28 PM

Women With Liver Cancer Less Likely Than Men to Receive Liver Transplant

Women with&nbsp;hepatocellular carcinoma (HCC) are less likely to receive a&nbsp;deceased-donor liver transplant (DDLT)&nbsp;and more likely to die while wait-listed than men, according to a study published online Sept. 4 in&nbsp;JAMA Surgery.David C. Cron, M.D., from Massachusetts General Hospital in Boston, and colleagues examined whe

HealthDay 06 September at 09.37 PM

Socioeconomic Disparities Impact Immunotherapy Use in Urologic Cancers

Immunotherapy (IO) utilization is increasing over time, but significant socioeconomic disparities exist for patients with advanced clear cell renal cell carcinoma (ccRCC) and urothelial carcinoma of the bladder (UC), according to a study published in the November issue of Urologic Oncology: Seminars and Original Investigations.Levi Holl

HealthDay 06 September at 04.01 PM

U.S. Cancer Incidence Trends Lower Than Expected in 2021

U.S. cancer incidence trends improved in 2021, but continued to be lower than expected, according to a study published online Sept. 6 in JAMA Network Open.Todd Burus, from the University of Kentucky in Lexington, and colleagues conducted a cross-sectional, population-based study of cancer incidence trends using the Surveillance, Epidemi

HealthDay 06 September at 03.41 PM

Lung Complications + Rheumatoid Arthritis Increase Risk for Lung Cancer

The risk for lung cancer is high in patients with rheumatoid arthritis (RA) and pulmonary complications, according to a study published online Sept. 3 in&nbsp;Modern Rheumatology.Shunsuke Mori, M.D., Ph.D., from the Kumamoto Saishun Medical Center in Koshi, Japan, and colleagues assessed the incidence and predictive factors of lung canc

HealthDay 05 September at 10.41 PM

Lower Uptake of HPV Vaccine Seen for Girls With Mental Illness

Girls with mental illness and neurodevelopmental conditions have lower uptake of human papillomavirus (HPV) vaccination, according to a study published in the September issue of The Lancet Public Health.Kejia Hu, Ph.D., from the Karolinska Institutet in Stockholm, and colleagues conducted a population-based cohort study to examine the

HealthDay 05 September at 10.38 PM

Doxorubicin + Trabectedin Tied to Increased Survival in Metastatic Leiomyosarcoma

For patients with metastatic or surgically unresectable leiomyosarcoma, combination therapy with doxorubicin and trabectedin is associated with improved overall and progression-free survival compared with doxorubicin alone, according to a study published online Sept. 4 in the New England Journal of Medicine.Patricia Pautier, M.D., fro

HealthDay 05 September at 06.56 PM

U.S. Youth Vaping Drops to Lowest Level in a Decade

Just 5.9% of American middle and high school students now vape, a big drop from the 7.7% who did so a year ago, new government data shows.Put another way, about 1.6 million youth now say they used e-cigarettes at least once over the past month, compared to 2.1 million in 2023.Among those who say they vape, 23.6% said they do it on a dai

HealthDay 05 September at 02.53 PM

World Trade Center Exposure Linked to Increased DNA Methylation

World Trade Center (WTC) exposure is associated with increased DNA methylation, which may contribute to breast cancer, according to a study published in the June issue of Environmental Epidemiology.Stephanie Tuminello, Ph.D., M.P.H., from the NYU Grossman School of Medicine in New York City, and colleagues examined the DNA methylation

HealthDay 05 September at 02.49 PM

Lung Function Stable Three Years After Hematopoietic Cell Transplant in Sickle Cell

Lung function remains stable over three years after hematopoietic cell transplant (HCT) among patients with sickle cell disease (SCD), according to a study published online June 26 in the Annals of the American Thoracic Society.A. Parker Ruhl, M.D., from the National Institutes of Health in Bethesda, Maryland, and colleagues examined

HealthDay 04 September at 11.12 PM

Suicide Risk Higher for Cancer Patients Not Proceeding With Recommended Surgery

Higher suicide deaths are seen among cancer patients who do not undergo recommended surgery, according to a research letter published online Sept. 3 in&nbsp;JAMA Network Open.Michael L. Chen, from Stanford University in California, and colleagues used the Surveillance, Epidemiology, and End Results Program 17 Registries database (200

HealthDay 04 September at 04.24 PM

Ruling Out Other Conditions Needed With Suspected Interstitial Cystitis

Efforts to rule out bladder tumors and tuberculosis are still essential in the follow-up of patients with suspected interstitial cystitis (IC), according to a study published online Aug. 11 in the International Journal of Gynecology &amp; Obstetrics.Hyun Ju Jeong, from the Seoul National University College of Medicine in South Korea,

HealthDay 04 September at 03.10 PM

Likelihood of Return for Screening Low After False-Positive Mammogram

Women are less likely to return for subsequent screening after false-positive mammography results, according to a study published online Sept. 3 in the Annals of Internal Medicine.Diana L. Miglioretti, Ph.D., from the University of California in Davis, and colleagues examined the association between screening mammography results and

HealthDay 03 September at 04.09 PM

Interleukin-6 May Boost Prediction of Obesity-Related Cancers

In patients with newly diagnosed type 2 diabetes, baseline interleukin-6 (IL-6) levels may enhance prediction of new-onset obesity-related cancers, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.Mathilde Dahlin Bennetsen, from th

HealthDay 03 September at 03.46 PM

Variable Test Performance Seen With FIT for Advanced Colorectal Neoplasia

Fecal immunochemical tests (FITs) have variable sensitivity and specificity for detecting advanced colorectal neoplasia (ACN), according to a study published online Sept. 3 in the Annals of Internal Medicine.Barcey T. Levy, M.D., Ph.D., from the University of Iowa Carver College of Medicine in Iowa City, and colleagues compared the per

HealthDay 03 September at 03.41 PM

Annual Mammography Screening Tied to Better Outcomes

Annual mammography screening for breast cancer is associated with a lower risk for a late-stage diagnosis and better overall survival across clinical and demographic subgroups, according to a study published online Aug. 21 in the&nbsp;Journal of Clinical Oncology.Margarita L. Zuley, M.D., from University of Pittsburgh, and colleagues e

HealthDay 30 August at 10.42 PM

Living in Rural Areas Tied to Lower Early-Onset Colorectal Cancer Survival

Patients with early-onset colorectal cancer (EO-CRC) living in rural areas have lower five-year survival rates than their urban-dwelling counterparts, according to a research letter published online Aug. 28 in&nbsp;JAMA Network Open.Meng-Han Tsai, Ph.D., from the Georgia Prevention Institute at Augusta University, and colleagues examine

HealthDay 30 August at 10.39 PM

Residing in Poverty Tied to Worse Breast Cancer Outcomes

Women residing in persistently impoverished neighborhoods have worse breast cancer outcomes, according to a study published online Aug. 29 in&nbsp;JAMA Network Open.J.C. Chen, M.D., from The Ohio State University Wexner Medical Center and James Cancer Hospital in Columbus, and colleagues examined persistent neighborhood poverty and brea

HealthDay 30 August at 10.37 PM

FDA Mandates ID Checks for Everyone Younger Than 30 Buying Cigarettes

Retailers will now be required to check the IDs of anyone buying cigarettes who is younger than 30 years of age, the U.S. Food and Drug Administration announced Thursday. The final rule, which wil

HealthDay 28 August at 03.59 PM

Half of Cancer Survivors Face Cancer-Related Financial Hardship

Half of cancer survivors experience cancer-related financial hardship, according to a research letter published online Aug. 20 in&nbsp;JAMA Network Open.Apoorv Dhir, M.D., from the University of Michigan in Ann Arbor, and colleagues estimated the prevalence of financial hardship among cancer survivors across cancer types. The analysi

HealthDay 28 August at 03.46 PM

Treatment of CNS Tumors in Childhood Slows Academic Readiness

Treatment of central nervous system (CNS) tumors in early childhood is associated with slowed development of academic readiness, which predicts distal academic outcomes in reading and math, according to a study published online Aug. 20 in the Journal of the National Cancer Institute.Melanie R. Somekh, Ph.D., from St. Jude Children's

HealthDay 27 August at 09.50 PM

Team-Based Documentation Can Increase Visit Volume, Cut Documentation Time

Physicians who adopt team-based documentation, defined as use of coauthored documentation with another clinical team member, experience increased visit volume and reduced documentation time, according to a study published online Aug. 26 in JAMA Internal Medicine.Nate C. Apathy, Ph.D., from the University of Maryland School of Public He

HealthDay 27 August at 03.46 PM

Radiotherapy Dose to Cardiac Substructures Linked to Arrhythmias

For patients with locally advanced non-small cell lung cancer, radiotherapy dose to discrete cardiac substructures is associated with pathophysiologically distinct arrhythmia classes, according to a study published online in the August issue of JACC: CardioOncology.Katelyn M. Atkins, M.D., Ph.D., from Cedars-Sinai Medical Center in Los

HealthDay 26 August at 02.06 PM

Structural Racism Tied to Elevated Cancer Risk From Traffic Pollutants

Multidimensional structural racism is associated with elevated cancer risk from traffic-related air pollutants, according to a study published online Aug. 26 in Cancer.Emily B. White, M.P.H., and Christine C. Ekenga, Ph.D., M.P.H., from Emory University in Atlanta, examined the relationship between structural racism and estimated cancer

HealthDay 26 August at 02.01 PM

Olaparib Monotherapy Yields Good PSA Response Rates in Prostate Cancer

For men with high-risk biochemically recurrent prostate cancer, olaparib monotherapy yields good prostate-specific antigen (PSA) response rates, especially among those with BRCA2, according to a study published online Aug. 22 in JAMA Oncology.Catherine H. Marshall, M.D., from the Johns Hopkins University School of Medicine in B

HealthDay 23 August at 10.37 PM

Exposure to Tobacco on TV, Streaming Varies by Sociodemographics

Exposure to tobacco on television or streaming platforms differs by key sociodemographic and behavioral characteristics, according to a study published online Aug. 22 in&nbsp;JAMA Network Open.Henry K. Onyeaka, M.D., from Harvard Medical School in Boston, and colleagues examined the prevalence and factors associated with exposure to tob

HealthDay 23 August at 10.11 PM

Cognitive Therapy Improves Mental Health, Quality of Life for Cancer Patients

For cancer patients, cognitive behavioral therapy (CBT) improves mental health and quality-of-life outcomes, according to a systematic review and meta-analysis published online Aug. 21 in Cancer Medicine.Alexander T. Dils, from the Central Michigan University College of Medicine in Saginaw, and colleagues examined the effects of CBT ver

HealthDay 23 August at 03.51 PM

Cognitive Difficulties Tied to Lower Return to Work After Breast Cancer

Return to work two years after a breast cancer diagnosis is associated with higher cognitive speed performance before and after treatment, according to a study published online Aug. 19 in&nbsp;JAMA Network Open.Marie Lange, Ph.D., from Normandie Université UNICAEN in Caen,&nbsp;France, and colleagues examined whether cognition, assessed

HealthDay 23 August at 03.16 PM

Belzutifan Improves Progression-Free Survival in Advanced Renal Cell Cancer

Belzutifan, a hypoxia-inducible factor 2α (HIF-2α) inhibitor, improves progression-free survival and objective responses over everolimus among patients with advanced clear-cell renal cell carcinoma, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.Toni K. Choueiri, M.D., from the Dana-Farber Can

HealthDay 22 August at 04.03 PM

20-Minute Mindful Breathing Intervention Reduces Cancer Pain

A single session of 20-minute mindful breathing is beneficial for reducing cancer pain, according to a study published online Aug. 20 in BMJ Supportive &amp; Palliative Care.Seng Beng Tan, M.B.B.S., from Subang Jaya Medical Centre in Malaysia, and colleagues examined the efficacy of a single session of 20-minute mindful breathing for

HealthDay 22 August at 03.50 PM

Outcomes Similar for Neoadjuvant ICI-Based Therapy, Upfront Surgery for Liver Cancer

Patients treated with neoadjuvant immune checkpoint inhibitor (ICI)-based therapy for hepatocellular carcinoma (HCC) have higher-risk disease features but achieve outcomes comparable to those undergoing upfront surgery, according to a study published online Aug. 15 in Cancer Research Communications.Mari Nakazawa, M.D., from the Johns

HealthDay 22 August at 03.45 PM

Salivary CD44, Total Protein ID Recurrence Risk in Head and Neck Cancer

Elevated salivary levels of CD44 and total protein (TP) can identify head and neck cancer patients with an increased risk for cancer recurrence, according to a study published online Aug. 15 in JAMA Otolaryngology-Head and Neck Surgery.Elizabeth J. Franzmann, M.D., from the University of Miami Health System and Jackson Memorial Hospit

HealthDay 22 August at 03.39 PM

Genetic Subtype, Genomic Alterations Linked to Relapse in Leukemia

Genetic subtype, aneuploidy patterns, and genomic alterations are associated with the risk for relapse in childhood acute lymphoblastic leukemia (ALL), according to a study published online Aug. 9 in the Journal of Clinical Oncology.Ti-Cheng Chang, Ph.D., from St. Jude Children's Research Hospital in Memphis, Tennessee, and colleagues

HealthDay 22 August at 09.33 AM

Americans Have Mixed Feelings About AI in Health Care, Poll Finds

Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the <a href="https://wexnermedical.osu

HealthDay 21 August at 11.00 PM

Benefits of Radiotherapy Last a Decade for Early Breast Cancer

For women with early breast cancer, radiotherapy could prevent ipsilateral breast cancer recurrence for 10 years, but does not provide benefits thereafter, according to a study published online Aug. 7 in The Lancet Oncology.Linda J. Williams, Ph.D., from the University of Edinburgh in the United Kingdom, and colleagues conducted a ra

HealthDay 21 August at 03.31 PM

2020 to 2021 Saw Decline in Life Expectancy for 39 States, Increase for 11

From 2020 to 2021, life expectancy at birth declined for 39 U.S. states and increased for 11 states, according to the Aug. 21 National Vital Statistics Reports, a publication from the National Center for Health Statistics.Elizabeth Arias, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues p

HealthDay 21 August at 03.23 PM

Even Low-Risk Alcohol Consumption Ups Mortality Risk in Older Adults

Even low-risk drinking is associated with higher mortality among older adults, according to a study published online Aug. 12 in&nbsp;JAMA Network Open.Rosario Ortolá, M.D., Ph.D., from Universidad Autónoma de Madrid, and colleagues examined the association between alcohol consumption patterns with 12-year mortality. Analysis included

HealthDay 21 August at 03.21 PM

Life's Essential 8 Is Enhanced With a Psychological Health Measure

A measure of cardiovascular health (CVH) based on Life's Essential 8 (LE8) that is enhanced with a measure of psychological health strongly predicts mortality, according to a study published in the August issue of&nbsp;JACC: Advances.&nbsp;Vanessa T. Dinh, M.P.H., from the Mailman School of Public Health at the Columbia University Ir

HealthDay 20 August at 08.51 PM

Suicide Attempt, Death Up for Spouses of Patients With Cancer

Spouses of patients with cancer have an increased risk for suicide attempt and suicide death, especially during the first year after diagnosis, according to a study published online Aug. 15 in JAMA Oncology.Qianwei Liu, M.D., Ph.D., from the Southern Medical University in Guangzhou, China, and colleagues estimated the risk for suicide

HealthDay 20 August at 04.04 PM

USPSTF: Evidence Still Lacking for Iron Deficiency Screening in Pregnancy

The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to weigh the balance of benefits and harms for recommending screening for iron deficiency and iron deficiency anemia in pregnancy. These findings form the basis of a final recommendation statement published online Aug. 20 in the Journal of the Amer

HealthDay 20 August at 03.50 PM

More Than Half of Older Adults Very Concerned About Medical Costs

Ahead of the 2024 election, more than half of older U.S. adults report being very concerned about the costs of medical care, according to a research letter published online Aug. 14 in the&nbsp;Journal of the American Medical Association.John Z. Ayanian, M.D., from the University of Michigan in Ann Arbor, and colleagues surveyed a natio

HealthDay 19 August at 09.57 PM

Alternative Criteria Can ID High-Benefit Groups for Lung Cancer Screening

Simple alternative criteria for lung cancer screening (LCS) can identify high-benefit groups, especially among certain racial and ethnic-minority groups, according to a study published online Aug. 20 in the Annals of Internal Medicine.Noting that the U.S. Preventive Services Task Force (USPSTF) recommendation for LCS may exclude some hi

HealthDay 19 August at 09.55 PM

Poor Psychological Outcomes Seen for Patients With Rare Cancers

Patients with rare cancers have poor psychological outcomes, according to a review and meta-analysis published in the June issue of eClinicalMedicine.Chen Ee Low, from the School of Medicine at the National University of Singapore, and colleagues conducted a systematic review to examine the psychological outcomes of patients with rare c

HealthDay 19 August at 03.27 PM

High Health Care Utilization, Poor Survival Seen for Over 70s With AML

Older patients with acute myeloid leukemia (AML) have high health care utilization and poor survival outcomes, according to a study published online Aug. 13 in Hematological Oncology.Marie Anne-Catherine Neumann, Ph.D., from the University of Cologne in Germany, and colleagues conducted an analysis of 107 consecutive patients with newly

HealthDay 19 August at 03.21 PM

Patients Have to Travel Farther for Facilities With Breast MRI, Ultrasound Than for Mammography

The geographic distance to facilities offering breast magnetic resonance imaging (MRI) or ultrasound is further than to those offering mammography, according to a study published online Aug. 12 in the American Journal of Preventive Medicine.Eric W. Christensen, Ph.D., from the Neiman Health Policy Institute in Reston, Virginia, and coll

HealthDay 16 August at 09.19 PM

Acceptable Liver Transplant Outcomes Seen After ICI Therapy for Liver Cancer

For patients with hepatocellular carcinoma (HCC), immune checkpoint inhibitor (ICI) use prior to liver transplant (LT) does not worsen outcomes, according to research published online July 10 in the Journal of Hepatology.Mohammad Saeid Rezaee-Zavareh, from the Middle East Liver Diseases Center in Tehran, Iran, and colleagues summarized

HealthDay 16 August at 03.13 PM

Mental Health Utilization Increased Around Time of Prostate Cancer Diagnosis

There is an increase in psychotropic medication use and mental health service use around the time of prostate cancer diagnosis, according to a study published online July 3 in&nbsp;Psycho-Oncology.Tenaw Tiruye, Ph.D., from the University of South Australia in Adelaide, and colleagues used registry data linked to Pharmaceutical Benefits

HealthDay 16 August at 02.59 PM

Symptom-Triggered Testing Can ID Low Disease Burden in Ovarian Cancer

Symptom-triggered testing can identify women with high-grade serous ovarian cancer with low disease burden, according to a study published online Aug. 13 in the International Journal of Gynecological Cancer.Fong Lien Audrey Kwong, from The Pan-Birmingham Gynaecological Cancer Centre at the Sandwell and West Birmingham NHS Trust in the U

HealthDay 15 August at 03.59 PM

Iron Deficiency Common, Often Persistent

Iron deficiency (ID) is common in an American statewide health system, and the time to resolution is prolonged, according to a study published online Aug. 15 in Blood Advances.Jacob C. Cogan, M.D., from the University of Minnesota in Minneapolis, and colleagues conducted a retrospective review of electronic medical record data from a

HealthDay 15 August at 11.36 AM

New Deals Will Cut Medicare Costs for Expensive Drugs

The Biden administration said Thursday that it has signed deals with drug companies that will lower the prices on 10 of the most popular and expensive drugs used by American seniors.Taxpayers should save $6 billion because of the new prices, while seniors using Medicare could save roughly $1.5 billion on their medications, the U.S. Centers for

HealthDay 14 August at 10.24 PM

Breast Cancer Screening Attendance Helps Boost Other Cancer Screenings

Offering self-sampling kits to women overdue for cervical cancer (CC) or colorectal cancer (CRC) screening when they attend breast cancer (BC) screening can result in increased screening participation, according to a study published online Aug. 13 in&nbsp;PLOS Medicine.Anne Dorte Lerche Helgestad, from Randers Regional Hospital in De

HealthDay 14 August at 03.45 PM

Clinicians Are Interested in Climate Change Education

Most clinicians show positive attitudes toward education in climate change, according to a study published online Aug. 8 in&nbsp;JAMA Network Open.Wynne Armand, M.D., from the Center for the Environment and Health at Massachusetts General Hospital in Boston, and colleagues evaluated whether a quality incentive program measure for cli

HealthDay 14 August at 03.40 PM

Baseline MRI PI-RADS Linked to Biopsy Reclassification in Prostate Cancer

The baseline magnetic resonance imaging (MRI) Prostate Imaging Reporting and Data System (PI-RADS) score is associated with biopsy reclassification among men with prostate cancer undergoing active surveillance (AS), according to a study published online June 25 in The Journal of Urology.Kiran R. Nandalur, M.D., from William Beaumont

HealthDay 14 August at 03.37 PM

Sacituzumab Govitecan Shows Promise in Advanced Endometrial Cancer

For patients with advanced endometrial cancer (EC), sacituzumab govitecan (SG), a trophoblast cell-surface antigen 2 (Trop-2)-directed antibody-drug conjugate, shows encouraging efficacy, according to a phase 2 study published online July 31 in the Journal of Clinical Oncology.Alessandro D. Santin, M.D., from the Yale School of Medic

HealthDay 13 August at 03.52 PM

Nicotine Analogue Concentrations Deviate From Labels

There are discrepancies between labeled and measured concentrations of nicotine analogues in electronic cigarettes and e-cigarette liquids, according to a research letter published online Aug. 7 in the&nbsp;Journal of the American Medical Association.Hanno C. Erythropel, Ph.D., from Yale University in New Haven, Connecticut, and collea

HealthDay 12 August at 04.06 PM

Substantial Disparities Seen in Cancer Cases, Deaths Among Men

There are substantial disparities in cancer cases and deaths among men, which are projected to widen by 2050, according to a study published online Aug. 12 in Cancer.Habtamu Mellie Bizuayehu, Ph.D., from the University of Queensland in Brisbane, Australia, and colleagues analyzed 30 cancer types among men in 2022 using GLOBOCAN estimate

HealthDay 12 August at 03.50 PM

Cannabis-Related Disorder Linked to Risk for Head and Neck Cancer

Cannabis-related disorder is associated with an increased rate of head and neck cancer (HNC), according to a study published online Aug. 8 in JAMA Otolaryngology-Head &amp; Neck Surgery.Tyler J. Gallagher, from the Keck School of Medicine of the University of Southern California in Los Angeles, and colleagues examined the clinical assoc

HealthDay 12 August at 03.47 PM

Gene Expression Signature Predicts Immune-Related Adverse Events in Melanoma Patients

A gene expression signature in peripheral CD4+ T-cells can predict severe immune-related adverse events (irAEs) among melanoma patients treated with ipilimumab/nivolumab, according to a study published online Aug. 8 in Clinical Cancer Research.Kelsey R. Monson, Ph.D., from the Perlmutter Cancer Center at NYU Langone Health in

HealthDay 09 August at 08.08 PM

Rheumatoid Arthritis Tied to Higher Risk for Lung Cancer

Rheumatoid arthritis (RA) is associated with a significantly increased risk for lung cancer, according to a study published online July 28 in&nbsp;Arthritis &amp; Rheumatology.Rebecca T. Brooks, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues evaluated lung cancer risk in people with RA and RA-interstitial lung disease

HealthDay 09 August at 03.40 PM

FDA Approves Voranigo for Grade 2 Astrocytoma or Oligodendroglioma

The U.S. Food and Drug Administration has approved Voranigo (vorasidenib) for grade 2 astrocytoma or oligodendroglioma with a susceptible mutation.The isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor is approved for adult and pediatric patients ages 12 years and older with grade 2 astrocytoma or oligodendroglioma

HealthDay 09 August at 03.37 PM

Racial Differences Identified in Frequency of Biopsy for Psoriasis

There are racial differences in the frequency of skin biopsy for psoriasis, indicating diagnostic uncertainty, according to a research letter published online Aug. 7 in JAMA Dermatology.Fahad Ahmed, from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and colleagues conducted a cross-sectional study inv

HealthDay 09 August at 03.21 PM

Blood Test Results Can Enhance Assessment of Cancer Risk

The assessment of cancer risk based on symptoms, age, and sex can be enhanced by considering information from common blood test results among patients presenting with nonspecific abdominal symptoms, according to a study published online July 30 in PLOS Medicine.Meena Rafiq, M.D., Ph.D., from University College London, and colleagues quan

HealthDay 08 August at 11.00 PM

CDC Presents Provisional Mortality Data for 2023 in the United States

In 2023, there was a provisional total of 3,090,582 deaths in the United States, according to research published in the Aug. 8 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Farid B. Ahmad, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues

HealthDay 07 August at 11.01 PM

Nipocalimab Can Delay, Prevent Anemia, Intrauterine Transfusion

For pregnancies at high risk for early-onset severe hemolytic disease of the fetus and newborn (HDFN), intravenous nipocalimab can delay or prevent fetal anemia or intrauterine transfusions, according to a study published online Aug. 7 in the New England Journal of Medicine.Kenneth J. Moise Jr., M.D., from Dell Medical School at the U

HealthDay 07 August at 10.55 PM

FDA Approves Darzalex Faspro for Treating Multiple Myeloma

The U.S. Food and Drug Administration has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj) in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation in patients with newly diagnosed multiple myeloma (MM) who are eligible for an autologous stem cell transplant (ASCT).The approval was ba

HealthDay 07 August at 03.26 PM

Pharmacogenomic Score Can Personalize Treatment of Leukemia in Children

For pediatric patients with acute myeloid leukemia (AML), a pharmacogenomics-based 10 single nucleotide polymorphism cytarabine (Ara-C) score (ACS10) can be used to tailor induction regimens, yielding improved outcomes, according to a study published online July 30 in Clinical Cancer Research.Noting that low ACS10 has been shown to be

HealthDay 07 August at 03.20 PM

Preoperative IV Iron Treatment Better for Iron Deficiency Anemia

For patients with preoperative iron deficiency anemia (IDA), intravenous (IV) iron treatment is associated with a significant reduction in 30-day postoperative mortality and morbidity compared with red blood cell (RBC) transfusion, according to research published online July 22 in Anesthesia &amp; Analgesia.Una E. Choi, from the Johns

HealthDay 07 August at 03.10 PM

Complex Interaction Seen Between Social Determinants of Health, Mortality

There is a complex interaction among social determinants of health with mortality risk, but a scoring system is able to identify subgroups with a high risk for mortality, according to a study published online Aug. 5 in BMJ Open.Marie-Pier Bergeron-Boucher, Ph.D., from the Interdisciplinary Centre on Population Dynamics at Syddansk Uni

HealthDay 07 August at 11.45 AM

Red Cross Issues Blood Shortage Alert as Summer Heat Cuts Donations

This summer's blistering temperatures have helped prompt an&nbsp;emergency blood shortage, the American Red Cross has warned.Heat waves affected almost 100 blood drives last month, either by hurting turnout or forcing the events to be canceled. Since July 1, the national blood supply has fallen by more than 25%, the organization said in a <a h

HealthDay 06 August at 11.01 PM

FDA Approves Tecelra as First Gene Therapy for Synovial Sarcoma

The U.S. Food and Drug Administration has approved Tecelra (afamitresgene autoleucel), a gene therapy for the treatment of adults with unresectable or metastatic synovial sarcoma.Specifically, the approval is for adults who have received prior chemotherapy, are HLA-A*02:01P, -A*02:02P, -A*02:03P, or -A*02:06P positive, and have a tumor that expr

HealthDay 06 August at 03.47 PM

Aspirin-Linked Reduction in CRC Risk Varies With Lifestyle Score

Aspirin use is associated with a reduction in colorectal cancer (CRC) risk, with the greatest reduction seen among those with the unhealthiest lifestyle scores, according to a study published online Aug. 1 in JAMA Oncology.Daniel R. Sikavi, M.D., from Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues ex

HealthDay 05 August at 10.22 PM

Estimated U.S. Annual Cost of Initial Cancer Screening $43 Billion in 2021

In 2021, the estimated total health care costs for initial cancer screening were $43 billion in the United States, according to a study published online Aug. 6 in the Annals of Internal Medicine.Michael T. Halpern, M.D., Ph.D., from the National Cancer Institute in Bethesda, Maryland, and colleagues estimated the annual cost of initial c

HealthDay 05 August at 10.16 PM

Mentorship Program in Classical Hematology Facilitates Career Development

A mentorship pilot program in classical hematology can facilitate career development and improve retention in the field, according to a study published online Aug. 1 in Blood Advances.Noting that there is a lack of mentorship opportunities within classical hematology versus medical oncology, Zoya Qureshy, M.D., from the University of Cal

HealthDay 05 August at 04.00 PM

2007 to 2020 Saw Continuous Decrease in Cervical Cancer in Younger Women

For individuals younger than 25 years, the incidence of cervical intraepithelial neoplasia (CIN) decreased continuously from 2007 through 2020, according to a research letter published online July 25 in JAMA Oncology.Rachael Adcock, Ph.D., from the University of New Mexico Center for HPV Prevention in Albuquerque, and colleagues updated

HealthDay 01 August at 09.52 PM

Incidence of Many Cancers Increasing Among Younger Generations

Younger birth cohorts have an increased incidence of many common cancer types, according to a study published in the August issue of The Lancet Public Health.Hyuna Sung, Ph.D., from the American Cancer Society in Atlanta, and colleagues obtained incidence data for 34 types of cancer and mortality data for 25 types of cancer for individ

HealthDay 01 August at 03.56 PM

Smoking + Early Menopause Increases Risk for Lung Disease, Poor Outcomes

Among smokers, early menopause is associated with an increased risk for most lung diseases and poor outcomes, according to a study published online June 13 in&nbsp;Thorax.Xiaochun Gai, M.B.B.S., from the University of New Mexico School of Medicine in Albuquerque, and colleagues assessed whether early menopause due to surgery affects lu

HealthDay 01 August at 03.53 PM

Mortality Risk High for Some Gleason Grade 1 Prostate Cancer Patients

For patients with Gleason Grade Group (GGG) 1 prostate cancer (PC), those with percentage positive biopsies (PPB) &gt;50 percent or prostate-specific antigen (PSA) &gt;20 ng/mL have a significantly increased risk for adverse outcomes, according to a study published online July 2 in European Urology Oncology.Derya Tilki, M.D., from Univ

HealthDay 01 August at 09.47 AM

Most Americans Don't Know About Lung Cancer Screening: Survey

People who've had a history of smoking can get lung cancer spotted early -- when it's most treatable -- through annual CT screening.Unfortunately, most Americans polled in a new survey didn't know this potentially lifesaving screen exists.“The survey

HealthDay 31 July at 10.54 PM

Study Examines Trends in Esophageal Cancer Disparities Over Time

From 1999 to 2020, age-adjusted esophageal cancer mortality decreased among Black adults but stabilized among White adults, reducing the racial mortality gap, according to a study published online July 24 in the Journal of Gastroenterology and Hepatology.Chun-Wei Pan, M.D., from the John H. Stroger, Jr., Hospital of Cook County in Ch

HealthDay 31 July at 04.04 PM

Common Genetic Risk Seen for Primary Ovarian Insufficiency, Cancer

There seems to be a common genetic risk for primary ovarian insufficiency (POI) and reproductive cancer risk, according to a study published online July 12 in the Journal of Clinical Endocrinology &amp; Metabolism.Kristina Allen-Brady, Ph.D., M.P.H., from the Huntsman Can

HealthDay 31 July at 03.53 PM

Cholesterol Absorption Inhibitors May Cut Risk for Liver Cancer

The use of cholesterol absorption inhibitors is associated with a reduced risk for liver cancer, according to a study published online July 29 in&nbsp;Cancer.Shahriar A. Zamani, Ph.D., from the National Cancer Institute at the National Institutes of Health in Rockville, Maryland, and colleagues examined the risk for liver cancer for

HealthDay 30 July at 08.59 PM

CDC: Despite Wanting to Quit, Only 8.8 Percent Quit Smoking in 2022

Although about two-thirds of U.S. adults who smoked wanted to quit, only 8.8 percent of smokers quit in 2022, according to research published in the July 25 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Brenna VanFrank, M.D., from the CDC in Atlanta, and colleagues used 2022 National

HealthDay 30 July at 08.56 PM

Being at Eye Level May Benefit Clinician-Patient Interaction

Eye-level communication by clinicians appears beneficial compared with standing at the bedside of inpatients, according to a review published online July 17 in the&nbsp;Journal of General Internal Medicine.Nathan Houchens, M.D., from the University of Michigan Medical School in Ann Arbor, and colleagues conducted a systematic literatur

HealthDay 30 July at 03.43 PM

Toxicities Rare After Two Weeks of CAR T-Cell Therapy Infusion

New-onset cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are rare beyond two weeks following infusion of CD19-directed chimeric antigen receptor T (CAR T)-cell therapies, according to a study published online July 23 in Blood Advances.Noting that the U.S. Food and Drug Administration

HealthDay 30 July at 03.29 PM

Incidence of Specific, All Cancers Increased With Pesticide Use

Pesticide usage is associated with an increased incidence of cancer, according to a study published online July 25 in Frontiers in Cancer Control and Society.Jacob Gerken, D.O., from the Rocky Vista University College of Osteopathic Medicine in Englewood, Colorado, and colleagues examined the relationship between pesticides and cancer

HealthDay 29 July at 03.34 PM

Risk of Contralateral Breast Cancer Lower With Bilateral Mastectomy

For women with unilateral breast cancer, the risk of contralateral breast cancer is lower after bilateral mastectomy, but mortality rates are similar to those after lumpectomy or unilateral mastectomy, according to a study published online July 25 in JAMA Oncology.Vasily Giannakeas, Ph.D., M.P.H., from the Women's College Hospital in To

HealthDay 29 July at 03.30 PM

Blinatumomab + Chemo Ups Survival in B-Cell Precursor Acute Lymphoblastic Leukemia

For adult patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) who have measurable residual disease (MRD)-negative remission, blinatumomab in addition to consolidation chemotherapy is associated with improved overall survival, according to a study published in the July 25 issue of the New England Journal of Medicine.Mar

HealthDay 29 July at 03.30 PM

Study Looks at Effects of Reducing Intake of Processed Meat, Unprocessed Red Meat

Reductions in processed meat and unprocessed red meat consumption could result in fewer occurrences of type 2 diabetes, cardiovascular disease, colorectal cancer, and all-cause deaths, according to a study published in the July issue of The Lancet Planetary Health.Joe Kennedy, Ph.D., from the University of Edinburgh in the United Kingdo

HealthDay 29 July at 01.54 PM

FDA Approves Another Blood Test for Colon Cancer Screening

The U.S. Food and Drug Administration on Monday approved a new blood test that can spot colon cancer.In late May, an FDA advisory panel had voted 7-2 that the benefits outweigh the risks when using the Guardant Health's Shield test for&n

HealthDay 26 July at 06.26 PM

Prostate Cancer Outcomes Comparable for Transgender Women, Cisgender Men

Most prostate cancer outcomes do not differ significantly between transgender women (TGW) and cisgender (CG) men, including prostate cancer-specific mortality, according to a study published online July 21 in Cancer.Margaret Meagher, M.D., from the University of California San Diego School of Medicine in La Jolla, and colleagues compare

HealthDay 25 July at 03.28 PM

Socioeconomic Status of Stem Cell Donor Affects Recipient Health Outcomes

Hematopoietic cell transplantation (HCT) donors' socioeconomic status (SES) affects recipients' health outcomes, according to a study published online July 15 in PNAS.Lucie M. Turcotte, M.D., M.P.H., from the University of Minnesota Medical School in Minneapolis, and colleagues examined the cellular transplantability of SES-associated

HealthDay 25 July at 03.23 PM

Exposure to Hydroxyurea Does Not Impact Ovarian Reserve in Sickle Cell

For girls and young women with sickle cell disease (SCD), exposure to hydroxyurea does not reduce ovarian reserve, according to a study published online July 18 in Blood Advances.Tamara Diesch-Furlanetto, Ph.D., from the University of Basel Children's Hospital in Switzerland, and colleagues counted follicles and categorized them based

HealthDay 25 July at 03.15 PM

Nudge in EHR Can Reduce Unnecessary Sentinel Lymph Node Biopsy

A nudge intervention in the electronic health record (EHR) targeting surgeons can reduce sentinel lymph node biopsy (SLNB) among women who meet the Choosing Wisely criteria for SLNB omission, according to a study published online July 17 in JAMA Surgery.Neil Carleton, Ph.D., from UPMC Hillman Cancer Center in Pittsburgh, and colleague

HealthDay 25 July at 03.13 PM

Hormone-Modulating Therapy May Reduce Dementia Risk in Breast Cancer

For women with breast cancer, hormone-modulating therapy (HMT) is associated with reduced risk of Alzheimer disease and related dementias (ADRD), according to a study published online July 16 in JAMA Network Open.Chao Cai, Ph.D., from the University of South Carolina in Columbia, and colleagues examined the association between HMT for

HealthDay 23 July at 10.25 PM

Disparities Persist in Postmastectomy Reconstruction

Postmastectomy reconstruction (PMR) rates among American Indian/Alaska Native (AI/AN) women with breast cancer increased from 2004 to 2017, but remain significantly lower than rates among non-Hispanic White (NHW) women, according to a study published in the July issue of&nbsp;Plastic and Reconstructive Surgery.McKenzie J. White, M.D.,

HealthDay 23 July at 04.00 PM

Chemo Tied to Gut Microbiome Changes and Associated Cognitive Decline

Gut microbiome change is associated with cognitive decline during chemotherapy for patients with breast cancer, according to a study published online in the August issue of Brain, Behavior, and Immunity.Lauren D. Otto-Dobos, Ph.D., from the Institute for Behavioral Medicine Research at The Ohio State University in Columbus, and colleag

HealthDay 23 July at 03.50 PM

Many Breast Cancer Survivors With Indications for Genetic Testing Do Not Receive It

Many breast cancer survivors with indications for genetic counseling and testing do not receive it, according to a study published online July 15 in the&nbsp;Journal of Clinical Oncology.Steven J. Katz, M.D., from the University of Michigan in Ann Arbor, and colleagues examined receipt of genetic testing and communication with relative

HealthDay 23 July at 03.45 PM

FIT Screening Cuts Risk of Death From Colorectal Cancer

Screening with fecal immunochemical tests (FITs) lowers the risk of dying from colorectal cancer (CRC), according to a study published online July 19 in&nbsp;JAMA Network Open.Chyke A. Doubeni, M.D., from The Ohio State University College of Medicine in Columbus, and colleagues evaluated whether FIT screening is associated with a lower

HealthDay 22 July at 03.40 PM

AI-Assisted Model Improves Diagnosis of Solid Lesions in Pancreas

A joint artificial intelligence (AI)-assisted model integrating clinical information and endoscopic ultrasonographic (EUS) images improves diagnosis of solid lesions in the pancreas, according to a study published online July 19 in JAMA Network Open.Haochen Cui, M.D., from Tongji Hospital in Wuhan, China, and colleagues developed a mult

HealthDay 22 July at 03.34 PM

Clinical Report Addresses Management of Sickle Cell Disease in Children, Teens

Management of children and adolescents with sickle cell disease (SCD) requires comprehensive care from a pediatric primary care provider and a multidisciplinary team, according to a clinical report published online July 22 in Pediatrics.Amber M. Yates, M.D., from the Baylor College of Medicine and Texas Children's Hospital in Houston, a

HealthDay 22 July at 03.15 PM

Neuromuscular Training Cuts Onset of Chemo-Induced Peripheral Neuropathy

Neuromuscular training reduces the onset of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online July 1 in JAMA Internal Medicine.Fiona Streckmann, Ph.D., from the University of Basel in Switzerland, and colleagues examined whether sensorimotor training (SMT) and whole-body vibration (WBV) training re

HealthDay 19 July at 10.52 PM

Prevalence of Skin Cancer Varies for Sexual Minority, Heterosexual Adults

With respect to their lifetime prevalence of skin cancer, sexual minority (SM) adults differ across racial and ethnic groups and among males and females, according to a study published online July 17 in JAMA Dermatology.Katelyn J. Rypka, from the University of Minnesota in Minneapolis, and colleagues examined differences in the lifetime

HealthDay 19 July at 04.13 PM

Efanesoctocog Alfa Prophylaxis Beneficial for Children With Hemophilia A

For children with severe hemophilia A, once-weekly prophylaxis with efanesoctocog alfa is associated with high sustained factor VIII activity, resulting in effective prevention of bleeding, according to a study published in the July 18 issue of the New England Journal of Medicine.Lynn Malec, M.D., from the Versiti Blood Research Institu

HealthDay 19 July at 04.01 PM

Neighborhood Disadvantage Metrics Tied to Stress Genes in Prostate Cancer

Expression of several stress-related genes in prostate tumors is elevated among men residing in disadvantaged neighborhoods, according to a study published online July 12 in JAMA Network Open.Joseph Boyle, Ph.D., from Virginia Commonwealth University in Richmond, and colleagues examined whether several neighborhood disadvantage metrics

HealthDay 19 July at 10.37 AM

FDA Allows Marketing of Vuse Tobacco-Flavored Vapes

The U.S. Food and Drug Administration on Thursday authorized the sale of the country's best-selling e-cigarette.The agency's <a href="https://www.fda.gov/tobacco-products/ctp-newsroom/fda-authorizes-marketing-vuse-alto-tobacco-flavored-e-cigarette-pods-and-accompanying-power-unit?utm_campaign=ctp-pmta&amp;utm_content=statement&amp;utm_medium=ema

HealthDay 18 July at 10.17 PM

Risk for Ovarian Cancer Increased for Women With Endometriosis

Women with endometriosis have an increased risk of ovarian cancer, with the highest risk seen for women with deep infiltrating endometriosis and/or ovarian endometriomas, according to a study published online July 17 in the Journal of the American Medical Association.Mollie E. Barnard, Sc.D., from the University of Utah in Salt Lake C

HealthDay 17 July at 03.36 PM

Active Commuters Have Lower Risks for Morbidity, Mortality

Active commuters who cycle or walk to work have lower risks for morbidity and mortality, according to a study published online July 16 in BMJ Public Health.Catherine Friel, from the University of Glasgow in the United Kingdom, and colleagues examined prospective associations with multiple health outcomes over 18 years for pedestrians

HealthDay 17 July at 03.19 PM

Ophthalmologic Manifestations of Acute Leukemia Are Heterogeneous

Ophthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a study published online July 10 in the Annals of Hematology.Dina N. Laimon, M.D., from Mansoura University in Egypt, and colleagues examined the incidence of different ophthalmological manifestations in n

HealthDay 15 July at 10.09 PM

Some Women in Their 40s Prefer to Delay Breast Cancer Screening

A considerable proportion of women aged 39 to 49 years prefer to delay breast cancer screening, especially after a decision aid (DA) intervention, according to a study published online July 16 in the Annals of Internal Medicine.Laura D. Scherer, Ph.D., from the University of Colorado School of Medicine in Aurora, and colleagues examined

HealthDay 15 July at 02.57 PM

Modifiable Risk Factors Account for Many Cancer Cases, Deaths

An estimated 40.0 percent of all incident cancer cases and 44.0 percent of cancer deaths are attributable to potentially modifiable risk factors among U.S. adults aged 30 years and older, according to a study published online July 11 in CA: A Cancer Journal for Clinicians.Farhad Islami, M.D., Ph.D., from the American Cancer Society in A

HealthDay 15 July at 02.54 PM

Successful Pregnancy Possible for Stem Cell Transplant Recipients

Successful pregnancies are feasible for female allogeneic hematopoietic cell transplant (alloHCT) recipients, with most pregnancies occurring spontaneously, according to a study published online July 15 in Blood.Katja Sockel, M.D., from the Technical University Dresden in Germany, and colleagues examined pregnancy and birth rates in a c

HealthDay 15 July at 02.51 PM

Out-of-Pocket Costs Considerable, Increasing for Prostate Cancer Diagnostic Testing

For patients with private insurance undergoing diagnostic testing after prostate-specific antigen (PSA)-based screening, out-of-pocket costs are considerable and increased from 2010 to 2020, according to a study published online July 15 in Cancer.Arnav Srivastava, M.D., M.P.H., from the University of Michigan in Ann Arbor, and colleague

HealthDay 15 July at 10.22 AM

Late Cancer Diagnosis Biggest Health Concern for Most, Poll Shows

When it comes to health worries, cancer leads the way, a&nbsp;new poll shows.The University of Cambridge poll included 2,000 adults who said their biggest concern is getting diagnosed with cancer when it's too late to treat it. Seven in 10 respondents have that fear, while 52% fret about the impact of a cancer diagnosis on loved ones."Can

HealthDay 12 July at 10.21 PM

More Women Than Men Experience Nonphysical Violence in Health Care Workforce

Women in the health care workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study published online July 2 in PLOS Global Public Health.Sioban Nelson, R.N., Ph.D., from the University of Toronto, and colleagues conducted a scopin

HealthDay 12 July at 12.36 PM

New Report Calls for More Research on Women's Health Issues

A new report finds research is sorely lacking on how chronic illnesses affect women, and it urged government agencies to do more to investigate how these diseases strike women differently.The National Academies of Sciences, Engineering and Medicine <a href="https://nap.nationalacademies.org/catalog/27757/advancing-research-on-chronic-conditions-

HealthDay 11 July at 04.07 PM

18F-PSMA-1007 PET/CT Superior to MRI for Staging Prostate Cancer

For men undergoing locoregional staging of prostate cancer, fluorine-18 prostate-specific membrane antigen-1007 positron emission tomography/computed tomography (18F-PSMA-1007 PET/CT) is superior to multiparametric magnetic resonance imaging (MRI), according to a study published online July 1 in JAMA Oncology to coincide with the

HealthDay 11 July at 04.04 PM

GLP-1 RAs May Reduce Risk for Some Obesity-Linked Cancers Versus Insulin in T2D

For patients with type 2 diabetes (T2D), glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are associated with a reduced risk for 10 of 13 obesity-associated cancers (OACs) compared with insulin, according to a study published online July 5 in JAMA Network Open.Lindsey Wang, from Case Western Reserve University School of Medicine

HealthDay 11 July at 03.56 PM

Higher Mortality, Less Improvement Seen for Rural Residents With Head, Neck Cancer

Compared with their urban counterparts, rural residents with head and neck cancer (HNC) have higher mortality rates and less annual improvement, according to a research letter published online June 27 in JAMA Otolaryngology-Head &amp; Neck Surgery.Nino Balanchivadze, M.D., from the Virginia Oncology Associates in Norfolk, and colleagu

HealthDay 10 July at 10.29 PM

Mediterranean Diet Adherence Tied to Lower Mortality for Cancer Survivors

For cancer survivors, higher adherence to a traditional Mediterranean diet (MD) is associated with a reduction in all-cause mortality, specifically cardiovascular mortality, according to a research letter published online July 2 in JACC: CardioOncology.Marialaura Bonaccio, Ph.D., from IRCCS Neuromed in Pozzilli, Italy, and colleagues

HealthDay 10 July at 03.58 PM

Study Looks at Impact of Incentivizing Smoking Cessation in Addition to Usual Care

Incentivizing smoking cessation increases smoking cessation through 12 weeks, but not at 26 weeks, when missing data are treated as smoking, according to a study published online July 2 in JAMA Network Open.Darla E. Kendzor, Ph.D., from the University of Oklahoma Health Sciences Center in Oklahoma City, and colleagues randomly assign

HealthDay 10 July at 03.55 PM

Transvaginal Ultrasound Triage Strategy for Endometrial Cancer Not Reliable for Black Women at Risk

For Black adults at risk for endometrial cancer (EC), a transvaginal ultrasonography triage strategy is not reliable, according to a study published online June 27 in JAMA Oncology.Kemi M. Doll, M.D., from the University of Washington in Seattle, and colleagues examined false-negative probability using ultrasonography-measured endome

HealthDay 09 July at 03.54 PM

Intensity-Modulated Radiotherapy Recommended for Locally Advanced Lung Cancer

Intensity-modulated radiotherapy (IMRT) is recommended for locally advanced non-small cell lung cancer (NSCLC) and appears to have good long-term outcomes, according to a study published online June 27 in JAMA Oncology.Stephen G. Chun, M.D., from The University of Texas MD Anderson Cancer Center in Houston, and colleagues compared long-

HealthDay 09 July at 03.48 PM

PSA Levels Very Low Among Transgender Women Receiving Estrogen

For transgender women receiving estrogen, the median prostate-specific antigen (PSA) level is 0.02 ng/mL, according to a research letter published online June 26 in the Journal of the American Medical Association.Farnoosh Nik-Ahd, M.D., from the University of California, San Francisco, and colleagues determined PSA values among a nation

HealthDay 09 July at 03.45 PM

Rural Residents Continue to Have Higher Odds of Skin Cancer

Urban-rural disparities in skin cancer prevalence continue to persist, according to a study published in the June issue of the&nbsp;Journal of Drugs in Dermatology.Rachel R. Lin, from the University of Miami Miller School of Medicine, and colleagues used data from the Behavior Risk Factor Surveillance Survey (2018 to 2021) to compare th

HealthDay 09 July at 03.39 PM

Racial Differences Seen in Epigenetic Age Acceleration in Childhood Cancer Survivors

For childhood cancer survivors, there are racial and ethnic disparities in epigenetic age acceleration (EAA), which are partially mediated by social determinants of health (SDOH), according to a study published online July 2 in JAMA Network Open.Cheng Chen, from The Fourth Affiliated Hospital of Soochow University in Suzhou, China, and

HealthDay 09 July at 03.29 PM

E-Cigarette Use Linked to Lower Use of Lung Cancer Screening

Electronic cigarette use is associated with a lower use of lung cancer screening (LCS), according to a research letter published online July 2 in JAMA Network Open.Qian Wang, M.D., M.P.H., from the University Hospitals Seidman Cancer Center in Cleveland, and colleagues examined the association between e-cigarette use and LCS uptake in a

HealthDay 08 July at 03.26 PM

Tisotumab Vedotin Efficacious for Recurrent Cervical Cancer

Second- or third-line treatment with tisotumab vedotin is efficacious for patients with recurrent cervical cancer, according to a study published in the July 4 issue of the New England Journal of Medicine.Ignace Vergote, M.D., Ph.D., from Universitaire Ziekenhuizen Leuven in Belgium, and colleagues conducted a phase 3, multinational, ope

HealthDay 08 July at 02.52 PM

Granting Waiver for Cancer Treatment Does Not Affect Safety, Efficacy Outcomes

In a trial involving patients with therapy-refractory cancer treated with approved targeted or immunotherapies, matched to their tumor molecular profile but outside their registered indications, those for whom a waiver was granted had similar serious adverse event rates and clinical benefit rates as those who did not receive a waiver, according to a stu

HealthDay 05 July at 02.26 PM

Postpandemic Physician Revenue Recovery Varies by Specialty, Practice Type

Pandemic-associated physician revenue recovery in 2021 and 2022 varied by specialty and practice type, according to a study published in the July issue of&nbsp;Health Affairs.Ravi B. Parikh, M.D., from the University of Pennsylvania in Philadelphia, and colleagues assessed pandemic-related impact on physician revenue (2020 to 2022) and h

HealthDay 03 July at 03.01 PM

AI-Assisted Contours Superior to Cognitively Defined Prostate Cancer Contours

Artificial intelligence (AI)-assisted definition of prostate cancer contours reduces underestimation of the extent of prostate cancer, according to a study published in the July issue of The Journal of Urology.Sakina Mohammed Mota, Ph.D., from Avenda Health, and colleagues compared physicians' performance using AI versus stan

HealthDay 03 July at 02.59 PM

Vaginal Cancer Incidence Increasing Globally

The incidence of vaginal cancer is increasing globally, according to a study published online June 25 in BJOG: An International Journal of Obstetrics and Gynaecology.Junjie Huang, from the Chinese University of Hong Kong, and colleagues investigated the incidence, risk factors, and trends for vaginal cancer using dat

HealthDay 02 July at 04.01 PM

Mean Cost of Bringing New Drug to U.S. Market Is $879.3 Million

The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in&nbsp;JAMA Network Open.Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in Lexington, Massachusetts, and colleagues ass

HealthDay 02 July at 03.57 PM

Perioperative Chemo Improves Progression-Free Survival in Pancreatic Cancer

For patients with resectable pancreatic ductal adenocarcinoma (PDAC), the 12-month progression-free survival (PFS) may be increased with neoadjuvant modified 5-fluorouracil, leucovorin, oxaliplatin, and irinotecan (mFOLFIRINOX), according to a study published online June 20 in JAMA Oncology.Michael Cecchini, M.D., from the Yale Universi

HealthDay 02 July at 03.19 PM

Nudging Both Clinicians, Patients May Increase Serious Illness Conversations

Combining clinician- and patient-directed nudges may help to promote serious illness conversations (SICs) in cancer care, according to a study published online July 1 in JAMA Network Open.Samuel U. Takvorian, M.D., from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and colleagues randomly assigned cl

HealthDay 01 July at 10.10 PM

Racial Differences Seen in Financial Hardship Among Older Cancer Survivors

Income and area-level disadvantage are the largest contributors to racial differences in financial hardship among older U.S. adults with cancer, according to a study published online June 18 in&nbsp;Cancer.Elizabeth S. Davis, M.S.P.H., from Boston University, and colleagues conducted a survey to assess financial hardship among older adul

HealthDay 01 July at 03.33 PM

ISTH Issues Clinical Practice Guideline for the Treatment of Hemophilia

In a clinical practice guideline issued by the International Society on Thrombosis and Haemostasis and published online June 13 in the Journal of Thrombosis and Haemostasis, recommendations are presented for the treatment of congenital hemophilia.Suely M. Rezende, M.D., Ph.D., from the Universidade Federal de Minas Gerais in Belo Horizon

HealthDay 01 July at 03.22 PM

Amivantamab-Lazertinib Ups Survival in EGFR-Mutated Advanced Lung Cancer

For patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC), amivantamab-lazertinib yields improved progression-free survival compared with osimertinib as first-line treatment, according to a study published online June 26 in the New England Journal of Medicine.Byoung C. Cho, M.D., Ph.D., from the Yonsei Cancer Ce

HealthDay 01 July at 03.17 PM

Liberal Transfusion Strategy Not Beneficial for Patients With TBI, Anemia

A liberal transfusion strategy does not reduce the risk of unfavorable neurologic outcome at six months among critically ill patients with traumatic brain injury and anemia, according to a study published online June 13 in the New England Journal of Medicine to coincide with the annual Critical Care Reviews Meeting, held from June 12 to 14 in B

HealthDay 28 June at 10.09 PM

NCCN: Cancer Drug Shortages Remain a Challenge for Clinicians

Almost 90 percent of medical centers report cancer drug shortages, which often impact clinical trials, according to the results of a National Comprehensive Cancer Network survey.Following data published one year ago and six months ago illustrating shortages of crucial cancer drugs, the National Comprehensive Cancer Network published new results

HealthDay 28 June at 03.04 PM

Precision-Guided Treatment Improves Outcomes for High-Risk Pediatric Cancer

Precision-guided treatment improves outcomes for children with high-risk cancer, according to a study published online June 6 in Nature Medicine.Loretta M.S. Lau, M.B.B.S., Ph.D., from the Children's Cancer Institute at the University of New South Wales Sydney, and colleagues reported data from 384 patients with high-risk pediatric canc

HealthDay 28 June at 03.02 PM

Survival Improves With Open Hysterectomy for Cervical Cancer

For patients with early-stage cervical cancer, disease-free and overall survival are lower for patients undergoing minimally invasive versus open radical hysterectomy, according to a study published online June 25 in the Journal of Clinical Oncology.Pedro T. Ramirez, M.D., from the Methodist Hospital in Houston, and colleagues compared

HealthDay 28 June at 03.01 PM

Guidelines Address RT for Management of HPV-Linked Oropharyngeal Cancer

In a clinical practice guideline issued by the American Society for Radiation Oncology and published online June 18 in Practical Radiation Oncology, recommendations are presented for the use of radiation therapy (RT) for management of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC).Danielle N. Margali

HealthDay 27 June at 03.19 PM

Immunoglobulin Replacement Therapy Beneficial for Blood Cancers

Immunoglobulin replacement therapy (IgRT) is associated with reductions in hypogammaglobulinemia, infections, severe infections, and associated antimicrobial use among real-world patients with chronic lymphocytic leukemia (CLL) or non-Hodgkin lymphoma (NHL), according to a study published online June 21 in Blood Advances.Jacob D. Soum

HealthDay 27 June at 03.13 PM

PIK3CA Could Guide Use of COX-2 Inhibitors in Treatment for Colon Cancer

PIK3CA mutational status may be beneficial for predicting response to addition of the cyclooxygenase 2 (COX-2) inhibitor celecoxib to standard adjuvant chemotherapy in stage III resected colon cancer, according to a study published online June 18 in the Journal of Clinical Oncology.Jonathan A. Nowak, M.D., Ph.D., from Brigham

HealthDay 26 June at 06.03 PM

Glofitamab + GemOx Superior to Rituximab + GemOx for Lymphoma

Glofitamab (Glofit) plus gemcitabine and oxaliplatin (GemOx) is superior to rituximab (R)-GemOx for relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL), according to a study presented at the annual hybrid congress of the European Hematology Association, held from June 13 to 16 in Madrid.Jeremy Abramson, M.D., from the Massachusett

HealthDay 24 June at 03.15 PM

Acupuncture Reduces Endocrine Symptoms, Hot Flashes in Breast Cancer

A 10-week acupuncture intervention significant reduces endocrine symptoms and hot flashes among women with breast cancer receiving endocrine therapy (ET), according to a study published online June 24 in Cancer.Weidong Lu, M.P.H., Ph.D., from the Dana Farber Cancer Institute in Boston, and colleagues enrolled 158 patients with stage 0 t

HealthDay 24 June at 03.02 PM

Nonsignificant Survival Benefit Seen for Dabrafenib, Trametinib in Melanoma

For patients with resected stage III melanoma, adjuvant therapy with dabrafenib plus trametinib is associated with a nonsignificant benefit in terms of overall survival, according to a study published online June 19 in the New England Journal of Medicine.Georgina V. Long, M.D., Ph.D., from the University of Sydney, and colleagues random

HealthDay 24 June at 02.59 PM

Posttransplant Cyclophosphamide GVHD Prophylaxis Beneficial in Leukemia

For patients with acute myeloid leukemia (AML) undergoing allogeneic stem cell transplantation, posttransplant cyclophosphamide (PTCy) graft-versus-host-disease (GVHD) prophylaxis yields comparable relapse incidence (RI) and significantly lower incidence of GVHD than conventional prophylaxis, according to a study published online June 10 in the Ame

HealthDay 21 June at 10.54 PM

FDA Approves KEYTRUDA + Chemo for Primary Advanced, Recurrent Endometrial Carcinoma

The U.S. Food and Drug Administration has approved Keytruda (pembrolizumab) plus chemotherapy as treatment for adult patients with primary advanced or recurrent endometrial carcinoma. This is the third FDA-approved indication for Keytruda in endometrial carcinoma.The approval is for Keytruda, an anti-programmed death receptor-1&nbsp;(anti-PD-1)

HealthDay 21 June at 03.38 PM

Overall Prevalence of Being Up-to-Date With Lung Cancer Screening Is Low

The overall prevalence of up-to-date (UTD) lung cancer screening (LCS) was low in 2022, with prevalence increasing with age and number of comorbidities, according to a study published online June 10 in JAMA Internal Medicine.Priti Bandi, Ph.D., from the American Cancer Society in Atlanta, and colleagues estimated the contemporary preval

HealthDay 21 June at 03.31 PM

Surveillance IDs New Tumors in Children With Cancer Predisposition

Standardized surveillance identifies new tumors among children with a wide spectrum of cancer predisposition syndromes (CPSs), according to a study published online June 20 in JAMA Oncology.Alise Blake, from St. Jude Children's Research Hospital in Memphis, Tennessee, and colleagues reviewed surveillance outcomes for children and young

HealthDay 21 June at 03.29 PM

Study Quantifies Risk for Gastric, Breast Cancer for Germline CDH1 P/LP Variants

The cumulative risk for advanced gastric cancer varies from 6.5 to 10.3 percent for carriers of germline CDH1 pathogenic/likely pathogenic (P/LP) variants, according to a study published online June 14 in the Journal of the American Medical Association to coincide with presentation at the International Gastric Cancer Linkage Consortiu

HealthDay 21 June at 03.23 PM

Improved Outcomes Seen With Ibrutinib in Chronic Lymphocytic Leukemia

First-line ibrutinib is associated with better outcomes than chemoimmunotherapy among patients with chronic lymphocytic leukemia (CLL), according to a study published online May 13 in Clinical Lymphoma, Myeloma &amp; Leukemia.Nilanjan Ghosh, M.D., Ph.D., from the Levine Cancer Institute in Charlotte, North Carolina, and colleagues condu

HealthDay 20 June at 08.47 PM

FDA Approves Augtyro for NTRK-Positive Advanced Solid Tumors

The U.S. Food and Drug Administration has approved Augtyro (repotrectinib), a next-generation tyrosine kinase inhibitor (TKI), for the treatment of patients with neurotrophic tyrosine receptor kinase (NTRK)-positive locally advanced or metastatic solid tumors.Augtyro is approved for adult and pediatric patients (aged 12 years and olde

HealthDay 20 June at 04.00 PM

ViPOR Results in Durable Remission in Specific Subtypes of Lymphoma

For patients with specific subtypes of relapsed or refractory diffuse large B-cell lymphoma (DLBCL), treatment with venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide (ViPOR) yields durable remission, according to a study published in the June 20 issue of the New England Journal of Medicine.Christopher Melani, M.D., fro

HealthDay 20 June at 03.57 PM

Burden of Chronic Health Conditions Increased for LGTBQ+ Cancer Survivors

Cancer survivors who identify as lesbian, gay, bisexual, transgender, queer, plus (LGBTQ+) have an increased burden of all chronic health conditions, disabilities, and limitations, according to a study published online June 20 in Cancer Epidemiology, Biomarkers &amp; Prevention.Austin R. Waters, from the University of North Carolina a

HealthDay 20 June at 03.36 PM

Black Patients More Likely to Experience MACE After ADT for Prostate Cancer

Black patients are more likely to experience adverse cardiovascular outcomes after systemic androgen deprivation therapy (ADT) for prostate cancer, according to a study published online June 18 in JACC: CardioOncology.Biniyam G. Demissei, M.D., from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and

HealthDay 19 June at 09.29 PM

Dementia With Lewy Bodies Risk Down With α-1 Adrenergic Receptor Antagonists

Men taking α-1 adrenergic receptor antagonists terazosin, doxazosin, and alfuzosin (Tz/Dz/Az) seem to have a lower risk for dementia with Lewy bodies (DLB), according to a study published online June 19 in Neurology.Alexander Hart, M.D., M.P.H., from the University of Michigan in Ann Arbor, and colleagues used a new-user active compa

HealthDay 19 June at 03.55 PM

Low-Dose Direct Oral Anticoagulants Tied to More Bleeding Episodes

Patients with atrial fibrillation (AF) on low doses of direct oral anticoagulants (DOACs) have more bleeding episodes than those on standard doses, according to a study published online June 6 in&nbsp;Blood Advances.Gualtiero Palareti, M.D., from Fondazione Arianna Anticoagulazione in Bologna, Italy, and colleagues collected venous b

HealthDay 19 June at 11.05 AM

Dollar Tree Left Recalled Applesauce Pouches on Store Shelves Too Long, FDA Says

After a recall was issued last year for lead-tainted applesauce pouches linked to illnesses in over 500 children, the discount retailer Dollar Tree failed to remove all products from store shelves for too long, federal officials said Tuesday.In a&nbsp;<a href="https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/

HealthDay 18 June at 09.11 PM

Approximately 7 Percent of U.S. Population Uninsured in 2023

In 2023, 7.6 percent of the U.S. civilian noninstitutionalized population was uninsured, according to early estimates from the National Health Interview Survey, 2023, released by the National Center for Health Statistics.Robin A. Cohen, Ph.D., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues used data from

HealthDay 18 June at 03.49 PM

Trametinib Safe, Effective for Juvenile Myelomonocytic Leukemia

For children with relapsed or refractory juvenile myelomonocytic leukemia (JMML), trametinib is safe and effective, according to a study published online June 12 in Cancer Discovery.Noting that patients with relapsed or refractory (advanced) JMML have poor outcomes, Elliot Stieglitz, M.D., from the University of California San Francisc

HealthDay 18 June at 09.50 AM

Pandemic-Era Tax Credits Made Healthcare More Affordable, But They're Set to Expire

In a success story for Americans seeking affordable healthcare coverage, tax credits put in place during the pandemic helped millions gain health insurance, a new report found.Trouble is, the credits are set to expire at the end of 2025, noted a research team from the nonprofit Robert Wood Johnson Foundation (RWJ).According to RWJ's <a h

HealthDay 17 June at 10.53 PM

1999 to 2020 Saw Diet Quality Improve Among U.S. Adults

From 1999 to 2020, diet quality improved among U.S. adults, according to a study published online June 18 in the Annals of Internal Medicine.Junxiu Liu, Ph.D., from the Icahn School of Medicine at Mount Sinai in New York City, and Dariush Mozaffarian, M.D., Dr.P.H., from Tufts University in Boston, examined trends in diet quality by rac

HealthDay 14 June at 08.52 PM

Past-Year Pap Testing Rates Were Lower in 2022 Than 2019

Past-year Papanicolaou testing rates were lower in 2022 than in 2019, overall, and lower rates were seen in rural versus urban women, according to a study published in online June 14 in JAMA Network Open.Tyrone F. Borders, Ph.D., and Amanda Thaxton Wiggins, Ph.D., from the University of Kentucky in Lexington, examined receipt of a Papan

HealthDay 14 June at 03.35 PM

Second Tumors Are Rare After Chimeric Antigen Receptor T-Cell Therapy

Second tumors are rarely seen after chimeric antigen receptor (CAR) T-cell therapy, according to a study published in the June 13 issue of the New England Journal of Medicine.Mark P. Hamilton, M.D., Ph.D., from Stanford University in California, and colleagues examined the occurrence of second tumors after CAR T-cell therapy since 2016.

HealthDay 14 June at 03.34 PM

Neighborhood Deprivation Only Tied to Breast Cancer Mortality for White Women

Factors aside from neighborhood deprivation are responsible for increased breast cancer mortality among Black women, according to a study published online June 12 in&nbsp;JAMA Network Open.Lauren E. Barber, Ph.D., from the Emory University Rollins School of Public Health in Atlanta, and colleagues investigated whether neighborhood depri

HealthDay 13 June at 10.58 PM

Health Care Spending Growth Projected to Outpace GDP to 2032

Health care spending growth is projected to outpace that of the gross domestic product (GDP) during the coming decade, according to a study published online June 12 in Health Affairs.Jacqueline A. Fiore, Ph.D., from the Centers for Medicare &amp; Medicaid Services in Baltimore, and colleagues projected growth in national health expend

HealthDay 13 June at 03.54 PM

Alternative Pembrolizumab Administration Yields Environmental Advantages

Alternative pembrolizumab administration strategies may have environmental advantages, such as less carbon dioxide emission, according to a study published in the June issue of The Lancet Oncology.Alex K. Bryant, M.D., from the Veterans Affairs Center for Clinical Management Research in Ann Arbor, Michigan, and colleagues conducted a

HealthDay 13 June at 03.49 PM

Positive Psychology Intervention Aids Allogeneic Stem Cell Transplant Survivors

A telephone-delivered positive psychology intervention (Positive Affect for the Transplantation of Hematopoietic stem cells intervention [PATH]) is beneficial for allogeneic hematopoietic stem cell transplantation (HSCT) survivors, according to a study published online June 11 in the Journal of the National Comprehensive Cancer Network.<

HealthDay 13 June at 11.17 AM

J&J Settles Talcum Powder Lawsuits From States for $700 Million

Johnson &amp; Johnson will pay $700 million to settle claims from 42 states and the District of Columbia that the company continued to market its talcum powder products even as evidence tied them to a heightened risk for cancer.J&amp;J did not admit to any wrongdoing in settling with the states, which were led by Florida, Texas and North Carol

HealthDay 12 June at 03.05 PM

Adverse Effects of Medical Treatment Increasing Worldwide

The burden of adverse effects of medical treatment (AEMT) is increasing, with the proportion of all cases accounted for by the increasing rates seen in older adults, according to a study published online June 11 in BMJ Quality &amp; Safety.Liangquan Lin, from the Chinese Academy of Medical Sciences &amp; Peking University Medical Col

HealthDay 12 June at 02.50 PM

Generation X Experiencing Larger Per-Capita Increases in Cancer Incidence

Generation X is experiencing larger per-capita increases in the incidence of cancers than Baby Boomers, according to a study published online June 10 in JAMA Network Open.Philip S. Rosenberg, Ph.D., and Adalberto Miranda-Filho, Ph.D., from the National Cancer Institute in Bethesda, Maryland, estimated invasive cancer incidence trends

HealthDay 12 June at 11.29 AM

Biden Administration Pushes for Rule Wiping Medical Debt From Credit Reports

In an effort to keep medical debt from destroying credit scores, the Biden administration announced Tuesday that it is moving ahead with a proposal that would remove health care bills from consideration in credit checks.Along with making it easier for people to rent an apartment, get a mortgage or buy a car, the proposed rule would prevent le

HealthDay 11 June at 03.48 PM

No Link Seen Between Exposure to Immunosuppressive Therapy, Cancer in IBD Patients

There is no significant association between exposure to immunosuppressive therapies and development of incident cancers among patients with inflammatory bowel disease (IBD) and a history of cancer, according to a study published online May 18 in Clinical Gastroenterology and Hepatology.Steven H. Itzkowitz, M.D., from the Icahn School o

HealthDay 11 June at 03.42 PM

ENDO: Early Menopause Tied to Heightened Risk for Breast, Ovarian Cancer

Women with early menopause have a two times greater risk for breast cancer and a nearly four times higher risk for ovarian cancer, according to a study presented at the annual meeting of the Endocrine Society, held from June 1 to 4 in Boston.Kristina&nbsp;L. Allen-Brady, Ph.D., M.P.H., from University of Utah in Salt Lake City, and colleagues i

HealthDay 11 June at 03.39 PM

AI Cuts Radiologists' Workload in Mammography Screening

Implementation of artificial intelligence (AI) into a population-based mammography screening program reduced the overall workload of radiologists while improving screening performance, according to a study published online June 4 in&nbsp;Radiology.Andreas D. Lauritzen, Ph.D., from University of Copenhagen in Denmark, and colleagues com

HealthDay 10 June at 04.24 PM

American Society of Clinical Oncology, May 30-June 4

The annual meeting of the American Society of Clinical Oncology was held from May 30 to June 4 in Chicago and hosted more than 34,000 participants from around the world, including clinicians, academicians, allied health professionals, and others interested in oncology. The conference featured the latest advances in clinical cancer research,

HealthDay 10 June at 03.36 PM

Planetary Health Diet Index Linked to Lower Total, Cause-Specific Mortality

A higher Planetary Health Diet Index (PHDI) is associated with a lower risk for total and cause-specific mortality, according to a study published online June 10 in the American Journal of Clinical Nutrition.Linh P. Bui, M.D., Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues developed a PHDI to quantif

HealthDay 10 June at 03.32 PM

Lung Cancer Screening Increases Earlier-Stage Diagnoses, Improves Survival

Lung cancer screening (LCS) is associated with earlier-stage diagnoses and improved survival, according to a study published online June 10 in Cancer.Donna M. Edwards, M.D., Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined the impact of LCS among patients in the Veterans Health Administration (VA) health care

HealthDay 10 June at 03.24 PM

Prevalence of Iron Deficiency Varies With Different Definitions

The prevalence of iron deficiency varies significantly with three different definitions, according to a study published online June 7 in JAMA Network Open.James C. Barton, M.D., from the University of Alabama at Birmingham, and colleagues compared the prevalence of iron deficiency among women using three different definitions based on d

HealthDay 10 June at 03.10 PM

New Clinical Score Can Predict Immune Checkpoint Blockade Response

For patients with cancer, a novel clinical score using a six-feature regression model can predict immune checkpoint blockade (ICB) response probability and patient survival, according to a study published online June 3 in Nature Cancer.Tian-Gen Chang, Ph.D., from the National Institutes of Health in Bethesda, Maryland, and colleagues an

HealthDay 10 June at 02.59 PM

AI Blood-Based Lung Cancer Screening Test Developed for Fragmentome

A novel blood-based lung cancer screening test has been developed and validated using genome-wide sequencing to analyze cell-free DNA (cfDNA) fragmentation profiles, according to a study published online June 3 in Cancer Discovery.Noting that changes in genome-wide cfDNA fragmentation profiles (fragmentomes) in peripheral blood reflect

HealthDay 07 June at 03.35 PM

Resistance Exercise Boosts Outcomes After Early-Stage Breast Cancer Surgery

Early resistance exercise following surgery for early-stage breast cancer improves shoulder range of motion (ROM) and strength at one month and six months postsurgery, according to a study published online June 5 in&nbsp;JAMA Surgery.Jihee Min, Ph.D., from the National Cancer Center in Goyang-si, South Korea, and colleagues investigated

HealthDay 07 June at 03.34 PM

ASCO: Germline Variation Does Not Predict Taxane-Induced Peripheral Neuropathy

Germline variation does not predict the risk of taxane-induced peripheral neuropathy (TIPN) in Black women receiving paclitaxel (once weekly) or docetaxel (every three weeks) for early-stage breast cancer, according to a study published online June 3 in the Journal of Clinical Oncology to coincide with the annual meeting of the American Society

HealthDay 07 June at 03.30 PM

Higher County-Level Prostate Cancer Screening Tied to Better Outcomes

Higher county-level prevalence of prostate-specific antigen (PSA) screening is associated with lower odds of advanced disease, all-cause mortality, and prostate cancer-specific mortality, according to a study published online June 4 in&nbsp;JAMA Network Open.Hari S. Iyer, Sc.D., from Rutgers Cancer Institute of New Jersey in New Brunswic

HealthDay 06 June at 10.22 PM

Heavy Cannabis Use Linked to CVD Mortality in Women

Heavy cannabis use is associated with a significantly increased risk for cardiovascular disease (CVD) mortality among women, according to a study published online June 6 in JAMA Network Open.Alexandre Vallée, M.D., Ph.D., from Foch Hospital in Suresnes, France, examined sex-stratified associations of cumulative lifetime cannabis use wi

HealthDay 06 June at 04.12 PM

ASCO: Ivonescimab Improves Progression-Free Survival in EGFR+ Lung Cancer

For patients with non-small cell lung cancer with the epidermal growth factor receptor (EGFR) variant, ivonescimab plus chemotherapy improves progression-free survival, according to a study published online May 31 in the Journal of the American Medical Association to coincide with the annual meeting of the American Society of Clinica

HealthDay 06 June at 03.55 PM

Smoking Cessation Aids Equally Effective in Those With Mental Health Conditions

Popular smoking cessation aids are equally effective in those with or without a history of mental health conditions, according to a study published online June 4 in&nbsp;PLOS Mental Health.Sarah E. Jackson, Ph.D., from University College London, and colleagues examined whether the real-world effectiveness of popular smoking cessation a

HealthDay 05 June at 09.18 PM

Neoadjuvant Nivolumab, Ipilimumab Safe for dMMR Colon Cancer

Neoadjuvant nivolumab plus ipilimumab has an acceptable safety profile in patients with locally advanced mismatch repair-deficient (dMMR) colon cancer, according to a study published in the June 6 issue of the New England Journal of Medicine.Myriam Chalabi, M.D., Ph.D., from the Netherlands Cancer Institute in Amsterdam, and colleague

HealthDay 05 June at 03.31 PM

ASCO: Osimertinib Improves Progression-Free Survival in EGFR-Mutated Lung Cancer

For patients with unresectable stage III EGFR-mutated non-small cell lung cancer (NSCLC), treatment with osimertinib results in significantly longer progression-free survival, according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the American Society of Clinical On

HealthDay 05 June at 03.28 PM

ASCO: Neoadjuvant Ipilimumab + Nivolumab Ups Survival in Resectable Melanoma

Neoadjuvant ipilimumab plus nivolumab followed by surgery results in longer event-free survival than surgery followed by adjuvant nivolumab among patients with resectable, macroscopic stage III melanoma, according to a study published online June 2 in the New England Journal of Medicine to coincide with the annual meeting of the American Soc

HealthDay 05 June at 03.26 PM

ASCO: Asciminib Has Superior Efficacy to TKIs for Newly Diagnosed Leukemia

For patients with newly diagnosed chronic myeloid leukemia (CML), asciminib shows superior efficacy and a favorable safety profile compared with investigator-selected tyrosine kinase inhibitors (TKIs), according to a study published online May 31 in the New England Journal of Medicine to coincide with the annual meeting of the American Socie

HealthDay 05 June at 03.16 PM

Lowering FIT Positivity Thresholds Improves Sensitivity, Specificity

Lowering the fecal immunochemical test (FIT) positive threshold yields levels of sensitivity and specificity that are comparable to those reported for multitarget stool RNA (mt-sRNA) testing without the additional testing, according to a research letter published online June 1 in the Journal of the American Medical Association.Tobias

HealthDay 04 June at 10.31 PM

ASCO: Stepped-Care Model Noninferior to Early Palliative Care for Advanced Cancer

For patients with advanced lung cancer, a stepped-care model with palliative care visits occurring at key points in patients' cancer trajectory is noninferior to early palliative care, according to a study published online June 2 in the Journal of the American Medical Association to coincide with the annual meeting of the American Society of C

HealthDay 04 June at 10.28 PM

Excess Mortality Persisted in Western World From 2020 Through 2022

Excess mortality persisted in 2020 through 2022 in the Western world, according to a study published online June 3 in BMJ Public Health.Saskia Mostert, M.D., from Amsterdam UMC, and colleagues explored excess mortality in the Western world from 2020 to 2022 using all-cause mortality reports abstracted from the "Our World in Data" databa

HealthDay 04 June at 03.55 PM

Gastrectomy for Gastric Cancer Tied to Lower Risk for Cardiovascular Events

Patients with gastric cancer who undergo gastrectomy have a lower risk for cardiovascular events than the general population, according to a study published online March 28 in the&nbsp;International Journal of Surgery.Yeongkeun Kwon, M.D., Ph.D.,&nbsp;from the Korea University College of Medicine in Seoul, and colleagues used data from

HealthDay 03 June at 09.12 PM

9.6 Percent of Medical Visits Took Place Via Telehealth in 2021

In 2021, 9.6 percent of medical visits took place via telehealth, with a higher percentage seen for mental health visits, according to a research letter published online June 4 in the Annals of Internal Medicine.Sandra L. Decker, Ph.D., from the Agency for Healthcare Research and Quality in Rockville, Maryland, and colleagues describe te

HealthDay 03 June at 09.05 PM

First-Line Biparametric MRI Less Cost-Effective Than PSA for Prostate Cancer Screening

From an economic perspective, first-line prostate-specific antigen (PSA) testing is favored over biparametric magnetic resonance imaging (bpMRI) for prostate cancer screening, mainly due to false-positive results and overdiagnosis, according to a study published online June 4 in the Annals of Internal Medicine.Roman Gulati, from the Fred

HealthDay 31 May at 08.45 PM

Active Surveillance Effective Strategy for Favorable-Risk Prostate Cancer

Active surveillance is an effective management strategy for men with favorable-risk prostate cancer, with an estimated rate of metastasis of 1.4 percent at 10 years after diagnosis, according to a study published online May 30 in the Journal of the American Medical Association.Lisa F. Newcomb, Ph.D., from the Fred Hutchinson Cancer Cente

HealthDay 31 May at 04.00 PM

Longer Transfer Gap to Adult Care Increases Inpatient Encounters in Sickle Cell Disease

For young adults (YAs) with sickle cell disease (SCD), a longer transfer gap is associated with increased inpatient encounters and decreased outpatient encounters in adult health care, according to a study published online May 29 in Blood Advances.Kristen E. Howell, Ph.D., M.P.H., from Texas A&amp;M University in College Station, and col

HealthDay 31 May at 03.54 PM

Maternal Serum Alpha-Fetoprotein Levels Higher in Black Than White Women

Maternal serum alpha-fetoprotein (AFP) levels are higher in Black than White pregnant women, supporting the use of accounting for these differences in prenatal open neural tube defect (ONTD) screening, according to a study published online May 23 in Clinical Chemistry.Geralyn Messerlian, Ph.D., from the Women &amp; Infants Hospital and t

HealthDay 30 May at 10.23 PM

Pandemic Had Temporary Negative Effect on Breast Cancer Screening

The COVID-19 pandemic had a transient negative effect on breast cancer screening overall and a prolonged negative effect on follow-up screening, according to a study published in the May/June issue of the Annals of Family Medicine.Andrew Chung, from Pennsylvania State University in University Park, and colleagues evaluated the pandemic

HealthDay 30 May at 04.01 PM

Patient Characteristics Linked to Performance of AI Algorithm for DBT

For analyzing negative screening digital breast tomosynthesis (DBT) examinations, patient characteristics influence the case and risk scores of an artificial intelligence (AI) algorithm, according to a study published online May 21 in Radiology.Derek L. Nguyen, M.D., from the Duke University School of Medicine in Durham, North Carolina

HealthDay 30 May at 03.58 PM

At-School Vaccination Boosts HPV Vaccination Coverage

At-school vaccination may be a useful tool to increase human papillomavirus (HPV) vaccination coverage among adolescents, according to a study published online May 23 in JAMA Network Open.Nathalie Thilly, Ph.D., from Université de Lorraine in Nancy, France, and colleagues examined the effectiveness of a three-component intervention (ed

HealthDay 30 May at 03.39 PM

Recommendations Issued for Palliative RT for Symptomatic Bone Mets

In a clinical practice guideline issued by the American Society for Radiation Oncology and published online May 22 in Practical Radiation Oncology, evidence-based recommendations are presented for the use of palliative external beam radiation therapy (RT) for symptomatic bone metastases.Sarah Alcorn, M.D., Ph.D., M.P.H., from the Unive

HealthDay 29 May at 09.17 PM

2007 to 2019 Saw Increase in Inflation-Adjusted Health Care Spending

From 2007 to 2019, there was an increase in inflation-adjusted health care spending, largely due to increasing contributions to premiums, according to a research letter published online May 28 in JAMA Internal Medicine.Sukruth A. Shashikumar, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cro

HealthDay 29 May at 03.20 PM

Tattoos May Increase Risk of Malignant Lymphoma

Tattoo exposure is associated with an increased risk of several malignant lymphoma subtypes, according to a study published online in the June issue of&nbsp;eClinicalMedicine.Christel Nielsen, Ph.D., from Lund University in Sweden, and colleagues used Swedish National Authority Registers to investigate the association between tattoo e

HealthDay 29 May at 03.16 PM

Diagnosis of Early-Onset Colorectal Cancer Often Delayed

Nearly half of individuals diagnosed with early-onset colorectal cancer (EOCRC) present with hematochezia and abdominal pain and one-quarter present with altered bowel habits, according to a review published online May 24 in&nbsp;JAMA Network Open.Joshua Demb, Ph.D., from the University of California, San Diego, and colleagues examine

HealthDay 29 May at 03.05 PM

Chemo + Breast Cancer Combo Accelerates Functional Decline in Seniors

The combination of breast cancer and chemotherapy contributes to accelerated functional decline in older women with early-stage breast cancer, according to a study published online April 28 in the&nbsp;Journal of Cancer Survivorship.Mina S. Sedrak, M.D., from the University of California Los Angeles David Geffen School of Medicine, an

HealthDay 28 May at 10.04 PM

Living Outside of Comprehensive Cancer Center Catchment Area Tied to Later-Stage Diagnosis

Disadvantaged populations and those living outside of a comprehensive cancer center's main catchment area have higher odds of receiving a diagnosis of late-stage cancer, according to a study published online May 2 in&nbsp;JAMA Network Open.Michael R. Desjardins, Ph.D., from Johns Hopkins University in Baltimore, and colleagues used spat

HealthDay 28 May at 03.19 PM

Considerable Variation Seen in Mortality Rates for Suspected Sepsis

There is considerable variation in mortality rates among patients with suspected sepsis, according to a research letter published online May 28 in the Annals of Internal Medicine.Brett Biebelberg, from Massachusetts General Hospital in Boston, and colleagues conducted a retrospective analysis of all adults admitted to five Massachusetts

HealthDay 28 May at 03.11 PM

Omission of SLNB Feasible for Younger Patients With ER+/cN0 Breast Cancer

A novel natural language understanding (NLU) pipeline can identify the rates of lymphedema and node positivity among women with estrogen receptor-positive (ER+), clinically node-negative (cN0) breast cancer, according to a study published online May 22 in JCO Clinical Cancer Informatics.Neil Carleton, from the UPMC Hillman Cancer Center

HealthDay 28 May at 03.00 PM

Disparities Seen in Cancer Treatment Delivery at Minority-Serving Hospitals

There are systemic disparities in definitive cancer treatment delivery at minority-serving hospitals (MSHs) versus non-MSHs, according to a study published online May 27 in Cancer.Edoardo Beatrici, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from the National Cancer Database for 2010 to 2019 to examine pa

HealthDay 28 May at 02.56 PM

ASCO: Conjugated Equine Estrogen May Increase Risk for Ovarian Cancer

Conjugated equine estrogen (CEE) taken alone for menopause may increase the risk for developing and dying from ovarian cancer, according to a study presented at the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago.Rowan T. Chlebowski, M.D., Ph.D., from the Lundquist Institute in Torrance, Califor

HealthDay 24 May at 10.13 PM

Primary HPV Screening Intervals Could Be Extended

Primary human papillomavirus (HPV) screening intervals could be extended, with the risk for cervical precancer or worse (CIN2+) eight years after negative HPV screening comparable to risk after three years in cytology cohorts, according to a study published online May 22 in Cancer Epidemiology, Biomarkers &amp; Prevention.Anna Gottschlic

HealthDay 24 May at 04.01 PM

Donepezil Not Beneficial for Cognitive Impairment in Breast Cancer Survivors

A once-daily dose of donepezil does not improve cognitive function among breast cancer survivors exposed to chemotherapy one to five years earlier, according to a study published online May 6 in the Journal of Clinical Oncology.Stephen R. Rapp, Ph.D., from the Wake Forest University School of Medicine in Winston-Salem, North Carolina, an

HealthDay 24 May at 03.56 PM

Risk for Periprosthetic Joint Infections Increased With Chemo After Arthroplasty

Postoperative chemotherapy is associated with an increased incidence of periprosthetic joint infections (PJI) among patients with total joint arthroplasties, according to a study published online May 2 in the Archives of Orthopaedic and Trauma Surgery.Amir Human Hoveidaei, M.D., from the Rubin Institute for Advanced Orthopedics at the Si

HealthDay 24 May at 03.50 PM

New Tool IDs Sexual Struggles in Female Partners of Prostate Cancer Patients

The Sexual Concerns In Partners of Patients with Prostate cancer tool is a valid measure of sexual health in female partners of patients with prostate cancer, according to a study published online May 17 in European Urology Oncology.Stacy Loeb, M.D., from NYU Langone Health in New York City, and colleagues described the development and v

HealthDay 24 May at 12.19 PM

FDA Panel Gives Nod to Blood Test for Colon Cancer

A U.S. Food and Drug Administration advisory panel on Thursday recommended the approval of a new blood test that can spot colon cancer.The panel voted 7-2 that the benefits outweigh the risks when using the Guardant Health's Shield test for&nbsp;colon cancer</a

HealthDay 23 May at 09.21 PM

ASCO: Survivors of Early Breast Cancer Can Successfully Attempt Pregnancy

Most survivors of stage 0 to III breast cancer who attempt pregnancy postdiagnosis are able to become pregnant and have a live birth, according to a study presented at the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago.Kimia Sorouri, M.D., M.P.H., from the Dana-Farber Cancer Institute in Bosto

HealthDay 23 May at 09.18 PM

ASCO: HPV Vaccination Positively Affecting More Than Just Cervical Cancer Risk

Human papillomavirus (HPV) vaccination is associated with reduced odds of several types of HPV-related cancers, not just cervical cancer, according to a study presented at the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago.Jefferson DeKloe, from Thomas Jefferson University in Philadelphia, and

HealthDay 23 May at 04.03 PM

2024 ASCO Annual Meeting: Patient Care Takes Center Stage

THURSDAY, May 23, 2024 (HealthDay News) --&nbsp;The 2024 American Society of Clinical Oncology (ASCO) Annual Meeting is being held May 31 to June 4, 2024, in Chicago and online.The theme of this year's meeting is The Art and Science of Cancer Care: From Comfort to Cure. Attendees will share and discuss the latest clinical cancer research impacting patient care. "Treatment advan

HealthDay 23 May at 04.03 PM

2024 ASCO Annual Meeting to Focus on Clinical Cancer Research Impacting Patient Care

THURSDAY, May 23, 2024 (HealthDay News) --&nbsp;The 2024 American Society of Clinical Oncology (ASCO) Annual Meeting is being held May 31 to June 4, 2024, in Chicago and online.The theme of this year's meeting is The Art and Science of Cancer Care: From Comfort to Cure. Attendees will share and discuss the latest clinical cancer research impacting patient care. "Treatment advan

HealthDay 23 May at 03.55 PM

Metformin Use Linked to Lower Odds of Myeloproliferative Neoplasms

Metformin use, including long-term use, is associated with significantly lower odds of myeloproliferative neoplasm (MPN) diagnosis, according to a study published online May 17 in Blood Advances.Daniel Tuyet Kristensen, M.D., from Aalborg University Hospital in Denmark, and colleagues conducted a population-based case-control study usi

HealthDay 23 May at 03.46 PM

4-Dimensional Model Can Predict Lymph Node Metastases in Breast Cancer

A deep learning model using tumor dynamic contrast-enhanced breast magnetic resonance imaging (MRI) has high sensitivity for identifying lymph node metastasis, according to a study published online April 12 in Radiology: Imaging Cancer.Dogan S. Polat, M.D., from the University of Texas Southwestern Medical Center in Dallas, and colleag

HealthDay 22 May at 03.53 PM

Metastatic Cancer Survival No Better at Practices With Higher NQF 0210 Rates

For patients with metastatic or advanced cancer, treatment at practices with higher rates of National Quality Forum (NQF) 0210 (patients receiving chemotherapy in the last 14 days of life) is not associated with improved survival, according to a study published online May 16 in JAMA Oncology.Maureen E. Canavan, Ph.D., from the Yale Sc

HealthDay 22 May at 03.50 PM

Global Life Expectancy, Disease Burden Set to Keep Improving

Life expectancy and age-standardized disease burden are expected to continue improving between 2022 and 2050, according to the Global Burden of Disease (GBD) study, published in the May 18 issue of The Lancet.Stein Emil Vollset, M.D., M.P.H., and colleagues from the GBD 2021 Forecasting Collaborators provide a reference forecast and a

HealthDay 22 May at 03.48 PM

E-Cigarette Use After Smoking May Up Risk for Lung Cancer

Former cigarette smokers who use electronic cigarettes may have a higher risk for lung cancer than those who do not vape, according to a study presented at the American Thoracic Society 2024 International Conference, held from May 17 to 22 in San Diego.Yeon Wook Kim, M.D., from the Seoul National University Bundang Hospital in South Korea, and

HealthDay 21 May at 11.04 PM

Offering Choice of CRC Screening Increases Completion Rates

For adults who are not up to date with colorectal cancer screening, offering a choice of colonoscopy or fecal immunochemical testing (FIT) increases screening completion rates, according to a study published online April 30 in Clinical Gastroenterology and Hepatology.Shivan J. Mehta, M.D., from the Perelman School of Medicine at the Uni

HealthDay 21 May at 03.05 PM

Survival Benefit for Cancer Trial Participants Does Not Persist in Adjusted Analyses

In studies using designs addressing sources of bias and confounding, there is no evidence of a survival benefit for cancer trial participants, according to a study published online May 20 in the Journal of the American Medical Association to coincide with the annual meeting of the Society for Clinical Trials, held from May 19 to 22 in Boston.<

HealthDay 21 May at 02.52 PM

Genital Talc Use Positively Linked to Ovarian Cancer

There is a positive association between use of intimate care products, including genital talc, and ovarian cancer, according to a study published online May 15 in the Journal of Clinical Oncology.Katie M. O'Brien, Ph.D., from the National Institutes of Health in Research Triangle Park, North Carolina, and colleagues examined the associa

HealthDay 20 May at 10.34 PM

No Association Found for Autoimmune Disease, Monoclonal Gammopathy

In a systematically screened population, there is no association between autoimmune disease and monoclonal gammopathy of undetermined significance (MGUS), according to a study published online May 21 in the Annals of Internal Medicine.Ingigerdur Sverrisdottir, M.D., from the University of Iceland in Reykjavik, and colleagues conducted a

HealthDay 20 May at 03.58 PM

Individuals With BAP1 Have High Rate of Nail Abnormalities

Individuals with BRCA1-associated protein (BAP1) have a high rate of nail abnormalities consistent with onychopapillomas, according to a study published online May 17 in JAMA Dermatology to coincide the annual meeting of the Society for Investigative Dermatology, held from May 15 to 18 in Dallas.Alexandra Lebensohn, from the Nat

HealthDay 17 May at 04.30 PM

Andexanet Yields Better Control of Hematoma Expansion Than Usual Care

For patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage, andexanet alfa, which reverses the effects of factor Xa inhibitors, results in better control of hematoma expansion than usual care, according to a study published in the May 16/23 issue of the New England Journal of Medicine.

HealthDay 17 May at 04.22 PM

AI Chatbots Can Generate Quality, Empathetic, Readable Responses

For patient questions about cancer, artificial intelligence (AI) chatbots can generate quality, empathetic, and readable responses, according to a study published online May 16 in JAMA Oncology.David Chen, from the Princess Margaret Hospital Cancer Centre in Toronto, and colleagues examined the competency of AI chatbots (GPT-3.5 [chatbot

HealthDay 17 May at 04.18 PM

Perioperative Nivolumab Tops Chemo for Survival in Resectable Lung Cancer

For patients with resectable non-small cell lung cancer (NSCLC), perioperative treatment with nivolumab results in significantly longer event-free survival, according to a study published in the May 16/23 issue of the New England Journal of Medicine.Tina Cascone, M.D., Ph.D., from the University of Texas MD Anderson Cancer Center in Hous

HealthDay 17 May at 12.03 PM

FDA Approves New Drug for Deadly Lung Cancer

The U.S. Food and Drug Administration on Thursday approved a new drug to treat patients with an advanced form of deadly lung cancer. Importantly, tarlatamab (Imdelltra) is only for pa

HealthDay 16 May at 03.57 PM

Quality Improvement Initiative Boosts Early HPV Vaccine Rates

A multipronged primary care quality improvement initiative increases early human papillomavirus (HPV) vaccine initiation across racial/ethnic, sociodemographic, insurance, and geographic groups, according to a study presented at the annual meeting of the Pediatric Academic Societies, held from May 2 to 6 in Toronto.Caitlin Miller, from Nemours

HealthDay 16 May at 03.32 PM

Oldest Adults With Acute Myeloid Leukemia Benefit From Venetoclax

For older adults with acute myeloid leukemia (AML), venetoclax (VEN) combined with a hypomethylating agent (HMA) is safe and effective and can prolong survival, according to a study published online May 7 in Blood Neoplasia.Ellen Madarang, Pharm.D., from the University of Miami Sylvester Comprehensive Cancer Center, and colleagues cond

HealthDay 16 May at 03.25 PM

For Women With Obesity, Risk for Breast Cancer Drops After Bariatric Surgery

For women with obesity, the risk for breast cancer is reduced after bariatric surgery, according to a study published online May 15 in JAMA Surgery.Felipe M. Kristensson, M.D., from the Sahlgrenska Academy at the University of Gothenburg in Sweden, and colleagues examined whether bariatric surgery is associated with breast cancer incid

HealthDay 15 May at 09.01 PM

Plant-Based Diets Tied to Long-Term Health Benefits

Plant-based diets appear beneficial in lowering cardiometabolic risk factors, as well as cardiovascular diseases (CVDs), cancer risk, and mortality, according to a review published online May 15 in&nbsp;PLOS ONE.Angelo Capodici, M.D., from Alma Mater Studiorum-University of Bologna in Italy, and colleagues conducted an umbrella review

HealthDay 15 May at 07.29 PM

Non-Hispanic Black Melanoma Patients Present With Advanced Disease

Non-Hispanic Black (NHB) melanoma patients have distinct tumor characteristics, presenting with more advanced disease and exhibiting worse outcomes, according to a study published in the May issue of the Journal of Surgical Oncology.Jessica A. Steadman, M.B.B.S., from the Mayo Clinic in Rochester, Minnesota, and colleagues examined fe

HealthDay 15 May at 03.45 PM

AACR Delivers Report on Disparities in Cancer Progress

In its biennial Cancer Disparities Progress Report published today, the American Association for Cancer Research presents the latest statistics on disparities in cancer progress experienced by ethnic-minority groups and other medically underserved populations in the United States.Robert A. Winn, M.D., from the Virginia Commonwealth Un

HealthDay 15 May at 02.34 PM

FDA Approves First Self-Test Collection Kit for HPV

The U.S. Food and Drug Administration has approved a kit that will allow women to collect their own vaginal sample for HPV screening, a move that could increase early detection in those at risk for cervical cancer.Women will be able to swab thems

HealthDay 14 May at 03.47 PM

Disparities Seen in Carbapenem-Resistant Enterobacterales Bloodstream Infection Outcomes

Black female patients hospitalized for carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSI) face increased 30-day mortality, according to a study presented at the annual European Society of Clinical Microbiology and Infectious Diseases Global Congress, held from April 27 to 30 in Barcelona, Spain.Felicia Ruffin, Ph.D., from t

HealthDay 14 May at 12.13 PM

San Francisco Set to Ban 'Forever Chemicals' in Firefighter Gear

San Francisco is on the verge of passing a ban on "forever chemicals" in the protective clothing firefighters wear while battling blazes.City lawmakers are expected to pass an ordinance on Tuesday&nbsp

HealthDay 13 May at 10.46 PM

DDW: 1999 to 2020 Saw Rise in Incidence of Colorectal Cancer in People Under 45

For individuals aged younger than 45 years, the incidence of colorectal cancer increased considerably from 1999 to 2020, with a 333 percent increase among those aged 15 to 19 years, according to a study presented at the 2024 Digestive Disease Week, held from May 18 to 21 in Washington, D.C.Islam Mohamed, M.D., from the University of Missouri-Kans

HealthDay 13 May at 10.34 PM

Physicians With Disabilities May Experience Depersonalization

Physicians with disabilities (PWDs) are significantly more likely to experience depersonalization but not emotional exhaustion when compared with their peers without disabilities, according to a research letter published online May 9 in&nbsp;JAMA Network Open.Lisa M. Meeks, Ph.D., from the University of Michigan Medical School in Ann Arb

HealthDay 13 May at 03.53 PM

Metabolic Syndrome, Obesity Independently Linked to Breast Cancer

Metabolic syndrome (MetS) and obesity have independent and distinct associations with breast cancer subtypes and mortality, according to a study published online May 13 in Cancer.Rowan T. Chlebowski, M.D., Ph.D., from The Lundquist Institute in Torrance, California, and colleagues examined the associations of MetS and obesity with postme

HealthDay 10 May at 09.58 PM

Lower Prevalence of Employment Seen for Survivors of Childhood Cancer

Adult survivors of childhood cancer have declines in employment and increases in health-related unemployment compared with the general population, according to a study published online May 10 in JAMA Network Open.Neel S. Bhatt, M.B.B.S., M.P.H., from the Fred Hutchinson Cancer Center in Seattle, and colleagues conducted a retrospective c

HealthDay 10 May at 04.07 PM

Large Language Models Fall Short in Breast Imaging Classification

Large language models (LLMs) appear to fall short in classification of breast imaging, which can have a negative impact on clinical management, according to a study published online April 30 in Radiology.Andrea Cozzi, M.D., Ph.D., from the Ente Ospedaliero Cantonale in Lugano, Switzerland, and colleagues examined the agreement between hu

HealthDay 10 May at 12.42 PM

Cyberattack Cripples Major U.S. Health Care Network

Ascension, a major U.S. health care system with 140 hospitals in 19 states, announced late Thursday that a cyberattack has caused disruptions at some of its hospitals."Systems that are currently unavailable include our electronic health records system, MyChart (which enables patients to view their medical records and communicate with their provid

HealthDay 09 May at 09.03 PM

Those With Limited English Proficiency Face Barriers to Telehealth

For individuals with limited English proficiency, there are disparities in telehealth access, as well as worse video visit experiences, according to a research letter published May 9 in&nbsp;JAMA Network Open.Jorge A. Rodriguez, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from 24,453 adult participants in

HealthDay 09 May at 08.54 PM

Racial, Ethnic Differences Seen in Breast Cancer Treatment Declination

For patients with breast cancer, there are racial and ethnic differences in treatment declination, according to a study published online May 9 in JAMA Network Open.Jincong Q. Freeman, M.P.H., from the University of Chicago, and colleagues examined trends and racial and ethnic disparities in treatment declination and overall survival usi

HealthDay 09 May at 04.01 PM

Symptom Burden Prevalent in Childhood Cancer Survivors

Symptom burden is prevalent among young childhood cancer survivors, with caregiver anxiety and greater neighborhood deprivation associated with greater symptom burden, according to a study published online May 7 in JAMA Network Open.Madeline R. Horan, Ph.D., from the St. Jude Children's Research Hospital in Memphis, Tennessee, and colle

HealthDay 09 May at 03.58 PM

Bariatric Surgery Tied to Higher Short-Term Risk for Venous Thromboembolism

In the short term, bariatric surgery is associated with a greater risk for venous thromboembolism (VTE), but in the long-term, it is associated with lower risk, according to a study published online April 30 in&nbsp;Obesity Surgery.Laura B. Harrington, Ph.D., M.P.H., from Kaiser Permanente Washington Health Research Institute in Seattle

HealthDay 09 May at 03.53 PM

Mortality Slightly Increased With Consumption of Ultraprocessed Foods

Mortality is slightly higher in association with a higher intake of ultraprocessed foods, according to a study published online May 8 in The BMJ.Zhe Fang, M.B.B.S., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues conducted a population-based cohort study to examine the association of ultraprocessed food cons

HealthDay 08 May at 02.52 PM

NECTIN4 Amplifications Predict Outcomes in Metastatic Urothelial Cancer

For patients with metastatic urothelial cancer (mUC), NECTIN4 amplifications predict anti-NECTIN4 antibody-drug conjugate enfortumab vedotin (EV) response and outcomes, according to a study published online April 24 in the Journal of Clinical Oncology.Niklas Klumper, M.D., from University Hospital Bonn in Germany, and colleagu

HealthDay 08 May at 02.31 PM

Persistent Sociodemographic Differences Seen in Use of AutoHCT for Multiple Myeloma

Sociodemographic differences persist in utilization of autologous hematopoietic cell transplantation (autoHCT) for multiple myeloma, according to a study published in the April issue of Clinical Lymphoma, Myeloma &amp; Leukemia.Naseem S. Esteghamat, M.,D., from the University of California Davis Comprehensive Cancer Center in Sacrament

HealthDay 07 May at 10.44 PM

Most Socially Vulnerable Counties Less Likely to Have Cancer Trials

The most socially vulnerable counties are less likely to have any cancer clinical trial, according to a research letter published online May 7 in JAMA Network Open.Rishi Robert Sekar, M.D., from the University of Michigan in Ann Arbor, and colleagues examined the association between county-level social determinants of health (SDOH) and c

HealthDay 07 May at 03.10 PM

Risk for Colorectal Cancer Is Low for Uncomplicated Diverticulitis

The prevalence of colorectal cancer (CRC) is low for patients undergoing colonoscopy after an episode of uncomplicated diverticulitis, according to a study published online April 24 in Clinical Gastroenterology and Hepatology.Walker D. Redd, M.D., from the University of North Carolina in Chapel Hill, and colleagues used data from the Gas

HealthDay 06 May at 10.14 PM

Mortality Risk Up for Cancer Survivors With Elevated Loneliness

Cancer survivors with elevated loneliness have a higher mortality risk, according to a study published online April 25 in the Journal of the National Comprehensive Cancer Network.Jingxuan Zhao, M.P.H., from the American Cancer Society in Atlanta, and colleagues identified a longitudinal cohort of cancer survivors aged 50 years and older f

HealthDay 06 May at 04.18 PM

Text Message Outreach Can Help Increase Mammogram Completion Rates

Text messaging women after initial outreach for breast cancer screening increases mammogram completion rates, according to a study published online May 6 in JAMA Internal Medicine.Shivan J. Mehta, M.D., from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, and colleagues conducted two concurrent trials in

HealthDay 06 May at 03.39 PM

Hematopoietic Cell Transplantation Use Has Increased for All Racial Groups

Hematopoietic cell transplantation (HCT) use has increased among all racial/ethnic groups and has increased faster among non-Hispanic African Americans (NHAAs) and Hispanics than non-Hispanic Whites (NHWs), according to a study published online April 25 in Blood Advances.Nandita Khera, M.D., from the Mayo Clinic in Phoenix, and colleagues

HealthDay 03 May at 09.46 PM

Preventable Premature Death Rates Higher in Nonmetropolitan Counties

Nonmetropolitan counties had higher percentages of preventable premature deaths from the five leading causes of death during 2010 to 2022, according to research published in the May 2 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.Macarena C. García, Dr.P.H., from the U.S. Department of

HealthDay 03 May at 09.43 PM

Persistent Health Differences Seen Between Females and Males

From 1990 to 2021, there were persistent health differences between females and males, according to a study published online May 1 in The Lancet Public Health.Vedavati Patwardhan, Ph.D., from the University of California, San Diego, and colleagues compared disability-adjusted life year (DALY) rates among females and males aged older than

HealthDay 03 May at 09.39 PM

Aspirin Provides No Benefit for Breast Cancer Recurrence, Survival

Among participants with high-risk nonmetastatic breast cancer, daily aspirin use did not improve the risk for breast cancer recurrence or survival in early follow-up, according to a study published online April 29 in the Journal of the American Medical Association.Wendy Y. Chen, M.D., from the Dana-Farber Cancer Institute in Boston, and c

HealthDay 03 May at 03.57 PM

Overall Cancer Risk Not Increased for Children Born After Assisted Reproduction

The overall risk for cancer is not increased for children born after medically assisted reproduction (MAR), according to a study published online May 2 in JAMA Network Open.Paula Rios, M.D., Ph.D., from the French National Agency for Medicines and Health Products Safety in Saint-Denis, and colleagues compared the risk for cancer overall a

HealthDay 03 May at 03.54 PM

2020 Cancer Screening Rates Low at Federally Qualified Health Centers

In 2020, there were major gaps in screening clients at federally qualified health centers (FQHCs) for various types of cancer when compared with the general population, according to a study published online April 29 in&nbsp;JAMA Internal Medicine.Trisha L. Amboree, Ph.D., from the University of Texas MD Anderson Cancer Center in Houston,

HealthDay 03 May at 03.41 PM

Plant-Based Diet May Aid Prostate Cancer Outcomes

Consuming a primarily plant-based diet may be associated with better cancer-specific health outcomes among men with prostate cancer, according to a study published online May 1 in&nbsp;JAMA Network Open.Vivian N. Liu, from the University of California, San Francisco, and colleagues examined whether postdiagnostic plant-based dietary patte

HealthDay 03 May at 03.35 PM

CD7 Expression Tied to Poorer Outcomes With Newly Diagnosed Leukemia

CD7 expression is associated with poorer outcomes in patients with newly diagnosed acute myeloid leukemia (AML), according to a study published online April 11 in the British Journal of Haematology.Wei-Ying Jen, B.M., B.Ch., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues collected flow cytometry data on

HealthDay 03 May at 03.24 PM

Physical Activity in Middle Age Improves Health Among Women

FRIDAY, May 3, 2024 (HealthDay News) --&nbsp;Adherence to physical activity guidelines during middle age appears to improve health-related quality of life among women, according to a study published online May 2 in PLOS Medicine.Binh Nguyen, Ph.D., of the University of Sydney, and colleagues evaluated data from 11,336 participants in the Australian Longitudinal Study on Women's

HealthDay 03 May at 03.22 PM

Extending Interval Between Colonoscopies Feasible After Negative Result

For individuals without a family history of colorectal cancer (CRC), increasing the interval between colonoscopies for those with a first colonoscopy with negative findings seems safe and can avoid unnecessary colonoscopies, according to a study published online May 2 in JAMA Oncology.Qunfeng Liang, from the German Cancer Research Center

HealthDay 02 May at 03.54 PM

GWAS Identifies 108 Independent Risk Loci for Kidney Cancer

A genome-wide association study meta-analysis, published online April 26 in Nature Genetics, has identified 63 susceptibility regions containing 108 independent risk loci for kidney cancer.Mark P. Purdue, Ph.D., from the National Cancer Institute in Rockville, Maryland, and colleagues conducted a multi-ancestry genome-wide association s

HealthDay 02 May at 03.51 PM

Neoadjuvant Chemohormonal Therapy Aids Locally Advanced Prostate Cancer

For patients with locally advanced prostate cancer, neoadjuvant chemohormonal therapy (NCHT) is beneficial for biochemical progression-free survival (bPFS), according to a study published online May 1 in The Journal of Urology.Hongyang Qian, from Shanghai Jiao Tong University, and colleagues conducted a randomized trial recruiting 141 p

HealthDay 02 May at 03.47 PM

Recombinant ADAMTS13 Effective, Safe in Congenital Thrombotic Thrombocytopenic Purpura

THURSDAY, May 2, 2024 (HealthDay News) --&nbsp;Prophylaxis with recombinant ADAMTS13 in patients with congenital thrombotic thrombocytopenic purpura (TTP) leads to ADAMTS13 activity reaching approximately 100 percent of normal levels, according to a study published in the May 2 issue of the New England Journal of Medicine.Marie Scully, M.D., of the University College London Hos

HealthDay 02 May at 03.34 PM

Long-Term Study of Postmenopausal Women Does Not Support Many Preventive Therapies

The longitudinal Women's Health Initiative trials do not support hormone therapy for cardiovascular disease prevention, calcium and vitamin D supplementation for universal fracture prevention, or a low-fat diet for cancer prevention, according to a review published online May 1 in the Journal of the American Medical Association.JoAnn E.

HealthDay 02 May at 02.24 PM

EPA Earmarks $3 Billion to Replace Lead Pipes Nationwide

THURSDAY, May 2, 2024 (HealthDay News) — The U.S. Environmental Protection Agency (EPA) said it will spend $3 billion to help states and territories identify and replace lead water pipes."The science is clear, there is no safe level of lead exposure, and the primary source of harmful exposure in drinking water is through lead pipes," EPA Administrator <a href="https://www.epa.gov/aboute

HealthDay 02 May at 12.46 PM

Johnson & Johnson Will Pay $6.5 Billion to Settle Talc Ovarian Cancer Lawsuits

Johnson &amp; Johnson announced Wednesday that it would pay out more than $6.5 billion over the next 25 years to settle existing lawsuits claiming that its talc-containing products caused ovarian cancer.The settlement still awaits approval from claimants.Claims from consumers that baby powders and other J &amp; J talc-based products cause

HealthDay 01 May at 04.02 PM

Healthy Lifestyle Can Overcome Genetic Predisposition to Premature Death

Adherence to healthy lifestyles can largely overcome the genetic risk for a shorter lifespan, according to a study published online April 29 in BMJ Evidence Based Medicine.Zilong Bian, from the Zhejiang University&nbsp;School of Medicine in&nbsp;Hangzhou, China, and colleagues investigated associations of genetic and lifestyle factors

HealthDay 01 May at 11.19 AM

Biden Administration Could Reclassify Marijuana as Less Risky Drug

The Justice Department has recommended that marijuana be reclassified as a less dangerous drug, a move that signals a significant shift in U.S. drug policy.The proposal, first reported Tuesday by the Associated Press, still has a long way to go before it becomes official policy: First, it has to be reviewed by the White House Office of

HealthDay 30 April at 04.15 PM

USPSTF Recommends Breast Cancer Screening for Women Aged 40 to 75 Years

The U.S. Preventive Services Task Force (USPSTF) recommends breast cancer screening for women aged 40 to 75 years, but evidence is insufficient for older women and for supplemental screening for women with dense breasts. These recommendations form the basis of a final recommendation statement published online April 30 in the Journal of the Americ

HealthDay 30 April at 04.03 PM

Survival Gains Seen With Assignment to Experimental Group in Cancer Trials

For patients with solid tumors, assignment to an experimental group in trials of investigational drugs yields significant survival gains, according to a review published online April 30 in the Annuals of Internal Medicine.Renata Iskander, from McGill University in Montreal, and colleagues estimated progression-free survival and overal

HealthDay 30 April at 03.51 PM

Variation ID'd in Risk for Second Primary Cancer After Breast Cancer

The risk for second primary cancer (SPC) after breast cancer (BC) varies with gender, age, and socioeconomic status, according to a study published online April 24 in The Lancet Regional Health: Europe.Isaac Allen, from the National Health Service England in London, and colleagues estimated standardized incidence ratios (SIRs) for com

HealthDay 29 April at 04.59 PM

More Medical Lab Tests Will Soon Face Federal Scrutiny, FDA Says

Laboratory tests used by millions of Americans are soon to be classified as medical devices, and as such be regulated by the U.S. Food and Drug Administration, the agency announced Monday.The new rule does not apply to tests and kits made by big medical device manufacturers -- those already face FDA review. Instead, the agency is widenin

HealthDay 29 April at 04.20 PM

People With Opioid Use Disorder Less Likely to Receive Palliative Care

People with opioid use disorder (OUD) are less likely to receive palliative care during the last 90 days before death, according to a study published online April 29 in CMAJ, the journal of the Canadian Medical Association.Jenny Lau, M.D., from the University Health Network in Toronto, and colleagues conducted a cohort study using heal

HealthDay 29 April at 04.03 PM

Cabozantinib Promising for Metastatic Pheochromocytomas, Paragangliomas

For patients with metastatic pheochromocytomas and paragangliomas (MPPGs), an antiangiogenic multi-tyrosine kinase inhibitor, cabozantinib, is promising, according to a study published online April 9 in The Lancet Oncology.Camilo Jimenez, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted

HealthDay 29 April at 11.12 AM

Biden Administration Delays Menthol Cigarette Ban

A long-awaited ban on menthol cigarettes has been delayed indefinitely, the Biden administration said Friday.“This rule has garnered historic attention, and the public comment period has yielded an immense amount of feedback, including from various elements of the civil rights and criminal justice movement,” U.S. Health and Human Service Secret

HealthDay 26 April at 02.58 PM

Cabozantinib Promising for Advanced Adrenocortical Carcinoma

For patients with advanced adrenocortical carcinoma, cabozantinib shows promising efficacy, according to a study published online April 9 in The Lancet Oncology.Matthew T. Campbell, M.D., from The University of Texas MD Anderson Cancer Center in Houston, and colleagues conducted a single-arm, phase 2 trial in adults with advanced adren

HealthDay 26 April at 02.20 PM

FDA Approves Anktiva for BCG-Unresponsive, Non-Muscle Invasive Bladder Cancer

The U.S. Food and Drug Administration has approved Anktiva (N-803, or nogapendekin alfa inbakicept-pmln) plus Bacillus Calmette-Guérin (BCG) for the treatment of patients with BCG-unresponsive, non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ, with or without papillary tumors.Anktiva is a first-in-class interleukin-15 agonist i

HealthDay 25 April at 03.23 PM

Exa-Cel Eliminates Vaso-Occlusive Crises in Most Sickle Cell Patients

For almost all patients with sickle cell disease, treatment with exagamglogene autotemcel (exa-cel) eliminates vaso-occlusive crises, according to a study published in the April 24 issue of the New England Journal of Medicine.Haydar Frangoul, M.D., from the Sarah Cannon Research Institute at the Children's Hospital at TriStar Centenn

HealthDay 25 April at 03.16 PM

CD7 CAR T-Cell Therapy, Stem-Cell Transplant Beneficial for CD7-Positive Tumors

For patients with relapsed or refractory CD7-positive leukemia or lymphoma, sequential CD7 chimeric antigen receptor (CAR) T-cell therapy followed by haploidentical hematopoietic stem-cell transplantation (HSCT) is safe and effective, with remission seen for most patients, according to a study published in the April 25 issue of the New England J

HealthDay 25 April at 03.01 PM

AI Model Reduces False Positives in Screening Mammograms

A semiautonomous breast cancer screening system reduces false positives with screening mammograms, according to a study published online April 10 in Radiology: Artificial Intelligence.Stefano Pedemonte, Ph.D., from Whiterabbit.ai in Santa Clara, California, and colleagues evaluated the ability of a semiautonomous artificial intellige

HealthDay 24 April at 04.00 PM

Mortality Up for Breast Cancer Diagnosed Five to <10 Years After Childbirth

Young-onset breast cancer (YOBC) with germline BRCA pathogenic variants (PVs) is associated with an increased risk for all-cause mortality if diagnosed within 10 years after childbirth, according to a study published online April 19 in JAMA Network Open.Zhenzhen Zhang, Ph.D., M.P.H., from the Oregon Health &amp; Science Uni

HealthDay 24 April at 03.57 PM

GLP1 Receptor Agonist Use Does Not Seem to Increase Risk for Thyroid Cancer

Glucagon-like peptide 1 (GLP1) receptor agonist use does not appear to be associated with an increased risk for thyroid cancer, according to a study published online April 10 in The BMJ.Björn Pasternak, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined whether use of a GLP1 receptor agonist is associa

HealthDay 24 April at 03.50 PM

Seafood Consumption Tied to 'Forever Chemical' Exposure Risk

Northeastern U.S. seafood consumers may be exposed to per- and polyfluoroalkyl substance (PFAS) concentrations that potentially pose a health risk, according to a study published online April 12 in Exposure and Health.Kathryn A. Crawford, Ph.D., from the Environmental Studies Program at Middlebury College in Vermont, and colleagues

HealthDay 23 April at 04.05 PM

Few Cancer Survivors Fully Adherent to ACS Nutrition and Physical Activity Guidelines

Only 4 percent of cancer survivors are fully adherent to current American Cancer Society (ACS) nutrition and physical activity guidelines, according to a study published online April 18 in JAMA Oncology.Carter Baughman, M.D., from Beth Israel Deaconess Medical Center in Boston, and colleagues conducted a cross-sectional study using da

HealthDay 23 April at 03.56 PM

Higher Dietary Quality at Breast Cancer Diagnosis Linked to Lower CVD Risk

Higher diet quality at diagnosis of breast cancer is associated with a lower risk for cardiovascular disease (CVD) events and death, especially the Dietary Approaches to Stop Hypertension diet quality index, according to a study published online April 17 in JNCI Cancer Spectrum.Isaac J. Ergas, Ph.D., M.P.H., from Kaiser Permanente Nor

HealthDay 22 April at 10.48 PM

Alecensa Approved as First and Only ALK Inhibitor for Non-Small Cell Lung Cancer

The U.S. Food and Drug Administration has approved Alecensa (alectinib) as adjuvant treatment following tumor resection in patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC).The approval was based on positive results from the phase 3 ALINA study that showed Alecensa reduced the risk for disease recurrence

HealthDay 22 April at 03.36 PM

Aspirin May Enhance Immunosurveillance Against Colorectal Cancer

Aspirin may promote an immune response against cancer, with fewer nodal metastases and higher infiltration of tumor-infiltrating lymphocytes among aspirin users with colorectal cancer (CRC), according to a study published online April 22 in Cancer.Ottavia De Simoni, M.D., from Veneto Institute of Oncology IOV‐IRCCS in Padova, Italy, an

HealthDay 22 April at 03.15 PM

New Prostate Cancer Urine Test Has High Diagnostic Accuracy

A new prostate cancer test has higher diagnostic accuracy for high-grade disease than current guideline-endorsed biomarkers, according to a study published online April 18 in JAMA Oncology.Jeffrey J. Tosoian, M.D., M.P.H., from Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues developed a multiplex urinary pa

HealthDay 22 April at 12.18 PM

EPA Designates Two 'Forever Chemicals' as Hazardous

Two common PFAS "forever chemicals" have been deemed hazardous substances by the Environmental Protection Agency.The new designation, enacted under the country's <a href="https://www.epa.gov/laws-regulations/summary-comprehensive-environmental-response-compensation-and-liability-act#:~:text=The%20Comprehensive%20Environmental%20Response%2C%20Co

HealthDay 19 April at 10.18 PM

Neighborhood Disadvantage Tied to Shorter Breast Cancer-Specific Survival

Neighborhood disadvantage is associated with shorter breast cancer-specific survival, according to a study published online April 18 in JAMA Network Open.Neha Goel, M.D., M.P.H., from the University of Miami Miller School of Medicine, and colleagues examined whether neighborhood disadvantage is associated with shorter breast cancer-spe

HealthDay 19 April at 03.53 PM

Mortality Down for Rectal Cancer Surgery at NAPRC-Accredited Hospitals

National Accreditation Program for Rectal Cancer (NAPRC)-accredited hospitals have lower risk-adjusted mortality and morbidity for patients undergoing major rectal cancer surgery, according to a study published online March 28 in the Journal of the American College of Surgeons.Calista M. Harbaugh, M.D., from the University of Michigan

HealthDay 19 April at 03.41 PM

Review Explores Cutaneous Manifestations of Myelodysplastic Syndrome

Cutaneous manifestations of myelodysplastic syndrome (MDS) are described in a perspective piece published in the April issue of Skin Health and Disease.Xiang Li Tan, M.B.B.S., from St. George's University Hospitals NHS Foundation Trust in London, and colleagues conducted a systematic review to examine the prevalence, types, and prognos

HealthDay 18 April at 10.54 PM

American Association for Cancer Research, April 5-10

The annual meeting of the American Association for Cancer Research was held this year from April 5 to 10 in San Diego, drawing approximately 19,000 participants from around the world, including scientists, cancer survivors, clinicians, allied health professionals, and industry professionals. The conference highlighted recent

HealthDay 18 April at 10.39 PM

High Levels of Pesticides Found in 20 Percent of Fruits, Vegetables

Nearly one-fifth of fresh, frozen, and canned fruits and vegetables that Americans eat contain concerning levels of pesticides, posing significant risks from produce such as strawberries, green beans, bell peppers, blueberries, and potatoes, according to a review published by Consumer Reports."One food in particular, green beans, had

HealthDay 18 April at 03.52 PM

Tumor-Infiltrating Lymphocyte Abundance Prognostic in Early-Stage TNBC

For patients with early-stage triple-negative breast cancer (TNBC) who undergo surgery without chemotherapy, tumor-infiltrating lymphocyte (TIL) abundance is associated with improved survival, according to a study published online April 2 in the Journal of the American Medical Association.Roberto A. Leon-Ferre, M.D., from the Mayo Cl

HealthDay 18 April at 03.47 PM

Detection of Serrated Polyps Improved With Propofol During Colonoscopy

Propofol sedation during colonoscopy seems to be associated with improved detection of serrated polyps, according to a study published online April 17 in Anesthesiology.Aurora N. Quaye, M.D., from Maine Medical Center in Portland, and colleagues conducted a retrospective cohort study using observational data for patients aged older t

HealthDay 18 April at 03.41 PM

Improvement Seen in Survival With Adjuvant Pembrolizumab in Kidney Cancer

For patients with clear-cell renal cell carcinoma, adjuvant pembrolizumab is associated with a significant and clinically meaningful improvement in overall survival, according to a study published in the April 18 issue of the New England Journal of Medicine.Toni K. Choueiri, M.D., from the Dana-Farber Cancer Institute and Ha

HealthDay 18 April at 03.08 PM

Ending Specialized Follow-Up Feasible in Asymptomatic, Low-Risk Leukemia

For select patients with asymptomatic, lower-risk chronic lymphocytic leukemia, ending specialized follow-up (sFU) is feasible and safe, according to a study published in the March 1 issue of Blood Advances.Christian Brieghel, M.D., Ph.D., from Copenhagen University Hospital, Rigshospitalet in Denmark, and colleagues examined the fea

HealthDay 17 April at 03.42 PM

Bilateral Wilms Tumors That Grow During Chemo Mostly Stromal-Predominant

Bilateral Wilms tumors (BWTs) that increase in size during neoadjuvant chemotherapy, especially in younger patients, are most often stromal-predominant, according to a study published online March 27 in the Journal of the National Cancer Institute.Colton Duncan, from the Dana-Farber Cancer Institute/Boston Children's Hospital, and c

HealthDay 17 April at 03.37 PM

Subclassification Can Tailor Surveillance for Pancreatic Adenocarcinoma

Subclassification of individuals at high risk for pancreatic adenocarcinoma (PC) can enable the development of surveillance approaches better tailored to risk, according to a study published online April 16 in the Journal of the National Comprehensive Cancer Network.George Zogopoulos, M.D., Ph.D., from McGill University Health Cente

HealthDay 16 April at 04.11 PM

Risk for Second Primary Breast Cancer Low in Certain Young Breast Cancer Patients

Young breast cancer (BC) survivors (40 years or younger) without a pathogenic variant (PV) have a low risk for developing second primary BC (SPBC), according to a study published online April 11 in JAMA Oncology.Kristen D. Brantley, Ph.D., M.P.H., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues estimated t

HealthDay 16 April at 03.57 PM

Midlife Mortality Higher in U.S. Than Other High-Income Countries

Working-age adults in the United States are dying at higher rates than their peers in high-income countries, according to a study published online March 21 in the&nbsp;International Journal of Epidemiology.Jennifer Beam Dowd, Ph.D., from the University of Oxford in the United Kingdom, and colleagues synthesized cause-specific mortalit

HealthDay 16 April at 03.49 PM

Patient Enrollment in Cancer Treatment Trials About 7 Percent

Patient enrollment in cancer treatment trials is 7.1 percent, higher than historical estimates, according to a study published online April 2 in the&nbsp;Journal of Clinical Oncology.Joseph M. Unger, Ph.D., from the Fred Hutchinson Cancer Center in Seattle, and colleagues provided contemporary estimates of clinical trial participation

HealthDay 15 April at 10.55 PM

2011 to 2020 Saw Increase in Annual Prescription Meds Expenditures

From 2011 to 2020, there was an increase in total annual prescription medication expenditures, with antimetabolic agents the most costly category, according to a study published in the April issue of Research in Social and Administrative Pharmacy.Whanhui Chi, from the University of Houston College of Pharmacy, and colleagues calculated

HealthDay 15 April at 10.52 PM

Childhood Cancer Survivors Face Socioeconomic Difficulties

Childhood cancer survivors face socioeconomic difficulties, according to a review published online April 15 in JAMA Pediatrics.Márk Viktor Hernádfői, M.D., from the Centre for Translational Medicine at Semmelweis University in Budapest, Hungary, and colleagues conducted a systematic review and meta-analysis of 280 articles, reporting o

HealthDay 15 April at 03.44 PM

One-Third of Young Women With Breast Cancer Delay Care

A significant proportion of young women with breast cancer experience diagnostic delay, most often related to patient factors, according to a study presented at the annual meeting of the American Society of Breast Surgeons, held from April 6 to 10 in Orlando, Florida.Katherine Fleshner, M.D., from the University of Calgary in Alberta, Canada, a

HealthDay 15 April at 11.16 AM

U.S. Medical Drug Shortages Reach Record High

Americans are facing more shortages of the drugs they need for medical care than ever before, a national pharmacy database shows.The American Society of Health-System Pharmacists (ASHSP) and the University of Utah Drug Information Service started tracking drug shortages as far back as 2001. Their latest <a href="https://www.ashp.org/drug

HealthDay 12 April at 03.55 PM

AACR: At-Home HPV Testing Boosts Cervical Cancer Screening Participation

Mailed at-home self-sampling for&nbsp;human papillomavirus&nbsp;(HPV) testing&nbsp;increases cervical cancer screening participation in underscreened populations by almost threefold, according to a study presented at the annual meeting of the American Association for Cancer Research, held from April 5 to 10 in San Diego.Jane R. Montealegre, Ph.

HealthDay 12 April at 03.50 PM

Adjuvant Alectinib Improves Disease-Free Survival in Lung Cancer

Adjuvant alectinib improves disease-free survival compared with platinum-based chemotherapy among patients with resected ALK-positive non-small cell lung cancer (NSCLC), according to a study published in the April 11 issue of the New England Journal of Medicine.Yi-Long Wu, M.D., from the Guangdong Lung Cancer Institute in Guan

HealthDay 12 April at 03.31 PM

Microwave Ablation Feasible for T1N0M0 Papillary Thyroid Carcinoma

For patients with multifocal papillary thyroid carcinoma (PTC), the rates of progression-free survival (PFS) do not differ between microwave ablation (MWA) and surgical resection (SR), according to a study published online April 2 in Radiology.Zhen-Long Zhao, M.D., from the China-Japan Friendship Hospital in Beijing, and colleagues com

HealthDay 11 April at 10.01 PM

Barriers to Mammogram Use Include Adverse Social Demographics

Among women aged 50 to 74 years, specific adverse social determinants of health (SDOH) and health-related social needs (HRSNs) are associated with not having had a mammogram in the past two years, according to research published in the April 9 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Week

HealthDay 11 April at 04.10 PM

Decline Seen in Patients Undergoing Surgery for Colon, Rectal Cancer in 2020

There was a 17.3 percent decrease in the number of patients undergoing surgery for colon and rectal cancer in the first year of the COVID-19 pandemic, according to a study published online March 25 in the Journal of the American College of Surgeons.Davide Ferrari, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues use

HealthDay 11 April at 12.34 PM

Consumer Reports Warns of Concerning Levels of Lead, Sodium in Lunchables

Lunchables, those ubiquitous plastic packets of cheese, deli meats and crackers that many parents choose for convenience, contain concerning levels of lead and sodium, Consumer Reports warns.To arrive at that conclusion, the advocacy group tested Lunchables made by Kraft Heinz, as well as similar lunch and snack products from other manufactur

HealthDay 10 April at 03.59 PM

HYPORT Noninferior for GU, GI Toxicity in Prostate Cancer

For patients with prostate cancer, hypofractionated postprostatectomy radiotherapy (HYPORT) is noninferior to conventionally fractionated postprostatectomy radiotherapy (COPORT) in terms of gastrointestinal (GI) or genitourinary (GU) toxicity at two years, according to a study published online March 14 in JAMA Oncology.Mark K. Buyyo

HealthDay 10 April at 03.45 PM

Premastectomy Radiotherapy Followed by Immediate Breast Reconstruction Demonstrates Safety

Premastectomy radiotherapy (PreMRT) and regional node irradiation (RNI) followed by immediate breast reconstruction (IMBR) is feasible and safe, according to a study published online April 5 in&nbsp;JAMA Network Open.Mark V. Schaverien, M.D., from University of Texas MD Anderson Cancer Center in Houston, and colleagues assessed the

HealthDay 10 April at 11.56 AM

EPA Sets Strict Limit on PFAS 'Forever Chemicals' in U.S. Drinking Water

The Environmental Protection Agency announced Wednesday that it has finalized a first-ever rule that will drastically lower the amount of PFAS, also known as "forever chemicals," in the nation's drinking water.“Drinking water contaminated with PFAS has plagued communities across this country for too long,”&nbsp;EPA Administrator <a href="htt

HealthDay 09 April at 10.49 PM

AACR: Novel Personalized Vaccine Feasible for Head and Neck Cancer

The novel viral-based personalized cancer vaccine, TG4050, which encodes up to 30 patient- and tumor-specific sequences is feasible and safe for patients with resected head and neck squamous cell carcinoma, according to a study presented at the annual meeting of the American Association for Cancer Research, held from April 5 to 10 in San Diego.

HealthDay 09 April at 10.44 PM

FDA Approves Abecma for Relapsed, Refractory Multiple Myeloma

The U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.The approval is for the treatment of adult patients with relapsed or refractory multiple myeloma after two or more prior lines of therapy, including an immunomod

HealthDay 09 April at 10.41 PM

EPA Issues New Rules to Reduce Airborne Toxins From Chemical Plants

New rules issued Tuesday by the Environmental Protection Agency are aimed at reducing airborne toxins for people living near certain factories.The new rules "will significantly reduce toxic air pollution from chem

HealthDay 09 April at 03.23 PM

AACR: Accelerated Aging Linked to Incidence of Early-Onset Cancer

Accelerated aging (AA) is increasing and is associated with an increased incidence of early-onset solid tumors, according to a study presented at the annual meeting of the American Association for Cancer Research, held from April 5 to 10 in San Diego.Ruiyi Tian, M.P.H., from the Washington University School of Medicine in St. Louis, and colleag

HealthDay 09 April at 03.20 PM

Caring for Child With Cancer Increases Mental Health Care Utilization for Parents

Privately insured parents caring for a child with cancer have a higher likelihood of utilizing mental health (MH) care than other parents, according to a study published online April 2 in&nbsp;JAMA Network Open.Xin Hu, Ph.D., from University of Virginia in Charlottesville, and colleagues assessed use of MH services among parents of chi

HealthDay 08 April at 10.35 PM

AACR: Exosome-Based miRNA Assay Can Detect Pancreatic Cancer

An exosome-based liquid biopsy assay can distinguish patients with pancreatic ductal adenocarcinoma (PDAC) from healthy donors (HDs), according to a study presented at the annual meeting of the American Association for Cancer Research, held from April 5 to 10 in San Diego.Caiming Xu, M.D., Ph.D., from the Beckman Research Institute of The City o

HealthDay 08 April at 10.30 PM

FDA Approves New Antibiotic for Three Indications

The U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults with Staphylococcus aureus bloodstream infections, adults with acute bacterial skin and skin structure infections, and adult and pediatric patients (age 3 months

HealthDay 08 April at 03.34 PM

AACR: Little Benefit Seen for Cancer Drugs Given Accelerated Approval

Most cancer drugs granted accelerated approval do not demonstrate clinical benefit, according to a study published online April 7 in the Journal of the American Medical Association to coincide with the annual meeting of the American Association for Cancer Research, held from April 5 to 10 in San Diego.Ian T.T. Liu, M.D., J.D., M.P.H., f

HealthDay 08 April at 03.31 PM

AACR: Cadonilimab Plus Chemo Beneficial for Gastric Adenocarcinoma

For patients with gastric/gastroesophageal junction (G/GEJ) adenocarcinoma, cadonilimab plus chemotherapy is associated with improved overall survival and progression-free survival, according to a study presented at the annual meeting of the American Association for Cancer Research, held from April 5 to 10 in San Diego.Jiafu Ji, M.D., Ph.D., fro

HealthDay 08 April at 03.25 PM

Single Invitation for PSA Screening Cuts Prostate Cancer Deaths

A single invitation for prostate-specific antigen (PSA) screening is associated with reduced prostate cancer deaths, although the absolute reduction is small, according to a study published online April 6 in the Journal of the American Medical Association to coincide with the 39th Annual European Association of Urology Congress, held from Apri

HealthDay 08 April at 03.22 PM

Immersive Virtual Reality Beneficial for Pain Relief in Cancer

For hospitalized patients with cancer, immersive virtual reality (VR) distraction therapy is associated with a greater reduction in pain compared with an active control, according to a study published online April 8 in Cancer.Hunter Groninger, M.D., from MedStar Health Research Institute in Hyattsville, Maryland, and colleagues conducte

HealthDay 05 April at 10.52 PM

EEG Most Beneficial Tool for Managing CAR T-Cell-Related Neurotoxicity

For patients with immune effector cell-associated neurotoxicity syndrome (ICANS) due to chimeric antigen receptor (CAR) T-cell therapy, electroencephalogram (EEG) has the greatest therapeutic impact, according to a study published online March 19 in Blood Advances.Mattéo Mauget, M.D., from the University Hospital of Rennes in France, an

HealthDay 05 April at 04.06 PM

Number of Prostate Cancer Cases Set to Increase to 2.9 Million in 2040

The number of new prostate cancer cases is set to increase to 2.9 million in 2040, according to a study published online April 4 in The Lancet.Nicholas D. James, M.B.B.S., Ph.D., from the Institute of Cancer Research in London, and colleagues reported projections of prostate cancer cases in 2040 based on data for demographic changes wor